EP2976044A4 - Compositions and methods for dental tissue regeneration - Google Patents

Compositions and methods for dental tissue regeneration

Info

Publication number
EP2976044A4
EP2976044A4 EP14771102.2A EP14771102A EP2976044A4 EP 2976044 A4 EP2976044 A4 EP 2976044A4 EP 14771102 A EP14771102 A EP 14771102A EP 2976044 A4 EP2976044 A4 EP 2976044A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
tissue regeneration
dental tissue
dental
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14771102.2A
Other languages
German (de)
French (fr)
Other versions
EP2976044A1 (en
Inventor
Jeremy J Mao
Ying Zheng
Guoming Sun
Songlin Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University of New York
Original Assignee
Columbia University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University of New York filed Critical Columbia University of New York
Publication of EP2976044A1 publication Critical patent/EP2976044A1/en
Publication of EP2976044A4 publication Critical patent/EP2976044A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
EP14771102.2A 2013-03-21 2014-03-21 Compositions and methods for dental tissue regeneration Withdrawn EP2976044A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361804138P 2013-03-21 2013-03-21
US201361831595P 2013-06-05 2013-06-05
PCT/US2014/031512 WO2014153548A1 (en) 2013-03-21 2014-03-21 Compositions and methods for dental tissue regeneration

Publications (2)

Publication Number Publication Date
EP2976044A1 EP2976044A1 (en) 2016-01-27
EP2976044A4 true EP2976044A4 (en) 2016-11-23

Family

ID=51581532

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14771102.2A Withdrawn EP2976044A4 (en) 2013-03-21 2014-03-21 Compositions and methods for dental tissue regeneration

Country Status (3)

Country Link
EP (1) EP2976044A4 (en)
CN (1) CN105228557A (en)
WO (1) WO2014153548A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2534315B (en) 2013-10-02 2020-08-05 Univ Leland Stanford Junior WNT compositions and methods for purification
US10512668B2 (en) 2014-12-29 2019-12-24 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production
CN104548212B (en) * 2014-12-31 2018-05-11 新科沃再生医学（苏州）有限公司 One kind promotes dental pulp and the regenerated composition of dentine
KR101772449B1 (en) * 2016-12-27 2017-08-30 주식회사 하이센스바이오 Novel peptide
CN107115561B (en) * 2017-06-19 2019-11-26 中山大学附属口腔医院 A kind of 3D printing timbering material and its preparation method and application
CN109846885A (en) * 2019-04-04 2019-06-07 南通大学附属医院 The new application of Rosuvastatin
RU2700933C1 (en) * 2019-05-27 2019-09-24 Артем Иванович Трофименко Hydrogel for regeneration of tooth pulp and periodontium
CN110897897B (en) * 2019-12-11 2021-03-16 四川大学 VEGF-loaded chitosan temperature control gel and preparation method and application thereof
CN113318275B (en) * 2021-08-03 2021-11-02 首都医科大学附属北京口腔医院 Degradable hydrogels for pulp dentin regeneration
CN114107184A (en) * 2021-11-26 2022-03-01 山东中医药大学第二附属医院 Application of siRNA in osteogenic differentiation of dental pulp stem cells
CN114306717B (en) * 2021-11-30 2022-07-26 中国科学院南海海洋研究所 Marine biomedical material for repairing skin wounds and preparation method and application thereof
CN114558171B (en) * 2022-04-01 2022-10-14 四川大学 Preparation method of mineral matrix gel for tooth/bone hard tissue repair and regeneration
CN115137878B (en) * 2022-06-24 2023-12-19 成都世联康健生物科技有限公司 Application of BMP7 cytokine in preparation of injection for promoting endogenous dental pulp regeneration
CN115161272A (en) * 2022-08-23 2022-10-11 首都医科大学 Method for promoting odontogenic differentiation of mesenchymal stem cells by using Wnt10a and application thereof
CN115074324B (en) * 2022-08-23 2022-11-18 首都医科大学 Wnt3a-Wnt10a biological tooth root complex and preparation method thereof
CN117379598B (en) * 2023-07-27 2024-03-22 天津医科大学口腔医院 Polymer hydrogel and preparation method and application thereof
CN117797317A (en) * 2024-02-29 2024-04-02 四川大学 Preparation method of peptide microsphere-chitosan composite material, and product and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010148229A1 (en) * 2009-06-17 2010-12-23 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
WO2012011610A1 (en) * 2010-07-21 2012-01-26 Kyoto University Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009055609A1 (en) * 2007-10-25 2009-04-30 The Trustees Of Columbia University In The City Of New York Biopulp
US8809272B2 (en) * 2010-09-09 2014-08-19 The Board Of Trustees Of The Leland Stanford Junior University Use of liposomal Wnt composition to enhance osseointegration
EP2622063A4 (en) * 2010-10-01 2014-03-26 Univ Columbia Production of dentin, cementum and enamel by cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010148229A1 (en) * 2009-06-17 2010-12-23 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
WO2012011610A1 (en) * 2010-07-21 2012-01-26 Kyoto University Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014153548A1 *

Also Published As

Publication number Publication date
WO2014153548A1 (en) 2014-09-25
EP2976044A1 (en) 2016-01-27
CN105228557A (en) 2016-01-06

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: SUN, GUOMING

Inventor name: ZHENG, YING

Inventor name: WANG, SONGLIN

Inventor name: MAO, JEREMY J.

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20161024

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/24 20060101ALI20161018BHEP

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