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Patentes

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Número de publicaciónUS20020119711 A1
Tipo de publicaciónSolicitud
Número de solicitudUS 10/038,487
Fecha de publicación29 Ago 2002
Fecha de presentación4 Ene 2002
Fecha de prioridad9 Jun 1997
También publicado comoCA2291105A1, CA2291105C, DE69837006D1, DE69837006T2, EP0987982A1, EP0987982A4, EP0987982B1, US5954643, US6368141, US7402153, US7660615, US20040193025, US20080064944, WO1998056293A1
Número de publicación038487, 10038487, US 2002/0119711 A1, US 2002/119711 A1, US 20020119711 A1, US 20020119711A1, US 2002119711 A1, US 2002119711A1, US-A1-20020119711, US-A1-2002119711, US2002/0119711A1, US2002/119711A1, US20020119711 A1, US20020119711A1, US2002119711 A1, US2002119711A1
InventoresNannette VanAntwerp, Edgardo Halili
Cesionario originalMinimed, Inc.
Exportar citaBiBTeX, EndNote, RefMan
Enlaces externos: USPTO, Cesión de USPTO, Espacenet
Insertion set for a transcutaneous sensor
US 20020119711 A1
Resumen
An improved insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a mounting base defining an upwardly open channel for receiving and supporting a flexible thin film sensor, in combination with a cap assembled with said mounting base to capture and retain a proximal end of the sensor within said channel. The sensor further includes a distal segment with sensor electrodes thereon which protrudes from the mounting base for transcutaneous placement, wherein the sensor distal segment is slidably carried by a slotted insertion needle fitted through the assembled base and cap. Placement of the insertion set against the patient's skin causes the insertion needle to pierce the skin to carry the sensor electrodes to the desired subcutaneous site, after which the insertion needle can be slidably withdrawn from the insertion set. The mounting base further includes a fitting and related snap latch members for mated slide-fit releasable coupling of conductive contact pads on a proximal end of the sensor to a cable connector for transmitting sensor signals to a suitable monitoring device.
Imágenes(8)
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Reclamaciones(35)
What is claimed is:
1. A transcutaneous sensor insertion set, comprising:
a mounting base adapted for mounting onto a patient's skin, said mounting base having an upwardly open channel formed therein;
a flexible sensor having a proximal segment seated within said channel and a distal segment protruding from said mounting base with at least one sensor electrode thereon;
a retainer cap mounted on said mounting base to close said channel for retaining said sensor proximal segment within said channel; and
an insertion needle extending through said retainer cap and mounting base, said insertion needle defining means engageable with at least a portion of said sensor distal segment for transcutaneously placing said sensor distal segment and for subcutaneously placing said at least one electrode when said mounting base is placed against a patient's skin, said insertion needle being withdrawable from said sensor and said mounting base and retainer cap.
2. The transcutaneous sensor insertion set of claim 1 wherein said means for transcutaneously placing said sensor distal segment comprises a longitudinally extending slot formed along one side of said insert needle, said sensor distal segment and a portion of said sensor proximal segment being slidably carried by said insertion needle, and said insertion needle being slidably withdrawable therefrom.
3. The transcutaneous sensor insertion set of claim 1 wherein said retainer cap includes means for snap fit mounting onto said mounting base.
4. The transcutaneous sensor insertion set of claim 1 wherein said retainer cap and said mounting base are constructed from molded plastic.
5. The transcutaneous sensor insertion set of claim 1 wherein said retainer cap includes means for frictionally capturing said sensor proximal segment within said channel.
6. The transcutaneous sensor insertion set of claim 1 wherein said channel is formed on said mounting base to extend angularly forwardly and downwardly from a front end of said mounting base, whereby said sensor distal segment protrudes forwardly and downwardly from said mounting base.
7. The transcutaneous sensor insertion set of claim 1 further including a protective cannula having said sensor distal segment and at least a portion of said sensor proximal segment received therein, said retainer cap engaging said cannula to retain said sensor proximal segment within said channel.
8. The transcutaneous sensor insertion set of claim 7 wherein said retainer cap includes means for snap fit mounting onto said mounting base.
9. The transcutaneous sensor insertion set of claim 7 wherein said retainer cap includes teeth means for engaging and retaining said cannula.
10. The transcutaneous sensor insertion set of claim 7 wherein said cannula includes means for slide-fit engagement with said insertion needle.
11. The transcutaneous sensor insertion of claim 7 wherein said cannula has at least one window formed therein in general alignment with said at least one sensor electrode to expose said sensor electrode through said window when said sensor is slidably received within said cannula.
12. The transcutaneous sensor insertion set of claim 1 wherein said sensor further includes a head formed generally at a proximal end thereof and including at least one conductive contact pad, said mounting base including a cable fitting adapted for releasable coupling to a cable connector, said cable fitting defining a seat for supporting and retaining said sensor head.
13. The transcutaneous sensor insertion set of claim 1 wherein said mounting base further includes snap fit latch means for releasable coupling to a cable connector.
14. The transcutaneous sensor insertion set of claim 1 further including a cable connector, said mounting base and said cable connector having releasably interengageable snap fit latch members.
15. The transcutaneous sensor insertion set of claim 1 further including an enlarged hub mounted at a rear end of said insertion needle, said hub and said mounting base including cooperatively interfitting alignment surfaces for guiding said insertion needle into assembly and withdrawal from said sensor.
16. The transcutaneous sensor insertion set of claim 15 wherein said cooperatively interfitting alignment surfaces further limit rotation of said insertion needle relative to said mounting base.
17. The transcutaneous sensor insertion set of claim 15 wherein said hub comprises an enlarged rear wing for facilitated manual grasping, and a bifurcated nose defining said cooperatively interfitting alignment surfaces in combination with said mounting base.
18. The transcutaneous sensor insertion set of claim 17 wherein said retainer cap includes a raised segment sized to fit within said bifurcated nose of said hub.
19. The transcutaneous sensor insertion set of claim 1 wherein said sensor comprises a thin film sensor.
20. The transcutaneous sensor insertion set of claim 1 further including means for removable attachment of said mounting base to a patient's skin.
21. The transcutaneous sensor insertion set of claim 1 wherein said retainer cap has a needle port formed therein for sliding reception of said insertion needle.
22. A transcutaneous sensor insertion set, comprising:
a mounting base adapted for mounting onto a patient's skin, said mounting base having an upwardly open channel formed therein, and further including a cable fitting generally at a rear end of said channel and adapted for releasable coupling with a cable connector, said channel extending from said cable fitting to a front end of said mounting base;
a flexible sensor having a head formed generally at a proximal end thereof, a proximal segment extending from said head and a distal segment having at least one sensor electrode thereon, said head including at least one contact pad conductively coupled to said electrode;
a protective cannula having said sensor distal segment and at a portion of said sensor proximal segment received therein;
said sensor proximal segment and a portion of said cannula being seated within said channel formed in said mounting base, with said sensor distal segment and the remainder of said cannula protruding from said mounting base;
a retainer cap mounted on said mounting base to close said channel and to engage the cannula portion therein to capture and retain said cannula portion and said sensor proximal segment within said channel; and
an insertion needle extending through the assembled retainer cap and mounting base, said cannula including means for engagement with said needle upon insertion of said needle through the assemble retainer cap and mounting base, said insertion needle being slidably withdrawable from said cannula and from said retainer cap and mounting base.
23. The transcutaneous sensor insertion set of claim 22 wherein said insertion needle defines a longitudinally extending slot for slide-fit engagement with and for sliding withdrawal from said cannula.
24. The transcutaneous sensor insertion set of claim 22 wherein said retainer cap includes means for snap fit mounting onto said mounting base.
25. The transcutaneous sensor insertion set of claim 22 wherein said retainer cap and said mounting base are constructed from molded plastic.
26. The transcutaneous sensor insertion set of claim 22 wherein said retainer cap includes teeth means for engaging and retaining said cannula.
27. The transcutaneous sensor insertion set of claim 22 wherein said channel is formed on said mounting base to extend angularly forwardly and downwardly from a front end of said mounting base, whereby said sensor distal segment protrudes forwardly and downwardly from said mounting base.
28. The transcutaneous sensor insertion set of claim 22 wherein said cable fitting includes a recessed seat for supporting and retaining said sensor head.
29. The transcutaneous sensor insertion set of claim 22 wherein said mounting base further includes snap fit latch means for releasable coupling to a cable connector.
30. The transcutaneous sensor insertion set of claim 22 further including a cable connector, said mounting base and said cable connector having releasably interengageable snap fit latch members.
31. The transcutaneous sensor insertion set of claim 22 further including an enlarged hub mounted at a rear end of said insertion needle, said hub and said mounting base including cooperatively interfitting alignment surfaces for guiding said insertion needle into assembly and withdrawal from said cannula.
32. The transcutaneous sensor insertion set of claim 31 wherein said cooperatively interfitting alignment surfaces further limit rotation of said insertion needle relative to said mounting base.
33. The transcutaneous sensor insertion set of claim 22 wherein said cable fitting comprises a tubular element having a central bore formed therein for pass through reception of a portion of said sensor proximal segment, said bore being generally coaxially aligned with said channel.
34. The transcutaneous sensor insertion set of claim 33 wherein said cable fitting includes a generally D-shaped key formed as a rearward extension of said tubular element, said key defining a recessed seat for receiving and supporting said sensor head.
35. The transcutaneous sensor insertion set of claim 34 wherein said recessed seat is formed at ramp angle relative to a central axis of said bore.
Descripción
    BACKGROUND OF THE INVENTION
  • [0001]
    This invention relates generally to devices and methods for placing a sensor at a selected site within the body of a patient. More particularly, this invention relates to an improved and relatively simple insertion set for quick and easy transcutaneous placement of a flexible thin film sensor of the type used, for example, to obtain blood glucose readings.
  • [0002]
    In recent years, a variety of electrochemical sensors have been developed for a range of applications, including medical applications for detecting and/or quantifying specific agents in a patient's blood and other body fluids. As one example, glucose sensors have been developed for use in obtaining an indication of blood glucose levels in a diabetic patient. Such readings can be especially useful in monitoring and/or adjusting a treatment regimen which typically includes regular administration of insulin to the patient. In this regard, blood glucose readings are particularly useful in conjunction with semi-automated medication infusion pumps of the external type, as generally described in U.S. Pat. Nos. 4,562,751; 4,678,408; and 4,685,903; or automated implantable medication infusion pumps, as generally described in U.S. Pat. No. 4,573,994.
  • [0003]
    Relatively small and flexible electrochemical sensors have been developed for subcutaneous placement of sensor electrodes in direct contact with patient blood or other extracellular fluid, wherein such sensors can be used to obtain periodic readings over an extended period of time. In one form, flexible transcutaneous sensors are constructed in accordance with thin film mask techniques wherein an elongated sensor includes thin film conductive elements encased between flexible insulative layers of polyimide sheet or similar material. Such thin film sensors typically include exposed electrodes at a distal end for subcutaneous placement in direct contact with patient blood or the like, and exposed conductive contact pads at an externally located proximal end for convenient electrical connection with a suitable monitoring device. Such thin film sensors hold significant promise in patient monitoring applications, but unfortunately have been difficult to place transcutaneously with the sensor electrodes in direct contact with patient blood or other body fluid. Improved thin film sensors and related insertion sets are described in commonly assigned U.S. Pat. Nos. 5,390,671; 5,391,250; 5,482,473; 5,299,571; 5,586,553 and 5,568,806, which are incorporated by reference herein.
  • [0004]
    Notwithstanding the foregoing improvements in and to thin film electrochemical sensors and related transcutaneous insertion sets, there exists an on-going need for further improvements in such insertion sets particularly with respect to facilitated and cost efficient manufacture, improvements in quick and easy transcutaneous placement of the thin film sensor, and simplified attachment of the sensor to a conductive cable or the like for coupling of sensor signals to the associated monitoring device. The present invention fulfills these needs and provides further related advantages.
  • SUMMARY OF THE INVENTION
  • [0005]
    In accordance with the invention, an improved insertion set is provided for transcutaneously placing a flexible sensor such as a thin film electrochemical sensor at a selected site within the body of a patient. The insertion set comprises a mounting base adapted for seated mounting onto the patient's skin, in combination with a cap for assembly therewith to cooperatively capture and retain the sensor. A distal segment of the sensor with sensor electrodes thereon is slidably carried by a slotted hollow insertion needle fitted through the assembled mounting base and cap for piercing the patient's skin to subcutaneously place the sensor electrodes as the mounting base is pressed onto the patient's skin. The insertion needle can then be slidably withdrawn to leave the sensor electrodes at the desired subcutaneous site. A proximal end of the sensor including conductive contact pads is carried by a cable fitting on the mounting base for slide-fit coupling with a cable connector, with the mounting base and cable connector including snap fit latch members for releasable interconnection.
  • [0006]
    In the preferred form, the sensor comprises an elongated thin film element with a head at a proximal end thereof including the contact pads seated in a predetermined position and orientation in the cable fitting formed on the mounting base. A proximal segment of the sensor extends from the cable fitting within a recessed channel defined in an upper surface of the mounting base, with the sensor distal segment protruding angularly forwardly and downwardly from the mounting base. The cap is designed for assembly with the mounting base, as by snap fit interconnection therewith, to capture and retain the proximal sensor segment within the recessed channel. In the preferred form, the sensor distal segment and at least a portion of the proximal segment is protectively carried within a cannula. A proximal portion of the cannula is seated within the channel, and a distal cannular portion extends from the mounting base and is slidably carried by the slotted insertion needle as described in U.S. Pat. No. 5,586,553. The insertion needle is slidably fitted through the assembled mounting base and cap, and is connected at its upper end to an enlarged hub for facilitated manipulation thereof. The hub includes keyed alignment surfaces which cooperate with associated alignment or guide surfaces on the assembled base and cap to prevent or minimize needle rotation relative to the sensor and to guide the needle during slide-fit engagement and disengagement therewith.
  • [0007]
    The cable fitting formed on the mounting base is sized and shaped for slide-fit coupling with a matingly shaped fitting formed on the cable connector, for electrically coupling the sensor contact pads with individual associated conductors of an electrical cable. In the preferred form, the mounting base includes at least one and preferably a plurality of latch arms for snap fit engagement with latch recesses formed on the cable connector to couple the mounting base and cable connector together with their respective fittings properly engaged.
  • [0008]
    In use, the snap fit latch members permit quick and easy connection of the insertion set mounting base to the cable connector. The insertion set can then be pressed against the patient's skin so that the insertion needle pierces the skin and carries the cannula with sensor distal segment therein to the desired subcutaneous position. The mounting base is then affixed to the skin, as by suitable adhesive means, and the insertion needle is withdrawn from the patient leaving the cannula and the sensor therein at the selected insertion site. When it is necessary or appropriate to replace with sensor, the used insertion set can be simply removed from the patient to withdraw the sensor from the patient's skin, followed by detachment of the insertion set from the cable connector for disposal thereof. A replacement insertion set is then coupled to the cable connector and transcutaneously placed on the patient as described above.
  • [0009]
    Other features and advantages of the invention will become more apparent from the following detailed description, taken in conjunction with the accompanying drawings which illustrate, by way of example, the principles of the invention.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0010]
    The accompanying drawings illustrate the invention. In such drawings:
  • [0011]
    [0011]FIG. 1 is a fragmented perspective view illustrating a sensor insertion set embodying the novel features of the invention, wherein the insertion set is depicted in assembled relation with a cable connector;
  • [0012]
    [0012]FIG. 2 is an exploded perspective view of the insertion set;
  • [0013]
    [0013]FIG. 3 is an enlarged and exploded perspective view showing assembly of the insertion set components, and depicting an upper side of an insertion set mounting base;
  • [0014]
    [0014]FIG. 4 is an exploded perspective view showing assembly of the insertion set components, depicting an underside of the mounting base;
  • [0015]
    [0015]FIG. 5 is an underside perspective view of the mounting base shown in FIG. 4, showing a proximal end or head of a flexible thin film sensor seated on the mounting base;
  • [0016]
    [0016]FIG. 6 is another exploded perspective view illustrating assembly of a retainer cap on an upper side of the mounting base;
  • [0017]
    [0017]FIG. 7 is an exploded perspective view similar to FIG. 6, and depicting further assembly of the retainer cap with the mounting base;
  • [0018]
    [0018]FIG. 8 is an enlarged perspective view showing the underside of the retainer cap of FIGS. 6 and 7;
  • [0019]
    [0019]FIG. 9 is a perspective view similar to FIGS. 6 and 7, and showing the retainer cap in assembled relation with the mounting base;
  • [0020]
    [0020]FIG. 10 is a perspective view similar to FIG. 9, and depicting an insertion needle installed on the assembled mounting base and retainer cap;
  • [0021]
    [0021]FIG. 11 is an enlarged sectional view taken generally on the line 11-11 of FIG. 10;
  • [0022]
    [0022]FIG. 12 is a front end perspective view of the cable connector of FIGS. 1 and 2;
  • [0023]
    [0023]FIG. 13 is an exploded perspective view illustrating assembly of the cable connector with the insertion set;
  • [0024]
    [0024]FIG. 14 is a perspective view showing sliding removal of the insertion needle from the insertion set, following placement of the mounting base onto the skin of a patient; and
  • [0025]
    [0025]FIG. 15 is a perspective view showing the insertion set and cable connector mounted onto the skin of a patient, following removal of the insertion needle.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT
  • [0026]
    As shown in the exemplary drawings, an improved insertion set referred to generally in FIGS. 1 and 2 by the reference numeral 10 is provided for placing a biological sensor 12 (FIG. 2) in a selected transcutaneous position on a patient. The insertion set 10 includes an insertion needle 14 for placing a distal end segment of the sensor 12 having sensor electrodes 15 thereon (FIG. 3) in a selected subcutaneous position in direct contact with patient blood or other body fluid. The insertion set further supports the sensor 12 for quick and easy coupling of a proximal end or head 16 having conductive contact pads 18 thereon (FIG. 3) with a cable connector 20 (FIG. 1) for coupling sensor signals in turn via an electrical cable 22 to a suitable monitoring device (not shown).
  • [0027]
    The insertion set 10 of the present invention is particularly designed for facilitating quick and easy transcutaneous placement of a flexible thin film electrochemical sensor of the type used for monitoring specific blood parameters representative of patient condition. The insertion set 10 is designed to place the sensor 12 subcutaneously or at another selected site within the body of a patient, in a manner minimizing patient discomfort and trauma. In one preferred application, the sensor 12 may be designed to monitor blood glucose levels, and may be used in conjunction with automated or semi-automated medication infusion pumps of the external or implantable type as described in U.S. Pat. Nos. 4,562,751; 4,678,408; 4,685,903; and 4,573,994, to deliver insulin to a diabetic patient. However, it will be understood that the sensor may be designed to monitor other patient body fluid parameters for other applications. Further, is will be understood that the term “patient” can be broadly construed to encompass humans and other animals, and that the term “blood” encompasses patient blood and other extracellular patient fluids.
  • [0028]
    As shown best in FIGS. 2-4, the flexible thin film sensor 12 comprises a relatively thin and elongated element which can be constructed according to so-called thin film mask techniques to include elongated conductive elements 24 (FIG. 3) embedded or encased between layers of a selected insulative sheet material such as polyimide film or sheet. The proximal end or head 16 of the sensor 12 is relatively enlarged and defines the conductive contact pads 18 which are exposed through the insulative sheet material for electrical connection to the cable 22, as will be described in more detail. An opposite or distal end segment of the sensor 12 includes the corresponding plurality of exposed sensor electrodes 15 for contacting patient body fluid when the sensor distal segment is placed into the body of the patient. The sensor electrodes 15 generate electrical signals representative of patient condition, wherein these signals are transmitted via the contact pads 18 and the cable 22 to an appropriate monitoring device (not shown) for recordation and/or display to monitor patient condition. Further description of flexible thin film sensors of this general type may be found in U.S. Pat. No. 5,391,250, which is incorporated by reference herein.
  • [0029]
    The sensor 12 is carried by the insertion set 10 which is adapted for placement onto the skin of a patient (FIGS. 14-15) at the selected insertion site. As shown in FIGS. 1-7, the insertion set 10 generally comprises a compact mounting base 30 having a generally planar or flat underside surface 32 (FIGS. 4-5) attached to an adhesive patch 34 for press-on adhesive mounting onto the patient's skin. The mounting base 30 is conveniently and economically constructed as a unitary molding of lightweight plastic to include a rear cable fitting 36 for slide-fit coupling with the cable connector 20. The rear cable fitting 36 cooperates with an upwardly open recessed groove or channel 38 formed in an upper surface 40 of the mounting base 30 (FIGS. 2, 3, 6 and 7) to receive and support the sensor 12.
  • [0030]
    More particularly, FIGS. 2-5 show the rear cable fitting 36 of the mounting base 30 to comprise a rearwardly projecting tubular element 42 defining a central bore 44 aligned generally coaxially with a rearward end of the recessed channel 38. The tubular element 42 includes external grooves 46 (FIG. 2) for receiving seal rings 48 adapted for sealed slide-fit engagement with the cable connector 20, as will be described. Importantly, the rearward end of the tubular element 42 terminates in a generally D-shaped or half-circle fitting key 50 formed as a rearward extension thereof, and which incorporates a shallow recessed flat or seat 52 formed at the rearward end of the bore 44. This recessed seat 52 is sized and shaped to receive and support the proximal head 16 of the sensor 12, with a proximal end of the elongated sensor 12 extending from said head 16 through the bore 44 and lying within the recessed channel 38. In the preferred form, the head 16 of the sensor 12 is secured and seated (FIG. 5) within the recessed seat 52 by means of a suitable adhesive or the like. In addition, subsequent to placement of the sensor 12 through the bore 44, in the preferred form, the bore 44 is hermetically sealed with a suitable sealant such as curable silicone sealer or the like. For facilitated slide-fit engagement with the cable connector 20, the seat 52 is formed to ramp angularly rearwardly and upwardly from a central axis of the bore 44, thereby supporting the sensor head 16 with the contact pads 18 presented downwardly and angularly rearwardly.
  • [0031]
    The recessed channel 38 in the mounting base 30 thus receives and supports the proximal segment of the thin film sensor 12. As shown in FIGS. 3, 6 and 7, the recessed channel 38 extends forwardly from the fitting bore 44 with a generally horizontal orientation, and then turns downwardly and forwardly at an angle of about 45 degrees to extend along an angled face 53 within a forwardly open gap 54 formed in the front end or nose of the mounting base. A cannula 58 is slidably fitted over at least a portion of the proximal segment of the sensor 12, to extend also over the distal segment to encase and protect the sensor. In the preferred form, the cannula is constructed from a lightweight plastic material such as a urethane based plastic, and has a double lumen configuration as shown in FIG. 11 with the sensor slidably received within one lumen thereof. The double lumen cannula 58 is especially suited for slide-fit engagement with and disengagement from the insertion needle 14, as will be described in more detail, and includes a window 59 (FIG. 4) to expose the sensor electrodes 15. The specific cannula construction for receiving and supporting the sensor 12, and for slidably interfitting with the insertion needle 14, is shown and described in more detail in U.S. Pat. No. 5,586,553, which is incorporated by reference herein.
  • [0032]
    The proximal end of the sensor 12 and the portion of the cannula 58 thereon are folded as shown in FIG. 7 to follow the contour of the mounting base channel 38, so that the distal segment of the sensor and the cannula thereon extend and protrude downwardly and forwardly from the front of the mounting base 30. The sensor and cannula are captured and retained in this orientation by a retainer cap 60 shown in FIGS. 7-9. This retainer cap 60 is also formed conveniently and economically as a lightweight plastic molding and includes means for quick and easy snap fit installation onto the mounting base 30. More specifically, the cap 60 has an elongated and relatively narrow geometry to include a rear head 62 with a pair of upright keys 64 formed on opposite sides thereof for vertical slide-fit reception into a mating pair of keyways 66 formed in upright support brackets 68 on the mounting base 30. A front or nose end 70 of the retainer cap 60 is sized and shaped to fit matingly into the angularly formed gap 54 in the mounting base 30 to retain the cannula 58 and sensor 12 seated in the channel 38 of the ramped face 53. This cap nose 70 includes snap tabs 72 on opposite sides thereof for snap-fit engagement with snap detents 74 lining the gap 54. When the retainer cap 60 is assembled with the mounting base 30, these components cooperatively close the top of the channel 38 to capture and retain the sensor and cannula therein. In this regard, the underside of the cap 60 desirably includes retainer means such as a plurality of retainer teeth 76 (FIG. 8) for frictionally gripping and retaining the cannula with an interference fit within the channel 38. Alternative means can be used to secure the cap 60 to the mounting base 30, such as an adhesive attachment, or ultrasonic bonding means or the like.
  • [0033]
    The retainer cap 60 further defines a needle port 78 (FIGS. 9 and 10) for pass through reception of the insertion needle 14. The insertion needle 14 has a hollow and longitudinally slotted configuration (FIG. 11) with a pointed or sharpened tip and a rear end anchored to an enlarged hub 80. The hub 80 is manually manipulated to fit the needle 14 through the cap port 78, in order to slide the slotted needle into engagement with the cannula 58 within the forwardly and downwardly angled portion of the channel 38. In this regard, the needle port 78 is sized and shaped to orient the insertion needle 14 for proper angular and rotational alignment with the cannula 58 to insure correct slide-fit engagement therebetween.
  • [0034]
    More particularly, the hub 80 includes an enlarged tab-like wing 82 adapted for easy grasping and handling between the thumb and index finger. This enlarged wing 82 projects upwardly from a bifurcated nose 84 which is sized and shaped to seat onto the mounting base upper surface 40, on opposite sides of a raised central section 86 of the retainer cap 60. The hub nose 84 is contoured to defined keyed alignment or guide surfaces 88 for matingly contacting associated keyed alignment surfaces on the mounting base 30, defined by the upper surface 40 and an angularly presented forward face 90 of the support brackets 68. With this geometry, the hub 80 is slidably displaced against the mounting base with the insertion needle 14 extending into and through the cap port 78 at the correct angular and rotational orientation for slide-fit engagement with and disengagement from the cannula 58. In the preferred form, the insertion needle 14 slidably assembles with the cannula 58 as described in U.S. Pat. No. 5,586,553 to provide a generally circular cross sectional profile (FIG. 11) protruding from the mounting base.
  • [0035]
    [0035]FIGS. 12 and 13 show the cable connector 20 for coupling with the assembled insertion set 10. As shown, the cable connector 20 comprises a compact coupling element which can also be constructed from lightweight molded plastic. The cable connector 20 defines a socket fitting 92 for mating slide-fit engagement with the rear cable fitting 36 of the mounting base 30. This socket fitting 92 has a cylindrical entry portion 93 which merges with a generally D-shaped or half-circle step portion 94 sized to receive the D-shaped key 50 of the fitting 36. As shown, the socket fitting 92 includes a plurality of conductive contacts 96 (FIG. 12) positioned on the step portion 94 for electrically coupled engagement with the contact pads 18 on the sensor 12, when the insertion set 10 and cable connector 20 are coupled together as viewed in FIG. 13. When assembled, the seal rings 48 sealingly engage the entry portion 93 of the socket fitting 92 to provide a sealed connection between the components. Importantly, the D-shaped geometry of the interfitting components 50 and 94 insure one-way interconnection for correct conductive coupling of the cable 22 to the sensor 12.
  • [0036]
    The insertion set 10 and the cable connector 20 are retained in releasably coupled relation by interengaging snap fit latch members. As shown, the mounting base 30 is formed to include a pair of rearwardly projecting cantilevered latch arms 97 which terminate at the rearward ends thereof in respective undercut latch tips 98. The latch arms 97 are sufficiently and naturally resilient for movement relative to the remainder of the mounting base 30, to permit the latch arms to be squeezed inwardly toward each other. The permissible range of motion accommodates snap fit engagement of the latch tips 98 into a corresponding pair of latch recesses 100 formed in the cable connector 20 on opposite sides of the socket fitting 92, wherein the latch recesses 100 are lined with latch keepers 102 for engaging said latch tips 98. The components can be disengaged for uncoupling when desired by manually squeezing the latch arms 97 inwardly toward each other for release from the latch keepers 102, while axially separating the mounting base 30 from the cable connector 20.
  • [0037]
    The insertion set 10 of the present invention is mounted on the patient's skin quickly and easily to transcutaneously place the sensor 12, as viewed in FIGS. 13-15. The insertion set 10 is initially coupled to the cable connector 20 by engaging the snap fit latch members, with the fitting components 36 and 92 engaged to electrically couple the sensor 12 to the cable 22. The insertion set 10 is then pressed against the patient's skin, typically after removing a protective needle guard (not shown) and a release film (also not shown) from the underside of the adhesive patch 34 to expose a pressure sensitive adhesive thereon. Pressing the set 10 against the skin causes the insertion needle 14 to pierce the skin and thereby carry the cannula 58 with the sensor electrodes 15 thereon to the desired subcutaneous position. The insertion needle 14 is then slidably disengaged from the cannula and sensor by withdrawing the needle from the patient. The insertion set 10 can be affixed more securely to the patient, if desired, by an overdressing (not shown).
  • [0038]
    When it is necessary or desirable to remove the sensor from the patient, the insertion set is simply removed from the patient's skin to withdraw the sensor from the subcutaneous site. The insertion set 10 is quickly and easily disassembled from the cable connector 20 by appropriate release of the snap fit latch members. A new insertion set 10 can then assembled with the cable connector and quickly placed on the patient to subcutaneously position a new sensor.
  • [0039]
    A variety of modifications and improvements in and to the transcutaneous insertion set of the present invention will be apparent to those persons skilled in the art. Accordingly, no limitation on the invention is intended by way of the foregoing description and accompanying drawings, except as set forth in the appended claims.
Citas de patentes
Patente citada Fecha de presentación Fecha de publicación Solicitante Título
US3921631 *1 Ago 197425 Nov 1975Vicra Sterile IncCatheter insertion device and method of catheter introduction
US4235234 *30 Nov 197825 Nov 1980Martin John K IiiSubcutaneous injection system
US4562751 *6 Ene 19847 Ene 1986Nason Clyde KSolenoid drive apparatus for an external infusion pump
US4573994 *7 Dic 19814 Mar 1986The Johns Hopkins UniversityRefillable medication infusion apparatus
US4678408 *24 Sep 19857 Jul 1987Pacesetter Infusion, Ltd.Solenoid drive apparatus for an external infusion pump
US4682981 *5 Ago 198528 Jul 1987Terumo Kabushiki KaishaMedical device
US4685903 *6 Ene 198411 Ago 1987Pacesetter Infusion, Ltd.External infusion pump apparatus
US4840613 *27 Abr 198820 Jun 1989Menlo Care, Inc.Protective sheath for catheter assembly
US5249576 *24 Oct 19915 Oct 1993Boc Health Care, Inc.Universal pulse oximeter probe
US5390671 *15 Mar 199421 Feb 1995Minimed Inc.Transcutaneous sensor insertion set
US5522803 *8 Mar 19944 Jun 1996Pharma Plast International A/SInfusion set for an intermittent or continuous administration of a therapeutical substance
US5545143 *7 Ene 199413 Ago 1996T. S. I. MedicalDevice for subcutaneous medication delivery
US6224571 *14 Nov 19971 May 2001Venetec International, Inc.Medical line securement device
US6302866 *13 May 199916 Oct 2001Disetronic Licensing AgCatheter head for subcutaneous administration of an substance
US6450973 *16 Jun 200017 Sep 2002Kieran P. J. MurphyBiopsy gun
US6488663 *7 Jun 20013 Dic 2002Arta Plast AbInfusion apparatus for administering a medicine
US6749589 *29 Sep 200015 Jun 2004Sterling Medications, Inc.Subcutaneous injection set for use with a reservoir that has a septum
Citada por
Patente citante Fecha de presentación Fecha de publicación Solicitante Título
US705248318 Dic 200130 May 2006Animas CorporationTranscutaneous inserter for low-profile infusion sets
US731881614 Mar 200315 Ene 2008Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US732923920 Feb 200312 Feb 2008Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US74944813 Dic 200424 Feb 2009Medtronic Minimed, Inc.Multi-position infusion set device and process
US752086710 Nov 200321 Abr 2009Medtronic Minimed, Inc.Subcutaneous infusion set
US765495610 Mar 20052 Feb 2010Dexcom, Inc.Transcutaneous analyte sensor
US767940727 Abr 200416 Mar 2010Abbott Diabetes Care Inc.Method and apparatus for providing peak detection circuitry for data communication systems
US769796728 Sep 200613 Abr 2010Abbott Diabetes Care Inc.Method and apparatus for providing analyte sensor insertion
US771357410 Mar 200511 May 2010Dexcom, Inc.Transcutaneous analyte sensor
US77158933 Dic 200411 May 2010Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US775656130 Sep 200513 Jul 2010Abbott Diabetes Care Inc.Method and apparatus for providing rechargeable power in data monitoring and management systems
US776113027 Mar 200720 Jul 2010Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US77668294 Nov 20053 Ago 2010Abbott Diabetes Care Inc.Method and system for providing basal profile modification in analyte monitoring and management systems
US776840817 May 20063 Ago 2010Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US77713521 May 200810 Ago 2010Dexcom, Inc.Low oxygen in vivo analyte sensor
US777414518 Ene 200610 Ago 2010Dexcom, Inc.Transcutaneous analyte sensor
US77786801 Ago 200317 Ago 2010Dexcom, Inc.System and methods for processing analyte sensor data
US778333310 Mar 200524 Ago 2010Dexcom, Inc.Transcutaneous medical device with variable stiffness
US779702814 Abr 200814 Sep 2010Dexcom, Inc.System and methods for processing analyte sensor data
US781123126 Dic 200312 Oct 2010Abbott Diabetes Care Inc.Continuous glucose monitoring system and methods of use
US782698118 Ene 20052 Nov 2010Dexcom, Inc.System and methods for processing analyte sensor data
US783128728 Abr 20089 Nov 2010Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US785776022 Feb 200628 Dic 2010Dexcom, Inc.Analyte sensor
US78605447 Mar 200728 Dic 2010Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US78698536 Ago 201011 Ene 2011Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US788346430 Sep 20058 Feb 2011Abbott Diabetes Care Inc.Integrated transmitter unit and sensor introducer mechanism and methods of use
US78847292 Ago 20108 Feb 2011Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US788569710 Mar 20058 Feb 2011Dexcom, Inc.Transcutaneous analyte sensor
US78856996 Ago 20108 Feb 2011Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US78968093 Nov 20081 Mar 2011Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US789951117 Ene 20061 Mar 2011Dexcom, Inc.Low oxygen in vivo analyte sensor
US79013541 May 20088 Mar 2011Dexcom, Inc.Low oxygen in vivo analyte sensor
US7905833 *21 Jun 200515 Mar 2011Dexcom, Inc.Transcutaneous analyte sensor
US79144503 May 201029 Mar 2011Dexcom, Inc.System and methods for processing analyte sensor data
US791718616 Nov 200929 Mar 2011Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US79209069 Mar 20065 Abr 2011Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US79209077 Jun 20075 Abr 2011Abbott Diabetes Care Inc.Analyte monitoring system and method
US792245829 Dic 200812 Abr 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US792532123 Mar 201012 Abr 2011Dexcom, Inc.System and methods for processing analyte sensor data
US792727429 Jul 200819 Abr 2011Dexcom, Inc.Integrated receiver for continuous analyte sensor
US79288508 May 200819 Abr 2011Abbott Diabetes Care Inc.Analyte monitoring system and methods
US793363923 Mar 201026 Abr 2011Dexcom, Inc.System and methods for processing analyte sensor data
US793505714 Ene 20093 May 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US794698410 Mar 200524 May 2011Dexcom, Inc.Transcutaneous analyte sensor
US794938111 Abr 200824 May 2011Dexcom, Inc.Transcutaneous analyte sensor
US795526123 Mar 20107 Jun 2011Dexcom, Inc.System and methods for processing analyte sensor data
US795956923 Mar 201014 Jun 2011Dexcom, Inc.System and methods for processing analyte sensor data
US79764926 Ago 200912 Jul 2011Dexcom, Inc.Integrated delivery device for continuous glucose sensor
US797677822 Jun 200512 Jul 2011Abbott Diabetes Care Inc.Blood glucose tracking apparatus
US797910426 May 201012 Jul 2011Dexcom, Inc.System and methods for processing analyte sensor data
US798698623 Mar 201026 Jul 2011Dexcom, Inc.System and methods for processing analyte sensor data
US799310813 Abr 20059 Ago 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US799310929 Dic 20089 Ago 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US799807114 Oct 200916 Ago 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US80009019 Ago 201016 Ago 2011Dexcom, Inc.Transcutaneous analyte sensor
US800552424 Mar 201023 Ago 2011Dexcom, Inc.Signal processing for continuous analyte sensor
US800552514 Oct 200923 Ago 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US801017422 Ago 200330 Ago 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US802924529 Dic 20084 Oct 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US802925029 Dic 20084 Oct 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US802945921 Dic 20094 Oct 2011Abbott Diabetes Care Inc.Method and system for providing integrated medication infusion and analyte monitoring system
US802946021 Dic 20094 Oct 2011Abbott Diabetes Care Inc.Method and system for providing integrated medication infusion and analyte monitoring system
US804781129 Dic 20081 Nov 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US804781229 Dic 20081 Nov 2011Abbott Diabetes Care Inc.Variable volume, shape memory actuated insulin dispensing pump
US805260120 Ago 20088 Nov 2011Dexcom, Inc.System and methods for processing analyte sensor data
US80601731 Ago 200315 Nov 2011Dexcom, Inc.System and methods for processing analyte sensor data
US806497729 Jul 200922 Nov 2011Dexcom, Inc.Silicone based membranes for use in implantable glucose sensors
US80666394 Jun 200429 Nov 2011Abbott Diabetes Care Inc.Glucose measuring device for use in personal area network
US807351914 Oct 20096 Dic 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US807352025 May 20106 Dic 2011Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US80893637 Feb 20113 Ene 2012Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US810345629 Ene 200924 Ene 2012Abbott Diabetes Care Inc.Method and device for early signal attenuation detection using blood glucose measurements
US811213826 Sep 20087 Feb 2012Abbott Diabetes Care Inc.Method and apparatus for providing rechargeable power in data monitoring and management systems
US811224029 Abr 20057 Feb 2012Abbott Diabetes Care Inc.Method and apparatus for providing leak detection in data monitoring and management systems
US81236861 Mar 200728 Feb 2012Abbott Diabetes Care Inc.Method and apparatus for providing rolling data in communication systems
US812856214 Oct 20096 Mar 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US813317822 Feb 200613 Mar 2012Dexcom, Inc.Analyte sensor
US814911729 Ago 20093 Abr 2012Abbott Diabetes Care Inc.Analyte monitoring system and methods
US815048814 Oct 20093 Abr 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US816066911 Abr 200717 Abr 2012Dexcom, Inc.Transcutaneous analyte sensor
US81606711 Sep 201017 Abr 2012Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US816282930 Mar 200924 Abr 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US816780125 Mar 20101 May 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US817080310 Mar 20051 May 2012Dexcom, Inc.Transcutaneous analyte sensor
US81756739 Nov 20098 May 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US817771621 Dic 200915 May 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US818718311 Oct 201029 May 2012Abbott Diabetes Care Inc.Continuous glucose monitoring system and methods of use
US81952659 Feb 20115 Jun 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US820629716 Dic 200926 Jun 2012Dexcom, Inc.System and methods for processing analyte sensor data
US821613923 Sep 200910 Jul 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US822441310 Oct 200817 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US822655518 Mar 200924 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US822655728 Dic 200924 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US822655827 Sep 201024 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US822689131 Mar 200624 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring devices and methods therefor
US822953426 Oct 200724 Jul 2012Dexcom, Inc.Transcutaneous analyte sensor
US822953520 Feb 200924 Jul 2012Dexcom, Inc.Systems and methods for blood glucose monitoring and alert delivery
US822953627 May 201024 Jul 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US82315311 Jun 200631 Jul 2012Dexcom, Inc.Analyte sensor
US823153230 Abr 200731 Jul 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US823395812 Oct 200931 Jul 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US82339591 Sep 200631 Jul 2012Dexcom, Inc.Systems and methods for processing analyte sensor data
US823589621 Dic 20097 Ago 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US823624212 Feb 20107 Ago 2012Abbott Diabetes Care Inc.Blood glucose tracking apparatus and methods
US82496841 Sep 201021 Ago 2012Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US825190615 Abr 200928 Ago 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US825503117 Mar 200928 Ago 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US825725916 Oct 20084 Sep 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US82603929 Jun 20084 Sep 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US826039313 Jun 20074 Sep 2012Dexcom, Inc.Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US826572512 Oct 200911 Sep 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US82657269 Nov 200911 Sep 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US826824328 Dic 200918 Sep 2012Abbott Diabetes Care Inc.Blood glucose tracking apparatus and methods
US827302213 Feb 200925 Sep 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US827543723 Mar 200725 Sep 2012Dexcom, Inc.Transcutaneous analyte sensor
US82754399 Nov 200925 Sep 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US828047523 Feb 20092 Oct 2012Dexcom, Inc.Transcutaneous analyte sensor
US82825498 Dic 20049 Oct 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US828255029 Jul 20089 Oct 2012Dexcom, Inc.Integrated receiver for continuous analyte sensor
US828535423 Mar 20109 Oct 2012Dexcom, Inc.System and methods for processing analyte sensor data
US82874537 Nov 200816 Oct 2012Dexcom, Inc.Analyte sensor
US828745427 Sep 201016 Oct 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US829055924 Oct 200816 Oct 2012Dexcom, Inc.Systems and methods for processing sensor data
US829056018 Nov 200816 Oct 2012Dexcom, Inc.Transcutaneous analyte sensor
US829056123 Sep 200916 Oct 2012Dexcom, Inc.Signal processing for continuous analyte sensor
US82905623 May 201016 Oct 2012Dexcom, Inc.System and methods for processing analyte sensor data
US829281027 Ene 201123 Oct 2012Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US82928499 Sep 201023 Oct 2012Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US83065989 Nov 20096 Nov 2012Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US831174926 May 201113 Nov 2012Dexcom, Inc.Transcutaneous analyte sensor
US83134341 Mar 200720 Nov 2012Dexcom, Inc.Analyte sensor inserter system
US831775927 Ene 200927 Nov 2012Medtronic Minimed, Inc.Multi-position infusion set device and process
US832114929 Jun 201127 Nov 2012Dexcom, Inc.Transcutaneous analyte sensor
US833200823 Mar 201011 Dic 2012Dexcom, Inc.System and methods for processing analyte sensor data
US833371410 Sep 200618 Dic 2012Abbott Diabetes Care Inc.Method and system for providing an integrated analyte sensor insertion device and data processing unit
US834309224 Nov 20091 Ene 2013Abbott Diabetes Care Inc.Method and system for providing integrated medication infusion and analyte monitoring system
US834309328 May 20101 Ene 2013Abbott Diabetes Care Inc.Fluid delivery device with autocalibration
US834496631 Ene 20061 Ene 2013Abbott Diabetes Care Inc.Method and system for providing a fault tolerant display unit in an electronic device
US834633618 Mar 20091 Ene 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US834633730 Jun 20091 Ene 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US834633827 Ene 20111 Ene 2013Dexcom, Inc.System and methods for replacing signal artifacts in a glucose sensor data stream
US835382921 Dic 200915 Ene 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US835709121 Dic 200922 Ene 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US836290418 Abr 201129 Ene 2013Abbott Diabetes Care Inc.Analyte monitoring system and methods
US836422918 May 200729 Ene 2013Dexcom, Inc.Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US836661430 Mar 20095 Feb 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US836991924 Oct 20085 Feb 2013Dexcom, Inc.Systems and methods for processing sensor data
US837200521 Dic 200912 Feb 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US837466716 Oct 200812 Feb 2013Dexcom, Inc.Signal processing for continuous analyte sensor
US838027311 Abr 200919 Feb 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US83860047 Sep 201126 Feb 2013Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US839194517 Mar 20095 Mar 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US83940211 Oct 200712 Mar 2013Dexcom, Inc.System and methods for processing analyte sensor data
US839652825 Mar 200812 Mar 2013Dexcom, Inc.Analyte sensor
US84091317 Mar 20072 Abr 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US84123019 Feb 20112 Abr 2013Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US841731224 Oct 20089 Abr 2013Dexcom, Inc.Systems and methods for processing sensor data
US842311324 Oct 200816 Abr 2013Dexcom, Inc.Systems and methods for processing sensor data
US84231141 Oct 200716 Abr 2013Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US842867816 May 201223 Abr 2013Dexcom, Inc.Calibration techniques for a continuous analyte sensor
US842867926 Mar 201023 Abr 2013Dexcom, Inc.System and methods for processing analyte sensor data
US843517927 Ene 20117 May 2013Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US844261021 Ago 200814 May 2013Dexcom, Inc.System and methods for processing analyte sensor data
US845236814 Ene 200928 May 2013Dexcom, Inc.Transcutaneous analyte sensor
US84563018 May 20084 Jun 2013Abbott Diabetes Care Inc.Analyte monitoring system and methods
US84577085 Dic 20084 Jun 2013Dexcom, Inc.Transcutaneous analyte sensor
US84619858 May 200811 Jun 2013Abbott Diabetes Care Inc.Analyte monitoring system and methods
US846335014 May 201011 Jun 2013Dexcom, Inc.Transcutaneous analyte sensor
US846542530 Jun 200918 Jun 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US846797228 Abr 201018 Jun 2013Abbott Diabetes Care Inc.Closed loop blood glucose control algorithm analysis
US846988623 Sep 200925 Jun 2013Dexcom, Inc.Signal processing for continuous analyte sensor
US847171430 Dic 201125 Jun 2013Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US847302131 Jul 200925 Jun 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US847322023 Ene 201225 Jun 2013Abbott Diabetes Care Inc.Method and device for early signal attenuation detection using blood glucose measurements
US84743976 May 20102 Jul 2013Dexcom, Inc.Transcutaneous analyte sensor
US847537317 Jul 20082 Jul 2013Dexcom, Inc.Transcutaneous analyte sensor
US848058019 Abr 20079 Jul 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US848379111 Abr 20089 Jul 2013Dexcom, Inc.Transcutaneous analyte sensor
US848379329 Oct 20109 Jul 2013Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US849147427 Ene 201123 Jul 2013Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US85098677 Feb 200613 Ago 2013Cercacor Laboratories, Inc.Non-invasive measurement of analytes
US850987128 Oct 200813 Ago 2013Dexcom, Inc.Sensor head for use with implantable devices
US851223920 Abr 200920 Ago 2013Abbott Diabetes Care Inc.Glucose measuring device for use in personal area network
US851224330 Sep 200520 Ago 2013Abbott Diabetes Care Inc.Integrated introducer and transmitter assembly and methods of use
US851224615 Mar 201020 Ago 2013Abbott Diabetes Care Inc.Method and apparatus for providing peak detection circuitry for data communication systems
US851551610 Mar 200520 Ago 2013Dexcom, Inc.Transcutaneous analyte sensor
US851551926 Feb 200920 Ago 2013Dexcom, Inc.Transcutaneous analyte sensor
US854318420 Oct 201124 Sep 2013Dexcom, Inc.Silicone based membranes for use in implantable glucose sensors
US854540328 Dic 20061 Oct 2013Abbott Diabetes Care Inc.Medical device insertion
US854855114 May 20101 Oct 2013Dexcom, Inc.Transcutaneous analyte sensor
US854855322 Jun 20121 Oct 2013Dexcom, Inc.System and methods for processing analyte sensor data
US856003726 Mar 201015 Oct 2013Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US856003917 Sep 200915 Oct 2013Dexcom, Inc.Particle-containing membrane and particulate electrode for analyte sensors
US856008230 Ene 200915 Oct 2013Abbott Diabetes Care Inc.Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
US85625585 Jun 200822 Oct 2013Dexcom, Inc.Integrated medicament delivery device for use with continuous analyte sensor
US85658487 May 200922 Oct 2013Dexcom, Inc.Transcutaneous analyte sensor
US856584914 May 201022 Oct 2013Dexcom, Inc.Transcutaneous analyte sensor
US857162429 Dic 200429 Oct 2013Abbott Diabetes Care Inc.Method and apparatus for mounting a data transmission device in a communication system
US857162514 May 201029 Oct 2013Dexcom, Inc.Transcutaneous analyte sensor
US85798167 Ene 201012 Nov 2013Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US857985331 Oct 200612 Nov 2013Abbott Diabetes Care Inc.Infusion devices and methods
US858559110 Jul 201019 Nov 2013Abbott Diabetes Care Inc.Method and system for providing basal profile modification in analyte monitoring and management systems
US858888216 Dic 200919 Nov 2013Dexcom, Inc.System and methods for processing analyte sensor data
US859145520 Feb 200926 Nov 2013Dexcom, Inc.Systems and methods for customizing delivery of sensor data
US85931093 Nov 200926 Nov 2013Abbott Diabetes Care Inc.Method and system for powering an electronic device
US859328720 Jul 201226 Nov 2013Abbott Diabetes Care Inc.Analyte monitoring system and methods
US85971893 Mar 20093 Dic 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US859757523 Jul 20123 Dic 2013Abbott Diabetes Care Inc.Analyte monitoring devices and methods therefor
US86029917 Jun 201010 Dic 2013Abbott Diabetes Care Inc.Analyte sensor introducer and methods of use
US86119787 Ene 201017 Dic 2013Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US861215916 Feb 200417 Dic 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US861370329 May 200824 Dic 2013Abbott Diabetes Care Inc.Insertion devices and methods
US861389230 Jun 200924 Dic 2013Abbott Diabetes Care Inc.Analyte meter with a moveable head and methods of using the same
US861528222 Feb 200624 Dic 2013Dexcom, Inc.Analyte sensor
US861707121 Jun 200731 Dic 2013Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US862290325 May 20127 Ene 2014Abbott Diabetes Care Inc.Continuous glucose monitoring system and methods of use
US862290511 Dic 20097 Ene 2014Dexcom, Inc.System and methods for processing analyte sensor data
US862290621 Dic 20097 Ene 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US862849830 Jun 201114 Ene 2014Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US863822023 May 201128 Ene 2014Abbott Diabetes Care Inc.Method and apparatus for providing data communication in data monitoring and management systems
US864161921 Dic 20094 Feb 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US864167419 Sep 20124 Feb 2014Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US864726920 Abr 200911 Feb 2014Abbott Diabetes Care Inc.Glucose measuring device for use in personal area network
US86498413 Abr 200711 Feb 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US865204320 Jul 201218 Feb 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US865397721 Jun 201318 Feb 2014Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US865774516 Oct 200825 Feb 2014Dexcom, Inc.Signal processing for continuous analyte sensor
US86577475 Abr 201125 Feb 2014Dexcom, Inc.Systems and methods for processing analyte sensor data
US866062717 Mar 200925 Feb 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US866310929 Mar 20104 Mar 2014Dexcom, Inc.Transcutaneous analyte sensor
US866353830 Jun 20114 Mar 2014Picolife Technologies, LlcMethod of making a membrane for use with a flow control system for a micropump
US866509130 Jun 20094 Mar 2014Abbott Diabetes Care Inc.Method and device for determining elapsed sensor life
US866646916 Nov 20074 Mar 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US86686453 Ene 200311 Mar 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US867081530 Abr 200711 Mar 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US867284427 Feb 200418 Mar 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US867284525 Mar 201018 Mar 2014Dexcom, Inc.Systems and methods for processing analyte sensor data
US867628711 Dic 200918 Mar 2014Dexcom, Inc.System and methods for processing analyte sensor data
US867651321 Jun 201318 Mar 2014Abbott Diabetes Care Inc.Method and device for early signal attenuation detection using blood glucose measurements
US868818830 Jun 20091 Abr 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US869077511 Abr 20088 Abr 2014Dexcom, Inc.Transcutaneous analyte sensor
US87001178 Dic 200915 Abr 2014Dexcom, Inc.System and methods for processing analyte sensor data
US872154522 Mar 201013 May 2014Dexcom, Inc.Transcutaneous analyte sensor
US872158530 Mar 201213 May 2014Dex Com, Inc.Integrated delivery device for continuous glucose sensor
US873163022 Mar 201020 May 2014Dexcom, Inc.Transcutaneous analyte sensor
US873218815 Feb 200820 May 2014Abbott Diabetes Care Inc.Method and system for providing contextual based medication dosage determination
US873434630 Abr 200727 May 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US873434817 Mar 200927 May 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US87381093 Mar 200927 May 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US87445453 Mar 20093 Jun 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US874731523 Sep 200910 Jun 2014Dexcom. Inc.Signal processing for continuous analyte sensor
US87509552 Nov 200910 Jun 2014Dexcom, Inc.Analyte sensor
US876185627 Abr 201224 Jun 2014Dexcom, Inc.System and methods for processing analyte sensor data
US876465730 Mar 20121 Jul 2014Abbott Diabetes Care Inc.Medical device inserters and processes of inserting and using medical devices
US876505927 Oct 20101 Jul 2014Abbott Diabetes Care Inc.Blood glucose tracking apparatus
US877118316 Feb 20058 Jul 2014Abbott Diabetes Care Inc.Method and system for providing data communication in continuous glucose monitoring and management system
US877118731 May 20118 Jul 2014Dexcom, Inc.System and methods for processing analyte sensor data
US87712291 Dic 20118 Jul 2014Picolife Technologies, LlcCartridge system for delivery of medicament
US877488724 Mar 20078 Jul 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US877488820 Ene 20108 Jul 2014Dexcom, Inc.System and methods for processing analyte sensor data
US87778534 Abr 201215 Jul 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US878800611 Dic 200922 Jul 2014Dexcom, Inc.System and methods for processing analyte sensor data
US87880078 Mar 201222 Jul 2014Dexcom, Inc.Transcutaneous analyte sensor
US878800831 May 201122 Jul 2014Dexcom, Inc.System and methods for processing analyte sensor data
US879026014 Oct 200929 Jul 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US87903079 Feb 201229 Jul 2014Picolife Technologies, LlcDrug delivery device and methods therefor
US879295319 Mar 201029 Jul 2014Dexcom, Inc.Transcutaneous analyte sensor
US879295419 Mar 201029 Jul 2014Dexcom, Inc.Transcutaneous analyte sensor
US87929559 Jun 201129 Jul 2014Dexcom, Inc.Transcutaneous analyte sensor
US879517714 Ene 20095 Ago 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US879893423 Jul 20105 Ago 2014Abbott Diabetes Care Inc.Real time management of data relating to physiological control of glucose levels
US880161024 Jul 200912 Ago 2014Dexcom, Inc.Signal processing for continuous analyte sensor
US880161122 Mar 201012 Ago 2014Dexcom, Inc.Transcutaneous analyte sensor
US880161227 Abr 201212 Ago 2014Dexcom, Inc.System and methods for processing analyte sensor data
US880716930 Jun 201119 Ago 2014Picolife Technologies, LlcFlow control system for a micropump
US880818227 Abr 201219 Ago 2014Dexcom, Inc.System and methods for processing analyte sensor data
US88082285 Jun 200819 Ago 2014Dexcom, Inc.Integrated medicament delivery device for use with continuous analyte sensor
US881207217 Abr 200819 Ago 2014Dexcom, Inc.Transcutaneous medical device with variable stiffness
US88120731 Jun 201019 Ago 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US88214009 Feb 20112 Sep 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US882512714 May 20102 Sep 2014Dexcom, Inc.Transcutaneous analyte sensor
US884055326 Feb 200923 Sep 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US88431871 Jun 201023 Sep 2014Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US884553611 Abr 200730 Sep 2014Dexcom, Inc.Transcutaneous analyte sensor
US885210130 Sep 20097 Oct 2014Abbott Diabetes Care Inc.Method and apparatus for providing analyte sensor insertion
US885843410 Mar 200514 Oct 2014Dexcom, Inc.Transcutaneous analyte sensor
US886219817 Dic 201214 Oct 2014Abbott Diabetes Care Inc.Method and system for providing an integrated analyte sensor insertion device and data processing unit
US888013718 Abr 20034 Nov 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US888627222 Feb 200611 Nov 2014Dexcom, Inc.Analyte sensor
US88862737 Nov 200811 Nov 2014Dexcom, Inc.Analyte sensor
US891136915 Dic 200816 Dic 2014Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US89158493 Feb 200923 Dic 2014Dexcom, Inc.Transcutaneous analyte sensor
US891585028 Mar 201423 Dic 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US892031928 Dic 201230 Dic 2014Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US892658530 Mar 20126 Ene 2015Dexcom, Inc.Integrated delivery device for continuous glucose sensor
US892996819 Jul 20106 Ene 2015Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US89302033 Feb 20106 Ene 2015Abbott Diabetes Care Inc.Multi-function analyte test device and methods therefor
US893366425 Nov 201313 Ene 2015Abbott Diabetes Care Inc.Method and system for powering an electronic device
US8971981 *31 Jul 20083 Mar 2015Roche Diagnostics Operations, Inc.Device and method for facilitating infusion of therapeutic fluids and sensing of bodily analytes
US89743861 Nov 200510 Mar 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US898620913 Jul 201224 Mar 2015Dexcom, Inc.Transcutaneous analyte sensor
US898983310 Mar 200524 Mar 2015Dexcom, Inc.Transcutaneous analyte sensor
US899333131 Ago 201031 Mar 2015Abbott Diabetes Care Inc.Analyte monitoring system and methods for managing power and noise
US900092922 Nov 20137 Abr 2015Abbott Diabetes Care Inc.Analyte monitoring system and methods
US901133129 Dic 200421 Abr 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US901133230 Oct 200721 Abr 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US90147737 Mar 200721 Abr 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US902057210 Sep 201028 Abr 2015Dexcom, Inc.Systems and methods for processing, transmitting and displaying sensor data
US903576730 May 201319 May 2015Abbott Diabetes Care Inc.Analyte monitoring system and methods
US90399752 Dic 201326 May 2015Abbott Diabetes Care Inc.Analyte monitoring devices and methods therefor
US90429532 Mar 200726 May 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US904419910 Mar 20052 Jun 2015Dexcom, Inc.Transcutaneous analyte sensor
US905590114 Sep 201216 Jun 2015Dexcom, Inc.Transcutaneous analyte sensor
US906074219 Mar 201023 Jun 2015Dexcom, Inc.Transcutaneous analyte sensor
US906410730 Sep 201323 Jun 2015Abbott Diabetes Care Inc.Infusion devices and methods
US90666943 Abr 200730 Jun 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US906669512 Abr 200730 Jun 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US906669727 Oct 201130 Jun 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US906670917 Mar 201430 Jun 2015Abbott Diabetes Care Inc.Method and device for early signal attenuation detection using blood glucose measurements
US907247721 Jun 20077 Jul 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US907860717 Jun 201314 Jul 2015Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US907860813 Jul 201214 Jul 2015Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US907862631 Mar 201114 Jul 2015Dexcom, Inc.Transcutaneous analyte sensor
US909529027 Feb 20124 Ago 2015Abbott Diabetes Care Inc.Method and apparatus for providing rolling data in communication systems
US9101303 *18 Ago 201011 Ago 2015Abbott Diabetes Care Inc.Analyte sensor ports
US910762315 Abr 200918 Ago 2015Dexcom, Inc.Signal processing for continuous analyte sensor
US9125603 *11 Ago 20098 Sep 2015Abbott Diabetes Care Inc.Analyte sensor ports
US912560418 May 20118 Sep 2015Arkray, Inc.Electrochemical sensor
US913540224 Oct 200815 Sep 2015Dexcom, Inc.Systems and methods for processing sensor data
US914356920 Feb 200922 Sep 2015Dexcom, Inc.Systems and methods for processing, transmitting and displaying sensor data
US91492199 Feb 20116 Oct 2015Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US914923313 Jun 20126 Oct 2015Dexcom, Inc.Systems and methods for processing sensor data
US914923413 Jun 20126 Oct 2015Dexcom, Inc.Systems and methods for processing sensor data
US915549618 Feb 201113 Oct 2015Dexcom, Inc.Low oxygen in vivo analyte sensor
US917745610 Jun 20133 Nov 2015Abbott Diabetes Care Inc.Analyte monitoring system and methods
US918609824 Mar 201117 Nov 2015Abbott Diabetes Care Inc.Medical device inserters and processes of inserting and using medical devices
US919232823 Sep 200924 Nov 2015Dexcom, Inc.Signal processing for continuous analyte sensor
US921599224 Mar 201122 Dic 2015Abbott Diabetes Care Inc.Medical device inserters and processes of inserting and using medical devices
US92204499 Jul 201329 Dic 2015Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US922670128 Abr 20105 Ene 2016Abbott Diabetes Care Inc.Error detection in critical repeating data in a wireless sensor system
US92479004 Jun 20132 Feb 2016Dexcom, Inc.Analyte sensor
US92479012 Ago 20062 Feb 2016Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US925917523 Oct 200616 Feb 2016Abbott Diabetes Care, Inc.Flexible patch for fluid delivery and monitoring body analytes
US926545324 Mar 201123 Feb 2016Abbott Diabetes Care Inc.Medical device inserters and processes of inserting and using medical devices
US928292525 Mar 201015 Mar 2016Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US931419531 Ago 201019 Abr 2016Abbott Diabetes Care Inc.Analyte signal processing device and methods
US93141967 Sep 201219 Abr 2016Dexcom, Inc.System and methods for processing analyte sensor data for sensor calibration
US93141983 Abr 201519 Abr 2016Abbott Diabetes Care Inc.Analyte monitoring system and methods
US932046129 Sep 201026 Abr 2016Abbott Diabetes Care Inc.Method and apparatus for providing notification function in analyte monitoring systems
US932389815 Nov 201326 Abr 2016Abbott Diabetes Care Inc.Method and system for providing basal profile modification in analyte monitoring and management systems
US932671429 Jun 20103 May 2016Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US93267165 Dic 20143 May 2016Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US932837116 Jul 20133 May 2016Dexcom, Inc.Sensor head for use with implantable devices
US933293329 Sep 201410 May 2016Abbott Diabetes Care Inc.Method and apparatus for providing analyte sensor insertion
US933294431 Ene 201410 May 2016Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US933922231 May 201317 May 2016Dexcom, Inc.Particle-containing membrane and particulate electrode for analyte sensors
US933923816 May 201217 May 2016Dexcom, Inc.Systems and methods for processing sensor data
US935166812 Oct 200931 May 2016Dexcom, Inc.Signal processing for continuous analyte sensor
US935166930 Sep 201031 May 2016Abbott Diabetes Care Inc.Interconnect for on-body analyte monitoring device
US936417323 Sep 200914 Jun 2016Dexcom, Inc.Signal processing for continuous analyte sensor
US93809715 Dic 20145 Jul 2016Abbott Diabetes Care Inc.Method and system for powering an electronic device
US939888210 Sep 200626 Jul 2016Abbott Diabetes Care Inc.Method and apparatus for providing analyte sensor and data processing device
US94025441 Feb 20102 Ago 2016Abbott Diabetes Care Inc.Analyte sensor and apparatus for insertion of the sensor
US940257011 Dic 20122 Ago 2016Abbott Diabetes Care Inc.Analyte sensor devices, connections, and methods
US941477710 Mar 200516 Ago 2016Dexcom, Inc.Transcutaneous analyte sensor
US94209651 Jul 201123 Ago 2016Dexcom, Inc.Signal processing for continuous analyte sensor
US94209684 Abr 201223 Ago 2016Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US942718312 Jul 201130 Ago 2016Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US944619426 Mar 201020 Sep 2016Dexcom, Inc.Methods and systems for promoting glucose management
US945190819 Dic 201227 Sep 2016Dexcom, Inc.Analyte sensor
US945191027 Ago 201027 Sep 2016Dexcom, Inc.Transcutaneous analyte sensor
US947781123 Jun 200525 Oct 2016Abbott Diabetes Care Inc.Blood glucose tracking apparatus and methods
US948042119 Ago 20131 Nov 2016Abbott Diabetes Care Inc.Integrated introducer and transmitter assembly and methods of use
US949815516 Oct 200822 Nov 2016Dexcom, Inc.Signal processing for continuous analyte sensor
US949815930 Oct 200722 Nov 2016Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US950441315 Abr 201329 Nov 2016Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US95107824 Abr 20126 Dic 2016Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US952196830 Sep 200520 Dic 2016Abbott Diabetes Care Inc.Analyte sensor retention mechanism and methods of use
US953894625 Mar 201010 Ene 2017Dexcom, Inc.Integrated receiver for continuous analyte sensor
US954969325 Jul 201324 Ene 2017Dexcom, Inc.Silicone based membranes for use in implantable glucose sensors
US957253428 Jun 201121 Feb 2017Abbott Diabetes Care Inc.Devices, systems and methods for on-skin or on-body mounting of medical devices
US95749143 Mar 201421 Feb 2017Abbott Diabetes Care Inc.Method and device for determining elapsed sensor life
US957905326 Mar 201028 Feb 2017Dexcom, Inc.Dual electrode system for a continuous analyte sensor
US95856074 Abr 20127 Mar 2017Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US960355713 May 201328 Mar 2017Dexcom, Inc.Transcutaneous analyte sensor
US961003113 Abr 20114 Abr 2017Dexcom, Inc.Transcutaneous analyte sensor
US96100349 Nov 20154 Abr 2017Abbott Diabetes Care Inc.Analyte monitoring device and methods of use
US962541319 May 201518 Abr 2017Abbott Diabetes Care Inc.Analyte monitoring devices and methods therefor
US963606824 Jun 20162 May 2017Abbott Diabetes Care Inc.Analyte sensor and apparatus for insertion of the sensor
US964905711 May 201516 May 2017Abbott Diabetes Care Inc.Analyte monitoring system and methods
US964906929 Jun 201616 May 2017Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US966867726 Oct 20156 Jun 2017Dexcom, Inc.Analyte sensor
US966868218 Dic 20146 Jun 2017Dexcom, Inc.Transcutaneous analyte sensor
US966916216 Mar 20166 Jun 2017Abbott Diabetes Care Inc.Method and system for providing basal profile modification in analyte monitoring and management systems
US968718330 Mar 201227 Jun 2017Abbott Diabetes Care Inc.Medical device inserters and processes of inserting and using medical devices
US969371327 Jun 20164 Jul 2017Abbott Diabetes Care Inc.Analyte sensor devices, connections, and methods
US971744915 Ene 20131 Ago 2017Dexcom, Inc.Systems and methods for processing sensor data
US972402824 Nov 20148 Ago 2017Dexcom, Inc.Analyte sensor
US97240456 Abr 20178 Ago 2017Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US973058410 Feb 201415 Ago 2017Abbott Diabetes Care Inc.Glucose measuring device for use in personal area network
US97411399 Ago 201322 Ago 2017Dexcom, Inc.Integrated medicament delivery device for use with continuous analyte sensor
US974386229 Mar 201229 Ago 2017Abbott Diabetes Care Inc.Systems and methods for transcutaneously implanting medical devices
US97438631 Jun 201629 Ago 2017Abbott Diabetes Care Inc.Method and system for powering an electronic device
US97504398 Abr 20165 Sep 2017Abbott Diabetes Care Inc.Method and apparatus for providing notification function in analyte monitoring systems
US975044012 Abr 20165 Sep 2017Abbott Diabetes Care Inc.Method and system for providing data management in data monitoring system
US975044115 Ago 20165 Sep 2017Dexcom, Inc.Signal processing for continuous analyte sensor
US975044427 Abr 20165 Sep 2017Abbott Diabetes Care Inc.Interconnect for on-body analyte monitoring device
US975046014 Abr 20175 Sep 2017Dexcom, Inc.Systems and methods for replacing signal artifacts in a glucose sensor data stream
US97570611 Sep 201512 Sep 2017Dexcom, Inc.Low oxygen in vivo analyte sensor
US97636092 Ene 201319 Sep 2017Dexcom, Inc.Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US977554330 Dic 20133 Oct 2017Dexcom, Inc.Transcutaneous analyte sensor
US977556321 Sep 20163 Oct 2017Abbott Diabetes Care Inc.Integrated introducer and transmitter assembly and methods of use
US9788771 *23 Oct 200617 Oct 2017Abbott Diabetes Care Inc.Variable speed sensor insertion devices and methods of use
US979533128 Abr 201624 Oct 2017Abbott Diabetes Care Inc.Method and apparatus for providing analyte sensor insertion
US980154530 Jul 201531 Oct 2017Abbott Diabetes Care Inc.Method and apparatus for providing rolling data in communication systems
US980157218 Jun 201531 Oct 2017Dexcom, Inc.Transcutaneous analyte sensor
US98041142 Mar 201631 Oct 2017Dexcom, Inc.Sensor head for use with implantable devices
US980818626 Sep 20147 Nov 2017Abbott Diabetes Care Inc.Method and system for providing an integrated analyte sensor insertion device and data processing unit
US981441430 Mar 201014 Nov 2017Dexcom, Inc.Transcutaneous analyte sensor
US20020077599 *18 Dic 200120 Jun 2002Animas CorporationTranscutaneous inserter for low-profile infusion sets
US20030158520 *20 Feb 200321 Ago 2003Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US20030199823 *18 Abr 200323 Oct 2003Minimed Inc.Insertion device for an insertion set and method of using the same
US20030225373 *14 Mar 20034 Dic 2003Minimed, Inc.Insertion device for an insertion set and method of using the same
US20040002682 *9 Dic 20021 Ene 2004Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US20040106163 *10 Jul 20033 Jun 2004Workman Jerome JamesNon-invasive measurement of analytes
US20050101910 *10 Nov 200312 May 2005Medtronic Minimed, Inc.Subcutaneous infusion set
US20060129090 *3 Dic 200415 Jun 2006Medtronic Minimed, Inc.Multi-position infusion set device and process
US20060129123 *25 Ene 200615 Jun 2006Steven WojcikTranscutaneous inserter for low-profile infusion sets
US20070020181 *7 Feb 200625 Ene 2007Workman Jerome JNon-invasive measurement of analytes
US20070142776 *9 Dic 200221 Jun 2007Medtronic Minimed, Inc.Insertion device for an insertion set and method of using the same
US20090163878 *27 Ene 200925 Jun 2009Medtronic Minimed, Inc.Multi-position infusion set device and process
US20090247984 *24 Oct 20081 Oct 2009Masimo Laboratories, Inc.Use of microneedles for small molecule metabolite reporter delivery
US20100137695 *31 Jul 20083 Jun 2010Ofer YodfatDevice for method facilitating infusion of therapeutic fluids and sensing of bodily analytes
US20110040164 *18 Ago 201017 Feb 2011Analyte Sensor PortsAnalyte Sensor Ports
US20110040246 *11 Ago 200917 Feb 2011Galasso John RAnalyte sensor ports
US20110040256 *9 Sep 201017 Feb 2011Medtronic Minimed, Inc.Insertion Device for an Insertion Set and Method of Using the Same
US20130274576 *16 Abr 201217 Oct 2013PicoLife TechnologiesMedication delivery device with multi-reservoir cartridge system and related methods of use
USRE4339913 Jun 200822 May 2012Dexcom, Inc.Electrode systems for electrochemical sensors
USRE446951 May 20127 Ene 2014Dexcom, Inc.Dual electrode system for a continuous analyte sensor
EP1389138A2 *2 Abr 200218 Feb 2004Medtronic MiniMed, Inc.Insertion device for an insertion set and method of using the same
EP1389138A4 *2 Abr 20024 Abr 2007Medtronic Minimed IncInsertion device for an insertion set and method of using the same
EP2322094A1 *13 Jul 200518 May 2011DexCom, Inc.Transcutaneous analyte sensor
EP2327362A1 *13 Jul 20051 Jun 2011DexCom, Inc.Transcutaneous analyte sensor
EP2332466A1 *13 Jul 200515 Jun 2011DexCom, Inc.Transcutaneous analyte sensor
EP2335587A3 *13 Jul 20057 Sep 2011DexCom, Inc.Transcutaneous analyte sensor
WO2006017359A1 *13 Jul 200516 Feb 2006Dexcom, Inc.Transcutaneous analyte sensor with variable stiffness
WO2011019658A1 *9 Ago 201017 Feb 2011Abbott Diabetes Care Inc.Analyte sensor ports
WO2013158431A1 *10 Abr 201324 Oct 2013PicoLife TechnologiesMedication delivery device with multi-reservoir cartridge system and related methods of use
Clasificaciones
Clasificación de EE.UU.439/834
Clasificación internacionalA61B17/34, A61B5/00, A61M25/06, A61M5/158, A61B5/1473, A61B5/145
Clasificación cooperativaY10S439/909, A61B5/6849, A61B2017/3492, A61B5/14532, A61M2005/1581, A61M25/0612, A61M2005/1587
Clasificación europeaA61B5/145G, A61B5/68D1B2