EP2603083A4 - Bismuth-thiols as antiseptics for agricultural, industrial and other uses - Google Patents

Bismuth-thiols as antiseptics for agricultural, industrial and other uses

Info

Publication number
EP2603083A4
EP2603083A4 EP11817067.9A EP11817067A EP2603083A4 EP 2603083 A4 EP2603083 A4 EP 2603083A4 EP 11817067 A EP11817067 A EP 11817067A EP 2603083 A4 EP2603083 A4 EP 2603083A4
Authority
EP
European Patent Office
Prior art keywords
antiseptics
thiols
bismuth
agricultural
industrial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11817067.9A
Other languages
German (de)
French (fr)
Other versions
EP2603083A2 (en
Inventor
Brett Hugh James Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbion Corp
Original Assignee
Microbion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2011/023549 external-priority patent/WO2011097347A2/en
Application filed by Microbion Corp filed Critical Microbion Corp
Publication of EP2603083A2 publication Critical patent/EP2603083A2/en
Publication of EP2603083A4 publication Critical patent/EP2603083A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/29—Antimony or bismuth compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
EP11817067.9A 2010-08-12 2011-08-11 Bismuth-thiols as antiseptics for agricultural, industrial and other uses Withdrawn EP2603083A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37318810P 2010-08-12 2010-08-12
PCT/US2011/023549 WO2011097347A2 (en) 2010-02-03 2011-02-03 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
PCT/US2011/047490 WO2012021754A2 (en) 2010-08-12 2011-08-11 Bismuth-thiols as antiseptics for agricultural, industrial and other uses

Publications (2)

Publication Number Publication Date
EP2603083A2 EP2603083A2 (en) 2013-06-19
EP2603083A4 true EP2603083A4 (en) 2014-10-22

Family

ID=44356067

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11817067.9A Withdrawn EP2603083A4 (en) 2010-08-12 2011-08-11 Bismuth-thiols as antiseptics for agricultural, industrial and other uses

Country Status (16)

Country Link
EP (1) EP2603083A4 (en)
JP (7) JP2013535506A (en)
KR (6) KR102074444B1 (en)
CN (2) CN103096720B (en)
AU (3) AU2011289338B2 (en)
BR (2) BR112012019286A2 (en)
CA (1) CA2807993C (en)
CL (2) CL2013000430A1 (en)
IL (3) IL224684A (en)
MX (4) MX371047B (en)
NZ (1) NZ606634A (en)
PH (1) PH12016502498A1 (en)
RU (2) RU2013110493A (en)
SG (3) SG10201506131RA (en)
UA (1) UA113616C2 (en)
WO (1) WO2012021754A2 (en)

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US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
JP5674684B2 (en) 2009-02-03 2015-02-25 マイクロビオン コーポレーション Bismuth-thiol as a disinfectant for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
KR102074444B1 (en) * 2010-02-03 2020-02-06 마이크로비온 코포레이션 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
ES2647499T3 (en) * 2013-03-18 2017-12-21 Theranovis Gmbh & Co. Kg Composition for oral care
RU2525200C1 (en) * 2013-04-09 2014-08-10 Алексей Георгиевич Бородкин Agent for protection and repair of wound of trees
KR101703732B1 (en) * 2013-11-07 2017-02-07 (주)아모레퍼시픽 Anti-inflammatory composition containing enzymated camellia japonica seed oil
WO2017145142A1 (en) 2016-02-25 2017-08-31 Nobio Ltd. Micro and nanoparticulate compositions comprising anti-microbially active groups
BR112020004156A2 (en) 2017-08-30 2020-09-08 Nobio Ltd. antimicrobial particles and methods of applying them
CN107950536A (en) * 2017-12-04 2018-04-24 刘志伟 A kind of bactericidal composition containing Bravo
CN108839186B (en) * 2018-05-15 2021-02-26 阜南县金威工艺品有限公司 Mildew-proof treatment method for mulberry twig woven product
EP3829299A4 (en) 2018-07-31 2022-04-13 Microbion Corporation Bismuth-thiol compositions and methods for treating wounds
CN112804878A (en) 2018-07-31 2021-05-14 微生物公司 Bismuth-thiol compositions and methods of use
KR101990253B1 (en) * 2018-11-22 2019-06-17 하봉호 Container type mushroom growing apparatus
CN109997856B (en) * 2019-04-15 2020-11-03 广西大学 Composition of small molecular compound and application thereof
KR102126721B1 (en) * 2019-07-16 2020-06-25 (주)인트론바이오테크놀로지 Novel Enterobacter aerogenes bacteriophage Ent-AEP-1 and its use for preventing proliferation of Enterobacter aerogenes and Enterobacter cloacae
JP7458622B2 (en) 2019-09-18 2024-04-01 学校法人東京農業大学 Substances that reduce the resistance of antibiotic-resistant microorganisms and methods for reducing the resistance of antibiotic-resistant microorganisms
US11479655B2 (en) * 2020-01-15 2022-10-25 The Boeing Company Compositions for use with polysulfide sealants and related methods
KR102197719B1 (en) 2020-05-07 2021-01-04 곽태진 Cuttlefish breeding system
CN111856546B (en) * 2020-06-23 2022-07-29 中国辐射防护研究院 Sample preparation method for radiochemical analysis of Cs-137 in marine organism ash
CN113969300A (en) * 2020-07-23 2022-01-25 启迪禾美生物科技(嘉兴)有限公司 Eucalyptus leaf composite active extract process and antibacterial application thereof
CN112640907B (en) * 2021-01-19 2021-11-16 西南大学 Novel application of lipoic acid in inhibiting plant fungal pathogenic bacteria and method for preventing and treating citrus fruit postharvest fungal diseases
KR102431000B1 (en) * 2021-07-22 2022-08-11 농업회사법인 주식회사 아그로비즈 Composition for an autoimmune builder of plants containing aspirin and benzothiazole, and method of using the same
EP4310192A1 (en) * 2022-07-21 2024-01-24 C4Diagnostics Method of determining the existence and/or degree of resistance of microorganisms to antimicrobial agents
CN115323778B (en) * 2022-08-16 2023-07-18 汕头市润丰纺织科技实业有限公司 Chitosan-I type collagen amino acid composite antibacterial finishing liquid, preparation method thereof and antibacterial fabric
TR2022012983A2 (en) * 2022-08-17 2022-09-21 Marmara Ueniv Strateji Gelis Dai Bsk Muhasebe Birimi A BIOCOMPATIBLE PRODUCT WITH REPRESENTATIVE AND THERAPEUTIC PROPERTIES FOR BONE DISORDERS AND/OR FRACTURES AND A METHOD FOR OBTAINING THE SUBJECT PRODUCT
CN115532295B (en) * 2022-09-27 2023-07-25 苏州大学 Application of nanomaterial containing Zn-N-C active center in removal of bacterial biofilm
KR102644907B1 (en) * 2023-12-01 2024-03-07 (주)신용이엔씨 Eco-friendly grouting composition for ground reinforcement and method of manufacturing the same

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US5928671A (en) * 1995-04-25 1999-07-27 Winthrop University Hospital Method and composition for inhibiting bacteria
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
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AU2003204105B2 (en) * 1997-10-28 2005-11-17 Winthrop-University Hospital Metal/Thiol Biocides
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US5928671A (en) * 1995-04-25 1999-07-27 Winthrop University Hospital Method and composition for inhibiting bacteria
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
AU2003204105B2 (en) * 1997-10-28 2005-11-17 Winthrop-University Hospital Metal/Thiol Biocides
US20020197282A1 (en) * 1999-02-23 2002-12-26 Mohseni Saeed H. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
US20020136780A1 (en) * 2001-01-22 2002-09-26 Batarseh Kareem I. Microbicidal composition containing potassium sodium tartrate
JP2004137241A (en) * 2002-10-21 2004-05-13 Catalysts & Chem Ind Co Ltd Antibacterial/mildew-proofing/algicidal composition
WO2008092011A2 (en) * 2007-01-24 2008-07-31 Cook Incorporated Biofilm-inhibiting medical products
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Title
DATABASE WPI Derwent World Patents Index; AN 2004-369133, XP002728841 *
DOMENICO P ET AL: "Enhancement of Bismuth Antibacterila Activity with Lipophilic Thiol Chelators", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 41, no. 8, 1 August 1997 (1997-08-01), pages 1697 - 1703, XP002262341, ISSN: 0066-4804 *
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See also references of WO2012021754A2 *
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