EP2822646A4 - Modulating afferent signals to treat medical conditions - Google Patents
Modulating afferent signals to treat medical conditionsInfo
- Publication number
- EP2822646A4 EP2822646A4 EP13757567.6A EP13757567A EP2822646A4 EP 2822646 A4 EP2822646 A4 EP 2822646A4 EP 13757567 A EP13757567 A EP 13757567A EP 2822646 A4 EP2822646 A4 EP 2822646A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- medical conditions
- treat medical
- afferent signals
- modulating
- modulating afferent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/3611—Respiration control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
- A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Electrotherapy Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261609169P | 2012-03-09 | 2012-03-09 | |
PCT/US2013/029930 WO2013134667A1 (en) | 2012-03-09 | 2013-03-08 | Modulating afferent signals to treat medical conditions |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2822646A1 EP2822646A1 (en) | 2015-01-14 |
EP2822646A4 true EP2822646A4 (en) | 2016-04-27 |
EP2822646B1 EP2822646B1 (en) | 2023-10-18 |
Family
ID=49117391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13757567.6A Active EP2822646B1 (en) | 2012-03-09 | 2013-03-08 | Modulating afferent signals to treat medical conditions |
Country Status (3)
Country | Link |
---|---|
US (3) | US10300281B2 (en) |
EP (1) | EP2822646B1 (en) |
WO (1) | WO2013134667A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013134667A1 (en) | 2012-03-09 | 2013-09-12 | Mayo Foundation For Medical Education And Research | Modulating afferent signals to treat medical conditions |
WO2017146659A1 (en) * | 2016-02-24 | 2017-08-31 | Cakmak Yusuf Ozgur | A system for decreasing the blood pressure |
KR102068290B1 (en) * | 2017-02-10 | 2020-01-20 | 서울대학교산학협력단 | Pharmaceutical composition for the prevention or treatment of afferent nerve diseases comprising Tentonin 3 and use thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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US20030216792A1 (en) * | 2002-04-08 | 2003-11-20 | Levin Howard R. | Renal nerve stimulation method and apparatus for treatment of patients |
WO2006022790A1 (en) * | 2002-04-08 | 2006-03-02 | Ardian, Inc. | Methods and devices for renal nerve blocking |
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US3991770A (en) | 1974-01-24 | 1976-11-16 | Leveen Harry H | Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation |
US5811463A (en) | 1993-10-06 | 1998-09-22 | University Of British Columbia | Compositions and method for relaxing smooth muscles |
US5527307A (en) | 1994-04-01 | 1996-06-18 | Minimed Inc. | Implantable medication infusion pump with discharge side port |
US6558351B1 (en) | 1999-06-03 | 2003-05-06 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
ATE499988T1 (en) | 2000-03-02 | 2011-03-15 | Microchips Inc | MICROMECHANICAL DEVICES AND METHODS FOR STORAGE AND SELECTIVE EXPOSURE OF CHEMICALS |
DE60116520T2 (en) | 2000-10-10 | 2006-08-31 | Microchips, Inc., Bedford | MICROCHIP RESERVOIR DEVICES WITH WIRELESS TRANSMISSION OF ENERGY AND DATA |
US6928320B2 (en) | 2001-05-17 | 2005-08-09 | Medtronic, Inc. | Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated |
US20060116736A1 (en) * | 2001-07-23 | 2006-06-01 | Dilorenzo Daniel J | Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of obesity |
US7204823B2 (en) | 2001-12-19 | 2007-04-17 | Medtronic Minimed, Inc. | Medication delivery system and monitor |
US20110207758A1 (en) | 2003-04-08 | 2011-08-25 | Medtronic Vascular, Inc. | Methods for Therapeutic Renal Denervation |
US8145316B2 (en) * | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US20050065553A1 (en) * | 2003-06-13 | 2005-03-24 | Omry Ben Ezra | Applications of vagal stimulation |
US7292890B2 (en) | 2002-06-20 | 2007-11-06 | Advanced Bionics Corporation | Vagus nerve stimulation via unidirectional propagation of action potentials |
US20040172084A1 (en) | 2003-02-03 | 2004-09-02 | Knudson Mark B. | Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) |
US7613515B2 (en) | 2003-02-03 | 2009-11-03 | Enteromedics Inc. | High frequency vagal blockage therapy |
US20050075702A1 (en) * | 2003-10-01 | 2005-04-07 | Medtronic, Inc. | Device and method for inhibiting release of pro-inflammatory mediator |
US7232435B2 (en) | 2004-02-06 | 2007-06-19 | Medtronic, Inc. | Delivery of a sympatholytic cardiovascular agent to the central nervous system to counter heart failure and pathologies associated with heart failure |
CN101010724B (en) | 2004-08-27 | 2011-05-25 | 松下电器产业株式会社 | Audio encoder |
EP1904160B1 (en) | 2005-06-09 | 2011-12-21 | Medtronic, Inc. | Peripheral nerve field stimulation and spinal cord stimulation |
US20070073354A1 (en) | 2005-09-26 | 2007-03-29 | Knudson Mark B | Neural blocking therapy |
US20070196510A1 (en) | 2006-02-17 | 2007-08-23 | Gerber Michael J | Method for treating resistant hypertension |
AU2007217100A1 (en) | 2006-02-17 | 2007-08-30 | Gilead Colorado, Inc. | Antihypertensive therapy |
US20070275035A1 (en) | 2006-05-24 | 2007-11-29 | Microchips, Inc. | Minimally Invasive Medical Implant Devices for Controlled Drug Delivery |
US8768469B2 (en) * | 2008-08-08 | 2014-07-01 | Enteromedics Inc. | Systems for regulation of blood pressure and heart rate |
US20100114244A1 (en) | 2008-10-31 | 2010-05-06 | Medtronic, Inc. | Electrical renal autonomic blockade |
US9370654B2 (en) | 2009-01-27 | 2016-06-21 | Medtronic, Inc. | High frequency stimulation to block laryngeal stimulation during vagal nerve stimulation |
US8399443B2 (en) | 2009-04-22 | 2013-03-19 | Mercator Medsystems, Inc. | Treatment of hypertension by renal vascular delivery of guanethidine |
US20140074076A1 (en) | 2009-10-12 | 2014-03-13 | Kona Medical, Inc. | Non-invasive autonomic nervous system modulation |
US8825164B2 (en) | 2010-06-11 | 2014-09-02 | Enteromedics Inc. | Neural modulation devices and methods |
US9782592B2 (en) | 2010-07-15 | 2017-10-10 | Boston Scientific Neuromodulation Corporation | Energy efficient high frequency nerve blocking technique |
EP4137199A1 (en) | 2010-11-17 | 2023-02-22 | Medtronic Ireland Manufacturing Unlimited Company | Systems for therapeutic renal neuromodulation for treating dyspnea |
US20130261368A1 (en) | 2011-09-23 | 2013-10-03 | Alan N. Schwartz | Non-invasive and minimally invasive and tightly targeted minimally invasive therapy methods and devices for parathyroid treatment |
CN104254367A (en) | 2012-03-07 | 2014-12-31 | 美敦力阿迪安卢森堡有限公司 | Selective modulation of renal nerves |
WO2013134121A2 (en) | 2012-03-07 | 2013-09-12 | Enteromedics Inc. | Devices for regulation of blood pressure and heart rate |
WO2013134667A1 (en) | 2012-03-09 | 2013-09-12 | Mayo Foundation For Medical Education And Research | Modulating afferent signals to treat medical conditions |
US20150080926A1 (en) | 2012-04-27 | 2015-03-19 | Medtronic Ardian Luxembourg S.A.R.L. | Ultrasound apparatuses, systems, and methods for renal neuromodulation |
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US20170112564A1 (en) | 2014-04-01 | 2017-04-27 | Mayo Foundation For Medical Education And Research | Methods and materials for treating hypertension |
WO2015153775A1 (en) | 2014-04-01 | 2015-10-08 | Mayo Foundation For Medical Education And Research | Methods and materials for treating elevated sympathetic nerve activity conditions |
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WO2015164658A1 (en) | 2014-04-24 | 2015-10-29 | Sympara Medical, Inc. | Methods and devices for treating hypertension |
US9393384B1 (en) | 2015-08-17 | 2016-07-19 | Tufts Medical Center, Inc. | Systems and methods for treating acute and chronic heart failure |
-
2013
- 2013-03-08 WO PCT/US2013/029930 patent/WO2013134667A1/en active Application Filing
- 2013-03-08 EP EP13757567.6A patent/EP2822646B1/en active Active
- 2013-03-08 US US14/383,964 patent/US10300281B2/en active Active
-
2019
- 2019-05-21 US US16/418,307 patent/US11207519B2/en active Active
-
2021
- 2021-11-19 US US17/531,379 patent/US20220062637A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030216792A1 (en) * | 2002-04-08 | 2003-11-20 | Levin Howard R. | Renal nerve stimulation method and apparatus for treatment of patients |
WO2006022790A1 (en) * | 2002-04-08 | 2006-03-02 | Ardian, Inc. | Methods and devices for renal nerve blocking |
Non-Patent Citations (1)
Title |
---|
ANONYMOUS: "Classes of Heart Failure", 1 January 2015 (2015-01-01), XP002748697, Retrieved from the Internet <URL:http://www.heart.org/HEARTORG/Conditions/HeartFailure/AboutHeartFailure/Classes-of-Heart-Failure_UCM_306328_Article.jsp#.Vi5rdqNwbok> [retrieved on 20151026] * |
Also Published As
Publication number | Publication date |
---|---|
EP2822646A1 (en) | 2015-01-14 |
US20220062637A1 (en) | 2022-03-03 |
US10300281B2 (en) | 2019-05-28 |
US20150057313A1 (en) | 2015-02-26 |
US20190269923A1 (en) | 2019-09-05 |
US11207519B2 (en) | 2021-12-28 |
EP2822646B1 (en) | 2023-10-18 |
WO2013134667A1 (en) | 2013-09-12 |
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