US20010034507A1 - Injection device - Google Patents

Injection device Download PDF

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Publication number
US20010034507A1
US20010034507A1 US09/888,669 US88866901A US2001034507A1 US 20010034507 A1 US20010034507 A1 US 20010034507A1 US 88866901 A US88866901 A US 88866901A US 2001034507 A1 US2001034507 A1 US 2001034507A1
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United States
Prior art keywords
sleeve
injection device
dose
shaft
stepped member
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Granted
Application number
US09/888,669
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US6383167B2 (en
Inventor
Fritz Kirchhofer
Peter Michel
Birger Hjertman
Gustav Levander
Olle Ljungquist
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Tecpharma Licensing AG
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Individual
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Assigned to TECPHARMA LICENSING AG reassignment TECPHARMA LICENSING AG CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: DISETRONIC SERVICES AG
Assigned to DISETRONIC SERVICES AG reassignment DISETRONIC SERVICES AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DISETRONIC LICENSING AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31563—Mechanically operated dose setting member interacting with a displaceable stop member

Definitions

  • the invention relates to an injection device for injecting a selectable dose of a liquid substance from an ampoule located in an ampoule holder, comprising a sleeve-shaped mechanism holder mechanically coupled thereto, in the interior of the mechanism holder a longitudinally shiftable shaft with a piston disposed thereon being provided which acts on the ampoule, wherein the shaft being surrounded by an also longitudinally shiftable advancing sleeve, mechanically coupled thereto, which in its upper end area is closed by a lid.
  • Such an injection device is known from EP 0 373 321 B 1 that consists of an ampoule sleeve for receiving the ampoule and a delivering mechanism.
  • this is composed of a cylindrical piston shaft with an inner hollow cylinder and an outer hollow cylinder which is formed in one piece with this and which exhibits a guiding cam on its outer shell.
  • a dosing ring is fixed radially to the outer hollow cylinder. The dosing can be read off by means of a scaling fastened to the outer perimeter of the dosing ring through a sight glass set into the housing of the mechanism holder.
  • the delivering mechanism is disposed longitudinally movably in the mechanism holder by means of a retaining spring and secured by a lid screwable into the housing of the mechanism holder.
  • the dosing ring rests against the lid with the force of the retaining spring.
  • the housing of the mechanism holder is provided on its inside with elongated slots of different length in which the corresponding guiding cam of the delivering mechanism is able to glide. As a result, the lift of the delivering mechanism is determined by the length of the elongated slot cooperating with the guiding cam.
  • a special-purpose wrench is necessary, by means of which an interlocking ring of the device can be unlocked until the guiding cam of the delivering mechanism is released from the respective elongated slot. The physician is then able to select the desired dose by rotation of the released delivering mechanism and renewed catch of the guiding cam into a corresponding elongated slot.
  • the injection device can only be used for delivering a single dose although possibly a sufficient supply of medicine is still available in the ampoule.
  • the ampoule sleeve In order to administer another dose of medicine, the ampoule sleeve must be unlocked from the mechanism holder and disposed of together with the ampoule possibly still containing medicine.
  • An injection device of generic type is known from EP 0 037 696 B 1 with which a dose of a liquid substance to be administered can be taken from an ampoule via a transmission mechanism of tractive force acting in one direction upon operating a locking cap.
  • the transmission mechanism of tractive force consists in that one pushing part is equipped with a plurality of teeth and the other pushing part with a pawl, which intermesh and therefore effect the advance of the transmission mechanism of tractive force only in one direction of ejection of the dose to be administered.
  • the maximum lift height and therefore the maximum dose to be administered is limited via a notch and a stop.
  • the operator of the injection device is also able to select less than the maximum dose by listening to the number of clicks which occur when, during the advance, the teeth of the pushing part catch in the pawl. In this connection, one click corresponds to the minimum dose.
  • the operating element, the locking cap is pushed back up to a stop by means of a spring.
  • This injection device is designed for extremely careful operation since a click can easily be overheard and different doses to be administered not be securely adjusted. In addition, no display unit is foreseen for the dose to be selected.
  • the present invention is therefore based on the problem to identify an injection device of the type described above which is simple in the constructive design and simple in the handling and with which the operator himself by simple movements is safely able to select the dose to be administered.
  • a dosing sleeve with a stepped member is provided for selecting a dose of a liquid substance to be injected, which is disposed on the mechanism holder in its upper end area, wherein the dose to be respectively administered being adjustable by a rotation of the dosing sleeve with the stepped member.
  • the dosing sleeve is composed of an operating element with a profile, an adjoining cylinder with dose imprint, a catch stop, and the stepped member adjoining this.
  • the constructive coupling of the dosing sleeve to the injection device is thereby characterized in that together with the stepped member and the cylinder with the dose imprint it surrounds the advancing sleeve.
  • the injection device according to the invention has the fundamental advantage that a dose, adjusted once, can be applied repeatedly; the user just has to load the injection device before each injection.
  • the selection of the dose to be applied is quite easy due to a simple rotation of the dosing sleeve.
  • FIG. 1 the injection device according to the invention in section
  • FIG. 2 the dosing sleeve with stepped member in a perspective view
  • FIG. 3 a section along the line A-A in FIG. 1.
  • the injection device shown in FIG. 1 consists of the ampoule holder 1 in which the ampoule 2 with the piston 12 and with the liquid substance to be administered are located.
  • the sleeve-shaped mechanism holder 3 is mechanically coupled to the ampoule holder 1 by a thread or another suitable lock such as a bayonet lock.
  • the longitudinally shiftable shaft 4 is disposed acting on the piston 12 of the ampoule 2 .
  • the shaft 4 is surrounded by the also longitudinally shiftable advancing sleeve 5 mechanically coupled thereto, which is closed in its upper end area by the lid 7 .
  • the dosing sleeve 6 with the stepped member 13 is provided which is arranged on the mechanism holder 3 in its upper end area.
  • the dosing sleeve 6 with the stepped member 13 surrounds the advancing sleeve 5 .
  • the dose to be respectively adjusted and to be administered is selectable by a simple rotation of the dosing sleeve 6 with the stepped member 13 .
  • the dosing sleeve 6 is mechanically coupled to the mechanism holder 3 via the catch stop 14 .
  • the dosing sleeve 6 consists, according to FIG.
  • the cam 8 is disposed on the advancing sleeve 5 , which upon withdrawing the advancing sleeve 5 in the direction of the lid 7 comes to a stop against the step of the stepped member 13 respectively adjusted. Upon pressing down the advancing sleeve 5 , the cam 8 comes to a stop against the shoulder 18 of the mechanism holder 3 , resulting in the injection lift X.
  • the shaft 4 is provided with the toothing 17 which cooperates with the locking cam 10 of the advancing sleeve 5 .
  • the depth of tooth of the toothings 17 on the shaft 4 corresponds to the step height of the stepped member 13 .
  • the mechanism holder 3 comprises the catch 11 which also cooperates with the toothing 17 of the shaft 4 .
  • the dose imprint on the cylinder 15 is visible via a window 9 in the mechanism holder 3 .
  • the mechanism holder 3 comprises a plurality of bulges 19 into which the projections 20 of the stepped member 13 catch. (FIG. 3)
  • the shaft 4 is non-rotatably longitudinally shiftable.
  • FIG. 1 shows this before the loading.
  • the advancing sleeve 5 is pulled upward by the lid 7 , mechanically coupled thereto, until the cam 8 which is part of the advancing sleeve 5 comes to a stop against the currently adjusted step of the stepped member 13 .
  • the locking cam 10 of the advancing sleeve 5 glides over the toothing 17 of the shaft 4 , the teeth of which (not shown) are arrow-shaped downward.
  • the catch 11 is provided on the mechanism holder 3 which is not shiftable longitudinally.
  • the catch 11 braces itself into the toothing 17 and prevents motion of the shaft 4 upward.
  • pressure in the downward direction is exerted by the operator on the lid 7 and on the advancing sleeve 5 coupled thereto.
  • the locking cam 10 braces itself into the toothing 17 and, so to say, takes the shaft 4 along and the piston 12 coupled to the shaft 4 exerts pressure on the ampoule 2 located in the ampoule holder 1 , with which the liquid substance is applied by administering it through an injection needle (not shown).

Abstract

The invention relates to an injection device for injecting a selectable dose of a liquid substance from an ampoule (2), located in an ampoule holder (1), comprising a piston (12) and a sleeve-shaped mechanism holder (3), mechanically coupled thereto, in the interior of which a longitudinally shiftable shaft (4) is provided which acts on the ampoule (2), the shaft (4) being surrounded by an also longitudinally shiftable advancing sleeve (5), mechanically coupled thereto, which in its upper end area is closed by a lid (7). For selecting a dose of the liquid substance to be injected, a dosing sleeve (6) with a stepped member (13) is provided, which is disposed on the mechanism holder (3) in its upper end area, the dose to be respectively administered being adjustable by a rotation of the dosing sleeve (6) with the stepped member (13).

Description

  • The invention relates to an injection device for injecting a selectable dose of a liquid substance from an ampoule located in an ampoule holder, comprising a sleeve-shaped mechanism holder mechanically coupled thereto, in the interior of the mechanism holder a longitudinally shiftable shaft with a piston disposed thereon being provided which acts on the ampoule, wherein the shaft being surrounded by an also longitudinally shiftable advancing sleeve, mechanically coupled thereto, which in its upper end area is closed by a lid. [0001]
  • Such an injection device is known from EP 0 373 321 [0002] B 1 that consists of an ampoule sleeve for receiving the ampoule and a delivering mechanism. In turn, this is composed of a cylindrical piston shaft with an inner hollow cylinder and an outer hollow cylinder which is formed in one piece with this and which exhibits a guiding cam on its outer shell. A dosing ring is fixed radially to the outer hollow cylinder. The dosing can be read off by means of a scaling fastened to the outer perimeter of the dosing ring through a sight glass set into the housing of the mechanism holder. The delivering mechanism is disposed longitudinally movably in the mechanism holder by means of a retaining spring and secured by a lid screwable into the housing of the mechanism holder. The dosing ring rests against the lid with the force of the retaining spring. The housing of the mechanism holder is provided on its inside with elongated slots of different length in which the corresponding guiding cam of the delivering mechanism is able to glide. As a result, the lift of the delivering mechanism is determined by the length of the elongated slot cooperating with the guiding cam. The adaptation of the dose to be administered to the needs of a patient takes place exclusively by an authorized person, e.g. a physician. A special-purpose wrench is necessary, by means of which an interlocking ring of the device can be unlocked until the guiding cam of the delivering mechanism is released from the respective elongated slot. The physician is then able to select the desired dose by rotation of the released delivering mechanism and renewed catch of the guiding cam into a corresponding elongated slot.
  • Once selected, the dose cannot be varied without considerable effort. In addition, based on the construction of the delivering mechanism, the injection device can only be used for delivering a single dose although possibly a sufficient supply of medicine is still available in the ampoule. In order to administer another dose of medicine, the ampoule sleeve must be unlocked from the mechanism holder and disposed of together with the ampoule possibly still containing medicine. [0003]
  • An injection device of generic type is known from EP 0 037 696 [0004] B 1 with which a dose of a liquid substance to be administered can be taken from an ampoule via a transmission mechanism of tractive force acting in one direction upon operating a locking cap. The transmission mechanism of tractive force consists in that one pushing part is equipped with a plurality of teeth and the other pushing part with a pawl, which intermesh and therefore effect the advance of the transmission mechanism of tractive force only in one direction of ejection of the dose to be administered. The maximum lift height and therefore the maximum dose to be administered is limited via a notch and a stop. The operator of the injection device is also able to select less than the maximum dose by listening to the number of clicks which occur when, during the advance, the teeth of the pushing part catch in the pawl. In this connection, one click corresponds to the minimum dose. The operating element, the locking cap, is pushed back up to a stop by means of a spring.
  • This injection device is designed for extremely careful operation since a click can easily be overheard and different doses to be administered not be securely adjusted. In addition, no display unit is foreseen for the dose to be selected. [0005]
  • The present invention is therefore based on the problem to identify an injection device of the type described above which is simple in the constructive design and simple in the handling and with which the operator himself by simple movements is safely able to select the dose to be administered. [0006]
  • This problem is thereby solved in that a dosing sleeve with a stepped member is provided for selecting a dose of a liquid substance to be injected, which is disposed on the mechanism holder in its upper end area, wherein the dose to be respectively administered being adjustable by a rotation of the dosing sleeve with the stepped member. [0007]
  • In this case, the dosing sleeve is composed of an operating element with a profile, an adjoining cylinder with dose imprint, a catch stop, and the stepped member adjoining this. The constructive coupling of the dosing sleeve to the injection device is thereby characterized in that together with the stepped member and the cylinder with the dose imprint it surrounds the advancing sleeve. [0008]
  • The injection device according to the invention has the fundamental advantage that a dose, adjusted once, can be applied repeatedly; the user just has to load the injection device before each injection. The selection of the dose to be applied is quite easy due to a simple rotation of the dosing sleeve. [0009]
  • Further advantageous embodiments of the invention can be taken from the dependent claims.[0010]
  • One embodiment of the invention is represented in the figures. [0011]
  • It is shown in: [0012]
  • FIG. 1: the injection device according to the invention in section; [0013]
  • FIG. 2: the dosing sleeve with stepped member in a perspective view; [0014]
  • FIG. 3: a section along the line A-A in FIG. 1.[0015]
  • The injection device shown in FIG. 1 consists of the [0016] ampoule holder 1 in which the ampoule 2 with the piston 12 and with the liquid substance to be administered are located. The sleeve-shaped mechanism holder 3 is mechanically coupled to the ampoule holder 1 by a thread or another suitable lock such as a bayonet lock. In the interior of the mechanism holder 3, the longitudinally shiftable shaft 4 is disposed acting on the piston 12 of the ampoule 2. The shaft 4 is surrounded by the also longitudinally shiftable advancing sleeve 5 mechanically coupled thereto, which is closed in its upper end area by the lid 7. For selecting a dose of the liquid substance to be injected, the dosing sleeve 6 with the stepped member 13 is provided which is arranged on the mechanism holder 3 in its upper end area. In this case, the dosing sleeve 6 with the stepped member 13 surrounds the advancing sleeve 5. The dose to be respectively adjusted and to be administered is selectable by a simple rotation of the dosing sleeve 6 with the stepped member 13. The dosing sleeve 6 is mechanically coupled to the mechanism holder 3 via the catch stop 14. The dosing sleeve 6 consists, according to FIG. 2, of the profiled operating element 16, the adjoining cylinder 15 with the dose imprint, the catch stop 14, and the stepped member 13 adjoining this. The cam 8 is disposed on the advancing sleeve 5, which upon withdrawing the advancing sleeve 5 in the direction of the lid 7 comes to a stop against the step of the stepped member 13 respectively adjusted. Upon pressing down the advancing sleeve 5, the cam 8 comes to a stop against the shoulder 18 of the mechanism holder 3, resulting in the injection lift X.
  • For mechanical coupling of [0017] shaft 4 with the advancing sleeve 5 the shaft 4 is provided with the toothing 17 which cooperates with the locking cam 10 of the advancing sleeve 5. In this case, the depth of tooth of the toothings 17 on the shaft 4 corresponds to the step height of the stepped member 13. In the area of its lower end, the mechanism holder 3 comprises the catch 11 which also cooperates with the toothing 17 of the shaft 4. The dose imprint on the cylinder 15 is visible via a window 9 in the mechanism holder 3. In its interior, the mechanism holder 3 comprises a plurality of bulges 19 into which the projections 20 of the stepped member 13 catch. (FIG. 3) The shaft 4 is non-rotatably longitudinally shiftable.
  • The mode of operation of the injection device according to the invention is as follows: [0018]
  • The operator turns the [0019] dosing sleeve 6 with the stepped member 13 until the desired dose imprint on the cylinder appears in the window 9. Then, the injection device is loaded. FIG. 1 shows this before the loading. For the loading, the advancing sleeve 5 is pulled upward by the lid 7, mechanically coupled thereto, until the cam 8 which is part of the advancing sleeve 5 comes to a stop against the currently adjusted step of the stepped member 13. In this case, the locking cam 10 of the advancing sleeve 5 glides over the toothing 17 of the shaft 4, the teeth of which (not shown) are arrow-shaped downward. In order to prevent that the shaft 4 is nevertheless shifted upward at the same time, the catch 11 is provided on the mechanism holder 3 which is not shiftable longitudinally. Thus, the catch 11 braces itself into the toothing 17 and prevents motion of the shaft 4 upward. For administering the selected dose, pressure in the downward direction is exerted by the operator on the lid 7 and on the advancing sleeve 5 coupled thereto. In this case, the locking cam 10 braces itself into the toothing 17 and, so to say, takes the shaft 4 along and the piston 12 coupled to the shaft 4 exerts pressure on the ampoule 2 located in the ampoule holder 1, with which the liquid substance is applied by administering it through an injection needle (not shown). Upon pressing down the advancing sleeve 5 by means of the lid 7, the teeth of the toothing 17 also glide over the catch 11 of the mechanism holder 3, wherein the catch 11 is out of mesh by means of the selected arrow-shape of the teeth of the toothing 17. The advance motion of the advancing sleeve 5 in the downward direction lasts until the cam 8 comes to a stop against the shoulder 18 of the mechanism holder 3 so that the selected dose of the liquid substance is administered. The injection device is prepared by renewed loading for one or more subsequent injections. The shaft 4 remains during the loading processes in the immediately before-given state by means of the toothing of catch 11 with the teeth of toothing 17. In particular, the shaft moves only in one direction, that is so to say downward, while the advancing sleeve lets itself move in two directions, so to say upward for loading and downward for applying. The injection device according to the invention can serve for the administering of medicine. However, it is also possible to administer lotions and other liquid substances with it.
  • The length of the injection lift X is determined by the individual differences of the steps of the stepped [0020] member 13 such that with an ampoule 2 with a specific diameter X is an integral multitude of a dose unit.

Claims (10)

1. Injection device for injecting a selectable dose of a liquid substance from an ampoule (2), located in an ampoule holder (1), comprising a piston (12) and a sleeve-shaped mechanism holder (3), mechanically coupled thereto, in the interior of which a longitudinally shiftable shaft (4) is provided which acts on the ampoule (2), the shaft (4) being surrounded by an also longitudinally shiftable advancing sleeve (5), mechanically coupled thereto, which in its upper end area is closed by a lid (7), characterized in that, for selecting a dose of the liquid substance to be injected, a dosing sleeve (6) with a stepped member (13) is provided which is disposed on the mechanism holder (3), in its upper end area, whereby the dose to be respectively administered is adjustable by a rotation of the dosing sleeve (6) with the stepped member (13).
2. Injection device according to
claim 1
, characterized in that the dosing sleeve (6) with the stepped member (13) surrounds the advancing sleeve (5).
3. Injection device according to
claim 1
 or
2
, characterized in that a cam (8), arranged on the advancing sleeve (5), comes to a stop upon pulling out the advancing sleeve (5) in the direction of the lid (7) against the step of the stepped member (13), respectively adjusted, and upon pressing down the advancing sleeve (5), the cam (8) comes to a stop against a shoulder (18) of the mechanism holder (3), resulting in the injection lift X.
4. Injection device according to one of the
claims 1
 to
3
, characterized in that, for the mechanical coupling of the shaft (4) with the advancing sleeve (5), the shaft (4) is provided with a toothing (17) which cooperates with a locking cam (10) of the advancing sleeve (5).
5. Injection device according to one of the
claims 1
 to
4
, characterized in that the depth of tooth of the toothings (17) on the shaft (4) corresponds to a step height of the stepped member (13).
6. Injection device according to one of the
claims 1
 to
5
, characterized in that, in the area of its lower end, the mechanism holder (3) comprises a catch (11) which cooperates with the toothing (17) of the shaft (4).
7. Injection device according to one of the
claims 1
 to
6
, characterized in that the dosing sleeve (6) is composed of an operating element (16) having a profile, a cylinder (15) with dose imprint adjoining thereto, a catch stop (14), and the stepped member (13) adjoining thereto.
8. Injection device according to one of the
claims 1
 to
7
, characterized in that the dose imprint on the cylinder (15) is visible via a window (9) in the mechanism holder (3).
9. Injection device according to one of the
claims 1
 to
8
, characterized in that, in its interior, the mechanism holder (3) comprises a multitude of bulges (19) into which the projections (20) of the stepped member (13) catch.
10. Injection device according to one of the
claims 1
 to
9
, characterized for the administering of medicines.
US09/888,669 1996-04-02 2001-06-25 Injection device Expired - Lifetime US6383167B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US09/888,669 US6383167B2 (en) 1996-04-02 2001-06-25 Injection device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
WOPCT/CH96/00115 1996-04-02
PCT/CH1996/000115 WO1997036625A1 (en) 1996-04-02 1996-04-02 Injection device
US08/983,553 US6277101B1 (en) 1996-04-02 1996-04-02 Injection device
US09/888,669 US6383167B2 (en) 1996-04-02 2001-06-25 Injection device

Related Parent Applications (1)

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US08/983,553 Continuation US6277101B1 (en) 1996-04-02 1996-04-02 Injection device

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US20010034507A1 true US20010034507A1 (en) 2001-10-25
US6383167B2 US6383167B2 (en) 2002-05-07

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US08/983,553 Expired - Lifetime US6277101B1 (en) 1996-04-02 1996-04-02 Injection device
US09/888,669 Expired - Lifetime US6383167B2 (en) 1996-04-02 2001-06-25 Injection device

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US08/983,553 Expired - Lifetime US6277101B1 (en) 1996-04-02 1996-04-02 Injection device

Country Status (9)

Country Link
US (2) US6277101B1 (en)
EP (1) EP0831947B1 (en)
JP (1) JP3483575B2 (en)
AT (1) ATE224216T1 (en)
DE (1) DE59609696D1 (en)
DK (1) DK0831947T3 (en)
ES (1) ES2183939T3 (en)
PT (1) PT831947E (en)
WO (1) WO1997036625A1 (en)

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Publication number Priority date Publication date Assignee Title
US20130123686A1 (en) * 2008-12-05 2013-05-16 Ams Research Corporation Needleless injection device components, systems, and methods
WO2013153011A1 (en) 2012-04-11 2013-10-17 Sanofi-Aventis Deutschland Gmbh Cartridge holder and pen-type injector
US9526844B2 (en) 2003-03-03 2016-12-27 Sanofi-Aventis Deutschland Gmbh Pen-type injector
US11033685B2 (en) * 2015-10-22 2021-06-15 Haselmeier Ag Injection device

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