EP1181032A4 - System for exsanguinous metabolic support of an organ or tissue - Google Patents

System for exsanguinous metabolic support of an organ or tissue

Info

Publication number
EP1181032A4
EP1181032A4 EP00923303A EP00923303A EP1181032A4 EP 1181032 A4 EP1181032 A4 EP 1181032A4 EP 00923303 A EP00923303 A EP 00923303A EP 00923303 A EP00923303 A EP 00923303A EP 1181032 A4 EP1181032 A4 EP 1181032A4
Authority
EP
European Patent Office
Prior art keywords
organ
tissue
metabolic support
exsanguinous metabolic
exsanguinous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00923303A
Other languages
German (de)
French (fr)
Other versions
EP1181032A1 (en
Inventor
Lauren Brasile
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Breonics Inc
Original Assignee
Breonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Breonics Inc filed Critical Breonics Inc
Publication of EP1181032A1 publication Critical patent/EP1181032A1/en
Publication of EP1181032A4 publication Critical patent/EP1181032A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
EP00923303A 1999-04-14 2000-04-13 System for exsanguinous metabolic support of an organ or tissue Withdrawn EP1181032A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12925799P 1999-04-14 1999-04-14
US129257P 1999-04-14
PCT/US2000/009894 WO2000061166A1 (en) 1999-04-14 2000-04-13 System for exsanguinous metabolic support of an organ or tissue

Publications (2)

Publication Number Publication Date
EP1181032A1 EP1181032A1 (en) 2002-02-27
EP1181032A4 true EP1181032A4 (en) 2004-08-25

Family

ID=22439141

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00923303A Withdrawn EP1181032A4 (en) 1999-04-14 2000-04-13 System for exsanguinous metabolic support of an organ or tissue

Country Status (4)

Country Link
EP (1) EP1181032A4 (en)
AU (1) AU4345400A (en)
CA (2) CA2376607C (en)
WO (1) WO2000061166A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582953B2 (en) 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US20040038192A1 (en) * 1999-04-14 2004-02-26 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
KR101012952B1 (en) * 2001-02-14 2011-02-08 안트로제네시스 코포레이션 Post-partum mammalian placenta, its use and placental stem cells therefrom
WO2003088748A1 (en) * 2002-04-15 2003-10-30 Beth Israel Deaconess Medical Center Use of heme oxygenase-1 and products of heme degradation
US8734867B2 (en) 2007-12-28 2014-05-27 Liveleaf, Inc. Antibacterial having an extract of pomegranate combined with hydrogen peroxide
US9192635B2 (en) 2011-06-24 2015-11-24 Liveleaf, Inc. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide
US8716351B1 (en) 2012-12-23 2014-05-06 Liveleaf, Inc. Methods of treating gastrointestinal spasms
CA3164819A1 (en) * 2014-03-26 2015-10-01 Tevosol, Inc. Apparatus for maintenance of harvested hearts for transplanting
US10091986B2 (en) 2016-05-09 2018-10-09 Xor-Labs Toronto Inc. Organ perfusion device and method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0376763A2 (en) * 1988-10-26 1990-07-04 McKelvey, Karen A device for transportation of human organs used for transplantation
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
WO1995031897A1 (en) * 1994-05-20 1995-11-30 Vec Tec, Inc. Method and apparatus monitoring viability of transplantable organs
WO1995031944A1 (en) * 1994-05-20 1995-11-30 Vec Tec, Inc. Methods rendering grafts nonthrombogenic and substantially nonimmunogenic
US5599659A (en) * 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
US5843024A (en) * 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484789A (en) * 1989-10-31 1996-01-16 The University Of North Carolina At Chapel Hill Calcium channel blockers to improve preservation of organs stored for transplantation
US5747469A (en) * 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0376763A2 (en) * 1988-10-26 1990-07-04 McKelvey, Karen A device for transportation of human organs used for transplantation
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5599659A (en) * 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
US5702881A (en) * 1993-03-16 1997-12-30 Alliance Pharmaceutical Corp. Method and solution for organ preservation comprising retinal-derived growth factor, cyclodextrin, mucopolysaccharide and fluorocarbon
WO1995031897A1 (en) * 1994-05-20 1995-11-30 Vec Tec, Inc. Method and apparatus monitoring viability of transplantable organs
WO1995031944A1 (en) * 1994-05-20 1995-11-30 Vec Tec, Inc. Methods rendering grafts nonthrombogenic and substantially nonimmunogenic
US5699793A (en) * 1994-05-20 1997-12-23 Breonics Inc. Diagnostic methods for monitoring functional charcteristics of an organ intended for transplantation
US5843024A (en) * 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
D'ALESSANDRO A M ET AL: "Organ preservation", PROBLEMS IN GENERAL SURGERY 1998 UNITED STATES, vol. 15, no. 3, 1998, pages 10 - 20, XP009032447, ISSN: 0739-8328 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, BACIEWICZ F A JR ET AL: "PHARMACOKINETICS AND TOXICITY OF ISOLATED PERFUSION OF LUNG WITH DOXORUBICIN", XP002285467, Database accession no. PREV199191087164 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1997, DE ROOS W K ET AL: "Isolated-organ perfusion for local gene delivery: Efficient adenovirus-mediated gene transfer into the liver", XP002285466, Database accession no. PREV199799409497 *
GENE THERAPY, vol. 4, no. 1, 1997, pages 55 - 62, ISSN: 0969-7128 *
JOURNAL OF SURGICAL RESEARCH, vol. 50, no. 2, 1991, pages 124 - 128, ISSN: 0022-4804 *
MEIJER D K F ET AL: "Isolated perfused liver as a tool to study the disposition of peptides, liver first-pass effects, and cell-specific drug delivery", JOURNAL OF CONTROLLED RELEASE, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 46, no. 1-2, 5 May 1997 (1997-05-05), pages 139 - 156, XP004096319, ISSN: 0168-3659 *
See also references of WO0061166A1 *

Also Published As

Publication number Publication date
WO2000061166A9 (en) 2002-01-31
CA2376607C (en) 2014-06-10
CA2376607A1 (en) 2000-10-19
CA2847723A1 (en) 2000-10-19
EP1181032A1 (en) 2002-02-27
WO2000061166A1 (en) 2000-10-19
AU4345400A (en) 2000-11-14

Similar Documents

Publication Publication Date Title
AU7523600A (en) Surgical system for tissue fixation
AU5440801A (en) Device for prediction of human or mammalian labour
GB2353220B (en) Surgical instrument
GB2344283B (en) Patient support
GB9929407D0 (en) Patient support
AU7420000A (en) Fixation system for bones
AU5276600A (en) Kit for flushing medical devices and method of preparing the flushing solution
GB2370391B (en) System of knowledge architecture
DE60032256D1 (en) IMPROVED VISIBILITY OF MEDICAL IMPLANTS
IL141755A0 (en) Medical implant system
AU4665300A (en) Novel organ preservation solution
IL129398A0 (en) Metabolism monitoring of body organs
AU4302101A (en) Prognostic testing of organs intended for transplantation
TW419101U (en) Structure of fastening apparatus for instrument
IL148051A0 (en) Finger-guided surgical instrument
EP1181032A4 (en) System for exsanguinous metabolic support of an organ or tissue
AU1462801A (en) Tissue specific genes of diagnostic import
IL149715A0 (en) MICROBIAL 9α-HYDROXYLATION OF STEROIDS
AU1245701A (en) System and method supporting mapping of option bindings
EP1200133A4 (en) Manipulation of tissue or organ type using the notch pathway
AU4389400A (en) Implant for temporarily fixing tissue
HUP0001890A2 (en) Tissue structure for transplantation surgery
HK1047687A1 (en) Device for coagulation of tissues
AU3212099A (en) Method for increasing the permeability of horny human tissue
TW405395U (en) Structure of rack for tissue paper

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20011112

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 5/00 B

Ipc: 7A 61K 31/70 B

Ipc: 7A 61K 38/00 A

Ipc: 7A 01N 1/02 B

Ipc: 7C 12N 15/00 B

A4 Supplementary search report drawn up and despatched

Effective date: 20040714

17Q First examination report despatched

Effective date: 20061122

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20081205