US20040060845A1 - Press-through pack, sealing sheet for press-through pack, and preparation method of tablet - Google Patents
Press-through pack, sealing sheet for press-through pack, and preparation method of tablet Download PDFInfo
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- US20040060845A1 US20040060845A1 US10/663,690 US66369003A US2004060845A1 US 20040060845 A1 US20040060845 A1 US 20040060845A1 US 66369003 A US66369003 A US 66369003A US 2004060845 A1 US2004060845 A1 US 2004060845A1
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- United States
- Prior art keywords
- sheet
- sealing sheet
- accommodation body
- pack
- press
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0007—Pill breaking or crushing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
- B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D2575/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D2575/3209—Details
- B65D2575/3218—Details with special means for gaining access to the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
- B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D2575/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D2575/3209—Details
- B65D2575/3218—Details with special means for gaining access to the contents
- B65D2575/3245—Details with special means for gaining access to the contents by peeling off the non-rigid sheet
Abstract
A press-through pack and a sealing sheet for use in the same capable of easily taking out solid material such as tablet or the like contained storage recesses by only pushing action of fingers. The pack comprises an accommodation body (2) with plural storage recesses (2 a) defined by sheet like portions (2 b) for a containing solid material therein and sealing sheet (5). The sealing sheet (5) is made of such material that a recess (2 a) in which solid material (T) contained, is partly ruptured without causing floating and peeling at the adhesion portion of the adhesive layer (4) and the sheet like portions (2 b) when pushing the projecting portion (2 c) of the outer side of the recess (2 a) with fingers, whereby the solid material (T) contained in the recess (2 a) is easily taken out and the sealing sheet is partially bonded to the accommodation body at sheet like portions (2 b) in a manner that the whole parts of sealing sheet (5) is easily peeled off from the accommodation body.
Description
- The present invention relates to a press-through pack, a sealing sheet for a press-through pack and a taking-out method of tablet. Specifically, it relates to a press-through pack wherein a solid material such as a tablet or the like contained therein can be taken out easily one by one and also plural solid materials or all solid materials are taken out at one time if desired, a sealing sheet appropriate for producing such a press-through pack, and a taking-out method of tablets wherein all dividable tablets contained in the press-through pack can be divided at one time and all of the divided tablets in each storage recess of an accommodation body can be obtained at one time.
- A press-through pack (generally called as PTP package) can contain a solid material one by one in each storage recess (or pocket) tightly and hygienically sealed and a solid material contained in the storage recess can be easily obtained one by one. Therefore, such a press-through pack has been widely used for individually packing medicines such as a tablet and a capsule, and confections such as a candy.
- FIG. 7 shows a sectional view of one embodiment of such a press-through pack. The press-through pack101 is provided with an
accommodation body 102 and asealing sheet 105 and is constructed such that anadhesive layer 104 of thesealing sheet 105 is bonded to sheet likeportions 102 b, . . . 102 b of theaccommodation body 102. - The
accommodation body 102 is made of synthetic resin such as polyvinyl chloride, polypropylene and cyclic polyolefin and plural storage recess 102 a, . . . 102 a generally formed according to the shape of solid materials T, . . . T to be contained are connected to the sheet likeportions 102 b, . . . 102 b. - The
sealing sheet 105 has asubstrate 103 made of aluminum foil or the like and anadhesive layer 104 provided on one surface of thesubstrate 103. - According to the press-through pack101, the
adhesive layer 104 of thesealing sheet 105 and the sheet likeportions 102 b, . . . 102 b of theaccommodation body 102 are bonded while containing the solid materials T, . . . T in theplural storage recesses 102 a, . . . 102 a of theaccommodation body 102 respectively, and theaccommodation body 102 is tightly sealed by thesealing sheet 105. - According to such a press-through pack101, when each projecting
portion 102 c, . . . 102 c as outer surface of each storage recess 102 a, . . . 102 a is pressed, areas R1, . . . R1 of thesealing sheet 105 tightly sealing each storage recess 102 a, . . . 102 a are ruptured by solid materials T, . . . T contained in each of thestorage recesses 102 a, . . . 102 a, thereby the solid materials T, . . . T can be obtained out of the press-through pack 101 one by one. - On the other hand, the dosage amount of medicine is required to be varied depending on the weight, age and so on of the patient to be dosed. Therefore, many tablets are provided with a dividing line along which the tablets are easily divided by fingers or tools.
- However, the prior press-through pack101 is designed such that the solid materials T, . . . T each contained in the
recesses 102 a, . . . 102 a are obtained one by one. Therefore, when medicine containing plural different components is dividedly packed for one dosage to a patient at a hospital, a clinic or a pharmacy, a pharmacist takes the solid materials T, . . . T out of the press-through pack 101 one by one and the removed solid materials T, . . . T are dividedly packed for one dosage by means of a dividedly packing machine. It takes trouble and time for taking the solid materials T, . . . T out of the press-through pack 101 one by one. It is requested by a pharmacist and an administrator at a medical site to provide a press-through pack by which the solid materials T. T can be obtained one by one and also easily all the solid materials T, . . . T can be obtained at one time. - Aluminum foil is widely used as the
substrate 103 of the sealingseat 105 because it is highly dampproof, the solid materials T can be easily obtained, and it is posh. However, thealuminum substrate 103 and theaccommodation body 102 aren't separately disposed after all the solid materials T, . . . T are taken out of the press-through pack 101 so that the treatment of disposed materials is difficult and they aren't recycled. - The present invention is proposed to meet the above-mentioned request.
- Accordingly, an object of the invention is to provide a press-through pack by which the solid materials stored therein can easily be obtained one by one, plural solid materials or all of the solid materials can be obtained at one time and which can be disposed after separating a sealing sheet and an accommodation body. And it is also an object of the invention to provide a sealing sheet which can easily make such a press-through pack.
- Many dividable tablets are obtained from a press-through pack101 one by one and each one is manually divided. Such a work takes a lot of troubles and long time although they have dividing lines so as to be easily divided by a punch as mentioned above. It is expected by pharmacists for a long time to propose a taking-out method of tablets wherein a large amount of tablets are divided at one time and the divided tablets are easily gathered at one time in order to improve efficiency of dispensation work.
- A further object of the present invention for satisfying the pharmacist's request is to provide a taking-out method wherein dividable tablets contained in a press-through pack are taken out one by one, also a lot of the dividable tablets are divided at one time, and the divided tablets are gathered at one time.
- According to the claim 1 of the present invention, a press-through pack comprised of an accommodation body having plural storage recesses provided with sheet like portions therebetween, and a sealing sheet having a substrate on which one surface side an adhesive layer is formed, said accomodation body being sealed tightly by said sealing sheet in a manner that said adhesive layer and said sheet like portions are bonded to each other with a solid material contained in each of said plural storage recesses wherein, said sealing sheet is made of such material that the part of said sealing sheet responding to said recess, a part in which a solid material is contained, is partly ruptured without causing floating and peeling of adhesion portion between said adhesive layer of said sealing sheet and said sheet like portion of said accommodation body when pushing the projecting portion of the outer side of said recess with fingers, whereby said solid material contained in said recess is taken out and said sealing sheet is further bonded to said sheet like portions of said accommodation body in a manner that said sealing sheet is easily peeled off from said accommodation body.
- Here “the sealing sheet is further bonded to the sheet like portions of the accommodation body in a manner that the sealing sheet is easily peeled off from the accommodation body” means the sealing sheet is bonded to the sheet like portion of the accommodation body so that the sealing sheet is exfoliated from the sheet like portion of the accommodation body easily and without being ruptured when a part of the sealing sheet of the press-through pack is peeled off.
- The material of the accommodation body or the substrate of the sealing sheet isn't limited if it can be used for a press-through pack for packing pharmaceuticals, drugs for animals and plants, confections, health foods, fishing baits, toys and so on.
- The press-through pack of the
claim 2 of the present invention is characterized in that the solid material is a dividable tablet. - More than one dividable tablet may be contained in any of the storage recesses of the accommodation body of the press-through pack. The dividable tablet may be contained in the storage recess in such a manner the surface having a dividing line faces the accommodation body or the surface opposite to the one having a dividing line faces the accommodation body. Further, those tablets may be mixed at random.
- “A dividable tablet” preferably has a dividing line at the center of the surface thereof and can be divided along the dividing line when pressure is applied on the surface or the back of the tablet so that the force is concentrated on the dividing line. More specifically, it is preferable to use a dividable tablet which has a dividing line at its center of the surface and at least one of the surface having a dividing line or its opposite surface may be formed concave or convex.
- Such a dividable tablet may be a naked tablet (uncoated tablet) or a coated tablet which is appropriately coated with coating material on the naked tablet.
- The diameter of a dividable tablet is preferably from 3 mm to 30 mm and more preferably from 5 mm to 12 mm.
- The tabletting pressure for manufacturing a dividable tablet is preferably not more than 50N of pressure in the thickness direction when the tablet is divided and more preferably from 15N to 40N.
- According to the press-through pack of the
claim 3 of the present invention, the bonding strength of the sealing sheet and the sheet like portion of the accommodation body in the press-through pack of theclaim 1 or 2 is not less than 0.9N/15 mm width and not more than 3.1N/15 mm width in T peeling test executed at a peeling speed of 200 mm/min. - The unit “N/15 mm width” used in the specification means peeling strength when T peeling test is executed wherein the accommodation body and the sealing sheet are bonded, thereafter the bonded portion thereof is cut into 15 mm width and the cut piece is used as a test sample.
- The term “T peeling test” means a test according to JIS (Japanese Industrial Standards) K6845.
- In the above-mentioned range, peeling or floating between the accommodation body and the sealing sheet isn't caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses (so called a pocket) from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing the projecting portions as outer surface of the storage recesses containing the solid materials into the sheet direction with fingers, and the sealing sheet is bonded to the sheet like portion of the accommodation body so as to be easily peeled from the accommodation body without the sealing sheet ruptured.
- Contrary under the above-mentioned range, the sealing sheet can be peeled off from the accommodation body without being broken. However, peeling or floating is caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing the projecting portions as outer surface of the storage recesses containing the solid materials into the sheet direction with fingers.
- Above the above-mentioned range, peeling or floating isn't caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing with fingers. However, it is difficult to peel off or exfoliate the sealing sheet from the accommodation body. When the sealing sheet is forcedly peeled off, a part of the sealing sheet is ruptured.
- The bonding strength of the bonded part between the sealing sheet and the sheet like portion of the accommodation body is preferably from 1.3N/15 mm width to 2.7N/15 mm width when T peeling test is carried out at a peeling speed of 200 mm/min.
- According to the press-through pack of the
claim 4 of the present invention, the bonding strength of the sealing sheet and the sheet like portion of the accommodation body in the press-through pack of theclaim 1 or 2 is not less than 4.2N/15 mm width and not more than 7.0N/15 mm width in T peeling test executed at a peeling speed of 100 mm/min. - In the above-mentioned range, peeling or floating isn't caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses (so called a pocket) from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing projecting portions as outer surface of the storage recesses containing solid materials into the sheet direction with fingers, and the sealing sheet is bonded to the sheet like portion of the. accommodation body so as to be easily exfoliated from the accommodation body without the sealing sheet ruptured.
- Contrary under the above-mentioned range, the sealing sheet can be peeled off from the accommodation body without being broken. However, peeling or floating is caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing the projecting portions as outer surface of the storage recesses containing the solid materials into the sheet direction with fingers.
- Above the above-mentioned range, peeling or floating isn't caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses from where solid materials are taken by breaking the sealing sheet tightly sealing the storage recesses by pushing with fingers. However, it is difficult to peel off or exfoliate the sealing sheet from the accommodation body. When the sealing sheet is forcedly peeled off, a part of the sealing sheet is ruptured.
- The bonding strength of the bonded part between the sealing sheet and the sheet like portion of the accommodation body is preferably from 4.8N/15 mm width to 6.5N/15 mm width in T peeling test executed at a peeling speed of 100 mm/min.
- According to the press-through pack of the
claim 5 of the present invention, an adhesion lowering component may be mixed for an adhesive component of the adhesive forming the adhesive layer of the sealing sheet of the press-through pack of any of the claims 1-4. - The “adhesive component” means an adhesive ordinarily used for heat sealing or cold sealing.
- The “adhesion lowering component” means a component for weakening the bonding strength of an adhesive component such as an adhesive with lower bonding strength or a component ordinarily used for a molding lubricant or a filler. A resin used for a molding lubricant is for example a silicone resin or fluorocarbon polymer. When the accommodation body is made of polyvinyl chloride, acrylic resin can be used as an adhesion lowering component.
- As a filler, pulverized powder such as silicon oxide, magnesium silicate, titanium oxide, zinc white, calcium carbonate, almina, and talk can be used.
- According to the press-through pack of the present invention, the bonding strength is adjusted by mixing an appropriate amount of bonding strength lowering component in an adhesive component so that peeling or floating isn't caused at the bonded portion of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet other than the storage recesses (so called a pocket) from where the solid materials are taken by breaking a part of the sealing sheet tightly sealing the storage recesses by pushing the projecting portions as outer surface of the storage recesses containing the solid materials into the sheet direction with fingers, and the sealing sheet is bonded to the sheet like portion of the accommodation body so as to be easily exfoliated from the accommodation body without the sealing sheet ruptured.
- According to the press-through pack of the claim 6 of the present invention, the adhesive layer of the sealing sheet may be coated on one surface of the sealing sheet of the press-through pack of any of the claims 1-5 by a partial coating method.
- As the “partial coating method”, various methods may be conceived, and an adhesive may be coated on the surface facing the accommodation body of the sealing sheet like cross lines or lines or both cross lines and lines only if the solid materials contained in the storage recesses can be completely sealed.
- According to such a press-through pack of the present invention, the bonding strength is adjusted by applying the adhesive partially so that peeling or floating isn't caused between the accommodation body and the sealing sheet other than the so-called pocket from where solid materials are taken by breaking a part of the sealing sheet tightly sealing the storage recesses by pushing the projecting portions as outer surface of the storage recesses containing the solid materials into the sheet direction with fingers, and the sealing sheet is bonded to the sheet like portion of the accommodation body so as to be easily peeled from the accommodation body without the sealing sheet ruptured.
- According to the sealing sheet for a press-through pack of any one of the claims 7-9 of the present invention, solid materials contained in a press-through pack can be taken out one by one and also plural solid materials or all the solid materials are taken out at one time if desired.
- The sealing sheet for a press-through pack of the claim 7 of the present invention is provided with a substrate and an adhesive layer on one surface of the substrate, said adhesive layer being bonded to a sheet like portion of an accommodation body having plural storage recesses with sheet like portions therebetween, and said sealing sheet tightly sealing the accommodation body wherein, said sealing sheet is made of such material that the part of said sealing sheet responding to said recess, a part in which a solid material is contained, is partly ruptured without causing floating and peeling of adhesion portion between said adhesive layer of the sealing sheet and said sheet like portion of the accommodation body when pushing the projecting portion of the outer side of said recess with fingers, whereby said solid material contained in said recess is taken out and said sealing sheet is further bonded to said sheet like portions of said accommodation body in a manner that said sealing sheet is easily peeled off from said accommodation body by fingers.
- According to the sealing sheet for the press-through pack according to the claim 8 of the present invention, the bonding strength of the sealing sheet for the press-through pack according to the claim 7 and the sheet like portion of the accommodation body is not less than 0.9N/15 mm width and not more than 3.1N/15 mm width in T peeling test executed at a peeling speed of 200 mm/min.
- More preferably, the bonding strength of the sealing sheet and the sheet like portion of the accommodation body is not less than 1.3N/15 mm width and not more than 2.7N/15 mm width in T peeling test executed at a peeling speed of 200 mm/min.
- According to the sealing sheet for the press-through pack according to the claim 9 of the present invention, the bonding strength of the sealing sheet for the press-through pack according to claim 7 and the sheet like portion of the accommodation body is not less than 4.2N/15 mm width and not more than 7.0N/15 mm width in T peeling test executed at a peeling speed of 100 mm/min.
- More preferably, the bonding strength of the sealing sheet and the sheet like portion of the accommodation body is not less than 4.8N/15 mm width and not more than 6.5 N/15 mm width when T peeling test is executed at a peeling speed of 100 mm/min.
- The taking-out method of tablets of the claim 10 of the present invention is characterized in that all dividable tablets contained in the press-through pack are divided at one time and the divided tablets are easily obtained at one time. According to such a method, the press-through pack according to the
claim 2 is placed on a flat plate and all dividable tablets contained in each storage recess of the accommodation body of the press-through pack are divided by applying an equal force from upward of the press-through pack placed on the flat plate by means of a flat plate, and the sealing sheet is peeled off the accommodation body and all the divided tablets contained in each storage recess of the accommodation body are obtained at once. - FIG. 1 is a sectional view of one embodiment of the press-through pack of the present invention.
- FIG. 2 is schematic diagram showing a dividing test for dividable tablets.
- FIG. 3 shows one example of a preferable dividable tablet to be contained in the storage recess of the accommodation body of the press-through pack of the present invention. FIG. 3(a) is its plane view, FIG. 3(b) is its back view, and FIG. 3(c) is its side view.
- FIG. 4 is another example of a preferable dividable tablet to be contained in the storage recess of the accommodation body of the press-through pack of the present invention. FIG. 4(a) is its plane view, FIG. 4(b) is its back view, and FIG. 4(c) is its side view.
- FIG. 5 is still further example of a preferable dividable tablet to be contained in the storage recess of the accommodation body of the press-through pack of the present invention. FIG. 5(a) is its plane view, FIG. 5(b) is its back view, and FIG. 5(c) is its side view.
- FIG. 6 is still another example of a preferable dividable tablet to be contained in the storage recess of the accommodation body of the press-through pack of the present invention. FIG. 6(a) is its plane view, FIG. 6(b) is its back view, and FIG. 6(c) is its side view.
- FIG. 7 is a sectional view showing one example of prior press-through pack.
- The present invention will be more detailed referring to the attached drawings.
- FIG. 1 shows a sectional view of one embodiment of the press-through pack of the present invention. The press-through pack1 is provided with an
accommodation body 2 and asealing sheet 5 and anadhesive layer 4 of the sealingsheet 5 is bonded to sheet likeportions 2 b, . . . 2 b of theaccommodation body 2. - The
accommodation body 2 is thermoformed according to the shape of solid materials T, . . . T to be contained and plural storage recesses 2 a, . . . 2 a are connected with the sheet likeportions 2 b, . . . 2 b. - The material for the
accommodation body 2 may be thermoplastic synthetic resin such as polyvinyl chloride, polypropylene, polystyrene, cyclic polyolefin and so on. When such a material is used for theaccommodation body 2, theplural storage recess 2 a, . . . 2 a can be easily thermoformed according to the shape of the solid materials T, . . . T to be contained. - The
sealing sheet 5 has asubstrate 3 and theadhesive layer 4 provided at one surface of thesubstrate 3. - Many kinds of packaging material can be used for the
substrate 3 of the sealingsheet 5 wherein the material can seal the solid materials T, . . . T to be contained in eachstorage recess 2 a, . . . 2 a of theaccommodation body 2 and can be easily ruptured by the contained solid materials T, . . . T when projectingportions 2 c, . . . 2 c as outer surface of the storage recesses 2 a, . . . 2 a are pushed into the direction of the sealingsheet 5. For example, aluminum foil, glassine paper, synthetic resin sheet containing a filler for easy breakage, a paper, and the like are exemplified. - When aluminum foil is used for the
substrate 3 of the sealingsheet 5, its thickness is preferably not less than 5 μm and not more than 30 μm, and more preferably it is a hard foil from 15 μm to 25 μm. - When glassine paper is used for the
substrate 3 of the sealingsheet 5, 30.5 g/m2 of basis weight (weight per m2) is preferable. - When synthetic resin sheet containing a filler for easy breakage is used for the
substrate 3 of the sealingsheet 5, its thickness is preferably from 9 μm to 100 μm, and more preferably from 12 μm to 80 μm. - Thermoplastic synthetic resin such as polyvinyl chloride, polypropylene, polystyrene, or striated polyolefin is preferably used as synthetic resin.
- There are silicon oxide, magnesium silicate, titanium oxide, zinc white, carcium carbonate, alumina, talc and the like as a filler contained in the synthetic resin. The average particle diameter is from 1 μm to 10 μm and the filler may be contained in the synthetic resin from 5 weight % to 15 weight %, more preferably from 5 weight % to 70 weight %.
- When paper is used for the
substrate 3 of the sealingsheet 5, the basis weight is preferably from 13 g/m2 to 100 g/m2. - The physical property and composition of the
substrate 3 of the sealingmaterial 5 are such that solid materials T can be taken out by breaking areas R1, . . . R1 sealing the storage recesses 2 a, . . . 2 a of the sealingsheet 5 which seal the storage recess, when the projectingportions 2 c as outer surface of the storage recesses 2 a containing the solid materials T are pushed by fingers. - Although the above-mentioned construction is the same as the prior press-through pack101, according to the press-through pack 1 of the present invention, the bonding strength of the
adhesive layer 4 of the sealingsheet 5 and the sheet likeportions 2 b, . . . 2 b of theaccommodation body 2 is adjusted such that breakage of the sealingsheet 5 doesn't spread to adhesive parts R2, . . . R2 of the sheet likeportion 2 b and theadhesive layer 4, and only the areas R1, . . . R1 of the sealing sheet 5 ( so called a pocket ) sealing the storage recesses 2 a, . . . 2 a are ruptured so that the solid materials T, . . . T can be taken out one by one when each projectingportion 2 c, . . . 2 c as outer surface of the storage recesses 2 a, . . . 2 a containing the solid materials T, . . . T is pushed in the direction of the sealingsheet 5 by fingers. It is also adjusted such that the sealingseat 5 can be easily separated from theaccommodation body 2 without being ruptured halfway. - Then adjustment method of bonding strength of the sealing
sheet 5 will be explained for the cases when the bonding strength of theadhesive layer 4 is adjusted by the component of the adhesive and when the bonding strength of the adhesive is adjusted by a coating method for thesubstrate 3 of the sealingsheet 5. - A. Case that Bonding Strength is Adjusted by the Component of Adhesive
- In this case appropriate amount of adhesion lowering component is included in the adhesive component.
- Any material can be used for the adhesive component if it can bond the
accommodation body 2 and thesubstrate 3 of the sealingsheet 5, and for example, thermoplastic resin capable of heat sealing or cold sealing adhesive capable of cold sealing may be used. - Vinyl chloride vinyl acetate copolymer can be preferably used as thermoplastic resin capable of heat sealing when the
accommodation body 2 is made of polyvinyl chloride, chlorinated polypropylene or carboxyl polypropylene is preferably used for theaccommodation body 2 made of polypropylene, and the mixture of vinyl chloride/vinyl acetate copolymer and acrylic acid resin is preferably used for theaccommodation body 2 made of polystyrene, however, the present invention isn't limited to such a material. - Acrylic acid resin, silicon resin, rubber or the like may be used as a cold sealing adhesive.
- The “cold sealing adhesive” indicates an adhesive which can bond members only by pressurizing.
- As the adhesion lowering component included in the adhesive, any material which can lower the bonding strength of the
adhesive layer 4 of the sealingsheet 5 and theaccommodation body 2 or the bonding strength of theadhesive layer 4 of the sealing sheet and thesubstrate 3 of the sealingsheet 5 may be used. - For example, resin used as molding lubricant such as silicon resin or fluorine-contained resin, acrylic acid resin, or striated polyester resin is preferable.
- Pulverized powder used as a filler such as silicon oxide, magnesium silicate, titanium oxide, zinc white, calcium carbonate, alumina, or talc is also preferable.
- The composition ratio of the adhesive component of the adhesive and the adhesion lowering component is determined according to the result of an bonding strength test, an extrusion test and a peeling test which will be explained later.
- B. Case that Bonding Strength is Adjusted by a Coating Method of Adhesive on the Substrate of the Sealing Sheet
- In this case, a desirable bonding strength can be obtained by coating an adhesive on the
substrate 3 of the sealingsheet 5 entirely or partially or by adjusting the coating amount of an adhesive per unit area on thesubstrate 3 of the sealingsheet 5. - When the adhesive is partially coated, it may be coated like a mesh or lines on the surface facing to the
accommodation body 2 of the sealingsheet 5 only if the solid materials T, . . . T can be completely sealed in eachstorage recess 2 a of theaccommodation body 2 respectively, or such a coating method may be combined. - When the coating amount per unit area on the
substrate 3 of the sealingsheet 5 is adjusted, a thinner may be mixed in the adhesive or the layer thickness per unit area of the adhesive coated on thesubstrate 3 of the sealingsheet 5 may be adjusted. - When the bonding strength is adjusted by a coating method of the adhesive on the
substrate 3 of the sealingsheet 5, adhesive lowering component may be contained or not contained in the adhesive. - Next, the present invention will be explained exemplifying concrete experimental results.
- (Experiment 1)
- (Manufacturing of a Sealing Sheet and a Sample for a Bonding Strength Test of a Sealing Sheet and a Sheet like Portion of an Accommodation Body)
- Heat sealing agent for polyvinyl chloride (Leader Co., Ltd., brand name: LD830G) of which main ingredient was copolymer of vinyl chloride and vinyl acetate was used as an adhesive component. Acrylic resin (Konishi Co., Ltd., brand name: KV610) which was an adhesive lowering component was mixed and plural samples of an adhesive agent solution of which heat sealing strength (bonding strength) was adjusted by varying its component ratio were prepared. The samples were coated on the surface of an aluminum foil (hard foil) (the
substrate 3 of the sealing sheet 5) with 20 μm thickness by means of a bar coater #12. - Then the aluminium foils (the
substrate 3 of the sealing sheet 5) were dried by a heat dryer at 200° C. for 20 seconds andplural sealing sheets 5 havingadhesive layers 4 with several bonding strengths were manufactured. - Such
manufactured sealing sheets 5 were thermally sealed with polyvinyl chloride sheet (Sumitomo Bakelite Co., Ltd., brand name: VSS1202) as theaccommodation body 2 by means of a heat sealer (Yasuda Seiki Co., Ltd., lever type heat sealer) having a flat plate as a heat seal bar at 150° C.×3 Kg pressure/c m2×1 second. - (Bonding Strength Test of a Sealing Sheet and a Sheet like Portion of an Accommodation Body)
- The above-mentioned thermoformed sheets were cut into 15 mm width and the cut pieces were used as samples for measuring bonding strength.
- Bonding strength test was executed by measuring peeling strength by means of Instoron type tensile strength measuring device (Shimadzu Corporation, type : AGS-100-D).
- T peeling test was executed at 200 mm/min. peeling speed according to JIS K6845.
- (Manufacturing of an Evaluation Sample for an Extrusion Test and a Peeling Test)
- Plural press-through packs1 were manufactured by heat sealing each sealing
sheet 5 having the above-mentionedadhesive layer 4 on the aluminum foil (thesubstrate 3 of the sealing sheet 5) and theaccommodation body 2 by means of a PTP filling machine (CKD Corporation, type : M-1). - Polyvinyl chloride sheet (Sumitomo Bakelite Co., Ltd., brand name: VSS1202) was used for the
accommodation body 2, No. 4 capsule as a solid substrate T was contained in eachstorage recess 2 a made by thermoforming, and theaccommodation body 2 was heat sealed at 190° C., thereby evaluation samples were manufactured for an extrusion test and a peeling test. The sheet withoutstorage recesses 2 a was cut into 15 mm width for which a bonding strength test of the sealing sheet and the sheet like portion of the accommodation body was executed. - (Extrusion Test)
- For each press-through pack1 manufactured as mentioned above, the No. 4 capsule contained in each
storage recess 2 a was obtained by breaking thesealing sheet 5 by pushing (by fingers) the contained capsule from the projectingportion 2 c (polyvinyl chloride sheet side) as outer surface of the storage recess of theaccommodation body 2 into the direction of the sealingsheet 5. Peeling and floating were observed for the adhesion areas R2 of theadhesive layer 4 of the sealingsheet 5 and the sheet likeportions 2 b, . . . 2 b of theaccommodation body 2 except for the areas R1 sealing thestorage recess 2 a from which the No. 4 capsules were obtained. - When peeling and floating of the sealing
sheet 5 weren't observed at the areas R2, it was evaluated as good (◯). When peeling and floating were partially observed at the areas R2 other than the areas R1 corresponding tostorage recesses 2 a from which the No. 4 capsules were obtained, it was evaluated as not so good (Δ). When peeling and floating were widely observed at the areas R2 other than the areas R1 corresponding tostorage recesses 2 a from which the No. 4 capsules were obtained, it was evaluated as not good (X). - (Peeling Test)
- The same samples of the press-through pack1 as the samples used for the extrusion test were used and rupture of the sealing
sheet 5 was observed when the sealingsheet 5 was peeled off the accommodation body 2 (polyvinyl chloride sheet). - When the sealing
sheet 5 was easily peeled off the accommodation body 2 (polyvinyl chloride sheet) without being ruptured or cut, it was evaluated as good (◯). When the sealingsheet 5 was easily peeled off the accommodation body 2 (polyvinyl chloride sheet) however the sealingsheet 5 was cut or ruptured, it was evaluated as not so good (Δ). When the sealingsheet 5 was difficult to be peeled off the accommodation body 2 (polyvinyl chloride sheet) and was cut or ruptured when it was forcibly peeled off the accommodation body 2 (polyvinyl chloride sheet), it was evaluated as not good (X). - The result is shown in the following table 1.
TABLE 1 Component quantity main ingredient 4 mg Lactose appropriate amount Starch 40 mg polyvinyl alcohol 4 mg magnesium stearate 1 mg total weight 130 mg - According to the table 1, it was understood that the preferable bonding strength of the
accommodation body 2 and thesealing sheet 5 was from 0.9N/15 mm width to 3.1N/15 mm width. - Further, it became apparent that the bonding strength of the sealing
sheet 5 and the sheet likeportion 2 b of theaccommodation body 2 was preferably adjusted from 1.3N/15 mm width to 2.7N/15 mm width by repeating similar tests. - The compensated value in the table 1 indicates a value on the regression line obtained by analyzing the actual measurement and is a value compensated by the following equation.
- N=−0.0871X+9.1695(N: compensated value)
- R 2=0.9965(R: confidence limit)X=weight % of KV610
- (Experiment 2)
- (Manufacturing of a Sealing Sheet and a Press-Through Pack)
- Heat sealing agent for polyvinyl chloride (Leader Co., Ltd. Brand name: LD830G) of which main ingredient was copolymer of vinyl chloride and vinyl acetate was used as an adhesive component. Acrylic resin (Konishi Co., Ltd., brand name: KV610) which was an adhesive lowering component was mixed and plural samples of an adhesive agent solution of which heat sealing strength (bonding strength) was adjusted by varying its component ratio were prepared. The samples were coated on the surface of an aluminum foil (hard foil) with 20 μm thickness (the
substrate 3 of the sealing sheet 5) by means of a bar coater #12. - Then the foils (the
substrate 3 of the sealing sheet) were dried by a heat dryer at 200° C. for 20 seconds andplural sealing sheets 5 havingadhesive layers 4 with several bonding strengths were manufactured. - Plural storage recesses2 a are thermally formed in lines for containing tablets having concave plain and 7 mm diameter (hereinafter called 7 mm diameter tablet) by a junior blister packing machine from polyvinyl chloride sheet (Sumitomo Bakelite Co., Ltd., brand name: VSS1105SF). The 7 mm diameter tablet was contained in each
storage recess 2 a formed as mentioned above. Theaccommodation body 2 andplural sealing sheets 5 havingadhesive layers 4 of several bonding strength on thesubstrates 3 were thermally bonded at 130° C. by means of semi-automatic PTP packing machine (Daiwa Kasei Kogyo Co., Ltd, Type:K-200KS), thereby plural press-through packs 1 containing 7 mm diameter tablets were manufactured. - (Extrusion Test)
- For each press-through pack1 manufactured as mentioned above, the 7 mm diameter tablet contained in each
storage recess 2 a was obtained by breaking thesealing sheet 5 by pushing (by fingers) the contained tablet from the projectingportion 2 c (polyvinyl chloride sheet side) as outer surface of the storage recess of theaccommodation body 2 into the direction of the sealingsheet 5. Peeling and floating were observed for the adhesion areas R2 of theadhesive layer 4 of the sealingsheet 5 and the sheet likeportions 2 b, . . . 2 b of theaccommodation body 2 except for the areas R1 sealing the storage recesses 2 a from which the 7 mm diameter tablets were obtained. - When peeling and floating of the sealing sheet5 (aluminum foil) weren't observed at the areas R2, it was evaluated as good (◯). When peeling and floating were partially observed at the areas R2 other than the areas R1 corresponding to
storage recesses 2 a from which the 7 mm diameter tablets were obtained, it was evaluated as not so good (Δ). When peeling and floating the sealing sheet were widely observed at the areas R2 other than the areas R1 corresponding tostorage recesses 2 a from which the 7 mm diameter tablets were obtained, it was evaluated as not good (X). - (Peeling Test)
- The same samples of the press-through pack1 as the samples used for an extrusion test were used and rupture of the sealing
sheet 5 was observed when the sealingsheet 5 was peeled off the accommodation body 2 (polyvinyl chloride sheet). - When the sealing
sheet 5 was easily peeled off the accommodation body 2 (polyvinyl chloride sheet) without being ruptured or cut, it was evaluated as good (◯). When the sealingsheet 5 was easily peeled off the accommodation body 2 (polyvinyl chloride sheet) however it was cut or ruptured, it was evaluated as not so good (Δ). When the sealingsheet 5 was difficult to be peeled off the accommodation body 2 (polyvinyl chloride sheet) and was cut or ruptured when it was forcibly peeled off the accommodation body 2 (polyvinyl chloride sheet), it was evaluated as not good (X). - (Bonding Strength Test of a Sealing Sheet and a Sheet like Portion of an Accommodation Body)
- The bonding part R2 (where the storage recesses 2 a of the
accommodation body 2 aren't provided) of the sheet likeportions 2 b of theaccommodation body 2 and thesealing sheet 5 of each press-through pack 1 manufactured as mentioned above was cut into 15 mm width and the cut pieces were used as samples for measuring bonding strength. - The bonding strength test was executed by measuring peeling strength by means of a strograph (TOYO SEIKI Co., Ltd., type M1).
- T peeling test was executed according to JIS K6845 at a peeling speed of 100 mm/min.
- The result is shown in the following table 2.
TABLE 2 bonding strength (N/15 mm width) (peeling speed: extrusion 100 mm/min.) (7 mm Component ratio actual compensated diameter peel- of adhesive measurement value tablet) ing LD830G/KV610 = 50/50 9.6 9.3 ∘ x LD830G/KV610 = 40/60 8.8 8.1 ∘ x LD830G/KV610 = 35/65 7.4 7.6 ∘ x LD830G/KV610 = 30/70 6.1 7.0 ∘ Δ LD830G/KV610 = 25/75 5.8 6.5 ∘ ∘ LD830G/KV610 = 20/80 5.7 5.9 ∘ ∘ LD830G/KV610 = 10/90 5.1 4.8 ∘ ∘ LD830G/KV610 = 5/95 4.7 4.2 Δ ∘ LD830G/KV610 = 3/97 4.1 4.0 x ∘ - From the table 2, it was understood that the preferable bonding strength of the
accommodation body 2 and thesealing sheet 5 was from 4.2N/15 mm width to 7.0N/15 mm width. - Further, it became apparent that the bonding strength of the sealing
sheet 5 and the sheet likeportion 2 b of theaccommodation body 2 was preferably adjusted from 4.8N/15 mm width to 6.5N/15 mm width by repeating similar tests. - The compensated value in the table 2 indicates a value on the regression line obtained by analyzing the actual measurement and is a value compensated by the following equation.
- N=−0.1123X+14.882(N: compensated value)
- R 2=0.8968(R: confidence limit)X=weight % of KV610
- When aluminum foil is used for the
substrate 3 of the sealingsheet 5, a print layer may be provided for showing company name, brand name, brand code and so on at the surface provided with theadhesive layer 4 or its opposite surface. Further, a surface protection layer made of nitrocellulose, acrylic resin, epoxy resin, melamine resin or a mixed resin of at least two of them may be provided on the printing surface opposite to the surface with theadhesive layer 4 in order to prevent spots such as fingerprint and erosion, or to polish. - If necessary, V-shaped grooves or perforations may be provided for the sheet like
portions 2 b, . . . 2 b of theaccommodation body 2 for separating per eachstorage recess 2 a, . . . 2 a. - (Dividing Test of Dividable Tablet)
- Granule including lactose—starch as additives was tabletted at various tabletting pressures and several kinds of dividable tablets having a dividable line, with 7 mm diameter and 130 mg total weight were manufactured.
TABLE 3 bonding strength (N/15 mm width) (peeling speed: 200 mm/min.) extrusion component ratio actual compensated (No. 4 peel- of adhesive measurement Value capsule) ing LD830G/KV610 = 50/50 4.9 4.8 ∘ x LD830G/KV610 = 40/60 3.9 3.9 ∘ x LD830G/KV610 = 35/65 3.4 3.5 ∘ x LD830G/KV610 = 30/70 3.0 3.1 ∘ Δ LD830G/KV610 = 25/75 2.7 2.6 ∘ ∘ LD830G/KV610 = 20/80 2.1 2.2 ∘ ∘ LD830G/KV610 = 10/90 1.3 1.3 ∘ ∘ LD830G/KV610 = 5/95 1.0 0.9 Δ ∘ LD830G/KV610 = 3/97 0.8 0.7 x ∘ - Then the press-through
pack 1A as mentioned above was similarly manufactured but thus prepared several kinds of tablets were used instead of the No. 4 capsule or the 7 mm diameter tablet. - The press-through
pack 1A containing dividable tablets Td, . . . Td with a dividing line L in the storage recesses 2 a, . . . 2 a of theaccommodation body 2 was placed on the flat plate 21S on a table 21 as shown in FIG. 2(a). Aplastic plate 22 of about the same size as the press-throughpack 1A was pressed above the press-throughpack 1A so that theaccommodation body 2 of the press-throughpack 1A was pushed into the direction of the sealing sheet 5 (see FIG. 2(b)). Then the dividable tablets Td, . . . Td contained in the storage recesses 2 a, . . . 2 a of theaccommodation body 2 were divided. The divided condition thereof were observed (see FIG. 2(c)). - As the result, the dividable tablets Td, . . . Td of the shapes shown in FIG. 3-FIG. 6 contained in each
storage recess 2 a, . . . 2 a, and divided at a pressure in the direction of the thickness of tablet of not more than 50N, more specifically from 15N to 40N were all divided into two in eachstorage recess 2 a, . . . 2 a. - The shapes of the dividable tablets will be explained in more detail. The dividable tablet Td1 in FIG. 3 has a V-shaped dividing line L at a center of one surface Sa thereof. The surface Sa of the tablet Td1 provided with the dividing line L is formed concave so that the deepest portion accords with the position of the dividing line L and a corner D1 of the concave surface and a side Sc of the tablet is rounded. Further, a surface Sb opposite to the surface Sa of the tablet Td1 having the dividing line L is formed convex of which highest portion accords with the most deepest portion of the dividing line L.
- When pressure is applied on the dividable tablet Td1, ripping force is concentrated on the dividing line L by cooperation of the concave surface Sa and the convex surface Sb so that the dividable tablet Td1 can be easily divided along the dividable line L.
- The dividable tablet Td2 in FIG. 4 is provided with an annular part C with a fixed space from its circumference for a design purpose on the surface Sb opposite to the surface Sa having a dividing line L and also provided with a convex surface inside of the annular part C. Its construction is actually similar to the construction of the dividable tablet Td1 and their effects are the same.
- The dividable tablet Td3 in FIG. 5 is provided with a V-shaped dividing line L of which deepest portion is deeper than a corner D2 of a surface Sa and a side Sc of the tablet Td3. The surface Sa with the dividing line L is flat, the corner D2 is rounded, and convex surface is formed at a surface Sb opposite to the surface Sa.
- When pressure is applied on the dividable tablet Td3, ripping force is concentrated on the dividing line L because of the convex shape of the surface Sb and the dividing line L is formed V-shaped, thereby the tablet Td3 can be easily divided along the dividing line L.
- The dividable tablet Td4 shown in FIG. 6 has a V-shaped dividing line L at a center of one surface Sa thereof and the surface Sa is designed such that V-shaped form which is gentle comparing to the dividing line L is continued from the dividing line L to the side Sc of the tablet Td4 so that the deepest part thereof accords with the position of the dividing line L. A corner D3 of the V-shaped surface and the side Sc is rounded and a surface Sb opposite to the surface Sa is gently V-shaped having the deepest portion thereof at the center. The deepest portion of the V-shaped surface Sb is designed to be aligned with the dividing line L of the surface Sa and a corner D4 of the gently V-shaped surface Sb and the side Sc of the tablet is rounded.
- When pressure is applied on the dividable tablet Td4, the tablet Td4 can be easily divided because pressure applied on the gently V-shaped surface Sa is concentrated on the dividing line L and the deepest part of the V-shaped surface Sb accords with the deepest part of the V-shaped dividing line L.
- As shown in FIG. 2(d), the sealing
sheet 5 was peeled off theaccommodation body 2 of the press-throughpack 1A containing divided tablets Tdh, . . . Tdh in the storage recesses 2 a, . . . 2 a, thesheet 5 could be peeled off without being ruptured and all the divided tablet Tdh, . . . Tdh could be obtained. - When the dividable tablets Td, . . . Td contained in the storage recesses2 a, . . . 2 a were pushed into the sealing
sheet 5 direction from the accommodation body 2 (polyvinyl chloride sheet) and taken out one by one by breaking thesealing sheet 5, it was observed whether peeling or floating was occurred at the areas R2 other than the areas R1 of theaccommodation body 2 from where the dividable tablets Td were taken out. The press-throughpack 1A containing dividable tablets Td1, Td2, Td3, Td4 in eachstorage recess 2 a, . . . 2 a didn't cause peeling or floating at the areas R2 and the dividable tablets Td1, Td2, Td3, Td4 were taken out of the press-throughpack 1A without divided respectively. - Each press-through
pack 1A containing the dividable tablets Td1, Td2, Td3, Td4 was packed in a box (10 tablets PTP×100 sheets) and transported by a regular delivery method. In such a test, any of the dividable tablets Td1, Td2, Td3, Td4 contained in eachstorage recess 2 a, . . . 2 a of the press-throughpack 1A weren't divided or dropped outside by breaking thesealing sheet 5. - At least one dividable tablet Td may be contained in each
storage recess 2 a, . . . 2 a of theaccommodation body 2 of the press-throughpack 1A. The dividable tablet Td may be positioned in therecess 2 a while the surface Sa with a dividing line L faces theaccommodation body 2 or the surface Sb faces theaccommodation body 2. Further, the surfaces Sa of some tablets Td may face theaccommodation body 2 and the surfaces Sb of the others face theaccommodation body 2. - The tablets Td1, Td2, Td3, Td4 are only a sample of dividable tablets contained in the
storage recess 2 a, . . . 2 a of theaccommodation body 2. Any types of dividable tablets may be used only if the tablets Td can be divided along the dividing line L when pressure is applied on the surface Sa having the dividing line L or on the surface Sb opposite to the surface Sa and the force is concentrated on the line L. - It is preferable that a concave or a convex is formed on at least one surface Sa having a dividing line L of the tablet Td or its opposite surface Sb so that the tablets can be easily divided along the dividing line L.
- Such a dividable tablet may be a naked tablet (uncoated tablet) or a coated tablet wherein coating material such as sugarcoating or film coating is appropriately applied on the naked tablet.
- The diameter of a dividable tablet is preferably from 3 mm to 30 mm and more preferably from 5 mm to 12 mm considering practical prescription such as patient compliance.
- Industrial Applicability
- According to the press-through pack of the present invention, solid materials can be obtained one by one by breaking the part of the sheet sealing the storage recess without causing floating or peeling at the adhesion area of the sheet like portion of the accommodation body and the adhesive layer of the sealing sheet when the projecting portions as outer surface of the storage recess containing solid materials are pushed in the direction of the sealing sheet by fingers. Further, when the sealing sheet was peeled off the accommodation body, plural or whole solid materials contained in the press-through pack can easily be obtained at one time because the sealing sheet is bonded to the accommodation body so as to be easily peeled off without being broken.
- The accommodation body and the sealing sheet can be easily separated after all the solid materials are obtained so that disposal treatment and recycle are easily accomplished by disposing them separately.
- Further according to the present invention, when dividable tablets are contained in the storage recesses, they can be obtained one by one and also a large amount of tablets can be divided at one time and the divided tablets can be easily obtained at one time.
- When the press-through pack of the present invention is used, solid materials can be obtained by pushing the projecting portions as outer surface of the storage recesses containing solid materials and breaking the part of the sheet sealing the storage recesses. And also when the sealing sheet is peeled off, it can be easily separated from the accommodation body without being broken.
- The press-through pack of the present invention has such an excellent effect so that it can be preferably used for individually packing materials such as solid medicine like a tablet or a capsule, confections like a candy, and solid materials like health food, fishing baits or toys.
- The sealing sheet for the press-through pack of the present invention is preferably used for manufacturing individual packing form of such solid materials.
- Further according to the taking-out method of the present invention, a dividable tablet can be obtained from the press-through pack one by one and also a large amount of dividable tablet can be divided in the press-through pack and obtained at one time.
Claims (10)
1. A press-through pack comprising;
an accommodation body (2) having plural storage recesses (2 a) provided with sheet like portions (2 b) therebetween, and
a sealing sheet (5) having a substrate (3) on which one surface side an adhesive layer (4) is formed, said accomodation body (2) being sealed tightly by said sealing sheet (5) in a manner that said adhesive layer (4) and said sheet like portions (2 b) are bonded to each other, with a solid material (T) contained in each of said plural storage recesses (2 a) wherein,
said sealing sheet (5) is made of such material that the part of said sealing sheet (5) responding to said recess (2 a), a part in which a solid material (T) in contained, is partly ruptured without causing floating and peeling of adhesion portion between said adhesive layer (4) of said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (3) when pushing the projecting portion of the outer side of said recess (2 a) with fingers, whereby said solid material (T) contained in said recess (2 a) is taken out and wherein,
said sealing sheet (5) is further bonded to said sheet like portions (2 b) of said accommodation body (2) in a manner that said sealing sheet (5) is easily peeled off from said accommodation body (2).
2. The press-through pack as set forth in claim 1 , wherein said solid material (T) is a dividable tablet.
3. The press-through pack as set forth in claim 1 or 2, wherein the bonding strength between said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (2) is not less than 0.9N/15 mm width and not more than 3.1N/15 mm width in T peeling test executed at a peeling speed of 200 mm/min.
4. The press-through pack as set forth in claim 1 or 2, wherein the bonding strength between said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (2) is not less than 4.2N/15 mm width and not more than 7.0N/15 mm width in T peeling test executed at a peeling speed of 100 mm/min.
5. The press-through pack as-set forth in one of claims 1 to 4 , wherein an adhesion lowering component is mixed for an adhesive component of an adhesive forming said adhesive layer (4).
6. The press-through pack as set forth in one of claims 1 to 5 , wherein said adhesive layer (4) is coated on one surface side of said sealing sheet (5) by a partial coating method.
7. A sealing sheet (5) for a press-through pack in which a substrate (3) and an adhesive layer (4) formed on one surface of said substrate (3) are provided, said adhesive layer (4) being bonded to sheet like portions (2 b) of an accommodation body (2) having plural storage recesses (2 a) provided with sheet like portions (2 b) therebetween, for tightly sealing the accommodation body (2) wherein,
said sealing sheet (5) is made of such material that the part of said sealing sheet (5) responding to said recess (2 a), a part in which a solid material (T) is contained, is partly ruptured without causing floating and peeling of adhesion portion between said adhesive layer (4) of said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (2) when pushing the projecting portion of the outer side of said recess (2 a) with fingers, whereby said solid material (T) contained in said recess (2 a) is taken out and wherein,
said sealing sheet (5) is designed to be bonded to said sheet like portions (2 b) of said accommodation body (2) in a manner that said sealing sheet (5) is easily peeled off from said accommodation body (2).
8. The sealing sheet for the press-through pack as set forth in claim 7 , wherein the bonding strength between said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (2) is adjusted not less than 0.9N/15 mm width and not more than 3.1N/15 mm width in T peeling test executed at a peeling speed of 200 mm/min.
9. The sealing sheet for the press-through pack as set forth in claim 7 , wherein the bonding strength between said sealing sheet (5) and said sheet like portion (2 b) of said accommodation body (2) is adjusted not less than 4.2N/15 mm width and not more than 7.0N/15 mm width in T peeling test executed at a peeling speed of 100 mm/min.
10. A taking-out method of tablets from a press-through pack wherein,
said press-through pack (1) of claim 2 is placed on a flat plate,
all dividable tablets (T) contained in each storage recess (2 a) of said accommodation body (2) of said press-throught pack (1) are divided by applying an equal force from upward of said press-through pack (1) placed on the plate by means of a flat plate, and
said sealing sheet (5) is peeled off said accommodation body (2) and all the divided tablets contained in each storage recess (2 a) of said accommodation body (2) are obtained at one time.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/663,690 US20040060845A1 (en) | 1997-10-02 | 2003-09-17 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9-269845 | 1997-10-02 | ||
JP26984597 | 1997-10-02 | ||
PCT/JP1998/004452 WO1999018008A1 (en) | 1997-10-02 | 1998-10-01 | Press-through pack, seal sheet for press-through pack and method of preparing tablets |
US09/539,701 US6637596B1 (en) | 1997-10-02 | 2000-03-31 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
US10/663,690 US20040060845A1 (en) | 1997-10-02 | 2003-09-17 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US09/539,701 Division US6637596B1 (en) | 1997-10-02 | 2000-03-31 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
Publications (1)
Publication Number | Publication Date |
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US20040060845A1 true US20040060845A1 (en) | 2004-04-01 |
Family
ID=17477998
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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US09/539,701 Expired - Fee Related US6637596B1 (en) | 1997-10-02 | 2000-03-31 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
US10/663,690 Abandoned US20040060845A1 (en) | 1997-10-02 | 2003-09-17 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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US09/539,701 Expired - Fee Related US6637596B1 (en) | 1997-10-02 | 2000-03-31 | Press-through pack, sealing sheet for press-through pack, and preparation method of tablet |
Country Status (11)
Country | Link |
---|---|
US (2) | US6637596B1 (en) |
EP (1) | EP1057743B1 (en) |
JP (1) | JP4118509B2 (en) |
AT (1) | ATE314282T1 (en) |
AU (1) | AU735136B2 (en) |
CA (1) | CA2306351C (en) |
CY (1) | CY1105588T1 (en) |
DE (1) | DE69833041T2 (en) |
DK (1) | DK1057743T3 (en) |
ES (1) | ES2255734T3 (en) |
WO (1) | WO1999018008A1 (en) |
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WO2012049447A1 (en) * | 2010-10-15 | 2012-04-19 | Future Technology (Uk) Ltd | Dispensing containers |
US20180162618A1 (en) * | 2015-08-04 | 2018-06-14 | Ckd Corporation | Blister sheet and blister packaging machine |
US20230121451A1 (en) * | 2020-06-05 | 2023-04-20 | The Spice House LLC | Granular Food Items Packaging System |
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JP3839065B2 (en) | 1998-04-03 | 2006-11-01 | 協和醗酵工業株式会社 | Split tablets and press-through packs |
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AU2002339125A1 (en) * | 2002-11-11 | 2004-06-03 | Wright, Fenn And Co. Ltd. | Blister pack |
TW200502000A (en) * | 2003-03-28 | 2005-01-16 | Kyowa Hakko Kogyo Kk | Dividing tablet |
WO2005056419A1 (en) * | 2003-12-10 | 2005-06-23 | 3Point Blue Limited | Improvements in or relating to blister packs |
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WO2009042541A1 (en) * | 2007-09-26 | 2009-04-02 | Pioneer Hi-Bred International, Inc. | Apparatus and method to package articles for storage and identification |
TWI453150B (en) * | 2007-10-29 | 2014-09-21 | Toyo Aluminium Kk | Press-through package |
US10420704B2 (en) * | 2013-06-13 | 2019-09-24 | Nipro Corporation | PTP sheet for pharmaceutical packaging |
JP7249666B2 (en) | 2020-10-30 | 2023-03-31 | 株式会社リガク | X-ray fluorescence analyzer |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2386416A (en) * | 1943-03-01 | 1945-10-09 | Warren F Wilhelm | Tablet and means for packaging same |
US3924748A (en) * | 1974-04-11 | 1975-12-09 | Milton Braverman | Closure for multicompartment medicinal dispensing device |
US3924746A (en) * | 1972-07-12 | 1975-12-09 | Paco Packaging | Childproof package |
US4158411A (en) * | 1976-05-10 | 1979-06-19 | Hall Douglas C | Dispensing package |
US5172812A (en) * | 1992-01-23 | 1992-12-22 | Rexham Corporation | Child-resistant paperboard blister package and method of making the same |
US5318824A (en) * | 1986-05-02 | 1994-06-07 | Mitsui Petrochemical Industries, Ltd. | Packaging structure |
US5360116A (en) * | 1991-11-18 | 1994-11-01 | Alusuisse-Lonza Services Ltd. | Blister pack with a tear-off aid |
US5486390A (en) * | 1994-04-25 | 1996-01-23 | Mobil Oil Corporation | Recyclable blister package |
US5624036A (en) * | 1994-12-08 | 1997-04-29 | Alusuisse Technology & Management Ltd. | Blister pack |
US5785180A (en) * | 1995-06-22 | 1998-07-28 | G. D. Searle & Co. | Child-resistant package |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS523817A (en) * | 1975-06-24 | 1977-01-12 | Kyuichi Yano | Device for recovering tablets, etc. |
DE3532257A1 (en) * | 1985-09-10 | 1987-03-12 | Liedtke Pharmed Gmbh | Medicament blister pack with integrated tablet breaking strip |
JPH0423255Y2 (en) * | 1987-05-14 | 1992-05-29 | ||
US5232702A (en) * | 1991-07-22 | 1993-08-03 | Dow Corning Corporation | Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices |
KR100235089B1 (en) * | 1992-05-14 | 1999-12-15 | Mitsui Chemicals Inc | Ptp or blister packaging articles and packaging material therefor |
JP3868508B2 (en) * | 1993-01-29 | 2007-01-17 | 日本ゼオン株式会社 | Press-through package |
JP3605430B2 (en) * | 1995-01-12 | 2004-12-22 | 大日本印刷株式会社 | Lid material having press-through function and package using the same |
JP3670710B2 (en) * | 1995-04-04 | 2005-07-13 | 協和醗酵工業株式会社 | Tablet with split groove and ridge with split groove forming convex part |
JP3880093B2 (en) * | 1995-08-08 | 2007-02-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | tablet |
JP3553220B2 (en) * | 1995-08-17 | 2004-08-11 | ダイセル化学工業株式会社 | Sealable film and method for producing the same |
-
1998
- 1998-10-01 AT AT98945580T patent/ATE314282T1/en not_active IP Right Cessation
- 1998-10-01 JP JP2000514833A patent/JP4118509B2/en not_active Expired - Fee Related
- 1998-10-01 EP EP98945580A patent/EP1057743B1/en not_active Expired - Lifetime
- 1998-10-01 AU AU92822/98A patent/AU735136B2/en not_active Ceased
- 1998-10-01 CA CA002306351A patent/CA2306351C/en not_active Expired - Fee Related
- 1998-10-01 WO PCT/JP1998/004452 patent/WO1999018008A1/en active IP Right Grant
- 1998-10-01 ES ES98945580T patent/ES2255734T3/en not_active Expired - Lifetime
- 1998-10-01 DK DK98945580T patent/DK1057743T3/en active
- 1998-10-01 DE DE69833041T patent/DE69833041T2/en not_active Expired - Lifetime
-
2000
- 2000-03-31 US US09/539,701 patent/US6637596B1/en not_active Expired - Fee Related
-
2003
- 2003-09-17 US US10/663,690 patent/US20040060845A1/en not_active Abandoned
-
2006
- 2006-02-08 CY CY20061100172T patent/CY1105588T1/en unknown
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2386416A (en) * | 1943-03-01 | 1945-10-09 | Warren F Wilhelm | Tablet and means for packaging same |
US3924746A (en) * | 1972-07-12 | 1975-12-09 | Paco Packaging | Childproof package |
US3924748A (en) * | 1974-04-11 | 1975-12-09 | Milton Braverman | Closure for multicompartment medicinal dispensing device |
US4158411A (en) * | 1976-05-10 | 1979-06-19 | Hall Douglas C | Dispensing package |
US5318824A (en) * | 1986-05-02 | 1994-06-07 | Mitsui Petrochemical Industries, Ltd. | Packaging structure |
US5360116A (en) * | 1991-11-18 | 1994-11-01 | Alusuisse-Lonza Services Ltd. | Blister pack with a tear-off aid |
US5172812A (en) * | 1992-01-23 | 1992-12-22 | Rexham Corporation | Child-resistant paperboard blister package and method of making the same |
US5486390A (en) * | 1994-04-25 | 1996-01-23 | Mobil Oil Corporation | Recyclable blister package |
US5624036A (en) * | 1994-12-08 | 1997-04-29 | Alusuisse Technology & Management Ltd. | Blister pack |
US5785180A (en) * | 1995-06-22 | 1998-07-28 | G. D. Searle & Co. | Child-resistant package |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012049447A1 (en) * | 2010-10-15 | 2012-04-19 | Future Technology (Uk) Ltd | Dispensing containers |
CN103391888A (en) * | 2010-10-15 | 2013-11-13 | 未来技术(英国)有限公司 | Dispensing containers |
US8740003B2 (en) | 2010-10-15 | 2014-06-03 | Future Technology (Uk) Ltd | Dispensing containers |
US20180162618A1 (en) * | 2015-08-04 | 2018-06-14 | Ckd Corporation | Blister sheet and blister packaging machine |
US10589914B2 (en) * | 2015-08-04 | 2020-03-17 | Ckd Corporation | Blister sheet and blister packaging machine |
US20230121451A1 (en) * | 2020-06-05 | 2023-04-20 | The Spice House LLC | Granular Food Items Packaging System |
Also Published As
Publication number | Publication date |
---|---|
CA2306351A1 (en) | 1999-04-15 |
ES2255734T3 (en) | 2006-07-01 |
AU9282298A (en) | 1999-04-27 |
EP1057743A4 (en) | 2003-03-12 |
AU735136B2 (en) | 2001-06-28 |
JP4118509B2 (en) | 2008-07-16 |
ATE314282T1 (en) | 2006-01-15 |
CA2306351C (en) | 2007-06-12 |
DK1057743T3 (en) | 2006-03-06 |
DE69833041T2 (en) | 2006-07-06 |
EP1057743B1 (en) | 2005-12-28 |
DE69833041D1 (en) | 2006-02-02 |
CY1105588T1 (en) | 2010-07-28 |
EP1057743A1 (en) | 2000-12-06 |
US6637596B1 (en) | 2003-10-28 |
WO1999018008A1 (en) | 1999-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |