EP1377287A4 - Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases - Google Patents
Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseasesInfo
- Publication number
- EP1377287A4 EP1377287A4 EP02719009A EP02719009A EP1377287A4 EP 1377287 A4 EP1377287 A4 EP 1377287A4 EP 02719009 A EP02719009 A EP 02719009A EP 02719009 A EP02719009 A EP 02719009A EP 1377287 A4 EP1377287 A4 EP 1377287A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- proanthocyanidins
- amyloid
- alpha
- treatment
- synuclein diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Applications Claiming Priority (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US938987 | 1997-09-26 | ||
US27686601P | 2001-03-15 | 2001-03-15 | |
US276866P | 2001-03-15 | ||
US09/938,987 US6607758B2 (en) | 1997-05-15 | 2001-08-24 | Methods for inhibiting and reducing amyloid fibril formation associated with Alzheimer's Disease and other amyloidoses |
US53625 | 2001-11-02 | ||
US10/053,625 US6929808B2 (en) | 2000-11-03 | 2001-11-02 | Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from Uncaria tomentosa and related plants |
WOPCT/US05/01131 | 2001-11-02 | ||
PCT/US2001/051131 WO2002042429A2 (en) | 2000-11-03 | 2001-11-02 | Methods of isolating amyloid-inhibiting compounds and use of compounds isolated from uncaria tomentosa and related plants |
US33872101P | 2001-12-04 | 2001-12-04 | |
US338721P | 2001-12-04 | ||
US33903301P | 2001-12-10 | 2001-12-10 | |
US33896901P | 2001-12-10 | 2001-12-10 | |
US339033P | 2001-12-10 | ||
US338969P | 2001-12-10 | ||
PCT/US2002/004764 WO2002076381A2 (en) | 2001-03-15 | 2002-02-15 | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1377287A2 EP1377287A2 (en) | 2004-01-07 |
EP1377287A4 true EP1377287A4 (en) | 2007-11-14 |
Family
ID=56290250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02719009A Withdrawn EP1377287A4 (en) | 2001-03-15 | 2002-02-15 | Proanthocyanidins for the treatment of amyloid and alpha-synuclein diseases |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1377287A4 (en) |
JP (1) | JP4380991B2 (en) |
AU (1) | AU2002250117B2 (en) |
CA (1) | CA2441099C (en) |
NZ (1) | NZ528322A (en) |
WO (1) | WO2002076381A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
US7514107B2 (en) * | 2002-03-21 | 2009-04-07 | Mars, Incorporated | Treatment of diseases involving defective gap junctional communication |
PT1511710E (en) | 2002-05-31 | 2014-02-26 | Proteotech Inc | Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer s disease, type 2 diabetes, and parkinson s disease |
WO2004033448A2 (en) * | 2002-10-11 | 2004-04-22 | Proteotech, Inc. | Isolation, purification and synthesis of procyanidin b2 and uses thereof |
JP2006232670A (en) * | 2003-05-20 | 2006-09-07 | Ajinomoto Co Inc | Medicine for nervous disorder |
JP4505555B2 (en) * | 2004-03-02 | 2010-07-21 | 康 大泉 | Neurodegenerative disease therapeutic agent |
DK2004155T3 (en) * | 2006-03-29 | 2018-04-30 | Wista Lab Ltd | PROTEIN AGGREGATION INHIBITORS |
JP5443015B2 (en) * | 2008-02-19 | 2014-03-19 | 株式会社岐阜セラツク製造所 | Pharmaceutical composition |
EP2291191A4 (en) * | 2008-05-09 | 2014-01-22 | Sinai School Medicine | Methods for preventing and treating neurodegenerative diseases |
US20140179774A1 (en) * | 2012-12-26 | 2014-06-26 | Industrial Technology Research Institute | Methods for inhibition of shc-1/p66 to combat aging-related diseases |
EP3272351A4 (en) | 2015-05-11 | 2018-12-05 | Meiji Co., Ltd. | Composition for facilitating production of brain-derived neurotrophic factor |
KR102441381B1 (en) * | 2016-07-18 | 2022-09-07 | (주)아모레퍼시픽 | Composition for enhancing cognitive function comprising trans-3-O-galloyl-3,3',5,5',7- pentahydroxyflavan |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922756A (en) * | 1998-02-14 | 1999-07-13 | Chan; Marion Man-Ying | Method of inhibiting nitric oxide synthase |
WO1999045797A1 (en) * | 1998-03-12 | 1999-09-16 | Mars, Incorporated | Products containing polyphenol(s) and l-arginine to stimulate nitric oxide production |
WO2000030666A1 (en) * | 1998-11-24 | 2000-06-02 | University Of Washington | Composition and methods for inhibiting the formation of brain amyloid deposits |
WO2001049307A1 (en) * | 1999-12-30 | 2001-07-12 | Proteotech, Inc. | Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
WO1998051302A1 (en) * | 1997-05-15 | 1998-11-19 | University Of Washington | Composition and methods for treating alzheimer's disease and other amyloidoses |
AU3886200A (en) * | 1999-03-15 | 2000-10-16 | Proteotech, Inc. | Methods of treating alzheimer's disease and other amyloidoses using hypericum perforatum and derivatives thereof |
-
2002
- 2002-02-15 EP EP02719009A patent/EP1377287A4/en not_active Withdrawn
- 2002-02-15 NZ NZ528322A patent/NZ528322A/en not_active IP Right Cessation
- 2002-02-15 CA CA2441099A patent/CA2441099C/en not_active Expired - Fee Related
- 2002-02-15 WO PCT/US2002/004764 patent/WO2002076381A2/en active IP Right Grant
- 2002-02-15 JP JP2002574897A patent/JP4380991B2/en not_active Expired - Fee Related
- 2002-02-15 AU AU2002250117A patent/AU2002250117B2/en not_active Ceased
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922756A (en) * | 1998-02-14 | 1999-07-13 | Chan; Marion Man-Ying | Method of inhibiting nitric oxide synthase |
WO1999045797A1 (en) * | 1998-03-12 | 1999-09-16 | Mars, Incorporated | Products containing polyphenol(s) and l-arginine to stimulate nitric oxide production |
WO2000030666A1 (en) * | 1998-11-24 | 2000-06-02 | University Of Washington | Composition and methods for inhibiting the formation of brain amyloid deposits |
WO2001049307A1 (en) * | 1999-12-30 | 2001-07-12 | Proteotech, Inc. | Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses |
Also Published As
Publication number | Publication date |
---|---|
NZ528322A (en) | 2005-03-24 |
WO2002076381A2 (en) | 2002-10-03 |
CA2441099A1 (en) | 2002-10-03 |
AU2002250117B8 (en) | 2002-10-08 |
JP2005505497A (en) | 2005-02-24 |
JP4380991B2 (en) | 2009-12-09 |
EP1377287A2 (en) | 2004-01-07 |
AU2002250117B2 (en) | 2007-11-29 |
WO2002076381A3 (en) | 2002-11-21 |
CA2441099C (en) | 2011-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030924 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: NGUYEN, BETH, P. Inventor name: CHOI, PAULA, Y. Inventor name: CASTILLO, GERALDO, M. Inventor name: SNOW, ALAN, D. |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 3/10 20060101ALI20070717BHEP Ipc: A61P 25/28 20060101ALI20070717BHEP Ipc: A61P 25/16 20060101ALI20070717BHEP Ipc: A61K 31/353 20060101ALI20070717BHEP Ipc: A61K 31/352 20060101ALI20070717BHEP Ipc: A61K 31/35 20060101AFI20070717BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20071016 |
|
17Q | First examination report despatched |
Effective date: 20090618 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120925 |