EP2766087A4 - Non-regular electrical stimulation patterns for treating neurological disorders - Google Patents

Non-regular electrical stimulation patterns for treating neurological disorders

Info

Publication number: EP2766087A4
Authority: EP; European Patent Office
Prior art keywords: electrical stimulation; neurological disorders; treating neurological; stimulation patterns; regular electrical
Prior art date: 2011-10-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP12839657.9A

Other languages

German (de)

French (fr)

Other versions

EP2766087A2 (en

Inventor

Warren M Grill

David T Brocker

Merill J Birdno

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Duke University

Original Assignee

Duke University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-11

Filing date

2012-10-11

Publication date

2015-05-06

2012-10-11 Application filed by Duke University filed Critical Duke University

2012-10-11 Priority to EP20175204.5A priority Critical patent/EP3718596B1/en

2012-10-11 Priority to EP18167953.1A priority patent/EP3372274B1/en

2014-08-20 Publication of EP2766087A2 publication Critical patent/EP2766087A2/en

2015-05-06 Publication of EP2766087A4 publication Critical patent/EP2766087A4/en

Status Ceased legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
- A61N1/36178—Burst or pulse train parameters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0534—Electrodes for deep brain stimulation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36189—Control systems using modulation techniques
- A61N1/36196—Frequency modulation

Landscapes

Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Developmental Disabilities (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Electrotherapy Devices (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP12839657.9A 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders Ceased EP2766087A4 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
EP20175204.5A EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161545791P	2011-10-11	2011-10-11
US201161558871P	2011-11-11	2011-11-11
PCT/US2012/059787 WO2013055940A2 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP18167953.1A Division EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A Division EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Publications (2)

Publication Number	Publication Date
EP2766087A2 EP2766087A2 (en)	2014-08-20
EP2766087A4 true EP2766087A4 (en)	2015-05-06

Family

ID=48082746

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
EP12839657.9A Ceased EP2766087A4 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Country Status (5)

Country	Link
EP (3)	EP2766087A4 (en)
CN (2)	CN103889503B (en)
AU (4)	AU2012322739A1 (en)
CA (2)	CA3169207A1 (en)
WO (1)	WO2013055940A2 (en)

Families Citing this family (30)

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Publication number	Priority date	Publication date	Assignee	Title
CN102238978B (en)	2008-10-03	2014-09-24	杜克大学	Non-regular electrical stimulation patterns for treating neurological disorders
US8798755B2 (en)	2008-10-03	2014-08-05	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US8923981B2 (en)	2008-10-03	2014-12-30	Duke University	Non-regular electrical stimulation patterns designed with a cost function for treating neurological disorders
US11013924B2 (en)	2008-10-03	2021-05-25	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
CA2800889C (en)	2010-05-27	2018-12-04	Ndi Medical, Llc	Waveform shapes for treating neurological disorders optimized for energy efficiency
US9821159B2 (en)	2010-11-16	2017-11-21	The Board Of Trustees Of The Leland Stanford Junior University	Stimulation devices and methods
EP2640461B1 (en)	2010-11-16	2019-06-19	The Board Of Trustees Of The Leland Stanford Junior University	Systems for treatment of dry eye
US9717627B2 (en)	2013-03-12	2017-08-01	Oculeve, Inc.	Implant delivery devices, systems, and methods
CN105307718B (en)	2013-04-19	2018-05-11	奥库利维公司	Nose stimulating apparatus and method
EP2999515A4 (en) *	2013-05-22	2016-10-05	Deep Brain Innovations LLC	Deep brain stimulator and method of use
WO2015100306A1 (en)	2013-12-23	2015-07-02	Deep Brain Innovations LLC	Programming systems for deep brain stimulator system
EP3689338A1 (en)	2014-02-25	2020-08-05	Oculeve, Inc.	Polymer formulations for nasolacrimal stimulation
DK3171928T3 (en)	2014-07-25	2020-05-18	Oculeve Inc	STIMULATION PATTERNS FOR TREATMENT OF DRY EYES
AU2015335776B2 (en)	2014-10-22	2020-09-03	Oculeve, Inc.	Stimulation devices and methods for treating dry eye
US9764150B2 (en)	2014-10-22	2017-09-19	Oculeve, Inc.	Contact lens for increasing tear production
WO2016065213A1 (en)	2014-10-22	2016-04-28	Oculeve, Inc.	Implantable nasal stimulator systems and methods
DE102014117429A1 (en) *	2014-11-27	2016-06-02	Forschungszentrum Jülich GmbH	Apparatus and method for effective invasive neurostimulation by means of varying stimulus sequences
WO2016182894A1 (en) *	2015-05-08	2016-11-17	Duke University	Systems and methods for spinal cord stimulation
CN107921255B (en)	2015-07-30	2021-02-26	波士顿科学神经调制公司	User interface for custom-patterned electrical stimulation
US10603482B2 (en)	2015-09-23	2020-03-31	Cala Health, Inc.	Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
EP3362139B1 (en)	2015-10-15	2020-07-29	Boston Scientific Neuromodulation Corporation	User interface for neurostimulation waveform composition
US10391313B2 (en)	2015-12-04	2019-08-27	Boston Scientific Neuromodulation Corporation	Systems and methods for the development of therapy paradigms for neurological treatments
US10426958B2 (en)	2015-12-04	2019-10-01	Oculeve, Inc.	Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
AU2017211048B2 (en)	2016-01-21	2022-03-10	Cala Health, Inc.	Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10252048B2 (en)	2016-02-19	2019-04-09	Oculeve, Inc.	Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
CA3022683A1 (en)	2016-05-02	2017-11-09	Oculeve, Inc.	Intranasal stimulation for treatment of meibomian gland disease and blepharitis
JP2020500609A (en)	2016-12-02	2020-01-16	オキュリーブ，インコーポレイテッド	Apparatus and method for dry eye prediction and treatment recommendations
US11857778B2 (en)	2018-01-17	2024-01-02	Cala Health, Inc.	Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11890468B1 (en)	2019-10-03	2024-02-06	Cala Health, Inc.	Neurostimulation systems with event pattern detection and classification
US20230064864A1 (en) *	2020-01-15	2023-03-02	Carnegie Mellon University	Neuromodulation Using Electrical Stimulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1003839B (en) *	1986-04-24	1989-04-12	顾涵森	Apparatus and method for generating vital information signal
US6366813B1 (en) *	1998-08-05	2002-04-02	Dilorenzo Daniel J.	Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7010351B2 (en) *	2000-07-13	2006-03-07	Northstar Neuroscience, Inc.	Methods and apparatus for effectuating a lasting change in a neural-function of a patient
DE10318071A1 (en) *	2003-04-17	2004-11-25	Forschungszentrum Jülich GmbH	Device for desynchronizing neuronal brain activity
CN101262904A (en) *	2005-09-15	2008-09-10	皇家飞利浦电子股份有限公司	Apparatus and method for electrostimulation/sensing in vivo

2012
- 2012-10-11 CA CA3169207A patent/CA3169207A1/en active Pending
- 2012-10-11 CA CA2846639A patent/CA2846639C/en active Active
- 2012-10-11 WO PCT/US2012/059787 patent/WO2013055940A2/en active Application Filing
- 2012-10-11 EP EP12839657.9A patent/EP2766087A4/en not_active Ceased
- 2012-10-11 CN CN201280049892.3A patent/CN103889503B/en active Active
- 2012-10-11 EP EP20175204.5A patent/EP3718596B1/en active Active
- 2012-10-11 CN CN201710058910.9A patent/CN106955417B/en active Active
- 2012-10-11 AU AU2012322739A patent/AU2012322739A1/en not_active Abandoned
- 2012-10-11 EP EP18167953.1A patent/EP3372274B1/en active Active
2017
- 2017-05-08 AU AU2017203037A patent/AU2017203037B2/en active Active
2019
- 2019-07-15 AU AU2019205970A patent/AU2019205970B2/en active Active
2021
- 2021-05-04 AU AU2021202778A patent/AU2021202778A1/en not_active Abandoned

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

Also Published As

Publication number	Publication date
AU2017203037B2 (en)	2019-04-18
AU2019205970B2 (en)	2021-02-04
CN106955417A (en)	2017-07-18
CN106955417B (en)	2021-08-20
EP3372274B1 (en)	2020-06-24
AU2017203037A1 (en)	2017-06-01
CN103889503B (en)	2017-03-08
EP3718596B1 (en)	2023-06-28
CN103889503A (en)	2014-06-25
EP3718596A1 (en)	2020-10-07
WO2013055940A2 (en)	2013-04-18
WO2013055940A3 (en)	2014-05-30
CA2846639C (en)	2022-10-18
AU2012322739A1 (en)	2014-03-13
AU2019205970A1 (en)	2019-08-01
EP2766087A2 (en)	2014-08-20
CA3169207A1 (en)	2013-04-18
AU2021202778A1 (en)	2021-05-27
EP3372274A1 (en)	2018-09-12
CA2846639A1 (en)	2013-04-18

Legal Events

Date	Code	Title	Description
2014-07-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2014-08-20	17P	Request for examination filed	Effective date: 20140327
2014-08-20	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-05-06	A4	Supplementary search report drawn up and despatched	Effective date: 20150407
2015-05-06	DAX	Request for extension of the european patent (deleted)
2015-05-06	RIC1	Information provided on ipc code assigned before grant	Ipc: A61N 1/00 20060101AFI20150330BHEP Ipc: A61N 1/36 20060101ALI20150330BHEP Ipc: A61N 1/05 20060101ALI20150330BHEP
2016-03-16	17Q	First examination report despatched	Effective date: 20160215
2018-02-26	REG	Reference to a national code	Ref country code: DE Ref legal event code: R003
2018-06-01	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2018-07-04	18R	Application refused	Effective date: 20180226

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