US20040130677A1 - Apparatus and method for measuring vision defects of a human eye - Google Patents

Apparatus and method for measuring vision defects of a human eye Download PDF

Info

Publication number
US20040130677A1
US20040130677A1 US10/625,189 US62518903A US2004130677A1 US 20040130677 A1 US20040130677 A1 US 20040130677A1 US 62518903 A US62518903 A US 62518903A US 2004130677 A1 US2004130677 A1 US 2004130677A1
Authority
US
United States
Prior art keywords
wavefront
eye
apparatus recited
optical beam
retina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/625,189
Inventor
Junzhong Liang
James Burkhalter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon RefractiveHorizons LLC
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/665,748 external-priority patent/US6270221B1/en
Application filed by Alcon Inc filed Critical Alcon Inc
Priority to US10/625,189 priority Critical patent/US20040130677A1/en
Publication of US20040130677A1 publication Critical patent/US20040130677A1/en
Assigned to ALCON, INC. reassignment ALCON, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ALCON UNIVERSAL, LTD.
Assigned to ALCON REFRACTIVEHORIZONS, INC. reassignment ALCON REFRACTIVEHORIZONS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ALCON, INC.
Abandoned legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1015Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for wavefront analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J9/00Measuring optical phase difference; Determining degree of coherence; Measuring optical wavelength

Definitions

  • the invention relates generally to optical aberration measurement and correction, and in particular to projection techniques in the objective measurement and correction of the human eye using a wavefront sensor.
  • Penny '791 discloses the use of autorefractometer measurements for determining the appropriate corneal surface reshaping to provide emmetropia, a condition of a normal eye when parallel rays are focused exactly on the retina and vision is optimum.
  • Spatially resolved refraction data in combination with measured existing surface contour of the anterior surface of the eye, enable a calculation of a detailed spatially resolved new contour that provides corrected vision.
  • Liang et al. disclose the use of a Hartmann-Shack wavefront sensor to measure ocular aberrations by measuring the wavefront emerging from the eye by retinal reflection of a focused laser light spot on the retina's fovea.
  • a parallel beam of laser light passes through beam splitters and a lens pair that brings the beam to a focus point on the retina by the optics of the eye.
  • Possible myopia or hyperopia of the tested eye is corrected by movement of a lens within the lens pair.
  • the focused light on the fovea is then assumed to be diffusely reflected and acts as a point source located on the retina.
  • the reflected light passes through the eye and forms a distorted wavefront in front of the eye that results from the ocular aberrations.
  • the aberrated wavefront is then directed to the wavefront sensor.
  • a point source of radiation on the retina would be ideal for such measurements.
  • the perfect eye receives a collimated beam of light
  • the best possible image on the retina is a diffraction-limited spot.
  • collimated parallel beams are used with the optics of the eye being measured to achieve this diffraction-limited spot for such objective measurements. To do so requires that a setup for each patient include a corrective lens or lens combination and adjustments thereto for accommodating that patient's specific visual acuity.
  • the patient may be a wild or domestic animal, living or dead.
  • a method aspect of the invention for measuring optical characteristics of an optical system including the focusing of an optical beam proximate an anterior surface of the optical system, for placing a finite source of secondary radiation on a focal surface of the optical system, which secondary radiation is emitted from the focal surface as a reflected wavefront of radiation that passes through the optical system, transmitting the diffusely reflected wavefront onto a wavefront analyzer, and measuring characteristics of the optical system associated with the reflected wavefront.
  • the method includes the step of measuring defects of the eye, which includes the steps of focusing an optical beam onto an anterior surface of the eye, other than the retina, for providing a finite source of secondary radiation on the retina of the eye, which secondary source of radiation is emitted from the retina as a reflected wavefront of radiation that passes through the eye, directing the reflected wavefront onto a wavefront analyzer, and measuring distortions associated with the reflected wavefront.
  • a preferred embodiment of the invention includes the step of focusing the projected optical beam on the anterior surface of the cornea. In an alternate embodiment the optical beam is focused behind the retina.
  • An apparatus for effectively performing such measurements includes means for focusing an optical beam onto an anterior surface of the optical system or eye, other than the retina, for providing a finite secondary source of radiation source on the focal surface, or retina of the eye, which finite secondary radiation source is emitted from the retina as a reflected wavefront of radiation that passes through the eye, means for directing the reflected wavefront onto a wavefront analyzer, and a wavefront analyzer for measuring distortions associated with the reflected wavefront.
  • a laser beam is focused onto the surface of the cornea with a long-focal-length lens, which converges the beam through a small angle for passing through the iris of the eye and providing a finite secondary source of radiation source on the retina of the eye, which finite secondary radiation source is emitted from the retina through the optics of the eye as the wavefront to be measured.
  • the apparatus comprises means for focusing the optical beam behind the retina
  • FIG. 1 is a diagrammatic illustration of an apparatus for measuring visual defects of an eye, according to the present invention.
  • FIG. 2 is a diagrammatic illustration of an eye being measured by the apparatus of the present invention, with the focus on the cornea.
  • FIG. 2A is a diagrammatic illustration of an eye being measured by the apparatus of the present invention, with the focus behind the retina.
  • FIGS. 3A and 3B are diagrammatic illustrations of an ideal eye with perfect vision and an aberrated eye, respectively.
  • FIG. 4 is a diagrammatic illustration of an eye being measured with collimated light focused on the retina to a diffraction-limited spot.
  • FIG. 5 is a partial perspective view of a pinhole imaging plate and detector plane of a wavefront sensor used in a preferred embodiment of the present invention.
  • a preferred embodiment of a measurement apparatus 10 of the present invention is herein initially described with reference to the schematic diagram of FIG.1.
  • a beam 12 of optical radiation is directed into an eye 14 to be measured, so that a small area or spot 16 is formed as a secondary source of radiation in the foveal region of the retina 18 (FIG. 2).
  • the beam 12 is focused through a small angle 13 onto an anterior surface 20 of the eye 14 , other than the retina, and in a preferred embodiment of the present invention, focused on an anterior corneal surface 22 of the cornea 24 for further projection through the iris 26 and lens 28 and onto the retina 18 .
  • a projected beam 12 ′ of optical radiation is directed into an eye 14 ′ to be measured, so that a small area or measurable spot 16 ′ is formed as a secondary radiation source in the foveal region of the retina 18 ′ (FIG. 2A).
  • the beam 12 ′ is focused through a small angle 13 ′ at a point behind the eye 14 ′, after passing through the iris 26 ′, the lens 28 ′, and the retina 18 ′.
  • such a spot 36 is even larger, where most of the blurring will be due to finite aberrations found in typical eyes.
  • distorted wavefronts 38 result, as illustrated with reference to FIG. 3B. Having to deal with a series of distorted wavefronts 38 resulting from aberrations, and further dealing with a blurring of such distorted wavefronts 38 resulting from diffraction effects and the finite aberrations of the eye, results in a spot 36 source of light rather than a point 32 source, representing one of the challenges in measuring the visual defects or an eye.
  • the optical wavefronts 40 scattered from the retina 18 are transferred by a series of optical elements, which will be described in further detail in the following, to a wavefront sensor 42 , which divides each incident wavefront into a group of “wavelets,” referred to herein with numeral 50 , using an opaque plate 44 having a planar array of apertures 46 (FIG. 5). Further, the wavefront sensor 42 records the position 48 at which each wavelet 50 passing through the aperture 46 strikes a detector plane 54 such as a charged-coupled device (CCD), herein provided as one preferred embodiment, the plane being held a fixed small distance 56 behind the plate 44 .
  • CCD charged-coupled device
  • the transverse displacement 58 of each wavelet 50 at the CCD detector plane 54 from a collimated light reference position 60 is then used to calculate a wavefront slope at each position of the apertures 46 within the planar aperture array.
  • One acceptable approach is that used by Liang et al. in the aforementioned paper, where the wavefront is closely approximated using Zernike polynomials.
  • the apparatus 10 includes the projected beam 12 of linearly polarized light (S-component) emitted from a diode laser 66 (670 nm, 3 mW, by way of example).
  • the beam of light passes through an electromechanical shutter 68 , which controls the duration of light exposure on the eye 14 of the patient.
  • the exposure of the retina 18 of the eye 14 illustrated with reference again to FIG. 2. It is expected that alternate sources of light, for example, noncoherent and nonpolarized as well as alternate light-transmitting techniques, will be recognized by those skilled in the art without deviating from the teachings of the present invention. As herein described, the use of coherent light from a laser and polarization techniques are currently preferred.
  • lens 70 comprises a zoom lens for varying the focus and moving the focus location as desired.
  • the present invention avoids the aberration effects from the cornea, which typically dominate.
  • the lens 28 of the eye 14 contributes a relatively small aberration effect when compared with that of the cornea 24 .
  • selecting a lens with a short focal length would provide a large angle 13 , a well-focused point 78 on the surface of the cornea 24 , and fewer aberration effects from the cornea.
  • a large angle 13 results in an undesirably larger retinal spot 16 .
  • the small angle 13 herein described provides a larger focus point 78 on the cornea 24 but the more desirable smaller spot 16 on the retina 18 .
  • the spot 16 will depend on the wavelength, starting point size, and focal length of the lens 70 selected. In preferred embodiments of the present invention, lenses of approximate one-half meter are selected for the lens 70 . A 100-mm lens 70 has also been effectively used.
  • a mirror 74 and polarization beamsplitter 76 direct the beam 12 to a focus 78 on the anterior surface 20 of the cornea 24 .
  • the beam 12 focused on the anterior surface 22 of the cornea 24 , provides the spot 16 as a light source (about 1.5 milliradians in visual space, by way of example) on the retina 18 of the eye 14 being measured (FIG. 2).
  • a spot 16 provides an acceptable substitute for a diffraction limited spot typically sought.
  • a method for measuring vision characteristics of the eye 14 includes directing the beam 12 through the long-focal-length lens 70 for providing the small angle 13 (FIG.
  • the beam 12 is first focused at a fixed location 78 , without the eye or patient in place. All measuring equipment, the apparatus 10 , is arranged without the patient in place and at a convenient time prior to measuring. Then the patient is positioned such that the anterior surface of the eye 14 of a patient is located at the fixed location 78 , which in a preferred embodiment is the anterior surface of the cornea.
  • the laser power reaching the eye is physically limited to a maximum of 7 ⁇ W.
  • a laser pulse duration of 700 ms was used so that the total energy entering the eye would not exceed 4.9 ⁇ J.
  • the maximum permissible exposure to a laser at the wavelength used is 530 ⁇ J.
  • the probing laser energies effectively used in the present invention are two orders of magnitude below an “eye-safe” limit.
  • the light emitted by secondary source of radiation 16 produces the wavefront 40 , a distorted wavefront at the pupil plane due to the eye's aberrations. Diffuse reflection makes the returning light from the retina depolarized, containing not only an S-component but also a P-component polarized light.
  • the polarization beamsplitter 76 in front of the eye 14 will only let the P-component pass through it and downstream of the wavefront sensor 42 .
  • the S-component is essentially totally reflected toward the diode laser 66 .
  • the corneal reflection is reflected by the beamsplitter 76 and is thus rejected from the path 80 heading toward the wavefront sensor 42 .
  • the P-component of the aberrated wavefront 40 at the subject's pupil plane is then re-created by the combination of lens 82 and lens 84 , at a trial lens plane 86 (FIG. 1).
  • the diameter and the effective focal length of the two substantially identical lenses 82 and 84 are 40 and 120 mm, respectively.
  • lenses 82 and 84 forms an afocal image system with the eye's pupil 72 (the object plane) at the focal plane of the lens 82 , and the image plane, trial lens 86 , at the focal plane of the lens 84 .
  • lenses 88 and 90 also form an afocal image system with the possible trial lens 86 at the front focal plane of the lens 88 and the lens combination at the image plane at the back focal plane of the lens 90 .
  • the focal plane of the lens 90 is located at the plate 44 of the wavefront sensor 42 , earlier described with reference to FIG. 5.
  • lens 88 has an effective focal length of 80 mm.
  • Lens 90 has an effective focal length of 120 mm.
  • measured wavefront slopes leaving the eye 14 are re-created at the aperture plane 44 and magnified by a factor of 1.5.
  • Magnification of the diameter of the wavefront 40 at the detector plane 54 reduces the wavefront slopes by the same degree. This extends the dynamic range of eye aberrations over which the device can measure.
  • a trial lens of known refractive power inserted at this point should exactly compensate for a prescribed refractive error.
  • a perfect five-diopter lens placed at this location should remove five diopters of spherical curvature from an incident wavefront, without altering other aberrations that may exist in the wavefront.
  • the capability of inserting trial lenses at this location 86 extends the dynamic measurement range of the apparatus 10 , without affecting wavefront analyzing capability.
  • the aperture array 46 of the wavefront sensor 42 samples the incident wavefront 40 , which forms focus spots 62 on the detector plane 54 . This is repeated at the detector plane 54 for each aperture within the array 46 . As a result, a localized direction of the wavefront 40 is determined for each of a plurality of wavelets 50 within the array.
  • the use of lenslets 92 (as an alternate embodiment of apertures 46 alone), with a focal length of 87 mm and a dimension of 0.768 mm, forms an aerial image of the retinal light source (the spot 16 described earlier with reference to FIG. 2) on the detector plane 54 .
  • the lenslet 92 array would produce a regular array of focused spots on the image sensor.
  • the wave aberration in the eye will displace the focus spot 62 (FIG. 5), of each lenslet 92 from the reference position 60 to the measured position 50 in proportion to the local slopes of the wavefront 40 .
  • the wavefront sensor 42 measures the local wavefront slopes at an array of sampling locations across the pupil 72 , from which the wavefront 40 itself can be reconstructed.
  • a fixation target 94 may be used to ensure that the patient is looking along the optical axis of the apparatus 10 .
  • the patient is asked to fixate on the target 94 located at the focal plane of a lens 96 .
  • By linearly moving the optics combination 96 of the fixation target 94 it is possible to provide the eye's spherical correction, and hence to make the fixation target 94 clearly visible to the subject.
  • the image of the fixation target 94 is intentionally undercorrected for each patient to ensure that the measured eye 14 is focused at infinity.
  • the fixation target consists of a dark cross-hair and a number of concentric circles on a white background that is back-illuminated by a tungsten lamp.
  • the patient is asked to look at the center of the cross-hair.
  • the position of the eye 14 in reference to the optical axis is recorded by CCD camera 98 .
  • This CCD camera 98 is conjugate, in effect coupled, to the eye's pupil 72 through a second lens combination 100 , preferably mounted on the camera, and the lenses 82 , 84 .
  • the camera 98 is used to view the eye 14 for aligning the eye within the path of te beam 12 for assuring that the beam passes through the pupil 72 .
  • the camera 98 is also useful in an alternate embodiment of the present invention, for viewing the size of the spot 16 formed on the retina 18 as the user changes the focus point 78 through various anterior surface locations in obtaining an optimum size of the spot 16 .
  • the earlier described Zernike coefficients of an eye can be used as discriminating as fingerprints or DNA.
  • the Zernike coefficients for a person might be used for identification of that person for permitting access to a confidential area, allowing funds to be distributed through an ATM, and the like.
  • the present invention allows eye measurements for a passive subject, such as in the examination of a corpse or sedated animal.
  • the present invention is operable with human eyes, as herein described, as well as those of an animal, bird, or fish eyes, and in particular, nonbiological focusing optical systems such as those found in cameras.
  • the present invention is useful in developing optimized aspheric systems, where an aspheric element need to be designed last by observing and producing a single custom aspheric element that corrects the system.
  • the aspheric system may be designed on paper except for the correcting element, which would be developed experimentally using the present invention as herein described.
  • the design of afocal systems such as a telescope, a searchlight, or a projector which require an added corrective focus element will benefit from the present invention.

Abstract

An apparatus for measuring vision characteristics of an eye includes a laser for providing an optical beam and a focusing element for focusing the optical beam behind a retina of the eye for providing a finite source of secondary radiation on the retina of the eye. The secondary radiation is emitted from the retina as a reflected wavefront of radiation that passes outward from the eye. A polarizer is placed within a path of the optical beam for transmitting a polarized wavefront therethrough. A wavefront analyzer receives the polarized wavefront for measuring distortions associated therewith.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • This application is a divisional of application Ser. No. 09/919,374, filed Jul. 31, 2001, now U.S. Pat. No. 6,598,975, which itself is a continuation-in-part of application Ser. No. 09/665,748, filed Sep. 20, 2000, now U.S. Pat. No. 6,270,221, which is a continuation of application Ser. No. 09/274,672, filed Mar. 24, 1999, now abandoned, which claimed priority to Provisional Application having Ser. No. 60/097,086, filed on Aug. 19, 1998 for “Apparatus and Method for Measuring Vision Defects of a Human Eye,” commonly owned with the instant application.[0001]
  • BACKGROUND OF INVENTION
  • 1. Field of Invention [0002]
  • The invention relates generally to optical aberration measurement and correction, and in particular to projection techniques in the objective measurement and correction of the human eye using a wavefront sensor. [0003]
  • 2. Description of Background Art [0004]
  • There has been and continues to be a need to provide a person with improved visual acuity. Remodeling of the cornea using refractive laser surgery or intracorneal implants, adding synthetic lenses using intraocular lens implants or precision ground contact lenses or eye glasses provide known solutions. Further, it is known to correct vision astigmatically by surgical modification of myopic or hyperopic astigmatism through laser keratoplasty, keratomileusis, or photorefractive keratectomy. Laser sources are used to erode or ablate surfaces of the eye, typically reshaping the cornea. Prior to and during such surgery, precise measurements must be made to determine required surgical corrections. [0005]
  • The imprecise measurement technique of placing lenses of known refractive power anterior to the cornea and asking a patient which lens or lens combination provides the clearest vision has been improved with the use of autorefractometers, as described in U.S. Pat. No. 5,258,791 to Penny et al., or with the use of wavefront sensors as described by Liang et al. in “Objective Measurement of Wave Aberrations of the Human Eye with the Use of a Hartmann-Shack Wave-Front Sensor,” Journal of the Optical Society of America, Vol. 1, No. 7, July 1994, pp. 1949-1957, by way of example. Penny '791 discloses the use of autorefractometer measurements for determining the appropriate corneal surface reshaping to provide emmetropia, a condition of a normal eye when parallel rays are focused exactly on the retina and vision is optimum. Spatially resolved refraction data, in combination with measured existing surface contour of the anterior surface of the eye, enable a calculation of a detailed spatially resolved new contour that provides corrected vision. [0006]
  • It would be an improvement in the art if such vision correction could be made without the need for these contour data, and further without the need for feedback from the patient regarding an appropriate lens. Liang et al. disclose the use of a Hartmann-Shack wavefront sensor to measure ocular aberrations by measuring the wavefront emerging from the eye by retinal reflection of a focused laser light spot on the retina's fovea. A parallel beam of laser light passes through beam splitters and a lens pair that brings the beam to a focus point on the retina by the optics of the eye. Possible myopia or hyperopia of the tested eye is corrected by movement of a lens within the lens pair. The focused light on the fovea is then assumed to be diffusely reflected and acts as a point source located on the retina. The reflected light passes through the eye and forms a distorted wavefront in front of the eye that results from the ocular aberrations. The aberrated wavefront is then directed to the wavefront sensor. [0007]
  • A point source of radiation on the retina would be ideal for such measurements. However, when the perfect eye receives a collimated beam of light, the best possible image on the retina is a diffraction-limited spot. As illustrated by way of example, with Penny et al. and Liang et al., discussed above, and typical for those of skill in the art, collimated parallel beams are used with the optics of the eye being measured to achieve this diffraction-limited spot for such objective measurements. To do so requires that a setup for each patient include a corrective lens or lens combination and adjustments thereto for accommodating that patient's specific visual acuity. Providing a corrective or lens combination, as well as setting up for its use, becomes cumbersome and time consuming, and requires additional expense. Eliminating the need for such corrective optics is desirable and eliminates a variable within optical measurement systems that typically include many variables. Further, there is a need for providing optical characteristics of an eye without requiring feedback from the patient. By way of example, the patient may be a wild or domestic animal, living or dead. [0008]
  • SUMMARY OF INVENTION
  • In view of the foregoing background, it is therefore an object of the present invention to provide a refraction measurement system that easily accommodates the measurement of vision characteristics of the eye, even in the presence of finite refractive errors. [0009]
  • It is another object to improve upon the time required for a patient to be in a fixed position during examination, while at the same time providing a useful source of light on the retina of the eye to be measured regardless of the characteristics of the eye of that patient or other patients to be examined. [0010]
  • It is a further object to measure such characteristics without requiring patient or operator feedback. [0011]
  • These and other objects, advantages and features of the present invention, are provided by a method aspect of the invention for measuring optical characteristics of an optical system including the focusing of an optical beam proximate an anterior surface of the optical system, for placing a finite source of secondary radiation on a focal surface of the optical system, which secondary radiation is emitted from the focal surface as a reflected wavefront of radiation that passes through the optical system, transmitting the diffusely reflected wavefront onto a wavefront analyzer, and measuring characteristics of the optical system associated with the reflected wavefront. [0012]
  • In a preferred embodiment, the method includes the step of measuring defects of the eye, which includes the steps of focusing an optical beam onto an anterior surface of the eye, other than the retina, for providing a finite source of secondary radiation on the retina of the eye, which secondary source of radiation is emitted from the retina as a reflected wavefront of radiation that passes through the eye, directing the reflected wavefront onto a wavefront analyzer, and measuring distortions associated with the reflected wavefront. A preferred embodiment of the invention includes the step of focusing the projected optical beam on the anterior surface of the cornea. In an alternate embodiment the optical beam is focused behind the retina. [0013]
  • An apparatus for effectively performing such measurements includes means for focusing an optical beam onto an anterior surface of the optical system or eye, other than the retina, for providing a finite secondary source of radiation source on the focal surface, or retina of the eye, which finite secondary radiation source is emitted from the retina as a reflected wavefront of radiation that passes through the eye, means for directing the reflected wavefront onto a wavefront analyzer, and a wavefront analyzer for measuring distortions associated with the reflected wavefront. In one preferred embodiment of the present invention, a laser beam is focused onto the surface of the cornea with a long-focal-length lens, which converges the beam through a small angle for passing through the iris of the eye and providing a finite secondary source of radiation source on the retina of the eye, which finite secondary radiation source is emitted from the retina through the optics of the eye as the wavefront to be measured. In an alternate embodiment the apparatus comprises means for focusing the optical beam behind the retina[0014]
  • BRIEF DESCRIPTION OF DRAWINGS
  • A preferred embodiment of the invention as well as alternate embodiments are described by way of example with reference to the accompanying drawings. [0015]
  • FIG. 1 is a diagrammatic illustration of an apparatus for measuring visual defects of an eye, according to the present invention. [0016]
  • FIG. 2 is a diagrammatic illustration of an eye being measured by the apparatus of the present invention, with the focus on the cornea. [0017]
  • FIG. 2A is a diagrammatic illustration of an eye being measured by the apparatus of the present invention, with the focus behind the retina. [0018]
  • FIGS. 3A and 3B are diagrammatic illustrations of an ideal eye with perfect vision and an aberrated eye, respectively. [0019]
  • FIG. 4 is a diagrammatic illustration of an eye being measured with collimated light focused on the retina to a diffraction-limited spot. [0020]
  • FIG. 5 is a partial perspective view of a pinhole imaging plate and detector plane of a wavefront sensor used in a preferred embodiment of the present invention.[0021]
  • DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
  • The present invention will be described more fully hereinafter with reference to the accompanying drawings, in which preferred embodiments of the invention are shown. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. Like numbers refer to like elements throughout. [0022]
  • A preferred embodiment of a [0023] measurement apparatus 10 of the present invention is herein initially described with reference to the schematic diagram of FIG.1. A beam 12 of optical radiation is directed into an eye 14 to be measured, so that a small area or spot 16 is formed as a secondary source of radiation in the foveal region of the retina 18 (FIG. 2). Specifically, the beam 12 is focused through a small angle 13 onto an anterior surface 20 of the eye 14, other than the retina, and in a preferred embodiment of the present invention, focused on an anterior corneal surface 22 of the cornea 24 for further projection through the iris 26 and lens 28 and onto the retina 18.
  • In an alternate embodiment of the invention, a projected [0024] beam 12′ of optical radiation is directed into an eye 14′ to be measured, so that a small area or measurable spot 16′ is formed as a secondary radiation source in the foveal region of the retina 18′ (FIG. 2A). Specifically, the beam 12′ is focused through a small angle 13′ at a point behind the eye 14′, after passing through the iris 26′, the lens 28′, and the retina 18′.
  • By way of further background, consider an “ideal” [0025] eye 14 i with ideal vision, as illustrated with reference to FIG. 3A. The ideal eye 14 i, having the ideal cornea 24 i and ideal lens 28 i, will focus a collimated beam of light, illustrated with arrows 30 to a point 32, as the secondary radiation source, on the ideal retina 18 i. This point 32 would then be a point source of light that would be diffusely reflected back through the optics of the ideal eye 14 i as a sequence of plane waves 34. In actual fact, even an eye having perfect vision, as illustrated by way of example with reference to FIG. 4, will produce a diffraction-limited illuminated area or spot 36 as the secondary radiation source on the retina of the eye, under the best possible circumstances. In a typical eye, as illustrated with reference to FIG. 4, such a spot 36 is even larger, where most of the blurring will be due to finite aberrations found in typical eyes. By way of further example, in an aberrated eye 14 a, from the point source 32 distorted wavefronts 38 result, as illustrated with reference to FIG. 3B. Having to deal with a series of distorted wavefronts 38 resulting from aberrations, and further dealing with a blurring of such distorted wavefronts 38 resulting from diffraction effects and the finite aberrations of the eye, results in a spot 36 source of light rather than a point 32 source, representing one of the challenges in measuring the visual defects or an eye.
  • It is typical in the art of eye measurement to form a collimated beam and attempt to focus the collimated beam onto the retina, using lenses and lens combinations with the optics of the eye to produce the smallest [0026] possible spot 36, as earlier described with reference to FIG. 4. Using lenses and focusing techniques typically takes valuable time and includes multiple attempts to focus a spot on the retina with the use of various lenses and lens combinations to accommodate the unique vision of each patient being measured. With the present invention, and the understanding that most of the blurring results from the curvature of the cornea, the present invention eliminates the need to find lenses or lens combinations to minimize the size of the spot on the retina that is used as the secondary source of radiation.
  • With reference again to the embodiment described in FIGS. 1 and 2, the [0027] optical wavefronts 40 scattered from the retina 18 are transferred by a series of optical elements, which will be described in further detail in the following, to a wavefront sensor 42, which divides each incident wavefront into a group of “wavelets,” referred to herein with numeral 50, using an opaque plate 44 having a planar array of apertures 46 (FIG. 5). Further, the wavefront sensor 42 records the position 48 at which each wavelet 50 passing through the aperture 46 strikes a detector plane 54 such as a charged-coupled device (CCD), herein provided as one preferred embodiment, the plane being held a fixed small distance 56 behind the plate 44. The transverse displacement 58 of each wavelet 50 at the CCD detector plane 54 from a collimated light reference position 60 is then used to calculate a wavefront slope at each position of the apertures 46 within the planar aperture array. Alternate methods exist for using partial derivative data resulting from the measurements of the slope to calculate the wavefront 40. One acceptable approach is that used by Liang et al. in the aforementioned paper, where the wavefront is closely approximated using Zernike polynomials.
  • At each [0028] position 48, a spot 62 typically extending beyond the light measurement area of one CCD element 64 is produced. As earlier discussed, blurring and a large diffraction-limited spot make it difficult to make measurements. Thus reducing blurring improves measurement at the detector plane 54.
  • With reference again to FIG. 1, in one preferred embodiment of the present invention, the [0029] apparatus 10 includes the projected beam 12 of linearly polarized light (S-component) emitted from a diode laser 66 (670 nm, 3 mW, by way of example). The beam of light passes through an electromechanical shutter 68, which controls the duration of light exposure on the eye 14 of the patient. The exposure of the retina 18 of the eye 14 illustrated with reference again to FIG. 2. It is expected that alternate sources of light, for example, noncoherent and nonpolarized as well as alternate light-transmitting techniques, will be recognized by those skilled in the art without deviating from the teachings of the present invention. As herein described, the use of coherent light from a laser and polarization techniques are currently preferred.
  • When the [0030] shutter 68 is open, the projected beam 12, collimated light from the diode laser 66, is directed by a long focal length lens 70 for focusing on the anterior surface 22 of the cornea 24 of the eye 14 (FIG. 2), passing through the pupil 72 and lens 28 of the eye 14, and onto the retina 18 as the small spot 16. In an alternate embodiment, lens 70 comprises a zoom lens for varying the focus and moving the focus location as desired. By focusing on the cornea 24, the measurement is minimally dependent on the curvature of the cornea. However, other locations proximate the corneal surface are acceptable.
  • While diffraction and various aberrations are present, the present invention avoids the aberration effects from the cornea, which typically dominate. The [0031] lens 28 of the eye 14 contributes a relatively small aberration effect when compared with that of the cornea 24. Further, and with regard to the selection of lens 70, selecting a lens with a short focal length would provide a large angle 13, a well-focused point 78 on the surface of the cornea 24, and fewer aberration effects from the cornea. However, a large angle 13 results in an undesirably larger retinal spot 16. The small angle 13 herein described provides a larger focus point 78 on the cornea 24 but the more desirable smaller spot 16 on the retina 18. The spot 16 will depend on the wavelength, starting point size, and focal length of the lens 70 selected. In preferred embodiments of the present invention, lenses of approximate one-half meter are selected for the lens 70. A 100-mm lens 70 has also been effectively used.
  • In one preferred embodiment herein described, a [0032] mirror 74 and polarization beamsplitter 76 direct the beam 12 to a focus 78 on the anterior surface 20 of the cornea 24. The beam 12, focused on the anterior surface 22 of the cornea 24, provides the spot 16 as a light source (about 1.5 milliradians in visual space, by way of example) on the retina 18 of the eye 14 being measured (FIG. 2). Such a spot 16 provides an acceptable substitute for a diffraction limited spot typically sought. By way of one preferred example of use, a method for measuring vision characteristics of the eye 14 includes directing the beam 12 through the long-focal-length lens 70 for providing the small angle 13 (FIG. 2), about an optical path for passing the beam 12 through the pupil 72 of the eye 14. The beam 12 is first focused at a fixed location 78, without the eye or patient in place. All measuring equipment, the apparatus 10, is arranged without the patient in place and at a convenient time prior to measuring. Then the patient is positioned such that the anterior surface of the eye 14 of a patient is located at the fixed location 78, which in a preferred embodiment is the anterior surface of the cornea. This forms a finite source of secondary radiation, the spot 16, as herein described, on the retina 18 of the eye 14, which provides light emitted from the retina 18 and through the pupil 72 as a reflected wavefront, the wavefront 38 (FIG. 3B). This wavefront 38 is directed onto the wavefront analyzer 42 for measurement.
  • In a preferred embodiment, the laser power reaching the eye is physically limited to a maximum of 7 μW. In measurements on a human eye using the [0033] apparatus 10, a laser pulse duration of 700 ms was used so that the total energy entering the eye would not exceed 4.9 μJ. For comparison, according to the ANSI standard for direct “intrabeam” viewing, the maximum permissible exposure to a laser at the wavelength used is 530 μJ. Thus the probing laser energies effectively used in the present invention are two orders of magnitude below an “eye-safe” limit.
  • With reference again to FIG. 1, the light emitted by secondary source of [0034] radiation 16 produces the wavefront 40, a distorted wavefront at the pupil plane due to the eye's aberrations. Diffuse reflection makes the returning light from the retina depolarized, containing not only an S-component but also a P-component polarized light. The polarization beamsplitter 76 in front of the eye 14 will only let the P-component pass through it and downstream of the wavefront sensor 42. The S-component is essentially totally reflected toward the diode laser 66. Because the light reflected by corneal surface preserves the polarization of the incoming beam (S-polarized), the corneal reflection is reflected by the beamsplitter 76 and is thus rejected from the path 80 heading toward the wavefront sensor 42. The P-component of the aberrated wavefront 40 at the subject's pupil plane is then re-created by the combination of lens 82 and lens 84, at a trial lens plane 86 (FIG. 1). In one preferred embodiment, the diameter and the effective focal length of the two substantially identical lenses 82 and 84 are 40 and 120 mm, respectively. The combination of lenses 82 and 84 forms an afocal image system with the eye's pupil 72 (the object plane) at the focal plane of the lens 82, and the image plane, trial lens 86, at the focal plane of the lens 84. Similarly, lenses 88 and 90 also form an afocal image system with the possible trial lens 86 at the front focal plane of the lens 88 and the lens combination at the image plane at the back focal plane of the lens 90. The focal plane of the lens 90 is located at the plate 44 of the wavefront sensor 42, earlier described with reference to FIG. 5. In a preferred embodiment, lens 88 has an effective focal length of 80 mm. Lens 90 has an effective focal length of 120 mm. With the apparatus 10, measured wavefront slopes leaving the eye 14 are re-created at the aperture plane 44 and magnified by a factor of 1.5. Magnification of the diameter of the wavefront 40 at the detector plane 54 reduces the wavefront slopes by the same degree. This extends the dynamic range of eye aberrations over which the device can measure.
  • By way of further explanation about the trial lens location or [0035] plane 86, because the wavefront 40 leaving the eye 14 is re-created at this location 86 with unity magnification, a trial lens of known refractive power inserted at this point should exactly compensate for a prescribed refractive error. For example, a perfect five-diopter lens placed at this location should remove five diopters of spherical curvature from an incident wavefront, without altering other aberrations that may exist in the wavefront. The capability of inserting trial lenses at this location 86 extends the dynamic measurement range of the apparatus 10, without affecting wavefront analyzing capability.
  • In a preferred embodiment, and with reference again to FIG. 5, the [0036] aperture array 46 of the wavefront sensor 42 samples the incident wavefront 40, which forms focus spots 62 on the detector plane 54. This is repeated at the detector plane 54 for each aperture within the array 46. As a result, a localized direction of the wavefront 40 is determined for each of a plurality of wavelets 50 within the array. By way of example, the use of lenslets 92 (as an alternate embodiment of apertures 46 alone), with a focal length of 87 mm and a dimension of 0.768 mm, forms an aerial image of the retinal light source (the spot 16 described earlier with reference to FIG. 2) on the detector plane 54. If a plane wave, corresponding to an aberration-free eye, were measured, the lenslet 92 array would produce a regular array of focused spots on the image sensor. When the real eye 14 is measured, the wave aberration in the eye will displace the focus spot 62 (FIG. 5), of each lenslet 92 from the reference position 60 to the measured position 50 in proportion to the local slopes of the wavefront 40. The wavefront sensor 42 measures the local wavefront slopes at an array of sampling locations across the pupil 72, from which the wavefront 40 itself can be reconstructed.
  • As illustrated again with reference to FIG. 1, in an alternate embodiment of the present inventive methods, a [0037] fixation target 94 may be used to ensure that the patient is looking along the optical axis of the apparatus 10. The patient is asked to fixate on the target 94 located at the focal plane of a lens 96. By linearly moving the optics combination 96 of the fixation target 94, it is possible to provide the eye's spherical correction, and hence to make the fixation target 94 clearly visible to the subject. In one preferred use, the image of the fixation target 94 is intentionally undercorrected for each patient to ensure that the measured eye 14 is focused at infinity. By way of example, the fixation target consists of a dark cross-hair and a number of concentric circles on a white background that is back-illuminated by a tungsten lamp. The patient is asked to look at the center of the cross-hair. The position of the eye 14 in reference to the optical axis is recorded by CCD camera 98. This CCD camera 98 is conjugate, in effect coupled, to the eye's pupil 72 through a second lens combination 100, preferably mounted on the camera, and the lenses 82,84. In one method of te present invention, the camera 98 is used to view the eye 14 for aligning the eye within the path of te beam 12 for assuring that the beam passes through the pupil 72. The camera 98 is also useful in an alternate embodiment of the present invention, for viewing the size of the spot 16 formed on the retina 18 as the user changes the focus point 78 through various anterior surface locations in obtaining an optimum size of the spot 16.
  • By way of further example of effective uses of the present invention, the earlier described Zernike coefficients of an eye, taken collectively, can be used as discriminating as fingerprints or DNA. The Zernike coefficients for a person might be used for identification of that person for permitting access to a confidential area, allowing funds to be distributed through an ATM, and the like. Further, the present invention allows eye measurements for a passive subject, such as in the examination of a corpse or sedated animal. The present invention is operable with human eyes, as herein described, as well as those of an animal, bird, or fish eyes, and in particular, nonbiological focusing optical systems such as those found in cameras. The present invention is useful in developing optimized aspheric systems, where an aspheric element need to be designed last by observing and producing a single custom aspheric element that corrects the system. By way of example, the aspheric system may be designed on paper except for the correcting element, which would be developed experimentally using the present invention as herein described. The design of afocal systems such as a telescope, a searchlight, or a projector which require an added corrective focus element will benefit from the present invention. [0038]
  • Many modifications and other embodiments of the invention will come to the mind of one skilled in the art having the benefit of the teachings presented in the foregoing descriptions and the associated drawings. Therefore, it is to be understood that the invention is not to be limited to the specific embodiments disclosed, and that modifications and alternate embodiments are intended to be included within the scope of the appended claims. [0039]

Claims (22)

That which I claimed I:
1. An apparatus for measuring vision characteristics of an optical system, the apparatus comprising:
focusing means for focusing an optical beam proximate a posterior surface of the optical system for providing a finite source of secondary radiation on a focal surface, the posterior surface other than the focal surface, which secondary radiation is emitted from the focal surface as a reflected wavefront of radiation that passes through the optical system;
directing means for directing the reflected wavefront onto a wavefront analyzer; and
a wavefront analyzer for measuring distortions associated with the reflected wavefront.
2. The apparatus recited in claim 1, wherein the focusing means comprises a long-focal-length lens for converging the optical beam through a small angle and focusing the optical beam on the anterior surface.
3. The apparatus recited in claim 2, wherein the long-focal-length lens has a focal length of at least one-half meter.
4. The apparatus recited in claim 1, wherein the focusing means comprises a zoom lens for converging the optical beam through a small angle and varying the focusing of the optical beam onto various anterior surfaces.
5. The apparatus recited in claim 1, further comprising a laser for providing the optical beam.
6. The apparatus recited in claim 1, further comprising the a shutter operable from a closed position to an open position for controlling an amount of optical beam energy delivered to the optical system.
7. The apparatus recited in claim 1, wherein the wavefront analyzer comprises:
an opaque plate having an aperture therein for transmitting a portion of the emitted wavefront therethrough; and
a light-sensitive material downstream of and in spaced relation to the opaque plate for receiving the portion of the reflected wavefront projected as a finite image thereon.
8. The apparatus recited in claim 7, wherein the aperture comprises an aperture array and wherein the light-sensitive material comprises a CCD array.
9. The apparatus recited in claim 8, further comprising a lens carried within each of the plurality of apertures of the aperture array.
10. The apparatus recited in claim 1, further comprising polarizing means for polarizing the optical beam.
11. The apparatus recited in claim 10, further comprising a polarization beamsplitter for reflecting an S-component of the reflected wavefront and for transmitting a P-component of the reflected wavefront as a polarized wavefront therethrough.
12. The apparatus recited in claim 1, further comprising a camera positioned for viewing the focal surface.
13. An apparatus for measuring vision characteristics of an eye, the apparatus comprising:
a laser for providing an optical beam;
focusing means for focusing the optical beam behind a retina of the eye for providing a finite source of secondary radiation on the retina of the eye, which secondary radiation is emitted from the retina as a reflected wavefront of radiation that passes outward from the eye;
polarizing means placed within a path of the optical beam for transmitting a polarized wavefront therethrough; and
a wavefront analyzer receiving the polarized wavefront for measuring distortions associated therewith.
14. The apparatus recited in claim 13, wherein the focusing means comprises a long-focal-length lens for converging the optical beam through a small angle and focusing the optical beam on the anterior surface.
15. The apparatus recited in claim 14, wherein the long-focal-length lens has a 15 focal length of approximately one-half meter.
16. The apparatus recited in claim 13, further comprising the a shutter operable from a closed position to an open position for controlling an amount of optical beam energy delivered to the eye.
17. The apparatus recited in claim 13, wherein the wavefront analyzer comprises:
an opaque plate having an aperture therein for transmitting a portion of the emitted wavefront therethrough; and
a light-sensitive material downstream of and in spaced relation to the opaque plate for receiving the portion of the reflected wavefront projected as a finite image thereon.
18. The apparatus recited in claim 17, wherein the aperture comprises an aperture array and wherein the light-sensitive material comprises a CCD array.
19. The apparatus recited in claim 18, further comprising a lens carried within each aperture of the aperture array.
20. The apparatus recited in claim 13, further comprising a fixation target for viewing by a patient whose eye is being measured, the fixation target assuring that a patient whose eye is being measured is looking along a preferred direction.
21. The apparatus recited in claim 13, further comprising a camera positioned for viewing the focal surface.
22. A method for measuring vision defects of an eye comprising the steps of:
focusing an optical beam anterior of the retina of the eye, but not on the retina, for placing a finite source of secondary radiation on the retina, which secondary radiation is emitted from the retina as a reflected wavefront of radiation that passes through the eye;
projecting the reflected wavefront onto a wavefront analyzer; and
measuring distortions associated with the reflected wavefront.
US10/625,189 1998-08-19 2003-07-23 Apparatus and method for measuring vision defects of a human eye Abandoned US20040130677A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/625,189 US20040130677A1 (en) 1998-08-19 2003-07-23 Apparatus and method for measuring vision defects of a human eye

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9708698P 1998-08-19 1998-08-19
US27467299A 1999-03-24 1999-03-24
US09/665,748 US6270221B1 (en) 1998-08-19 2000-09-20 Apparatus and method for measuring vision defects of a human eye
US09/919,374 US6598975B2 (en) 1998-08-19 2001-07-31 Apparatus and method for measuring vision defects of a human eye
US10/625,189 US20040130677A1 (en) 1998-08-19 2003-07-23 Apparatus and method for measuring vision defects of a human eye

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09/919,374 Division US6598975B2 (en) 1998-08-19 2001-07-31 Apparatus and method for measuring vision defects of a human eye

Publications (1)

Publication Number Publication Date
US20040130677A1 true US20040130677A1 (en) 2004-07-08

Family

ID=27378293

Family Applications (2)

Application Number Title Priority Date Filing Date
US09/919,374 Expired - Lifetime US6598975B2 (en) 1998-08-19 2001-07-31 Apparatus and method for measuring vision defects of a human eye
US10/625,189 Abandoned US20040130677A1 (en) 1998-08-19 2003-07-23 Apparatus and method for measuring vision defects of a human eye

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US09/919,374 Expired - Lifetime US6598975B2 (en) 1998-08-19 2001-07-31 Apparatus and method for measuring vision defects of a human eye

Country Status (1)

Country Link
US (2) US6598975B2 (en)

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040156021A1 (en) * 1999-07-02 2004-08-12 Blum Ronald D. Method and apparatus for correcting vision using an electro-active phoropter
US20040223113A1 (en) * 2001-10-05 2004-11-11 Blum Ronald D. Hybrid electro-active lens
US20050140924A1 (en) * 1999-07-02 2005-06-30 E-Vision, Llc Electro-active multi-focal spectacle lens
US20050168687A1 (en) * 1999-07-02 2005-08-04 E-Vision, Llc System, apparatus, and method for correcting vision using an electro-active lens
US20050237485A1 (en) * 2004-04-21 2005-10-27 Blum Ronald D Method and apparatus for correcting vision
US20050270481A1 (en) * 2000-06-23 2005-12-08 E-Vision, L.L.C. Electro-optic lens with integrated components
US20060023004A1 (en) * 1999-07-02 2006-02-02 Duston Dwight P Method and system for electro-active spectacle lens design
US20070052920A1 (en) * 1999-07-02 2007-03-08 Stewart Wilber C Electro-active ophthalmic lens having an optical power blending region
US20070242173A1 (en) * 2004-11-02 2007-10-18 Blum Ronald D Electro-active spectacles and method of fabricating same
US20080024718A1 (en) * 2003-08-15 2008-01-31 Ronald Blum Enhanced electro-active lens system
US20080273166A1 (en) * 2007-05-04 2008-11-06 William Kokonaski Electronic eyeglass frame
US20090051873A1 (en) * 2007-08-23 2009-02-26 Ming Lai Eye Illumination Apparatus and Method
US7656509B2 (en) 2006-05-24 2010-02-02 Pixeloptics, Inc. Optical rangefinder for an electro-active lens
US20100274233A1 (en) * 1999-08-11 2010-10-28 Carl Zeiss Meditec Ag Method and device for performing online aberrometry in refractive eye correction
US7883207B2 (en) 2007-12-14 2011-02-08 Pixeloptics, Inc. Refractive-diffractive multifocal lens
US7883206B2 (en) 2007-03-07 2011-02-08 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US7926940B2 (en) 2007-02-23 2011-04-19 Pixeloptics, Inc. Advanced electro-active optic device
US7971994B2 (en) 2006-06-23 2011-07-05 Pixeloptics, Inc. Electro-active spectacle lenses
US7988286B2 (en) 1999-07-02 2011-08-02 E-Vision Llc Static progressive surface region in optical communication with a dynamic optic
US8092016B2 (en) 2007-03-29 2012-01-10 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US8154804B2 (en) 2008-03-25 2012-04-10 E-Vision Smart Optics, Inc. Electro-optic lenses for correction of higher order aberrations
US8215770B2 (en) 2007-02-23 2012-07-10 E-A Ophthalmics Ophthalmic dynamic aperture
US8317321B2 (en) 2007-07-03 2012-11-27 Pixeloptics, Inc. Multifocal lens with a diffractive optical power region
JP2013248257A (en) * 2012-06-01 2013-12-12 Canon Inc Ophthalmologic apparatus
US8778022B2 (en) 2004-11-02 2014-07-15 E-Vision Smart Optics Inc. Electro-active intraocular lenses
US8915588B2 (en) 2004-11-02 2014-12-23 E-Vision Smart Optics, Inc. Eyewear including a heads up display
US9122083B2 (en) 2005-10-28 2015-09-01 E-Vision Smart Optics, Inc. Eyewear docking station and electronic module
US9155614B2 (en) 2007-01-22 2015-10-13 E-Vision Smart Optics, Inc. Flexible dynamic electro-active lens
US9801709B2 (en) 2004-11-02 2017-10-31 E-Vision Smart Optics, Inc. Electro-active intraocular lenses
US10599006B2 (en) 2016-04-12 2020-03-24 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
US10613355B2 (en) 2007-05-04 2020-04-07 E-Vision, Llc Moisture-resistant eye wear
US11061252B2 (en) 2007-05-04 2021-07-13 E-Vision, Llc Hinge for electronic spectacles
US11397367B2 (en) 2016-04-12 2022-07-26 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030107814A1 (en) * 2001-12-11 2003-06-12 Altmann Griffith E. Method and apparatus for improving the dynamic range and accuracy of a Shack-Hartmann wavefront sensor
US6736509B2 (en) 2001-12-21 2004-05-18 Bausch And Lomb, Inc. Aberrometer illumination apparatus and method
AU2002953061A0 (en) * 2002-11-20 2002-12-19 Sola International Holdings Ltd Method for designing progressive lenses
US7556378B1 (en) 2003-04-10 2009-07-07 Tsontcho Ianchulev Intraoperative estimation of intraocular lens power
CA2561388C (en) 2004-04-20 2017-10-10 Wavetec Vision Systems, Inc. Integrated surgical microscope and wavefront sensor
US20060135952A1 (en) * 2004-12-21 2006-06-22 Curatu Eugene O Corrective intraocular lens and associated methods
KR100717528B1 (en) 2005-04-19 2007-05-11 주식회사 휴비츠 Auto refractometer using wavefront analyzation technique
US20080084541A1 (en) * 2006-10-06 2008-04-10 Ming Lai Ophthalmic system and method
US8092021B1 (en) 2007-01-26 2012-01-10 Aoptix Technologies, Inc. On-axis illumination for iris imaging
US8025399B2 (en) * 2007-01-26 2011-09-27 Aoptix Technologies, Inc. Combined iris imager and wavefront sensor
EP2144582B1 (en) 2007-05-11 2017-08-23 AMO Development, LLC Combined wavefront and topography systems and methods
US7575322B2 (en) * 2007-05-11 2009-08-18 Amo Development Llc. Auto-alignment and auto-focus system and method
US8016420B2 (en) 2007-05-17 2011-09-13 Amo Development Llc. System and method for illumination and fixation with ophthalmic diagnostic instruments
US7988290B2 (en) * 2007-06-27 2011-08-02 AMO Wavefront Sciences LLC. Systems and methods for measuring the shape and location of an object
US7976163B2 (en) * 2007-06-27 2011-07-12 Amo Wavefront Sciences Llc System and method for measuring corneal topography
US8317505B2 (en) 2007-08-21 2012-11-27 Johnson & Johnson Vision Care, Inc. Apparatus for formation of an ophthalmic lens precursor and lens
US8313828B2 (en) * 2008-08-20 2012-11-20 Johnson & Johnson Vision Care, Inc. Ophthalmic lens precursor and lens
US7905594B2 (en) * 2007-08-21 2011-03-15 Johnson & Johnson Vision Care, Inc. Free form ophthalmic lens
US8318055B2 (en) 2007-08-21 2012-11-27 Johnson & Johnson Vision Care, Inc. Methods for formation of an ophthalmic lens precursor and lens
US7594729B2 (en) 2007-10-31 2009-09-29 Wf Systems, Llc Wavefront sensor
US9417464B2 (en) 2008-08-20 2016-08-16 Johnson & Johnson Vision Care, Inc. Method and apparatus of forming a translating multifocal contact lens having a lower-lid contact surface
WO2010054268A2 (en) 2008-11-06 2010-05-14 Wavetec Vision Systems, Inc. Optical angular measurement system for ophthalmic applications and method for positioning of a toric intraocular lens with increased accuracy
US20100120013A1 (en) * 2008-11-07 2010-05-13 Mb Research Laboratories, Inc. Procedure for long term corneal culture
US8240849B2 (en) * 2009-03-31 2012-08-14 Johnson & Johnson Vision Care, Inc. Free form lens with refractive index variations
US8876290B2 (en) 2009-07-06 2014-11-04 Wavetec Vision Systems, Inc. Objective quality metric for ocular wavefront measurements
WO2011008606A1 (en) 2009-07-14 2011-01-20 Wavetec Vision Systems, Inc. Determination of the effective lens position of an intraocular lens using aphakic refractive power
WO2011008609A1 (en) 2009-07-14 2011-01-20 Wavetec Vision Systems, Inc. Ophthalmic surgery measurement system
US8807076B2 (en) 2010-03-12 2014-08-19 Johnson & Johnson Vision Care, Inc. Apparatus for vapor phase processing ophthalmic devices
US8622546B2 (en) 2011-06-08 2014-01-07 Amo Wavefront Sciences, Llc Method of locating valid light spots for optical measurement and optical measurement instrument employing method of locating valid light spots
US9072462B2 (en) 2012-09-27 2015-07-07 Wavetec Vision Systems, Inc. Geometric optical power measurement device
US9645412B2 (en) 2014-11-05 2017-05-09 Johnson & Johnson Vision Care Inc. Customized lens device and method
US10359643B2 (en) 2015-12-18 2019-07-23 Johnson & Johnson Vision Care, Inc. Methods for incorporating lens features and lenses having such features
CN109512380A (en) * 2018-11-02 2019-03-26 爱尔眼科医院集团股份有限公司 The method for making full retina dioptric topographic map based on wavefront sensing technique
US11364696B2 (en) 2020-09-18 2022-06-21 Johnson & Johnson Vision Care, Inc Apparatus for forming an ophthalmic lens

Citations (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880501A (en) * 1973-04-16 1975-04-29 Tropel Optical system for objective refractor for the eye
US4069823A (en) * 1976-04-19 1978-01-24 Viktor Leonidovich Isakov Apparatus for laser therapy
US4523821A (en) * 1981-12-18 1985-06-18 Carl-Zeiss-Stiftung Device for examining anterior sections of the eye
US4579430A (en) * 1982-12-11 1986-04-01 Carl-Zeiss-Stiftung Method and apparatus for forming an image of the ocular fundus
US4669466A (en) * 1985-01-16 1987-06-02 Lri L.P. Method and apparatus for analysis and correction of abnormal refractive errors of the eye
US4688941A (en) * 1984-06-15 1987-08-25 Office National D'etudes Et De Recherche Aerospatiales (Onera) Device for analyzing and correcting wavefront surfaces in real time using a polarization interferometer
US4702245A (en) * 1983-10-29 1987-10-27 Meditec-Reinhardt Thyzel Gmbh Pulsed laser for medical applications
US4718418A (en) * 1983-11-17 1988-01-12 Lri L.P. Apparatus for ophthalmological surgery
US4729372A (en) * 1983-11-17 1988-03-08 Lri L.P. Apparatus for performing ophthalmic laser surgery
US4750818A (en) * 1985-12-16 1988-06-14 Cochran Gregory M Phase conjugation method
US4764930A (en) * 1988-01-27 1988-08-16 Intelligent Surgical Lasers Multiwavelength laser source
US4838679A (en) * 1984-06-14 1989-06-13 Josef Bille Apparatus for, and method of, examining eyes
US4848340A (en) * 1988-02-10 1989-07-18 Intelligent Surgical Lasers Eyetracker and method of use
US4881808A (en) * 1988-02-10 1989-11-21 Intelligent Surgical Lasers Imaging system for surgical lasers
US4901718A (en) * 1988-02-02 1990-02-20 Intelligent Surgical Lasers 3-Dimensional laser beam guidance system
US4907586A (en) * 1988-03-31 1990-03-13 Intelligent Surgical Lasers Method for reshaping the eye
US4941093A (en) * 1985-09-12 1990-07-10 Summit Technology, Inc. Surface erosion using lasers
US4972836A (en) * 1989-12-18 1990-11-27 General Electric Company Motion detector for high-resolution magnetic resonance imaging
US4988348A (en) * 1989-05-26 1991-01-29 Intelligent Surgical Lasers, Inc. Method for reshaping the cornea
US4991953A (en) * 1989-02-09 1991-02-12 Eye Research Institute Of Retina Foundation Scanning laser vitreous camera
US5026977A (en) * 1989-04-05 1991-06-25 The Charles Stark Draper Laboratory, Inc. Wavefront sensing and correction with deformable mirror
US5026702A (en) * 1988-01-15 1991-06-25 Dr. Karl Thomae, Gmbh Morpholines and morpholine-N-oxides and pharmaceutical compositions containing these compounds
US5106183A (en) * 1987-11-25 1992-04-21 Taunton Technologies, Inc. Topography measuring apparatus
US5114628A (en) * 1990-01-24 1992-05-19 Ciba-Geigy Corporation Method for the manufacture of contact lenses
US5139022A (en) * 1990-10-26 1992-08-18 Philip Lempert Method and apparatus for imaging and analysis of ocular tissue
US5147352A (en) * 1987-07-08 1992-09-15 Alain Azema Optical system for use in a surgical apparatus
US5159361A (en) * 1989-03-09 1992-10-27 Par Technology Corporation Method and apparatus for obtaining the topography of an object
US5177511A (en) * 1986-11-08 1993-01-05 G. Rodenstock Instruments Gmbh Apparatus for producing images of an object and in particular for observing the rear portions of the eye
US5184157A (en) * 1989-06-29 1993-02-02 Kowa Company Limited Ophthalmic measurement apparatus
US5196006A (en) * 1989-04-25 1993-03-23 Summit Technology, Inc. Method and apparatus for excision endpoint control
US5198845A (en) * 1988-06-29 1993-03-30 G. Rodenstock Instrument Gmbh Apparatus for producing an image of an object (iii)
US5202709A (en) * 1990-03-14 1993-04-13 Kowa Company Ltd. Ophthalmological alignment and measurement apparatus
US5214456A (en) * 1991-10-09 1993-05-25 Computed Anatomy Incorporated Mapping of corneal topography with display of pupil perimeter
US5221834A (en) * 1991-06-28 1993-06-22 Eastman Kodak Company Method for providing feedback correction for an imaging device
US5229889A (en) * 1991-12-10 1993-07-20 Hughes Aircraft Company Simple adaptive optical system
US5233174A (en) * 1992-03-11 1993-08-03 Hughes Danbury Optical Systems, Inc. Wavefront sensor having a lenslet array as a null corrector
US5243367A (en) * 1990-07-24 1993-09-07 Fritz Spellitz Optical system for measuring the human cornea
US5246435A (en) * 1992-02-25 1993-09-21 Intelligent Surgical Lasers Method for removing cataractous material
US5258791A (en) * 1990-07-24 1993-11-02 General Electric Company Spatially resolved objective autorefractometer
US5279611A (en) * 1992-03-13 1994-01-18 Mcdonnell Peter J Laser shaping of ocular surfaces using ablation mask formed in situ
US5293871A (en) * 1993-05-05 1994-03-15 Cornell Research Foundation Inc. System for ultrasonically determining corneal layer thicknesses and shape
US5298971A (en) * 1992-09-23 1994-03-29 Industrial Technology Research Institute Lateral shear interferometer for testing aspheric surfaces
US5307097A (en) * 1992-11-05 1994-04-26 Kera-Metrics, Inc. Corneal topography system including single-direction shearing of holograph grating in orthogonal directions
US5324281A (en) * 1987-03-09 1994-06-28 Summit Technology, Inc. Laser reprofiling system employing a photodecomposable mask
US5334190A (en) * 1990-10-16 1994-08-02 Summit Technology, Inc. Laser thermokeratoplasty methods and apparatus
US5339121A (en) * 1991-11-01 1994-08-16 Visx, Incorported Rectilinear photokeratoscope
US5395356A (en) * 1993-06-04 1995-03-07 Summit Technology, Inc. Correction of presbyopia by photorefractive keratectomy
US5410376A (en) * 1994-02-04 1995-04-25 Pulse Medical Instruments Eye tracking method and apparatus
US5411501A (en) * 1993-06-04 1995-05-02 Summit Technology, Inc. Laser reprofiling system for correction of astigmatisms
US5423801A (en) * 1986-03-19 1995-06-13 Summit Technology, Inc. Laser corneal surgery
US5437658A (en) * 1992-10-07 1995-08-01 Summit Technology, Incorporated Method and system for laser thermokeratoplasty of the cornea
US5439462A (en) * 1992-02-25 1995-08-08 Intelligent Surgical Lasers Apparatus for removing cataractous material
US5442412A (en) * 1994-04-25 1995-08-15 Autonomous Technologies Corp. Patient responsive eye fixation target method and system
US5452031A (en) * 1993-05-05 1995-09-19 Boston Eye Technology, Inc. Contact lens and a method for manufacturing contact lens
US5461212A (en) * 1993-06-04 1995-10-24 Summit Technology, Inc. Astigmatic laser ablation of surfaces
US5491524A (en) * 1994-10-05 1996-02-13 Carl Zeiss, Inc. Optical coherence tomography corneal mapping apparatus
US5493391A (en) * 1994-07-11 1996-02-20 Sandia Corporation One dimensional wavefront distortion sensor comprising a lens array system
US5502518A (en) * 1993-09-09 1996-03-26 Scient Optics Inc Asymmetric aspheric contact lens
US5505723A (en) * 1994-02-10 1996-04-09 Summit Technology, Inc. Photo-refractive keratectomy
US5507741A (en) * 1983-11-17 1996-04-16 L'esperance, Jr.; Francis A. Ophthalmic method for laser surgery of the cornea
US5512966A (en) * 1993-06-24 1996-04-30 Orbtek, Inc. Ophthalmic pachymeter and method of making ophthalmic determinations
US5521657A (en) * 1992-05-01 1996-05-28 Summit Technology Inc. Method and system for topographic measurement by measuring the distance between a rigid reference member and a surface of an eye
US5548354A (en) * 1993-06-10 1996-08-20 Konan Common Co., Ltd. Method for observing and photographing a cornea and apparatus for the same
US5556395A (en) * 1993-05-07 1996-09-17 Visx Incorporated Method and system for laser treatment of refractive error using an offset image of a rotatable mask
US5563709A (en) * 1994-09-13 1996-10-08 Integrated Process Equipment Corp. Apparatus for measuring, thinning and flattening silicon structures
US5592246A (en) * 1994-02-24 1997-01-07 Keravision, Inc. Device and method for mapping objects
US5629765A (en) * 1995-12-15 1997-05-13 Adaptive Optics Associates, Inc. Wavefront measuring system with integral geometric reference (IGR)
US5632282A (en) * 1993-07-20 1997-05-27 Hay; S. Hutson Ocular disease detection apparatus
US5632742A (en) * 1994-04-25 1997-05-27 Autonomous Technologies Corp. Eye movement sensing method and system
US5673096A (en) * 1994-12-23 1997-09-30 Carl Zeiss Jena Gmbh Interferometric arrangement with diffractive optical element for measuring intraocular distances
US5711762A (en) * 1983-12-15 1998-01-27 Visx, Incorporated Laser surgery apparatus and method
US5722247A (en) * 1996-10-11 1998-03-03 Redi-Controls Inc. Recovery system for very high-pressure refrigerants
US5735283A (en) * 1996-10-09 1998-04-07 Snook; Richard Kieth Surgical keratometer system for measuring surface topography of a cornea during surgery
US5740803A (en) * 1997-03-07 1998-04-21 Autonomous Technologies Corporation Locating the center of the entrance pupil of an eye after pupil dilation
US5757463A (en) * 1993-06-29 1998-05-26 Canon Kabushiki Kaisha Eye examining apparatus scanning the eye with a light beam
US5777719A (en) * 1996-12-23 1998-07-07 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
US5784146A (en) * 1995-12-28 1998-07-21 Nidek Co., Ltd Ophthalmic measurement apparatus
US5786704A (en) * 1995-04-13 1998-07-28 Mirae Corporation Metallic tray unit for testing a semiconductor device
US5822035A (en) * 1996-08-30 1998-10-13 Heidelberg Engineering Optische Messysteme Gmbh Ellipsometer
US5825476A (en) * 1994-06-14 1998-10-20 Visionix Ltd. Apparatus for mapping optical elements
US5861955A (en) * 1994-04-25 1999-01-19 Medjet Inc. Topographical cornea mapping for corneal vision correction
US5864381A (en) * 1996-07-10 1999-01-26 Sandia Corporation Automated pupil remapping with binary optics
US5920373A (en) * 1997-09-24 1999-07-06 Heidelberg Engineering Optische Messysteme Gmbh Method and apparatus for determining optical characteristics of a cornea
US5936720A (en) * 1996-07-10 1999-08-10 Neal; Daniel R. Beam characterization by wavefront sensor
US5943117A (en) * 1996-11-22 1999-08-24 Jozef F. Van de Velde Scanning laser ophthalmoscope for retinal microphotocoagulation and measurement of wavefront aberrations
US5963300A (en) * 1998-02-17 1999-10-05 Amt Technologies, Corp. Ocular biometer
US5966197A (en) * 1998-04-21 1999-10-12 Visx, Incorporated Linear array eye tracker
US6043885A (en) * 1996-07-12 2000-03-28 Essilor International Fringe deflectometry apparatus and method
US6050687A (en) * 1999-06-11 2000-04-18 20/10 Perfect Vision Optische Geraete Gmbh Method and apparatus for measurement of the refractive properties of the human eye
US6057913A (en) * 1997-02-05 2000-05-02 Mems Optical Inc. Compact shearing wavefront sensor and method
US6086204A (en) * 1999-09-20 2000-07-11 Magnante; Peter C. Methods and devices to design and fabricate surfaces on contact lenses and on corneal tissue that correct the eye's optical aberrations
US6270221B1 (en) * 1998-08-19 2001-08-07 Alcon Universal Ltd. Apparatus and method for measuring vision defects of a human eye

Patent Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880501A (en) * 1973-04-16 1975-04-29 Tropel Optical system for objective refractor for the eye
US4069823A (en) * 1976-04-19 1978-01-24 Viktor Leonidovich Isakov Apparatus for laser therapy
US4523821A (en) * 1981-12-18 1985-06-18 Carl-Zeiss-Stiftung Device for examining anterior sections of the eye
US4579430A (en) * 1982-12-11 1986-04-01 Carl-Zeiss-Stiftung Method and apparatus for forming an image of the ocular fundus
US4702245A (en) * 1983-10-29 1987-10-27 Meditec-Reinhardt Thyzel Gmbh Pulsed laser for medical applications
US4729372A (en) * 1983-11-17 1988-03-08 Lri L.P. Apparatus for performing ophthalmic laser surgery
US5507741A (en) * 1983-11-17 1996-04-16 L'esperance, Jr.; Francis A. Ophthalmic method for laser surgery of the cornea
US4718418A (en) * 1983-11-17 1988-01-12 Lri L.P. Apparatus for ophthalmological surgery
US5735843A (en) * 1983-12-15 1998-04-07 Visx, Incorporated Laser surgery apparatus and method
US5711762A (en) * 1983-12-15 1998-01-27 Visx, Incorporated Laser surgery apparatus and method
US4838679A (en) * 1984-06-14 1989-06-13 Josef Bille Apparatus for, and method of, examining eyes
US4688941A (en) * 1984-06-15 1987-08-25 Office National D'etudes Et De Recherche Aerospatiales (Onera) Device for analyzing and correcting wavefront surfaces in real time using a polarization interferometer
US4721379A (en) * 1985-01-16 1988-01-26 Lri L.P. Apparatus for analysis and correction of abnormal refractive errors of the eye
US4669466A (en) * 1985-01-16 1987-06-02 Lri L.P. Method and apparatus for analysis and correction of abnormal refractive errors of the eye
US4941093A (en) * 1985-09-12 1990-07-10 Summit Technology, Inc. Surface erosion using lasers
US4750818A (en) * 1985-12-16 1988-06-14 Cochran Gregory M Phase conjugation method
US5423801A (en) * 1986-03-19 1995-06-13 Summit Technology, Inc. Laser corneal surgery
US5177511A (en) * 1986-11-08 1993-01-05 G. Rodenstock Instruments Gmbh Apparatus for producing images of an object and in particular for observing the rear portions of the eye
US5324281A (en) * 1987-03-09 1994-06-28 Summit Technology, Inc. Laser reprofiling system employing a photodecomposable mask
US5147352A (en) * 1987-07-08 1992-09-15 Alain Azema Optical system for use in a surgical apparatus
US5106183A (en) * 1987-11-25 1992-04-21 Taunton Technologies, Inc. Topography measuring apparatus
US5026702A (en) * 1988-01-15 1991-06-25 Dr. Karl Thomae, Gmbh Morpholines and morpholine-N-oxides and pharmaceutical compositions containing these compounds
US4764930A (en) * 1988-01-27 1988-08-16 Intelligent Surgical Lasers Multiwavelength laser source
US4901718A (en) * 1988-02-02 1990-02-20 Intelligent Surgical Lasers 3-Dimensional laser beam guidance system
US4881808A (en) * 1988-02-10 1989-11-21 Intelligent Surgical Lasers Imaging system for surgical lasers
US4848340A (en) * 1988-02-10 1989-07-18 Intelligent Surgical Lasers Eyetracker and method of use
US4907586A (en) * 1988-03-31 1990-03-13 Intelligent Surgical Lasers Method for reshaping the eye
US5198845A (en) * 1988-06-29 1993-03-30 G. Rodenstock Instrument Gmbh Apparatus for producing an image of an object (iii)
US4991953A (en) * 1989-02-09 1991-02-12 Eye Research Institute Of Retina Foundation Scanning laser vitreous camera
US5159361A (en) * 1989-03-09 1992-10-27 Par Technology Corporation Method and apparatus for obtaining the topography of an object
US5026977A (en) * 1989-04-05 1991-06-25 The Charles Stark Draper Laboratory, Inc. Wavefront sensing and correction with deformable mirror
US5196006A (en) * 1989-04-25 1993-03-23 Summit Technology, Inc. Method and apparatus for excision endpoint control
US4988348A (en) * 1989-05-26 1991-01-29 Intelligent Surgical Lasers, Inc. Method for reshaping the cornea
US5184157A (en) * 1989-06-29 1993-02-02 Kowa Company Limited Ophthalmic measurement apparatus
US4972836A (en) * 1989-12-18 1990-11-27 General Electric Company Motion detector for high-resolution magnetic resonance imaging
US5114628A (en) * 1990-01-24 1992-05-19 Ciba-Geigy Corporation Method for the manufacture of contact lenses
US5202709A (en) * 1990-03-14 1993-04-13 Kowa Company Ltd. Ophthalmological alignment and measurement apparatus
US5243367A (en) * 1990-07-24 1993-09-07 Fritz Spellitz Optical system for measuring the human cornea
US5258791A (en) * 1990-07-24 1993-11-02 General Electric Company Spatially resolved objective autorefractometer
US5334190A (en) * 1990-10-16 1994-08-02 Summit Technology, Inc. Laser thermokeratoplasty methods and apparatus
US5404884A (en) * 1990-10-26 1995-04-11 Lempert; Philip Method and apparatus for imaging and analysis of corneal tissue
US5139022A (en) * 1990-10-26 1992-08-18 Philip Lempert Method and apparatus for imaging and analysis of ocular tissue
US5221834A (en) * 1991-06-28 1993-06-22 Eastman Kodak Company Method for providing feedback correction for an imaging device
US5214456A (en) * 1991-10-09 1993-05-25 Computed Anatomy Incorporated Mapping of corneal topography with display of pupil perimeter
US5339121A (en) * 1991-11-01 1994-08-16 Visx, Incorported Rectilinear photokeratoscope
US5229889A (en) * 1991-12-10 1993-07-20 Hughes Aircraft Company Simple adaptive optical system
US5439462A (en) * 1992-02-25 1995-08-08 Intelligent Surgical Lasers Apparatus for removing cataractous material
US5246435A (en) * 1992-02-25 1993-09-21 Intelligent Surgical Lasers Method for removing cataractous material
US5233174A (en) * 1992-03-11 1993-08-03 Hughes Danbury Optical Systems, Inc. Wavefront sensor having a lenslet array as a null corrector
US5279611A (en) * 1992-03-13 1994-01-18 Mcdonnell Peter J Laser shaping of ocular surfaces using ablation mask formed in situ
US5521657A (en) * 1992-05-01 1996-05-28 Summit Technology Inc. Method and system for topographic measurement by measuring the distance between a rigid reference member and a surface of an eye
US5298971A (en) * 1992-09-23 1994-03-29 Industrial Technology Research Institute Lateral shear interferometer for testing aspheric surfaces
US5437658A (en) * 1992-10-07 1995-08-01 Summit Technology, Incorporated Method and system for laser thermokeratoplasty of the cornea
US5307097A (en) * 1992-11-05 1994-04-26 Kera-Metrics, Inc. Corneal topography system including single-direction shearing of holograph grating in orthogonal directions
US5293871A (en) * 1993-05-05 1994-03-15 Cornell Research Foundation Inc. System for ultrasonically determining corneal layer thicknesses and shape
US5452031A (en) * 1993-05-05 1995-09-19 Boston Eye Technology, Inc. Contact lens and a method for manufacturing contact lens
US5556395A (en) * 1993-05-07 1996-09-17 Visx Incorporated Method and system for laser treatment of refractive error using an offset image of a rotatable mask
US5395356A (en) * 1993-06-04 1995-03-07 Summit Technology, Inc. Correction of presbyopia by photorefractive keratectomy
US5411501A (en) * 1993-06-04 1995-05-02 Summit Technology, Inc. Laser reprofiling system for correction of astigmatisms
US5461212A (en) * 1993-06-04 1995-10-24 Summit Technology, Inc. Astigmatic laser ablation of surfaces
US5548354A (en) * 1993-06-10 1996-08-20 Konan Common Co., Ltd. Method for observing and photographing a cornea and apparatus for the same
US5512966A (en) * 1993-06-24 1996-04-30 Orbtek, Inc. Ophthalmic pachymeter and method of making ophthalmic determinations
US5512965A (en) * 1993-06-24 1996-04-30 Orbtek, Inc. Ophthalmic instrument and method of making ophthalmic determinations using Scheimpflug corrections
US5757463A (en) * 1993-06-29 1998-05-26 Canon Kabushiki Kaisha Eye examining apparatus scanning the eye with a light beam
US5632282A (en) * 1993-07-20 1997-05-27 Hay; S. Hutson Ocular disease detection apparatus
US5570142A (en) * 1993-09-09 1996-10-29 Scientific Optics, Inc. Asymmetric aspheric contact lens
US5502518A (en) * 1993-09-09 1996-03-26 Scient Optics Inc Asymmetric aspheric contact lens
US5410376A (en) * 1994-02-04 1995-04-25 Pulse Medical Instruments Eye tracking method and apparatus
US5505723A (en) * 1994-02-10 1996-04-09 Summit Technology, Inc. Photo-refractive keratectomy
US5592246A (en) * 1994-02-24 1997-01-07 Keravision, Inc. Device and method for mapping objects
US5632742A (en) * 1994-04-25 1997-05-27 Autonomous Technologies Corp. Eye movement sensing method and system
US5442412A (en) * 1994-04-25 1995-08-15 Autonomous Technologies Corp. Patient responsive eye fixation target method and system
US5861955A (en) * 1994-04-25 1999-01-19 Medjet Inc. Topographical cornea mapping for corneal vision correction
US5825476A (en) * 1994-06-14 1998-10-20 Visionix Ltd. Apparatus for mapping optical elements
US5493391A (en) * 1994-07-11 1996-02-20 Sandia Corporation One dimensional wavefront distortion sensor comprising a lens array system
US5563709A (en) * 1994-09-13 1996-10-08 Integrated Process Equipment Corp. Apparatus for measuring, thinning and flattening silicon structures
US5491524A (en) * 1994-10-05 1996-02-13 Carl Zeiss, Inc. Optical coherence tomography corneal mapping apparatus
US5673096A (en) * 1994-12-23 1997-09-30 Carl Zeiss Jena Gmbh Interferometric arrangement with diffractive optical element for measuring intraocular distances
US5786704A (en) * 1995-04-13 1998-07-28 Mirae Corporation Metallic tray unit for testing a semiconductor device
US5629765A (en) * 1995-12-15 1997-05-13 Adaptive Optics Associates, Inc. Wavefront measuring system with integral geometric reference (IGR)
US5784146A (en) * 1995-12-28 1998-07-21 Nidek Co., Ltd Ophthalmic measurement apparatus
US5936720A (en) * 1996-07-10 1999-08-10 Neal; Daniel R. Beam characterization by wavefront sensor
US5864381A (en) * 1996-07-10 1999-01-26 Sandia Corporation Automated pupil remapping with binary optics
US6043885A (en) * 1996-07-12 2000-03-28 Essilor International Fringe deflectometry apparatus and method
US5822035A (en) * 1996-08-30 1998-10-13 Heidelberg Engineering Optische Messysteme Gmbh Ellipsometer
US5735283A (en) * 1996-10-09 1998-04-07 Snook; Richard Kieth Surgical keratometer system for measuring surface topography of a cornea during surgery
US5722247A (en) * 1996-10-11 1998-03-03 Redi-Controls Inc. Recovery system for very high-pressure refrigerants
US5943117A (en) * 1996-11-22 1999-08-24 Jozef F. Van de Velde Scanning laser ophthalmoscope for retinal microphotocoagulation and measurement of wavefront aberrations
US5949521A (en) * 1996-12-23 1999-09-07 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
US5777719A (en) * 1996-12-23 1998-07-07 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
US6095651A (en) * 1996-12-23 2000-08-01 University Of Rochester Method and apparatus for improving vision and the resolution of retinal images
US6057913A (en) * 1997-02-05 2000-05-02 Mems Optical Inc. Compact shearing wavefront sensor and method
US5740803A (en) * 1997-03-07 1998-04-21 Autonomous Technologies Corporation Locating the center of the entrance pupil of an eye after pupil dilation
US5920373A (en) * 1997-09-24 1999-07-06 Heidelberg Engineering Optische Messysteme Gmbh Method and apparatus for determining optical characteristics of a cornea
US5963300A (en) * 1998-02-17 1999-10-05 Amt Technologies, Corp. Ocular biometer
US5966197A (en) * 1998-04-21 1999-10-12 Visx, Incorporated Linear array eye tracker
US6270221B1 (en) * 1998-08-19 2001-08-07 Alcon Universal Ltd. Apparatus and method for measuring vision defects of a human eye
US6050687A (en) * 1999-06-11 2000-04-18 20/10 Perfect Vision Optische Geraete Gmbh Method and apparatus for measurement of the refractive properties of the human eye
US6086204A (en) * 1999-09-20 2000-07-11 Magnante; Peter C. Methods and devices to design and fabricate surfaces on contact lenses and on corneal tissue that correct the eye's optical aberrations

Cited By (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8727531B2 (en) 1999-07-02 2014-05-20 E-Vision, Llc Electro-active opthalmic lens having an optical power blending region
US7997733B2 (en) 1999-07-02 2011-08-16 E-Vision, Llc System, apparatus and method for correcting vision with an adaptive optic
US20050140924A1 (en) * 1999-07-02 2005-06-30 E-Vision, Llc Electro-active multi-focal spectacle lens
US20050168687A1 (en) * 1999-07-02 2005-08-04 E-Vision, Llc System, apparatus, and method for correcting vision using an electro-active lens
US9323101B2 (en) 1999-07-02 2016-04-26 E-Vision Smart Optics, Inc. Electro-active opthalmic lens having an optical power blending region
US7988286B2 (en) 1999-07-02 2011-08-02 E-Vision Llc Static progressive surface region in optical communication with a dynamic optic
US20060023004A1 (en) * 1999-07-02 2006-02-02 Duston Dwight P Method and system for electro-active spectacle lens design
US20070052920A1 (en) * 1999-07-02 2007-03-08 Stewart Wilber C Electro-active ophthalmic lens having an optical power blending region
US7188948B2 (en) * 1999-07-02 2007-03-13 E-Vision, Llc System, apparatus and method for correcting vision with an adaptive optic
US20070146627A1 (en) * 1999-07-02 2007-06-28 E-Vision, Llc System, apparatus and method for correcting vision using an electro-active lens
US9500883B2 (en) 1999-07-02 2016-11-22 E-Vision Smart Optics, Inc. Electro-active opthalmic lens having an optical power blending region
US20070242224A1 (en) * 1999-07-02 2007-10-18 Blum Ronald D Method and apparatus for correcting vision using an electro-active phoropter
US8029134B2 (en) 1999-07-02 2011-10-04 E-Vision, Llc System, apparatus, and method for correcting vision using an electro-active lens
US8333470B2 (en) 1999-07-02 2012-12-18 E-Vision Llc Electro-active opthalmic lens having an optical power blending region
US7775660B2 (en) 1999-07-02 2010-08-17 E-Vision Llc Electro-active ophthalmic lens having an optical power blending region
US8641191B2 (en) 1999-07-02 2014-02-04 E-Vision, Llc Static progressive surface region in optical communication with a dynamic optic
US7731358B2 (en) 1999-07-02 2010-06-08 E-Vision Llc System, apparatus, and method for correcting vision using an electro-active lens
US7744214B2 (en) 1999-07-02 2010-06-29 E-Vision Llc System, apparatus and method for correcting vision with an adaptive optic
US8047651B2 (en) 1999-07-02 2011-11-01 E-Vision Inc. Electro-active opthalmic lens having an optical power blending region
US20040156021A1 (en) * 1999-07-02 2004-08-12 Blum Ronald D. Method and apparatus for correcting vision using an electro-active phoropter
US9411173B1 (en) 1999-07-02 2016-08-09 E-Vision Smart Optics, Inc. Electro-active opthalmic lens having an optical power blending region
US20100274233A1 (en) * 1999-08-11 2010-10-28 Carl Zeiss Meditec Ag Method and device for performing online aberrometry in refractive eye correction
US8356897B2 (en) 1999-08-11 2013-01-22 Carl Zeiss Meditec Ag Method and device for performing online aberrometry in refractive eye correction
US8029136B2 (en) 1999-08-11 2011-10-04 Carl Zeiss Meditec Ag Method and device for performing online aberrometry in refractive eye correction
US20050270481A1 (en) * 2000-06-23 2005-12-08 E-Vision, L.L.C. Electro-optic lens with integrated components
US20040223113A1 (en) * 2001-10-05 2004-11-11 Blum Ronald D. Hybrid electro-active lens
US20080024718A1 (en) * 2003-08-15 2008-01-31 Ronald Blum Enhanced electro-active lens system
US20050237485A1 (en) * 2004-04-21 2005-10-27 Blum Ronald D Method and apparatus for correcting vision
US10159563B2 (en) 2004-11-02 2018-12-25 E-Vision Smart Optics, Inc. Eyewear including a detachable power supply and a display
US11422389B2 (en) 2004-11-02 2022-08-23 E-Vision Smart Optics, Inc. Eyewear including a remote control camera
US11144090B2 (en) 2004-11-02 2021-10-12 E-Vision Smart Optics, Inc. Eyewear including a camera or display
US10852766B2 (en) 2004-11-02 2020-12-01 E-Vision Smart Optics, Inc. Electro-active elements with crossed linear electrodes
US10795411B2 (en) 2004-11-02 2020-10-06 E-Vision Smart Optics, Inc. Eyewear including a remote control camera and a docking station
US20070242173A1 (en) * 2004-11-02 2007-10-18 Blum Ronald D Electro-active spectacles and method of fabricating same
US10729539B2 (en) 2004-11-02 2020-08-04 E-Vision Smart Optics, Inc. Electro-chromic ophthalmic devices
US10379575B2 (en) 2004-11-02 2019-08-13 E-Vision Smart Optics, Inc. Eyewear including a remote control camera and a docking station
US11822155B2 (en) 2004-11-02 2023-11-21 E-Vision Smart Optics, Inc. Eyewear including a remote control camera
US9124796B2 (en) 2004-11-02 2015-09-01 E-Vision Smart Optics, Inc. Eyewear including a remote control camera
US9801709B2 (en) 2004-11-02 2017-10-31 E-Vision Smart Optics, Inc. Electro-active intraocular lenses
US10092395B2 (en) 2004-11-02 2018-10-09 E-Vision Smart Optics, Inc. Electro-active lens with crossed linear electrodes
US10172704B2 (en) 2004-11-02 2019-01-08 E-Vision Smart Optics, Inc. Methods and apparatus for actuating an ophthalmic lens in response to ciliary muscle motion
US11262796B2 (en) 2004-11-02 2022-03-01 E-Vision Smart Optics, Inc. Eyewear including a detachable power supply and display
US8931896B2 (en) 2004-11-02 2015-01-13 E-Vision Smart Optics Inc. Eyewear including a docking station
US10126569B2 (en) 2004-11-02 2018-11-13 E-Vision Smart Optics Inc. Flexible electro-active lens
US8915588B2 (en) 2004-11-02 2014-12-23 E-Vision Smart Optics, Inc. Eyewear including a heads up display
US8778022B2 (en) 2004-11-02 2014-07-15 E-Vision Smart Optics Inc. Electro-active intraocular lenses
US10114235B2 (en) 2005-10-28 2018-10-30 E-Vision Smart Optics, Inc. Eyewear docking station and electronic module
US9122083B2 (en) 2005-10-28 2015-09-01 E-Vision Smart Optics, Inc. Eyewear docking station and electronic module
US8337014B2 (en) 2006-05-03 2012-12-25 Pixeloptics, Inc. Electronic eyeglass frame
US7656509B2 (en) 2006-05-24 2010-02-02 Pixeloptics, Inc. Optical rangefinder for an electro-active lens
US8408699B2 (en) 2006-06-23 2013-04-02 Pixeloptics, Inc. Electro-active spectacle lenses
US7971994B2 (en) 2006-06-23 2011-07-05 Pixeloptics, Inc. Electro-active spectacle lenses
US11474380B2 (en) 2007-01-22 2022-10-18 E-Vision Smart Optics, Inc. Flexible electro-active lens
US9155614B2 (en) 2007-01-22 2015-10-13 E-Vision Smart Optics, Inc. Flexible dynamic electro-active lens
US7926940B2 (en) 2007-02-23 2011-04-19 Pixeloptics, Inc. Advanced electro-active optic device
US8215770B2 (en) 2007-02-23 2012-07-10 E-A Ophthalmics Ophthalmic dynamic aperture
US7883206B2 (en) 2007-03-07 2011-02-08 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US8197063B2 (en) 2007-03-07 2012-06-12 Pixeloptics, Inc. Refractive-diffractive multifocal lens
US8308295B2 (en) 2007-03-07 2012-11-13 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and discontinuity
US8434865B2 (en) 2007-03-07 2013-05-07 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US8662665B2 (en) 2007-03-07 2014-03-04 Pixeloptics, Inc. Refractive-diffractive multifocal lens
US8092016B2 (en) 2007-03-29 2012-01-10 Pixeloptics, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US9033494B2 (en) 2007-03-29 2015-05-19 Mitsui Chemicals, Inc. Multifocal lens having a progressive optical power region and a discontinuity
US11061252B2 (en) 2007-05-04 2021-07-13 E-Vision, Llc Hinge for electronic spectacles
US20080273166A1 (en) * 2007-05-04 2008-11-06 William Kokonaski Electronic eyeglass frame
US9028062B2 (en) 2007-05-04 2015-05-12 Mitsui Chemicals, Inc. Electronic eyeglass frame
US11586057B2 (en) 2007-05-04 2023-02-21 E-Vision, Llc Moisture-resistant eye wear
US8708483B2 (en) 2007-05-04 2014-04-29 Pixeloptics, Inc. Electronic eyeglass frame
US10613355B2 (en) 2007-05-04 2020-04-07 E-Vision, Llc Moisture-resistant eye wear
US8317321B2 (en) 2007-07-03 2012-11-27 Pixeloptics, Inc. Multifocal lens with a diffractive optical power region
US9411172B2 (en) 2007-07-03 2016-08-09 Mitsui Chemicals, Inc. Multifocal lens with a diffractive optical power region
US8157378B2 (en) * 2007-08-23 2012-04-17 Bausch & Lomb Incorporated Eye illumination apparatus and method
US20090051873A1 (en) * 2007-08-23 2009-02-26 Ming Lai Eye Illumination Apparatus and Method
US7883207B2 (en) 2007-12-14 2011-02-08 Pixeloptics, Inc. Refractive-diffractive multifocal lens
US8154804B2 (en) 2008-03-25 2012-04-10 E-Vision Smart Optics, Inc. Electro-optic lenses for correction of higher order aberrations
US10598960B2 (en) 2012-01-06 2020-03-24 E-Vision Smart Optics, Inc. Eyewear docking station and electronic module
US11487138B2 (en) 2012-01-06 2022-11-01 E-Vision Smart Optics, Inc. Eyewear docking station and electronic module
JP2013248257A (en) * 2012-06-01 2013-12-12 Canon Inc Ophthalmologic apparatus
US11397367B2 (en) 2016-04-12 2022-07-26 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
US11054714B2 (en) 2016-04-12 2021-07-06 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
US10599006B2 (en) 2016-04-12 2020-03-24 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges
US11662642B2 (en) 2016-04-12 2023-05-30 E-Vision Smart Optics, Inc. Electro-active lenses with raised resistive bridges

Also Published As

Publication number Publication date
US6598975B2 (en) 2003-07-29
US20030020872A1 (en) 2003-01-30

Similar Documents

Publication Publication Date Title
US6598975B2 (en) Apparatus and method for measuring vision defects of a human eye
US6270221B1 (en) Apparatus and method for measuring vision defects of a human eye
US6439720B1 (en) Method and apparatus for measuring optical aberrations of the human eye
US7036934B1 (en) Wavefront sensor having multi-power modes, independent adjustment camera, and accommodation range measurement
CA2311818C (en) Objective measurement and correction of optical systems using wavefront analysis
US6271915B1 (en) Objective measurement and correction of optical systems using wavefront analysis
US6578963B2 (en) Wavefront sensor for objective measurement of an optical system and associated methods
EP1210003B1 (en) Objective measurement and correction of optical systems using wavefront analysis
MXPA00004897A (en) Objective measurement and correction of optical systems using wavefront analysis

Legal Events

Date Code Title Description
AS Assignment

Owner name: ALCON, INC., SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:ALCON UNIVERSAL, LTD.;REEL/FRAME:016855/0565

Effective date: 20011221

AS Assignment

Owner name: ALCON REFRACTIVEHORIZONS, INC., TEXAS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ALCON, INC.;REEL/FRAME:016877/0654

Effective date: 20050926

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION