US20010012607A1 - Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants - Google Patents
Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants Download PDFInfo
- Publication number
- US20010012607A1 US20010012607A1 US09/832,491 US83249101A US2001012607A1 US 20010012607 A1 US20010012607 A1 US 20010012607A1 US 83249101 A US83249101 A US 83249101A US 2001012607 A1 US2001012607 A1 US 2001012607A1
- Authority
- US
- United States
- Prior art keywords
- guided
- support
- tissue regeneration
- plate
- regeneration plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0003—Not used, see subgroups
- A61C8/0004—Consolidating natural teeth
- A61C8/0006—Periodontal tissue or bone regeneration
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material
- Y10S623/919—Bone
Definitions
- This invention relates to the art of dentistry and, more particularly, to a devices which relate to the surgical placement of endosseous dental implants in the maxillary or mandibular jaw bone. Still more specifically, this invention relates to the growing of jaw bone in order to obtain adequate volume of osseous structure by using a thin titanium bone plate/screen which is mated to an underlying support bone screw or to a dental implant.
- endosseous dental implants have been well documented for over 30 years; however, the success of these endosseous dental implants has been limited by the quality and quantity of existing bone a given patient would present with. Due to the destructive nature of dentures to the underlying jaw bone as well as to the fact that bone that is not internally stimulated by tooth roots will atrophy, the amount of bone in many people is very limited for the placement of dental implants, especially for those who have been missing teeth for an extended period of time.
- Bone grafting has become an essential element for the successful treatment of those who do not have enough bone for dental implants.
- blocks of hip bone have been affixed to the jaw, and freeze-dried demineralized bone protein has been used as a stimulant to cause the patient's bone cells to become active and lay down new bone onto the existing bone areas and into the new bone graft areas.
- demineralized bone protein has been used as a stimulant to cause the patient's bone cells to become active and lay down new bone onto the existing bone areas and into the new bone graft areas.
- it has become evident that, for bone grafting to be successful, it must be given an isolated space to grow, protected from muscular pressure, tissue impingement and chewing forces.
- many approaches have been proposed. For example, both Syers (U.S. Pat. No. 5,297,563) and Magnusson et al (U.S. Pat.
- No. 4,961,707 teach the use of a fabric-like membrane which is used over a bony defect. Although this barrier creates an isolated space from the invasion of epithelial cells into the bony defect or bone graft area, it does not create a protected space from chewing forces or tissue pressure.
- the guided-tissue regeneration plate support and fixation system contemplated in accordance with the subject invention obtains the ability to place a single screw in the center of the bone graft area, thereby facilitating the selection of a screw height that allows for an exact amount of tenting, thus giving the support where it is needed most. Placement and removal of this device is greatly simplified due to the fact that peripheral screws are not required (although such can be used). The head of the screw ends up being mostly under the plate, thus preventing any concern about screw-head irritation or protrusion. Furthermore, concern about damage to neighboring peripheral structures is eliminated. In general, a much more simplified and cost effective method, apparatus and result are achieved.
- the fine mesh screen can be fabricated from any suitable material, resorptive or non-resorptive, and an especially suitable material, especially when a titanium guided-tissue support plate is employed, is fine mesh screen titanium fixed to the support plate by welding, particularly spot or laser welding, by an adhesive or by sintering the two-piece assembly.
- a functional equivalent to a fine mesh screen region can be obtained by substantially reducing the thickness of predetermined central areas of an imperforate titanium (for example) plate and then perforating the reduced thickness regions with finely spaced apertures.
- a pliable guided-tissue regeneration plate which holds it shape after being bent, is employed as a mating component to a support screw or a dental implant and is secured to the jaw structure by fixation of the guided-tissue regeneration plate at a predetermined distance above or away from the surface of the bone to the support screw or dental implant in order to create a supported and protected space between the underside of the gum tissue and the original bone which is free from muscular and chewing pressure in order to promote bone growth.
- the guided-tissue regeneration plate support and fixation system can be mated with a support screw or screws which are tenting screws designed to be mated with and then become intimately a part of the guided-tissue regeneration plate in order to grow bone in the space created by the guided-tissue regeneration plate system prior to implant placement. Additionally, the guided-tissue regeneration plate system can be utilized during implant placement by creating space adjacent to a dehisced implant by fixation of the guided-tissue regeneration plate directly to the implant in order to grow bone height or width.
- a guided-tissue regeneration plate according to the present invention can also be used by affixing it to an existing dental implant that has been previously placed and has undergone bone loss in order to regenerate new bone.
- the guided-tissue regeneration plate support and fixation system is adapted to be surgically removed after the bone has grown under its surface at a later uncovering or implant placement surgery.
- the guided-tissue regeneration plate consists of first and second integrated components including a first support plate component having a peripheral region and a generally open central portion and a fine mesh screen juxtaposed over the central portion and fixed to the peripheral region thereof.
- the guided-tissue regeneration plate is fabricated starting with an imperforate plate (for example, of titanium) and then reducing the thickness of predetermined central regions of the plate, a step which can be carried out, for example, by employing a conventional photoresist mask over the plate in conjunction with an acid etch. After the desired thickness of the central regions has been obtained, the central regions may be perforated with finely spaced apertures using, for example, conventional laser machining techniques.
- FIG. 1 illustrates a bony ridge that has undergone substantial loss
- FIG. 2 depicts a cross-section of a maxillary midline area of an edentulous ridge showing the original size prior to bone loss;
- FIG. 3 shows the surrounding tissue first reflected away from the bony ridge to expose the ridge in its entirety
- FIG. 4 depicts the mating of a guided-tissue regeneration plate component of the invention to a support screw component of a snap-fit embodiment
- FIG. 5 shows bone graft material packed beneath the plate and against the existing bony ridge
- FIG. 6 shows how the bony ridge appears after the guided-tissue regeneration plate support and fixation system has been removed to expose the new bony ridge
- FIG. 7 depicts the placement of a large implant into the new bony ridge
- FIG. 8 shows the placement of an implant into an atrophic bony ridge
- FIG. 9 depicts the installation of a guided-tissue regeneration plate using a screw supplied by an implant manufacturer
- FIG. 10 illustrates the final result of the process shown progressively in FIGS. 8, 9 and 10 ;
- FIG. 11 illustrates the manner in which the guided-tissue regeneration plate can be snap-attached over a modified healing screw made to internally thread into a dental implant
- FIG. 12 depicts a non-perforated embodiment of the guided-tissue regeneration plate
- FIG. 13 illustrates a snap configured support screw ready to receive a guided-tissue regeneration plate
- FIG. 14 depicts the guided-tissue regeneration plate over the snap configured support screw after the edges have been bent down to create a space below the guided-tissue regeneration plate;
- FIG. 15 illustrates a perforated version of the guided-tissue regeneration plate
- FIG. 16 depicts a guided-tissue regeneration plate being secured to a guided-tissue regeneration plate support screw by a small set screw
- FIG. 17 illustrates the manner in which an exemplary healing screw of the sort typically supplied by a dental implant manufacturer can be employed to secure the guided-tissue regeneration plate to a dental implant;
- FIG. 18 shows in plan view a guided tissue regeneration support plate used in an alternative preferred embodiment of the invention.
- FIG. 19 is a view similar to FIG. 18 illustrating the optional use of stabilizing members added to the central, substantially open region of the support plate;
- FIG. 20 illustrates a fine mesh screen component used in the alternative preferred embodiment of the invention
- FIG. 21 show a completed guided tissue regeneration plate according to the alternative preferred embodiment of the invention fabricated by integrating the screen shown in FIG. 20 to the support plate shown in FIGS. 18 and 19;
- FIG. 22 is a view similar to FIG. 21 illustrating a reinforced central aperture
- FIG. 23 is an enlarged cross sectional view taken along the lines 23 - 23 of FIG. 22;
- FIG. 24 is a plan view of an imperforate plate used in a variant process for preparing the alternative preferred embodiment of the invention.
- FIG. 25 is a plan view of a mask, overlaying the imperforate plate, used to define predetermined central areas of the imperforate plate to be reduced in thickness;
- FIG. 26 is a plan view of the imperforate plate after the predetermined central areas have been reduced in thickness.
- FIG. 27 is a plan view of a completed guided-tissue regeneration plate prepared by the variant process after a perforating step has been carried out.
- the described invention relates to a method of growing jaw bone and to the related guided-tissue regeneration plate support and fixation system by which an isolated and protected space free from tissue impingement, occlusal loading, chewing forces, or muscular pressure is created between the periosteum and the jaw bone.
- This space is created by first placing either a dental implant or a guided-tissue regeneration plate support and fixation system tenting-type support screw into the jaw bone and then coupling the guided-tissue regeneration plate to the support screw.
- the presently preferred embodiment of the support screws are thin shafted screws with a relatively high ratio between the greater diameter to the minor diameter of the threads to give the maximum bite and hold into the bone. Preferably, this ratio is at least two.
- the head of the tenting-type support screw is placed above or away from the bone a suitable distance of the space created in order to grow bone.
- the screw head is configured to receive the guided-tissue regeneration plate, thus allowing for most of the head to be either in or under the guided-tissue regeneration plate after it is engaged into a receiver cap of the head.
- the head of the support screw is internally axially threaded or is provided with a threaded or non-threaded well allowing for a pin with a small head resembling a micro thumbtack to extend through the guided-tissue regeneration plate into the well and snap or thread into place, thereby securing the guided-tissue regeneration plate to the head of the tenting-type support screw.
- the support screw is preferably fabricated to be very sharp at its tip which includes a self-starting flute in order to facilitate self-threading for facilitating placement.
- the guided-tissue regeneration plate is preferably made of thin titanium sheet metal having a peripheral thickness of around 5 to 10 thousandths of an inch. This thickness allows for the material to be thin enough to be bent into shape, but rigid enough to hold its shape after being bent and molded.
- the present material of choice is Grade 1 titanium which is the fully annealed form of titanium advantageously characterized in that it will not spring back after being bent.
- the plates are fabricated with a precise aperture proximate the center or wherever needed in order to allow for a precise union and mating to the support screw or receiver cap of the healing screw of a dental implant, thus giving a secure fixation, by indirect means, to the jaw bone.
- the central area of the guided-tissue regeneration plate is preferably thicker in order to provide more support and rigidity than the peripheral region. The combination of the support screw and the thicker area of the plate near the center prevents the guided-tissue regeneration plate from caving-in in the area where maximum support is needed when overlying pressure, such as muscular pressure, chewing forces, or any other premature loading onto the guided-tissue regeneration plate support and fixation system, is later applied.
- the guided-tissue regeneration plate can optionally be perforated to allow for better overlying tissue healing as well as to promote the exchange of nutrients and blood supply between the bone graft and the overlying tissue.
- the central, thicker, more supportive area is not perforated to obtain more support.
- the number and size of the perforations is less concentrated than the amount of solid space to create a more supportive plate at a thinner dimension. If a completely imperforate barrier is desired to isolate all transfer of unwanted epithelial cells into the bone graft area, then the guided-tissue regeneration plate is fabricated imperforate except for the generally centrally disposed aperture for fixing the plate to its support screw.
- a resorptive barrier such as VicrylTM, collagen, resorptive hydroxyapatite crystals or GuidorTM can be applied to the under or over side of the guided-tissue regeneration plate to seal the perforations, then resorbing a limited time later after the system is installed.
- the perforations can be covered by applying a suitable material such as PTFE fibers. After a period of several months have passed, the entire system is removed and then the implants are either simultaneously placed during this surgery or uncovered by placing healing caps into the implants. If the only desired effect is to create a better ridge for the stabilization of a denture, then the system may be left in place indefinitely.
- a suitable material such as PTFE fibers.
- FIG. 1 shows an exemplary existing midline cross-section of a maxillary edentulous ridge which has undergone substantial bone loss.
- landmarks can be identified by the palatal bone 1 , the floor of the nose 2 , the bony ridge 3 , and the gum tissue 4 .
- FIG. 2 depicts a cross-section of a maxillary midline area of an edentulous ridge showing the original size prior to bone loss (the gum tissue is not shown in this view). Reference is taken to the marrow space 5 , the cortical bone 6 and the current size of the ridge 7 after bone loss and to the area of the original size 8 of the ridge prior to atrophy or bone loss.
- the tissue is first reflected away from the bony ridge to expose the ridge in its entirety.
- the palatal gum tissue 9 is reflected 9
- the facial gum tissue 10 is reflected
- a guided-tissue regeneration plate support screw 11 is placed into the bony ridge.
- FIG. 4 depicts the mating of the guided-tissue regeneration plate 12 to a guided-tissue regeneration support screw 11 of the snap-fit embodiment.
- the gum tissue is not shown.
- the space 13 is the area where new bone will grow, the space having been created by the guided-tissue regeneration plate support and fixation system of the invention.
- the guided-tissue regeneration plate support screw 11 is placed into the bony ridge 3 .
- the guided-tissue regeneration plate 12 is affixed to the guided-tissue regeneration plate support screw 11 by snapping it in place, the plate is molded into shape by bending the edges down as shown.
- FIG. 6 shows how the bony ridge appears after the guided-tissue regeneration plate support and fixation system has been removed to expose the new bony ridge 15 .
- a small hole 16 remains after the removal of the guided-tissue regeneration plate support screw. (Gum tissue not shown.)
- FIG. 7 depicts the placement of a large implant 17 into the new bony ridge. A tooth can be attached to the implant later.
- FIG. 8 shows the placement of an implant 17 into an atrophic bony ridge 3 .
- the implant is not fully encased in bone resulting in an exposed area 18 of the implant outside the confines of the existing bone 3 .
- FIG. 9 depicts the installation of a guided-tissue regeneration plate 12 by inserting the healing screw 19 supplied by the implant manufacturer which can be used in place of a tenting-type support screw to mate the guided-tissue regeneration plate 12 directly to the implant 17 .
- This screw 19 extends through the aperture of the guided-tissue regeneration plate 12 and is thus used instead of the snap-type embodiment previously described.
- the space 13 created by the guided-tissue regeneration plate 12 is filled with bone graft material, thus covering the exposed portion of the dental implant 18 which is out of the confines of the existing resorbed bony ridge 3 .
- FIG. 10 illustrates the final result of the process shown progressively in FIGS. 8, 9, 10 after the removal of the guided-tissue regeneration plate (not shown) by revealing that the dental implant 17 is now covered with new bone 20 that has grown around the dental implant after four-to-eight months of healing time and the subsequent removal of the guided-tissue regeneration plate system.
- a post has been placed into the dental implant 17 as normal followed by a crown or tooth 22 which is secured to the post in the well known manner.
- FIG. 11 illustrates the manner in which the guided-tissue regeneration plate 12 can be snap-attached over a modified healing screw 23 made to internally thread into a dental implant 17 .
- the modified healing screw 23 has a receiver cap 24 adapted to receive the generally centrally disposed aperture in the guided-tissue regeneration plate 12 .
- FIG. 12 depicts a non-perforated embodiment 30 of the guided-tissue regeneration plate, particularly illustrating the generally central aperture 31 by which the guided-tissue regeneration plate may be secured using a screw as previously described.
- FIG. 13 depicts the snap configured support screw 11 ready to receive the guided-tissue regeneration plate 30 through the aperture 31 . Attention is also directed to the cross-section of the guided-tissue regeneration plate 30 which includes a relatively thick central region 32 and a thinner peripheral region 33 as previously described.
- FIG. 14 depicts the mating of the guided-tissue regeneration plate 30 over the snap configured support screw 11 after the edges have been bent down to create the space below the guided-tissue regeneration plate.
- FIG. 15 illustrates a perforated version 35 of the guided-tissue regeneration plate which allows for blood supply to pass freely through the plate. Note the generally centrally disposed aperture 25 .
- FIG. 16 depicts a guided-tissue regeneration plate 35 being secured to a guided-tissue regeneration plate support screw 26 by a small set screw 27 which is placed through the aperture 25 in the guided-tissue regeneration plate and into the support screw 26 which has an internally threaded, axially oriented blind hole 36 in its top.
- FIG. 17 illustrates the manner in which an exemplary healing screw 19 of the sort typically supplied by a dental implant manufacturer can be employed to secure the guided-tissue regeneration plate 12 to the dental implant 17 .
- FIG. 18 there is shown a guided-tissue regeneration support plate 40 which is a first component of the alternative preferred embodiment for the guided-tissue regeneration plate.
- the support plate 40 has generally open regions 41 , 44 defined, in the exemplary configuration, by integral struts 42 radiating from a central inner support ring 43 to the main body of the support plate.
- the central inner support ring 43 and defined space 44 may be dimensioned and configured to serve the same fixation purpose as the apertures 31 and 35 in the respective guided-tissue regeneration plates 30 , 35 as described above.
- the main body of the support plate 40 i.e., that portion which is generally outboard the struts 42 , the inner support ring 43 and the open regions 41 , 44 , is somewhat thicker than the guided-tissue regeneration plates 30 , 35 previously described.
- the thickness of the support plate 40 may be on the order of 0.008-0.025 of an inch and preferably about 0.020 of an inch.
- the material, as noted with respect to the guided-tissue regeneration plates 30 , 35 should be bio-compatible, and other metals which are suitable include chromium cobalt alloy and Teflon-coated surgical steel.
- any suitable configuration of the support plate 40 may be employed to provide a peripheral region of sufficient strength and rigidity as to be readily manually shaped to the contours necessary to be fitted to the region above the bony ridge of a given patient as previously described above while providing substantial open regions 41 , 44 surrounded by the peripheral region.
- the configuration shown in FIG. 18 has proven to be a good combination of strength and intended purpose.
- numerous perforations 45 are provided in the support plate. Because of the increased thickness of the support plate 40 in comparison to that of the guided-tissue regeneration plate 35 , the perforations 45 are preferably mutually closely spaced consistent with not compromising the strength of the support plate.
- the widths of the supplementary struts 48 may fall within the same range as those of the struts 42 while the widths or diameters (if titanium wire is used), i.e., the largest transverse dimension, of the minor struts 46 , 47 may be smaller yet, falling within the range 0.010-0.020 of an inch, preferably about 0.015 of an inch.
- the method of fixation of the supplementary strut(s) 47 , 47 , 48 may be by any suitable expedient such as welding, spot welding, laser welding, adhesive or sintering.
- FIG. 20 shows a second component of the alternative preferred embodiment for the guided-tissue regeneration plate.
- This second component is a fine mesh screen 50 .
- the diameter of the wire may be in the range of about 0.002-0.006 of an inch, and preferably about 0.003 of an inch disposed in a fine mesh weave on the order of 10 ⁇ 10 wires per inch to 200 ⁇ 200 wires per inch and preferably about 50 ⁇ 50 per inch.
- the fine mesh screen 50 is juxtaposed onto the support plate 40 generally centrally disposed over the open areas 41 and fixed in place by any means suitable to the material(s) employed.
- sintering i.e., heating the complete assembly until the titanium components have fused at the points of abutment
- the supplementary struts 48 and/or minor struts 46 , 47 may be integrated into the structure during the same sintering step.
- the size parameters discussed above for titanium are also suitable, and the fixation of the fine mesh screen 50 to the support plate 40 may be carried out in the same manner when chromium cobalt alloy is employed.
- Teflon-coated surgical steel a compatible fixation method must be employed.
- the Teflon coating may be first scraped away in the regions of abutment between the two components before the joining step is carried out, or a special purpose adhesive may be used.
- the Teflon coating is more practically applied after the two-piece structure has been fabricated.
- the resulting two-piece (plus supplementary and/or minor struts) guided-tissue regeneration plate 49 shown in FIG. 21 can then be used in the process described above with notably improved results with respect to the speed and quality with which jaw bone is regenerated along a patient's bony ridge and thicker and more healthy overlying periosteum. Consequently, the long term outlook for the integrity of subsequent dental implants is correspondingly improved, a more satisfactory result having been obtained more quickly.
- FIGS. 22 and 23 illustrate a reinforced central inner support ring 43 . More particularly, as best shown in the enlarged fragmentary cross section of FIG. 23, the thickness of the central inner support ring 43 may be augmented by any suitable means such as by stacking additional material 43 A over the support ring 43 which is integral with the struts 42 as previously described.
- FIG. 24 shows an imperforate monolithic plate 60 having peripheral outer dimensions corresponding to those of the guided-tissue regeneration plate 49 shown in FIG. 22.
- a preferred material is titanium plate having a thickness of about 0.008-0.025 of an inch and preferably about 0.012 of an inch.
- the imperforate plate 60 is subjected to further processing to obtain the desired guided-tissue regeneration plate as a unitary structure.
- a suitable configured mask 61 is prepared and juxtaposed overlaying one surface of the plate.
- the mask 61 may be a separate stencil-like layer or may be deposited directly on the surface of the plate 60 by a conventional technique such as by depositing a photo-resist layer applied in the desired pattern; i.e., a pattern which will shield the areas of the plate 60 which are not to be reduced in thickness. Accordingly, the areas which are not coated or otherwise masked off are subject to reduction in thickness.
- radial struts 64 of the mask 61 define a series of circumferentially distributed openings 62 while arms adjoining adjacent radial struts 64 define supplementary struts 65 which corresponds to the supplementary struts 48 shown in FIGS. 19, 21 and 22 and discussed above.
- the rectangular configuration of the supplementary struts 65 and the inner ends of the radial struts 64 define additional openings 67 .
- the inner ends of the radial struts 64 each terminate at a ring 66 which circumscribes central mask opening 63 .
- the masked surface can be subjected to a conventional acid etch to remove unprotected metal and hence reduce the thickness of the plate 60 in the unmasked areas to the previously discussed range of 0.002-0.006 of an inch and preferably about 0.003 of an inch.
- the rate and extent of the metal removal can be controlled, as well known in the art, by selecting the type of acid, its concentration and temperature and the length of time the plate is subjected to the acid.
- FIG. 26 shows the plate 60 A after the acid etch step has been completed.
- regions 68 , 69 , 70 will be understood to be of diminished thickness while the strut regions 71 , supplementary strut regions 72 , central ring region 73 and peripheral region 74 remain at the original thickness of the plate because they were protected by the mask during the etching operation.
- the second variant of the second preferred embodiment of the guided-tissue regeneration plate is competed by perforating its surface with a large number of closely spaced apertures, typically circular in shape.
- the guided-tissue regeneration plate 60 B has been pierced by numerous closely spaced apertures 75 in the regions 71 , 72 , 73 , 74 of the plate which were not reduced in thickness.
- the plate is pierced even more densely with numerous closely spaced apertures 76 .
- the central aperture 70 is opened through the plate 60 B during the finishing process to serve as a fixation screw receiving opening in the same manner as previously described with respect to the central aperture 44 (FIGS. 22, 23) of the two-piece first variant of the alternative preferred embodiment for the guided-tissue regeneration plate.
- the size and spacing of the apertures in both the original thickness and the reduced thickness regions of the guided-tissue regeneration plate 60 B affects both the porosity and the mechanical pliability of the individual regions.
- the spacing can be either random as shown for the majority of the areas in FIG. 27 or in a definite pattern as shown in the regions 76 (a thinned-down region) and 77 (an original thickness region—not enlarged).
- the regions 76 and 77 are contrasted by the use of smaller apertures and finer spacing in the reduced thickness region 76 , thus achieving increased porosity.
- the larger apertures and wider spacing employed in the original thickness region 77 provides a stiffer, but still compliant, structure for the peripheral region 74 which achieves a structure mechanically well-adapted for emplacement and subsequent maintenance of its position and configuration in use.
- one or more minor struts may be provided as necessary to ensure sufficient rigidity to the screened portion of the first variant of the alternative preferred embodiment for the guided-tissue regeneration plate.
- Corresponding minor struts may also be incorporated into the second variant of the alternative preferred embodiment for the guided-tissue regeneration plate shown in FIG. 27 by either making provision for such in the mask 61 or by later affixing them, as separate components in the manner previously described, to the unitary structure.
- the presently preferred material for either version of the alternative preferred embodiment is titanium, the use of other materials, non-resorptive and resorptive, as discussed above may be employed.
- the variant preferred embodiment of the guided-tissue regeneration plate may be left in place or removed prior to the implantation process as may be appropriate for a given patient.
- a resorptive barrier such as VicrylTM, collagen, resorptive hydroxyapatite crystals or GuidorTM can be applied to the top or bottom side of the guided-tissue regeneration plates 49 , 60 B to seal the perforations, then resorbing a limited time later after the system is installed.
Abstract
A method of growing jaw bone and the related guided-tissue regeneration plate support and fixation system employed in the method where an isolated and protected space free from tissue impingement, occlusal loading, chewing forces or muscular pressure is created between the periosteum and the jaw bone. This space is created by first placing either a dental implant or a guided-tissue regeneration plate support and fixation system tenting-type support screw into the jaw bone. The plate portion of the guided-tissue regeneration plate support and fixation system, preferably made out of titanium, is a two-piece structure including a first support plate component having a peripheral region and a generally open central portion and a fine mesh screen juxtaposed over the central portion of the support plate and fixed to the peripheral region thereof. Alternatively, a titanium blank can be controllably etched to obtain reduced thickness central regions which, along with the original thickness regions, are methodically pierced to obtain numerous apertures to achieve the desired porosity for the central regions and the desired strength and pliability of the peripheral regions. The guided-tissue regeneration plate is either snapped-down onto the head of the support screw or onto a specialized and modified healing screw of a dental implant which has a receiver cap or is screwed directly into a dental implant. The plate is then bent and molded into the proper shape to provide the protected space.
Description
- This is a Continuation-in-Part of U.S. patent application Ser. No. 08/609,870, filed Mar. 1, 1996, by Dane Q. Robinson and entitled METHOD AND APPARATUS FOR GROWING JAW BONE UTILIZING A GUIDED-TISSUE REGENERATION PLATE SUPPORT AND FIXATION SYSTEM, now U.S. Pat. No. 5,839,899.
- This invention relates to the art of dentistry and, more particularly, to a devices which relate to the surgical placement of endosseous dental implants in the maxillary or mandibular jaw bone. Still more specifically, this invention relates to the growing of jaw bone in order to obtain adequate volume of osseous structure by using a thin titanium bone plate/screen which is mated to an underlying support bone screw or to a dental implant.
- The successful placement of endosseous dental implants has been well documented for over 30 years; however, the success of these endosseous dental implants has been limited by the quality and quantity of existing bone a given patient would present with. Due to the destructive nature of dentures to the underlying jaw bone as well as to the fact that bone that is not internally stimulated by tooth roots will atrophy, the amount of bone in many people is very limited for the placement of dental implants, especially for those who have been missing teeth for an extended period of time.
- Bone grafting has become an essential element for the successful treatment of those who do not have enough bone for dental implants. As viable methods, blocks of hip bone have been affixed to the jaw, and freeze-dried demineralized bone protein has been used as a stimulant to cause the patient's bone cells to become active and lay down new bone onto the existing bone areas and into the new bone graft areas. Through experience and research, it has become evident that, for bone grafting to be successful, it must be given an isolated space to grow, protected from muscular pressure, tissue impingement and chewing forces. In order to create this space, many approaches have been proposed. For example, both Syers (U.S. Pat. No. 5,297,563) and Magnusson et al (U.S. Pat. No. 4,961,707) teach the use of a fabric-like membrane which is used over a bony defect. Although this barrier creates an isolated space from the invasion of epithelial cells into the bony defect or bone graft area, it does not create a protected space from chewing forces or tissue pressure.
- Morgan (U.S. Pat. No. 5,380,328) teaches the use of a composite perforated titanium mesh layered with polytetrafluoraethylene (PTFE or Teflon®) fibers. Even though this approach would be feasible for creating a protected space in order to grow bone, it has some severe limitations. This material requires the placement of peripheral bone screws into the edges of the meshed piece in order to create a direct fixation of the titanium mesh to the jaw bone and then bowing-up or tenting-up the center area in order to create the protected space. Often, it would not be feasible to place the peripheral bone screws in the peripheral areas for fear of damage to the inferior alveolar nerves or sinus penetration or damage to nearby tooth roots. The protrusion of these screws above the mesh is also of concern as potentially causing a tissue irritation complication with this given procedure.
- Furthermore, the difficulty of forming the exact amount of tenting desired with this material is inherently very difficult to control. Additionally, the removal of this material is complicated by the need to surgically dissect much deeper to locate the peripheral screws. This technique would also be expensive and time consuming to emplace due to the need for multiple screws to secure a single mesh.
- On the other hand, as will become more apparent below, the guided-tissue regeneration plate support and fixation system contemplated in accordance with the subject invention obtains the ability to place a single screw in the center of the bone graft area, thereby facilitating the selection of a screw height that allows for an exact amount of tenting, thus giving the support where it is needed most. Placement and removal of this device is greatly simplified due to the fact that peripheral screws are not required (although such can be used). The head of the screw ends up being mostly under the plate, thus preventing any concern about screw-head irritation or protrusion. Furthermore, concern about damage to neighboring peripheral structures is eliminated. In general, a much more simplified and cost effective method, apparatus and result are achieved.
- Experience with and further development of the guided-tissue regeneration plate support and fixation system has resulted in an important advance which enhances its effectiveness in practice. It has been found that the use of a fine mesh screen spanning open areas of a guided-tissue regeneration support plate results in a faster and more complete bone regeneration of the underlying bony ridge and faster and more healthy growth of the overlying periosteum. The fine mesh screen can be fabricated from any suitable material, resorptive or non-resorptive, and an especially suitable material, especially when a titanium guided-tissue support plate is employed, is fine mesh screen titanium fixed to the support plate by welding, particularly spot or laser welding, by an adhesive or by sintering the two-piece assembly. Alternatively, a functional equivalent to a fine mesh screen region can be obtained by substantially reducing the thickness of predetermined central areas of an imperforate titanium (for example) plate and then perforating the reduced thickness regions with finely spaced apertures.
- It is therefore a broad object of my invention to provide an improved dental implant system.
- It is a more specific object of my invention o provide an improved dental implant system which is relatively inexpensive to fabricate and use.
- In another aspect, it is an object of my invention to provide a dental implant system which is relatively easy to use to obtain high quality results.
- Briefly, these and other objects of the invention are achieved by a method of growing additional maxillary or mandibular bone in areas of atrophy and by the use of a related device to accomplish the task. A pliable guided-tissue regeneration plate, which holds it shape after being bent, is employed as a mating component to a support screw or a dental implant and is secured to the jaw structure by fixation of the guided-tissue regeneration plate at a predetermined distance above or away from the surface of the bone to the support screw or dental implant in order to create a supported and protected space between the underside of the gum tissue and the original bone which is free from muscular and chewing pressure in order to promote bone growth.
- The guided-tissue regeneration plate support and fixation system can be mated with a support screw or screws which are tenting screws designed to be mated with and then become intimately a part of the guided-tissue regeneration plate in order to grow bone in the space created by the guided-tissue regeneration plate system prior to implant placement. Additionally, the guided-tissue regeneration plate system can be utilized during implant placement by creating space adjacent to a dehisced implant by fixation of the guided-tissue regeneration plate directly to the implant in order to grow bone height or width. A guided-tissue regeneration plate according to the present invention can also be used by affixing it to an existing dental implant that has been previously placed and has undergone bone loss in order to regenerate new bone. The guided-tissue regeneration plate support and fixation system is adapted to be surgically removed after the bone has grown under its surface at a later uncovering or implant placement surgery. In an alternative preferred embodiment which provides particularly successful results and which results in faster and better bone regeneration and periosteum growth, the guided-tissue regeneration plate consists of first and second integrated components including a first support plate component having a peripheral region and a generally open central portion and a fine mesh screen juxtaposed over the central portion and fixed to the peripheral region thereof. In a functionally equivalent variant of the alternative preferred embodiment, the guided-tissue regeneration plate is fabricated starting with an imperforate plate (for example, of titanium) and then reducing the thickness of predetermined central regions of the plate, a step which can be carried out, for example, by employing a conventional photoresist mask over the plate in conjunction with an acid etch. After the desired thickness of the central regions has been obtained, the central regions may be perforated with finely spaced apertures using, for example, conventional laser machining techniques.
- The subject matter of the invention is particularly pointed out and distinctly claimed in the concluding portion of the specification. The invention, however, both as to organization and method of operation, may best be understood by reference to the following description taken in conjunction with the subjoined claims and the accompanying drawing of which:
- FIG. 1 illustrates a bony ridge that has undergone substantial loss;
- FIG. 2 depicts a cross-section of a maxillary midline area of an edentulous ridge showing the original size prior to bone loss;
- FIG. 3 shows the surrounding tissue first reflected away from the bony ridge to expose the ridge in its entirety;
- FIG. 4 depicts the mating of a guided-tissue regeneration plate component of the invention to a support screw component of a snap-fit embodiment;
- FIG. 5 shows bone graft material packed beneath the plate and against the existing bony ridge;
- FIG. 6 shows how the bony ridge appears after the guided-tissue regeneration plate support and fixation system has been removed to expose the new bony ridge;
- FIG. 7 depicts the placement of a large implant into the new bony ridge;
- FIG. 8 shows the placement of an implant into an atrophic bony ridge;
- FIG. 9 depicts the installation of a guided-tissue regeneration plate using a screw supplied by an implant manufacturer;
- FIG. 10 illustrates the final result of the process shown progressively in FIGS. 8, 9 and10;
- FIG. 11 illustrates the manner in which the guided-tissue regeneration plate can be snap-attached over a modified healing screw made to internally thread into a dental implant;
- FIG. 12 depicts a non-perforated embodiment of the guided-tissue regeneration plate;
- FIG. 13 illustrates a snap configured support screw ready to receive a guided-tissue regeneration plate;
- FIG. 14 depicts the guided-tissue regeneration plate over the snap configured support screw after the edges have been bent down to create a space below the guided-tissue regeneration plate;
- FIG. 15 illustrates a perforated version of the guided-tissue regeneration plate;
- FIG. 16 depicts a guided-tissue regeneration plate being secured to a guided-tissue regeneration plate support screw by a small set screw; and
- FIG. 17 illustrates the manner in which an exemplary healing screw of the sort typically supplied by a dental implant manufacturer can be employed to secure the guided-tissue regeneration plate to a dental implant;
- FIG. 18 shows in plan view a guided tissue regeneration support plate used in an alternative preferred embodiment of the invention;
- FIG. 19 is a view similar to FIG. 18 illustrating the optional use of stabilizing members added to the central, substantially open region of the support plate;
- FIG. 20 illustrates a fine mesh screen component used in the alternative preferred embodiment of the invention;
- FIG. 21. show a completed guided tissue regeneration plate according to the alternative preferred embodiment of the invention fabricated by integrating the screen shown in FIG. 20 to the support plate shown in FIGS. 18 and 19;
- FIG. 22 is a view similar to FIG. 21 illustrating a reinforced central aperture;
- FIG. 23 is an enlarged cross sectional view taken along the lines23-23 of FIG. 22;
- FIG. 24 is a plan view of an imperforate plate used in a variant process for preparing the alternative preferred embodiment of the invention;
- FIG. 25 is a plan view of a mask, overlaying the imperforate plate, used to define predetermined central areas of the imperforate plate to be reduced in thickness;
- FIG. 26 is a plan view of the imperforate plate after the predetermined central areas have been reduced in thickness; and
- FIG. 27 is a plan view of a completed guided-tissue regeneration plate prepared by the variant process after a perforating step has been carried out.
- The described invention relates to a method of growing jaw bone and to the related guided-tissue regeneration plate support and fixation system by which an isolated and protected space free from tissue impingement, occlusal loading, chewing forces, or muscular pressure is created between the periosteum and the jaw bone. This space is created by first placing either a dental implant or a guided-tissue regeneration plate support and fixation system tenting-type support screw into the jaw bone and then coupling the guided-tissue regeneration plate to the support screw.
- The presently preferred embodiment of the support screws, preferably made out of (but not limited to) titanium, are thin shafted screws with a relatively high ratio between the greater diameter to the minor diameter of the threads to give the maximum bite and hold into the bone. Preferably, this ratio is at least two. The head of the tenting-type support screw is placed above or away from the bone a suitable distance of the space created in order to grow bone. The screw head is configured to receive the guided-tissue regeneration plate, thus allowing for most of the head to be either in or under the guided-tissue regeneration plate after it is engaged into a receiver cap of the head.
- In another contemplated embodiment of the support screws, the head of the support screw is internally axially threaded or is provided with a threaded or non-threaded well allowing for a pin with a small head resembling a micro thumbtack to extend through the guided-tissue regeneration plate into the well and snap or thread into place, thereby securing the guided-tissue regeneration plate to the head of the tenting-type support screw. The support screw is preferably fabricated to be very sharp at its tip which includes a self-starting flute in order to facilitate self-threading for facilitating placement.
- The guided-tissue regeneration plate is preferably made of thin titanium sheet metal having a peripheral thickness of around 5 to 10 thousandths of an inch. This thickness allows for the material to be thin enough to be bent into shape, but rigid enough to hold its shape after being bent and molded. The present material of choice is Grade 1 titanium which is the fully annealed form of titanium advantageously characterized in that it will not spring back after being bent.
- The plates are fabricated with a precise aperture proximate the center or wherever needed in order to allow for a precise union and mating to the support screw or receiver cap of the healing screw of a dental implant, thus giving a secure fixation, by indirect means, to the jaw bone. The central area of the guided-tissue regeneration plate is preferably thicker in order to provide more support and rigidity than the peripheral region. The combination of the support screw and the thicker area of the plate near the center prevents the guided-tissue regeneration plate from caving-in in the area where maximum support is needed when overlying pressure, such as muscular pressure, chewing forces, or any other premature loading onto the guided-tissue regeneration plate support and fixation system, is later applied.
- The guided-tissue regeneration plate can optionally be perforated to allow for better overlying tissue healing as well as to promote the exchange of nutrients and blood supply between the bone graft and the overlying tissue. Generally, the central, thicker, more supportive area is not perforated to obtain more support. Typically, the number and size of the perforations is less concentrated than the amount of solid space to create a more supportive plate at a thinner dimension. If a completely imperforate barrier is desired to isolate all transfer of unwanted epithelial cells into the bone graft area, then the guided-tissue regeneration plate is fabricated imperforate except for the generally centrally disposed aperture for fixing the plate to its support screw.
- However, if a temporary period of isolation from epithelial cells is desired to create a membrane barrier from epithelial cells for a limited period of time which allows for the exchange of nutrients, ions, and tissue fluid or perhaps blood supply, then a resorptive barrier such as Vicryl™, collagen, resorptive hydroxyapatite crystals or Guidor™ can be applied to the under or over side of the guided-tissue regeneration plate to seal the perforations, then resorbing a limited time later after the system is installed.
- If a non-resorptive semi-permeable result is desired, then the perforations can be covered by applying a suitable material such as PTFE fibers. After a period of several months have passed, the entire system is removed and then the implants are either simultaneously placed during this surgery or uncovered by placing healing caps into the implants. If the only desired effect is to create a better ridge for the stabilization of a denture, then the system may be left in place indefinitely.
- Having now discussed the fundamentals of the present invention, attention is invited to the several FIGS. for an alternative and clarifying disclosure as the discussion proceeds.
- FIG. 1 shows an exemplary existing midline cross-section of a maxillary edentulous ridge which has undergone substantial bone loss. For orientation purposes, landmarks can be identified by the palatal bone1, the floor of the
nose 2, thebony ridge 3, and the gum tissue 4. - FIG. 2 depicts a cross-section of a maxillary midline area of an edentulous ridge showing the original size prior to bone loss (the gum tissue is not shown in this view). Reference is taken to the marrow space5, the cortical bone 6 and the current size of the ridge 7 after bone loss and to the area of the original size 8 of the ridge prior to atrophy or bone loss.
- Referring now to FIG. 3, in order to place a guided-tissue regeneration plate support and fixation system according to the present invention, the tissue is first reflected away from the bony ridge to expose the ridge in its entirety. The
palatal gum tissue 9 is reflected 9, thefacial gum tissue 10 is reflected, and a guided-tissue regeneration plate support screw 11 is placed into the bony ridge. - FIG. 4 depicts the mating of the guided-
tissue regeneration plate 12 to a guided-tissue regeneration support screw 11 of the snap-fit embodiment. (The gum tissue is not shown.) Thespace 13 is the area where new bone will grow, the space having been created by the guided-tissue regeneration plate support and fixation system of the invention. The guided-tissue regeneration plate support screw 11 is placed into thebony ridge 3. After the guided-tissue regeneration plate 12 is affixed to the guided-tissue regeneration plate support screw 11 by snapping it in place, the plate is molded into shape by bending the edges down as shown. - As shown in FIG. 5, once the guided-
tissue regeneration plate 12 has been molded into place, thenbone graft material 14 is packed beneath theplate 12 and against the existingbony ridge 3. After a period of approximately four-to-eight months, a new bony ridge will form within the space created by the guided-tissue regeneration plate support and fixation system. (Gum tissue not shown.) - Thus, FIG. 6 shows how the bony ridge appears after the guided-tissue regeneration plate support and fixation system has been removed to expose the new
bony ridge 15. Asmall hole 16 remains after the removal of the guided-tissue regeneration plate support screw. (Gum tissue not shown.) - FIG. 7 depicts the placement of a
large implant 17 into the new bony ridge. A tooth can be attached to the implant later. - FIG. 8 shows the placement of an
implant 17 into an atrophicbony ridge 3. In this environment, the implant is not fully encased in bone resulting in an exposedarea 18 of the implant outside the confines of the existingbone 3. - FIG. 9 depicts the installation of a guided-
tissue regeneration plate 12 by inserting thehealing screw 19 supplied by the implant manufacturer which can be used in place of a tenting-type support screw to mate the guided-tissue regeneration plate 12 directly to theimplant 17. Thisscrew 19 extends through the aperture of the guided-tissue regeneration plate 12 and is thus used instead of the snap-type embodiment previously described. Thespace 13 created by the guided-tissue regeneration plate 12 is filled with bone graft material, thus covering the exposed portion of thedental implant 18 which is out of the confines of the existing resorbedbony ridge 3. - FIG. 10 illustrates the final result of the process shown progressively in FIGS. 8, 9,10 after the removal of the guided-tissue regeneration plate (not shown) by revealing that the
dental implant 17 is now covered withnew bone 20 that has grown around the dental implant after four-to-eight months of healing time and the subsequent removal of the guided-tissue regeneration plate system. As will be apparent to those skilled in the art, after the removal of the guided-tissue regeneration plate, a post has been placed into thedental implant 17 as normal followed by a crown or tooth 22 which is secured to the post in the well known manner. - FIG. 11 illustrates the manner in which the guided-
tissue regeneration plate 12 can be snap-attached over a modifiedhealing screw 23 made to internally thread into adental implant 17. The modifiedhealing screw 23 has areceiver cap 24 adapted to receive the generally centrally disposed aperture in the guided-tissue regeneration plate 12. - FIG. 12 depicts a
non-perforated embodiment 30 of the guided-tissue regeneration plate, particularly illustrating the generallycentral aperture 31 by which the guided-tissue regeneration plate may be secured using a screw as previously described. - FIG. 13 depicts the snap configured support screw11 ready to receive the guided-
tissue regeneration plate 30 through theaperture 31. Attention is also directed to the cross-section of the guided-tissue regeneration plate 30 which includes a relatively thickcentral region 32 and a thinnerperipheral region 33 as previously described. - FIG. 14 depicts the mating of the guided-
tissue regeneration plate 30 over the snap configured support screw 11 after the edges have been bent down to create the space below the guided-tissue regeneration plate. - FIG. 15 illustrates a
perforated version 35 of the guided-tissue regeneration plate which allows for blood supply to pass freely through the plate. Note the generally centrally disposedaperture 25. - FIG. 16 depicts a guided-
tissue regeneration plate 35 being secured to a guided-tissue regenerationplate support screw 26 by a small set screw 27 which is placed through theaperture 25 in the guided-tissue regeneration plate and into thesupport screw 26 which has an internally threaded, axially orientedblind hole 36 in its top. - FIG. 17 illustrates the manner in which an
exemplary healing screw 19 of the sort typically supplied by a dental implant manufacturer can be employed to secure the guided-tissue regeneration plate 12 to thedental implant 17. - While the guided-tissue regeneration plate system described above has worked well, experience and further development of the fundamental concept has resulted in an alternative preferred embodiment for the guided-tissue regeneration plate component which is discussed below in conjunction with FIGS.18-21. Thus, referring to FIG. 18, there is shown a guided-tissue
regeneration support plate 40 which is a first component of the alternative preferred embodiment for the guided-tissue regeneration plate. Thesupport plate 40 has generallyopen regions integral struts 42 radiating from a centralinner support ring 43 to the main body of the support plate. If desired, the centralinner support ring 43 and definedspace 44 may be dimensioned and configured to serve the same fixation purpose as theapertures tissue regeneration plates - The main body of the
support plate 40, i.e., that portion which is generally outboard thestruts 42, theinner support ring 43 and theopen regions tissue regeneration plates support plate 40 may be on the order of 0.008-0.025 of an inch and preferably about 0.020 of an inch. The material, as noted with respect to the guided-tissue regeneration plates - It will be understood that any suitable configuration of the
support plate 40 may be employed to provide a peripheral region of sufficient strength and rigidity as to be readily manually shaped to the contours necessary to be fitted to the region above the bony ridge of a given patient as previously described above while providing substantialopen regions support plate 40 and to expose the underlying bone and tissue to the passage of nutrients for the additional reasons discussed above with respect to the guided-tissue regeneration plate 35,numerous perforations 45 are provided in the support plate. Because of the increased thickness of thesupport plate 40 in comparison to that of the guided-tissue regeneration plate 35, theperforations 45 are preferably mutually closely spaced consistent with not compromising the strength of the support plate. - Referring also to FIG. 19, the
struts 42 should be as narrow as reasonably possible while remaining not subject to easy tearing. For example, widths for thestruts 42 within the range 0.020-0.030 of an inch, and preferably about 0.025 of an inch, are suitable when the presently preferred material, titanium, is used. Should the central portion still be somewhat week for the intended purpose (which will become more apparent below), one or more supplementaryrectangular struts 48 and/or one or more intermediate,minor struts struts 42 to provide increased rigidity, either on the upper or lower plane of thesupport plate 40. The widths of the supplementary struts 48 may fall within the same range as those of thestruts 42 while the widths or diameters (if titanium wire is used), i.e., the largest transverse dimension, of the minor struts 46, 47 may be smaller yet, falling within the range 0.010-0.020 of an inch, preferably about 0.015 of an inch. The method of fixation of the supplementary strut(s) 47, 47, 48 may be by any suitable expedient such as welding, spot welding, laser welding, adhesive or sintering. - Attention is now directed to FIG. 20 which shows a second component of the alternative preferred embodiment for the guided-tissue regeneration plate. This second component is a
fine mesh screen 50. When the presently preferred material, titanium, is used, the diameter of the wire may be in the range of about 0.002-0.006 of an inch, and preferably about 0.003 of an inch disposed in a fine mesh weave on the order of 10×10 wires per inch to 200×200 wires per inch and preferably about 50×50 per inch. Referring also to FIG. 21, thefine mesh screen 50 is juxtaposed onto thesupport plate 40 generally centrally disposed over theopen areas 41 and fixed in place by any means suitable to the material(s) employed. When the presently preferred material, titanium, is used for both components, welding (particularly spot or laser welding), an adhesive or sintering may be employed. Sintering (i.e., heating the complete assembly until the titanium components have fused at the points of abutment) has been found to give particularly good results, and, if the supplementary struts 48 and/orminor struts - When alternative materials, such as chromium cobalt alloy and Teflon-coated surgical steel, are selected, the size parameters discussed above for titanium are also suitable, and the fixation of the
fine mesh screen 50 to thesupport plate 40 may be carried out in the same manner when chromium cobalt alloy is employed. However, when Teflon-coated surgical steel is used, a compatible fixation method must be employed. For example, the Teflon coating may be first scraped away in the regions of abutment between the two components before the joining step is carried out, or a special purpose adhesive may be used. Preferably, however, the Teflon coating is more practically applied after the two-piece structure has been fabricated. - The resulting two-piece (plus supplementary and/or minor struts) guided-
tissue regeneration plate 49 shown in FIG. 21 can then be used in the process described above with notably improved results with respect to the speed and quality with which jaw bone is regenerated along a patient's bony ridge and thicker and more healthy overlying periosteum. Consequently, the long term outlook for the integrity of subsequent dental implants is correspondingly improved, a more satisfactory result having been obtained more quickly. - In order to insure a secure fixation of the two-piece guided-
tissue regeneration plate 49 to the support structure which is fixed to the jaw bone of a patient as previously described with respect to the guided-tissue regeneration plates inner support ring 43 which defines thecentral aperture 44 which functionally corresponds to theapertures inner support ring 43. More particularly, as best shown in the enlarged fragmentary cross section of FIG. 23, the thickness of the centralinner support ring 43 may be augmented by any suitable means such as by stackingadditional material 43A over thesupport ring 43 which is integral with thestruts 42 as previously described. - Preparation of a variant version of the second preferred embodiment is illustrated in FIGS.24-27. FIG. 24 shows an imperforate
monolithic plate 60 having peripheral outer dimensions corresponding to those of the guided-tissue regeneration plate 49 shown in FIG. 22. As previously mentioned, a preferred material is titanium plate having a thickness of about 0.008-0.025 of an inch and preferably about 0.012 of an inch. Theimperforate plate 60 is subjected to further processing to obtain the desired guided-tissue regeneration plate as a unitary structure. - Thus, referring now to FIG. 25, in anticipation of reducing the thickness of predetermined central regions of the
plate 60, a suitable configuredmask 61 is prepared and juxtaposed overlaying one surface of the plate. Themask 61 may be a separate stencil-like layer or may be deposited directly on the surface of theplate 60 by a conventional technique such as by depositing a photo-resist layer applied in the desired pattern; i.e., a pattern which will shield the areas of theplate 60 which are not to be reduced in thickness. Accordingly, the areas which are not coated or otherwise masked off are subject to reduction in thickness. Because the open region pattern employed in the example describing the first version of the second preferred embodiment of the guided-tissue regeneration plate has been found to work well, it is also used to describe the second version. Still referring to FIG. 25, radial struts 64 of themask 61 define a series of circumferentially distributedopenings 62 while arms adjoining adjacent radial struts 64 definesupplementary struts 65 which corresponds to the supplementary struts 48 shown in FIGS. 19, 21 and 22 and discussed above. The rectangular configuration of the supplementary struts 65 and the inner ends of the radial struts 64 defineadditional openings 67. The inner ends of the radial struts 64 each terminate at aring 66 which circumscribescentral mask opening 63. - Once the
mask 61 has been emplaced over theplate 60, the masked surface can be subjected to a conventional acid etch to remove unprotected metal and hence reduce the thickness of theplate 60 in the unmasked areas to the previously discussed range of 0.002-0.006 of an inch and preferably about 0.003 of an inch. The rate and extent of the metal removal can be controlled, as well known in the art, by selecting the type of acid, its concentration and temperature and the length of time the plate is subjected to the acid. - FIG. 26 shows the plate60A after the acid etch step has been completed. Thus, regions 68, 69, 70 will be understood to be of diminished thickness while the strut regions 71, supplementary strut regions 72, central ring region 73 and peripheral region 74 remain at the original thickness of the plate because they were protected by the mask during the etching operation.
- The second variant of the second preferred embodiment of the guided-tissue regeneration plate is competed by perforating its surface with a large number of closely spaced apertures, typically circular in shape. As shown in FIG. 27, the guided-tissue regeneration plate60B has been pierced by numerous closely spaced apertures 75 in the regions 71, 72, 73, 74 of the plate which were not reduced in thickness. In the regions 68, 69 which were reduced in thickness, the plate is pierced even more densely with numerous closely spaced apertures 76. The central aperture 70 is opened through the plate 60B during the finishing process to serve as a fixation screw receiving opening in the same manner as previously described with respect to the central aperture 44 (FIGS. 22, 23) of the two-piece first variant of the alternative preferred embodiment for the guided-tissue regeneration plate.
- The size and spacing of the apertures in both the original thickness and the reduced thickness regions of the guided-tissue regeneration plate60B affects both the porosity and the mechanical pliability of the individual regions. The spacing can be either random as shown for the majority of the areas in FIG. 27 or in a definite pattern as shown in the regions 76 (a thinned-down region) and 77 (an original thickness region—not enlarged). The regions 76 and 77 are contrasted by the use of smaller apertures and finer spacing in the reduced thickness region 76, thus achieving increased porosity. In contrast, the larger apertures and wider spacing employed in the original thickness region 77 provides a stiffer, but still compliant, structure for the peripheral region 74 which achieves a structure mechanically well-adapted for emplacement and subsequent maintenance of its position and configuration in use.
- It was noted above that one or more minor struts (e.g., the minor struts46, 47 shown in FIGS. 19, 21) may be provided as necessary to ensure sufficient rigidity to the screened portion of the first variant of the alternative preferred embodiment for the guided-tissue regeneration plate. Corresponding minor struts may also be incorporated into the second variant of the alternative preferred embodiment for the guided-tissue regeneration plate shown in FIG. 27 by either making provision for such in the
mask 61 or by later affixing them, as separate components in the manner previously described, to the unitary structure. - While the presently preferred material for either version of the alternative preferred embodiment is titanium, the use of other materials, non-resorptive and resorptive, as discussed above may be employed. As with the previously described embodiments, after the desired bone regeneration has been achieved, the variant preferred embodiment of the guided-tissue regeneration plate may be left in place or removed prior to the implantation process as may be appropriate for a given patient. Further, as also previously described with respect to the guided-
tissue regeneration plate 35, if a temporary period of isolation from epithelial cells is desired to create a membrane barrier from epithelial cells for a limited period of time which allows for the exchange of nutrients, ions, and tissue fluid or perhaps blood supply, then a resorptive barrier such as Vicryl™, collagen, resorptive hydroxyapatite crystals or Guidor™ can be applied to the top or bottom side of the guided-tissue regeneration plates 49, 60B to seal the perforations, then resorbing a limited time later after the system is installed. - A performance improving enhancement which can be employed either with the guided-tissue regeneration plate described and claimed in the aforementioned parent U.S. Pat. No. 5,839,899 or with the guided-tissue regeneration plates described and claimed herein is to decrease the surface tension, and hence increase the “wetability”, of the guided-tissue regeneration plate surfaces. This effect can be achieved in several ways. For example, subjecting the guided-tissue regeneration plate to a plasma spray or gently blasting it with fine to coarse grit abrasive or subjecting it to a suitable acid etchant for a suitable period will achieve the desired result. This slight roughening of the surface of the guided-tissue regeneration plate serves to promote better tissue adhesion and consequently decreases susceptibility to infection or exposure of the plate. In a variant of this enhancement, only the top (tissue side) of the guided-tissue regeneration plate is roughened in order that the tissue will adhere to it, yet the plate can be readily peeled away in due course from the underlying, newly-formed bone.
- Thus, while the principles of the invention have now been made clear in an illustrative embodiment, there will be immediately obvious to those skilled in the art many modifications of structure, arrangements, proportions, the elements, materials, and components, used in the practice of the invention which are particularly adapted for specific environments and operating requirements without departing from those principles.
Claims (42)
1. In apparatus for use in a method of growing bone in order to increase the volume of the bony ridge of the maxilla or mandible by creating a protected and supported space between the underside of the gum tissue and the jaw bone which is protected from outside chewing forces, muscular or tissue pressure, or any other premature loading by utilizing a guided-tissue regeneration plate support and fixation system, which method comprises:
A) fixing a support medium to the jaw bone, said support medium being configured to receive and support a guided-tissue regeneration plate;
B) juxtaposing a guided-tissue regeneration plate with respect to the jaw bone in a tent-like manner to create a protected space by affixing said guided-tissue regeneration plate to and suspending it from said support medium, which said guided-tissue regeneration plate is pliable and moldable, but keeps its shape after being molded, said guided-tissue regeneration plate being further characterized in that it is fabricated from a bio-compatible material; and
C) waiting for bone to grow in the resulting protected space; the improvement in which:
D) said guided-tissue regeneration plate comprises first and second integrated components including:
1) a first component comprising a support plate having a peripheral region and a generally open central portion; and
2) a fine mesh screen juxtaposed over said central portion of said support plate and fixed to said peripheral region thereof.
2. The apparatus of in which said support plate and said fine mesh screen are each made of a bio-compatible material selected from the group including titanium, chromium cobalt alloy and Teflon-coated surgical steel and in which said peripheral region of said support plate is perforated.
claim 1
3. The apparatus of in which said guided-tissue regeneration plate is coated with a resorptive, bio-compatible material for the purpose of creating a temporary guided-tissue regeneration plate barrier to prevent migration of epithelial cells across its surface, yet allow blood supply and/or nutrients to pass through the resorptive barrier.
claim 1
4. The apparatus of in which said guided-tissue regeneration plate is coated with a resorptive, bio-compatible material for the purpose of creating a temporary guided-tissue regeneration plate barrier to prevent migration of epithelial cells across its surface, yet allow blood supply and/or nutrients to pass through the resorptive barrier.
claim 2
5. The apparatus of in which:
claim 1
A) the thickness of said peripheral region of said support plate falls within the range of 0.008-0.025 of an inch; and
B) said fine mesh screen comprises a weave of wire in which:
1) the diameter said wire employed falls within the range of 0.002-0.006 of an inch; and
2) the weave of said wire falls within the range of 10×10 wires per inch to 200×200 wires per inch.
6. The apparatus of in which:
claim 2
A) the thickness of said peripheral region of said support plate falls within the range of 0.008-0.025 of an inch; and
B) said fine mesh screen comprises a weave of wire in which:
1) the diameter said wire employed falls within the range of 0.002-0.006 of an inch; and
2) the weave of said wire falls within the range of 10×10 wires per inch to 200×200 wires per inch.
7. The apparatus of in which:
claim 3
A) the thickness of said peripheral region of said support plate falls within the range of 0.008-0.025 of an inch; and
B) said fine mesh screen comprises a weave of wire in which:
1) the diameter said wire employed falls within the range of 0.002-0.006 of an inch; and
2) the weave of said wire falls within the range of 10×10 wires per inch to 75×75 wires per inch.
8. The apparatus of in which:
claim 4
A) the thickness of said peripheral region of said support plate falls within the range of 0.008-0.025 of an inch; and
B) said fine mesh screen comprises a weave of wire in which:
1) the diameter said wire employed falls within the range of 0.002-0.006 of an inch; and
2) the weave of said wire falls within the range of 10×10 wires per inch to 200×200 wires per inch.
9. The apparatus of in which integral struts extend from said peripheral region of said support plate into said generally open central portion thereof to provide support for said fine mesh screen.
claim 1
10. The apparatus of in which integral struts extend from said peripheral region of said support plate into said generally open central portion thereof to provide support for said fine mesh screen.
claim 2
11. The apparatus of in which integral struts extend from said peripheral region of said support plate into said generally open central portion thereof to provide support for said fine mesh screen.
claim 5
12. The apparatus of in which integral struts extend from said peripheral region of said support plate into said generally open central portion thereof to provide support for said fine mesh screen.
claim 6
13. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 1
14. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 2
15. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 5
16. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 6
17. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 9
18. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 10
19. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 11
20. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 12
21. In apparatus for use in a method of growing bone in order to increase the volume of the bony ridge of the maxilla or mandible by creating a protected and supported space between the underside of the gum tissue and the jaw bone which is protected from outside chewing forces, muscular or tissue pressure, or any other premature loading by utilizing a guided-tissue regeneration plate support and fixation system, which method comprises:
A) fixing a support medium to the jaw bone, said support medium being configured to receive and support a guided-tissue regeneration plate;
B) juxtaposing a guided-tissue regeneration plate with respect to the jaw bone in a tent-like manner to create a protected space by affixing said guided-tissue regeneration plate to and suspending it from said support medium, which said guided-tissue regeneration plate is pliable and moldable, but keeps its shape after being molded, said guided-tissue regeneration plate being further characterized in that it is fabricated from a bio-compatible material; and
C) waiting for bone to grow in the resulting protected space; the improvement in which:
D) said guided-tissue regeneration plate comprises first and second regions of a monolithic structure:
1) said first region comprising a peripheral area having a first thickness; and
2) said second region comprising a central area having a thickness which is less than that of said peripheral region, said central area being perforated with a plurality of apertures.
22. The apparatus of in which said monolithic structure is made of a bio-compatible material selected from the group including titanium, chromium cobalt alloy and Teflon-coated surgical steel and in which said peripheral region of said support plate is perforated.
claim 21
23. The apparatus of in which said guided-tissue regeneration plate is coated with a resorptive, bio-compatible material for the purpose of creating a temporary guided-tissue regeneration plate barrier to prevent migration of epithelial cells across its surface, yet allow blood supply and/or nutrients to pass through the resorptive barrier.
claim 21
24. The apparatus of in which said guided-tissue regeneration plate is coated with a resorptive, bio-compatible material for the purpose of creating a temporary guided-tissue regeneration plate barrier to prevent migration of epithelial cells across its surface, yet allow blood supply and/or nutrients to pass through the resorptive barrier.
claim 21
25. The apparatus of in which:
claim 21
A) the thickness of said peripheral area of said guided-tissue regeneration plate falls within the range of 0.008-0.025 of an inch; and
B) the thickness of said central area of said guided-tissue regeneration plate falls within the range of 0.002-0.006 of an inch.
26. The apparatus of in which:
claim 22
A) the thickness of said peripheral area of said guided-tissue regeneration plate falls within the range of 0.008-0.025 of an inch; and
B) the thickness of said central area of said guided-tissue regeneration plate falls within the range of 0.002-0.006 of an inch.
27. The apparatus of in which integral struts extend from said peripheral area of said guided-tissue regeneration plate into said central area to provide support for said central area.
claim 21
28. The apparatus of in which integral struts extend from said peripheral area of said guided-tissue regeneration plate into said central area to provide support for said central area.
claim 22
29. The apparatus of in which integral struts extend from said peripheral area of said guided-tissue regeneration plate into said central area to provide support for said central area.
claim 25
30. The apparatus of in which integral struts extend from said peripheral area of said guided-tissue regeneration plate into said central area to provide support for said central area.
claim 26
31. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 21
32. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 22
33. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 25
34. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 26
35. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 27
36. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 28
37. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 29
38. The apparatus of in which at least a plurality of said integral struts join a circular central support having an aperture therethrough for coupling with said support medium.
claim 30
39. The apparatus of in which said guided-tissue regeneration plate is fabricated by the steps of:
claim 21
A) overlaying, on a first surface of a monolithic plate, a mask conforming to the shape of said peripheral area such that only an area conforming to the shape of the central area is exposed;
B) etching the first surface of the monolithic plate in the exposed area to diminish the thickness of the monolithic plate in the exposed area; and
C) perforating the central area with a plurality of apertures.
40. The apparatus of in which the monolithic plate is a titanium plate.
claim 39
41. In apparatus for use in a method of growing bone in order to increase the volume of the bony ridge of the maxilla or mandible by creating a protected and supported space between the underside of the gum tissue and the jaw bone which is protected from outside chewing forces, muscular or tissue pressure, or any other premature loading by utilizing a guided-tissue regeneration plate support and fixation system, which method comprises:
A) juxtaposing a guided-tissue regeneration plate with respect to the jaw bone in a tent-like manner to create a protected space, which said guided-tissue regeneration plate is pliable and moldable, but keeps its shape after being molded, said guided-tissue regeneration plate being further characterized in that it is fabricated from a bio-compatible material; and
B) waiting for bone to grow in the resulting protected space; the improvement in which:
C) at least a first region of the surface of said guided-tissue regeneration plate is roughened to decrease the surface tension thereof.
42. The apparatus of in which the entire surface of said guided-tissue regeneration plate is roughened to decrease the surface tension thereof.
claim 41
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/832,491 US6394807B2 (en) | 1996-03-01 | 2001-04-10 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/609,870 US5839899A (en) | 1996-03-01 | 1996-03-01 | Method and apparatus for growing jaw bone utilizing a guided-tissue regeneration plate support and fixation system |
US09/196,915 US6238214B1 (en) | 1996-03-01 | 1998-11-20 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
US09/832,491 US6394807B2 (en) | 1996-03-01 | 2001-04-10 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/196,915 Continuation US6238214B1 (en) | 1996-03-01 | 1998-11-20 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
Publications (2)
Publication Number | Publication Date |
---|---|
US20010012607A1 true US20010012607A1 (en) | 2001-08-09 |
US6394807B2 US6394807B2 (en) | 2002-05-28 |
Family
ID=24442696
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/609,870 Expired - Fee Related US5839899A (en) | 1996-03-01 | 1996-03-01 | Method and apparatus for growing jaw bone utilizing a guided-tissue regeneration plate support and fixation system |
US09/196,915 Expired - Fee Related US6238214B1 (en) | 1996-03-01 | 1998-11-20 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
US09/832,491 Expired - Fee Related US6394807B2 (en) | 1996-03-01 | 2001-04-10 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/609,870 Expired - Fee Related US5839899A (en) | 1996-03-01 | 1996-03-01 | Method and apparatus for growing jaw bone utilizing a guided-tissue regeneration plate support and fixation system |
US09/196,915 Expired - Fee Related US6238214B1 (en) | 1996-03-01 | 1998-11-20 | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants |
Country Status (3)
Country | Link |
---|---|
US (3) | US5839899A (en) |
AU (1) | AU2193197A (en) |
WO (1) | WO1997031586A1 (en) |
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003048347A1 (en) * | 2001-12-05 | 2003-06-12 | Karmon, Ben-Zion | Periosteal distraction |
US20030114857A1 (en) * | 2001-12-15 | 2003-06-19 | Carchidi Joseph Edward | Maxillofacial anchoring system for alveolar and small bone skeletal distraction |
US20040161725A1 (en) * | 2003-02-13 | 2004-08-19 | Clement Milton A. | Dental implantation system, support, and related methods |
US20050033427A1 (en) * | 2003-06-13 | 2005-02-10 | Freilich Martin Allen | Structural/biological implant system |
US20050059864A1 (en) * | 2001-12-05 | 2005-03-17 | Ophir Fromovich | Periosteal distraction |
US20080057472A1 (en) * | 2006-08-30 | 2008-03-06 | Clement Milton A | Dental fixture implantation system and associated method |
WO2009118725A1 (en) * | 2008-03-23 | 2009-10-01 | Shay Kahana | Tooth socket covering |
US20100291508A1 (en) * | 2009-05-13 | 2010-11-18 | Jensen Ole T | Biocompatible shell for bone treatment |
JP2010284248A (en) * | 2009-06-10 | 2010-12-24 | Platon Japan:Kk | Guided bone regeneration auxiliary device for implant |
KR101144154B1 (en) | 2011-12-16 | 2012-05-09 | 박기봉 | Artificial bone fixing device for implant |
US8226409B1 (en) | 2010-06-29 | 2012-07-24 | Armen Karapetyan | Method and device for dental implant installation |
US8298292B2 (en) | 2003-04-16 | 2012-10-30 | Howmedica Osteonics Corp. | Craniofacial implant |
US8398720B2 (en) | 2003-04-16 | 2013-03-19 | Orthovita, Inc. | Craniofacial implant |
US8814565B1 (en) | 2011-11-21 | 2014-08-26 | Armen Karapetyan | Surgical device for dental implant installation |
WO2015030228A1 (en) * | 2013-09-02 | 2015-03-05 | 株式会社ラステック | Porous plate for medical use and production method for porous plate for medical use |
US9044195B2 (en) | 2013-05-02 | 2015-06-02 | University Of South Florida | Implantable sonic windows |
US9744057B2 (en) | 2000-05-09 | 2017-08-29 | Ben-Zion Karmon | Device to deliver flowable material to the sinus |
KR20200025055A (en) * | 2018-08-29 | 2020-03-10 | 연세대학교 산학협력단 | BARRIER MEMBRANE FOR DENTAl GUIDED BONE REGENERATION HAVING COUPLING PROJECTION |
US11045289B2 (en) | 2015-12-29 | 2021-06-29 | Ben Zion Karmon | Devices and methods for elevating the Schneiderian membrane |
US20210259814A1 (en) * | 2020-02-25 | 2021-08-26 | Nanobiosystem Co., Ltd. | Periodontal tissue regeneration inducer and apparatus and method for manufacturing the same |
US11452583B2 (en) * | 2019-01-10 | 2022-09-27 | Paramvir Singh | Dental implant evaluation unit |
US11540900B2 (en) | 2018-05-03 | 2023-01-03 | The United States Of America As Represented By The Secretary Of The Navy | Dental ridge augmentation matrix with integrated dental implant surgical drill guide system |
EP4144323A4 (en) * | 2020-04-29 | 2023-09-27 | Megagen Implant Co., Ltd. | Dental membrane and dental membrane set comprising same |
US11819380B2 (en) | 2016-10-13 | 2023-11-21 | Ben Zion Karmon | Devices for tissue augmentation |
Families Citing this family (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5839899A (en) * | 1996-03-01 | 1998-11-24 | Robinson; Dane Q. | Method and apparatus for growing jaw bone utilizing a guided-tissue regeneration plate support and fixation system |
US5713921A (en) * | 1996-03-29 | 1998-02-03 | Bonutti; Peter M. | Suture anchor |
US6117162A (en) * | 1996-08-05 | 2000-09-12 | Arthrex, Inc. | Corkscrew suture anchor |
US5718717A (en) | 1996-08-19 | 1998-02-17 | Bonutti; Peter M. | Suture anchor |
WO1999029254A1 (en) * | 1997-12-10 | 1999-06-17 | Douglas Alan Schappert | Integrated guided-tissue-regeneration barrier for root-form dental implants |
US6045551A (en) | 1998-02-06 | 2000-04-04 | Bonutti; Peter M. | Bone suture |
US6257890B1 (en) * | 1998-07-10 | 2001-07-10 | Friadent Gmbh | Gingiva former |
FR2787698B1 (en) | 1998-10-27 | 2001-05-18 | Obl | INTRAORAL MANDIBULAR DISTRACTOR |
US6328765B1 (en) * | 1998-12-03 | 2001-12-11 | Gore Enterprise Holdings, Inc. | Methods and articles for regenerating living tissue |
US6293950B1 (en) | 1999-01-15 | 2001-09-25 | Luitpold Pharmaceuticals, Inc. | Resorbable pin systems |
DE19907420B4 (en) * | 1999-02-20 | 2005-08-11 | Universität Leipzig | Subperiosteal implant system to stimulate new bone formation |
US6030218A (en) * | 1999-04-12 | 2000-02-29 | Robinson; Dane Q. | Osseo-integrated sub-periosteal implant |
US6447516B1 (en) | 1999-08-09 | 2002-09-10 | Peter M. Bonutti | Method of securing tissue |
US6368343B1 (en) | 2000-03-13 | 2002-04-09 | Peter M. Bonutti | Method of using ultrasonic vibration to secure body tissue |
US6312258B1 (en) * | 1999-08-19 | 2001-11-06 | Arthur Ashman | Kit for immediate post-extraction implantation |
US6280191B1 (en) | 1999-09-03 | 2001-08-28 | Christopher B. Gordon | Distractor suitable for permanent implantation into bone |
US6402518B1 (en) * | 1999-11-30 | 2002-06-11 | Arthur Ashman | Method and apparatus for performing ridge augmentation |
US6635073B2 (en) | 2000-05-03 | 2003-10-21 | Peter M. Bonutti | Method of securing body tissue |
US7094251B2 (en) | 2002-08-27 | 2006-08-22 | Marctec, Llc. | Apparatus and method for securing a suture |
US9138222B2 (en) | 2000-03-13 | 2015-09-22 | P Tech, Llc | Method and device for securing body tissue |
DE10026306A1 (en) * | 2000-05-26 | 2001-11-29 | Tutogen Medical Gmbh | Jawbone transplant is domed and can be bent to U-shapes and is made of spongiose, cortical or compact bone material of human or animal origin |
EP2062548B1 (en) * | 2000-05-29 | 2016-05-04 | CelGen AG | Medicinal membrane for bone regeneration |
DE10138374A1 (en) * | 2001-08-11 | 2003-03-06 | Robert Eisenburger | Dental implant and cap |
KR100402266B1 (en) * | 2001-10-16 | 2003-10-17 | 주식회사 덴티움 | Method to manufacture mesh membrane for implant operation |
US6645250B2 (en) * | 2001-10-30 | 2003-11-11 | Carl W. Schulter | Biocompatible form and method of fabrication |
JP2003135478A (en) * | 2001-11-05 | 2003-05-13 | Koseki Ika Kk | Alveolar bone extender |
US6719765B2 (en) | 2001-12-03 | 2004-04-13 | Bonutti 2003 Trust-A | Magnetic suturing system and method |
US9155544B2 (en) | 2002-03-20 | 2015-10-13 | P Tech, Llc | Robotic systems and methods |
US7775796B2 (en) * | 2002-06-10 | 2010-08-17 | Biomed Est. | Bone-adaptive surface structure |
SE522983C2 (en) * | 2002-07-25 | 2004-03-23 | Nobel Biocare Ab | Arrangements to increase the resistance to load on implants and such implants |
DE20219917U1 (en) * | 2002-12-24 | 2004-04-29 | Engelke, Wilfried, Prof. Dr.Dr.med. | Satellite implant connector for tooth implant, comprising cylindrical extension for temporary accommodation in tool insertion recess |
US20050008990A1 (en) * | 2003-02-26 | 2005-01-13 | Therics, Inc. | Method and system for repairing endosseous implants, such as with a bone graft implant |
US7497864B2 (en) | 2003-04-30 | 2009-03-03 | Marctec, Llc. | Tissue fastener and methods for using same |
US7296998B2 (en) * | 2003-09-22 | 2007-11-20 | Bartee Chaddick M | Hydrophilic high density PTFE medical barrier |
US20050074437A1 (en) | 2003-10-06 | 2005-04-07 | Domonkos Horvath | Device for the regeneration of tissue, specifically bone regeneration by means of callus distraction |
US20050192675A1 (en) * | 2004-03-01 | 2005-09-01 | Robinson Dane Q. | Device for use in stimulating bone growth |
US20080039873A1 (en) | 2004-03-09 | 2008-02-14 | Marctec, Llc. | Method and device for securing body tissue |
US20080188857A1 (en) * | 2004-09-21 | 2008-08-07 | Lars Bruce | Method and Device For Improving the Fixing of a Prosthesis |
US9463012B2 (en) | 2004-10-26 | 2016-10-11 | P Tech, Llc | Apparatus for guiding and positioning an implant |
US9173647B2 (en) | 2004-10-26 | 2015-11-03 | P Tech, Llc | Tissue fixation system |
US9271766B2 (en) | 2004-10-26 | 2016-03-01 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US20060089646A1 (en) | 2004-10-26 | 2006-04-27 | Bonutti Peter M | Devices and methods for stabilizing tissue and implants |
DE202004018461U1 (en) * | 2004-11-24 | 2005-03-10 | Heß, Thomas, Dr. | Implant cassette for fixing a root-like implant into a jawbone establishes a joint between the implant and the bone hollow or surface, and provides a protective reservoir for the bone or the bone-forming matrix |
US20060154204A1 (en) * | 2005-01-12 | 2006-07-13 | Reggie John A | Dental implants with improved loading properties |
US20060154205A1 (en) * | 2005-01-12 | 2006-07-13 | Dynamic Implants | Dental implants with improved loading properties |
US9089323B2 (en) | 2005-02-22 | 2015-07-28 | P Tech, Llc | Device and method for securing body tissue |
JP4920964B2 (en) * | 2005-12-16 | 2012-04-18 | 光則 石本 | Dental materials and composite dental materials formed using hydroxyapatite |
WO2007083670A1 (en) * | 2006-01-20 | 2007-07-26 | Nihon University | Implanter |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
US7967820B2 (en) | 2006-02-07 | 2011-06-28 | P Tech, Llc. | Methods and devices for trauma welding |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US11246638B2 (en) | 2006-05-03 | 2022-02-15 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US20080118892A1 (en) * | 2006-11-22 | 2008-05-22 | Curtis Adams | Dental implant |
US8403667B2 (en) * | 2006-11-22 | 2013-03-26 | Ch Scientific, Llc | Dental implant |
US8465283B2 (en) | 2006-11-22 | 2013-06-18 | Ch Scientific, Llc | Dental implant |
US8617185B2 (en) | 2007-02-13 | 2013-12-31 | P Tech, Llc. | Fixation device |
WO2009004070A1 (en) * | 2007-07-03 | 2009-01-08 | Vlaamse Instelling Voor Technologisch Onderzoek (Vito) | Surgical implant composed of a porous core and a dense surface layer |
EP2030596B1 (en) * | 2007-08-27 | 2019-11-27 | Medartis Holding AG | Implant for treating bones. |
EP3326589B1 (en) | 2007-12-10 | 2019-08-28 | Jeffrey R. Marcus | Intermaxillary fixation device |
ES2550758T3 (en) * | 2007-12-31 | 2015-11-12 | Jeffrey R. Marcus | Intermaxillary fixation device and method to use it |
US8371852B2 (en) * | 2008-01-21 | 2013-02-12 | Dror Michael ALLON | Implant and a method for using the same |
US8033827B2 (en) * | 2008-01-21 | 2011-10-11 | Allon Dror M | Implant and a method for using same |
DE102008015114B4 (en) * | 2008-03-20 | 2009-11-05 | Heinz Kurz Gmbh Medizintechnik | Auditory ossicle prosthesis with variable attachment surfaces |
US20090259263A1 (en) | 2008-04-11 | 2009-10-15 | Biomet Microfixation, Inc. | Apparatus and methods of fixating bone |
US8968373B2 (en) * | 2008-07-24 | 2015-03-03 | Warsaw Orthopedic, Inc. | Cortical tenting screw |
US8029284B2 (en) | 2008-09-29 | 2011-10-04 | Maxillent Ltd. | Implants, tools, and methods for sinus lift and lateral ridge augmentation |
US8662891B2 (en) | 2008-09-29 | 2014-03-04 | Maxillent Ltd. | Implants, tools, and methods for sinus lift and lateral ridge augmentation |
US7934929B2 (en) * | 2008-09-29 | 2011-05-03 | Maxillent Ltd. | Sinus lift implant |
US8388343B2 (en) * | 2008-09-29 | 2013-03-05 | Maxillent Ltd. | Implants, tools, and methods for sinus lift and bone augmentation |
US8556990B2 (en) * | 2009-02-23 | 2013-10-15 | Barry K. Bartee | Reinforced PTFE medical barriers |
EP2400899A4 (en) | 2009-02-24 | 2015-03-18 | P Tech Llc | Methods and devices for utilizing bondable materials |
US7964208B2 (en) * | 2009-02-25 | 2011-06-21 | Warsaw Orthopedic, Inc. | System and methods of maintaining space for augmentation of the alveolar ridge |
CN102458299B (en) | 2009-06-16 | 2014-12-31 | 迈柯希伦特有限公司 | Toothe implanting system |
US20110014587A1 (en) * | 2009-07-16 | 2011-01-20 | Warsaw Orthopedic, Inc. | System and methods of preserving an oral socket |
US9539068B2 (en) * | 2009-07-24 | 2017-01-10 | Warsaw Orthopedic, Inc. | Implantable screw and system for socket preservation |
KR200457226Y1 (en) | 2009-09-23 | 2011-12-09 | 주식회사 메가젠임플란트 | Dental membrane |
BE1019125A3 (en) | 2009-12-24 | 2012-03-06 | Clerck Renu De | DENTAL IMPLANT SYSTEM WITH A BOTOP BUILDING ELEMENT AND A METHOD FOR MANUFACTURING SUCH BOTOP BUILDING ELEMENT. |
US20110165536A1 (en) * | 2010-01-06 | 2011-07-07 | Rainbow Medical Ltd. | Alveolar ridge augmentation |
US9526600B2 (en) | 2010-07-20 | 2016-12-27 | Warsaw Orthopedic, Inc. | Biodegradable stents and methods for treating periodontal disease |
US8882506B2 (en) * | 2010-08-17 | 2014-11-11 | Warsaw Orthopedic, Inc. | Implant repair system and method |
ES2390766B1 (en) * | 2010-09-30 | 2014-01-17 | Biotechnology Institute, I Mas D, S.L. | OSEA CRESTA EXPANSION METHOD AND AN EXPANSOR IMPLANT TO BE USED IN THIS METHOD |
DE102010055433B4 (en) * | 2010-12-10 | 2014-07-24 | Celgen Ag | Bone screw and device for bone distraction |
US8382477B2 (en) | 2011-04-18 | 2013-02-26 | Terry B. Philibin | Healing abutment system for bone contouring |
US8470046B2 (en) | 2011-04-25 | 2013-06-25 | Warsaw Orthopedic, Inc. | Bone augmentation device and method |
FR2975893B1 (en) * | 2011-05-30 | 2013-07-12 | 3Dceram | BIOCOMPATIBLE CERAMIC REINFORCED IMPLANT AND METHOD FOR MANUFACTURING THE SAME |
CA2748750A1 (en) * | 2011-08-11 | 2013-02-11 | John David FRENCH | Cap tack bone graft device |
US8702423B2 (en) | 2011-12-08 | 2014-04-22 | Maxillent Ltd. | Cortical drilling |
CN104135963B (en) | 2011-12-23 | 2017-06-09 | 奥齿泰有限责任公司 | Tooth film |
KR101144322B1 (en) | 2011-12-23 | 2012-05-11 | 오스템임플란트 주식회사 | Dental membrane |
US20130266912A1 (en) * | 2012-04-04 | 2013-10-10 | Amos Ben-yehouda | Dental implant |
EP3400898B1 (en) * | 2012-05-10 | 2020-09-02 | Homayoun H. Zadeh | Dental devices for extraction site reconstruction |
WO2013181721A2 (en) | 2012-06-05 | 2013-12-12 | Dental Vision B.V.B.A | Method for manufacturing a template to adapt the shape of a bone defect in a jaw to a bone superstructure |
US9795467B2 (en) | 2012-07-20 | 2017-10-24 | Pavel Krastev | Apparatus and method for sinus lift procedure |
US10076377B2 (en) | 2013-01-05 | 2018-09-18 | P Tech, Llc | Fixation systems and methods |
US9517087B2 (en) | 2013-03-19 | 2016-12-13 | Javier Montejo | Bone fixation system and methods |
US8992582B1 (en) | 2013-08-26 | 2015-03-31 | Stryker Leibinger Gmbh & Co. Kg | Fixation devices and method |
US9782240B2 (en) * | 2013-11-01 | 2017-10-10 | Medintal Ltd. | Sub-periosteal extension for a dental implant |
US20150282901A1 (en) * | 2014-04-08 | 2015-10-08 | Ismael El Khouly Castilla | Maxillary Barrier Membrane |
RU2558996C1 (en) * | 2014-06-05 | 2015-08-10 | Алексей Петрович Решетников | Method for eliminating insufficiency of soft tissues surrounding implanted graft |
KR102117964B1 (en) * | 2015-01-28 | 2020-06-02 | 주식회사 네오바이오텍 | Fixing body or fixing body assembly for barrier membrane |
US9730773B2 (en) | 2015-04-22 | 2017-08-15 | Maxillent Ltd. | Bone graft injection methods |
US10058393B2 (en) | 2015-10-21 | 2018-08-28 | P Tech, Llc | Systems and methods for navigation and visualization |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3849805A (en) * | 1972-11-01 | 1974-11-26 | Attending Staff Ass Los Angele | Bone induction in an alloplastic tray |
US4531916A (en) * | 1983-07-08 | 1985-07-30 | W. L. Gore & Associates, Inc. | Dental implant with expanded PTFE gingival interface |
US4636215A (en) * | 1984-01-11 | 1987-01-13 | Rei, Inc. | Combination tray and condylar prosthesis for mandibular reconstruction and the like |
US5071351A (en) * | 1986-07-02 | 1991-12-10 | Collagen Corporation | Dental implant system |
SE459152B (en) * | 1986-11-06 | 1989-06-12 | Dan Lundgren | INTRAALVOLATED IMPLANT |
US4787906A (en) * | 1987-03-02 | 1988-11-29 | Haris Andras G | Controlled tissue growth and graft containment |
DE3708638A1 (en) * | 1987-03-17 | 1988-09-29 | Grafelmann Hans L | SELF-CUTTING SCREW-IN BONE IMPLANT FOR DENTAL PURPOSES |
US4961707A (en) * | 1987-12-22 | 1990-10-09 | University Of Florida | Guided periodontal tissue regeneration |
US5700479A (en) * | 1988-12-23 | 1997-12-23 | Guidor Ab | Surgical element and method for selective tissue regeneration |
FR2647665B1 (en) * | 1989-05-30 | 1991-09-20 | Bousquet Philippe | FIXING DEVICE FOR SURGICAL USE, PARTICULARLY FOR PERFORMING GINGIVAL GRAFTS, ANCHORING ROD IN PARTICULAR NAIL FOR USE IN THIS DEVICE AND APPARATUS FOR SURGICAL IMPLANTATION OF SUCH NAILS |
CH679117A5 (en) * | 1989-06-14 | 1991-12-31 | Straumann Inst Ag | Implant in jaw-bone hole for holding bone formation around implant - has holder securing sleeve to cover hole mouth and adjacent jaw-bone area |
SE463392B (en) * | 1989-09-15 | 1990-11-19 | Nobelpharma Ab | THE DISTANCE ORGANIZATION OF A KEKBENSFOER ANCHORED DENTAL IMPLANT |
SE9100610D0 (en) * | 1991-03-04 | 1991-03-04 | Procordia Ortech Ab | BIORESORBABLE MATERIAL FOR MEDICAL USE |
DE59201996D1 (en) * | 1991-03-11 | 1995-06-01 | Straumann Inst Ag | Tools for attaching and holding a cover on a jawbone. |
US5297563A (en) * | 1992-04-03 | 1994-03-29 | Syers Charles S | Guided bone and tissue generation device and method to be used during or after dental surgery or jaw surgery |
US5511565A (en) * | 1992-04-03 | 1996-04-30 | Syers; Charles S. | Guided bone and tissue generation device and method to be used during or after dental surgery or jaw surgery |
US5372503A (en) * | 1993-04-27 | 1994-12-13 | Dental Marketing Specialists, Inc. | Method for installation of a dental implant |
US5397235A (en) * | 1993-07-02 | 1995-03-14 | Dental Marketing Specialists, Inc. | Method for installation of dental implant |
US5378152A (en) * | 1992-05-01 | 1995-01-03 | Dental Marketing Specialists, Inc. | Method and apparatus for installation of dental implant |
NL9201973A (en) * | 1992-06-11 | 1994-01-03 | Lolke Johan Van Dijk | BIO-RESORABLE BARRIER ELEMENT. |
WO1994003121A1 (en) * | 1992-08-05 | 1994-02-17 | Guidor Ab | Surgical element and method for selective tissue regeneration |
DE4232511C2 (en) * | 1992-09-29 | 1997-03-13 | Uwe Dr Blunck | Device for the implantation of artificial tooth roots |
BE1007032A3 (en) * | 1993-04-28 | 1995-02-21 | Ceka Nv | METHOD FOR MANUFACTURING A MEMBRANE FOR GUIDED BONE REGENERATION |
US5380328A (en) * | 1993-08-09 | 1995-01-10 | Timesh, Inc. | Composite perforated implant structures |
SE501733C2 (en) * | 1993-12-09 | 1995-05-02 | Nobelpharma Ab | Device for promoting bone growth |
US5489305A (en) * | 1994-10-03 | 1996-02-06 | Timesh, Inc. | Mandibular prostheses |
US5839899A (en) * | 1996-03-01 | 1998-11-24 | Robinson; Dane Q. | Method and apparatus for growing jaw bone utilizing a guided-tissue regeneration plate support and fixation system |
AT403002B (en) * | 1996-05-29 | 1997-10-27 | Mke Metall Kunststoffwaren | FILM OR MEMBRANE FOR COVERING BONE DEFECTS, METHOD FOR PRODUCING THE FILM AND NAIL FOR FIXING THE POSITION OF SUCH A FILM |
US5727945A (en) * | 1996-08-26 | 1998-03-17 | Dannenbaum; Richard M. | Impregnated barrier and method of assisting bone or tissue regeneration |
JP2001512348A (en) * | 1997-02-25 | 2001-08-21 | ノーベル バイオケア アクティエボラーグ | Bone fixation element |
WO1999029254A1 (en) * | 1997-12-10 | 1999-06-17 | Douglas Alan Schappert | Integrated guided-tissue-regeneration barrier for root-form dental implants |
US6030218A (en) * | 1999-04-12 | 2000-02-29 | Robinson; Dane Q. | Osseo-integrated sub-periosteal implant |
-
1996
- 1996-03-01 US US08/609,870 patent/US5839899A/en not_active Expired - Fee Related
-
1997
- 1997-02-28 WO PCT/US1997/003167 patent/WO1997031586A1/en active Application Filing
- 1997-02-28 AU AU21931/97A patent/AU2193197A/en not_active Abandoned
-
1998
- 1998-11-20 US US09/196,915 patent/US6238214B1/en not_active Expired - Fee Related
-
2001
- 2001-04-10 US US09/832,491 patent/US6394807B2/en not_active Expired - Fee Related
Cited By (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9744057B2 (en) | 2000-05-09 | 2017-08-29 | Ben-Zion Karmon | Device to deliver flowable material to the sinus |
US7396232B2 (en) * | 2001-12-05 | 2008-07-08 | Ophir Fromovich | Periosteal distraction |
US20050059864A1 (en) * | 2001-12-05 | 2005-03-17 | Ophir Fromovich | Periosteal distraction |
WO2003048347A1 (en) * | 2001-12-05 | 2003-06-12 | Karmon, Ben-Zion | Periosteal distraction |
US20030114857A1 (en) * | 2001-12-15 | 2003-06-19 | Carchidi Joseph Edward | Maxillofacial anchoring system for alveolar and small bone skeletal distraction |
US6887275B2 (en) * | 2001-12-15 | 2005-05-03 | Ace Surgical Supply Co., Inc. | Maxillofacial anchoring system for alveolar and small bone skeletal distraction |
US20040161725A1 (en) * | 2003-02-13 | 2004-08-19 | Clement Milton A. | Dental implantation system, support, and related methods |
US8398720B2 (en) | 2003-04-16 | 2013-03-19 | Orthovita, Inc. | Craniofacial implant |
US8298292B2 (en) | 2003-04-16 | 2012-10-30 | Howmedica Osteonics Corp. | Craniofacial implant |
EP1631321A4 (en) * | 2003-06-13 | 2008-10-29 | Univ Connecticut | Structural/biological implant system |
US8986381B2 (en) | 2003-06-13 | 2015-03-24 | University Of Connecticut | Structural/biological implant system |
US20090117519A1 (en) * | 2003-06-13 | 2009-05-07 | University Of Connecticut | Structural/biological implant system |
US20050033427A1 (en) * | 2003-06-13 | 2005-02-10 | Freilich Martin Allen | Structural/biological implant system |
EP1631321A2 (en) * | 2003-06-13 | 2006-03-08 | University of Connecticut | Structural/biological implant system |
AU2004264835B2 (en) * | 2003-06-13 | 2009-10-29 | University Of Connecticut | Structural/biological implant system |
JP2007500585A (en) * | 2003-06-13 | 2007-01-18 | ザ・ユニバ−シティ・オブ・コネチカット | Structural / biological implant systems |
US8152848B2 (en) | 2003-06-13 | 2012-04-10 | University Of Connecticut | Structural/biological implant system |
US7530810B2 (en) | 2006-08-30 | 2009-05-12 | Clement Milton A | Dental fixture implantation system and associated method |
US20080057472A1 (en) * | 2006-08-30 | 2008-03-06 | Clement Milton A | Dental fixture implantation system and associated method |
WO2009118725A1 (en) * | 2008-03-23 | 2009-10-01 | Shay Kahana | Tooth socket covering |
US20100291508A1 (en) * | 2009-05-13 | 2010-11-18 | Jensen Ole T | Biocompatible shell for bone treatment |
JP2010284248A (en) * | 2009-06-10 | 2010-12-24 | Platon Japan:Kk | Guided bone regeneration auxiliary device for implant |
US8226409B1 (en) | 2010-06-29 | 2012-07-24 | Armen Karapetyan | Method and device for dental implant installation |
US8814565B1 (en) | 2011-11-21 | 2014-08-26 | Armen Karapetyan | Surgical device for dental implant installation |
KR101144154B1 (en) | 2011-12-16 | 2012-05-09 | 박기봉 | Artificial bone fixing device for implant |
US9044195B2 (en) | 2013-05-02 | 2015-06-02 | University Of South Florida | Implantable sonic windows |
JP6082816B2 (en) * | 2013-09-02 | 2017-02-15 | 株式会社ラステック | Medical perforated plate and medical perforated plate manufacturing method |
EP3042629A1 (en) * | 2013-09-02 | 2016-07-13 | Fukushima Medical University | Porous plate for medical use and production method for porous plate for medical use |
EP3042629A4 (en) * | 2013-09-02 | 2017-03-29 | Fukushima Medical University | Porous plate for medical use and production method for porous plate for medical use |
WO2015030228A1 (en) * | 2013-09-02 | 2015-03-05 | 株式会社ラステック | Porous plate for medical use and production method for porous plate for medical use |
US10213239B2 (en) | 2013-09-02 | 2019-02-26 | Fukushima Medical University | Porous plate for medical use and manufacturing method of porous plate for medical use |
US11045289B2 (en) | 2015-12-29 | 2021-06-29 | Ben Zion Karmon | Devices and methods for elevating the Schneiderian membrane |
US11819380B2 (en) | 2016-10-13 | 2023-11-21 | Ben Zion Karmon | Devices for tissue augmentation |
US11540900B2 (en) | 2018-05-03 | 2023-01-03 | The United States Of America As Represented By The Secretary Of The Navy | Dental ridge augmentation matrix with integrated dental implant surgical drill guide system |
KR102146161B1 (en) | 2018-08-29 | 2020-08-19 | 연세대학교 산학협력단 | BARRIER MEMBRANE FOR DENTAl GUIDED BONE REGENERATION HAVING COUPLING PROJECTION |
KR20200025055A (en) * | 2018-08-29 | 2020-03-10 | 연세대학교 산학협력단 | BARRIER MEMBRANE FOR DENTAl GUIDED BONE REGENERATION HAVING COUPLING PROJECTION |
US11452583B2 (en) * | 2019-01-10 | 2022-09-27 | Paramvir Singh | Dental implant evaluation unit |
US20220401190A1 (en) * | 2019-01-10 | 2022-12-22 | Paramvir Singh | Dental implant evaluation unit |
US20210259814A1 (en) * | 2020-02-25 | 2021-08-26 | Nanobiosystem Co., Ltd. | Periodontal tissue regeneration inducer and apparatus and method for manufacturing the same |
EP4144323A4 (en) * | 2020-04-29 | 2023-09-27 | Megagen Implant Co., Ltd. | Dental membrane and dental membrane set comprising same |
Also Published As
Publication number | Publication date |
---|---|
US6394807B2 (en) | 2002-05-28 |
US5839899A (en) | 1998-11-24 |
AU2193197A (en) | 1997-09-16 |
WO1997031586A1 (en) | 1997-09-04 |
US6238214B1 (en) | 2001-05-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6238214B1 (en) | Guided tissue regeneration plate for use in a process for growing jaw bone in anticipation of performing dental implants | |
US4872840A (en) | Dental implant and method | |
US5769637A (en) | Dental implant and alveolar process augmentation structures and method of installation | |
WO1997043978B1 (en) | Dental implant and alveolar process augmentation structures and method of installation | |
US5306149A (en) | Implant for attaching a substitute tooth or the like to a jaw | |
KR100909912B1 (en) | Implants for use on the aesthetics of the mouth | |
EP2793734B1 (en) | Dental device for enhancing bone growth | |
US5433607A (en) | Implant for attaching a substitute tooth or the like to a jaw | |
US20050192675A1 (en) | Device for use in stimulating bone growth | |
US5004422A (en) | Oral endosteal implants and a process for preparing and implanting them | |
JPH05505952A (en) | Methods and devices for efficiently fixing grafts and promoting bone tissue growth | |
AU8233787A (en) | Intraalveolar implant | |
DE4040872C2 (en) | Dental implant | |
Balshi et al. | Treatment of osseous defects using vicryl mesh (polyglactin 910) and the Brånemark implant: a case report | |
DE3444780A1 (en) | Dental implant | |
DE3034086C2 (en) | Anchoring device for fastening teeth or dentures | |
JP2021023829A (en) | Dental implant of 2-pieces type | |
WO2005092236A1 (en) | Biomechanical implant | |
JPH0564646A (en) | Implant set | |
KR20190043697A (en) | Abutment for implant | |
US20230210639A1 (en) | Dental support screw | |
JPH02161939A (en) | Artificial tooth root | |
WO1993013728A1 (en) | Method of installing a dental implant | |
JPH10211218A (en) | Fixture for dental implant | |
Gardella et al. | Guided bone regeneration, autogenous bone graft: limits and indications |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FPAY | Fee payment |
Year of fee payment: 4 |
|
SULP | Surcharge for late payment | ||
REMI | Maintenance fee reminder mailed | ||
REMI | Maintenance fee reminder mailed | ||
LAPS | Lapse for failure to pay maintenance fees | ||
STCH | Information on status: patent discontinuation |
Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
|
FP | Lapsed due to failure to pay maintenance fee |
Effective date: 20100528 |