EP2049130A4 - Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid - Google Patents

Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid

Info

Publication number
EP2049130A4
EP2049130A4 EP07747120A EP07747120A EP2049130A4 EP 2049130 A4 EP2049130 A4 EP 2049130A4 EP 07747120 A EP07747120 A EP 07747120A EP 07747120 A EP07747120 A EP 07747120A EP 2049130 A4 EP2049130 A4 EP 2049130A4
Authority
EP
European Patent Office
Prior art keywords
cell culture
hyaluronic acid
soft tissue
derived cell
filler composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07747120A
Other languages
German (de)
French (fr)
Other versions
EP2049130A1 (en
Inventor
Bin Han
Jay Do Choi
Min Jung Nam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
S-BIOMEDICS Co Ltd
BIOMEDICS CO Ltd S
Original Assignee
S-BIOMEDICS Co Ltd
BIOMEDICS CO Ltd S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S-BIOMEDICS Co Ltd, BIOMEDICS CO Ltd S filed Critical S-BIOMEDICS Co Ltd
Publication of EP2049130A1 publication Critical patent/EP2049130A1/en
Publication of EP2049130A4 publication Critical patent/EP2049130A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656Adult fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0059Cosmetic or alloplastic implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP07747120A 2006-06-26 2007-06-26 Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid Withdrawn EP2049130A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020060057694A KR20070122315A (en) 2006-06-26 2006-06-26 Soft tissue filler composition comprising autologous dermal cell and hyaluronic acid
PCT/KR2007/003098 WO2008002063A1 (en) 2006-06-26 2007-06-26 Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid

Publications (2)

Publication Number Publication Date
EP2049130A1 EP2049130A1 (en) 2009-04-22
EP2049130A4 true EP2049130A4 (en) 2009-08-26

Family

ID=38845778

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07747120A Withdrawn EP2049130A4 (en) 2006-06-26 2007-06-26 Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid

Country Status (4)

Country Link
EP (1) EP2049130A4 (en)
KR (1) KR20070122315A (en)
AU (1) AU2007265862A1 (en)
WO (1) WO2008002063A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007040252A1 (en) 2006-09-11 2008-06-12 Gerlach, Jörg, Prof. Dr. Device for electronically flow-controlled distribution of tissue regenerating cell in sterile suspension across an area for further growth comprises electronically pressure/flow controlled spray head enabling controlled pump driven spraying
KR101421049B1 (en) * 2008-02-29 2014-07-21 (주)아모레퍼시픽 Cosmetic composition for lip-plumping and wrinkle-improvement of lips
ES2668398T3 (en) * 2008-07-02 2018-05-17 Allergan, Inc. Compositions and procedures for tissue filling and regeneration
US9173975B2 (en) 2009-04-24 2015-11-03 Ingeneron, Inc. Reparative cell delivery via hyaluronic acid vehicles
KR101145394B1 (en) * 2009-07-29 2012-05-15 주식회사 바이오랜드 Compositions for promoting stemness and proliferation of skin cells comprising Oligo-hyaluronic acid
WO2012000180A1 (en) * 2010-06-30 2012-01-05 Chen Jinxi Method for preparing dermis tissue cells aggregation and uses thereof
DE102011100450B8 (en) 2011-04-27 2013-10-17 Jörg Gerlach Apparatus for spraying cells, making the apparatus, method for spraying with the apparatus and a cell suspension sprayed with the apparatus
WO2014133339A1 (en) * 2013-02-28 2014-09-04 (주)아모레퍼시픽 Composition for maintaining efficacy of filler
AU2017283496B2 (en) 2016-06-14 2020-07-16 Renovacare Sciences Corp. Modular device for cell spraying
KR102459312B1 (en) * 2020-09-15 2022-10-26 주식회사 유나이티드엑티브 Fermentation method for the preparation of hyaluronic acid with hydrophobic properties
KR102358306B1 (en) 2020-10-08 2022-02-07 김예주 Injectable composition for neck wrinkles
CN113456574A (en) * 2021-07-09 2021-10-01 上海鄄飞健康管理咨询有限公司 Nutrient solution with neck anti-aging function and use method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000037124A1 (en) * 1998-12-21 2000-06-29 Fidia Advanced Biopolymers, S.R.L. Injectable hyaluronic acid derivative with pharmaceuticals/cells
US20020197241A1 (en) * 1998-05-22 2002-12-26 Isolagen Technologies, Inc. A Delaware Corporation Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
EP1358857A1 (en) * 1995-07-28 2003-11-05 Isolagen International S.A. The use of autologous dermal fibroblasts for the repair of skin and soft tissue defects
WO2006125991A1 (en) * 2005-05-26 2006-11-30 Intercytex Limited Tissue repair using allogenic dermal fibroblasts
WO2007139525A2 (en) * 2006-05-31 2007-12-06 Kemal Tunc Tiryaki A method and a tissue material for use in the treatment of the skin defects and aging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965125A (en) * 1995-10-25 1999-10-12 Transkaryotic Therapies, Inc. Hybrid matrix implants and explants
EP1056413A4 (en) * 1998-02-27 2003-08-20 Bioelastics Res Ltd Injectable implants for tissue augmentation and restoration
US8394371B2 (en) * 2002-02-11 2013-03-12 Neocutis Sa Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358857A1 (en) * 1995-07-28 2003-11-05 Isolagen International S.A. The use of autologous dermal fibroblasts for the repair of skin and soft tissue defects
US20020197241A1 (en) * 1998-05-22 2002-12-26 Isolagen Technologies, Inc. A Delaware Corporation Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
WO2000037124A1 (en) * 1998-12-21 2000-06-29 Fidia Advanced Biopolymers, S.R.L. Injectable hyaluronic acid derivative with pharmaceuticals/cells
WO2006125991A1 (en) * 2005-05-26 2006-11-30 Intercytex Limited Tissue repair using allogenic dermal fibroblasts
WO2007139525A2 (en) * 2006-05-31 2007-12-06 Kemal Tunc Tiryaki A method and a tissue material for use in the treatment of the skin defects and aging

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"IBMS-ECTS 2005 Abstracts", BONE, PERGAMON PRESS., OXFORD, GB, vol. 36, 1 January 2005 (2005-01-01), pages S103 - S479, XP025396852, ISSN: 8756-3282, [retrieved on 20050101] *
See also references of WO2008002063A1 *
YOON EUL-SIK ET AL: "Advantages of the Presence of Living Dermal Fibroblasts Within Restylane for Soft Tissue Augmentation", ANNALS OF PLASTIC SURGERY, LITTLE, BROWN AND CO, US, vol. 51, no. 6, 1 December 2003 (2003-12-01), pages 587 - 592, XP008093679, ISSN: 0148-7043 *

Also Published As

Publication number Publication date
AU2007265862A1 (en) 2008-01-03
EP2049130A1 (en) 2009-04-22
KR20070122315A (en) 2007-12-31
WO2008002063A1 (en) 2008-01-03

Similar Documents

Publication Publication Date Title
EP2049130A4 (en) Soft tissue filler composition comprising autologous dermis-derived cell culture product and hyaluronic acid
HK1196034A1 (en) Cryopreservative composition for cell and tissue
EP2066785A4 (en) Bacteria cultures and compositions comprising bacteria cultures
IL194438A (en) Diarylthiohydantoin compounds, pharmaceutical compositions comprising them, methods for their synthesis and in vitro methods for contacting them with mammalian cells
IL221384A0 (en) Improving il-15 and il-15r-alpha for expression in mammalian cells
EP2360188A4 (en) Hyaluronic acid derivative and pharmaceutical composition thereof
WO2011082038A3 (en) Improved reprogramming compositions
IL198008A0 (en) Methods and compositions for treatment of bone defects with placental cell populations
EP2155235A4 (en) Oxygen-generating compositions for enhancing cell and tissue survival in vivo
HRP20130812T1 (en) Methods and compositions for treatment of bone defects with placental cell populations
HK1145652A1 (en) Materials and methods for delivering compositions to selected tissues
ZA201200727B (en) Modified hyaluronic acid polymer compositions and related methods
IL217552A0 (en) Methods and compositions for in vitro and in vivo chondrogenesis
SG10202109176RA (en) Compositions and methods useful for culturing differentiable cells
EP1948810A4 (en) Composition and method for efficient delivery of nucleic acids to cells using chitosan
HK1146220A1 (en) Gel technology suitable for use in cosmetic compositions
EP2013357A4 (en) Expression of o-glycosylated therapeutic proteins in prokaryotic microorganisms
EP2210608A4 (en) Pharmaceutical composition containing human mesenchymal stem cell
WO2008026928A3 (en) Repair of cartilage tissue using a matrix gel containing chondrocytes
EP1980274A4 (en) Corneal endothelial preparation which enables cells to grow in vivo
AU2008350785A8 (en) Immunogenic peptides and their use in transplantation
EP2448957A4 (en) Methods and compositions for affecting the differentiation of clostridia in culture
EP2344625A4 (en) Methods and compositions for high-resolution micropatterning for cell culture
IL194667A (en) Compositions comprising mismatched allogeneic cells and uses thereof in treating infection
EP2034954A4 (en) Non-viral compositions and methods for transfecting gut cells in vivo

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20090123

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

A4 Supplementary search report drawn up and despatched

Effective date: 20090729

17Q First examination report despatched

Effective date: 20091110

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20120108