US20040176816A1 - Lead connection module of a modular implantable medical device - Google Patents
Lead connection module of a modular implantable medical device Download PDFInfo
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- US20040176816A1 US20040176816A1 US10/730,878 US73087803A US2004176816A1 US 20040176816 A1 US20040176816 A1 US 20040176816A1 US 73087803 A US73087803 A US 73087803A US 2004176816 A1 US2004176816 A1 US 2004176816A1
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- overmold
- implantable medical
- medical device
- imd
- lead
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37514—Brain implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/37518—Anchoring of the implants, e.g. fixation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3752—Details of casing-lead connections
- A61N1/3754—Feedthroughs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3758—Packaging of the components within the casing
Definitions
- the invention relates to medical devices, and more particularly, to implantable medical devices that deliver therapy to and/or monitor a patient.
- implantable medical devices may include a variety of electrical and/or mechanical components.
- an IMD includes a rigid housing that houses all of its components, which are generally fragile, to protect the components from forces to which they would otherwise be exposed when implanted within the human body.
- IMD housings are typically hermetically sealed.
- Many IMD housings are fabricated from Titanium because of its desirable rigidity and biocompatibility.
- the size and shape of an IMD housing is dependant on the sizes and shapes of the components of the IMD.
- Large components common to most IMDs include a battery, a telemetry coil, and a hybrid circuit that includes digital circuits, e.g., integrated circuit chips and/or a microprocessor, and analog circuit components.
- Digital circuits e.g., integrated circuit chips and/or a microprocessor, and analog circuit components.
- Attempts have been made to reduce the size of the IMD housing by reducing the size of these components, changing the shape of these components, and organizing these components within the IMD housing to avoid empty space within the housing.
- the size, shape and rigidity of IMD housings still greatly limits the locations within the human body where an IMD can be practically implanted.
- an IMD is typically implanted within the abdomen, upper pectoral region, or interclavicular region of a patient.
- Leads or catheters must be used in order to deliver therapy or monitor a physiological parameter at a location of the body other than where the IMD is implanted.
- Implantation and positioning of leads and catheters can be difficult and time-consuming from the perspective of a surgeon, particularly where the IMD is located a significant distance from the treatment or monitoring site.
- the increased surgical time, increased surgical trauma, and increased amount of implanted material associated with the use of leads and catheters can increase the risk to the patient of complications associated with the implantation of an IMD.
- IMDs that are used to treat or monitor the brain are implanted some distance away from the brain, e.g., within the interclavicular region of patients.
- DBS deep brain stimulation
- the long leads that connect the implantable medical device to electrodes implanted within the brain require tunneling under the scalp and the skin of the neck, thereby requiring increased surgery and a prolonged amount of time under general anesthesia during the implant procedure.
- the lengthy tract along the leads is more susceptible to infection, and the leads can erode the overlying scalp, forcing removal so that the scalp can heal.
- the long leads running under the scalp and through the neck are more susceptible to fracture due to torsional and other forces caused by normal head and neck movements.
- the invention relates to a lead connection module of a modular implantable medical device.
- various functional components of the IMD are separated into individual interconnected modules.
- This modular architecture for the implantable medical device permits the device footprint to be distributed over a larger area while making the profile smaller.
- the multiple modules and their respective flexible interconnections may permit the overall shape of the implantable medical device to be formed to better match the body location into which it is to be implanted.
- the component modules within the IMD are coupled to one or more leads that are deployed within a patient's body.
- External leads are used to electrically connect the external locations to a control module within the implantable medical device, and the control module can monitor the electrical activity, or regulate administration of therapy, or both. Accordingly, it is desirable for the external leads be both electronically and mechanically coupled to the implantable medical device.
- the present invention provides such a coupling of the external leads to the implantable medical device.
- the invention is directed to a an implantable medical device that includes at least two interconnected modules, each of the modules comprising a housing, and an overmold that at least partially encapsulates each of the housings.
- the overmold comprises a lead connection module that is configured to accept an external lead.
- the invention supports an overmold made of multiple materials, such as elastomeric and non-elastomeric materials.
- the invention is directed to an overmold for a modular implantable medical device.
- the overmold comprises a first material configured to hold at least part of a module, a second material coupled to the first material, and a lead connection module configured to accept an external lead, the lead connection module being deployed within the overmold.
- FIGS. 1A and IB are diagrams illustrating use of an implantable medical device in a patient according to an example embodiment of the present invention.
- FIG. 2 is a schematic diagram illustrating an implantable medical device according to an embodiment of the present invention.
- FIG. 3A and 3B are schematic diagrams illustrating an implantable medical device according to another embodiment of the present invention.
- FIGS. 4A-4F are schematic diagrams illustrating various orientations of multiple modules within an implantable medical device according to various embodiments of the present invention.
- FIG. 5A is a schematic diagram illustrating the construction of an overmold and modules used in construction of an implantable medical device according to the present invention.
- FIG. 5B is an exploded view of an embodiment of the overmold and modules shown in FIG. 5A.
- FIG. 5C is a side view of an embodiment of the overmold and modules shown in FIG. 5A.
- FIGS. 6A-6B are schematic diagrams illustrating an example embodiment of a multi-module implantable medical device having multiple interconnect sites according to the present invention.
- FIGS. 7A-7B are schematic diagrams illustrating an example embodiment of a multi-module implantable medical device having tethered interconnect sites according to the present invention.
- FIG. 7C is a perspective view of a multi-module implantable medical device such as that depicted in FIGS. 7A and 7B.
- FIGS. 8A-8B are schematic diagrams illustrating the interaction of components of an implantable medical device that are part of an overmold according to the present invention.
- FIGS. 9A-9B are schematic diagrams illustrating an electronic module of a multi-module implantable medical device having a connection leads according to the present invention.
- FIGS. 1A and 1B are diagrams illustrating use of an implantable medical device (IMD) in a patient according to an example embodiment of the present invention.
- IMD implantable medical device
- An IMD 101 is implanted within a patient 100 in order to permit IMD 101 to provide therapies to the patient 100 .
- IMD 11 is implanted under the scalp of the patient 100 in order to locate the device 101 as close as possible to the location of leads 102 that provide the therapy.
- FIG. 1A shows patient 100 with IMD 101 deployed beneath his scalp.
- IMD 101 is a neurostimulator that provides deep brain stimulation via leads 102 deployed in the brain of patient 100 .
- IMD 101 is deployed in proximity to site of stimulation therapy.
- IMD 101 may be used to treat any nervous system disorder including, but not limited to, epilepsy, pain, psychological disorders including mood and anxiety disorders, movement disorders (MVD) such as, but not limited to, essential tremor and Parkinson's disease and neurodegenerative disorders.
- MMD movement disorders
- IMD 101 is depicted as a neurostimulator, the invention is not limited to applications in which the IMD is a neurostimulator.
- the invention may be employed with IMDs that perform any monitoring or therapeutic functions.
- the invention is not limited to IMDs that include leads deployed in the brain, but may also be employed with leads deployed anywhere in the head or neck including, for example, leads deployed on or near the surface of the skull, leads deployed beneath the skull such as near or on the dura mater, leads placed adjacent cranial or other nerves in the neck or head, or leads placed directly on the surface of the brain.
- the invention may be employed with IMDs coupled to any sensing or therapeutic elements, such as temperature sensors or motion sensors.
- the invention may also be employed with different types of IMDs including, but not limited to, IMDs operating in an open loop mode (also referred to as non-responsive operation), IMDs operating in a closed loop mode (also referred to as responsive), and IMDs for providing monitoring and/or warning.
- IMDs operating in an open loop mode also referred to as non-responsive operation
- IMDs operating in a closed loop mode also referred to as responsive
- IMDs for providing monitoring and/or warning for providing monitoring and/or warning.
- IMD 101 has a low profile, i.e., IMD 101 is thin to permit the IMD 101 to be deployed effectively, comfortably and cosmetically and under the scalp.
- IMD 101 has a maximum thickness of between approximately 4 millimeters and approximately 8 millimeters. The use of a reduced profile may reduce the risk of infection, skin erosion and cosmetic issued related to the implantation of IMD 101 .
- IMD 101 may be deployed proximate to a treatment or monitoring site.
- IMD 101 While the embodiment of IMD 101 shown in FIGS. 1A-1B is implanted under the scalp of patient 100 and may be used when the therapy provided to patient 100 includes neural stimulation of a brain, other embodiments of IMD 100 permit the device to be implanted at many other locations within the body.
- IMD 101 includes a plurality of interconnected modules. Each module generally perform assigned functions.
- IMD 101 includes three modules, namely, a control module 103 , a power supply module 104 and a recharge module 105 .
- Control module 103 typically includes the electronic components associated with the functions of IMD 101 .
- control module 103 may include a hybrid circuit that includes digital circuits such as integrated circuit chips and one or more microprocessors, and analog circuit components. Accordingly, control module 103 may also be referred to as an electronic module.
- Power supply module 104 typically comprises one or more energy storage devices, such as a rechargeable lithium ion battery.
- Recharge module 105 typically includes one or more coils for transmitting or receiving electromagnetic energy through the scalp.
- the transmitted energy may include energy to be stored in power supply module 104 .
- the transmitted energy may also include communication, such as information encoded in radio frequency transmissions.
- Individual modules 103 and 104 may be encased in biocompatible metal shields such as titanium shield halves, and may be sealed against contamination.
- individual modules 103 and 104 may include insulation to electrically isolate the electrical components inside the modules from the metal shields.
- the modules are coupled to an overmold 106 which may be made of a biocompatible material.
- Overmold herein is not intend to limit the invention to embodiments in which the overmold is a molded structure. Overmold may be a molded structure, or may be a structure formed by any process.
- overmold 106 encases all modules 103 , 104 and 105 .
- overmold 106 is disposed over or around the modules without encasing the modules.
- overmold 106 acts as a “frame” to hold the modules in a fixed position relative to one another, but does not fully cover the modules.
- FIG. 2 is a schematic diagram illustrating an IMD according to another embodiment of the present invention.
- the IMD 201 is arranged in a triangular configuration, and includes three modules: a control module 210 , a power supply module 211 , and a recharge module 212 .
- Overmold 214 at least partially covers the housings of control module 210 and power source supply module 211 , and also at least partially covers recharge module 212 .
- These three modules are physically connected together to construct IMD 201 , and any modules may also be electrically coupled to one another.
- IMD 201 also includes two lead connection modules 213 A, 213 B for accepting an external lead.
- overmold 214 includes lead connection modules 213 A, 213 B, and lead connection modules 213 A, 213 B need not be fixedly coupled to any module 210 , 211 or 212 .
- Lead connection modules 213 A, 213 B contain a set of lead connection modules that permits external leads to be connected to the IMD 210 .
- lead connection modules 213 A, 213 B include one or more conductors that electrically couple the external leads to control module 210 .
- the triangular configuration of IMD 201 permits IMD 201 to possess a thin profile by spreading the modules over a larger surface area.
- the triangular shape also helps to keep the surface area compact.
- the structure of IMD 201 may also be curved to conform to the shape of the location within a patient in which the device is being implanted. For example, implantation of IMD 201 under the scalp of a patient may be accomplished if the overall shape of IMD 201 is curved to follow the shape of a patient's skull. Any number of shapes may be used to match a particular IMD 201 to an implantation location for a device.
- FIG. 3A and 3B are schematic diagrams illustrating an IMD according to yet another embodiment of the present invention.
- IMD 301 a flat device is shown that consists of multiple modules.
- This embodiment of IMD 310 may be used in other locations within a patient in which the implantation location does not require such an exact match between the device and physical structures of the patient such as bone or muscle.
- IMD 3 01 may provide a small profile when implanted as to not protrude excessively once implanted.
- the flat embodiment shown in FIGS. 3A-3B may represent a device that may be a pectoral implant that may be used to treat angina, to provide vagal nerve stimulation, or to provide cardiac rhythm management. Similar devices may be implanted into an upper buttock implant location, into an abdomen location, and into periphery. A device implanted into an upper buttock location may be useful in urological and gastrological implantation therapies. A device implanted into an abdomen location may be useful in providing pain, spasticity, and chemotherapy treatment. A device implanted into a periphery location may be useful in providing muscle stimulation, on-site nerve stimulation, and diaphragm stimulation therapies.
- IMD 301 comprises an overmold 302 that includes two lead connection modules 303 A, 303 B for accepting an external lead.
- lead connection modules 303 A, 303 B are depicted open to illustrate inclusion in overmold 302 .
- Additional alternate embodiments for implantable medical devices implemented according to principles of the present invention may also include non-electrical based therapies such as targeted introduction of fluids and similar therapeutic materials using pumps and reservoirs of material.
- non-electrical based therapies such as targeted introduction of fluids and similar therapeutic materials using pumps and reservoirs of material.
- FIGS. 4A-4F are schematic diagrams illustrating exemplary configurations and orientations of modules within IMD 401 A through 401 F (hereinafter 410 ), according to various embodiments of the present invention.
- IMD 401 consists of multiple modules that may be arranged into any number of orientations as shown in the various embodiments of FIGS. 4A-4F.
- each IMD 401 is depicted deployed proximate to the skull of a patient, with leads 402 A and 402 B deployed through burr holes 402 A and 402 B and coupled to IMD 401 .
- the leads are coupled to the IMD via lead connection modules 415 A and 415 B.
- the lead connection modules may assume a variety of orientations relative to other components of IMD 401 .
- IMD 401 has three modules as discussed above in reference to FIGS. 1 B and 2 : a control module 410 , a power source module 411 , and a recharge module 412 .
- An overmold 413 at least partially covers the housings of control module 410 and power source module 411 .
- the modules may be arranged into a number of orientations as long as any interconnections between the modules may be routed within the device.
- the various embodiments include triangular configurations, as is shown in FIGS. 4A-4C, or linear configurations as shown in FIGS. 4D-4F. In FIG. 4D, one of the three modules, such as the recharge module, is deployed as a tethered module 414 rather than being covered by overmold 413 .
- the invention is not limited to the deployments of the lead connection modules shown in FIGS. 4A-4F.
- the lead connection modules may be located on various positions within IMD 401 .
- Lead connection modules may be oriented, for example, to permit the leads to be routed to lead locations in an efficient manner or to support management of excess lead length. Any number of other orientations and alternate embodiments may be constructed according to principles of the present invention and consistent with the claims recited herein.
- FIGS. 5A-5C are schematic diagrams illustrating an exemplary construction of an overmold used in construction of an IMD according to the present invention.
- FIG. 5A illustrates that IMD 501 comprises a set of modules 510 - 512 , a set of motion restriction elements, such as motion restriction fibers 521 .
- motion restriction fibers 521 are coupled to modules 510 and 511 , and are covered at least in part by overmold 522 .
- Overmold 522 typically includes a solid biocompatible material.
- Overmold 522 may comprise an elastomeric material that is soft and flexible, such as silicone.
- overmold 522 may comprise a non-elastomeric material that imparts rigidity to IMD 501 .
- a non-elastomeric material in overmold 522 acts as a “frame” to hold the modules in a fixed position relative to one another, and does not fully cover the modules.
- Overmold 522 covers, at least in part, the components and modules within IMD 501 while providing a flexible structure that permits the device 501 to conform to fit each individual patient. Because overmnold 522 is typically flexible, IMD 501 may benefit from motion restriction devices such as motion restriction fibers 521 , which provide structural integrity to device 501 once implanted into the patient.
- FIG. 5B illustrates that the overmold 522 may include a non-elastomeric, or “hard” component 531 in addition to an elastomeric, or “soft” component 532 .
- the non-elastomeric component 531 is shaped to conform to the shape of at least one of modules 510 - 512 such that the modules may be restrained from motion by the non-elastomeric components.
- the non-elastomeric components 531 are typically made of a solid biocompatible material such as polysulfone, and may also be made of metal such as titanium.
- the non-elastomeric components 531 are utilized in locations in which motion is to be restricted. Any or all modules may be constrained by one or more hard components 531 .
- Overmold 522 including elastomeric and non-elastomeric components, can be fabricated into a single structure before the modules 510 - 512 are inserted into the device 501 .
- overmold 522 serves a number of functions.
- overmold 522 incorporates motion restriction elements within the device 501 , and attaches to modules and other elements to provide a unified device.
- overmold 522 provides a smooth interface surface for the device as it interacts with the patient, and protects electrical connections and feed through wires that connect modules to external leads.
- Overmold 522 may also include a durometric specific material to provide desired device qualities such as flexibility and structural integrity.
- the material used to construct overmold 522 may possess a thermal conductivity characteristic to either act as a heat sink, or act as an insulator to shield the patient 100 from any excess heat from IMD 501 . Because IMD 501 may be constructed from a large number of modules to perform a desired task, the materials selected for used in constructing the overmold 522 may vary as needed by each embodiment.
- FIG. 5C illustrates that overmold 522 provides sloped interface 541 between an exemplary module 542 within IMD 501 and the patient's body.
- sloped interface 541 provides a smooth transition and eases sharp edges that are known to cause possible points of stress for tissue.
- An angle of interface from the patient's body and the sloped interface 541 can be approximately 135 degrees.
- overmold 522 Additional details regarding the overmold 522 are described in co-pending and commonly assigned U.S. Patent Application entitled “OVERMOLD FOR A MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-332US01/P-11798.00.
- FIGS. 6A-6B are schematic diagrams illustrating an example embodiment of a multi-module IMD 601 having multiple interconnect sites according to the present invention.
- FIG. 6A shows a distributed IMD have multiple lead connection modules 613 that are located adjacent to each other while being near a control module 610 .
- FIG. 6B shows a distributed IMD have multiple lead connection modules 613 that are located on opposite sides of the control module 610 .
- lead connection modules are included in overmold 622 .
- the lead connection modules 613 provide a mechanism for electrically connecting electronics within control module 610 to one or more external leads 643 .
- the external leads provide an electrical signal path from a desired part of the patient's body to IMD 601 .
- FIG. 6A is used when it is desirable for the external leads 643 to follow similar signal path lengths from the control module 610 to the treatment or monitoring site of the body.
- the embodiment of FIG. 6B may be used in cases in which the external leads 643 are farther apart. Because the lead connection modules 613 provide electrical connections between the control module 610 and the external leads 643 , the lead connection modules 613 are typically located close to the control module 610 to reduce a length for electrical interconnections between them. Additional details regarding the interconnection of the control module 610 , the lead connection modules 613 , and the external leads 643 is discussed below in reference to FIGS. 8A-8B.
- FIGS. 7A-7B are schematic diagrams illustrating an example embodiment of a multi-module IMD having tethered interconnect sites according to the present invention.
- an overmold 722 of an IMD 701 may cover and connect a plurality of modules 710 - 712 while not covering lead connection modules 713 , which are part of a tethered interconnection housing 761 .
- tethered interconnection housing 761 is optional.
- the lead connection modules 713 that are used to connect external leads (not shown) to the device 701 are not contained within the overmold 722 . As such, the implantation of the device would not require the insertion of external leads into the 722 .
- the external leads may be located a distance away from the overall device 701 . Such an arrangement may assist in the management of the external leads as they are placed within the patient and routed to a lead location.
- overmold 722 may include mechanical structures such one or more grooves or a pouch to contain and route the external leads and aid lead management.
- An exemplary structure, a groove 750 is depicted in a perspective view of IMD 701 .
- external leads may possess an excess length that may be managed to reduce the risks of lead migration and lead damage.
- FIGS. 8A-8B are schematic diagrams illustrating an exemplary interaction of components of an IMD 801 .
- FIG. 8A provides a side view of an overmold 822 , which includes one or more soft or elastomeric components 832 and one or more hard or non-elastomeric components 831 , which interface with a control module 810 .
- Non-elastomeric component 831 may be shaped to mate with the module 810 to provide motion restriction for the module.
- Non-elastomeric component 831 may be mechanically connected to other modules using a motion restriction device (not shown).
- the overmold 822 covers all of these components in this embodiment.
- a through hole 851 may be located through the non-elastomeric component 831 and elastomeric component 832 to provide an attachment point for IMD 801 .
- IMD 801 may be anchored in place using bone screws or other anchoring devices.
- Through holes 851 permit IMD 801 to be mechanically anchored to the patient once the device 801 is positioned at a desired location.
- a bone screw inserted into through hole 851 would seat against non-elastomeric component 831 , but the invention encompasses embodiments in which a bone screw would seat against another component, such as control module 810 .
- FIG. 8B illustrates a top view of the device 801 having elastomeric component 832 of overmold 822 covering the non-elastomeric components 831 that frame control module 810 .
- the through hole 851 used as an attachment point is shown as part of non-elastomeric component 831 that is covered by elastomeric component 832 .
- the shape of non-elastomeric component 831 and control module 810 are shown as being rectangular in this embodiment. However, one skilled in the art will recognize that any shape for the non-elastomeric component 831 and control module 810 may be used without deviating from the spirit and scope of the present invention.
- a lead interconnect device 813 is included within the non-elastomeric components 831 of overmold 822 .
- the non-elastomeric component 831 restrains control module 810 and external leads 843 .
- the external leads have iso-diametric proximal ends for connection of the external leads 843 to IMD 801 .
- An external lead 843 is inserted into the lead connection module in order to connect the external leads 843 to electronics within control module 810 of IMD 801 .
- This electrical connection from the control module 810 to the external leads 843 is made using a module connection lead wire 846 that extends from control module 810 and physically connects with the external lead 843 within the lead connection module 813 .
- the lead connection module 813 may also include a mechanical lead securing mechanism 845 that engages the external lead 843 to restrain its motion and ensure electrical connection with feed-through wires 846 .
- a tool 847 is used to engage the mechanical lead securing mechanism 845 within the lead connection module 813 .
- the mechanical lead securing mechanism 845 comprises a mechanical set-screw that is tightened by a screwdriver.
- An example of such a mechanical lead securing mechanism 845 is a low-profile DBS lead extensions manufactured by Medtronic Inc.
- the mechanical lead securing mechanism 845 may be tool-less using a variety of known securing technologies that ensures the external lead 843 does not separate from the lead connection module 813 .
- Tool-assisted or tool-less coupling of leads to the IMD both allow medical personnel to couple leads to the IMD quickly and securely.
- FIGS. 9A-9B are schematic diagrams illustrating a control module of a multi-module IMD having a connection leads according to the present invention.
- FIG. 9A provides a prospective view of a control module 910 to illustrate a set of feed-through wires 946 that electrically couple electronics 950 within the control module 810 to external leads as discussed above in reference to FIGS. 8A and 8B.
- FIG. 9B provides a side view of the control module 910 of FIG. 9A to again illustrate the use of the feed-through wires 946 as discussed above.
Abstract
A modular implantable medical device includes two or more interconnected modules and an overmold that at least partially encapsulates each of the housings of the modules. The overmold also includes a lead connection module for accepting an external lead. The lead connection module electrically and mechanically couples the lead to the components of the implantable medical device.
Description
- This application claims the benefit of:
- 1. U.S. Provisional Application entitled “CRANIAL NEUROSTIMULATOR AND METHOD,” Ser. No. 60/431,854, (Attorney Docket No. P-10891.00), filed on Dec. 9, 2002;
- 2. U.S. Provisional Application entitled “Implantable Cranial Medical Devices and Methods,” Ser. No. 60/471,262, (Attorney Docket No. P-11462.00), filed on May 16, 2003;
- 3. U.S. Provisional Application entitled “IMPLANTABLE CRANIAL MEDICAL DEVICES AND METHODS,” Ser. No. 60/503,945, (Attorney Docket No. P-11696.00), filed on Sep. 20, 2003;
- 4. U.S. Provisional Application entitled “IMPLANTABLE CRANIAL MEDICAL DEVICES AND METHODS,” Ser. No. 60/503,946, (Attorney Docket No. P-11697.00), filed on Sep. 20, 2003; and
- 5. U.S. Provisional Application entitled “Thin Neuro Stimulation System, Device and Method,” Ser. No. 60/507,857, (Attorney Docket No. P-20211.00), filed on Oct. 1, 2003. The entire content of each of these U.S. Provisional Applications is incorporated herein by reference.
- The following co-pending and commonly-assigned U.S. Patent Applications, filed on even date herewith, are also incorporated herein by reference in their entirety:
- 1. U.S. Patent Application entitled “MODULAR IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-318US01/P-10891.00;
- 2. U.S. Patent Application entitled “IMPLANTATION OF LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” to Ruchika Singhal et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-330US01/P-11795.00;
- 3. U.S. Patent Application entitled “COUPLING MODULE OF A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Darren A. Janzig et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-331US01/P-11796.00;
- 4. U.S. Patent Application entitled “OVERMOLD FOR A MODULAR IMPLANTABLE MEDICAL DEVICE,” to Ruchika Singhal et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-332US01/P-11798.00;
- 5. U.S. Patent Application entitled “REDUCING RELATIVE INTER-MODULE MOTION IN A DISTRIBUTED MODULAR IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-333US01/P-11797.00;
- 6. U.S. Patent Application entitled “LOW-PROFILE IMPLANTABLE MEDICAL DEVICE,” to Darren A. Janzig et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-335US01/P-11801.00; and
- 7. U.S. Patent Application entitled “CONCAVITY OF AN IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: 1023-336US01/P-11800.00.
- 8. U.S. Patent Application entitled “MODULAR IMPLANTABLE MEDICAL DEVICE,” to Carl D. Wahlstrand et al., filed Dec. 9, 2003, assigned Attorney Docket No.: P-20542.00.
- The invention relates to medical devices, and more particularly, to implantable medical devices that deliver therapy to and/or monitor a patient.
- Depending on the application for which they are implanted in a patient, implantable medical devices (IMDs) may include a variety of electrical and/or mechanical components. Typically, an IMD includes a rigid housing that houses all of its components, which are generally fragile, to protect the components from forces to which they would otherwise be exposed when implanted within the human body. In order to avoid potentially harmful interactions between the components and bodily fluids, e.g., corrosion, IMD housings are typically hermetically sealed. Many IMD housings are fabricated from Titanium because of its desirable rigidity and biocompatibility.
- The size and shape of an IMD housing is dependant on the sizes and shapes of the components of the IMD. Large components common to most IMDs include a battery, a telemetry coil, and a hybrid circuit that includes digital circuits, e.g., integrated circuit chips and/or a microprocessor, and analog circuit components. Attempts have been made to reduce the size of the IMD housing by reducing the size of these components, changing the shape of these components, and organizing these components within the IMD housing to avoid empty space within the housing. Despite these efforts to reduce the size of IMD housings, the size, shape and rigidity of IMD housings still greatly limits the locations within the human body where an IMD can be practically implanted.
- Due to these limitations, an IMD is typically implanted within the abdomen, upper pectoral region, or interclavicular region of a patient. Leads or catheters must be used in order to deliver therapy or monitor a physiological parameter at a location of the body other than where the IMD is implanted. Implantation and positioning of leads and catheters can be difficult and time-consuming from the perspective of a surgeon, particularly where the IMD is located a significant distance from the treatment or monitoring site. Moreover, the increased surgical time, increased surgical trauma, and increased amount of implanted material associated with the use of leads and catheters can increase the risk to the patient of complications associated with the implantation of an IMD.
- For example, IMDs that are used to treat or monitor the brain, e.g., to deliver deep brain stimulation (DBS) therapy, are implanted some distance away from the brain, e.g., within the interclavicular region of patients. The long leads that connect the implantable medical device to electrodes implanted within the brain require tunneling under the scalp and the skin of the neck, thereby requiring increased surgery and a prolonged amount of time under general anesthesia during the implant procedure. The lengthy tract along the leads is more susceptible to infection, and the leads can erode the overlying scalp, forcing removal so that the scalp can heal. Further, the long leads running under the scalp and through the neck are more susceptible to fracture due to torsional and other forces caused by normal head and neck movements.
- In general, the invention relates to a lead connection module of a modular implantable medical device. In order to provide an implantable medical device with a smaller profile so that the IMD can better fit into available body locations, various functional components of the IMD are separated into individual interconnected modules. This modular architecture for the implantable medical device permits the device footprint to be distributed over a larger area while making the profile smaller. In addition, the multiple modules and their respective flexible interconnections may permit the overall shape of the implantable medical device to be formed to better match the body location into which it is to be implanted.
- In a typical application, the component modules within the IMD are coupled to one or more leads that are deployed within a patient's body. External leads are used to electrically connect the external locations to a control module within the implantable medical device, and the control module can monitor the electrical activity, or regulate administration of therapy, or both. Accordingly, it is desirable for the external leads be both electronically and mechanically coupled to the implantable medical device. The present invention provides such a coupling of the external leads to the implantable medical device.
- In one embodiment, the invention is directed to a an implantable medical device that includes at least two interconnected modules, each of the modules comprising a housing, and an overmold that at least partially encapsulates each of the housings. The overmold comprises a lead connection module that is configured to accept an external lead. In some variations, the invention supports an overmold made of multiple materials, such as elastomeric and non-elastomeric materials.
- In another embodiment, the invention is directed to an overmold for a modular implantable medical device. The overmold comprises a first material configured to hold at least part of a module, a second material coupled to the first material, and a lead connection module configured to accept an external lead, the lead connection module being deployed within the overmold.
- The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.
- FIGS. 1A and IB are diagrams illustrating use of an implantable medical device in a patient according to an example embodiment of the present invention.
- FIG. 2 is a schematic diagram illustrating an implantable medical device according to an embodiment of the present invention.
- FIG. 3A and 3B are schematic diagrams illustrating an implantable medical device according to another embodiment of the present invention.
- FIGS. 4A-4F are schematic diagrams illustrating various orientations of multiple modules within an implantable medical device according to various embodiments of the present invention.
- FIG. 5A is a schematic diagram illustrating the construction of an overmold and modules used in construction of an implantable medical device according to the present invention.
- FIG. 5B is an exploded view of an embodiment of the overmold and modules shown in FIG. 5A.
- FIG. 5C is a side view of an embodiment of the overmold and modules shown in FIG. 5A.
- FIGS. 6A-6B are schematic diagrams illustrating an example embodiment of a multi-module implantable medical device having multiple interconnect sites according to the present invention.
- FIGS. 7A-7B are schematic diagrams illustrating an example embodiment of a multi-module implantable medical device having tethered interconnect sites according to the present invention.
- FIG. 7C is a perspective view of a multi-module implantable medical device such as that depicted in FIGS. 7A and 7B.
- FIGS. 8A-8B are schematic diagrams illustrating the interaction of components of an implantable medical device that are part of an overmold according to the present invention.
- FIGS. 9A-9B are schematic diagrams illustrating an electronic module of a multi-module implantable medical device having a connection leads according to the present invention.
- FIGS. 1A and 1B are diagrams illustrating use of an implantable medical device (IMD) in a patient according to an example embodiment of the present invention. An
IMD 101 is implanted within apatient 100 in order to permitIMD 101 to provide therapies to thepatient 100. In the example illustrated within FIGS. 1A-1B, IMD11 is implanted under the scalp of thepatient 100 in order to locate thedevice 101 as close as possible to the location ofleads 102 that provide the therapy. - FIG. 1A shows
patient 100 withIMD 101 deployed beneath his scalp. In FIG. 1A,IMD 101 is a neurostimulator that provides deep brain stimulation via leads 102 deployed in the brain ofpatient 100.IMD 101 is deployed in proximity to site of stimulation therapy.IMD 101 may be used to treat any nervous system disorder including, but not limited to, epilepsy, pain, psychological disorders including mood and anxiety disorders, movement disorders (MVD) such as, but not limited to, essential tremor and Parkinson's disease and neurodegenerative disorders. - Although
IMD 101 is depicted as a neurostimulator, the invention is not limited to applications in which the IMD is a neurostimulator. The invention may be employed with IMDs that perform any monitoring or therapeutic functions. The invention is not limited to IMDs that include leads deployed in the brain, but may also be employed with leads deployed anywhere in the head or neck including, for example, leads deployed on or near the surface of the skull, leads deployed beneath the skull such as near or on the dura mater, leads placed adjacent cranial or other nerves in the neck or head, or leads placed directly on the surface of the brain. Nor is the invention limited to IMDs that are coupled to electrodes. The invention may be employed with IMDs coupled to any sensing or therapeutic elements, such as temperature sensors or motion sensors. The invention may also be employed with different types of IMDs including, but not limited to, IMDs operating in an open loop mode (also referred to as non-responsive operation), IMDs operating in a closed loop mode (also referred to as responsive), and IMDs for providing monitoring and/or warning. - In general,
IMD 101 has a low profile, i.e.,IMD 101 is thin to permit theIMD 101 to be deployed effectively, comfortably and cosmetically and under the scalp. In one embodiment of the invention,IMD 101 has a maximum thickness of between approximately 4 millimeters and approximately 8 millimeters. The use of a reduced profile may reduce the risk of infection, skin erosion and cosmetic issued related to the implantation ofIMD 101. - Many locations within a patient do not present adequate profile for implantable medical devices. As such, many uses of such devices employ lengthy leads located remote from an implantation site of the IMD. The use of these lengthy leads requires complicated insertion procedures from the site of the IMD to the site of lead deployment that may cause medical complications to the patient as well as may lead to failures in connection leads. By constructing
IMD 101 as a set of distributed modules connected together as described herein,IMD 101 may be deployed proximate to a treatment or monitoring site. - While the embodiment of
IMD 101 shown in FIGS. 1A-1B is implanted under the scalp ofpatient 100 and may be used when the therapy provided topatient 100 includes neural stimulation of a brain, other embodiments ofIMD 100 permit the device to be implanted at many other locations within the body. In addition,IMD 101 includes a plurality of interconnected modules. Each module generally perform assigned functions. - In the typical embodiment depicted in FIG. 1B,
IMD 101 includes three modules, namely, acontrol module 103, apower supply module 104 and arecharge module 105.Control module 103 typically includes the electronic components associated with the functions ofIMD 101. In a typical implementation,control module 103 may include a hybrid circuit that includes digital circuits such as integrated circuit chips and one or more microprocessors, and analog circuit components. Accordingly,control module 103 may also be referred to as an electronic module.Power supply module 104 typically comprises one or more energy storage devices, such as a rechargeable lithium ion battery.Recharge module 105 typically includes one or more coils for transmitting or receiving electromagnetic energy through the scalp. The transmitted energy may include energy to be stored inpower supply module 104. In some embodiments, the transmitted energy may also include communication, such as information encoded in radio frequency transmissions. -
Individual modules individual modules overmold 106 which may be made of a biocompatible material. Use of the term “overmold” herein is not intend to limit the invention to embodiments in which the overmold is a molded structure. Overmold may be a molded structure, or may be a structure formed by any process. - In some embodiments of the invention,
overmold 106 encases allmodules overmold 106 is disposed over or around the modules without encasing the modules. In further embodiments, overmold 106 acts as a “frame” to hold the modules in a fixed position relative to one another, but does not fully cover the modules. Some features of the overmold, and variations on the shape of the overmold, are presented below. In general, the shape of the overmold depends upon the arrangement of the modules. The overmold may be made of a variety of materials, such as flexible silicone. The overmold may also include a rigid polymer such as Ticothane surrounded by flexible silicone. The invention is not limited to these materials, however, and the overmold may comprise any combination of elastomeric and/or non-elastomeric materials. - FIG. 2 is a schematic diagram illustrating an IMD according to another embodiment of the present invention. In this example embodiment, the
IMD 201 is arranged in a triangular configuration, and includes three modules: acontrol module 210, apower supply module 211, and arecharge module 212.Overmold 214 at least partially covers the housings ofcontrol module 210 and powersource supply module 211, and also at least partially coversrecharge module 212. These three modules are physically connected together to constructIMD 201, and any modules may also be electrically coupled to one another. -
IMD 201 also includes twolead connection modules overmold 214 includeslead connection modules connection modules module Lead connection modules IMD 210. In the case of electronic leads, for example,lead connection modules module 210. The triangular configuration ofIMD 201permits IMD 201 to possess a thin profile by spreading the modules over a larger surface area. The triangular shape also helps to keep the surface area compact. The structure ofIMD 201 may also be curved to conform to the shape of the location within a patient in which the device is being implanted. For example, implantation ofIMD 201 under the scalp of a patient may be accomplished if the overall shape ofIMD 201 is curved to follow the shape of a patient's skull. Any number of shapes may be used to match aparticular IMD 201 to an implantation location for a device. - FIG. 3A and 3B are schematic diagrams illustrating an IMD according to yet another embodiment of the present invention. In this embodiment of
IMD 301, a flat device is shown that consists of multiple modules. This embodiment of IMD 310 may be used in other locations within a patient in which the implantation location does not require such an exact match between the device and physical structures of the patient such as bone or muscle. IMD3 01 may provide a small profile when implanted as to not protrude excessively once implanted. - The flat embodiment shown in FIGS. 3A-3B may represent a device that may be a pectoral implant that may be used to treat angina, to provide vagal nerve stimulation, or to provide cardiac rhythm management. Similar devices may be implanted into an upper buttock implant location, into an abdomen location, and into periphery. A device implanted into an upper buttock location may be useful in urological and gastrological implantation therapies. A device implanted into an abdomen location may be useful in providing pain, spasticity, and chemotherapy treatment. A device implanted into a periphery location may be useful in providing muscle stimulation, on-site nerve stimulation, and diaphragm stimulation therapies.
-
IMD 301 comprises anovermold 302 that includes twolead connection modules lead connection modules overmold 302. - Additional alternate embodiments for implantable medical devices implemented according to principles of the present invention may also include non-electrical based therapies such as targeted introduction of fluids and similar therapeutic materials using pumps and reservoirs of material. One skilled in the art will recognize that any number of implantable devices may be possible without deviating from the spirit and scope of the present invention as recited within the attached claims.
- FIGS. 4A-4F are schematic diagrams illustrating exemplary configurations and orientations of modules within
IMD 401A through 401F (hereinafter 410), according to various embodiments of the present invention. IMD 401 consists of multiple modules that may be arranged into any number of orientations as shown in the various embodiments of FIGS. 4A-4F. For reference, each IMD 401 is depicted deployed proximate to the skull of a patient, withleads burr holes lead connection modules - In each of these embodiments, IMD401 has three modules as discussed above in reference to FIGS. 1B and 2: a
control module 410, apower source module 411, and arecharge module 412. Anovermold 413 at least partially covers the housings ofcontrol module 410 andpower source module 411. The modules may be arranged into a number of orientations as long as any interconnections between the modules may be routed within the device. The various embodiments include triangular configurations, as is shown in FIGS. 4A-4C, or linear configurations as shown in FIGS. 4D-4F. In FIG. 4D, one of the three modules, such as the recharge module, is deployed as atethered module 414 rather than being covered byovermold 413. - The invention is not limited to the deployments of the lead connection modules shown in FIGS. 4A-4F. The lead connection modules may be located on various positions within IMD401. Lead connection modules may be oriented, for example, to permit the leads to be routed to lead locations in an efficient manner or to support management of excess lead length. Any number of other orientations and alternate embodiments may be constructed according to principles of the present invention and consistent with the claims recited herein.
- FIGS. 5A-5C are schematic diagrams illustrating an exemplary construction of an overmold used in construction of an IMD according to the present invention. FIG. 5A illustrates that
IMD 501 comprises a set of modules 510-512, a set of motion restriction elements, such asmotion restriction fibers 521. In FIG. 5A,motion restriction fibers 521 are coupled tomodules overmold 522.Overmold 522 typically includes a solid biocompatible material.Overmold 522 may comprise an elastomeric material that is soft and flexible, such as silicone. In addition or in the alternative,overmold 522 may comprise a non-elastomeric material that imparts rigidity toIMD 501. In one embodiment, for example, a non-elastomeric material inovermold 522 acts as a “frame” to hold the modules in a fixed position relative to one another, and does not fully cover the modules.Overmold 522 covers, at least in part, the components and modules withinIMD 501 while providing a flexible structure that permits thedevice 501 to conform to fit each individual patient. Becauseovermnold 522 is typically flexible,IMD 501 may benefit from motion restriction devices such asmotion restriction fibers 521, which provide structural integrity todevice 501 once implanted into the patient. - Additional details regarding the set of
motion restriction devices 521 are described in co-pending and commonly assigned U.S. Patent Application entitled “REDUCING RELATIVE INTER-MODULE MOTION IN A DISTRIBUTED MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-333US01/P-11797.00. - FIG. 5B illustrates that the
overmold 522 may include a non-elastomeric, or “hard”component 531 in addition to an elastomeric, or “soft”component 532. In FIG. 5B, thenon-elastomeric component 531 is shaped to conform to the shape of at least one of modules 510-512 such that the modules may be restrained from motion by the non-elastomeric components. Thenon-elastomeric components 531 are typically made of a solid biocompatible material such as polysulfone, and may also be made of metal such as titanium. - The
non-elastomeric components 531 are utilized in locations in which motion is to be restricted. Any or all modules may be constrained by one or morehard components 531.Overmold 522, including elastomeric and non-elastomeric components, can be fabricated into a single structure before the modules 510-512 are inserted into thedevice 501. - Generally,
overmold 522 serves a number of functions. For example,overmold 522 incorporates motion restriction elements within thedevice 501, and attaches to modules and other elements to provide a unified device. In addition,overmold 522 provides a smooth interface surface for the device as it interacts with the patient, and protects electrical connections and feed through wires that connect modules to external leads. -
Overmold 522 may also include a durometric specific material to provide desired device qualities such as flexibility and structural integrity. In addition, the material used to constructovermold 522 may possess a thermal conductivity characteristic to either act as a heat sink, or act as an insulator to shield the patient 100 from any excess heat fromIMD 501. BecauseIMD 501 may be constructed from a large number of modules to perform a desired task, the materials selected for used in constructing theovermold 522 may vary as needed by each embodiment. - FIG. 5C illustrates that
overmold 522 provides slopedinterface 541 between anexemplary module 542 withinIMD 501 and the patient's body. In embodiments in whichIMD 501 is implanted within tight spaces, such as under the scalp of the patient, slopedinterface 541 provides a smooth transition and eases sharp edges that are known to cause possible points of stress for tissue. An angle of interface from the patient's body and the slopedinterface 541 can be approximately 135 degrees. - Additional details regarding the
overmold 522 are described in co-pending and commonly assigned U.S. Patent Application entitled “OVERMOLD FOR A MODULAR IMPLANTABLE MEDICAL DEVICE,” assigned Attorney Docket No.: 1023-332US01/P-11798.00. - FIGS. 6A-6B are schematic diagrams illustrating an example embodiment of a
multi-module IMD 601 having multiple interconnect sites according to the present invention. FIG. 6A shows a distributed IMD have multiplelead connection modules 613 that are located adjacent to each other while being near acontrol module 610. In contrast, FIG. 6B shows a distributed IMD have multiplelead connection modules 613 that are located on opposite sides of thecontrol module 610. In FIGS. 6A and 6B, lead connection modules are included inovermold 622. Thelead connection modules 613 provide a mechanism for electrically connecting electronics withincontrol module 610 to one or more external leads 643. The external leads provide an electrical signal path from a desired part of the patient's body toIMD 601. - The embodiment shown is FIG. 6A is used when it is desirable for the
external leads 643 to follow similar signal path lengths from thecontrol module 610 to the treatment or monitoring site of the body. The embodiment of FIG. 6B may be used in cases in which theexternal leads 643 are farther apart. Because thelead connection modules 613 provide electrical connections between thecontrol module 610 and the external leads 643, thelead connection modules 613 are typically located close to thecontrol module 610 to reduce a length for electrical interconnections between them. Additional details regarding the interconnection of thecontrol module 610, thelead connection modules 613, and the external leads 643 is discussed below in reference to FIGS. 8A-8B. - FIGS. 7A-7B are schematic diagrams illustrating an example embodiment of a multi-module IMD having tethered interconnect sites according to the present invention. In a first embodiment shown in FIG. 7A, an
overmold 722 of anIMD 701 may cover and connect a plurality of modules 710-712 while not coveringlead connection modules 713, which are part of a tetheredinterconnection housing 761. As shown in FIG. 7B, tetheredinterconnection housing 761 is optional. - In these embodiments, the
lead connection modules 713 that are used to connect external leads (not shown) to thedevice 701 are not contained within theovermold 722. As such, the implantation of the device would not require the insertion of external leads into the 722. In addition, the external leads may be located a distance away from theoverall device 701. Such an arrangement may assist in the management of the external leads as they are placed within the patient and routed to a lead location. - In an alternate embodiment shown in FIG. 7C,
overmold 722 may include mechanical structures such one or more grooves or a pouch to contain and route the external leads and aid lead management. An exemplary structure, agroove 750, is depicted in a perspective view ofIMD 701. In some implantations, external leads may possess an excess length that may be managed to reduce the risks of lead migration and lead damage. - FIGS. 8A-8B are schematic diagrams illustrating an exemplary interaction of components of an
IMD 801. FIG. 8A provides a side view of anovermold 822, which includes one or more soft orelastomeric components 832 and one or more hard ornon-elastomeric components 831, which interface with acontrol module 810.Non-elastomeric component 831 may be shaped to mate with themodule 810 to provide motion restriction for the module.Non-elastomeric component 831 may be mechanically connected to other modules using a motion restriction device (not shown). Theovermold 822 covers all of these components in this embodiment. A throughhole 851 may be located through thenon-elastomeric component 831 andelastomeric component 832 to provide an attachment point forIMD 801. In some embodiments,IMD 801 may be anchored in place using bone screws or other anchoring devices. Throughholes 851permit IMD 801 to be mechanically anchored to the patient once thedevice 801 is positioned at a desired location. In the embodiment shown in FIG. 8A, a bone screw inserted into throughhole 851 would seat againstnon-elastomeric component 831, but the invention encompasses embodiments in which a bone screw would seat against another component, such ascontrol module 810. - FIG. 8B illustrates a top view of the
device 801 havingelastomeric component 832 ofovermold 822 covering thenon-elastomeric components 831 thatframe control module 810. The throughhole 851 used as an attachment point is shown as part ofnon-elastomeric component 831 that is covered byelastomeric component 832. The shape ofnon-elastomeric component 831 andcontrol module 810 are shown as being rectangular in this embodiment. However, one skilled in the art will recognize that any shape for thenon-elastomeric component 831 andcontrol module 810 may be used without deviating from the spirit and scope of the present invention. - In both FIG. 8A and 8B, a
lead interconnect device 813 is included within thenon-elastomeric components 831 ofovermold 822. In these examples, thenon-elastomeric component 831 restrainscontrol module 810 and external leads 843. Typically, the external leads have iso-diametric proximal ends for connection of theexternal leads 843 toIMD 801. Anexternal lead 843 is inserted into the lead connection module in order to connect theexternal leads 843 to electronics withincontrol module 810 ofIMD 801. This electrical connection from thecontrol module 810 to the external leads 843 is made using a moduleconnection lead wire 846 that extends fromcontrol module 810 and physically connects with theexternal lead 843 within thelead connection module 813. - The
lead connection module 813 may also include a mechanicallead securing mechanism 845 that engages theexternal lead 843 to restrain its motion and ensure electrical connection with feed-throughwires 846. In the embodiment of FIG. 8A, atool 847 is used to engage the mechanicallead securing mechanism 845 within thelead connection module 813. In this embodiment, the mechanicallead securing mechanism 845 comprises a mechanical set-screw that is tightened by a screwdriver. An example of such a mechanicallead securing mechanism 845 is a low-profile DBS lead extensions manufactured by Medtronic Inc. In alternate embodiments, the mechanicallead securing mechanism 845 may be tool-less using a variety of known securing technologies that ensures theexternal lead 843 does not separate from thelead connection module 813. Tool-assisted or tool-less coupling of leads to the IMD both allow medical personnel to couple leads to the IMD quickly and securely. - FIGS. 9A-9B are schematic diagrams illustrating a control module of a multi-module IMD having a connection leads according to the present invention. FIG. 9A provides a prospective view of a
control module 910 to illustrate a set of feed-throughwires 946 that electricallycouple electronics 950 within thecontrol module 810 to external leads as discussed above in reference to FIGS. 8A and 8B. Similarly, FIG. 9B provides a side view of thecontrol module 910 of FIG. 9A to again illustrate the use of the feed-throughwires 946 as discussed above. - While the above embodiments of the present invention describe a lead interconnect module of a modular implantable medical device, one skilled in the art will recognize that the use of a module structure are merely exemplary embodiments of the present invention. It is to be understood that other embodiments may be utilized and operational changes may be made without departing from the scope of the present invention as recited in the attached claims.
- As such, the foregoing description of the exemplary embodiments of the invention has been presented for the purposes of illustration and description. They are not intended to be exhaustive or to limit the invention to the precise forms disclosed. Many modifications and variations are possible in light of the above teaching. It is intended that the scope of the invention be limited not with this detailed description, but rather by the claims appended hereto. The present invention is presently embodied as a lead interconnect module of a modular implantable medical device.
Claims (14)
1. An implantable medical device comprising:
at least two interconnected modules, each of the modules comprising a housing; and
an overmold that at least partially encapsulates each of the housings, the overmold comprising a lead connection module for accepting an external lead.
2. The implantable medical device of claim 1 , wherein at least one module comprises a control module containing electronic components.
3. The implantable medical device of claim 1 , wherein the overmold comprises a first material and a second material, and the lead connection module is deployed within the first material.
4. The implantable medical device of claim 3 , wherein the first material comprises a non-elastomeric material.
5. The implantable medical device of claim 1 , the lead connection module comprising at least one feed-through wire to electrically couple an external lead to an electronic component within the implantable medical device.
6. The implantable medical device of claim 1 , wherein the lead connection module includes a mechanical lead securing mechanism.
7. The implantable medical device of claim 6 , wherein the mechanical lead securing mechanism comprises a tool-less mechanical lead securing mechanism.
8. The implantable medical device of claim 1 , wherein the implantable medical device has a maximum thickness of between approximately 4 millimeters and approximately 8 millimeters.
9. An overmold for a modular implantable medical device comprising:
a first material configured to hold at least part of a module;
a second material coupled to the first material; and
a lead connection module configured to accept an external lead, the lead connection module being deployed within the overmold.
10. The overmold of claim 9 , wherein the first material comprises a non-elastomeric material.
11. The overmold of claim 9 , wherein the second material comprises an elastomeric material.
12. The overmold of claim 9 , wherein the second material comprises silicone.
13. The overmold of claim 9 , wherein the lead connection module is deployed within the first material.
14. The overmold of claim 9 , wherein the lead connection module is configured to receive an iso-diametric external lead.
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US10/731,881 Expired - Fee Related US7392089B2 (en) | 2002-12-09 | 2003-12-09 | Reducing relative intermodule motion in a modular implantable medical device |
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US11/735,826 Abandoned US20070185539A1 (en) | 2002-12-09 | 2007-04-16 | Overmold for a modular implantable medical device |
US12/942,806 Active 2025-07-11 US8666497B2 (en) | 2002-12-09 | 2010-11-09 | Coupling module of a modular implantable medical device |
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Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020173773A1 (en) * | 2001-04-10 | 2002-11-21 | Olsen James M. | Permanent magnet solenoid pump for an implantable therapeutic substance delivery device |
US20050075694A1 (en) * | 2003-10-02 | 2005-04-07 | Medtronic, Inc. | External power source, charger and system for an implantable medical device having thermal characteristics and method therefore |
WO2008113091A1 (en) * | 2007-03-21 | 2008-09-25 | Med-El Elektromedizinische Geräte Gesellschaft M.B.H. | System for electrically stimulating muscles or nerves |
US20100076524A1 (en) * | 2003-10-02 | 2010-03-25 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US7881796B2 (en) | 2003-05-16 | 2011-02-01 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US8086313B2 (en) | 2002-12-09 | 2011-12-27 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US8280478B2 (en) | 2004-04-29 | 2012-10-02 | Medtronic, Inc. | Evaluation of implantation site for implantation of implantable medical device |
US8666497B2 (en) | 2002-12-09 | 2014-03-04 | Medtronic, Inc. | Coupling module of a modular implantable medical device |
US20140277217A1 (en) * | 2013-03-15 | 2014-09-18 | Medtronic, Inc. | Implantable device with internal lead connector |
US9084901B2 (en) | 2006-04-28 | 2015-07-21 | Medtronic, Inc. | Cranial implant |
US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
WO2020205843A1 (en) * | 2019-04-01 | 2020-10-08 | Boston Scientific Neuromodulation Corporation | Systems and methods for making and using a low-profile control module for an electrical stimulation system |
US10912648B2 (en) | 2016-08-30 | 2021-02-09 | Longeviti Neuro Solutions Llc | Method for manufacturing a low-profile intercranial device and the low-profile intercranial device manufactured thereby |
US11058541B2 (en) | 2015-09-04 | 2021-07-13 | The Johns Hopkins University | Low-profile intercranial device |
US11357992B2 (en) | 2019-05-03 | 2022-06-14 | Boston Scientific Neuromodulation Corporation | Connector assembly for an electrical stimulation system and methods of making and using |
US11589992B2 (en) | 2018-01-09 | 2023-02-28 | Longeviti Neuro Solutions Llc | Universal low-profile intercranial assembly |
Families Citing this family (326)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8177762B2 (en) | 1998-12-07 | 2012-05-15 | C. R. Bard, Inc. | Septum including at least one identifiable feature, access ports including same, and related methods |
US7346391B1 (en) * | 1999-10-12 | 2008-03-18 | Flint Hills Scientific Llc | Cerebral or organ interface system |
US7660621B2 (en) | 2000-04-07 | 2010-02-09 | Medtronic, Inc. | Medical device introducer |
US9655705B1 (en) * | 2000-09-29 | 2017-05-23 | Precision Medical Devices, Inc. | Body canal contacting means for body fluid flow control methods and devices |
US7130675B2 (en) * | 2002-06-28 | 2006-10-31 | Tristan Technologies, Inc. | High-resolution magnetoencephalography system and method |
US7704260B2 (en) | 2002-09-17 | 2010-04-27 | Medtronic, Inc. | Low profile instrument immobilizer |
AU2003901867A0 (en) * | 2003-04-17 | 2003-05-08 | Cochlear Limited | Osseointegration fixation system for an implant |
US8270647B2 (en) | 2003-05-08 | 2012-09-18 | Advanced Bionics, Llc | Modular speech processor headpiece |
US8811643B2 (en) * | 2003-05-08 | 2014-08-19 | Advanced Bionics | Integrated cochlear implant headpiece |
US7599508B1 (en) | 2003-05-08 | 2009-10-06 | Advanced Bionics, Llc | Listening device cap |
US20050003268A1 (en) * | 2003-05-16 | 2005-01-06 | Scott Erik R. | Battery housing configuration |
US20050004637A1 (en) * | 2003-05-16 | 2005-01-06 | Ruchika Singhal | Explantation of implantable medical device |
US7317947B2 (en) * | 2003-05-16 | 2008-01-08 | Medtronic, Inc. | Headset recharger for cranially implantable medical devices |
US7082336B2 (en) * | 2003-06-04 | 2006-07-25 | Synecor, Llc | Implantable intravascular device for defibrillation and/or pacing |
JP4616252B2 (en) * | 2003-06-04 | 2011-01-19 | シネコー・エルエルシー | Intravascular electrophysiology system and method |
US7617007B2 (en) | 2003-06-04 | 2009-11-10 | Synecor Llc | Method and apparatus for retaining medical implants within body vessels |
US8239045B2 (en) | 2003-06-04 | 2012-08-07 | Synecor Llc | Device and method for retaining a medical device within a vessel |
US7840270B2 (en) | 2003-07-23 | 2010-11-23 | Synapse Biomedical, Inc. | System and method for conditioning a diaphragm of a patient |
US20050102006A1 (en) * | 2003-09-25 | 2005-05-12 | Whitehurst Todd K. | Skull-mounted electrical stimulation system |
US8024049B1 (en) * | 2003-10-20 | 2011-09-20 | University Of Central Florida Research Foundation, Inc. | Spatial-temporal deep brain stimulation methods and systems |
US9278208B1 (en) | 2003-10-20 | 2016-03-08 | University Of Central Florida Research Foundation, Inc. | Spatial-temporal deep brain stimulation methods and systems |
WO2005058415A2 (en) | 2003-12-12 | 2005-06-30 | Synecor, Llc | Implantable medical device having pre-implant exoskeleton |
US7769461B2 (en) * | 2003-12-19 | 2010-08-03 | Boston Scientific Neuromodulation Corporation | Skull-mounted electrical stimulation system and method for treating patients |
WO2005090370A1 (en) * | 2004-02-05 | 2005-09-29 | The Regents Of The University Of California | Pharmacologically active agents containing esterified phosphonates and methods for use thereof |
US20050182420A1 (en) * | 2004-02-13 | 2005-08-18 | Schulte Gregory T. | Low profile apparatus for securing a therapy delivery device within a burr hole |
US20050245984A1 (en) * | 2004-04-30 | 2005-11-03 | Medtronic, Inc. | Implantable medical device with lubricious material |
US8862235B1 (en) * | 2005-07-01 | 2014-10-14 | Alfred E. Mann Foundation For Scientific Research | Brain implant device |
US20060009814A1 (en) * | 2004-07-07 | 2006-01-12 | Alfred E. Mann Foundation For Scientific Research | Brian implant device |
US7563541B2 (en) * | 2004-10-29 | 2009-07-21 | Medtronic, Inc. | Lithium-ion battery |
US7337010B2 (en) * | 2004-10-29 | 2008-02-26 | Medtronic, Inc. | Medical device having lithium-ion battery |
CN101048898B (en) | 2004-10-29 | 2012-02-01 | 麦德托尼克公司 | Lithium-ion battery and medical device |
US7642013B2 (en) | 2004-10-29 | 2010-01-05 | Medtronic, Inc. | Medical device having lithium-ion battery |
US20080044728A1 (en) * | 2004-10-29 | 2008-02-21 | Medtronic, Inc. | Lithium-ion battery |
US7927742B2 (en) | 2004-10-29 | 2011-04-19 | Medtronic, Inc. | Negative-limited lithium-ion battery |
US7641992B2 (en) | 2004-10-29 | 2010-01-05 | Medtronic, Inc. | Medical device having lithium-ion battery |
US7662509B2 (en) * | 2004-10-29 | 2010-02-16 | Medtronic, Inc. | Lithium-ion battery |
US8105714B2 (en) | 2004-10-29 | 2012-01-31 | Medtronic, Inc. | Lithium-ion battery |
KR101326118B1 (en) * | 2004-10-29 | 2013-11-06 | 메드트로닉 인코포레이티드 | Method of charging lithium-ion battery |
US9077022B2 (en) | 2004-10-29 | 2015-07-07 | Medtronic, Inc. | Lithium-ion battery |
US8980453B2 (en) | 2008-04-30 | 2015-03-17 | Medtronic, Inc. | Formation process for lithium-ion batteries |
US7682745B2 (en) | 2004-10-29 | 2010-03-23 | Medtronic, Inc. | Medical device having lithium-ion battery |
US9065145B2 (en) | 2004-10-29 | 2015-06-23 | Medtronic, Inc. | Lithium-ion battery |
AU2005304912A1 (en) * | 2004-11-04 | 2006-05-18 | Smith & Nephew, Inc. | Cycle and load measurement device |
US20070239230A1 (en) * | 2004-12-17 | 2007-10-11 | Medtronic, Inc. | System and method for regulating cardiac triggered therapy to the brain |
US8485979B2 (en) | 2004-12-17 | 2013-07-16 | Medtronic, Inc. | System and method for monitoring or treating nervous system disorders |
US8112148B2 (en) | 2004-12-17 | 2012-02-07 | Medtronic, Inc. | System and method for monitoring cardiac signal activity in patients with nervous system disorders |
US8112153B2 (en) | 2004-12-17 | 2012-02-07 | Medtronic, Inc. | System and method for monitoring or treating nervous system disorders |
US8209019B2 (en) * | 2004-12-17 | 2012-06-26 | Medtronic, Inc. | System and method for utilizing brain state information to modulate cardiac therapy |
US8108046B2 (en) * | 2004-12-17 | 2012-01-31 | Medtronic, Inc. | System and method for using cardiac events to trigger therapy for treating nervous system disorders |
US8108038B2 (en) * | 2004-12-17 | 2012-01-31 | Medtronic, Inc. | System and method for segmenting a cardiac signal based on brain activity |
DE602005026054D1 (en) | 2004-12-17 | 2011-03-03 | Medtronic Inc | SYSTEM FOR MONITORING OR TREATING DISEASES OF THE NERVOUS SYSTEM |
US8209009B2 (en) | 2004-12-17 | 2012-06-26 | Medtronic, Inc. | System and method for segmenting a cardiac signal based on brain stimulation |
US8214035B2 (en) * | 2004-12-17 | 2012-07-03 | Medtronic, Inc. | System and method for utilizing brain state information to modulate cardiac therapy |
US7376466B2 (en) * | 2005-01-26 | 2008-05-20 | Boston Scientific Neuromodulation Corporation | Casings for implantable stimulators and methods of making the same |
US7657316B2 (en) * | 2005-02-25 | 2010-02-02 | Boston Scientific Neuromodulation Corporation | Methods and systems for stimulating a motor cortex of the brain to treat a medical condition |
US7947022B2 (en) | 2005-03-04 | 2011-05-24 | C. R. Bard, Inc. | Access port identification systems and methods |
US8029482B2 (en) | 2005-03-04 | 2011-10-04 | C. R. Bard, Inc. | Systems and methods for radiographically identifying an access port |
JP5484674B2 (en) | 2005-03-04 | 2014-05-07 | シー・アール・バード・インコーポレーテッド | Access port and identification method |
US9474888B2 (en) | 2005-03-04 | 2016-10-25 | C. R. Bard, Inc. | Implantable access port including a sandwiched radiopaque insert |
US7363082B2 (en) * | 2005-03-24 | 2008-04-22 | Synecor Llc | Flexible hermetic enclosure for implantable medical devices |
US7593538B2 (en) * | 2005-03-28 | 2009-09-22 | Starkey Laboratories, Inc. | Antennas for hearing aids |
US10307581B2 (en) | 2005-04-27 | 2019-06-04 | C. R. Bard, Inc. | Reinforced septum for an implantable medical device |
EP2308547B1 (en) | 2005-04-27 | 2014-09-17 | C.R. Bard, Inc. | High pressure access port with septum |
WO2006116613A1 (en) | 2005-04-27 | 2006-11-02 | C.R. Bard, Inc. | Infusion apparatuses |
US7684864B2 (en) * | 2005-04-28 | 2010-03-23 | Medtronic, Inc. | Subcutaneous cardioverter-defibrillator |
US7673528B2 (en) * | 2005-05-12 | 2010-03-09 | Euisik Yoon | Flexible modular sensor systems |
US8391990B2 (en) | 2005-05-18 | 2013-03-05 | Cardiac Pacemakers, Inc. | Modular antitachyarrhythmia therapy system |
WO2006135751A2 (en) | 2005-06-09 | 2006-12-21 | Medtronic, Inc. | Combination therapy including peripheral nerve field stimulation |
EP1904173B8 (en) * | 2005-06-09 | 2016-06-08 | Medtronic, Inc. | Implantable medical device with electrodes on multiple housing surfaces |
US7815667B2 (en) * | 2005-07-21 | 2010-10-19 | Pyles Stephen T | Power source for an implantable medical device |
WO2007025191A1 (en) | 2005-08-23 | 2007-03-01 | Smith & Nephew, Inc. | Telemetric orthopaedic implant |
US9050005B2 (en) | 2005-08-25 | 2015-06-09 | Synapse Biomedical, Inc. | Method and apparatus for transgastric neurostimulation |
CA2562205A1 (en) * | 2005-09-28 | 2007-03-28 | Medtrode Inc. | Implantable transcranial pulse generator having a collapsible portion |
US20070123923A1 (en) * | 2005-11-30 | 2007-05-31 | Lindstrom Curtis C | Implantable medical device minimizing rotation and dislocation |
US20070142696A1 (en) | 2005-12-08 | 2007-06-21 | Ventrassist Pty Ltd | Implantable medical devices |
DE602006014591D1 (en) * | 2005-12-15 | 2010-07-08 | Cardiac Pacemakers Inc | METHOD AND DEVICE FOR A SMALL POWER SOURCE FOR AN IMPLANTABLE DEVICE |
US9616223B2 (en) * | 2005-12-30 | 2017-04-11 | Medtronic, Inc. | Media-exposed interconnects for transducers |
US9849216B2 (en) * | 2006-03-03 | 2017-12-26 | Smith & Nephew, Inc. | Systems and methods for delivering a medicament |
WO2007103585A2 (en) | 2006-03-09 | 2007-09-13 | Synapse Biomedical, Inc. | Ventilator assist system and method to improve respiratory function |
WO2007117538A2 (en) * | 2006-04-03 | 2007-10-18 | Innerpulse, Inc. | Flexible interconnect assembly for implantable medical devices |
DE102006018851A1 (en) * | 2006-04-22 | 2007-10-25 | Biotronik Crm Patent Ag | Active medical device implant with at least two diagnostic and / or therapeutic functions |
US7856272B2 (en) * | 2006-04-28 | 2010-12-21 | Flint Hills Scientific, L.L.C. | Implantable interface for a medical device system |
CN101553167B (en) * | 2006-05-12 | 2013-04-24 | 因维沃公司 | Method of interfacing a detachable display system to a base unit for use in MRI |
US20080097153A1 (en) * | 2006-08-24 | 2008-04-24 | Ignagni Anthony R | Method and apparatus for grasping an abdominal wall |
US7894915B1 (en) | 2006-10-27 | 2011-02-22 | Pacesetter, Inc. | Implantable medical device |
US7899537B1 (en) * | 2006-10-27 | 2011-03-01 | Pacesetter, Inc. | Pericardial cardioverter defibrillator |
US8401648B2 (en) * | 2006-10-31 | 2013-03-19 | Medtronic, Inc. | Housing for implantable medical device |
US9265912B2 (en) | 2006-11-08 | 2016-02-23 | C. R. Bard, Inc. | Indicia informative of characteristics of insertable medical devices |
US9642986B2 (en) | 2006-11-08 | 2017-05-09 | C. R. Bard, Inc. | Resource information key for an insertable medical device |
US20080147168A1 (en) * | 2006-12-04 | 2008-06-19 | Terrance Ransbury | Intravascular implantable device having detachable tether arrangement |
US8311633B2 (en) * | 2006-12-04 | 2012-11-13 | Synecor Llc | Intravascular implantable device having superior anchoring arrangement |
EP2121124A1 (en) * | 2006-12-15 | 2009-11-25 | Nasophlex B.V. | Resuscitation device and method for resuscitation |
WO2008098001A2 (en) | 2007-02-05 | 2008-08-14 | Synapse Biomedical, Inc. | Removable intramuscular electrode |
EP2114247B1 (en) | 2007-02-23 | 2013-10-30 | Smith & Nephew, Inc. | Processing sensed accelerometer data for determination of bone healing |
US8512264B1 (en) | 2007-04-06 | 2013-08-20 | Wilson T. Asfora | Analgesic implant device and system |
US8469908B2 (en) * | 2007-04-06 | 2013-06-25 | Wilson T. Asfora | Analgesic implant device and system |
US9554721B1 (en) * | 2007-04-23 | 2017-01-31 | Neurowave Systems Inc. | Seizure detector, brain dysfunction monitor and method |
US9561053B2 (en) | 2007-04-25 | 2017-02-07 | Medtronic, Inc. | Implant tool to facilitate medical device implantation |
US9399130B2 (en) | 2007-04-25 | 2016-07-26 | Medtronic, Inc. | Cannula configured to deliver test stimulation |
US8000788B2 (en) | 2007-04-27 | 2011-08-16 | Medtronic, Inc. | Implantable medical device for treating neurological conditions including ECG sensing |
US9820671B2 (en) | 2007-05-17 | 2017-11-21 | Synapse Biomedical, Inc. | Devices and methods for assessing motor point electromyogram as a biomarker |
ES2651269T3 (en) | 2007-06-20 | 2018-01-25 | Medical Components, Inc. | Venous reservoir with molded indications and / or radiopacas |
WO2009012395A1 (en) | 2007-07-19 | 2009-01-22 | Innovative Medical Devices, Llc | Venous access port assembly with x-ray discernable indicia |
EP3311877A1 (en) | 2007-07-19 | 2018-04-25 | Medical Components, Inc. | Venous access port assembly with x-ray discernable indicia |
EP2185236B1 (en) | 2007-07-27 | 2015-10-07 | Second Sight Medical Products | Implantable device for the brain |
US8060218B2 (en) * | 2007-08-02 | 2011-11-15 | Synecor, Llc | Inductive element for intravascular implantable devices |
JP5425077B2 (en) * | 2007-08-23 | 2014-02-26 | バイオネス インコーポレイテッド | System for transmitting current to body tissue |
US9757554B2 (en) | 2007-08-23 | 2017-09-12 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
US8738137B2 (en) | 2007-08-23 | 2014-05-27 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
CN107115591A (en) | 2007-09-06 | 2017-09-01 | 史密夫和内修有限公司 | System and method for being communicated with remote measurement implant |
US20090082827A1 (en) * | 2007-09-26 | 2009-03-26 | Cardiac Pacemakers, Inc. | Hinged anchors for wireless pacing electrodes |
CA2697826A1 (en) * | 2007-10-09 | 2009-04-16 | Imthera Medical, Inc. | System and method for neural stimulation |
WO2009059033A1 (en) | 2007-10-30 | 2009-05-07 | Synapse Biomedical, Inc. | Method of improving sleep disordered breathing |
US8428726B2 (en) | 2007-10-30 | 2013-04-23 | Synapse Biomedical, Inc. | Device and method of neuromodulation to effect a functionally restorative adaption of the neuromuscular system |
US9248280B2 (en) * | 2007-11-02 | 2016-02-02 | Boston Scientific Neuromodulation Corporation | Closed-loop feedback for steering stimulation energy within tissue |
US20090118804A1 (en) * | 2007-11-05 | 2009-05-07 | Advanced Bionics Corporation | Method of mounting minimally invasive plug electrodes within cranium of patient |
US9579496B2 (en) | 2007-11-07 | 2017-02-28 | C. R. Bard, Inc. | Radiopaque and septum-based indicators for a multi-lumen implantable port |
US8165694B2 (en) * | 2008-01-29 | 2012-04-24 | Boston Scientific Neuromodulation Corporation | Thermal management of implantable medical devices |
US8024045B2 (en) * | 2008-02-08 | 2011-09-20 | Intelect Medical, Inc. | Multi-functional burr hole assembly |
US20090216324A1 (en) * | 2008-02-22 | 2009-08-27 | Leigh Charles R A | Malleable implantable medical device |
JP2009225935A (en) * | 2008-03-21 | 2009-10-08 | Nitto Denko Corp | Bodily fluid collecting circuit board and biosensor |
US20090281623A1 (en) * | 2008-05-12 | 2009-11-12 | Medtronic, Inc. | Customization of implantable medical devices |
US20090312835A1 (en) * | 2008-06-17 | 2009-12-17 | Greatbatch Ltd. | Dielectric fluid filled active implantable medical devices |
NL2001698C2 (en) | 2008-06-18 | 2009-12-22 | Nasophlex B V | Cardioverter / defibrillator. |
WO2009154456A1 (en) * | 2008-06-18 | 2009-12-23 | Kerphos B.V. | A flexible electronic system for producing a stimulation signal to the human body. |
NL2001697C2 (en) | 2008-06-18 | 2009-12-22 | Nasophlex B V | Nose stimulator for producing a stimulation signal to a nose. |
NL2001694C2 (en) * | 2008-06-18 | 2009-12-22 | Nasophlex B V | Ear stimulator for producing a stimulation signal to an ear. |
EP3536376A1 (en) | 2008-07-30 | 2019-09-11 | Ecole Polytechnique Fédérale de Lausanne | Apparatus for optimized stimulation of a neurological target |
US8335551B2 (en) * | 2008-09-29 | 2012-12-18 | Chong Il Lee | Method and means for connecting a large number of electrodes to a measuring device |
WO2010045473A2 (en) | 2008-10-15 | 2010-04-22 | Smith & Nephew, Inc. | Composite internal fixators |
EP2367596A1 (en) * | 2008-10-31 | 2011-09-28 | Medtronic, Inc. | Shunt-current reduction housing for an implantable therapy system |
US8560060B2 (en) | 2008-10-31 | 2013-10-15 | Medtronic, Inc. | Isolation of sensing and stimulation circuitry |
US9192769B2 (en) | 2008-10-31 | 2015-11-24 | Medtronic, Inc. | Shunt-current reduction techniques for an implantable therapy system |
EP2346553B1 (en) | 2008-10-31 | 2022-01-19 | C.R. Bard, Inc. | Systems and methods for identifying an access port |
US8498698B2 (en) * | 2008-10-31 | 2013-07-30 | Medtronic, Inc. | Isolation of sensing and stimulation circuitry |
JP5667987B2 (en) | 2008-11-12 | 2015-02-12 | エコーレ ポリテクニーク フェデラーレ デ ローザンヌ (イーピーエフエル) | Micromachined nerve stimulation device |
US8932271B2 (en) | 2008-11-13 | 2015-01-13 | C. R. Bard, Inc. | Implantable medical devices including septum-based indicators |
US11890443B2 (en) | 2008-11-13 | 2024-02-06 | C. R. Bard, Inc. | Implantable medical devices including septum-based indicators |
US8321028B1 (en) | 2008-12-02 | 2012-11-27 | Advanced Bionics | Impact resistant implantable antenna coil assembly |
US8591562B2 (en) * | 2008-12-02 | 2013-11-26 | University Of Washington | Methods and devices for brain cooling for treatment and prevention of acquired epilepsy |
US9522081B2 (en) | 2008-12-02 | 2016-12-20 | University Of Washington | Methods and devices for brain cooling for treatment and/or prevention of epileptic seizures |
US8565457B2 (en) | 2008-12-19 | 2013-10-22 | Starkey Laboratories, Inc. | Antennas for standard fit hearing assistance devices |
US8699733B2 (en) | 2008-12-19 | 2014-04-15 | Starkey Laboratories, Inc. | Parallel antennas for standard fit hearing assistance devices |
US10142747B2 (en) | 2008-12-19 | 2018-11-27 | Starkey Laboratories, Inc. | Three dimensional substrate for hearing assistance devices |
US8737658B2 (en) * | 2008-12-19 | 2014-05-27 | Starkey Laboratories, Inc. | Three dimensional substrate for hearing assistance devices |
US8494197B2 (en) | 2008-12-19 | 2013-07-23 | Starkey Laboratories, Inc. | Antennas for custom fit hearing assistance devices |
US8704124B2 (en) | 2009-01-29 | 2014-04-22 | Smith & Nephew, Inc. | Low temperature encapsulate welding |
EP2258442A1 (en) * | 2009-06-03 | 2010-12-08 | Greatbatch Ltd. | Dielectric fluid filled active implantable medical devices |
US20110004288A1 (en) * | 2009-06-12 | 2011-01-06 | Terrance Ransbury | Intravascular implantable device having integrated anchor mechanism |
US20100318166A1 (en) * | 2009-06-12 | 2010-12-16 | Terrance Ransbury | Methods and systems for anti-thrombotic intravascular implantable devices |
US8715244B2 (en) | 2009-07-07 | 2014-05-06 | C. R. Bard, Inc. | Extensible internal bolster for a medical device |
US10286218B2 (en) | 2009-07-31 | 2019-05-14 | Medtronic, Inc. | Connector enclosure assemblies of medical devices including an angled lead passageway |
WO2012102971A1 (en) | 2011-01-26 | 2012-08-02 | Medtronic, Inc. | Implantable medical devices and related connector enclosure assemblies utilizing conductors electrically coupled to feedthrough pins |
JP2013510652A (en) | 2009-11-17 | 2013-03-28 | シー・アール・バード・インコーポレーテッド | Overmolded access port including locking feature and identification feature |
JP2013512062A (en) | 2009-12-01 | 2013-04-11 | エコーレ ポリテクニーク フェデラーレ デ ローザンヌ | Microfabricated surface nerve stimulation device and methods of making and using the same |
US8744568B2 (en) * | 2009-12-22 | 2014-06-03 | Boston Scientific Scimed, Inc. | Medical device with electroactive polymer powered by photovoltaic cell |
WO2011091071A2 (en) * | 2010-01-20 | 2011-07-28 | The Regents Of The University Of California | Systems, devices and methods for cranial implantation of a neuromodulation device |
US8527065B2 (en) * | 2010-02-11 | 2013-09-03 | Biotronik Se & Co. Kg | Electrode device for active medical implant |
US9549708B2 (en) | 2010-04-01 | 2017-01-24 | Ecole Polytechnique Federale De Lausanne | Device for interacting with neurological tissue and methods of making and using the same |
US9216297B2 (en) | 2010-04-05 | 2015-12-22 | Medtronic, Inc. | Flexible recharge coil techniques |
US8594806B2 (en) | 2010-04-30 | 2013-11-26 | Cyberonics, Inc. | Recharging and communication lead for an implantable device |
AU2011338308B2 (en) * | 2010-12-09 | 2015-07-30 | Heartware, Inc. | Controller and power source for implantable blood pump |
WO2012091989A2 (en) | 2010-12-28 | 2012-07-05 | Medtronic, Inc. | Medical devices including metallic connector enclosures |
USD676955S1 (en) | 2010-12-30 | 2013-02-26 | C. R. Bard, Inc. | Implantable access port |
USD682416S1 (en) | 2010-12-30 | 2013-05-14 | C. R. Bard, Inc. | Implantable access port |
FR2970874B1 (en) * | 2011-01-27 | 2013-03-01 | Pierre Sabin | PERMANENT PERCENTANE ELECTRICAL CONNECTION DEVICE AND METHOD FOR MANUFACTURING THE SAME |
US8515540B2 (en) | 2011-02-24 | 2013-08-20 | Cochlear Limited | Feedthrough having a non-linear conductor |
AU2012240239B2 (en) | 2011-04-04 | 2017-01-05 | Curonix Llc | Implantable lead |
US9901268B2 (en) | 2011-04-13 | 2018-02-27 | Branchpoint Technologies, Inc. | Sensor, circuitry, and method for wireless intracranial pressure monitoring |
US9287580B2 (en) | 2011-07-27 | 2016-03-15 | Medtronic, Inc. | Battery with auxiliary electrode |
TR201802844T4 (en) | 2011-09-15 | 2018-03-21 | Andresen Chad | Relay module for implant. |
US9950179B2 (en) * | 2011-10-28 | 2018-04-24 | Medtronic, Inc. | Medical devices for trial stimulation |
USD751200S1 (en) | 2011-12-08 | 2016-03-08 | Heartware, Inc. | Controller for implantable blood pump |
US20130149560A1 (en) | 2011-12-09 | 2013-06-13 | Medtronic, Inc. | Auxiliary electrode for lithium-ion battery |
US20150018728A1 (en) | 2012-01-26 | 2015-01-15 | Bluewind Medical Ltd. | Wireless neurostimulators |
US9630231B2 (en) | 2012-01-27 | 2017-04-25 | Nuvectra Corporation | Superplastic forming for titanium implant enclosures |
US9981137B2 (en) | 2012-01-27 | 2018-05-29 | Nuvectra Corporation | Heat dispersion for implantable medical devices |
US9283397B2 (en) * | 2012-01-31 | 2016-03-15 | Christopher C. Stancer | Charge control for high voltage therapy energy storage component |
US9630018B2 (en) | 2012-01-31 | 2017-04-25 | Medtronic, Inc. | Charge control for high voltage therapy energy storage component |
EP2626109A1 (en) * | 2012-02-08 | 2013-08-14 | Sapiens Steering Brain Stimulation B.V. | A probe system for brain applications |
US9510953B2 (en) | 2012-03-16 | 2016-12-06 | Vertebral Technologies, Inc. | Modular segmented disc nucleus implant |
US9681836B2 (en) | 2012-04-23 | 2017-06-20 | Cyberonics, Inc. | Methods, systems and apparatuses for detecting seizure and non-seizure states |
AU2013294705B2 (en) | 2012-07-26 | 2018-02-01 | Nyxoah SA | Implant sleep apnea treatment device including an antenna |
US9343923B2 (en) | 2012-08-23 | 2016-05-17 | Cyberonics, Inc. | Implantable medical device with backscatter signal based communication |
US9849025B2 (en) | 2012-09-07 | 2017-12-26 | Yale University | Brain cooling system |
US9935498B2 (en) | 2012-09-25 | 2018-04-03 | Cyberonics, Inc. | Communication efficiency with an implantable medical device using a circulator and a backscatter signal |
CN104884122B (en) | 2012-11-21 | 2016-12-07 | 纽佩斯公司 | Injectable subcutaneous chordal shaped cardiac devices |
WO2014087337A1 (en) | 2012-12-06 | 2014-06-12 | Bluewind Medical Ltd. | Delivery of implantable neurostimulators |
US20140163626A1 (en) * | 2012-12-12 | 2014-06-12 | Grahame Walling | Implantable device migration control |
FR2999441B1 (en) * | 2012-12-14 | 2016-01-01 | Commissariat Energie Atomique | HERMETIC HOUSING, ESPECIALLY FOR ENCAPSULATION OF AN IMPLANTABLE MEDICAL DEVICE. |
EP2938393A1 (en) | 2012-12-26 | 2015-11-04 | Micron Devices, LLC | Wearable antenna assembly |
US8849408B1 (en) | 2013-01-04 | 2014-09-30 | University Of Central Florida Research Foundation, Inc. | Methods for electronic directionality of deep-brain stimulation |
WO2014143460A1 (en) * | 2013-03-12 | 2014-09-18 | Cardiac Pacemakers, Inc. | Implantable medical device and assembly thereof |
US9439686B2 (en) | 2013-03-15 | 2016-09-13 | Warsaw Orthopedic, Inc. | Spinal correction system and method |
US9440076B2 (en) | 2013-03-15 | 2016-09-13 | Globus Medical, Inc. | Spinal cord stimulator system |
US9887574B2 (en) | 2013-03-15 | 2018-02-06 | Globus Medical, Inc. | Spinal cord stimulator system |
US9872997B2 (en) | 2013-03-15 | 2018-01-23 | Globus Medical, Inc. | Spinal cord stimulator system |
US9878170B2 (en) | 2013-03-15 | 2018-01-30 | Globus Medical, Inc. | Spinal cord stimulator system |
EP2994191A1 (en) * | 2013-05-10 | 2016-03-16 | Advanced Bionics AG | Thin profile cochlear implants |
US20160166837A1 (en) * | 2013-07-11 | 2016-06-16 | Newpace Ltd. | Battery and electronics integration in an implantable medical device |
US10610693B2 (en) * | 2013-07-11 | 2020-04-07 | Newpace Ltd. | Battery and electronics integration in a flexible implantable medical device |
US20150038948A1 (en) * | 2013-07-31 | 2015-02-05 | G-Tech Electronic Research & Development, LLC | Apparatus and use of a neurochemisrty regulator device insertable in the cranium for the treatment of cerebral cortical disorders |
US9042991B2 (en) | 2013-08-14 | 2015-05-26 | Syntilla Medical LLC | Implantable head mounted neurostimulation system for head pain |
USD751201S1 (en) | 2013-08-26 | 2016-03-08 | Heartware, Inc. | Handheld controller |
US9403024B2 (en) | 2013-09-05 | 2016-08-02 | Boston Scientific Neuromodulation Corporation | Construction for an implantable medical device employing an internal support structure |
US10960215B2 (en) | 2013-10-23 | 2021-03-30 | Nuxcel, Inc. | Low profile head-located neurostimulator and method of fabrication |
WO2015081025A1 (en) | 2013-11-29 | 2015-06-04 | The Johns Hopkins University | Cranial reference mount |
CN106102830B (en) | 2014-01-10 | 2019-07-16 | 心脏起搏器股份公司 | For improving the method and system of the communication between medical device |
WO2015106015A1 (en) | 2014-01-10 | 2015-07-16 | Cardiac Pacemakers, Inc. | Systems and methods for detecting cardiac arrhythmias |
US9901269B2 (en) | 2014-04-17 | 2018-02-27 | Branchpoint Technologies, Inc. | Wireless intracranial monitoring system |
US9848789B2 (en) | 2014-04-17 | 2017-12-26 | Branchpoint Technologies, Inc. | Wireless intracranial monitoring system |
EP3476430B1 (en) | 2014-05-16 | 2020-07-01 | Aleva Neurotherapeutics SA | Device for interacting with neurological tissue |
US11311718B2 (en) | 2014-05-16 | 2022-04-26 | Aleva Neurotherapeutics Sa | Device for interacting with neurological tissue and methods of making and using the same |
US9474894B2 (en) | 2014-08-27 | 2016-10-25 | Aleva Neurotherapeutics | Deep brain stimulation lead |
US9403011B2 (en) | 2014-08-27 | 2016-08-02 | Aleva Neurotherapeutics | Leadless neurostimulator |
WO2016033197A2 (en) | 2014-08-28 | 2016-03-03 | Cardiac Pacemakers, Inc. | Medical device with triggered blanking period |
EP3191169B1 (en) | 2014-09-08 | 2021-11-03 | Newpace Ltd. | Flexible rechargeable implantable subcutaneous medical device structure |
EP3223752A4 (en) | 2014-11-24 | 2018-09-12 | The Johns Hopkins University | A cutting machine for resizing raw implants during surgery |
US10434300B2 (en) * | 2014-12-01 | 2019-10-08 | Cardiac Pacemaker, Inc. | Implantable medical device with stacked circuit components |
US9579511B2 (en) * | 2014-12-15 | 2017-02-28 | Medtronic, Inc. | Medical device with surface mounted lead connector |
ES2713231T3 (en) | 2015-02-06 | 2019-05-20 | Cardiac Pacemakers Inc | Systems for the safe supply of electrical stimulation therapy |
JP6510660B2 (en) | 2015-02-06 | 2019-05-08 | カーディアック ペースメイカーズ, インコーポレイテッド | System and method for treating cardiac arrhythmias |
US10046167B2 (en) | 2015-02-09 | 2018-08-14 | Cardiac Pacemakers, Inc. | Implantable medical device with radiopaque ID tag |
US11285326B2 (en) | 2015-03-04 | 2022-03-29 | Cardiac Pacemakers, Inc. | Systems and methods for treating cardiac arrhythmias |
WO2016149262A1 (en) | 2015-03-18 | 2016-09-22 | Cardiac Pacemakers, Inc. | Communications in a medical device system with link quality assessment |
US10050700B2 (en) | 2015-03-18 | 2018-08-14 | Cardiac Pacemakers, Inc. | Communications in a medical device system with temporal optimization |
US10232169B2 (en) | 2015-07-23 | 2019-03-19 | Boston Scientific Neuromodulation Corporation | Burr hole plugs for electrical stimulation systems and methods of making and using |
EP3337558A1 (en) | 2015-08-20 | 2018-06-27 | Cardiac Pacemakers, Inc. | Systems and methods for communication between medical devices |
US10357159B2 (en) | 2015-08-20 | 2019-07-23 | Cardiac Pacemakers, Inc | Systems and methods for communication between medical devices |
US9956414B2 (en) | 2015-08-27 | 2018-05-01 | Cardiac Pacemakers, Inc. | Temporal configuration of a motion sensor in an implantable medical device |
US9968787B2 (en) | 2015-08-27 | 2018-05-15 | Cardiac Pacemakers, Inc. | Spatial configuration of a motion sensor in an implantable medical device |
US9770597B2 (en) * | 2015-08-27 | 2017-09-26 | Precision Medical Devices, Inc. | Telemetry port for implanted medical device |
CN108136189B (en) | 2015-08-28 | 2021-10-15 | 心脏起搏器股份公司 | System for behavioral response signal detection and therapy delivery |
WO2017040115A1 (en) | 2015-08-28 | 2017-03-09 | Cardiac Pacemakers, Inc. | System for detecting tamponade |
US10226631B2 (en) | 2015-08-28 | 2019-03-12 | Cardiac Pacemakers, Inc. | Systems and methods for infarct detection |
WO2017044389A1 (en) | 2015-09-11 | 2017-03-16 | Cardiac Pacemakers, Inc. | Arrhythmia detection and confirmation |
EP3359251B1 (en) | 2015-10-08 | 2019-08-07 | Cardiac Pacemakers, Inc. | Adjusting pacing rates in an implantable medical device |
US10105540B2 (en) | 2015-11-09 | 2018-10-23 | Bluewind Medical Ltd. | Optimization of application of current |
US20200254249A1 (en) | 2015-11-17 | 2020-08-13 | Inspire Medical Systems, Inc. | Microstimulation sleep disordered breathing (sdb) therapy device |
US10576292B2 (en) | 2015-11-29 | 2020-03-03 | Boston Scientific Neuromodulation Corporation | Skull-mounted deep brain stimulator |
EP3389775B1 (en) | 2015-12-17 | 2019-09-25 | Cardiac Pacemakers, Inc. | Conducted communication in a medical device system |
US10905886B2 (en) | 2015-12-28 | 2021-02-02 | Cardiac Pacemakers, Inc. | Implantable medical device for deployment across the atrioventricular septum |
WO2017127548A1 (en) | 2016-01-19 | 2017-07-27 | Cardiac Pacemakers, Inc. | Devices for wirelessly recharging a rechargeable battery of an implantable medical device |
CN109069824B (en) | 2016-02-02 | 2022-09-16 | 阿莱瓦神经治疗股份有限公司 | Treatment of autoimmune diseases using deep brain stimulation |
WO2017136548A1 (en) | 2016-02-04 | 2017-08-10 | Cardiac Pacemakers, Inc. | Delivery system with force sensor for leadless cardiac device |
WO2017173275A1 (en) | 2016-03-31 | 2017-10-05 | Cardiac Pacemakers, Inc. | Implantable medical device with rechargeable battery |
US10328272B2 (en) | 2016-05-10 | 2019-06-25 | Cardiac Pacemakers, Inc. | Retrievability for implantable medical devices |
US10668294B2 (en) | 2016-05-10 | 2020-06-02 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker configured for over the wire delivery |
US10232168B2 (en) | 2016-06-27 | 2019-03-19 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for active skull replacement for brain interface and method of using the same |
US10512784B2 (en) | 2016-06-27 | 2019-12-24 | Cardiac Pacemakers, Inc. | Cardiac therapy system using subcutaneously sensed P-waves for resynchronization pacing management |
WO2018009569A1 (en) | 2016-07-06 | 2018-01-11 | Cardiac Pacemakers, Inc. | Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
US10426962B2 (en) | 2016-07-07 | 2019-10-01 | Cardiac Pacemakers, Inc. | Leadless pacemaker using pressure measurements for pacing capture verification |
WO2018017226A1 (en) | 2016-07-20 | 2018-01-25 | Cardiac Pacemakers, Inc. | System for utilizing an atrial contraction timing fiducial in a leadless cardiac pacemaker system |
US10238871B2 (en) | 2016-08-02 | 2019-03-26 | Cochlear Limited | Implantable medical device arrangements |
WO2018035343A1 (en) | 2016-08-19 | 2018-02-22 | Cardiac Pacemakers, Inc. | Trans septal implantable medical device |
EP3503970B1 (en) | 2016-08-24 | 2023-01-04 | Cardiac Pacemakers, Inc. | Cardiac resynchronization using fusion promotion for timing management |
CN109640809B (en) | 2016-08-24 | 2021-08-17 | 心脏起搏器股份公司 | Integrated multi-device cardiac resynchronization therapy using P-wave to pacing timing |
US10905889B2 (en) | 2016-09-21 | 2021-02-02 | Cardiac Pacemakers, Inc. | Leadless stimulation device with a housing that houses internal components of the leadless stimulation device and functions as the battery case and a terminal of an internal battery |
US10758737B2 (en) | 2016-09-21 | 2020-09-01 | Cardiac Pacemakers, Inc. | Using sensor data from an intracardially implanted medical device to influence operation of an extracardially implantable cardioverter |
WO2018057626A1 (en) | 2016-09-21 | 2018-03-29 | Cardiac Pacemakers, Inc. | Implantable cardiac monitor |
WO2018081237A1 (en) | 2016-10-27 | 2018-05-03 | Cardiac Pacemakers, Inc. | Use of a separate device in managing the pace pulse energy of a cardiac pacemaker |
US10765871B2 (en) | 2016-10-27 | 2020-09-08 | Cardiac Pacemakers, Inc. | Implantable medical device with pressure sensor |
US10463305B2 (en) | 2016-10-27 | 2019-11-05 | Cardiac Pacemakers, Inc. | Multi-device cardiac resynchronization therapy with timing enhancements |
US10413733B2 (en) | 2016-10-27 | 2019-09-17 | Cardiac Pacemakers, Inc. | Implantable medical device with gyroscope |
EP3532159B1 (en) | 2016-10-27 | 2021-12-22 | Cardiac Pacemakers, Inc. | Implantable medical device delivery system with integrated sensor |
US10561330B2 (en) | 2016-10-27 | 2020-02-18 | Cardiac Pacemakers, Inc. | Implantable medical device having a sense channel with performance adjustment |
JP6843235B2 (en) | 2016-10-31 | 2021-03-17 | カーディアック ペースメイカーズ, インコーポレイテッド | Systems and methods for activity level pacing |
CN109890456B (en) | 2016-10-31 | 2023-06-13 | 心脏起搏器股份公司 | System for activity level pacing |
WO2018089311A1 (en) | 2016-11-08 | 2018-05-17 | Cardiac Pacemakers, Inc | Implantable medical device for atrial deployment |
US10632313B2 (en) | 2016-11-09 | 2020-04-28 | Cardiac Pacemakers, Inc. | Systems, devices, and methods for setting cardiac pacing pulse parameters for a cardiac pacing device |
US10881863B2 (en) | 2016-11-21 | 2021-01-05 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker with multimode communication |
US10639486B2 (en) | 2016-11-21 | 2020-05-05 | Cardiac Pacemakers, Inc. | Implantable medical device with recharge coil |
US10894163B2 (en) | 2016-11-21 | 2021-01-19 | Cardiac Pacemakers, Inc. | LCP based predictive timing for cardiac resynchronization |
US10881869B2 (en) | 2016-11-21 | 2021-01-05 | Cardiac Pacemakers, Inc. | Wireless re-charge of an implantable medical device |
CN109996585B (en) | 2016-11-21 | 2023-06-13 | 心脏起搏器股份公司 | Implantable medical device with magnetically permeable housing and induction coil disposed around the housing |
US10124178B2 (en) | 2016-11-23 | 2018-11-13 | Bluewind Medical Ltd. | Implant and delivery tool therefor |
US11207532B2 (en) | 2017-01-04 | 2021-12-28 | Cardiac Pacemakers, Inc. | Dynamic sensing updates using postural input in a multiple device cardiac rhythm management system |
AU2018208485B2 (en) | 2017-01-10 | 2022-12-01 | Inspire Medical Systems, Inc. | Power element for an implantable medical device |
CN110234392B (en) | 2017-01-26 | 2023-08-11 | 心脏起搏器股份公司 | Leadless device with overmolded component |
EP3573708B1 (en) | 2017-01-26 | 2021-03-10 | Cardiac Pacemakers, Inc. | Leadless implantable device with detachable fixation |
JP7000438B2 (en) | 2017-01-26 | 2022-01-19 | カーディアック ペースメイカーズ, インコーポレイテッド | Human device communication with redundant message transmission |
US10758734B2 (en) * | 2017-02-28 | 2020-09-01 | Boston Scientific Neuromodulation Corporation | Implantable medical device with a silicone housing |
AU2018248361B2 (en) | 2017-04-03 | 2020-08-27 | Cardiac Pacemakers, Inc. | Cardiac pacemaker with pacing pulse energy adjustment based on sensed heart rate |
US10905872B2 (en) | 2017-04-03 | 2021-02-02 | Cardiac Pacemakers, Inc. | Implantable medical device with a movable electrode biased toward an extended position |
US20180353764A1 (en) | 2017-06-13 | 2018-12-13 | Bluewind Medical Ltd. | Antenna configuration |
US11065459B2 (en) | 2017-08-18 | 2021-07-20 | Cardiac Pacemakers, Inc. | Implantable medical device with pressure sensor |
US10918875B2 (en) | 2017-08-18 | 2021-02-16 | Cardiac Pacemakers, Inc. | Implantable medical device with a flux concentrator and a receiving coil disposed about the flux concentrator |
US10994147B2 (en) * | 2017-08-31 | 2021-05-04 | Medtronic, Inc. | Implantable medical device structures |
US10646254B2 (en) * | 2017-09-06 | 2020-05-12 | Medtronic, Inc. | Shifting burr cap assembly |
CN111107899B (en) | 2017-09-20 | 2024-04-02 | 心脏起搏器股份公司 | Implantable medical device with multiple modes of operation |
US11185703B2 (en) | 2017-11-07 | 2021-11-30 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker for bundle of his pacing |
US11103716B2 (en) | 2017-11-13 | 2021-08-31 | Boston Scientific Neuromodulation Corporation | Systems and methods for making and using a low-profile control module for an electrical stimulation system |
WO2019108830A1 (en) | 2017-12-01 | 2019-06-06 | Cardiac Pacemakers, Inc. | Leadless cardiac pacemaker with reversionary behavior |
WO2019108482A1 (en) | 2017-12-01 | 2019-06-06 | Cardiac Pacemakers, Inc. | Methods and systems for detecting atrial contraction timing fiducials and determining a cardiac interval from a ventricularly implanted leadless cardiac pacemaker |
EP3717059A1 (en) | 2017-12-01 | 2020-10-07 | Cardiac Pacemakers, Inc. | Methods and systems for detecting atrial contraction timing fiducials within a search window from a ventricularly implanted leadless cardiac pacemaker |
CN111417433A (en) | 2017-12-01 | 2020-07-14 | 心脏起搏器股份公司 | Method and system for detecting atrial contraction timing reference during ventricular filling from a ventricular implanted leadless cardiac pacemaker |
US10554069B2 (en) * | 2017-12-15 | 2020-02-04 | Medtronic, Inc. | Medical device temperature estimation |
US11529523B2 (en) | 2018-01-04 | 2022-12-20 | Cardiac Pacemakers, Inc. | Handheld bridge device for providing a communication bridge between an implanted medical device and a smartphone |
US10874861B2 (en) | 2018-01-04 | 2020-12-29 | Cardiac Pacemakers, Inc. | Dual chamber pacing without beat-to-beat communication |
US11497914B2 (en) | 2018-01-16 | 2022-11-15 | Boston Scientific Neuromodulation Corporation | Systems and methods for making and using an electrical stimulation system with a case-neutral battery |
US10702692B2 (en) | 2018-03-02 | 2020-07-07 | Aleva Neurotherapeutics | Neurostimulation device |
US11058870B2 (en) | 2018-03-09 | 2021-07-13 | Boston Scientific Neuromodulation Corporation | Burr hole plugs for electrical stimulation systems and methods of making and using |
US11013913B2 (en) | 2018-03-16 | 2021-05-25 | Boston Scientific Neuromodulation Corporation | Kits and methods for securing a burr hole plugs for stimulation systems |
CN111886050A (en) | 2018-03-21 | 2020-11-03 | 美敦力公司 | Implantable medical device structure including a recharging and/or telemetry coil |
CN111886046A (en) | 2018-03-23 | 2020-11-03 | 美敦力公司 | AV-synchronized VFA cardiac therapy |
CN111902187A (en) | 2018-03-23 | 2020-11-06 | 美敦力公司 | VFA cardiac resynchronization therapy |
US11058880B2 (en) | 2018-03-23 | 2021-07-13 | Medtronic, Inc. | VFA cardiac therapy for tachycardia |
US11253708B2 (en) | 2018-05-24 | 2022-02-22 | Medtronic, Inc. | Machined features of enclosures for implantable medical devices |
CN112770807A (en) | 2018-09-26 | 2021-05-07 | 美敦力公司 | Capture in atrial-to-ventricular cardiac therapy |
US11247059B2 (en) | 2018-11-20 | 2022-02-15 | Pacesetter, Inc. | Biostimulator having flexible circuit assembly |
WO2020104888A1 (en) | 2018-11-21 | 2020-05-28 | Biosense Webster (Israel) Ltd. | Ablation catheter with stacked circuit assembly |
US20200222703A1 (en) * | 2019-01-10 | 2020-07-16 | Stimwave Technologies Incorporated | Wireless implantable pulse generators |
US11471683B2 (en) | 2019-01-29 | 2022-10-18 | Synapse Biomedical, Inc. | Systems and methods for treating sleep apnea using neuromodulation |
US11058882B2 (en) | 2019-02-11 | 2021-07-13 | Medtronic, Inc. | Implantable medical devices having circuitry located adjacent to header-related structures |
US11679265B2 (en) | 2019-02-14 | 2023-06-20 | Medtronic, Inc. | Lead-in-lead systems and methods for cardiac therapy |
US11697025B2 (en) | 2019-03-29 | 2023-07-11 | Medtronic, Inc. | Cardiac conduction system capture |
US11213676B2 (en) | 2019-04-01 | 2022-01-04 | Medtronic, Inc. | Delivery systems for VfA cardiac therapy |
US20200338325A1 (en) * | 2019-04-29 | 2020-10-29 | Cognos Theraeutics Inc | Method and apparatus for a long-term, fully implantable mri compatible drug pump |
US11712188B2 (en) | 2019-05-07 | 2023-08-01 | Medtronic, Inc. | Posterior left bundle branch engagement |
US11305127B2 (en) | 2019-08-26 | 2022-04-19 | Medtronic Inc. | VfA delivery and implant region detection |
US11813466B2 (en) | 2020-01-27 | 2023-11-14 | Medtronic, Inc. | Atrioventricular nodal stimulation |
US11911168B2 (en) | 2020-04-03 | 2024-02-27 | Medtronic, Inc. | Cardiac conduction system therapy benefit determination |
US11813464B2 (en) | 2020-07-31 | 2023-11-14 | Medtronic, Inc. | Cardiac conduction system evaluation |
US11400299B1 (en) | 2021-09-14 | 2022-08-02 | Rainbow Medical Ltd. | Flexible antenna for stimulator |
WO2023049145A1 (en) * | 2021-09-22 | 2023-03-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Implantable cranial electronics |
WO2023152131A1 (en) * | 2022-02-11 | 2023-08-17 | Biotronik Se & Co. Kg | Active implantable medical device comprising a film-like connecting element |
Citations (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3720874A (en) * | 1971-11-08 | 1973-03-13 | Motorola Inc | Dipole antenna arrangement for radio with separate speaker-microphone assembly |
US3888260A (en) * | 1972-06-28 | 1975-06-10 | Univ Johns Hopkins | Rechargeable demand inhibited cardiac pacer and tissue stimulator |
US4010760A (en) * | 1975-05-23 | 1977-03-08 | Medtronic, Inc. | Coupling assembly for implantable electromedical devices |
US4013081A (en) * | 1976-04-19 | 1977-03-22 | Arco Medical Products Company | Pediatric cardiac pacer system |
US4040412A (en) * | 1974-08-09 | 1977-08-09 | Sato Takuya R | Bioelectrodes |
US4094321A (en) * | 1977-02-07 | 1978-06-13 | Rudolph Muto | Shallow, dome-shaped pacer with bottom storage means for catheter |
US4256115A (en) * | 1976-12-20 | 1981-03-17 | American Technology, Inc. | Leadless cardiac pacer |
US4266552A (en) * | 1979-11-13 | 1981-05-12 | Medtronic, Inc. | Lead anchoring bobbin |
US4328813A (en) * | 1980-10-20 | 1982-05-11 | Medtronic, Inc. | Brain lead anchoring system |
US4399820A (en) * | 1981-02-26 | 1983-08-23 | Alexander Wirtzfeld | Process and device for regulating the stimulation frequency of heart pacemakers |
US4499907A (en) * | 1982-11-15 | 1985-02-19 | Medtronic, Inc. | Energy limiting cardioversion lead |
US4911178A (en) * | 1988-06-02 | 1990-03-27 | Neal Carol A | Pacemaker wire dressing |
US4928696A (en) * | 1989-07-26 | 1990-05-29 | Mindcenter Corporation | Electrode-supporting headset |
US4934368A (en) * | 1988-01-21 | 1990-06-19 | Myo/Kinetics Systems, Inc. | Multi-electrode neurological stimulation apparatus |
US5085644A (en) * | 1990-04-02 | 1992-02-04 | Pudenz-Schulte Medical Research Corporation | Sterilizable medication infusion device with dose recharge restriction |
US5116345A (en) * | 1990-11-28 | 1992-05-26 | Ohio Medical Instrument Co., Inc. | Stereotactically implanting an intracranial device |
US5197332A (en) * | 1992-02-19 | 1993-03-30 | Calmed Technology, Inc. | Headset hearing tester and hearing aid programmer |
US5312440A (en) * | 1991-03-28 | 1994-05-17 | Siemens Aktiengesellschaft | Implantable defibrillator arrangement |
US5314453A (en) * | 1991-12-06 | 1994-05-24 | Spinal Cord Society | Position sensitive power transfer antenna |
US5314451A (en) * | 1993-01-15 | 1994-05-24 | Medtronic, Inc. | Replaceable battery for implantable medical device |
USH1465H (en) * | 1993-09-08 | 1995-07-04 | Medtronic, Inc. | Implantable lead infection barrier |
US5433734A (en) * | 1992-05-06 | 1995-07-18 | Medtronic, Inc. | Tool-less threaded connector assembly |
US5480416A (en) * | 1994-09-22 | 1996-01-02 | Intermedics, Inc. | Cardiac pacemaker with universal coating |
US5489225A (en) * | 1993-12-16 | 1996-02-06 | Ventritex, Inc. | Electrical terminal with a collet grip for a defibrillator |
US5613935A (en) * | 1994-12-16 | 1997-03-25 | Jarvik; Robert | High reliability cardiac assist system |
US5638832A (en) * | 1995-06-07 | 1997-06-17 | Interval Research Corporation | Programmable subcutaneous visible implant |
US5645586A (en) * | 1994-07-08 | 1997-07-08 | Ventritex, Inc. | Conforming implantable defibrillator |
US5741313A (en) * | 1996-09-09 | 1998-04-21 | Pacesetter, Inc. | Implantable medical device with a reduced volumetric configuration and improved shock stabilization |
US5755743A (en) * | 1996-06-05 | 1998-05-26 | Implex Gmbh Spezialhorgerate | Implantable unit |
US5769874A (en) * | 1996-03-26 | 1998-06-23 | Pacesetter Ab | Active medical implant with a hermetically sealed capsule |
US5776169A (en) * | 1997-04-28 | 1998-07-07 | Sulzer Intermedics Inc. | Implantable cardiac stimulator for minimally invasive implantation |
US5873899A (en) * | 1996-01-16 | 1999-02-23 | Pacesetter Inc. | Implantable medical device having compliant support for internal components |
US5876424A (en) * | 1997-01-23 | 1999-03-02 | Cardiac Pacemakers, Inc. | Ultra-thin hermetic enclosure for implantable medical devices |
US5896647A (en) * | 1994-09-09 | 1999-04-27 | Nec Moli Energy (Canada) Limited | Sealed electrical device with unitary fill port and terminal construction |
US5919215A (en) * | 1997-08-01 | 1999-07-06 | Medtronic, Inc. | Attachment apparatus for an implantable medical device employing ultrasonic energy |
US5935154A (en) * | 1997-01-24 | 1999-08-10 | Cardiac Pacemakers, Inc. | Implantable tissue stimulator incorporating deposited multilayer capacitor |
US5941906A (en) * | 1997-10-15 | 1999-08-24 | Medtronic, Inc. | Implantable, modular tissue stimulator |
US5941905A (en) * | 1997-09-29 | 1999-08-24 | Cochlear Limited | Public alarm for cochlear implant |
US6016449A (en) * | 1997-10-27 | 2000-01-18 | Neuropace, Inc. | System for treatment of neurological disorders |
US6016593A (en) * | 1998-04-10 | 2000-01-25 | Kyrstein Investments Ltd. | Electric drive system for planer mill infeed and outfeed rolls |
US6044304A (en) * | 1998-04-29 | 2000-03-28 | Medtronic, Inc. | Burr ring with integral lead/catheter fixation device |
US6067474A (en) * | 1997-08-01 | 2000-05-23 | Advanced Bionics Corporation | Implantable device with improved battery recharging and powering configuration |
US6091979A (en) * | 1998-07-07 | 2000-07-18 | Children's Medical Center Corporation | Subdural electrode arrays for monitoring cortical electrical activity |
US6168580B1 (en) * | 1999-03-26 | 2001-01-02 | Iontophoretics Corporation | Antimicrobial device and methods for long-term catheters |
US6176879B1 (en) * | 1998-07-02 | 2001-01-23 | Implex Aktienegesellschaft Hearing Technology | Medical implant |
US6205358B1 (en) * | 1997-08-01 | 2001-03-20 | Medtronic, Inc. | Method of making ultrasonically welded, staked of swaged components in an implantable medical device |
US6214032B1 (en) * | 1996-02-20 | 2001-04-10 | Advanced Bionics Corporation | System for implanting a microstimulator |
US6218016B1 (en) * | 1998-09-29 | 2001-04-17 | Medtronic Ave, Inc. | Lubricious, drug-accommodating coating |
US6230049B1 (en) * | 1999-08-13 | 2001-05-08 | Neuro Pace, Inc. | Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes |
US6248080B1 (en) * | 1997-09-03 | 2001-06-19 | Medtronic, Inc. | Intracranial monitoring and therapy delivery control device, system and method |
US6259951B1 (en) * | 1999-05-14 | 2001-07-10 | Advanced Bionics Corporation | Implantable cochlear stimulator system incorporating combination electrode/transducer |
US6263225B1 (en) * | 1994-02-09 | 2001-07-17 | University Of Iowa Research Foundation | Stereotactic electrode assembly |
US6266556B1 (en) * | 1998-04-27 | 2001-07-24 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation |
US20020013612A1 (en) * | 2000-06-20 | 2002-01-31 | Whitehurst Todd K. | System and method for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion |
US20020019669A1 (en) * | 1999-11-29 | 2002-02-14 | Epic Biosonics Inc. | Totally implantable cochlear prosthesis |
US6354299B1 (en) * | 1997-10-27 | 2002-03-12 | Neuropace, Inc. | Implantable device for patient communication |
US6356792B1 (en) * | 2000-01-20 | 2002-03-12 | Electro Core Technologies, Llc | Skull mounted electrode lead securing assembly |
US6366813B1 (en) * | 1998-08-05 | 2002-04-02 | Dilorenzo Daniel J. | Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease |
US20020042634A1 (en) * | 2000-09-18 | 2002-04-11 | Cameron Health, Inc. | Ceramics and/or other material insulated shell for active and non-active S-ICD can |
US20020051550A1 (en) * | 2000-08-25 | 2002-05-02 | Hans Leysieffer | Implantable hermetically sealed housing for an implantable medical device and process for producing the same |
US20020068958A1 (en) * | 2000-09-18 | 2002-06-06 | Cameron Health, Inc. | Radian curve shaped implantable cardioverter-defibrillator canister |
US6405079B1 (en) * | 2000-09-22 | 2002-06-11 | Mehdi M. Ansarinia | Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions |
US20020087201A1 (en) * | 2000-07-13 | 2002-07-04 | Firlik Andrew D. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US6427086B1 (en) * | 1997-10-27 | 2002-07-30 | Neuropace, Inc. | Means and method for the intracranial placement of a neurostimulator |
US20030004546A1 (en) * | 2000-08-29 | 2003-01-02 | Casey Don E. | Subcutaneously implantable power supply |
US20030004428A1 (en) * | 2001-06-28 | 2003-01-02 | Pless Benjamin D. | Seizure sensing and detection using an implantable device |
US6516227B1 (en) * | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
US6517476B1 (en) * | 2000-05-30 | 2003-02-11 | Otologics Llc | Connector for implantable hearing aid |
US6537200B2 (en) * | 2000-03-28 | 2003-03-25 | Cochlear Limited | Partially or fully implantable hearing system |
US20030073972A1 (en) * | 2000-04-05 | 2003-04-17 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
US6554762B2 (en) * | 2000-08-25 | 2003-04-29 | Cochlear Limited | Implantable hearing system with means for measuring its coupling quality |
US6560486B1 (en) * | 1999-10-12 | 2003-05-06 | Ivan Osorio | Bi-directional cerebral interface system |
US20030085684A1 (en) * | 2001-11-07 | 2003-05-08 | Quallion Llc | Implantable medical power module |
US6567703B1 (en) * | 2000-11-08 | 2003-05-20 | Medtronic, Inc. | Implantable medical device incorporating miniaturized circuit module |
US6565503B2 (en) * | 2000-04-13 | 2003-05-20 | Cochlear Limited | At least partially implantable system for rehabilitation of hearing disorder |
US6575894B2 (en) * | 2000-04-13 | 2003-06-10 | Cochlear Limited | At least partially implantable system for rehabilitation of a hearing disorder |
US20030109903A1 (en) * | 2001-12-12 | 2003-06-12 | Epic Biosonics Inc. | Low profile subcutaneous enclosure |
US20030120320A1 (en) * | 2001-12-20 | 2003-06-26 | Medtronic,Inc. | Implantable medical device having a housing or component case with an insulating material formed thereon, and methods of making same |
US20030125786A1 (en) * | 2000-07-13 | 2003-07-03 | Gliner Bradford Evan | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US20030130706A1 (en) * | 2000-07-13 | 2003-07-10 | Sheffield W. Douglas | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US6597954B1 (en) * | 1997-10-27 | 2003-07-22 | Neuropace, Inc. | System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes |
US6726678B1 (en) * | 2001-02-22 | 2004-04-27 | Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
US20040082977A1 (en) * | 2002-10-25 | 2004-04-29 | Engmark David B. | Implantable medical device with air core antenna assembly |
US20040102828A1 (en) * | 2002-11-27 | 2004-05-27 | Lowry David Warren | Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography |
US20050033378A1 (en) * | 2002-12-09 | 2005-02-10 | Sheffield Warren Douglas | Methods for treating and/or collecting information regarding neurological disorders, including language disorders |
US20050070971A1 (en) * | 2003-08-01 | 2005-03-31 | Brad Fowler | Apparatus and methods for applying neural stimulation to a patient |
US20050075679A1 (en) * | 2002-09-30 | 2005-04-07 | Gliner Bradford E. | Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system |
US6882881B1 (en) * | 1999-10-19 | 2005-04-19 | The Johns Hopkins University | Techniques using heat flow management, stimulation, and signal analysis to treat medical disorders |
US6899976B2 (en) * | 2000-10-13 | 2005-05-31 | Medtronic Inc | Feed through assembly for a formable flat battery |
US20060116743A1 (en) * | 2002-08-09 | 2006-06-01 | Peter Gibson | Fixation system for an implantable medical device |
US20060129205A1 (en) * | 1998-10-26 | 2006-06-15 | Boveja Birinder R | Method and system for cortical stimulation with rectangular and/or complex electrical pulses to provide therapy for stroke and other neurological disorders |
US7212864B2 (en) * | 2002-12-09 | 2007-05-01 | Medtronic, Inc. | Modular implantable medical device |
Family Cites Families (145)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US656503A (en) * | 1900-04-28 | 1900-08-21 | American Dredging Company | Hydraulic dredging apparatus. |
US3310051A (en) | 1963-12-10 | 1967-03-21 | Rudolf R Schulte | Surgical reservoir for implantation beneath the skin |
FR1516654A (en) * | 1966-03-25 | 1968-03-08 | Chirana Zd Y Zdravotnickej Tec | Implantable cardio-stimulator |
DE1589587A1 (en) | 1966-03-25 | 1970-04-30 | Chirana Zd Y Zdravotnickej Ech | Implantable cardiac stimulator |
US3522811A (en) | 1969-02-13 | 1970-08-04 | Medtronic Inc | Implantable nerve stimulator and method of use |
DE2053728C3 (en) | 1969-11-03 | 1980-03-06 | Devices Ltd., Welwyn Garden City, Hertfordshire (Ver. Koenigreich) | Implantable electrical device and method of making the same |
US3724467A (en) * | 1971-04-23 | 1973-04-03 | Avery Labor Inc | Electrode implant for the neuro-stimulation of the spinal cord |
US3913587A (en) * | 1973-12-10 | 1975-10-21 | Dow Corning | Implantable extendable member |
DE2415385A1 (en) | 1974-03-29 | 1975-10-02 | Siemens Ag | PACEMAKER |
US3926198A (en) | 1974-06-10 | 1975-12-16 | Arco Med Prod Co | Cardiac pacer |
US4006748A (en) | 1976-01-29 | 1977-02-08 | Pacestter Systems, Inc. | Implantable unipolar pacemaker with improved outer electrode plate |
US4408607A (en) | 1981-04-13 | 1983-10-11 | Empi, Inc. | Capacitive energy source and circuitry for powering medical apparatus |
US4399819A (en) * | 1981-12-21 | 1983-08-23 | Telectronics Pty. Ltd. | Heart pacer mechanical construction |
US4503860A (en) | 1983-03-31 | 1985-03-12 | Bio-Scan, Inc. | Electroencephalography electrode assembly |
US4616655A (en) * | 1984-01-20 | 1986-10-14 | Cordis Corporation | Implantable pulse generator having a single printed circuit board and a chip carrier |
US4574780A (en) | 1984-11-13 | 1986-03-11 | Manders Ernest K | Tissue expander and method |
US5251127A (en) | 1988-02-01 | 1993-10-05 | Faro Medical Technologies Inc. | Computer-aided surgery apparatus |
US4972846A (en) * | 1989-01-31 | 1990-11-27 | W. L. Gore & Associates, Inc. | Patch electrodes for use with defibrillators |
US4969899A (en) | 1989-03-08 | 1990-11-13 | Cox-Uphoff International | Inflatable implant |
DE3940632C1 (en) | 1989-06-02 | 1990-12-06 | Hortmann Gmbh, 7449 Neckartenzlingen, De | Hearing aid directly exciting inner ear - has microphone encapsulated for implantation in tympanic cavity or mastoid region |
US5396813A (en) | 1989-08-31 | 1995-03-14 | Nikkiso Company Limited | Gas passage shifting device |
US5271397A (en) | 1989-09-08 | 1993-12-21 | Cochlear Pty. Ltd. | Multi-peak speech processor |
US5218959A (en) | 1990-10-03 | 1993-06-15 | Fenster Harold A | Body implantable electrical signal generator with redundant lead retainer and surgical procedure |
US5207218A (en) | 1991-02-27 | 1993-05-04 | Medtronic, Inc. | Implantable pulse generator |
US5954757A (en) | 1991-05-17 | 1999-09-21 | Gray; Noel Desmond | Heart pacemaker |
US5368832A (en) * | 1991-06-07 | 1994-11-29 | Occidental Chemical Corporation | Zero discharge process for manufacturing of phosphorous acid and hypophosphorous acid |
US5243977A (en) * | 1991-06-26 | 1993-09-14 | Trabucco Hector O | Pacemaker |
US5144946A (en) | 1991-08-05 | 1992-09-08 | Siemens Pacesetter, Inc. | Combined pacemaker substrate and electrical interconnect and method of assembly |
EP0534782A1 (en) | 1991-09-26 | 1993-03-31 | Medtronic, Inc. | Implantable medical device enclosure |
US5220929A (en) | 1991-10-02 | 1993-06-22 | Ventritex, Inc. | Bio-compatible boot for implantable medical device |
US5603318A (en) | 1992-04-21 | 1997-02-18 | University Of Utah Research Foundation | Apparatus and method for photogrammetric surgical localization |
US5676651A (en) | 1992-08-06 | 1997-10-14 | Electric Boat Corporation | Surgically implantable pump arrangement and method for pumping body fluids |
US5252090A (en) | 1992-09-30 | 1993-10-12 | Telectronics Pacing Systems, Inc. | Self-locking implantable stimulating lead connector |
US5284161A (en) * | 1992-11-12 | 1994-02-08 | Karell Manuel L | Snopper-the snoring stopper anti-snoring mouth device |
US5531787A (en) | 1993-01-25 | 1996-07-02 | Lesinski; S. George | Implantable auditory system with micromachined microsensor and microactuator |
US5477855A (en) | 1993-07-16 | 1995-12-26 | Alfred E. Mann Foundation For Scientific Research | Shield for conductors of an implantable device |
US5411537A (en) * | 1993-10-29 | 1995-05-02 | Intermedics, Inc. | Rechargeable biomedical battery powered devices with recharging and control system therefor |
US5411538A (en) | 1993-11-01 | 1995-05-02 | Intermedics, Inc. | Implantable medical device with detachable battery or electronic circuit |
US5573551A (en) | 1993-11-01 | 1996-11-12 | Intermedics, Inc. | Implantable medical device with detachable battery or electronic circuit |
US5431695A (en) | 1993-11-23 | 1995-07-11 | Medtronic, Inc. | Pacemaker |
US5800535A (en) * | 1994-02-09 | 1998-09-01 | The University Of Iowa Research Foundation | Wireless prosthetic electrode for the brain |
US5697975A (en) | 1994-02-09 | 1997-12-16 | The University Of Iowa Research Foundation | Human cerebral cortex neural prosthetic for tinnitus |
US5419977A (en) | 1994-03-09 | 1995-05-30 | Medtronic, Inc. | Electrochemical device having operatively combined capacitor |
US5571148A (en) | 1994-08-10 | 1996-11-05 | Loeb; Gerald E. | Implantable multichannel stimulator |
US5458997A (en) | 1994-08-19 | 1995-10-17 | Medtronic, Inc. | Rebalancing of lithium/silver vandium oxide (Li/SVO) cells for improved performance |
WO1996014834A1 (en) | 1994-11-10 | 1996-05-23 | University Of Kentucky Research Foundation | Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body |
US5562715A (en) | 1994-12-01 | 1996-10-08 | Czura; John J. | Cardiac pulse generator |
US5678559A (en) | 1995-01-23 | 1997-10-21 | Drakulic; Budimir S. | Eeg system |
US5554194A (en) | 1995-06-07 | 1996-09-10 | United States Surgical Corporation | Modular surgical implant |
US20020169485A1 (en) | 1995-10-16 | 2002-11-14 | Neuropace, Inc. | Differential neurostimulation therapy driven by physiological context |
US6480743B1 (en) * | 2000-04-05 | 2002-11-12 | Neuropace, Inc. | System and method for adaptive brain stimulation |
US6944501B1 (en) | 2000-04-05 | 2005-09-13 | Neurospace, Inc. | Neurostimulator involving stimulation strategies and process for using it |
US6558686B1 (en) | 1995-11-08 | 2003-05-06 | Baylor College Of Medicine | Method of coating medical devices with a combination of antiseptics and antiseptic coating therefor |
US5792067A (en) | 1995-11-21 | 1998-08-11 | Karell; Manuel L. | Apparatus and method for mitigating sleep and other disorders through electromuscular stimulation |
US5674260A (en) * | 1996-02-23 | 1997-10-07 | Pacesetter, Inc. | Apparatus and method for mounting an activity sensor or other component within a pacemaker using a contoured hybrid lid |
US5895414A (en) * | 1996-04-19 | 1999-04-20 | Sanchez-Zambrano; Sergio | Pacemaker housing |
US5814095A (en) | 1996-09-18 | 1998-09-29 | Implex Gmbh Spezialhorgerate | Implantable microphone and implantable hearing aids utilizing same |
US5830137A (en) * | 1996-11-18 | 1998-11-03 | University Of South Florida | Green light pulse oximeter |
WO1998030603A1 (en) * | 1997-01-14 | 1998-07-16 | Dsm N.V. | A process for polymerizing olefins |
US5991664A (en) | 1997-03-09 | 1999-11-23 | Cochlear Limited | Compact inductive arrangement for medical implant data and power transfer |
FR2765486B1 (en) | 1997-07-03 | 1999-10-01 | Ela Medical Sa | SYSTEM FOR THE MECHANICAL IMMOBILIZATION OF A PROBE CONNECTOR IN AN ACTIVE IMPLANTABLE MEDICAL DEVICE GENERATOR CONNECTOR, IN PARTICULAR FOR A HEART STIMULATOR, DEFIBRILLATOR AND / OR CARDIOVERTER |
US6516808B2 (en) | 1997-09-12 | 2003-02-11 | Alfred E. Mann Foundation For Scientific Research | Hermetic feedthrough for an implantable device |
US5843150A (en) | 1997-10-08 | 1998-12-01 | Medtronic, Inc. | System and method for providing electrical and/or fluid treatment within a patient's brain |
US6647296B2 (en) | 1997-10-27 | 2003-11-11 | Neuropace, Inc. | Implantable apparatus for treating neurological disorders |
US6459936B2 (en) | 1997-10-27 | 2002-10-01 | Neuropace, Inc. | Methods for responsively treating neurological disorders |
US6248126B1 (en) | 1998-01-12 | 2001-06-19 | The Johns Hopkins University | Technique for using heat flow management to treat brain disorders |
US5954751A (en) | 1998-01-15 | 1999-09-21 | Intermedics Inc. | Implantable defibrillator with stacked transistor subassemblies |
US5958088A (en) | 1998-03-04 | 1999-09-28 | Duracell, Inc. | Prismatic cell construction |
US6421566B1 (en) | 1998-04-30 | 2002-07-16 | Medtronic, Inc. | Selective dorsal column stimulation in SCS, using conditioning pulses |
US5938689A (en) | 1998-05-01 | 1999-08-17 | Neuropace, Inc. | Electrode configuration for a brain neuropacemaker |
US6006124A (en) | 1998-05-01 | 1999-12-21 | Neuropace, Inc. | Means and method for the placement of brain electrodes |
DE19827898C1 (en) * | 1998-06-23 | 1999-11-11 | Hans Leysieffer | Electrical energy supply for an implant, eg. a hearing aid |
US6308101B1 (en) * | 1998-07-31 | 2001-10-23 | Advanced Bionics Corporation | Fully implantable cochlear implant system |
US6272382B1 (en) | 1998-07-31 | 2001-08-07 | Advanced Bionics Corporation | Fully implantable cochlear implant system |
DE19837912C1 (en) * | 1998-08-20 | 1999-10-28 | Implex Hear Tech Ag | Energy supply module for implanted device e.g. hearing aid or tinnitus masking device, heart pacemaker or drug dispenser |
DE19837913C2 (en) | 1998-08-20 | 2000-09-28 | Implex Hear Tech Ag | Implantable device with a charging current feed arrangement having a receiving coil |
US6283997B1 (en) | 1998-11-13 | 2001-09-04 | The Trustees Of Princeton University | Controlled architecture ceramic composites by stereolithography |
US6436422B1 (en) | 1998-11-23 | 2002-08-20 | Agion Technologies L.L.C. | Antibiotic hydrophilic polymer coating |
US6052623A (en) | 1998-11-30 | 2000-04-18 | Medtronic, Inc. | Feedthrough assembly for implantable medical devices and methods for providing same |
US6415184B1 (en) | 1999-01-06 | 2002-07-02 | Ball Semiconductor, Inc. | Implantable neuro-stimulator with ball implant |
US6106464A (en) | 1999-02-22 | 2000-08-22 | Vanderbilt University | Apparatus and method for bone surface-based registration of physical space with tomographic images and for guiding an instrument relative to anatomical sites in the image |
US6324428B1 (en) | 1999-03-30 | 2001-11-27 | Pacesetter, Inc. | Implantable medical device having an improved electronic assembly for increasing packaging density and enhancing component protection |
US6233488B1 (en) | 1999-06-25 | 2001-05-15 | Carl A. Hess | Spinal cord stimulation as a treatment for addiction to nicotine and other chemical substances |
US6327502B1 (en) | 1999-08-16 | 2001-12-04 | Pacesetter Ab | Implantable stimulator housing with electrode connector |
US6241032B1 (en) * | 1999-09-07 | 2001-06-05 | Thomas E. Falgout, Sr. | One-way drill string clutch |
US6445956B1 (en) | 1999-10-18 | 2002-09-03 | Abiomed, Inc. | Implantable medical device |
US7702380B1 (en) | 1999-11-03 | 2010-04-20 | Case Western Reserve University | System and method for producing a three-dimensional model |
US6324433B1 (en) | 2000-01-20 | 2001-11-27 | Electrocare Technologies, Llc | Electrode-lead coupling skull mounted port assembly |
US6920359B2 (en) | 2000-02-15 | 2005-07-19 | Advanced Bionics Corporation | Deep brain stimulation system for the treatment of Parkinson's Disease or other disorders |
US6627337B2 (en) | 2000-02-16 | 2003-09-30 | Wilson Greatbatch Ltd. | Conversion of low rate energy into high rate energy by parallel discharging |
DE60126779T2 (en) | 2000-03-24 | 2007-12-13 | Cymbet Corp., Elk River | MANUFACTURE AT LOW TEMPERATURE OF THIN-LAYERED ENERGY STORAGE DEVICES |
US6466822B1 (en) * | 2000-04-05 | 2002-10-15 | Neuropace, Inc. | Multimodal neurostimulator and process of using it |
US6772026B2 (en) | 2000-04-05 | 2004-08-03 | Therics, Inc. | System and method for rapidly customizing design, manufacture and/or selection of biomedical devices |
US6490486B1 (en) | 2000-04-27 | 2002-12-03 | Pacesetter, Inc. | Implantable cardiac stimulation device and method that monitors displacement of an implanted lead |
US6610067B2 (en) | 2000-05-01 | 2003-08-26 | Arthrosurface, Incorporated | System and method for joint resurface repair |
US20040028977A1 (en) * | 2000-05-30 | 2004-02-12 | Peter Pickup | Fuel cell incorporating a modified ion exchange membrane |
US6505077B1 (en) | 2000-06-19 | 2003-01-07 | Medtronic, Inc. | Implantable medical device with external recharging coil electrical connection |
WO2002005590A1 (en) | 2000-06-30 | 2002-01-17 | Cochlear Limited | Cochlear implant |
JP2002017652A (en) * | 2000-06-30 | 2002-01-22 | Olympus Optical Co Ltd | Endoscope |
DE10041728A1 (en) * | 2000-08-25 | 2002-03-21 | Implex Hear Tech Ag | Implantable medicinal device with hermetically sealed housing has storage device accommodated directly within hermetically sealed housing without housing of its own |
US7120495B2 (en) * | 2000-09-18 | 2006-10-10 | Cameron Health, Inc. | Flexible subcutaneous implantable cardioverter-defibrillator |
US6950705B2 (en) | 2000-09-18 | 2005-09-27 | Cameron Health, Inc. | Canister designs for implantable cardioverter-defibrillators |
US7194309B2 (en) | 2000-09-18 | 2007-03-20 | Cameron Health, Inc. | Packaging technology for non-transvenous cardioverter/defibrillator devices |
US6618623B1 (en) * | 2000-11-28 | 2003-09-09 | Neuropace, Inc. | Ferrule for cranial implant |
US7033326B1 (en) * | 2000-12-29 | 2006-04-25 | Advanced Bionics Corporation | Systems and methods of implanting a lead for brain stimulation |
US7630750B2 (en) | 2001-02-05 | 2009-12-08 | The Research Foundation For The State University Of New York | Computer aided treatment planning |
US7069081B2 (en) | 2001-02-08 | 2006-06-27 | Wilson Greatbatch Ltd. | One piece header assembly for an implantable medical device |
US20020116028A1 (en) * | 2001-02-20 | 2002-08-22 | Wilson Greatbatch | MRI-compatible pacemaker with pulse carrying photonic catheter providing VOO functionality |
US7299096B2 (en) | 2001-03-08 | 2007-11-20 | Northstar Neuroscience, Inc. | System and method for treating Parkinson's Disease and other movement disorders |
US6622046B2 (en) | 2001-05-07 | 2003-09-16 | Medtronic, Inc. | Subcutaneous sensing feedthrough/electrode assembly |
US6671544B2 (en) | 2001-06-28 | 2003-12-30 | Medtronic, Inc. | Low impedance implantable extension for a neurological electrical stimulator |
JP4377570B2 (en) * | 2001-07-19 | 2009-12-02 | グレイトバッチ リミテッド | Casing with outer shell for electrochemical cell |
US6977124B2 (en) * | 2001-07-19 | 2005-12-20 | Wilson Greatbatch Technologies, Inc. | Contoured casing for an electrochemical cell |
US6456256B1 (en) | 2001-08-03 | 2002-09-24 | Cardiac Pacemakers, Inc. | Circumferential antenna for an implantable medical device |
US6721602B2 (en) | 2001-08-21 | 2004-04-13 | Medtronic, Inc. | Implantable medical device assembly and manufacturing method |
US6626680B2 (en) * | 2001-08-24 | 2003-09-30 | Wilson Greatbatch Ltd. | Wire bonding surface |
US7070881B2 (en) | 2001-10-18 | 2006-07-04 | Quallion Llc | Electrical battery assembly and method of manufacture |
US6788976B2 (en) * | 2001-11-02 | 2004-09-07 | Lockheed Martin Corporation | Movement timing simulator |
US6963780B2 (en) | 2002-01-31 | 2005-11-08 | Medtronic, Inc. | Implantable medical device including a surface-mount terminal array |
US7110819B1 (en) | 2002-03-05 | 2006-09-19 | Pacesetter, Inc. | Implantable medical device having a protected connection header |
US7747311B2 (en) | 2002-03-06 | 2010-06-29 | Mako Surgical Corp. | System and method for interactive haptic positioning of a medical device |
AU2003224997A1 (en) | 2002-04-16 | 2003-11-03 | Michael Conditt | Computer-based training methods for surgical procedures |
US6968234B2 (en) | 2002-04-25 | 2005-11-22 | Medtronic, Inc. | Implantable medical device having biologically active polymeric casing |
US20030228042A1 (en) | 2002-06-06 | 2003-12-11 | Usha Sinha | Method and system for preparation of customized imaging atlas and registration with patient images |
US6994933B1 (en) * | 2002-09-16 | 2006-02-07 | Oak Ridge Micro-Energy, Inc. | Long life thin film battery and method therefor |
WO2004043536A1 (en) | 2002-11-12 | 2004-05-27 | Neuropace, Inc. | System for adaptive brain stimulation |
US7596408B2 (en) | 2002-12-09 | 2009-09-29 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US20040186528A1 (en) | 2003-03-20 | 2004-09-23 | Medtronic, Inc. | Subcutaneous implantable medical devices with anti-microbial agents for chronic release |
EP1624921A4 (en) * | 2003-04-28 | 2008-12-31 | Univ Vanderbilt | Apparatus and methods of optimal placement of deep brain stimulator |
US20050004637A1 (en) * | 2003-05-16 | 2005-01-06 | Ruchika Singhal | Explantation of implantable medical device |
US7263401B2 (en) | 2003-05-16 | 2007-08-28 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US7317947B2 (en) | 2003-05-16 | 2008-01-08 | Medtronic, Inc. | Headset recharger for cranially implantable medical devices |
US20050003268A1 (en) | 2003-05-16 | 2005-01-06 | Scott Erik R. | Battery housing configuration |
US7454251B2 (en) | 2003-05-29 | 2008-11-18 | The Cleveland Clinic Foundation | Excess lead retaining and management devices and methods of using same |
EP1638459A2 (en) * | 2003-06-11 | 2006-03-29 | Case Western Reserve University | Computer-aided-design of skeletal implants |
WO2005051479A2 (en) | 2003-11-20 | 2005-06-09 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation system and method for treating tinnitus |
US7107097B2 (en) | 2004-01-14 | 2006-09-12 | Northstar Neuroscience, Inc. | Articulated neural electrode assembly |
JP4408708B2 (en) * | 2004-01-14 | 2010-02-03 | 株式会社島精機製作所 | Knitting pant knitting method, knitting pant, and knitting program for causing flat knitting machine to knit pants |
WO2005087314A1 (en) * | 2004-03-11 | 2005-09-22 | Advanced Neuromodulation Systems, Inc. | Brain stimulation system and method |
US7283856B2 (en) | 2004-04-09 | 2007-10-16 | Neuro Pace, Inc. | Implantable lead system with seed electrodes |
US7596399B2 (en) | 2004-04-29 | 2009-09-29 | Medtronic, Inc | Implantation of implantable medical device |
US20050245984A1 (en) | 2004-04-30 | 2005-11-03 | Medtronic, Inc. | Implantable medical device with lubricious material |
US7783359B2 (en) | 2005-01-05 | 2010-08-24 | Boston Scientific Neuromodulation Corporation | Devices and methods using an implantable pulse generator for brain stimulation |
US9084901B2 (en) | 2006-04-28 | 2015-07-21 | Medtronic, Inc. | Cranial implant |
US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
-
2003
- 2003-12-09 DE DE60332764T patent/DE60332764D1/en not_active Expired - Lifetime
- 2003-12-09 EP EP03787284A patent/EP1578493A1/en not_active Withdrawn
- 2003-12-09 WO PCT/US2003/038981 patent/WO2004052458A1/en not_active Application Discontinuation
- 2003-12-09 WO PCT/US2003/038982 patent/WO2004052459A1/en not_active Application Discontinuation
- 2003-12-09 DE DE60332272T patent/DE60332272D1/en not_active Expired - Lifetime
- 2003-12-09 EP EP03812860A patent/EP1578500A1/en not_active Withdrawn
- 2003-12-09 EP EP03796788A patent/EP1578496A1/en not_active Withdrawn
- 2003-12-09 WO PCT/US2003/038939 patent/WO2004052456A1/en not_active Application Discontinuation
- 2003-12-09 EP EP03787285A patent/EP1578494B1/en not_active Expired - Lifetime
- 2003-12-09 US US10/730,873 patent/US7242982B2/en not_active Expired - Lifetime
- 2003-12-09 EP EP03796790A patent/EP1578498A1/en not_active Withdrawn
- 2003-12-09 US US10/731,638 patent/US7212864B2/en not_active Expired - Lifetime
- 2003-12-09 EP EP03790404A patent/EP1578495B1/en not_active Expired - Lifetime
- 2003-12-09 AU AU2003293454A patent/AU2003293454A1/en not_active Abandoned
- 2003-12-09 AU AU2003297724A patent/AU2003297724A1/en not_active Abandoned
- 2003-12-09 AT AT03787285T patent/ATE468883T1/en not_active IP Right Cessation
- 2003-12-09 AU AU2003297723A patent/AU2003297723A1/en not_active Abandoned
- 2003-12-09 AT AT03796789T patent/ATE464932T1/en not_active IP Right Cessation
- 2003-12-09 WO PCT/US2003/038927 patent/WO2004052453A1/en not_active Application Discontinuation
- 2003-12-09 AU AU2003294595A patent/AU2003294595A1/en not_active Abandoned
- 2003-12-09 AU AU2003297735A patent/AU2003297735A1/en not_active Abandoned
- 2003-12-09 US US10/731,699 patent/US7848817B2/en active Active
- 2003-12-09 AU AU2003294596A patent/AU2003294596A1/en not_active Abandoned
- 2003-12-09 WO PCT/US2003/038940 patent/WO2004052457A1/en not_active Application Discontinuation
- 2003-12-09 US US10/730,877 patent/US8457744B2/en active Active
- 2003-12-09 AU AU2003296340A patent/AU2003296340A1/en not_active Abandoned
- 2003-12-09 US US10/731,869 patent/US20040176818A1/en not_active Abandoned
- 2003-12-09 AU AU2003297725A patent/AU2003297725A1/en not_active Abandoned
- 2003-12-09 EP EP03796789A patent/EP1578497B1/en not_active Expired - Lifetime
- 2003-12-09 US US10/731,867 patent/US7529586B2/en not_active Expired - Fee Related
- 2003-12-09 AT AT03790404T patent/ATE469670T1/en not_active IP Right Cessation
- 2003-12-09 US US10/731,881 patent/US7392089B2/en not_active Expired - Fee Related
- 2003-12-09 DE DE60332871T patent/DE60332871D1/en not_active Expired - Lifetime
- 2003-12-09 WO PCT/US2003/038926 patent/WO2004052452A1/en not_active Application Discontinuation
- 2003-12-09 WO PCT/US2003/038938 patent/WO2004052455A1/en not_active Application Discontinuation
- 2003-12-09 US US10/730,878 patent/US20040176816A1/en not_active Abandoned
- 2003-12-09 EP EP03796800A patent/EP1578499A1/en not_active Withdrawn
- 2003-12-09 WO PCT/US2003/038928 patent/WO2004052454A1/en not_active Application Discontinuation
- 2003-12-09 US US10/731,868 patent/US8397732B2/en active Active
-
2007
- 2007-04-16 US US11/735,826 patent/US20070185539A1/en not_active Abandoned
-
2010
- 2010-11-09 US US12/942,806 patent/US8666497B2/en active Active
Patent Citations (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3720874A (en) * | 1971-11-08 | 1973-03-13 | Motorola Inc | Dipole antenna arrangement for radio with separate speaker-microphone assembly |
US3888260A (en) * | 1972-06-28 | 1975-06-10 | Univ Johns Hopkins | Rechargeable demand inhibited cardiac pacer and tissue stimulator |
US4040412A (en) * | 1974-08-09 | 1977-08-09 | Sato Takuya R | Bioelectrodes |
US4010760A (en) * | 1975-05-23 | 1977-03-08 | Medtronic, Inc. | Coupling assembly for implantable electromedical devices |
US4013081A (en) * | 1976-04-19 | 1977-03-22 | Arco Medical Products Company | Pediatric cardiac pacer system |
US4256115A (en) * | 1976-12-20 | 1981-03-17 | American Technology, Inc. | Leadless cardiac pacer |
US4094321A (en) * | 1977-02-07 | 1978-06-13 | Rudolph Muto | Shallow, dome-shaped pacer with bottom storage means for catheter |
US4266552A (en) * | 1979-11-13 | 1981-05-12 | Medtronic, Inc. | Lead anchoring bobbin |
US4328813A (en) * | 1980-10-20 | 1982-05-11 | Medtronic, Inc. | Brain lead anchoring system |
US4399820A (en) * | 1981-02-26 | 1983-08-23 | Alexander Wirtzfeld | Process and device for regulating the stimulation frequency of heart pacemakers |
US4499907A (en) * | 1982-11-15 | 1985-02-19 | Medtronic, Inc. | Energy limiting cardioversion lead |
US4934368A (en) * | 1988-01-21 | 1990-06-19 | Myo/Kinetics Systems, Inc. | Multi-electrode neurological stimulation apparatus |
US4911178A (en) * | 1988-06-02 | 1990-03-27 | Neal Carol A | Pacemaker wire dressing |
US4928696A (en) * | 1989-07-26 | 1990-05-29 | Mindcenter Corporation | Electrode-supporting headset |
US5085644A (en) * | 1990-04-02 | 1992-02-04 | Pudenz-Schulte Medical Research Corporation | Sterilizable medication infusion device with dose recharge restriction |
US5116345A (en) * | 1990-11-28 | 1992-05-26 | Ohio Medical Instrument Co., Inc. | Stereotactically implanting an intracranial device |
US5312440A (en) * | 1991-03-28 | 1994-05-17 | Siemens Aktiengesellschaft | Implantable defibrillator arrangement |
US5314453A (en) * | 1991-12-06 | 1994-05-24 | Spinal Cord Society | Position sensitive power transfer antenna |
US5197332A (en) * | 1992-02-19 | 1993-03-30 | Calmed Technology, Inc. | Headset hearing tester and hearing aid programmer |
US5433734A (en) * | 1992-05-06 | 1995-07-18 | Medtronic, Inc. | Tool-less threaded connector assembly |
US5314451A (en) * | 1993-01-15 | 1994-05-24 | Medtronic, Inc. | Replaceable battery for implantable medical device |
USH1465H (en) * | 1993-09-08 | 1995-07-04 | Medtronic, Inc. | Implantable lead infection barrier |
US5489225A (en) * | 1993-12-16 | 1996-02-06 | Ventritex, Inc. | Electrical terminal with a collet grip for a defibrillator |
US6263225B1 (en) * | 1994-02-09 | 2001-07-17 | University Of Iowa Research Foundation | Stereotactic electrode assembly |
US5645586A (en) * | 1994-07-08 | 1997-07-08 | Ventritex, Inc. | Conforming implantable defibrillator |
US5896647A (en) * | 1994-09-09 | 1999-04-27 | Nec Moli Energy (Canada) Limited | Sealed electrical device with unitary fill port and terminal construction |
US5480416A (en) * | 1994-09-22 | 1996-01-02 | Intermedics, Inc. | Cardiac pacemaker with universal coating |
US5613935A (en) * | 1994-12-16 | 1997-03-25 | Jarvik; Robert | High reliability cardiac assist system |
US5638832A (en) * | 1995-06-07 | 1997-06-17 | Interval Research Corporation | Programmable subcutaneous visible implant |
US5873899A (en) * | 1996-01-16 | 1999-02-23 | Pacesetter Inc. | Implantable medical device having compliant support for internal components |
US6214032B1 (en) * | 1996-02-20 | 2001-04-10 | Advanced Bionics Corporation | System for implanting a microstimulator |
US5769874A (en) * | 1996-03-26 | 1998-06-23 | Pacesetter Ab | Active medical implant with a hermetically sealed capsule |
US5755743A (en) * | 1996-06-05 | 1998-05-26 | Implex Gmbh Spezialhorgerate | Implantable unit |
US5741313A (en) * | 1996-09-09 | 1998-04-21 | Pacesetter, Inc. | Implantable medical device with a reduced volumetric configuration and improved shock stabilization |
US5876424A (en) * | 1997-01-23 | 1999-03-02 | Cardiac Pacemakers, Inc. | Ultra-thin hermetic enclosure for implantable medical devices |
US5935154A (en) * | 1997-01-24 | 1999-08-10 | Cardiac Pacemakers, Inc. | Implantable tissue stimulator incorporating deposited multilayer capacitor |
US5776169A (en) * | 1997-04-28 | 1998-07-07 | Sulzer Intermedics Inc. | Implantable cardiac stimulator for minimally invasive implantation |
US6067474A (en) * | 1997-08-01 | 2000-05-23 | Advanced Bionics Corporation | Implantable device with improved battery recharging and powering configuration |
US5919215A (en) * | 1997-08-01 | 1999-07-06 | Medtronic, Inc. | Attachment apparatus for an implantable medical device employing ultrasonic energy |
US6205358B1 (en) * | 1997-08-01 | 2001-03-20 | Medtronic, Inc. | Method of making ultrasonically welded, staked of swaged components in an implantable medical device |
US6248080B1 (en) * | 1997-09-03 | 2001-06-19 | Medtronic, Inc. | Intracranial monitoring and therapy delivery control device, system and method |
US5941905A (en) * | 1997-09-29 | 1999-08-24 | Cochlear Limited | Public alarm for cochlear implant |
US5941906A (en) * | 1997-10-15 | 1999-08-24 | Medtronic, Inc. | Implantable, modular tissue stimulator |
US6061593A (en) * | 1997-10-27 | 2000-05-09 | Neuropace, Inc. | EEG d-c voltage shift as a means for detecting the onset of a neurological event |
US20020002390A1 (en) * | 1997-10-27 | 2002-01-03 | Fischell Robert E. | Implantable neurostimulator having a data communication link |
US6597954B1 (en) * | 1997-10-27 | 2003-07-22 | Neuropace, Inc. | System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes |
US6360122B1 (en) * | 1997-10-27 | 2002-03-19 | Neuropace, Inc. | Data recording methods for an implantable device |
US6016449A (en) * | 1997-10-27 | 2000-01-18 | Neuropace, Inc. | System for treatment of neurological disorders |
US20020099412A1 (en) * | 1997-10-27 | 2002-07-25 | Neuropace, Inc. | Methods for using an implantable device for patient communication |
US6354299B1 (en) * | 1997-10-27 | 2002-03-12 | Neuropace, Inc. | Implantable device for patient communication |
US6427086B1 (en) * | 1997-10-27 | 2002-07-30 | Neuropace, Inc. | Means and method for the intracranial placement of a neurostimulator |
US6016593A (en) * | 1998-04-10 | 2000-01-25 | Kyrstein Investments Ltd. | Electric drive system for planer mill infeed and outfeed rolls |
US6266556B1 (en) * | 1998-04-27 | 2001-07-24 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation |
US6044304A (en) * | 1998-04-29 | 2000-03-28 | Medtronic, Inc. | Burr ring with integral lead/catheter fixation device |
US6176879B1 (en) * | 1998-07-02 | 2001-01-23 | Implex Aktienegesellschaft Hearing Technology | Medical implant |
US6091979A (en) * | 1998-07-07 | 2000-07-18 | Children's Medical Center Corporation | Subdural electrode arrays for monitoring cortical electrical activity |
US6366813B1 (en) * | 1998-08-05 | 2002-04-02 | Dilorenzo Daniel J. | Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease |
US6218016B1 (en) * | 1998-09-29 | 2001-04-17 | Medtronic Ave, Inc. | Lubricious, drug-accommodating coating |
US20060129205A1 (en) * | 1998-10-26 | 2006-06-15 | Boveja Birinder R | Method and system for cortical stimulation with rectangular and/or complex electrical pulses to provide therapy for stroke and other neurological disorders |
US6168580B1 (en) * | 1999-03-26 | 2001-01-02 | Iontophoretics Corporation | Antimicrobial device and methods for long-term catheters |
US6259951B1 (en) * | 1999-05-14 | 2001-07-10 | Advanced Bionics Corporation | Implantable cochlear stimulator system incorporating combination electrode/transducer |
US6516227B1 (en) * | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
US6230049B1 (en) * | 1999-08-13 | 2001-05-08 | Neuro Pace, Inc. | Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes |
US6560486B1 (en) * | 1999-10-12 | 2003-05-06 | Ivan Osorio | Bi-directional cerebral interface system |
US6882881B1 (en) * | 1999-10-19 | 2005-04-19 | The Johns Hopkins University | Techniques using heat flow management, stimulation, and signal analysis to treat medical disorders |
US6358281B1 (en) * | 1999-11-29 | 2002-03-19 | Epic Biosonics Inc. | Totally implantable cochlear prosthesis |
US20020019669A1 (en) * | 1999-11-29 | 2002-02-14 | Epic Biosonics Inc. | Totally implantable cochlear prosthesis |
US6356792B1 (en) * | 2000-01-20 | 2002-03-12 | Electro Core Technologies, Llc | Skull mounted electrode lead securing assembly |
US6537200B2 (en) * | 2000-03-28 | 2003-03-25 | Cochlear Limited | Partially or fully implantable hearing system |
US20030073972A1 (en) * | 2000-04-05 | 2003-04-17 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
US6565503B2 (en) * | 2000-04-13 | 2003-05-20 | Cochlear Limited | At least partially implantable system for rehabilitation of hearing disorder |
US6575894B2 (en) * | 2000-04-13 | 2003-06-10 | Cochlear Limited | At least partially implantable system for rehabilitation of a hearing disorder |
US6517476B1 (en) * | 2000-05-30 | 2003-02-11 | Otologics Llc | Connector for implantable hearing aid |
US20020013612A1 (en) * | 2000-06-20 | 2002-01-31 | Whitehurst Todd K. | System and method for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion |
US7010351B2 (en) * | 2000-07-13 | 2006-03-07 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US20020087201A1 (en) * | 2000-07-13 | 2002-07-04 | Firlik Andrew D. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US20030125786A1 (en) * | 2000-07-13 | 2003-07-03 | Gliner Bradford Evan | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US20030130706A1 (en) * | 2000-07-13 | 2003-07-10 | Sheffield W. Douglas | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US6554762B2 (en) * | 2000-08-25 | 2003-04-29 | Cochlear Limited | Implantable hearing system with means for measuring its coupling quality |
US20020051550A1 (en) * | 2000-08-25 | 2002-05-02 | Hans Leysieffer | Implantable hermetically sealed housing for an implantable medical device and process for producing the same |
US20030004546A1 (en) * | 2000-08-29 | 2003-01-02 | Casey Don E. | Subcutaneously implantable power supply |
US20020042634A1 (en) * | 2000-09-18 | 2002-04-11 | Cameron Health, Inc. | Ceramics and/or other material insulated shell for active and non-active S-ICD can |
US20020068958A1 (en) * | 2000-09-18 | 2002-06-06 | Cameron Health, Inc. | Radian curve shaped implantable cardioverter-defibrillator canister |
US6405079B1 (en) * | 2000-09-22 | 2002-06-11 | Mehdi M. Ansarinia | Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions |
US6899976B2 (en) * | 2000-10-13 | 2005-05-31 | Medtronic Inc | Feed through assembly for a formable flat battery |
US6567703B1 (en) * | 2000-11-08 | 2003-05-20 | Medtronic, Inc. | Implantable medical device incorporating miniaturized circuit module |
US6726678B1 (en) * | 2001-02-22 | 2004-04-27 | Isurgical, Llc | Implantable reservoir and system for delivery of a therapeutic agent |
US20030004428A1 (en) * | 2001-06-28 | 2003-01-02 | Pless Benjamin D. | Seizure sensing and detection using an implantable device |
US20030085684A1 (en) * | 2001-11-07 | 2003-05-08 | Quallion Llc | Implantable medical power module |
US20030109903A1 (en) * | 2001-12-12 | 2003-06-12 | Epic Biosonics Inc. | Low profile subcutaneous enclosure |
US20030120320A1 (en) * | 2001-12-20 | 2003-06-26 | Medtronic,Inc. | Implantable medical device having a housing or component case with an insulating material formed thereon, and methods of making same |
US20060116743A1 (en) * | 2002-08-09 | 2006-06-01 | Peter Gibson | Fixation system for an implantable medical device |
US20050075679A1 (en) * | 2002-09-30 | 2005-04-07 | Gliner Bradford E. | Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system |
US20040082977A1 (en) * | 2002-10-25 | 2004-04-29 | Engmark David B. | Implantable medical device with air core antenna assembly |
US20040102828A1 (en) * | 2002-11-27 | 2004-05-27 | Lowry David Warren | Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography |
US20050033378A1 (en) * | 2002-12-09 | 2005-02-10 | Sheffield Warren Douglas | Methods for treating and/or collecting information regarding neurological disorders, including language disorders |
US7212864B2 (en) * | 2002-12-09 | 2007-05-01 | Medtronic, Inc. | Modular implantable medical device |
US7242982B2 (en) * | 2002-12-09 | 2007-07-10 | Medtronic, Inc. | Overmold for a modular implantable medical device |
US20050070971A1 (en) * | 2003-08-01 | 2005-03-31 | Brad Fowler | Apparatus and methods for applying neural stimulation to a patient |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7758568B2 (en) | 2001-04-10 | 2010-07-20 | Medtronic, Inc. | Implantable therapeutic substance delivery device |
US20040220553A1 (en) * | 2001-04-10 | 2004-11-04 | Medtronic, Inc. | Implantable therapeutic substance delivery device |
US20020173773A1 (en) * | 2001-04-10 | 2002-11-21 | Olsen James M. | Permanent magnet solenoid pump for an implantable therapeutic substance delivery device |
US7288085B2 (en) | 2001-04-10 | 2007-10-30 | Medtronic, Inc. | Permanent magnet solenoid pump for an implantable therapeutic substance delivery device |
US8666497B2 (en) | 2002-12-09 | 2014-03-04 | Medtronic, Inc. | Coupling module of a modular implantable medical device |
US8086313B2 (en) | 2002-12-09 | 2011-12-27 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
US7881796B2 (en) | 2003-05-16 | 2011-02-01 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
US8725262B2 (en) | 2003-10-02 | 2014-05-13 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US9463324B2 (en) | 2003-10-02 | 2016-10-11 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US20100076524A1 (en) * | 2003-10-02 | 2010-03-25 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US8005547B2 (en) | 2003-10-02 | 2011-08-23 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US11318250B2 (en) | 2003-10-02 | 2022-05-03 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US8165678B2 (en) | 2003-10-02 | 2012-04-24 | Medtronic, Inc. | Inductively rechargeable external energy source, charger and system for a transcutaneous inductive charger for an implantable medical device |
US10369275B2 (en) | 2003-10-02 | 2019-08-06 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US8554322B2 (en) | 2003-10-02 | 2013-10-08 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US7225032B2 (en) | 2003-10-02 | 2007-05-29 | Medtronic Inc. | External power source, charger and system for an implantable medical device having thermal characteristics and method therefore |
US20050075694A1 (en) * | 2003-10-02 | 2005-04-07 | Medtronic, Inc. | External power source, charger and system for an implantable medical device having thermal characteristics and method therefore |
US9821112B2 (en) | 2003-10-02 | 2017-11-21 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US20110022125A1 (en) * | 2003-10-02 | 2011-01-27 | Medtronic, Inc. | Inductively rechargeable external energy source, charger, system and method for a transcutaneous inductive charger for an implantable medical device |
US8280478B2 (en) | 2004-04-29 | 2012-10-02 | Medtronic, Inc. | Evaluation of implantation site for implantation of implantable medical device |
US9084901B2 (en) | 2006-04-28 | 2015-07-21 | Medtronic, Inc. | Cranial implant |
US9504402B2 (en) | 2006-04-28 | 2016-11-29 | Medtronic, Inc. | Cranial implant |
WO2008113091A1 (en) * | 2007-03-21 | 2008-09-25 | Med-El Elektromedizinische Geräte Gesellschaft M.B.H. | System for electrically stimulating muscles or nerves |
US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
US20140277217A1 (en) * | 2013-03-15 | 2014-09-18 | Medtronic, Inc. | Implantable device with internal lead connector |
US10071253B2 (en) * | 2013-03-15 | 2018-09-11 | Medtronic, Inc. | Implantable device with internal lead connector |
US11058541B2 (en) | 2015-09-04 | 2021-07-13 | The Johns Hopkins University | Low-profile intercranial device |
US10912648B2 (en) | 2016-08-30 | 2021-02-09 | Longeviti Neuro Solutions Llc | Method for manufacturing a low-profile intercranial device and the low-profile intercranial device manufactured thereby |
US11446148B2 (en) | 2016-08-30 | 2022-09-20 | Longeviti Neuro Solutions Llc | Method for manufacturing a low-profile intercranial device and the low-profile intercranial device manufactured thereby |
US11589992B2 (en) | 2018-01-09 | 2023-02-28 | Longeviti Neuro Solutions Llc | Universal low-profile intercranial assembly |
WO2020205843A1 (en) * | 2019-04-01 | 2020-10-08 | Boston Scientific Neuromodulation Corporation | Systems and methods for making and using a low-profile control module for an electrical stimulation system |
US11357992B2 (en) | 2019-05-03 | 2022-06-14 | Boston Scientific Neuromodulation Corporation | Connector assembly for an electrical stimulation system and methods of making and using |
US11612755B2 (en) | 2019-05-03 | 2023-03-28 | Boston Scientific Neuromodulation Corporation | Connector assembly for an electrical stimulation system and methods of making and using |
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