Búsqueda Imágenes Maps Play YouTube Noticias Gmail Drive Más »
Iniciar sesión
Usuarios de lectores de pantalla: deben hacer clic en este enlace para utilizar el modo de accesibilidad. Este modo tiene las mismas funciones esenciales pero funciona mejor con el lector.

Patentes

  1. Búsqueda avanzada de patentes
Número de publicaciónUS20040143342 A1
Tipo de publicaciónSolicitud
Número de solicitudUS 10/345,666
Fecha de publicación22 Jul 2004
Fecha de presentación16 Ene 2003
Fecha de prioridad16 Ene 2003
También publicado comoEP1585458A1, US8029455, US9358145, US20090177215, US20120004590, US20150051533, US20160250055, WO2004064680A1
Número de publicación10345666, 345666, US 2004/0143342 A1, US 2004/143342 A1, US 20040143342 A1, US 20040143342A1, US 2004143342 A1, US 2004143342A1, US-A1-20040143342, US-A1-2004143342, US2004/0143342A1, US2004/143342A1, US20040143342 A1, US20040143342A1, US2004143342 A1, US2004143342A1
InventoresRichard Stack, William Athas, Richard Glenn, Dan Balbierz, John Lunsford, Michael Williams
Cesionario originalStack Richard S., Athas William L., Glenn Richard A., Dan Balbierz, John Lunsford, Williams Michael S.
Exportar citaBiBTeX, EndNote, RefMan
Enlaces externos: USPTO, Cesión de USPTO, Espacenet
Satiation pouches and methods of use
US 20040143342 A1
Resumen
A pouch positionable within the gastro-esophageal region of a patient, such as for use as a satiation device, is described herein. The pouch includes a proximal opening and an exit port, and is positionable such that food ingested by the patient passes into the interior of the pouch and subsequently out the exit port. A barrier on the proximal portion of the pouch contacts surrounding tissue and thereby minimizes passage of food from the esophagus around the exterior of the pouch—thereby substantially preventing food from bypassing the pouch. In preferred forms of the embodiment, the barrier is adaptable in response to movement of the surrounding tissue to maintain contact between the barrier and the surrounding tissue.
Imágenes(10)
Previous page
Next page
Reclamaciones(42)
We claim:
1. A method of positioning a prosthetic device within a patient having an esophagus, a stomach, and a gastro-esophageal junction region, the method comprising the steps of:
providing a prosthetic device having a proximal opening and an exit port, and a barrier on a proximal portion of the prosthetic device, the barrier having a central passage at least partially aligned with the proximal opening;
securing the prosthetic device within a patient by attaching the prosthetic device to tissue of the gastro-esophageal region of the patient, the prosthetic device oriented such that food ingested by the patient passes from the esophagus through the central passage and proximal opening into the interior of the prosthetic device; and
causing the barrier device to contact surrounding tissue, the barrier minimizing passage of food from the esophagus around the exterior of the prosthetic device and into the stomach.
2. The method of claim 1, wherein the barrier includes flexible webbing defining the central passage.
3. The method of claim 2, wherein the flexible webbing includes a resilient spring structure, and wherein the causing step includes allowing the spring structure to move radially outwardly, carrying the webbing into contact with the surrounding tissue.
4. The method of claim 1, wherein the barrier includes a plurality of spring members defining the central passage and spring biased in a radially outward direction, and wherein the causing step includes allowing the blade members to move radially outwardly into contact with the surrounding tissue.
5. The method of claim 1, wherein the barrier includes a stent structure spring biased in a radially outward direction, and wherein the causing step includes allowing the stent structure to move radially outwardly into contact with the surrounding tissue.
6. The method of claim 1, wherein the barrier includes a conformable material, and wherein the causing step includes positioning the conformable material into contact with surrounding tissue.
7. The method of claim 6, wherein the conformable material includes an inflatable bladder.
8. The method of claim 7, wherein the causing step includes inflating the bladder into contact with the surrounding tissue.
9. The method of claim 7, wherein the causing step includes inflating the bladder and then positioning the bladder into contact with the surrounding tissue.
10. The method of claim 6, wherein the conformable material is a foam material.
11. The method of claim 1, wherein the barrier includes a proximal rim formed on the prosthetic device, the rim having an inverted position extending within the prosthetic device and a non-inverted position, wherein
the securing step includes, with the rim in the inverted position, connecting a portion of the rim to the tissue; and
the causing step includes moving the rim to the non-inverted position.
12. The method of claim 1, wherein the method includes causing the barrier to maintain contact with the surrounding tissue during movement of the stomach or expansion of the prosthetic device.
13. The method of claim 1, wherein the prosthetic device is a satiation pouch, and wherein the proximal opening is larger than the exit port.
14. A medical device positionable within a gastro-esophageal junction region of a patient having an esophagus and a stomach, the medical device comprising:
a prosthetic device having a proximal opening and an exit port, a proximal portion of the prosthetic device positionable within the gastro-esophageal junction region such that the proximal opening is in substantial alignment with the esophagus; and
a barrier attached to a proximal portion of the prosthetic device, the barrier defining a central passage at least partially aligned with the proximal opening of the prosthetic device, the barrier positioned to contact surrounding tissue substantially around its circumference when the prosthetic device is positioned within the gastro-esophageal junction region and to substantially maintain said contact despite movement of the surrounding tissue.
15. The medical device of claim 14, wherein the barrier includes a wall of flexible webbing.
16. The medical device of claim 15, wherein the wall further includes a resilient spring structure connected to the flexible webbing.
17. The medical device of claim 14, wherein the barrier includes a plurality of spring members defining the central passage and spring biased in a radially outward direction.
18. The medical device of claim 14, wherein the barrier includes a stent structure spring biased in a radially outward direction.
19. The medical device of claim 14, wherein the barrier is a conformable structure.
20. The medical device of claim 19, wherein the conformable structure is an inflatable bladder.
21. The medical device of claim 19, wherein the conformable structure includes foam material.
22. The medical device of claim 14, wherein the barrier includes a proximal rim formed on the prosthetic device and anchors attached to the rim, the rim moveable between an inverted position in which the rim extends within the interior of the prosthetic device and in which the anchors are in first position, and a non-inverted position in which the rim is removed from the interior of the proximal device and in which the anchors are in a second position, the second position being more distal than the first position.
23. The medical device of claim 14, wherein the barrier is adaptable in response to movement of the surrounding tissue to maintain said contact between the barrier and the surrounding tissue.
24. A method of treating obesity in a patient having an esophagus, a stomach, and a gastro-esophageal junction region, the method comprising the steps of:
providing a pouch having a proximal opening and an exit port, the exit port being smaller than the proximal opening;
further providing a barrier having a central passage at least partially aligned with the proximal opening;
attaching the pouch to tissue of the gastro-esophageal region of the patient and causing the barrier device to contact tissue substantially around its circumference;
causing the patient to ingest food, the ingested food passing from the esophagus through the central passage and proximal opening into the interior of the pouch, the barrier minimizing passage of food from the esophagus around the exterior of the pouch.
25. The method of claim 24, wherein the barrier includes flexible webbing defining the central passage.
26. The method of claim 25, wherein the flexible webbing includes a resilient spring structure, and wherein the causing step includes allowing the spring structure to move radially outwardly, carrying the webbing into contact with the surrounding tissue.
27. The method of claim 24, wherein the barrier includes a plurality of spring members defining the central passage and spring biased in a radially outward direction, and wherein the attaching step includes allowing the blade members to move radially outwardly into contact with the surrounding tissue.
28. The method of claim 24, wherein the barrier includes a stent structure spring biased in a radially outward direction, and wherein the attaching step includes allowing the stent structure to move radially outwardly into contact with the surrounding tissue.
29. The method of claim 24, wherein the barrier includes a conformable material, and wherein the attaching step includes positioning the conformable material into contact with surrounding tissue.
30. The method of claim 29, wherein the conformable material includes an inflatable bladder.
31. The method of claim 30, wherein the attaching step includes inflating the bladder into contact with the surrounding tissue.
32. The method of claim 30, wherein the attaching step includes inflating the bladder and then positioning the bladder into contact with the surrounding tissue.
33. The method of claim 29, wherein the conformable material is a foam material.
34. The method of claim 24, wherein the barrier includes a proximal rim formed on the prosthetic device, the rim having an inverted position extending within the prosthetic device and a non-inverted position, wherein:
the attaching step includes, with the rim in the inverted position, connecting a portion of the rim to the tissue, and then moving the rim to the non-inverted position.
35. The method of claim 24, wherein the method includes causing the barrier to maintain contact with the surrounding tissue during movement of the stomach or expansion of the pouch.
36. A method of positioning a prosthetic device in a body cavity region defined by a circumferential wall, comprising the steps of:
providing a prosthetic device having a proximal opening and a distal opening, a passage extending between the proximal and distal openings, and a barrier on a proximal portion of the prosthetic device;
distending a circumferential wall of a body cavity region;
positioning the prosthetic device adjacent to the disentended circumferential wall; and
releasing the circumferential wall from the distended positioning, allowing the released wall to circumferentially contact the barrier, the barrier encouraging passage of substances through the passage by minimizing passage of body fluid around an exterior of the prosthetic device.
37. The method of claim 36, wherein the circumferential wall is flared from a proximal portion to a distal portion.
38. The method of claim 36, further comprising the step of attaching the prosthetic device to the circumferential wall using an attachment device.
39. The method of claim 37, wherein the circumferential wall is a wall of a proximal stomach, and wherein the barrier encourages passage of ingested food from an esophagus through the passage of the prosthetic device.
40. A method of positioning a prosthetic device in a body cavity region defined by a flared circumferential wall, comprising the steps of:
providing a prosthetic device having a proximal opening and a distal opening, a passage extending between the proximal and distal openings, and a barrier on a proximal portion of the prosthetic device;
positioning the barrier in a collapsed position;
positioning the prosthetic device with the barrier adjacent to the flared circumferential wall; and
releasing the barrier from the collapsed positioning, allowing the released barrier to circumferentially contact the flared circumferential wall, the barrier encouraging passage of substances through the passage by minimizing passage of body fluid around an exterior of the prosthetic device.
41. The method of claim 40, further comprising the step of attaching the prosthetic device to the circumferential wall using an attachment device.
42. The method of claim 40, wherein the circumferential wall is a wall of a proximal stomach, and wherein the barrier encourages passage of ingested food from an esophagus through the passage of the prosthetic device.
Descripción
    FIELD OF THE INVENTION
  • [0001]
    The present invention relates generally to the field of devices and methods for achieving weight loss in humans, and specifically to the use of devices implantable within the human stomach for controlling feelings of hunger and/or limiting food intake.
  • BACKGROUND OF THE INVENTION
  • [0002]
    An anatomical view of a human stomach S and associated features is shown in FIG. 1A. The esophagus E delivers food from the mouth to the proximal portion of the stomach S. The z-line or gastro-esophageal junction Z is the irregularly-shaped border between the thin tissue of the esophagus and the thicker tissue of the stomach wall. The gastro-esophageal junction region G is the region encompassing the distal portion of the esophagus E, the z-line, and the proximal portion of the stomach S.
  • [0003]
    Stomach S includes a fundus F at its proximal end and an antrum A at its distal end. Antrum A feeds into the pylorus P which attaches to the duodenum D, the proximal region of the small intestine. Within the pylorus P is a sphincter that prevents backflow of food from the duodenum D into the stomach. The middle region of the small intestine, positioned distally of the duodenum D, is the jejunum J.
  • [0004]
    Prosthetic devices for use in controlling obesity are shown and described in U.S. application Ser. No. 09/940,110, filed Aug. 27, 2001 and U.S. application Ser. No. 10/118,289 filed Apr. 8, 2002, and U.S. Provisional Application No. 60/379,306 filed May 10, 2002. These applications are owned by the assignee of the present application, and the disclosures of these applications are incorporated herein by reference. Certain forms of these devices involve positioning a prosthetic pouch in the proximal stomach as shown in FIG. 1B. The pouch 2 includes a proximal opening 4 and a smaller distal opening 6 and forms a small reservoir that collects masticated food from the esophagus—thereby limiting the amount of food that can be consumed at one time. As the pouch fills with food, it may distend, imparting pressure against the upper stomach and lower esophageal sphincter causing the patient to experience sensations of fullness. The pouch may additionally or alternatively act as a restrictor, limiting the amount of food intake. The pouch is fixed in place using clips, sutures, suitable adhesives or other means 8 at anchor points around the perimeter of the proximal opening 4.
  • [0005]
    Because of the flexible nature of the tissue of the gastro-esophageal junction region and/or the material forming the pouch, gaps 9 can occur along the perimeter of the pouch in regions between neighboring anchor points. Solving this problem is made more difficult by the flared geometry of the walls of the proximal stomach. Food entering or accumulating in the pouch 2 can ooze from these gaps and pass around the exterior of the pouch directly into the stomach, thereby decreasing the effectiveness of the prosthesis. The embodiments described herein optimize the function of the pouch devices by forming a barrier against passage of food through any such gaps and/or by eliminating such gaps.
  • SUMMARY OF THE INVENTION
  • [0006]
    The present invention includes a prosthetic device positionable within the gastro-esophageal junction region of a patient, wherein the prosthetic device includes a proximal opening and a barrier device defining a central passage at least partially aligned with the proximal opening of the prosthetic device. In a method for positioning the prosthetic device, the prosthetic device is attached to tissue of the gastro-esophageal region of the patient, with the device positioned such that food ingested by the patient passes from the esophagus through the central passage and proximal opening into the interior of the prosthetic device. The barrier contacts surrounding tissue and thereby minimizes passage of food from the esophagus around the exterior of the prosthetic device. In preferred forms of the embodiment, the barrier is adaptable in response to movement of the surrounding tissue to maintain contact between the barrier and the surrounding tissue.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0007]
    [0007]FIG. 1A is a schematic illustration of a human stomach and a portion of the small intestine.
  • [0008]
    [0008]FIG. 1B is a perspective view of a satiation pouch provided without supplemental barrier features. The pouch is shown positioned in the stomach.
  • [0009]
    [0009]FIG. 1C is a top plan view of the satiation pouch of FIG. 1B shown within the stomach, and illustrating formation of gaps around the perimeter of the proximal opening.
  • [0010]
    [0010]FIG. 2 is a perspective view of a first embodiment of a pouch having a circumferential barrier. The pouch is shown positioned in the stomach.
  • [0011]
    [0011]FIG. 3 is a perspective view similar to FIG. 2 showing expansion of the barrier into contact with tissue in a stomach having relatively broad proximal dimensions.
  • [0012]
    [0012]FIG. 4A is a top view of a pouch similar to the pouch of FIG. 2 showing the barrier and spring members restrained in a radially inward orientation.
  • [0013]
    [0013]FIG. 4B is a side elevation view of the pouch of FIG. 4A.
  • [0014]
    [0014]FIG. 5 is a perspective view similar to FIG. 2 showing a second embodiment having an alternative barrier configuration utilizing blade members.
  • [0015]
    [0015]FIG. 6 is a perspective view similar to FIG. 2 showing a third embodiment having yet another barrier configuration utilizing a band of stent material.
  • [0016]
    [0016]FIG. 7 is a perspective view similar to FIG. 2 showing a fourth embodiment having yet another barrier configuration utilizing leaf springs.
  • [0017]
    [0017]FIG. 8A is a cross-sectional side elevation view of a fifth embodiment of a pouch, which has a proximal rim that forms a circumferential seal with adjacent body tissue.
  • [0018]
    [0018]FIGS. 8B and 8C are cross-sectional side elevation views similar to FIG. 8A showing slight modifications to the rim position.
  • [0019]
    [0019]FIG. 9A is a side elevation view of the pouch of FIG. 8A, showing the rim in the inverted position.
  • [0020]
    [0020]FIG. 9B is a side elevation view similar to FIG. 9B, showing the rim moved to the non-inverted position and drawing tissue over a portion of the rim.
  • [0021]
    [0021]FIG. 10A is a side elevation view of an alternative to the pouch of FIG. 9A, showing the rim in an everted position.
  • [0022]
    [0022]FIG. 10B is a side elevation view similar to FIG. 10B, showing the rim moved to the non-everted position and drawing tissue inside a portion of the rim.
  • [0023]
    [0023]FIG. 11 is a schematic illustration showing a sixth embodiment of a pouch, which utilizes a bellows structure to create a barrier.
  • [0024]
    [0024]FIG. 12 is a schematic illustration showing a seventh embodiment of a pouch, which utilizes a conformable sealing ring.
  • [0025]
    [0025]FIG. 13 is a schematic illustration showing an eighth embodiment of a pouch, which utilizes an inflatable sealing ring.
  • [0026]
    [0026]FIG. 14 is a schematic illustration showing a ninth embodiment of a pouch having an expandable barrier stent.
  • [0027]
    [0027]FIG. 15 is a schematic illustration shown a tenth embodiment of a pouch showing an alternative configuration of a barrier stent.
  • DETAILED DESCRIPTION OF THE DRAWINGS
  • [0028]
    The drawings show a number of embodiments of satiation pouches having features that create a barrier against passage of food through gaps occurring between the upper perimeter of the pouch and adjacent tissue and/or that minimize or eliminate such gaps. Ideally, the barriers will form a seal with the adjacent tissue, however it is sufficient that the barriers prevent a substantial amount of food from passing between the exterior of the pouch and adjacent tissue, without necessarily forming an impermeable seal.
  • [0029]
    For the purposes of this application, the term “satiation devices” or “satiation pouches” will be used to mean devices or pouches intended to induce weight loss in one or more of a variety of ways. These include, but are not limited to, physically restricting the amount of food that can be consumed, and/or imparting pressure against portions of the body (e.g. stomach, esophagus, esophageal sphincter, etc) causing the patient to experience sensations of fullness, and/or affecting levels of hormones or other substances in the body that control or affect feelings of hunger, and/or affecting the amount of ingested food absorbed by the body.
  • [0030]
    The pouch of each described embodiment may be formed of a flexible material that will prevent passage of food through the sides of the pouch. Examples of such materials include, but are not limited to polyesters (e.g. Dacron® polyester), ePTFE fabric (e.g. GoreTex® fabric or others), a polyurethane such as ChronoFlex® polyurethane, nylon fabrics, silicone, other polymeric materials, and bio-absorbable materials (e.g. PLLA, PGA, PCL, poly-amhydride etc). The material may be a composite of compliant, semi-compliant and/or non-compliant materials that give different regions of the pouch different degrees of compliance so as to allow/limit expansion of the pouch in various locations. For example, it may be desirable to provide the pouch with a fairly elastic exit port to as to prevent occlusion in the event a large piece of food is ingested and/or to control the exit pressure of food from the pouch, whereas the proximal end of the pouch may be stiffer to prevent bulging. Varying degrees of compliance may also be built into the pouch by varying the cross-sectional thickness in different regions of the pouch. The material may be coated with a lubricious, bio-compatible, chemically inert material, such as paraleyne, to reduce friction on the base material's surface which will help prevent sticking and food build up on the device. The flexible pouch material may be reinforced with, constructed of, or supported by supporting members, such as a soft mesh, a cage structure, ribs, rings etc. The supporting members may be formed of stainless steel, polymer, shape memory materials such as nitinol, shape memory alloys, or shape memory polymers, or thickened regions of material. The pouch may be constructed so as to be self-expanding, such that the pouch springs radially open into an expanded condition upon ejection from a deployment device or catheter.
  • [0031]
    Implantation of the described devices is preferably performed endoscopically, by passing the devices through the esophagus, preferably under endoscopic visualization. Alternatively, the devices may be implanted using surgical or laparoscopic procedures.
  • [0032]
    During implantation the pouch is secured at the gastro-esophageal junction region G using sutures, clips, adhesives, stents or stent-like structures, or other suitable means. One suture attachment device found useful for applying sutures between the pouch and tissue is the “Sew-Right” suturing device available from LSI Solutions of Victor, N.Y. Although the pouch may be secured to the esophageal tissue, it is more preferable to apply sutures/clips below the Z-line to allow for attachment to the thicker tissue of the stomach wall.
  • [0033]
    Each of the described pouches includes a proximal opening and a distal exit port (see openings 4 and 6, respectively, of FIG. 1B). Because of its small volume (which may be on the order of approximately 2 cc-300 cc in volume, but is preferably in the range of 10-30 cc), the pouch functions to limit the amount of food that can be consumed at one time. Over time the food within this reservoir descends into the stomach through the exit port.
  • [0034]
    First Embodiment
  • [0035]
    [0035]FIGS. 2 and 3 show a first embodiment of a pouch 10 having a proximal opening 12, distal exit port or opening 14 and a passage extending between the proximal and distal openings.
  • [0036]
    A resilient ring 16 surrounds the proximal opening 12 and a plurality of spring members 18 are attached to the ring 16. Spring members 18 are preferably biased in a radially outward direction and can pivot relative to ring 16. Although spring members 18 are preferably moveable independently of one another, they may take the form of multiple fingers formed along a single length of wire.
  • [0037]
    Anchor loops 20 are positioned on the spring members 18. The anchor loops 20 serve to receive sutures, clips or other attachment devices used to connect the pouch to surrounding tissue. The loops in each of the embodiments described in this application should be considered optional, since the pouch may alternatively be anchored directly to the tissue without the use of the loops 20.
  • [0038]
    The anchor loops 20 may be positioned in the outer apexes of the spring members as shown, and/or they may be positioned elsewhere such as closer to the ring 16. See, for example, loops 20 a shown in dashed lines in FIG. 2. Ring 16, spring members 18 and loops 20 are preferably made of a resilient material (e.g. stainless steel, polymers etc.) suitable for use within the body.
  • [0039]
    Webbing 22 is connected to the spring members 18 along the circumference of the ring 16 to form a skirt-like member having a central opening. Webbing 22 is preferably formed of a flexible material that is substantially impermeable to masticated food. The material may be inelastic or elastic. Examples of suitable materials for the webbing 22 include those listed above for use with the pouch. When the pouch is secured within a patient, the webbing forms a barrier against passage of food between the pouch and surrounding tissue, and directs food into the proximal opening of the pouch. The webbing 22 and spring members 18 are preferably configured to form a dynamic seal with the surrounding tissue, so as to maintain a substantially consistent barrier despite stomach movement and flexure of the pouch. For example, the webbing 22 may be made expandable by using an elastic material and/or by including pleats in the webbing that allow for expansion. Also, the spring members 18 are preferably independently moveable and thus contribute to the dynamic nature of the barrier. In one variation on the first embodiment, the ring 16 and/or spring members 18 may be eliminated and the material of the webbing 22 itself may provide the necessary spring properties. In such an example, both the pouch and webbing, or the webbing along, may be formed of a resilient silicone or other resilient material.
  • [0040]
    During use, pouch 10 is introduced into the stomach S via the esophagus E and is held in the desired attachment location in the gastro-esophageal junction region. The pouch is anchored in place such as by connecting sutures or other attachment means to plurality of the anchor loops 20/20 a or directly to the pouch and/or webbing to secure the pouch 10 in position. The outward radial forces of spring members 18 cause the spring members 18 to extend radially outwardly, carrying the webbing 22 into contact with the surrounding tissue, creating a barrier that minimizes passage of food around the pouch. If required by the anatomy of the patient's stomach, the spring members 18 will cause the webbing 22 to flare outwardly into contact with the surrounding tissue as shown in FIG. 3. Similarly, a narrower proximal stomach may restrict outward movement of the spring members 18 such that they angle the webbing in a slight inward direction.
  • [0041]
    If desired, the spring members 18 may be held in a laterally inward position as shown in FIGS. 4A and 4B during positioning of the pouch within the stomach. For example, temporary sutures 24 may be threaded through loops 20 and cinched to draw spring members 18 into the position shown in FIG. 4A. As illustrated in FIG. 4B, when drawn inwardly the spring members 18 and webbing 22 may have a relatively flat profile. The pouch may be anchored into position with the spring members 18 and pouch in the inward position, such as by attaching sutures to the loops 20 as described above, or by attaching sutures to additional anchor loops 26 that are separate from the spring members 18. Once the pouch has been sutured into place, temporary sutures 24 are snipped so as to release spring members 18, allowing the spring members 18 to carry the webbing into contact with the surrounding tissue.
  • [0042]
    Second Embodiment
  • [0043]
    A second embodiment of a pouch 30 is shown in FIG. 5. The second embodiment differs from the first embodiment primarily in that a plurality of blades 32 are mounted to resilient ring 34. Blades 32 may be formed of a variety of materials, including those listed above for forming the pouch. The blades are outwardly biased using wire reinforcements or other biasing structure. Anchors 36 are preferably positioned in spaced-apart locations between the blades 32. The pouch 30 is sutured in place by attaching sutures between anchors 36 and adjacent tissue. The blades 32 spring outwardly into contact with surrounding tissue, thereby creating a seal or barrier against passage of food that might otherwise pass between gaps forming between anchor points.
  • [0044]
    Third Embodiment
  • [0045]
    [0045]FIG. 6 shows a third embodiment of a pouch 40, which uses an expandable stent-like band 42 for creating a seal or barrier. Band 42 is outwardly biased and may be formed of self-expanding material, such as stainless steel or a shape memory material such as nitinol or shape-memory polymer, and may be formed as a soft mesh or other framework formed of such materials in combination. The mesh may be created to have sufficiently small spaces between strands to form an effective barrier against a substantial portion of the ingested food, or it may be provided with a polymeric barrier that prevents ingested food from passing through the walls of the band 42. For example, the polymeric barrier may be a skin. formed on the exterior or interior of the mesh, or the mesh may be encapsulated in polymeric material or the polymer may be disposed in the interstices of the mesh.
  • [0046]
    During use, the pouch 40 is secured in place by attaching sutures between anchors 44 and adjacent tissue of the gastro-esophageal junction region. Band 42 then expands into contact with the surround tissue to form the seal or barrier. The band 42 is preferably positioned beyond the lower esophageal sphincter (identified as LES in FIG. 6) to avoid interference with proper sphincter function.
  • [0047]
    Fourth Embodiment
  • [0048]
    A fourth embodiment of a pouch 50, shown in FIG. 7, is similar to the previously described embodiments except that a plurality of leaf springs 52 are attached at the proximal end of the pouch. Springs 52 are outwardly biased to create the seal or barrier with surrounding tissue. As with prior embodiments, the pouch may include a resilient ring 54, and the pouch may be attached to surrounding tissue using sutures passed through anchors 56. In an alternative configuration, springs 52 may be coil springs which may be connected to a common structure at their proximal ends, -or which may have free proximal ends.
  • [0049]
    Fifth Embodiment
  • [0050]
    Referring to FIG. 8A, a fifth embodiment of a pouch 60 includes an enlarged rim 62 surrounding the proximal opening 64 of the pouch 60. Rim 62 may extend slightly outwardly from the external surface of the pouch as shown in FIG. 8A, or slightly inwardly as shown in FIG. 8B, or both as shown in FIG. 8C. In one form of the fifth embodiment, anchor loops 66 extend from a distal portion of the rim 62 as shown in FIG. 8A. Before the pouch 60 is fixed within the body, the rim 62 is inverted inside the pouch 60 to the position shown in FIG. 9A. Once the rim has been inverted, anchor loops 66 extend in a proximal direction as shown. The pouch 60 is inserted into the stomach and the anchor loops 66 are secured to tissue using sutures or other attachment means. Next, the rim 62 is returned to the non-inverted position shown in FIG. 9B, causing the anchor loops 66 to return to the distally-oriented position. The loops 66 pull the attached tissue in a distal direction, around the edges of the rim 62, creating a taut and leak-resistant seal around the rim.
  • [0051]
    In another form of the fifth embodiment, anchors 66 extend distally on an interior portion of the rim as shown in FIG. 8B. According to this form of the embodiment, before the pouch is fixed within the body, the rim 62 is everted outside the pouch 60 to the position shown in FIG. 10A—causing anchor loops 66 to extend in a proximal direction as shown. The pouch 60 is inserted into the stomach and the anchor loops 66 are secured to tissue using sutures or other attachment means. Next, the rim 62 is returned to the non-everted position shown in FIG. 10B, causing the anchor loops 66 to return to the distally-oriented position. The loops 66 pull the attached tissue in a distal direction, inside the edges of the rim 62, again creating a seal around the rim.
  • [0052]
    Sixth through Eighth Embodiments
  • [0053]
    [0053]FIG. 11 shows a sixth embodiment of a pouch 70, which includes an expandable bellows structure 72, attached to a resilient ring 74. Bellows structure 72 includes a central channel 76 in alignment with the proximal opening (not shown) of the pouch 70, and is preferably formed of a flexible material that is substantially impervious to masticated food, and may be formed of materials similar to those listed for use in constructing the pouch. It may have a substantially cylindrical shape or a tapered geometry such as that shown in FIG. 11. At the proximal end of the bellows structure 72, surrounding the central channel 76, is a sealing ring 78 formed of a flexible material capable of forming a seal when urged into contact with body tissue.
  • [0054]
    Anchors 79 are attached to resilient ring 74 and are used to receive sutures, clips, etc that will connect the pouch to surrounding body tissue. Once the pouch has been fixed within the stomach, the bellows structure 72 expands the sealing ring 78 into contact with surrounding tissue, thereby creating a barrier or seal. As with prior embodiments, the resilience of the bellows allows the seal to be maintained despite movement of the stomach or expansion of the pouch.
  • [0055]
    Similar embodiments are shown in FIGS. 12 and 13. In the seventh embodiment of FIG. 12, the proximal portion of the pouch 80 includes a conformable sealing ring 82 made of foam, sponge, silicone, or other conformable material that will seal against surrounding tissue when pressed into contact with the tissue. Ring 82 includes a central channel 84 and may include a cylindrical or tapered geometry. Anchors 86 receive sutures or clips used to fix the pouch to body tissue.
  • [0056]
    The eighth embodiment of FIG. 13 is a pouch 90 having a conformable sealing ring 92. Sealing ring 92 is formed of an elastic or inelastic bladder inflatable using an inflation fluid or gas. The bladder may be inflated prior to insertion into the stomach, or it may include a detachable inflation valve (not shown) that may be used to introduce inflation medium into the bladder after the pouch has been fixed within the stomach. As with the seventh embodiment, the sealing ring 92 may have a cylindrical or tapered geometry. Ingested food flows through a central channel 94 in the sealing ring 92 and into the pouch 90.
  • [0057]
    Ninth and Tenth Embodiments
  • [0058]
    [0058]FIGS. 14 and 15 show ninth and tenth embodiments, respectively, of pouches having barrier devices for minimizing passage of food around, rather than through, the pouch. These embodiments are similar to the FIG. 6 embodiment in that they utilize a stent-like structure to expand against surrounding tissue to create the barrier or seal.
  • [0059]
    The barrier provided with the pouch 100 of FIG. 14 differs from that of FIG. 6 in that band 102 of stent material extends further into the esophagus, creating a seal with the tissue of the esophagus. This seal may be above, below, or within the lower esophageal sphincter (LES). As with each of the prior embodiments, anchors 104 receive sutures or clips that are used to fix the device to tissue in the region.
  • [0060]
    In the tenth embodiment shown in FIG. 15, a flexible tubular member 114 extends between the band 112 of stent material and the pouch 110. During use, member 114 may be positioned within the LES region while still preserving function of the LES.
  • [0061]
    Various embodiments of satiation devices have been described herein. These embodiments are given by way of example and are not intended to limit the scope of the present invention. It should be appreciated, moreover, that the various features of the embodiments that have been described may be combined in various ways to produce numerous additional embodiments. Also, while various materials, dimensions, shapes, implantation locations, etc. have been described for use with disclosed embodiments, others besides those disclosed may be utilized without exceeding the scope of the invention. Lastly, while the pouches have been described for use in controlling feelings of hunger, the barrier devices described herein may be equally suitable for use with other prosthetic devices positionable within the body, including prosthetic valves implanted in the lower esophagus or proximal stomach for controlling gastro-esophageal reflux disease (GERD).
Citas de patentes
Patente citada Fecha de presentación Fecha de publicación Solicitante Título
US20190 *11 May 1858 Dressing and sizing warps
US21796 *12 Oct 1858WmMethod of
US99439 *1 Feb 1870 Improved harvester-gearing for changing speed
US4246893 *5 Jul 197827 Ene 1981Daniel BersonInflatable gastric device for treating obesity
US4315509 *16 Oct 197816 Feb 1982Smit Julie AInsertion and removal catheters and intestinal tubes for restricting absorption
US4403604 *13 May 198213 Sep 1983Wilkinson Lawrence HGastric pouch
US4416267 *10 Dic 198122 Nov 1983Garren Lloyd RMethod and apparatus for treating obesity
US4441215 *23 Feb 198310 Abr 1984Kaster Robert LVascular graft
US4607618 *11 Ene 198526 Ago 1986Angelchik Jean PMethod for treatment of morbid obesity
US4641653 *19 Feb 198510 Feb 1987Rockey Arthur GMedical sleeve
US4648383 *22 Jul 198510 Mar 1987Angelchik Jean PPeroral apparatus for morbid obesity treatment
US4694827 *14 Ene 198622 Sep 1987Weiner Brian CInflatable gastric device for treating obesity and method of using the same
US4723547 *7 May 19859 Feb 1988C. R. Bard, Inc.Anti-obesity balloon placement system
US4846836 *3 Oct 198811 Jul 1989Reich Jonathan DArtificial lower gastrointestinal valve
US4899747 *6 Sep 198313 Feb 1990Garren Lloyd RMethod and appartus for treating obesity
US5163952 *14 Sep 199017 Nov 1992Michael FroixExpandable polymeric stent with memory and delivery apparatus and method
US5211658 *5 Nov 199118 May 1993New England Deaconess Hospital CorporationMethod and device for performing endovascular repair of aneurysms
US5234454 *5 Ago 199110 Ago 1993Akron City HospitalPercutaneous intragastric balloon catheter and method for controlling body weight therewith
US5246456 *8 Jun 199221 Sep 1993Wilkinson Lawrence HFenestrated gastric pouch
US5259399 *2 Mar 19929 Nov 1993Alan BrownDevice and method of causing weight loss using removable variable volume intragastric bladder
US5290217 *10 Oct 19911 Mar 1994Earl K. SipesMethod and apparatus for hernia repair
US5306300 *22 Sep 199226 Abr 1994Berry H LeeTubular digestive screen
US5314473 *5 Ene 199324 May 1994Godin Norman JProsthesis for preventing gastric reflux into the esophagus
US5327914 *2 Sep 199212 Jul 1994Shlain Leonard MMethod and devices for use in surgical gastroplastic procedure
US5345949 *20 Ago 199313 Sep 1994Shlain Leonard MMethods for use in surgical gastroplastic procedure
US5405377 *21 Feb 199211 Abr 1995Endotech Ltd.Intraluminal stent
US5514176 *20 Ene 19957 May 1996Vance Products Inc.Pull apart coil stent
US5593434 *7 Jun 199514 Ene 1997Advanced Cardiovascular Systems, Inc.Stent capable of attachment within a body lumen
US5653743 *9 Sep 19945 Ago 1997Martin; Eric C.Hypogastric artery bifurcation graft and method of implantation
US5662713 *14 Sep 19952 Sep 1997Boston Scientific CorporationMedical stents for body lumens exhibiting peristaltic motion
US5674241 *15 Jul 19967 Oct 1997Menlo Care, Inc.Covered expanding mesh stent
US5709657 *4 Ago 199320 Ene 1998Zimmon Science CorporationMethods for placement of balloon tamponade devices
US5720776 *7 Jun 199524 Feb 1998Cook IncorporatedBarb and expandable transluminal graft prosthesis for repair of aneurysm
US5749918 *20 Jul 199512 May 1998Endotex Interventional Systems, Inc.Intraluminal graft and method for inserting the same
US5771903 *22 Sep 199530 Jun 1998Kirk Promotions LimitedSurgical method for reducing the food intake of a patient
US5820584 *28 Ago 199713 Oct 1998Crabb; Jerry A.Duodenal insert and method of use
US5855601 *21 Jun 19965 Ene 1999The Trustees Of Columbia University In The City Of New YorkArtificial heart valve and method and device for implanting the same
US5861036 *28 Feb 199619 Ene 1999Biomedix S.A. SwitzerlandMedical prosthesis for preventing gastric reflux in the esophagus
US5868141 *14 May 19979 Feb 1999Ellias; Yakub A.Endoscopic stomach insert for treating obesity and method for use
US5887594 *22 Sep 199730 Mar 1999Beth Israel Deaconess Medical Center Inc.Methods and devices for gastroesophageal reflux reduction
US5922019 *29 Dic 199513 Jul 1999Schneider (Europe) A.G.Conical stent
US5993483 *18 Dic 199730 Nov 1999Schneider (Usa) IncStent and method of manufacturing same
US6102922 *29 Jun 199815 Ago 2000Kirk Promotions LimitedSurgical method and device for reducing the food intake of patient
US6113609 *26 May 19985 Sep 2000Scimed Life Systems, Inc.Implantable tissue fastener and system for treating gastroesophageal reflux disease
US6146416 *2 Sep 199714 Nov 2000Boston Scientific CorporationMedical stents for body lumens exhibiting peristaltic motion
US6159238 *19 May 199912 Dic 2000Scimed Life Systems, IncStent having variable properties and method of its use
US6254642 *9 Dic 19973 Jul 2001Thomas V. TaylorPerorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US6258120 *23 Dic 199710 Jul 2001Embol-X, Inc.Implantable cerebral protection device and methods of use
US6264700 *27 Ago 199824 Jul 2001Endonetics, Inc.Prosthetic gastroesophageal valve
US6302917 *31 Ago 199916 Oct 2001Wilson-Cook Medical IncorporatedAnti-reflux esophageal prosthesis
US6503264 *3 Mar 20007 Ene 2003Bioenterics CorporationEndoscopic device for removing an intragastric balloon
US6540789 *10 Nov 20001 Abr 2003Scimed Life Systems, Inc.Method for treating morbid obesity
US6544291 *26 Mar 20018 Abr 2003Thomas V. TaylorSutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof
US6547801 *14 Sep 199915 Abr 2003Sofradim ProductionGastric constriction device
US6558400 *30 May 20016 May 2003Satiety, Inc.Obesity treatment tools and methods
US6558429 *26 Mar 20016 May 2003Reflux CorporationPerorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US6572627 *8 Ene 20013 Jun 2003Shlomo GabbaySystem to inhibit and/or control expansion of anatomical features
US6572629 *15 Ago 20013 Jun 2003Johns Hopkins UniversityGastric reduction endoscopy
US6596023 *7 Jul 200022 Jul 2003Meadox Medicals, Inc.Shaped woven tubular soft-tissue prostheses and method of manufacturing the same
US6663639 *7 Mar 200016 Dic 2003Ndo Surgical, Inc.Methods and devices for tissue reconfiguration
US6740121 *25 Ene 200225 May 2004Boston Scientific CorporationIntragastric stent for duodenum bypass
US6764518 *12 Jun 200220 Jul 2004Biomedix S.A.Prosthesis for controlling the direction of flow in a duct of a living organism
US6960233 *9 Dic 20031 Nov 2005Torax Medical, Inc.Methods and apparatus for improving the function of biological passages
US7220284 *29 Jun 200522 May 2007Valentx, Inc.Gastrointestinal sleeve device and methods for treatment of morbid obesity
US20010011543 *4 Ene 20019 Ago 2001Peter ForsellControlled food flow in a patient
US20020055757 *23 Mar 20019 May 2002Torre Roger De LaMethod and device for use in minimally invasive placement of intragastric devices
US20040092892 *31 Oct 200313 May 2004Jonathan KaganApparatus and methods for treatment of morbid obesity
US20040107004 *9 Ene 20033 Jun 2004Seedling Enterprises, LlcBariatric sleeve
US20050256587 *9 May 200317 Nov 2005Egan Thomas DGastric bypass prosthesis
Citada por
Patente citante Fecha de presentación Fecha de publicación Solicitante Título
US706694517 May 200227 Jun 2006Wilson-Cook Medical Inc.Intragastric device for treating obesity
US708708826 Abr 20028 Ago 2006Torax Medical, Inc.Methods and apparatus for regulating the flow of matter through body tubing
US722028429 Jun 200522 May 2007Valentx, Inc.Gastrointestinal sleeve device and methods for treatment of morbid obesity
US722327726 Ago 200429 May 2007Delegge RebeccaMethod of inducing satiety
US731448920 Ago 20031 Ene 2008Ethicon Endo-Surgery, Inc.Method and apparatus to facilitate nutritional malabsorption
US766618020 May 200523 Feb 2010Tyco Healthcare Group LpGastric restrictor assembly and method of use
US767806813 Dic 200516 Mar 2010Gi Dynamics, Inc.Atraumatic delivery devices
US768233026 Jul 200623 Mar 2010Gi Dynamics, Inc.Intestinal sleeve
US769105320 May 20056 Abr 2010Tyco Healthcare Group LpGastric restrictor assembly and method of use
US76954277 Jun 200513 Abr 2010Torax Medical, Inc.Methods and apparatus for treating body tissue sphincters and the like
US769544613 Dic 200513 Abr 2010Gi Dynamics, Inc.Methods of treatment using a bariatric sleeve
US770818121 Mar 20084 May 2010Barosense, Inc.Endoscopic stapling devices and methods
US772193221 Mar 200825 May 2010Barosense, Inc.Endoscopic stapling devices and methods
US775853511 Dic 200720 Jul 2010Gi Dynamics, Inc.Bariatric sleeve delivery devices
US77668612 Oct 20063 Ago 2010Gi Dynamics, Inc.Anti-obesity devices
US7771382 *11 Ene 200610 Ago 2010Gi Dynamics, Inc.Resistive anti-obesity devices
US779444730 Jul 200414 Sep 2010Valentx, Inc.Gastrointestinal sleeve device and methods for treatment of morbid obesity
US78155891 Jun 200419 Oct 2010Gi Dynamics, Inc.Methods and apparatus for anchoring within the gastrointestinal tract
US781559116 Sep 200519 Oct 2010Gi Dynamics, Inc.Atraumatic gastrointestinal anchor
US78332808 Abr 200816 Nov 2010Barosense, Inc.Satiation devices and methods
US783764314 Feb 200523 Nov 2010Gi Dynamics, Inc.Methods and devices for placing a gastrointestinal sleeve
US78376697 Abr 200623 Nov 2010Valentx, Inc.Devices and methods for endolumenal gastrointestinal bypass
US78461388 May 20067 Dic 2010Valentx, Inc.Cuff and sleeve system for gastrointestinal bypass
US788179725 Abr 20071 Feb 2011Valentx, Inc.Methods and devices for gastrointestinal stimulation
US788352421 Dic 20078 Feb 2011Wilson-Cook Medical Inc.Method of delivering an intragastric device for treating obesity
US78922149 May 200622 Feb 2011Valentx, Inc.Attachment system for transmural attachment at the gastroesophageal junction
US789229230 Jun 200622 Feb 2011Synecor, LlcPositioning tools and methods for implanting medical devices
US790921921 Mar 200822 Mar 2011Barosense, Inc.Endoscopic stapling devices and methods
US790922221 Mar 200822 Mar 2011Barosense, Inc.Endoscopic stapling devices and methods
US790922321 Mar 200822 Mar 2011Barosense, Inc.Endoscopic stapling devices and methods
US791389221 Mar 200829 Mar 2011Barosense, Inc.Endoscopic stapling devices and methods
US792206221 Mar 200812 Abr 2011Barosense, Inc.Endoscopic stapling devices and methods
US793463110 Nov 20083 May 2011Barosense, Inc.Multi-fire stapling systems and methods for delivering arrays of staples
US793507329 Oct 20073 May 2011Gi Dynamics, Inc.Methods of treatment using a bariatric sleeve
US79678188 Jun 200628 Jun 2011Cook Medical Technologies LlcCautery catheter
US79764888 Jun 200512 Jul 2011Gi Dynamics, Inc.Gastrointestinal anchor compliance
US7981162 *5 Ene 200419 Jul 2011Barosense, Inc.Satiation devices and methods
US79811638 Ene 201019 Jul 2011Gi Dynamics, Inc.Intestinal sleeve
US800750710 May 200730 Ago 2011Cook Medical Technologies LlcIntragastric bag apparatus and method of delivery for treating obesity
US80121358 May 20066 Sep 2011Valentx, Inc.Attachment cuff for gastrointestinal implant
US80121409 May 20066 Sep 2011Valentx, Inc.Methods of transmural attachment in the gastrointestinal system
US801685127 Dic 200713 Sep 2011Cook Medical Technologies LlcDelivery system and method of delivery for treating obesity
US802074118 Mar 200820 Sep 2011Barosense, Inc.Endoscopic stapling devices and methods
US80294555 Mar 20094 Oct 2011Barosense, Inc.Satiation pouches and methods of use
US805742020 Dic 200715 Nov 2011Gi Dynamics, Inc.Gastrointestinal implant with drawstring
US80707435 May 20056 Dic 2011Valentx, Inc.Devices and methods for attaching an endolumenal gastrointestinal implant
US810093129 Oct 201024 Ene 2012Bfkw, LlcBariatric device and method
US8109895 *31 Ago 20077 Feb 2012Barosense, Inc.Intestinal sleeves and associated deployment systems and methods
US811401017 Feb 201014 Feb 2012Tyco Healthcare Group LpGastric restrictor assembly and method of use
US811877425 Sep 200721 Feb 2012Valentx, Inc.Toposcopic access and delivery devices
US813730126 May 200920 Mar 2012Gi Dynamics, Inc.Bariatric sleeve
US816287126 May 200924 Abr 2012Gi Dynamics, Inc.Bariatric sleeve
US81824419 Jun 200822 May 2012Valentx, Inc.Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US818245911 Oct 200622 May 2012Valentx, Inc.Devices and methods for endolumenal gastrointestinal bypass
US81871642 Nov 200929 May 2012Torax Medical, Inc.Methods and apparatus for treating body tissue sphincters and the like
US820645623 May 200626 Jun 2012Barosense, Inc.Restrictive and/or obstructive implant system for inducing weight loss
US82111861 Abr 20103 Jul 2012Metamodix, Inc.Modular gastrointestinal prostheses
US821626821 Dic 200610 Jul 2012Cook Medical Technologies LlcIntragastric bag for treating obesity
US824120222 Abr 201014 Ago 2012Barosense, Inc.Restrictive and/or obstructive implant for inducing weight loss
US826788822 Jul 201018 Sep 2012Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US82825989 Jul 20109 Oct 2012Metamodix, Inc.External anchoring configurations for modular gastrointestinal prostheses
US830366913 Sep 20106 Nov 2012Gi Dynamics, Inc.Methods and apparatus for anchoring within the gastrointestinal tract
US83375664 Dic 200925 Dic 2012Barosense, Inc.Method and apparatus for modifying the exit orifice of a satiation pouch
US84254512 Jun 201123 Abr 2013Gi Dynamics, Inc.Gastrointestinal anchor compliance
US843520320 Jun 20077 May 2013Covidien LpGastric restrictor assembly and method of use
US846997721 May 201025 Jun 2013Barosense, Inc.Endoscopic plication device and method
US84861538 Dic 200616 Jul 2013Gi Dynamics, Inc.Anti-obesity devices
US852943111 Ago 200910 Sep 2013Bfkw, LlcBariatric device and method
US85684881 Oct 200929 Oct 2013Boston Scientific Scimed, Inc.Satiation devices and methods
US862858314 Sep 201214 Ene 2014Gi Dynamics, Inc.Methods and apparatus for anchoring within the gastrointestinal tract
US867283120 Dic 201118 Mar 2014Bfkw, LlcBariatric device and method
US87026417 Ene 201122 Abr 2014Metamodix, Inc.Gastrointestinal prostheses having partial bypass configurations
US87026426 Ago 201222 Abr 2014Metamodix, Inc.External anchoring configurations for modular gastrointestinal prostheses
US874742118 Abr 201110 Jun 2014Boston Scientific Scimed, Inc.Multi-fire stapling systems and methods for delivering arrays of staples
US87712194 Oct 20118 Jul 2014Gi Dynamics, Inc.Gastrointestinal implant with drawstring
US878435422 Feb 201122 Jul 2014Boston Scientific Scimed, Inc.Positioning tools and methods for implanting medical devices
US87845008 Oct 200422 Jul 2014Boston Scientific Scimed, Inc.Devices and methods for retaining a gastro-esophageal implant
US879029029 Abr 201329 Jul 2014Covidien LpGastric restrictor assembly and method of use
US880159927 Dic 201312 Ago 2014Bfkw, LlcBariatric device and method
US880164721 Feb 200812 Ago 2014Gi Dynamics, Inc.Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
US880827025 Sep 200719 Ago 2014Valentx, Inc.Methods for toposcopic sleeve delivery
US883440528 Jun 201116 Sep 2014Gi Dynamics, Inc.Intestinal sleeve
US884567322 Jul 201030 Sep 2014Tulip Medical Ltd.Bioerodible self-deployable intragastric implants and methods for use thereof
US884575330 Sep 201330 Sep 2014Boston Scientific Scimed, Inc.Satiation devices and methods
US885849622 Jul 201014 Oct 2014Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US886400821 Mar 201121 Oct 2014Boston Scientific Scimed, Inc.Endoscopic stapling devices and methods
US886478422 Jul 201021 Oct 2014Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US886484012 Oct 201121 Oct 2014Apollo Endosurgery, Inc.Intragastric implants with collapsible frames
US88708062 May 201128 Oct 2014Gi Dynamics, Inc.Methods of treatment using a bariatric sleeve
US88709664 Oct 201228 Oct 2014Apollo Endosurgery, Inc.Intragastric balloon for treating obesity
US888269827 Mar 201211 Nov 2014Gi Dynamics, Inc.Anti-obesity devices
US889467013 Ago 200925 Nov 2014Bfkw, LlcMucosal capture fixation of medical device
US892044712 Oct 201130 Dic 2014Apollo Endosurgery, Inc.Articulated gastric implant clip
US89451671 Sep 20113 Feb 2015Boston Scientific Scimed, Inc.Gastric space occupier systems and methods of use
US895631831 May 201217 Feb 2015Valentx, Inc.Devices and methods for gastrointestinal bypass
US895638018 Oct 201117 Feb 2015Apollo Endosurgery, Inc.Reactive intragastric implant devices
US89615394 May 200924 Feb 2015Boston Scientific Scimed, Inc.Endoscopic implant system and method
US89682705 Dic 20113 Mar 2015Valentx, Inc.Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment
US8992457 *14 Jul 201131 Mar 2015Boston Scientific Scimed, Inc.Gastrointestinal implants
US903964931 May 201226 May 2015Valentx, Inc.Devices and methods for gastrointestinal bypass
US90443003 Abr 20142 Jun 2015Metamodix, Inc.Gastrointestinal prostheses
US905016831 May 20129 Jun 2015Valentx, Inc.Devices and methods for gastrointestinal bypass
US90559423 Oct 200616 Jun 2015Boston Scienctific Scimed, Inc.Endoscopic plication devices and methods
US905599824 Jul 201216 Jun 2015Bfkw, LlcBariatric device and method for recipient with altered anatomy
US906084431 Oct 200323 Jun 2015Valentx, Inc.Apparatus and methods for treatment of morbid obesity
US908466910 Dic 201321 Jul 2015Gi Dynamics, Inc.Methods and apparatus for anchoring within the gastrointestinal tract
US90954163 Jun 20144 Ago 2015Gi Dynamics, Inc.Removal and repositioning devices
US910772722 Ene 201418 Ago 2015Boston Scientific Scimed, Inc.Satiation devices and methods
US913834025 Ago 201422 Sep 2015Boston Scientific Scimed, Inc.Gastro-esophageal implants
US915560921 Feb 201213 Oct 2015Gi Dynamics, Inc.Bariatric sleeve
US917375931 May 20123 Nov 2015Valentx, Inc.Devices and methods for gastrointestinal bypass
US917376030 Sep 20123 Nov 2015Metamodix, Inc.Delivery devices and methods for gastrointestinal implants
US91800353 Jun 201010 Nov 2015Boston Scientific Scimed, Inc.Devices and methods for retaining a gastro-esophageal implant
US918003616 Jun 201410 Nov 2015Boston Scientific Scimed, Inc.Methods for implanting medical devices
US919878925 Jun 20141 Dic 2015Bfkw, LlcBariatric device and method
US9198790 *17 Oct 20111 Dic 2015Apollo Endosurgery, Inc.Upper stomach gastric implants
US923794416 Jun 201419 Ene 2016Gi Dynamics, Inc.Intestinal sleeve
US924803815 May 20142 Feb 2016Boston Scientific Scimed, Inc.Methods for retaining a gastro-esophageal implant
US92542144 Ene 20139 Feb 2016Boston Scientific Scimed, Inc.Satiation devices and methods
US927801928 Ene 20128 Mar 2016Metamodix, IncAnchors and methods for intestinal bypass sleeves
US927802016 Oct 20148 Mar 2016Gi Dynamics, Inc.Methods of treatment using a bariatric sleeve
US931436114 Sep 200719 Abr 2016Boston Scientific Scimed, Inc.System and method for anchoring stomach implant
US9358144 *4 Feb 20157 Jun 2016Boston Scientific Scimed, Inc.Gastrointestinal implants
US937533818 May 201228 Jun 2016Bfkw, LlcIntraluminal device and method with enhanced anti-migration
US939896914 May 201226 Jul 2016Apollo Endosurgery, Inc.Upper stomach gastric implants
US941494822 Oct 201516 Ago 2016Bfkw, LlcBariatric device and method
US9445791 *8 Jun 201220 Sep 2016Boston Scientific Scimed, Inc.Systems and methods related to gastro-esophageal implants
US945195623 Abr 201427 Sep 2016Boston Scientific Scimed, Inc.Multi-fire stapling systems
US945196016 Ene 201327 Sep 2016Valentx, Inc.Devices and methods for gastrointestinal bypass
US9456825 *11 Feb 20134 Oct 2016Boston Scientific Scimed, Inc.Endoscopic implant system and method
US946310712 Oct 201111 Oct 2016Apollo Endosurgery, Inc.Variable size intragastric implant devices
US949836517 Oct 201122 Nov 2016Apollo Endosurgery, Inc.Intragastric implants with multiple fluid chambers
US952664814 Mar 201427 Dic 2016Synerz Medical, Inc.Intragastric device for treating obesity
US953913328 Jun 201310 Ene 2017Apollo Endosurgery, Inc.Stomach-spanning gastric implants
US954524912 Ago 201317 Ene 2017Boston Scientific Scimed, Inc.Overtube introducer for use in endoscopic bariatric surgery
US95453265 Mar 201317 Ene 2017Bfkw, LlcIntraluminal device delivery technique
US956112712 Jun 20157 Feb 2017Valentx, Inc.Apparatus and methods for treatment of morbid obesity
US956618131 May 201214 Feb 2017Valentx, Inc.Devices and methods for gastrointestinal bypass
US958578313 May 20157 Mar 2017Gi Dynamics, Inc.Methods and apparatus for anchoring within the gastrointestinal tract
US96228973 Mar 201618 Abr 2017Metamodix, Inc.Pyloric anchors and methods for intestinal bypass sleeves
US963611416 Sep 20142 May 2017Boston Scientific Scimed, Inc.Endoscopic stapling devices
US96689019 Jul 20136 Jun 2017Apollo Endosurgery Us, Inc.Intragastric implants with duodenal anchors
US967548926 Jun 201413 Jun 2017Valentx, Inc.Devices and methods for gastrointestinal bypass
US968197421 Oct 201420 Jun 2017Apollo Endosurgery Us, Inc.Intragastric implants with collapsible frames
US968197517 May 201320 Jun 2017Valentx, Inc.Devices and methods for gastrointestinal bypass
US968733418 Ene 201227 Jun 2017Boston Scientific Scimed, Inc.Intestinal sleeves and associated deployment systems and methods
US97440618 Dic 201529 Ago 2017Gi Dynamics, Inc.Intestinal sleeve
US97505961 Sep 20155 Sep 2017Gi Dynamics, Inc.Bariatric sleeve
US975726413 Mar 201412 Sep 2017Valentx, Inc.Devices and methods for gastrointestinal bypass
US978898420 Jul 201517 Oct 2017Boston Scientific Scimed, Inc.Satiation devices and methods
US97954983 Oct 201324 Oct 2017Apollo Endosurgery Us, Inc.Intragastric balloon for treating obesity
US980174729 Ene 201531 Oct 2017Apollo Endosurgery Us, Inc.Non-inflatable gastric implants and systems
US20030018377 *26 Abr 200223 Ene 2003Berg Todd A.Methods and apparatus for regulating the flow of matter through body tubing
US20030078611 *17 May 200224 Abr 2003Kiyoshi HashibaIntragastric device for treating obesity
US20030199987 *21 May 200323 Oct 2003Torax Medical, Inc.Methods and apparatus for regulating the flow of matter through body tubing
US20030199991 *9 Jun 200323 Oct 2003Stack Richard S.Satiation devices and methods
US20040107004 *9 Ene 20033 Jun 2004Seedling Enterprises, LlcBariatric sleeve
US20040117031 *16 Ene 200317 Jun 2004Stack Richard S.Satiation devices and methods
US20040241768 *29 Mar 20042 Dic 2004Whitten David G.Fluorescent polymer-QTL approach to biosensing
US20050033345 *26 Ago 200410 Feb 2005Delegge RebeccaMethod of inducing satiety
US20050043817 *20 Ago 200324 Feb 2005Mckenna Robert HughMethod and apparatus to facilitate nutritional malabsorption
US20050085923 *2 Dic 200321 Abr 2005Gi Dynamics, Inc.Anti-obesity devices
US20050096750 *29 Nov 20045 May 2005Jonathan KaganApparatus and methods for treatment of morbid obesity
US20050125075 *1 Jun 20049 Jun 2005Gi Dynamics, Inc.Intestinal sleeve
US20050177181 *29 Dic 200411 Ago 2005Jonathan KaganDevices and methods for treating morbid obesity
US20050197715 *16 Feb 20058 Sep 2005Torax Medical, Inc.Methods and apparatus for implanting devices into non-sterile body lumens or organs
US20050240279 *29 Jun 200527 Oct 2005Jonathan KaganGastrointestinal sleeve device and methods for treatment of morbid obesity
US20050267499 *2 Ago 20051 Dic 2005Stack Richard SMethod and apparatus for modifying the exit orifice of a satiation pouch
US20050283235 *7 Jun 200522 Dic 2005Torax Medical, Inc.Methods and apparatus for treating body tissue sphincters and the like
US20060129027 *8 Dic 200515 Jun 2006Antonio CatonaDevice for treating obesity
US20060206063 *9 May 200614 Sep 2006Jonathan KaganAttachment system for transmural attachment at the gastroesophageal junction
US20060252983 *10 Feb 20069 Nov 2006Lembo Nicholas JDynamically adjustable gastric implants and methods of treating obesity using dynamically adjustable gastric implants
US20060264981 *20 May 200523 Nov 2006Viola Frank JGastric restrictor assembly and method of use
US20060264982 *20 May 200523 Nov 2006Viola Frank JGastric restrictor assembly and method of use
US20060264983 *20 May 200523 Nov 2006Henry HolstenGastric restrictor assembly and method of use
US20060276812 *3 Abr 20067 Dic 2006Hill James WDynamic reinforcement of the lower esophageal sphincter
US20060282107 *8 May 200614 Dic 2006Kiyoshi HashibaIntragastric device for treating obesity
US20060293759 *21 Jun 200628 Dic 2006Torax Medical, Inc.Methods and apparatus for regulating the flow of matter through body tubing
US20070010866 *8 May 200611 Ene 2007Mitchell DannAttachment cuff for gastrointestinal implant
US20070123994 *29 Nov 200531 May 2007Ethicon Endo-Surgery, Inc.Internally Placed Gastric Restriction Device
US20070219571 *3 Oct 200620 Sep 2007Balbierz Daniel JEndoscopic plication devices and methods
US20070239284 *21 Dic 200611 Oct 2007Skerven Gregory JCoiled intragastric member for treating obesity
US20070276428 *21 Dic 200629 Nov 2007Haller Frederick BIntragastric bag for treating obesity
US20080167610 *25 Sep 200710 Jul 2008Valentx, Inc.Toposcopic methods and devices for delivering a sleeve having axially compressed and elongate configurations
US20080167629 *25 Sep 200710 Jul 2008Valentx, Inc.Methods for toposcopic sleeve delivery
US20080208356 *18 Dic 200728 Ago 2008Stack Richard SSatiation devices and methods
US20080269797 *8 Abr 200830 Oct 2008Stack Richard SSatiation devices and methods
US20080281257 *10 May 200713 Nov 2008Waller David FIntragastric bag apparatus and method of delivery for treating obesity
US20080319470 *20 Jun 200725 Dic 2008Viola Frank JGastric restrictor assembly and method of use
US20090149871 *29 Dic 200411 Jun 2009Jonathan KaganDevices and methods for treating morbid obesity
US20090149879 *10 Dic 200711 Jun 2009Dillon Travis EDynamic volume displacement weight loss device
US20090164028 *21 Dic 200725 Jun 2009Wilson-Cook Medical Inc.Method of delivering an intragastric device for treating obesity
US20090171382 *27 Dic 20072 Jul 2009Wilson-Cook Medical Inc.Delivery system and method of delivery for treating obesity
US20090299487 *10 Ago 20093 Dic 2009Stack Richard SSatiation devices and methods
US20100076573 *2 Nov 200925 Mar 2010Kugler Chad JMethods and apparatus for treating body tissue sphincters and the like
US20100145472 *17 Feb 201010 Jun 2010Tyco Healthcare Group LpGastric Restrictor Assembly And Method Of Use
US20100198237 *13 Ago 20095 Ago 2010Sentinel Group, LlcMucosal capture fixation of medical device
US20100228272 *21 May 20109 Sep 2010Balbierz Daniel JEndoscopic plication device and method
US20110015665 *22 Jul 201020 Ene 2011Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US20110015666 *22 Jul 201020 Ene 2011Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US20110022072 *22 Jul 201027 Ene 2011Tulip Medical Ltd.Bioerodible self-deployable intragastric implants
US20110092879 *29 Oct 201021 Abr 2011Bfkw,LlcBariatric device and method
US20110264234 *21 Ago 200927 Oct 2011Sentinel Group, LlcGastro-esophageal reflux disease reduction device and method
US20110270410 *14 Jul 20113 Nov 2011Barosense, Inc.Satiation devices and methods
US20120095499 *17 Oct 201119 Abr 2012Allergan, Inc.Upper stomach gastric implants
US20120191213 *25 Jul 201126 Jul 2012Sentinel Group, LlcStress reduction device and method
US20120203061 *26 Oct 20109 Ago 2012Allergan, Inc.Bariatric device and method for weight loss
US20130012863 *8 Jun 201210 Ene 2013Barosense, Inc.Restrictive and/or obstructive implant system for inducing weight loss
US20130304094 *11 Feb 201314 Nov 2013Boston Scientific Scimed, Inc.Endoscopic implant system and method
US20150202039 *4 Feb 201523 Jul 2015Boston Scientific Scimed, Inc.Gastrointestinal implants
EP1669045A1 *9 Dic 200414 Jun 2006AMI Agency for Medical Innovations GmbHGastric band for the treatment of obesity
WO2005037152A18 Oct 200428 Abr 2005Synecor, LlcDevices and methods for retaining a gastro-esophageal implant
Clasificaciones
Clasificación de EE.UU.623/23.65, 623/23.67, 623/23.7
Clasificación internacionalA61F5/00
Clasificación cooperativaA61F5/0036, A61F5/0076, A61F5/0079
Clasificación europeaA61F5/00B6N
Eventos legales
FechaCódigoEventoDescripción
8 Sep 2003ASAssignment
Owner name: BAROSENSE, INC., CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:STACK, RICHARD S.;ATHAS, WILLIAM L.;GLENN, RICHARD A.;AND OTHERS;REEL/FRAME:014496/0717;SIGNING DATES FROM 20030722 TO 20030826
3 Feb 2005ASAssignment
Owner name: SYNECOR, LLC, NORTH CAROLINA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BAROSENSE, INC.;REEL/FRAME:015655/0224
Effective date: 20050111
29 Jun 2009ASAssignment
Owner name: BAROSENSE, INC., CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYNECOR LLC;REEL/FRAME:022878/0603
Effective date: 20090626
Owner name: BAROSENSE, INC.,CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYNECOR LLC;REEL/FRAME:022878/0603
Effective date: 20090626