EP1406685A1 - Hemodialyzer having improved dialysate perfusion - Google Patents
Hemodialyzer having improved dialysate perfusionInfo
- Publication number
- EP1406685A1 EP1406685A1 EP02776553A EP02776553A EP1406685A1 EP 1406685 A1 EP1406685 A1 EP 1406685A1 EP 02776553 A EP02776553 A EP 02776553A EP 02776553 A EP02776553 A EP 02776553A EP 1406685 A1 EP1406685 A1 EP 1406685A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- dialysate
- dialyzer
- interior
- inlet
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000010412 perfusion Effects 0.000 title description 6
- 239000000835 fiber Substances 0.000 claims abstract description 90
- 239000012530 fluid Substances 0.000 claims abstract description 72
- 238000000034 method Methods 0.000 claims abstract description 16
- 238000000502 dialysis Methods 0.000 claims abstract description 12
- 238000004891 communication Methods 0.000 claims abstract description 11
- 239000008280 blood Substances 0.000 claims description 37
- 210000004369 blood Anatomy 0.000 claims description 37
- 238000004382 potting Methods 0.000 claims description 12
- 238000001631 haemodialysis Methods 0.000 claims description 11
- 230000000322 hemodialysis Effects 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 11
- 229920003023 plastic Polymers 0.000 claims description 2
- 239000004033 plastic Substances 0.000 claims description 2
- 230000017531 blood circulation Effects 0.000 description 19
- 238000013461 design Methods 0.000 description 18
- 239000012528 membrane Substances 0.000 description 18
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 13
- 238000009826 distribution Methods 0.000 description 13
- 239000004202 carbamide Substances 0.000 description 12
- 230000035699 permeability Effects 0.000 description 11
- 230000008901 benefit Effects 0.000 description 10
- 238000012546 transfer Methods 0.000 description 9
- 238000004458 analytical method Methods 0.000 description 6
- 239000012510 hollow fiber Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 230000008030 elimination Effects 0.000 description 4
- 238000003379 elimination reaction Methods 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 208000001647 Renal Insufficiency Diseases 0.000 description 3
- 201000006370 kidney failure Diseases 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 108700012359 toxins Proteins 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 208000020832 chronic kidney disease Diseases 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- -1 hydrogen ions Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 210000005227 renal system Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 229940045136 urea Drugs 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
- B01D63/0233—Manufacturing thereof forming the bundle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
- A61M1/1627—Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/20—Accessories; Auxiliary operations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0496—Urine
- A61M2202/0498—Urea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/15—Detection of leaks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/10—Specific supply elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/12—Specific discharge elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2313/00—Details relating to membrane modules or apparatus
- B01D2313/21—Specific headers, end caps
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Manufacturing & Machinery (AREA)
- External Artificial Organs (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US871864 | 1992-04-20 | ||
US09/871,864 US6623638B2 (en) | 2001-06-01 | 2001-06-01 | Hemodialyzer having improved dialysate perfusion |
PCT/US2002/013043 WO2002098490A1 (en) | 2001-06-01 | 2002-04-24 | Hemodialyzer having improved dialysate perfusion |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1406685A1 true EP1406685A1 (en) | 2004-04-14 |
EP1406685B1 EP1406685B1 (en) | 2008-06-11 |
Family
ID=25358329
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02776553A Expired - Lifetime EP1406685B1 (en) | 2001-06-01 | 2002-04-24 | Hemodialyzer having improved dialysate perfusion |
Country Status (9)
Country | Link |
---|---|
US (1) | US6623638B2 (en) |
EP (1) | EP1406685B1 (en) |
JP (2) | JP4036828B2 (en) |
AR (1) | AR033170A1 (en) |
AT (1) | ATE397946T1 (en) |
DE (1) | DE60227076D1 (en) |
MX (1) | MXPA03010988A (en) |
TW (1) | TW553751B (en) |
WO (1) | WO2002098490A1 (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2954944A1 (en) | 2014-06-12 | 2015-12-16 | B. Braun Avitum AG | Dialyzer with a bundle of hollow fibres and method for producing such a hollow fibre |
US9757196B2 (en) | 2011-09-28 | 2017-09-12 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
US9888956B2 (en) | 2013-01-22 | 2018-02-13 | Angiodynamics, Inc. | Integrated pump and generator device and method of use |
US9895189B2 (en) | 2009-06-19 | 2018-02-20 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
US10448989B2 (en) | 2009-04-09 | 2019-10-22 | Virginia Tech Intellectual Properties, Inc. | High-frequency electroporation for cancer therapy |
US11707629B2 (en) | 2009-05-28 | 2023-07-25 | Angiodynamics, Inc. | System and method for synchronizing energy delivery to the cardiac rhythm |
US11723710B2 (en) | 2016-11-17 | 2023-08-15 | Angiodynamics, Inc. | Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode |
US11931096B2 (en) | 2010-10-13 | 2024-03-19 | Angiodynamics, Inc. | System and method for electrically ablating tissue of a patient |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040254513A1 (en) | 2002-04-10 | 2004-12-16 | Sherwin Shang | Conductive polymer materials and applications thereof including monitoring and providing effective therapy |
US7052480B2 (en) | 2002-04-10 | 2006-05-30 | Baxter International Inc. | Access disconnection systems and methods |
US10155082B2 (en) | 2002-04-10 | 2018-12-18 | Baxter International Inc. | Enhanced signal detection for access disconnection systems |
US7022098B2 (en) | 2002-04-10 | 2006-04-04 | Baxter International Inc. | Access disconnection systems and methods |
CA2575731C (en) * | 2003-12-24 | 2014-07-15 | Chemica Technologies, Inc. | Dialysate regeneration system for portable human dialysis |
US9254279B2 (en) * | 2004-05-12 | 2016-02-09 | Baxter International Inc. | Nitric oxide scavengers |
US7534349B2 (en) * | 2005-09-02 | 2009-05-19 | Nephros, Inc. | Dual stage ultrafilter devices in the form of portable filter devices, shower devices, and hydration packs |
US7775375B2 (en) * | 2005-11-03 | 2010-08-17 | Medica S.R.L. | Redundant ultrafiltration device |
WO2007138659A1 (en) | 2006-05-26 | 2007-12-06 | National University Corporation Nagoya University | External fixator |
US10245098B2 (en) | 2008-04-29 | 2019-04-02 | Virginia Tech Intellectual Properties, Inc. | Acute blood-brain barrier disruption using electrical energy based therapy |
US9198733B2 (en) | 2008-04-29 | 2015-12-01 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for electroporation-based therapies |
US9283051B2 (en) | 2008-04-29 | 2016-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating a treatment volume for administering electrical-energy based therapies |
US11272979B2 (en) | 2008-04-29 | 2022-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US11254926B2 (en) | 2008-04-29 | 2022-02-22 | Virginia Tech Intellectual Properties, Inc. | Devices and methods for high frequency electroporation |
US10238447B2 (en) | 2008-04-29 | 2019-03-26 | Virginia Tech Intellectual Properties, Inc. | System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress |
US9867652B2 (en) | 2008-04-29 | 2018-01-16 | Virginia Tech Intellectual Properties, Inc. | Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds |
WO2009134876A1 (en) | 2008-04-29 | 2009-11-05 | Virginia Tech Intellectual Properties, Inc. | Irreversible electroporation to create tissue scaffolds |
US10117707B2 (en) | 2008-04-29 | 2018-11-06 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US10702326B2 (en) | 2011-07-15 | 2020-07-07 | Virginia Tech Intellectual Properties, Inc. | Device and method for electroporation based treatment of stenosis of a tubular body part |
US8992517B2 (en) | 2008-04-29 | 2015-03-31 | Virginia Tech Intellectual Properties Inc. | Irreversible electroporation to treat aberrant cell masses |
US10272178B2 (en) | 2008-04-29 | 2019-04-30 | Virginia Tech Intellectual Properties Inc. | Methods for blood-brain barrier disruption using electrical energy |
US20100125235A1 (en) * | 2008-06-16 | 2010-05-20 | Triaxis Medical Devices, Inc. | Blood Treatment Apparatus Having Branched Flow Distribution |
EP2313125B1 (en) * | 2008-07-15 | 2016-04-06 | Mirimedical Llc | Double fiber bundle dialyzer |
US8114043B2 (en) | 2008-07-25 | 2012-02-14 | Baxter International Inc. | Electromagnetic induction access disconnect sensor |
US11638603B2 (en) | 2009-04-09 | 2023-05-02 | Virginia Tech Intellectual Properties, Inc. | Selective modulation of intracellular effects of cells using pulsed electric fields |
US11382681B2 (en) | 2009-04-09 | 2022-07-12 | Virginia Tech Intellectual Properties, Inc. | Device and methods for delivery of high frequency electrical pulses for non-thermal ablation |
US8425455B2 (en) | 2010-03-30 | 2013-04-23 | Angiodynamics, Inc. | Bronchial catheter and method of use |
US8388566B2 (en) | 2010-04-29 | 2013-03-05 | Sorin Group Italia, S.r.l. | Oxygenator with integrated arterial filter including filter frame |
EP2612685B1 (en) | 2010-08-19 | 2014-10-08 | Sorin Group Italia S.r.l. | Blood processing unit with modified flow path |
EP2524712B1 (en) | 2011-05-17 | 2018-12-12 | Sorin Group Italia S.r.l. | Blood processing unit with cross blood flow |
JP6297706B2 (en) | 2014-01-09 | 2018-03-20 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータSorin Group Italia S.r.l. | Blood processing unit having a heat exchanger core forming a modified flow path |
CN106029118B (en) | 2014-02-28 | 2018-10-02 | 索林集团意大利有限责任公司 | System for integrated arterial filter being arranged in oxygenator, is made increased priming volume minimize |
EP3131663A2 (en) | 2014-03-29 | 2017-02-22 | Princeton Trade and Technology Inc. | Blood processing cartridges and systems, and methods for extracorporeal blood therapies |
CN112807074A (en) | 2014-05-12 | 2021-05-18 | 弗吉尼亚暨州立大学知识产权公司 | Electroporation system |
EP3218087A1 (en) | 2014-11-12 | 2017-09-20 | Sorin Group Italia S.r.l. | Elastic protection tube for a hollow fibre blood processing apparatus |
US10694972B2 (en) | 2014-12-15 | 2020-06-30 | Virginia Tech Intellectual Properties, Inc. | Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment |
CN107635597B (en) | 2015-05-12 | 2020-11-27 | 索林集团意大利有限责任公司 | Blood gas exchanger with a restriction element or a plurality of restriction elements for reducing gas exchange |
US10426884B2 (en) | 2015-06-26 | 2019-10-01 | Novaflux Inc. | Cartridges and systems for outside-in flow in membrane-based therapies |
US10399040B2 (en) | 2015-09-24 | 2019-09-03 | Novaflux Inc. | Cartridges and systems for membrane-based therapies |
CN105343954B (en) * | 2015-09-25 | 2018-03-06 | 珠海健帆生物科技股份有限公司 | Compound apparatus for purifying blood and preparation method thereof |
TW201806631A (en) * | 2016-08-19 | 2018-03-01 | 施顯章 | Hemodialysis device |
EP3290100B1 (en) * | 2016-08-31 | 2020-08-19 | Gambro Lundia AB | Diffusion and/or filtration device |
US11607537B2 (en) | 2017-12-05 | 2023-03-21 | Virginia Tech Intellectual Properties, Inc. | Method for treating neurological disorders, including tumors, with electroporation |
US11311329B2 (en) | 2018-03-13 | 2022-04-26 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for immunotherapy based treatments using non-thermal ablation techniques |
US11925405B2 (en) | 2018-03-13 | 2024-03-12 | Virginia Tech Intellectual Properties, Inc. | Treatment planning system for immunotherapy enhancement via non-thermal ablation |
US11950835B2 (en) | 2019-06-28 | 2024-04-09 | Virginia Tech Intellectual Properties, Inc. | Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4202776A (en) | 1975-07-28 | 1980-05-13 | Nippon Zeon Co., Ltd. | Hollow-fiber permeability apparatus |
US4219426A (en) | 1976-03-19 | 1980-08-26 | Organon Teknika B.V. | Dialysis device |
JPS5322163A (en) | 1976-08-12 | 1978-03-01 | Nippon Zeon Co Ltd | Mass transfer apparatus of hollow fiber type |
DE2646358C2 (en) | 1976-10-14 | 1982-05-13 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg | Hollow fiber dialyzer |
FR2374932A1 (en) | 1976-12-24 | 1978-07-21 | Rhone Poulenc Ind | HOLLOW FIBER APPARATUS, USABLE IN PARTICULAR AS AN ARTIFICIAL KIDNEY |
US4201673A (en) | 1977-07-04 | 1980-05-06 | Terumo Corporation | Apparatus for dialysis of solution |
US4220535A (en) | 1978-08-04 | 1980-09-02 | Monsanto Company | Multi-zoned hollow fiber permeator |
DE2839937A1 (en) | 1978-09-14 | 1980-04-03 | Sigdell Jan Erik Dr | Hollow fibre dialyser - having hollow fibres laid in support grooves which can be wound round support core to give good blood distribution over fibres |
US4396510A (en) * | 1981-01-08 | 1983-08-02 | Bio-Med Corporation | Mass transfer device |
US4572724A (en) | 1984-04-12 | 1986-02-25 | Pall Corporation | Blood filter |
US4639353A (en) | 1984-04-24 | 1987-01-27 | Mitsubishi Rayon Co., Ltd. | Blood oxygenator using a hollow-fiber membrane |
US5192478A (en) | 1984-10-22 | 1993-03-09 | The Dow Chemical Company | Method of forming tubesheet for hollow fibers |
DE8527694U1 (en) | 1985-04-27 | 1987-02-19 | Akzo Gmbh, 5600 Wuppertal, De | |
DE3776562D1 (en) | 1986-09-12 | 1992-03-12 | Memtec Ltd | HOLLOW FIBER FILTER CARTRIDGE AND DISTRIBUTOR. |
SE454847B (en) | 1987-08-31 | 1988-06-06 | Gambro Dialysatoren | DEVICE FOR DIFFUSION AND / OR FILTERING AND PROCEDURE FOR MANUFACTURING THIS DEVICE |
JPH01148266A (en) | 1987-12-04 | 1989-06-09 | Terumo Corp | Blood filter |
JPH0696098B2 (en) | 1988-05-27 | 1994-11-30 | 株式会社クラレ | Hollow fiber type fluid treatment equipment |
US5139741A (en) | 1988-12-29 | 1992-08-18 | Terumo Kabushiki Kaisha | Blood processing apparatus of hollow fiber type |
JPH0614965B2 (en) | 1989-01-10 | 1994-03-02 | テルモ株式会社 | Oxygenator |
JPH0394928A (en) * | 1989-09-06 | 1991-04-19 | Mitsubishi Heavy Ind Ltd | Method for controlling synchronization between rotary perforating tools |
AU635414B2 (en) | 1990-04-18 | 1993-03-18 | Terumo Kabushiki Kaisha | Hollow fiber type liquid processing apparatus |
IT1240692B (en) | 1990-05-02 | 1993-12-17 | Dideco Spa | BLOOD FILTER IN MEDICAL EQUIPMENT |
FR2672513B1 (en) | 1991-02-13 | 1994-03-18 | Tech Sep | IMPROVED METHOD AND MODULE FOR FILTERING IN A LIQUID MEDIUM UNDER INSTANTANEOUS TANGENTIAL FLOW. |
US5264171A (en) | 1991-12-31 | 1993-11-23 | Hoechst Celanese Corporation | Method of making spiral-wound hollow fiber membrane fabric cartridges and modules having flow-directing baffles |
US5919369A (en) | 1992-02-06 | 1999-07-06 | Hemocleanse, Inc. | Hemofiltration and plasmafiltration devices and methods |
WO1994003266A1 (en) | 1992-08-03 | 1994-02-17 | Maloney James V Jr | Improved mass and thermal transfer means for use in heart lung machines, dialyzers, and other applications |
GB2276566A (en) | 1993-03-24 | 1994-10-05 | Saitekku Kabushiki Kaisha | Haemodialyser unit |
US5618425A (en) | 1993-04-30 | 1997-04-08 | Terumo Kabushiki Kaisha | Filtering apparatus with a pleated filtering element embedded in a filling material |
US5346621A (en) | 1993-05-19 | 1994-09-13 | Avecor Cardiovascular, Inc. | Hollow fiber blood oxygenator |
US5798041A (en) | 1995-09-06 | 1998-08-25 | Hemasure, Inc. | In-line liquid filtration device useable for blood, blood products or the like |
US5632894A (en) | 1994-06-24 | 1997-05-27 | Gish Biomedical, Inc. | Arterial blood filter with upwardly inclining delivery inlet conduit |
US5626759A (en) | 1994-08-01 | 1997-05-06 | Regents Of The University Of Colorado | Blood treatment device with moving membrane |
ES2142981T3 (en) | 1994-09-02 | 2000-05-01 | Terumo Corp | DIALIZER. |
US5500134A (en) | 1995-03-16 | 1996-03-19 | Dyna Flow, Inc. | Microfiltration system with swirling flow around filter medium |
US5525144A (en) | 1995-04-20 | 1996-06-11 | A/G Technology Corporation | Tangential flow filtering and separating |
US5651765A (en) | 1995-04-27 | 1997-07-29 | Avecor Cardiovascular Inc. | Blood filter with concentric pleats and method of use |
EP0765683B1 (en) | 1995-09-25 | 1998-07-01 | MEDOS Medizintechnik GmbH | Device for treating liquids, in particular blood |
WO1998022161A1 (en) | 1996-11-15 | 1998-05-28 | Scitec K.K. | Hollow fiber dialyzer |
EP0844015B1 (en) | 1996-11-21 | 2003-10-15 | Fresenius Medical Care Deutschland GmbH | Hollow fiber membrane separation device |
JP4115626B2 (en) | 1998-05-25 | 2008-07-09 | 旭化成クラレメディカル株式会社 | Method for producing hollow fiber membrane hemodialyzer |
US6113782A (en) | 1998-07-28 | 2000-09-05 | Terumo Cardiovascular Systems Corporation | Potting of tubular bundles in housing |
US6176904B1 (en) | 1999-07-02 | 2001-01-23 | Brij M. Gupta | Blood filter |
-
2001
- 2001-06-01 US US09/871,864 patent/US6623638B2/en not_active Expired - Lifetime
-
2002
- 2002-04-24 WO PCT/US2002/013043 patent/WO2002098490A1/en active Application Filing
- 2002-04-24 EP EP02776553A patent/EP1406685B1/en not_active Expired - Lifetime
- 2002-04-24 AT AT02776553T patent/ATE397946T1/en not_active IP Right Cessation
- 2002-04-24 DE DE60227076T patent/DE60227076D1/en not_active Expired - Lifetime
- 2002-04-24 MX MXPA03010988A patent/MXPA03010988A/en active IP Right Grant
- 2002-04-24 JP JP2003501527A patent/JP4036828B2/en not_active Expired - Fee Related
- 2002-04-29 AR ARP020101578A patent/AR033170A1/en not_active Application Discontinuation
- 2002-05-02 TW TW091109115A patent/TW553751B/en not_active IP Right Cessation
-
2007
- 2007-09-19 JP JP2007242902A patent/JP2008029857A/en active Pending
Non-Patent Citations (1)
Title |
---|
See references of WO02098490A1 * |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10448989B2 (en) | 2009-04-09 | 2019-10-22 | Virginia Tech Intellectual Properties, Inc. | High-frequency electroporation for cancer therapy |
US11707629B2 (en) | 2009-05-28 | 2023-07-25 | Angiodynamics, Inc. | System and method for synchronizing energy delivery to the cardiac rhythm |
US9895189B2 (en) | 2009-06-19 | 2018-02-20 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
US11931096B2 (en) | 2010-10-13 | 2024-03-19 | Angiodynamics, Inc. | System and method for electrically ablating tissue of a patient |
US9757196B2 (en) | 2011-09-28 | 2017-09-12 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
US11779395B2 (en) | 2011-09-28 | 2023-10-10 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
US9888956B2 (en) | 2013-01-22 | 2018-02-13 | Angiodynamics, Inc. | Integrated pump and generator device and method of use |
US11957405B2 (en) | 2013-06-13 | 2024-04-16 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
EP2954944A1 (en) | 2014-06-12 | 2015-12-16 | B. Braun Avitum AG | Dialyzer with a bundle of hollow fibres and method for producing such a hollow fibre |
DE102014108230A1 (en) | 2014-06-12 | 2015-12-17 | B. Braun Avitum Ag | Dialyzer with a bundle of hollow fibers and method for producing such a hollow fiber |
US11723710B2 (en) | 2016-11-17 | 2023-08-15 | Angiodynamics, Inc. | Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode |
Also Published As
Publication number | Publication date |
---|---|
US20030080047A1 (en) | 2003-05-01 |
TW553751B (en) | 2003-09-21 |
AR033170A1 (en) | 2003-12-03 |
US6623638B2 (en) | 2003-09-23 |
DE60227076D1 (en) | 2008-07-24 |
JP4036828B2 (en) | 2008-01-23 |
ATE397946T1 (en) | 2008-07-15 |
MXPA03010988A (en) | 2004-02-27 |
WO2002098490A1 (en) | 2002-12-12 |
JP2008029857A (en) | 2008-02-14 |
EP1406685B1 (en) | 2008-06-11 |
JP2004529723A (en) | 2004-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6623638B2 (en) | Hemodialyzer having improved dialysate perfusion | |
US20030075498A1 (en) | Hemodialyzer headers | |
US5730712A (en) | Extracorporeal blood treatment apparatus and method | |
US20230093577A1 (en) | Blood processing cartridges and systems, and methods for extracorporeal blood therapies | |
EP0176651B1 (en) | Heat exchanger and blood oxygenating device furnished therewith | |
JP4053421B2 (en) | Hemodiafiltration / blood filtration cartridge | |
EP2313125B1 (en) | Double fiber bundle dialyzer | |
US3728256A (en) | Crossflow capillary dialyzer | |
US4861485A (en) | Hemodiafiltration device | |
US20070119781A1 (en) | Apparatus and method for enhanced hemodialysis performance | |
US4038191A (en) | Manifold for ultra filtration machine | |
US5942112A (en) | Hollow fiber ultradialyzer apparatus | |
US10835868B2 (en) | Filter device, system and method for filtration of fluids | |
JP4328902B2 (en) | Online large-volume fluid replacement hemodialyzer | |
EP3167919B1 (en) | Blood purifier | |
JP3257999B2 (en) | Hollow fiber membrane dialyzer | |
Alex et al. | A Study on Hemodialyzer Membranes using Finite Element Analysis | |
CN219662452U (en) | Dialyser | |
EP0157941A1 (en) | Blood oxygenator using a hollow fiber membrane | |
JP3257998B2 (en) | Hollow fiber membrane dialyzer | |
EP3473327A1 (en) | Integrated fluid treatment device, and process using such device | |
JPS6129360A (en) | Artificial lung having dialytic function | |
JPS6137251A (en) | Heat exchanger built-in artificial lung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20031231 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SLEPICKA, JAMES, S. Inventor name: WATKINS, RANDOLPH, H. Inventor name: PRISCO, MICHAEL, R. |
|
17Q | First examination report despatched |
Effective date: 20061110 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REF | Corresponds to: |
Ref document number: 60227076 Country of ref document: DE Date of ref document: 20080724 Kind code of ref document: P |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
NLV1 | Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act | ||
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080922 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20081111 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
26N | No opposition filed |
Effective date: 20090312 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090430 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090430 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090424 Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090430 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080912 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20090424 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20080611 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 20130429 Year of fee payment: 12 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20130422 Year of fee payment: 12 |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: EUG |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140425 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140424 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 15 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20170427 Year of fee payment: 16 Ref country code: FR Payment date: 20170426 Year of fee payment: 16 Ref country code: GB Payment date: 20170427 Year of fee payment: 16 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 60227076 Country of ref document: DE |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20180424 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20181101 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180424 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180430 |