US20040210291A1 - Spinal cord stimulation lead with an anode guard - Google Patents
Spinal cord stimulation lead with an anode guard Download PDFInfo
- Publication number
- US20040210291A1 US20040210291A1 US10/844,672 US84467204A US2004210291A1 US 20040210291 A1 US20040210291 A1 US 20040210291A1 US 84467204 A US84467204 A US 84467204A US 2004210291 A1 US2004210291 A1 US 2004210291A1
- Authority
- US
- United States
- Prior art keywords
- electrode
- stimulation lead
- electrodes
- terminals
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0553—Paddle shaped electrodes, e.g. for laminotomy
Definitions
- the present invention relates to an epidural stimulation lead, and in particular, to an epidural stimulation lead having at least one electrode suited to serve as an anode guard relative to a substantially encircled cathode.
- each exterior region, or each dermatome, of the human body is associated with a particular spinal nerve root at a particular longitudinal spinal position.
- the head and neck regions are associated with C2-C8, the back regions extends from C2-S3, the central diaphragm is associated with spinal nerve roots between C3 and C5, the upper extremities are correspond to C5 and T1, the thoracic wall extends from T1 to T11, the peripheral diaphragm is between T6 and T11, the abdominal wall is associated with T6-L1, lower extremities are located from L2 to S2, and the perineum from L4 to S4.
- a specific energy field can usually be applied to a region between bony level T8 and T10.
- successful pain management and the avoidance of stimulation in unafflicted regions necessarily requires the applied electric field to be properly positioned longitudinally along the dorsal column.
- Nerve fibers extend between the brain and a nerve root along the same side of the dorsal column as the peripheral areas the fibers represent. Pain that is concentrated on only one side of the body is “unilateral” in nature. To address unilateral pain, electrical energy is applied to neural structures on the side of a dorsal column that directly corresponds to a side of the body subject to pain. Pain that is present on both sides of a patient is “bilateral.” Accordingly, bilateral pain is addressed through either an application of electrical energy along a patient's physiological midline or an application of electrical energy that transverses the physiological midline.
- Pain-managing electrical energy is commonly delivered through electrodes positioned external to the dura layer surrounding the spinal cord.
- the electrodes are carried by two primary vehicles: a percutaneous catheter and a laminotomy lead.
- Percutaneous catheters or percutaneous leads, commonly have three or more, equally-spaced electrodes, which are placed above the dura layer through the use of a Touhy-like needle.
- the Touhy-like needle is passed through the skin, between desired vertebrae, to open above the dura layer.
- percutaneous leads are positioned on a side of a dorsal column corresponding to the “afflicted” side of the body, as discussed above, and for bilateral pain, a single percutaneous lead is positioned along the patient midline (or two or more leads are positioned on each side of the midline).
- Laminotomy leads have a paddle configuration and typically possess a plurality of electrodes (for example, two, four, eight, or sixteen) arranged in one or more columns.
- a sixteen-electrode laminotomy lead is shown in FIG. 1.
- Implanted laminotomy leads are commonly transversely centered over the physiological midline of a patient. In such position, multiple columns of electrodes are well suited to address both unilateral and bilateral pain, where electrical energy may be administered using either column independently (on either side of the midline) or administered using both columns to create an electric field which traverses the midline.
- a multi-column laminotomy lead enables reliable positioning of a plurality of electrodes, and in particular, a plurality of electrode columns that do not readily deviate from an initial implantation position.
- Laminotomy leads require a surgical procedure for implantation.
- the surgical procedure, or partial laminectomy requires the resection and removal of certain vertebral tissue to allow both access to the dura and proper positioning of a laminotomy lead.
- the laminotomy lead offers a more stable platform, which is further capable of being sutured in place, that tends to migrate less in the operating environment of the human body.
- Percutaneous leads require a less-invasive implantation method and, with a plurality of leads, provide a user the ability to create almost any electrode array. Although likely more stable during use, laminotomy leads do not offer an opportunity for electrode array variance due to the predetermined structure which defines their electrode arrays.
- stimulation leads are connected to multi-programmable stimulation systems, or energy sources (not shown).
- energy sources not shown
- each electrode of a connected stimulation lead to be set as an anode (+), a cathode ( ⁇ ), or in an OFF-state.
- an electric current “flows” from an anode to a cathode. Consequently, using the laminotomy lead of FIG. 1 as an example, a range of very simple to very complex electric fields can be created by defining different electrodes in various combinations of (+), ( ⁇ ), and OFF.
- a functional combination must include at least one anode and at least one cathode.
- At least one aspect of the present invention is drawn to a stimulation lead having a plurality of terminals, a plurality of electrodes carried by a body, and a plurality of conductors, as a conductor electrically couples one terminal with a respective electrode.
- the plurality of electrodes includes a first electrode and a second electrode, whereby the second electrode substantially encircles at least the first electrode.
- An object of the present invention is to provide a electrical stimulation lead having at least two electrodes. Unlike known stimulation leads, however, an arrangement of the electrodes of the stimulation lead should facilitate operatively concentrating delivered electrical energy at a point, i.e., for a given electrode, or over a small region, i.e., for a plurality of electrodes.
- FIG. 1 is a plan view of a conventional laminotomy spinal cord stimulation lead
- FIG. 2 is a plan view of a laminotomy spinal cord stimulation lead that illustrates the fundamental principle of construction of the present invention
- FIG. 3 is a plan view of a first embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention
- FIG. 4 is a plan view of a second embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention.
- FIG. 5 is a plan view of a third embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention.
- FIG. 6 illustrates a percutaneous implantation of the laminotomy spinal cord stimulation lead of FIG. 3.
- the illustrated laminotomy lead 10 includes a proximal end 12 and a distal end 14 .
- the proximal end 12 includes a plurality of electrically conductive terminals 18
- the distal end 14 includes a plurality of electrically conductive electrodes 20 arranged within a flat, thin paddle-like structure 16 .
- each terminal 18 is electrically connected to a single electrode 20 via a conductor 22 ; however, a terminal 18 can be connected to two or more electrodes 20 .
- Terminals 18 and electrodes 20 are preferably formed of a non-corrosive, highly conductive material. Examples of such material include stainless steel, MP35N, platinum, and platinum alloys. In a preferred embodiment, terminals 18 and electrodes 20 are formed of a platinum-iridium alloy.
- the sheaths 24 and the paddle structure 16 are formed from a medical grade, substantially inert material, for example, polyurethane, silicone, or the like. Importantly, such material must be non-reactive to the environment of the human body, provide a flexible and durable (i.e., fatigue resistant) exterior structure for the components of lead 10 , and insulate adjacent terminals 18 and/or electrodes 20 . Additional structure (e.g., a nylon mesh, a fiberglass substrate) (not shown) can be internalized within the paddle structure 16 to increase its overall rigidity and/or to cause the paddle structure 16 to assume a prescribed cross-sectional form (e.g., a prescribed arc along a transverse direction of the paddle structure 16 ) (not shown).
- a prescribed cross-sectional form e.g., a prescribed arc along a transverse direction of the paddle structure 16
- each sheath 24 carries eight (8) conductors 22 .
- the cross-sectional area of each conductor 20 is restricted.
- each conductor 22 would be approximately 0.0065 inches in diameter.
- Each conductor 22 is formed of a conductive material that exhibits desired mechanical properties of low resistance, corrosion resistance, flexibility, and strength. While conventional stranded bundles of stainless steel, MP35N , platinum, platinum-iridium alloy, drawn-brazed silver (DBS) or the like can be used, a preferred embodiment of the present invention uses conductors 22 formed of multi-strands of drawn-filled tubes (DFT). Each strand is formed of a low resistance material and is encased in a high strength material (preferably, metal). A selected number of “sub-strands” are wound and coated with an insulative material.
- DFT drawn-filled tubes
- such insulative material protects the individual conductors 22 if its respective sheath 24 was breached during use.
- Wire formed of multi-strands of drawn-filled tubes to form conductors 22 is available from Temp-Flex Cable, Inc. (City, State).
- conductors 22 formed of multi-strands of drawn-filled tubes provide a low resistance alternative to other conventional materials. Specifically, a stranded wire, or even a coiled wire, of approximately 60 cm and formed of MP35N or stainless steel or the like would have a measured resistance in excess of 30 ohms. In contrast, for the same length, a wire formed of multi-strands of drawn-filled tubes could have a resistance less than 4 ohms. Accordingly, in a preferred embodiment, each conductor 22 , having a length equal to or less than 60 cm, has a resistance of less than 25 ohms.
- each conductor 20 having a length equal to or less than 60 cm, has a resistance equal to or less than 10 ohms. In a most preferred embodiment, each conductor 20 , having a length equal to or less than 60 cm, has a resistance of less than 4 ohms.
- the present invention is characterized by a first electrode, or a first electrode array, that substantially encompasses or circumscribes at least one independently controlled electrode.
- the first electrode or first electrode array
- the first electrode can operatively form an “anode guard” relative to the substantially surrounded independently controlled electrode(s).
- FIG. 2 illustrates a laminotomy lead 100 a featuring the fundamental principle of construction of the present invention.
- the paddle structure 16 includes a plurality of electrodes 20 , wherein one electrode 30 substantially surrounds another electrode 40 .
- each electrode is electrically coupled to an independent terminal (not shown), which is connectable to a programmable energy source, for example, a pulse generator (not shown).
- a programmable energy source for example, a pulse generator (not shown).
- the construction and arrangement of the terminals (and related conductors, which establish the desired electrical coupling) are not in themselves unique but are consistent with that described hereinabove.
- either the electrode 30 or the electrode 40 could operatively assume a positive polarity (with the remaining electrode assuming a negative polarity) during active delivery of electrical energy therefrom.
- the electrode 30 assumes a positive polarity, whereby in such a condition the electrode 30 forms an “anode guard” relative to the encompassed electrode 40 .
- the electrode 30 can be constructed in a manner and from a material consistent with that used to form electrode 40 .
- the electrode(s) 30 be formed so as to not otherwise significantly impair the inherent flexibility of the paddle structure 16 . Accordingly, the electrode 30 can be constructed using less material—in a thickness direction—than an electrode 40 , formed from a conductive film/foil applied to the surface of the paddle structure 16 , formed through deposition of a conductive material, constructed using a coil (FIG. 3), or formed using other like processes/techniques that are well known in the art.
- An anode guard functions, in part, to laterally limit an applied electrical field, which assists in reducing extraneous stimulation of surrounding neural tissue.
- neural tissue at or immediately about the cathode electrode(s) is depolarized, while neural tissue relative to the anode guard is subject to hyperpolarization.
- an anode guard in accordance with that illustrated in FIG. 2 focuses an applied electrical field from practically every direction to any cathode-electrode(s) positioned therein.
- the stimulation lead of the present invention can effect a deeper application of applied energy than stimulation leads of a conventional nature.
- FIG. 3 illustrates a four-channel (a “channel” represents a controllable electrical output) laminotomy stimulation lead 100 b in accordance with the present invention.
- the stimulation lead 100 b is shown having a plurality of electrodes 20 , which includes an electrode 30 , formed from a coil, that substantially circumscribes an electrode array formed of three electrodes 40 a, 40 b, and 40 c.
- each of the plurality of electrodes 20 could individually function as a cathode or an anode, or placed in an OFF-state, it is intended that the electrode 30 , as an anode guard, assume a positive polarity.
- the form of an electric field generated using the electrode 30 is altered/controlled through setting each of the electrodes 40 a, 40 b, and 40 c as a cathode, an anode, or in an OFF-state.
- Such control over the electrodes 40 a, 40 b, and 40 c enables formation of a focused electrical field with a single electrode 40 as a cathode or a more diverse electrical field spread over two or more electrodes 40 , whereas each electrode 40 of such plurality functions as a cathode.
- the electrode 30 may be placed in an OFF-state.
- the laminotomy lead 100 b then functions in a manner consistent with conventional laminotomy stimulation leads.
- the configuration illustrated in at least FIG. 3 enables the delivery of electrical energy to targeted nervous tissue with fewer required electrodes.
- the narrow transverse dimension of the laminotomy lead 100 b enables such laminotomy lead to be implanted percutaneously, if so desired, using a special insertion needle 200 that accommodates the greater dimensions of a laminotomy lead, for example, the laminotomy lead 100 b.
- implantation of the present invention would be similar that described hereinabove in the context of percutaneous catheters.
- FIG. 4 illustrates a laminotomy stimulation lead 100 c in accordance with the present invention.
- the stimulation lead 100 c includes a plurality of electrodes 20 , which includes a first electrode array having a plurality of electrodes 30 a - 30 d that substantially surrounds a second electrode array having a plurality of electrodes 40 .
- the second electrode array of the stimulation lead 100 c is formed of a group of individual electrodes that can respectively be set as an anode, a cathode, or in an OFF-state.
- the electrodes 40 of the stimulation lead 100 c are shown in two, staggered columns, the arrangement of the electrodes 40 of the second electrode array is not critical to the present invention—the electrodes 40 of the second electrode array may assume any multiple-column arrangement.
- the anode guard is constructed of a first electrode array that includes electrodes 30 a - 30 d.
- each electrode of the first electrode array extends for a length substantially equivalent to a comparable dimension of at least two of electrodes 40 of the second electrode array.
- the collection of electrodes 30 a - 30 d form an effectively continuous ring that substantially extends about the second electrode array.
- each of the electrodes 30 a - 30 d may be electrically independent (i.e., coupled to respective conductors/terminals), allowing each respective electrode to be an anode, a cathode, or set to an OFF-state, in consideration of practical space limitations, it may be advisable to electrically couple two or more of electrodes 30 a - 30 d.
- electrodes 30 a - 30 d are electrically linked so as to maintain the same electrical state during operation and minimize the number of conductors necessary to couple the first electrode array to an energy source.
- the segmented nature of the illustrated first electrode array of this embodiment would improve longitudinal flexibility of the paddle structure 16 .
- additional segmentation of electrodes 30 b and 30 d would likewise improve transverse flexibility of the paddle structure 16 , such modification is within the scope of this embodiment of the present invention.
- the distance between the one or more cathode-electrodes and the anode guard should be largely equidistant. Achieving this optimum arrangement is typically hindered by both a need that the platform structure 16 fit easily within the narrow confines of the human epidural space and a desire that the provided electrode array(s) span a significant vertebral range of spinal nervous tissue.
- the electrodes 40 can be divided into groups 40 a and 40 b, and each electrode group 40 a and 40 b is encompassed by its own independently controlled anode guard electrode 30 a and 30 b.
Abstract
The present invention relates to an epidural stimulation lead having at least one electrode that substantially encircles another electrode. Operatively, the encircling electrode can be set as an anode and the encircled electrode can be set as a cathode to generate an electrical field therebetween. The encircling electrode functions in this capacity as an anode guard, which among other things, concentrates the electrical field about the designated cathode and limits the lateral range of a generated electrical field.
Description
- The present invention relates to an epidural stimulation lead, and in particular, to an epidural stimulation lead having at least one electrode suited to serve as an anode guard relative to a substantially encircled cathode.
- Application of specific electrical fields to spinal nerve roots, spinal cord, and other nerve bundles for the purpose of chronic pain control has been actively practiced since the 1960s. While a precise understanding of the interaction between the applied electrical energy and the nervous tissue is not fully appreciated, it is known that application of an electrical field to spinal nervous tissue (i.e., spinal nerve roots and spinal-cord bundles) can effectively mask certain types of pain transmitted from regions of the body associated with the stimulated tissue. More specifically, applying particularized electrical energy to the spinal cord associated with regions of the body afflicted with chronic pain can induce paresthesia, or a subjective sensation of numbness or tingling, in the afflicted bodily regions. This paresthesia can effectively mask the transmission of non-acute pain sensations to the brain.
- It is known that each exterior region, or each dermatome, of the human body is associated with a particular spinal nerve root at a particular longitudinal spinal position. The head and neck regions are associated with C2-C8, the back regions extends from C2-S3, the central diaphragm is associated with spinal nerve roots between C3 and C5, the upper extremities are correspond to C5 and T1, the thoracic wall extends from T1 to T11, the peripheral diaphragm is between T6 and T11, the abdominal wall is associated with T6-L1, lower extremities are located from L2 to S2, and the perineum from L4 to S4. By example, to address chronic pain sensations that commonly focus on the lower back and lower extremities, a specific energy field can usually be applied to a region between bony level T8 and T10. As should be understood, successful pain management and the avoidance of stimulation in unafflicted regions necessarily requires the applied electric field to be properly positioned longitudinally along the dorsal column.
- Positioning of an applied electrical field relative to a physiological midline is equally important. Nerve fibers extend between the brain and a nerve root along the same side of the dorsal column as the peripheral areas the fibers represent. Pain that is concentrated on only one side of the body is “unilateral” in nature. To address unilateral pain, electrical energy is applied to neural structures on the side of a dorsal column that directly corresponds to a side of the body subject to pain. Pain that is present on both sides of a patient is “bilateral.” Accordingly, bilateral pain is addressed through either an application of electrical energy along a patient's physiological midline or an application of electrical energy that transverses the physiological midline.
- Pain-managing electrical energy is commonly delivered through electrodes positioned external to the dura layer surrounding the spinal cord. The electrodes are carried by two primary vehicles: a percutaneous catheter and a laminotomy lead.
- Percutaneous catheters, or percutaneous leads, commonly have three or more, equally-spaced electrodes, which are placed above the dura layer through the use of a Touhy-like needle. For insertion, the Touhy-like needle is passed through the skin, between desired vertebrae, to open above the dura layer.
- For unilateral pain, percutaneous leads are positioned on a side of a dorsal column corresponding to the “afflicted” side of the body, as discussed above, and for bilateral pain, a single percutaneous lead is positioned along the patient midline (or two or more leads are positioned on each side of the midline).
- Laminotomy leads have a paddle configuration and typically possess a plurality of electrodes (for example, two, four, eight, or sixteen) arranged in one or more columns. An example of a sixteen-electrode laminotomy lead is shown in FIG. 1.
- Implanted laminotomy leads are commonly transversely centered over the physiological midline of a patient. In such position, multiple columns of electrodes are well suited to address both unilateral and bilateral pain, where electrical energy may be administered using either column independently (on either side of the midline) or administered using both columns to create an electric field which traverses the midline. A multi-column laminotomy lead enables reliable positioning of a plurality of electrodes, and in particular, a plurality of electrode columns that do not readily deviate from an initial implantation position.
- Laminotomy leads require a surgical procedure for implantation. The surgical procedure, or partial laminectomy, requires the resection and removal of certain vertebral tissue to allow both access to the dura and proper positioning of a laminotomy lead. The laminotomy lead offers a more stable platform, which is further capable of being sutured in place, that tends to migrate less in the operating environment of the human body.
- Percutaneous leads require a less-invasive implantation method and, with a plurality of leads, provide a user the ability to create almost any electrode array. Although likely more stable during use, laminotomy leads do not offer an opportunity for electrode array variance due to the predetermined structure which defines their electrode arrays.
- To supply suitable pain-managing electrical energy, stimulation leads are connected to multi-programmable stimulation systems, or energy sources (not shown). Typically, such systems enable each electrode of a connected stimulation lead to be set as an anode (+), a cathode (−), or in an OFF-state. As is well known, an electric current “flows” from an anode to a cathode. Consequently, using the laminotomy lead of FIG. 1 as an example, a range of very simple to very complex electric fields can be created by defining different electrodes in various combinations of (+), (−), and OFF. Of course, in any instance, a functional combination must include at least one anode and at least one cathode.
- Notwithstanding the range of electric fields that are possible with conventional stimulation leads, in certain instances it is necessary to concentrate electrical energy at a particular point, or over a small region. As an example of such occasion, assume pain-managing electrical energy is applied at or about T8 to address only localized lower back pain. At T8, however, spinal nervous tissue corresponding to the patient's lower extremities commingles with the specific spinal nervous tissue associated with the lower back. Moreover, it is common that the lower back-related spinal nervous tissue is deeply embedded within the combined spinal nervous tissue. Accordingly, it becomes desirable to focus applied electrical energy to the targeted nervous tissue to (i) reach the deeply situated target nervous tissue and (ii) avoid undesirable stimulation of unafflicted regions.
- Accordingly, a need exists for a stimulation lead that includes a structural arrangement that facilitates a concentration of delivered electrical energy at a point, i.e., for a given electrode, or over a small region, i.e., for a plurality of electrodes.
- At least one aspect of the present invention is drawn to a stimulation lead having a plurality of terminals, a plurality of electrodes carried by a body, and a plurality of conductors, as a conductor electrically couples one terminal with a respective electrode. The plurality of electrodes includes a first electrode and a second electrode, whereby the second electrode substantially encircles at least the first electrode.
- An object of the present invention is to provide a electrical stimulation lead having at least two electrodes. Unlike known stimulation leads, however, an arrangement of the electrodes of the stimulation lead should facilitate operatively concentrating delivered electrical energy at a point, i.e., for a given electrode, or over a small region, i.e., for a plurality of electrodes.
- Other objects and advantages of the present invention will be apparent to those of ordinary skill in the art having reference to the following specification together with the drawings.
- FIG. 1 is a plan view of a conventional laminotomy spinal cord stimulation lead;
- FIG. 2 is a plan view of a laminotomy spinal cord stimulation lead that illustrates the fundamental principle of construction of the present invention;
- FIG. 3 is a plan view of a first embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention;
- FIG. 4 is a plan view of a second embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention;
- FIG. 5 is a plan view of a third embodiment of a laminotomy spinal cord stimulation lead in accordance with the present invention; and
- FIG. 6 illustrates a percutaneous implantation of the laminotomy spinal cord stimulation lead of FIG. 3.
- Various embodiments, including preferred embodiments, will now be described in detail below with reference to the drawings.
- In reference to FIG. 1, the illustrated
laminotomy lead 10 includes aproximal end 12 and adistal end 14. Theproximal end 12 includes a plurality of electricallyconductive terminals 18, and thedistal end 14 includes a plurality of electricallyconductive electrodes 20 arranged within a flat, thin paddle-like structure 16. Typically, eachterminal 18 is electrically connected to asingle electrode 20 via aconductor 22; however, aterminal 18 can be connected to two ormore electrodes 20. -
Terminals 18 andelectrodes 20 are preferably formed of a non-corrosive, highly conductive material. Examples of such material include stainless steel, MP35N, platinum, and platinum alloys. In a preferred embodiment,terminals 18 andelectrodes 20 are formed of a platinum-iridium alloy. - The
sheaths 24 and thepaddle structure 16 are formed from a medical grade, substantially inert material, for example, polyurethane, silicone, or the like. Importantly, such material must be non-reactive to the environment of the human body, provide a flexible and durable (i.e., fatigue resistant) exterior structure for the components oflead 10, and insulateadjacent terminals 18 and/orelectrodes 20. Additional structure (e.g., a nylon mesh, a fiberglass substrate) (not shown) can be internalized within thepaddle structure 16 to increase its overall rigidity and/or to cause thepaddle structure 16 to assume a prescribed cross-sectional form (e.g., a prescribed arc along a transverse direction of the paddle structure 16) (not shown). - The
conductors 22 are carried insheaths 24. In the illustrated example, eachsheath 24 carries eight (8)conductors 22. Given the number ofconductors 22 that are typically carried within eachsheath 24, the cross-sectional area of eachconductor 20 is restricted. As but one example, for asheath 24 in accordance with the present invention, having an outer diameter of approximately 0.055 inches, eachconductor 22 would be approximately 0.0065 inches in diameter. - Each
conductor 22 is formed of a conductive material that exhibits desired mechanical properties of low resistance, corrosion resistance, flexibility, and strength. While conventional stranded bundles of stainless steel, MP35N , platinum, platinum-iridium alloy, drawn-brazed silver (DBS) or the like can be used, a preferred embodiment of the present invention usesconductors 22 formed of multi-strands of drawn-filled tubes (DFT). Each strand is formed of a low resistance material and is encased in a high strength material (preferably, metal). A selected number of “sub-strands” are wound and coated with an insulative material. With regard to the operating environment of the present invention, such insulative material protects theindividual conductors 22 if itsrespective sheath 24 was breached during use. Wire formed of multi-strands of drawn-filled tubes to formconductors 22, as discussed here, is available from Temp-Flex Cable, Inc. (City, State). - In addition to providing the requisite strength, flexibility, and resistance to fatigue,
conductors 22 formed of multi-strands of drawn-filled tubes, in accordance with the above description, provide a low resistance alternative to other conventional materials. Specifically, a stranded wire, or even a coiled wire, of approximately 60 cm and formed of MP35N or stainless steel or the like would have a measured resistance in excess of 30 ohms. In contrast, for the same length, a wire formed of multi-strands of drawn-filled tubes could have a resistance less than 4 ohms. Accordingly, in a preferred embodiment, eachconductor 22, having a length equal to or less than 60 cm, has a resistance of less than 25 ohms. In a more preferred embodiment, eachconductor 20, having a length equal to or less than 60 cm, has a resistance equal to or less than 10 ohms. In a most preferred embodiment, eachconductor 20, having a length equal to or less than 60 cm, has a resistance of less than 4 ohms. - While a number of material and construction options have been discussed above, it should be noted that neither the materials selected nor a construction methodology is critical to the present invention.
- The following discussion is directed to a number of examples illustrated in FIGS. 2-5. While the examples set forth a variety of variations of the present invention, it may be readily appreciated that the present invention could take any of a variety of forms and include any number of electrodes. Importantly, however, the present invention is characterized by a first electrode, or a first electrode array, that substantially encompasses or circumscribes at least one independently controlled electrode. The first electrode (or first electrode array) can operatively form an “anode guard” relative to the substantially surrounded independently controlled electrode(s). To clarify such structure, the following examples are provided.
- FIG. 2 illustrates a
laminotomy lead 100 a featuring the fundamental principle of construction of the present invention. Specifically, thepaddle structure 16 includes a plurality ofelectrodes 20, wherein oneelectrode 30 substantially surrounds anotherelectrode 40. For this embodiment, each electrode is electrically coupled to an independent terminal (not shown), which is connectable to a programmable energy source, for example, a pulse generator (not shown). The construction and arrangement of the terminals (and related conductors, which establish the desired electrical coupling) are not in themselves unique but are consistent with that described hereinabove. - Depending upon a configuration/programmability of the energy source connected to the laminotomy lead100 a, either the
electrode 30 or theelectrode 40 could operatively assume a positive polarity (with the remaining electrode assuming a negative polarity) during active delivery of electrical energy therefrom. For purposes of focusing applied electrical energy, however, theelectrode 30 assumes a positive polarity, whereby in such a condition theelectrode 30 forms an “anode guard” relative to the encompassedelectrode 40. - The
electrode 30 can be constructed in a manner and from a material consistent with that used to formelectrode 40. Alternatively, as longitudinal and transverse flexibility of thepaddle structure 16 are desirable, it is preferred that the electrode(s) 30 be formed so as to not otherwise significantly impair the inherent flexibility of thepaddle structure 16. Accordingly, theelectrode 30 can be constructed using less material—in a thickness direction—than anelectrode 40, formed from a conductive film/foil applied to the surface of thepaddle structure 16, formed through deposition of a conductive material, constructed using a coil (FIG. 3), or formed using other like processes/techniques that are well known in the art. - An anode guard functions, in part, to laterally limit an applied electrical field, which assists in reducing extraneous stimulation of surrounding neural tissue. In this regard, neural tissue at or immediately about the cathode electrode(s) is depolarized, while neural tissue relative to the anode guard is subject to hyperpolarization. Further, an anode guard in accordance with that illustrated in FIG. 2 focuses an applied electrical field from practically every direction to any cathode-electrode(s) positioned therein. Thus, for any given drive signal from a coupled energy source, the stimulation lead of the present invention can effect a deeper application of applied energy than stimulation leads of a conventional nature.
- FIG. 3 illustrates a four-channel (a “channel” represents a controllable electrical output)
laminotomy stimulation lead 100 b in accordance with the present invention. Thestimulation lead 100 b is shown having a plurality ofelectrodes 20, which includes anelectrode 30, formed from a coil, that substantially circumscribes an electrode array formed of threeelectrodes - Again, while each of the plurality of
electrodes 20 could individually function as a cathode or an anode, or placed in an OFF-state, it is intended that theelectrode 30, as an anode guard, assume a positive polarity. To this end, the form of an electric field generated using theelectrode 30 is altered/controlled through setting each of theelectrodes electrodes single electrode 40 as a cathode or a more diverse electrical field spread over two ormore electrodes 40, whereas eachelectrode 40 of such plurality functions as a cathode. - Furthermore, to the extent that the benefits of an anode guard are not required, the
electrode 30 may be placed in an OFF-state. In such operative configuration, thelaminotomy lead 100 b then functions in a manner consistent with conventional laminotomy stimulation leads. - The configuration illustrated in at least FIG. 3 enables the delivery of electrical energy to targeted nervous tissue with fewer required electrodes. Moreover, it should be noted that the narrow transverse dimension of the
laminotomy lead 100 b enables such laminotomy lead to be implanted percutaneously, if so desired, using a special insertion needle 200 that accommodates the greater dimensions of a laminotomy lead, for example, thelaminotomy lead 100 b. To this end, implantation of the present invention would be similar that described hereinabove in the context of percutaneous catheters. - FIG. 4 illustrates a
laminotomy stimulation lead 100 c in accordance with the present invention. Thestimulation lead 100 c includes a plurality ofelectrodes 20, which includes a first electrode array having a plurality ofelectrodes 30 a-30 d that substantially surrounds a second electrode array having a plurality ofelectrodes 40. - Similar to the
stimulation lead 100 b, the second electrode array of thestimulation lead 100 c is formed of a group of individual electrodes that can respectively be set as an anode, a cathode, or in an OFF-state. Although theelectrodes 40 of thestimulation lead 100 c are shown in two, staggered columns, the arrangement of theelectrodes 40 of the second electrode array is not critical to the present invention—theelectrodes 40 of the second electrode array may assume any multiple-column arrangement. - Unlike the other embodiments illustrated, the anode guard is constructed of a first electrode array that includes
electrodes 30 a-30 d. In a preferred embodiment, each electrode of the first electrode array extends for a length substantially equivalent to a comparable dimension of at least two ofelectrodes 40 of the second electrode array. Further, and generally consistent with the structures of FIGS. 2, 3, and 5, the collection ofelectrodes 30 a-30 d form an effectively continuous ring that substantially extends about the second electrode array. - Although each of the
electrodes 30 a-30 d may be electrically independent (i.e., coupled to respective conductors/terminals), allowing each respective electrode to be an anode, a cathode, or set to an OFF-state, in consideration of practical space limitations, it may be advisable to electrically couple two or more ofelectrodes 30 a-30 d. In a simplest form,electrodes 30 a-30 d are electrically linked so as to maintain the same electrical state during operation and minimize the number of conductors necessary to couple the first electrode array to an energy source. - Of a final note, depending upon the form/construction of the
electrodes 30 a-30 d, the segmented nature of the illustrated first electrode array of this embodiment would improve longitudinal flexibility of thepaddle structure 16. As additional segmentation ofelectrodes paddle structure 16, such modification is within the scope of this embodiment of the present invention. - To maintain a generally uniform electrical field between an anode guard and one or more cathode-electrodes, the distance between the one or more cathode-electrodes and the anode guard should be largely equidistant. Achieving this optimum arrangement is typically hindered by both a need that the
platform structure 16 fit easily within the narrow confines of the human epidural space and a desire that the provided electrode array(s) span a significant vertebral range of spinal nervous tissue. - While a long electrode array substantially surrounded by a single anode guard electrode (or a composite anode guard) would not be operatively ineffective, an alternative to such structure is illustrated by the
stimulation lead 100 d of FIG. 5. Specifically, theelectrodes 40 can be divided intogroups electrode group anode guard electrode - While the invention has been described herein relative to a number of particularized embodiments, it is understood that modifications of, and alternatives to, these embodiments, such modifications and alternatives realizing the advantages and benefits of this invention, will be apparent those of ordinary skill in the art having reference to this specification and its drawings. It is contemplated that such modifications and alternatives are within the scope of this invention as subsequently claimed herein, and it is intended that the scope of this invention claimed herein be limited only by the broadest interpretation of the appended claims to which the inventors are legally entitled.
Claims (22)
1. A stimulation load comprising:
a body having a first surface;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode,
wherein the plurality of electrodes includes a first electrode and a second electrode, and
wherein the second electrode substantially encircles at least the first electrode.
2. A stimulation lead in accordance with claim 1 , wherein the plurality of electrodes includes a first electrode array, which includes the first electrode, and the second electrode substantially encircles the first electrode array.
3. A stimulation lead in accordance with claim 2 , wherein the first electrode array comprises a plurality of electrodes arranged in at least two columns.
4. A stimulation lead comprising:
a plurality of terminals;
a plurality of electrodes forming at least two electrode arrays; and
a plurality of conductors,
wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode,
wherein a first electrode array of the at least two electrode arrays includes at least a first electrode and a second electrode, and the first electrode substantially circumscribes at least the second electrode.
5. A stimulation lead in accordance with claim 4 , wherein the first electrode of the first electrode array substantially circumscribes a plurality of electrodes, such plurality of electrodes including the second electrode.
6. A stimulation lead in accordance with claim 4 , wherein a second electrode array of the at least two electrode arrays includes at least a third electrode and a fourth electrode, and the third electrode substantially circumscribes at least the fourth electrode.
7. A stimulation lead in accordance with claim 6 , wherein the third electrode of the second electrode array substantially circumscribes a plurality of electrodes, such plurality of electrodes including the fourth electrode.
8-11. Canceled.
12. A stimulation lead comprising:
a plurality of terminals;
a plurality of electrodes; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode,
wherein the plurality of electrodes includes first electrode and a second electrode, and
wherein the second electrode substantially encircles at least the first electrode.
13. A method of placing a stimulation lead in a human patient, comprising the steps of:
providing a stimulation lead, the stimulation lead having:
a body;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode;
surgically accessing a site proximate to a desired stimulation lead placement site in the patient; and placing the stimulation lead at the desired stimulation lead placement site,
wherein the plurality of electrodes includes a first electrode and a second electrode, and
wherein the second electrode substantially encircles at least the first electrode.
14. A method of placing a stimulation lead in a human patient, comprising the steps of:
providing a stimulation lead the stimulation lead having:
a body;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode;
percutaneously accessing a site proximate to a desired stimulation lead placement site in the patient; and
placing the stimulation lead at the desired stimulation lead placement site,
wherein the plurality of electrodes includes a first electrode and a second electrode, and
wherein the second electrode substantially encircles at least the first electrode.
15. An epidural stimulation lead operable to provide a stimulation pattern from an applied electric field comprising:
a body having a first surface;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode, wherein the plurality of electrodes includes a first electrode and a second electrode, and wherein the second electrode substantially encircles at least the first electrode, forming an anode guard, and wherein said second electrode is coupled to an energy source that provides a positive polarity to said second electrode relative to said first electrode.
16. The epidural stimulation lead of claim 15 , wherein the first electrode comprises an array of electrodes substantially encircled by the second electrode.
17. The epidural stimulation lead of claim 16 , wherein the array of electrodes comprises said first electrode comprising at least two columns of electrodes.
18. The epidural stimulation lead of claim 16 wherein said second electrode comprises an array of electrodes that substantially encircle said first electrode.
19. A method of providing a stimulation pattern from an applied electric field with an epidural stimulation lead comprising the steps of:
coupling a plurality of terminals of said lead to an energy source wherein said lead further comprises:
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode; and
a plurality of electrodes forming at least two electrode arrays, wherein a first electrode array of the at least two electrode arrays includes at least a first electrode and a second electrode; positively biasing said first electrode relative to said second electrode, wherein said first electrode substantially circumscribes said second electrode.
20. The method of claim 19 wherein the first electrode of the first electrode array substantially circumscribes a plurality of electrodes, such plurality of electrodes including the second electrode.
21. The epidural stimulation lead of claim 19 , wherein a second electrode array of the at least two electrode arrays includes at least a third electrode and a fourth electrode, and the third electrode substantially circumscribes at least the fourth electrode.
22. The method of claim 19 , wherein the third electrode of the second electrode array substantially circumscribes a plurality of electrodes, such plurality of electrodes including the fourth electrode.
23. An epidural stimulation lead operable to provide patterned stimulation from an electric field comprising:
a plurality of terminals coupled to an energy source;
a plurality of electrodes;
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode,
wherein the plurality of electrodes includes a first electrode and a second electrode that substantially encircles said first electrode forming an anode guard.
24. A method of placing a stimulation lead in a human patient, comprising the steps of:
providing a stimulation lead, the stimulation lead having:
a body;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode;
surgically accessing a site proximate to a desired stimulation lead placement site in the patient; and
placing the stimulation lead at the desired stimulation lead placement site,
wherein the plurality of electrodes includes a first electrode and a second electrode, and
wherein the second electrode substantially encircles at least the first electrode.
25. A method of providing a stimulation pattern from an applied electric field, comprising the steps of:
providing an epidural stimulation lead, the stimulation lead further comprising:
a body;
a plurality of terminals;
a plurality of electrodes positioned relative to the first surface of the body; and
a plurality of conductors, wherein a conductor electrically couples one terminal of the plurality of terminals with at least one electrode;
percutaneously accessing a site proximate to a desired stimulation lead placement site in the patient;
placing the stimulation lead at the desired stimulation lead placement site, wherein the plurality of electrodes includes a first electrode and a second electrode, and
coupling said epidural stimulation lead to an energy source wherein said energy source provides a positive voltage to said second electrode relative to said first electrode, wherein the second electrode substantially encircles at least the first electrode.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/844,672 US20040210291A1 (en) | 2000-08-10 | 2004-05-13 | Spinal cord stimulation lead with an anode guard |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/635,910 US6754539B1 (en) | 2000-08-10 | 2000-08-10 | Spinal cord stimulation lead with an anode guard |
US10/844,672 US20040210291A1 (en) | 2000-08-10 | 2004-05-13 | Spinal cord stimulation lead with an anode guard |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/635,910 Division US6754539B1 (en) | 2000-08-10 | 2000-08-10 | Spinal cord stimulation lead with an anode guard |
Publications (1)
Publication Number | Publication Date |
---|---|
US20040210291A1 true US20040210291A1 (en) | 2004-10-21 |
Family
ID=24549616
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/635,910 Expired - Lifetime US6754539B1 (en) | 2000-08-10 | 2000-08-10 | Spinal cord stimulation lead with an anode guard |
US10/844,672 Abandoned US20040210291A1 (en) | 2000-08-10 | 2004-05-13 | Spinal cord stimulation lead with an anode guard |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/635,910 Expired - Lifetime US6754539B1 (en) | 2000-08-10 | 2000-08-10 | Spinal cord stimulation lead with an anode guard |
Country Status (3)
Country | Link |
---|---|
US (2) | US6754539B1 (en) |
AU (1) | AU6537801A (en) |
WO (1) | WO2002013903A2 (en) |
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006113593A2 (en) * | 2005-04-14 | 2006-10-26 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation lead, system, and method |
US20070118198A1 (en) * | 2005-11-07 | 2007-05-24 | Prager Joshua P | Neurostimulation lead with concentric electrodes |
US20070179579A1 (en) * | 2006-01-26 | 2007-08-02 | Feler Claudio A | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US20080103534A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical elongated member including fixation elements along an interior surface |
US20080103574A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical lead including a directional electrode and fixation elements along an interior surface |
WO2008055097A3 (en) * | 2006-10-31 | 2008-08-21 | Medtronic Inc | Implantable medical lead including a directional electrode and fixation elements along an interior surface |
US7974707B2 (en) | 2007-01-26 | 2011-07-05 | Cyberonics, Inc. | Electrode assembly with fibers for a medical device |
US8180462B2 (en) * | 2006-04-18 | 2012-05-15 | Cyberonics, Inc. | Heat dissipation for a lead assembly |
US8478428B2 (en) | 2010-04-23 | 2013-07-02 | Cyberonics, Inc. | Helical electrode for nerve stimulation |
US8478420B2 (en) | 2006-07-12 | 2013-07-02 | Cyberonics, Inc. | Implantable medical device charge balance assessment |
US8483846B2 (en) | 2006-07-26 | 2013-07-09 | Cyberonics, Inc. | Multi-electrode assembly for an implantable medical device |
US8612009B2 (en) | 2006-01-26 | 2013-12-17 | Advanced Neuromodulation Systems, Inc. | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US8805519B2 (en) | 2010-09-30 | 2014-08-12 | Nevro Corporation | Systems and methods for detecting intrathecal penetration |
US8868203B2 (en) | 2007-10-26 | 2014-10-21 | Cyberonics, Inc. | Dynamic lead condition detection for an implantable medical device |
US8942798B2 (en) | 2007-10-26 | 2015-01-27 | Cyberonics, Inc. | Alternative operation mode for an implantable medical device based upon lead condition |
US10980999B2 (en) | 2017-03-09 | 2021-04-20 | Nevro Corp. | Paddle leads and delivery tools, and associated systems and methods |
US11420045B2 (en) | 2018-03-29 | 2022-08-23 | Nevro Corp. | Leads having sidewall openings, and associated systems and methods |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6895283B2 (en) * | 2000-08-10 | 2005-05-17 | Advanced Neuromodulation Systems, Inc. | Stimulation/sensing lead adapted for percutaneous insertion |
US7203548B2 (en) * | 2002-06-20 | 2007-04-10 | Advanced Bionics Corporation | Cavernous nerve stimulation via unidirectional propagation of action potentials |
US7797057B2 (en) * | 2002-10-23 | 2010-09-14 | Medtronic, Inc. | Medical paddle lead and method for spinal cord stimulation |
US7499755B2 (en) | 2002-10-23 | 2009-03-03 | Medtronic, Inc. | Paddle-style medical lead and method |
AU2003286590A1 (en) * | 2003-10-02 | 2005-05-19 | Medtronic, Inc. | Medical lead system with flat electrode paddle |
US7383090B2 (en) * | 2003-10-20 | 2008-06-03 | Greatbatch Ltd. | Connection for a coiled lead to an electrical contact for an implantable medical device |
US7437197B2 (en) | 2003-10-23 | 2008-10-14 | Medtronic, Inc. | Medical lead and manufacturing method therefor |
US9205261B2 (en) | 2004-09-08 | 2015-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Neurostimulation methods and systems |
WO2006029257A2 (en) * | 2004-09-08 | 2006-03-16 | Spinal Modulation Inc. | Neurostimulation methods and systems |
US20120277839A1 (en) | 2004-09-08 | 2012-11-01 | Kramer Jeffery M | Selective stimulation to modulate the sympathetic nervous system |
US8214047B2 (en) * | 2004-09-27 | 2012-07-03 | Advanced Neuromodulation Systems, Inc. | Method of using spinal cord stimulation to treat gastrointestinal and/or eating disorders or conditions |
US7395119B2 (en) * | 2005-05-19 | 2008-07-01 | Cvrx, Inc. | Implantable electrode assembly having reverse electrode configuration |
US20070073354A1 (en) * | 2005-09-26 | 2007-03-29 | Knudson Mark B | Neural blocking therapy |
US7567840B2 (en) | 2005-10-28 | 2009-07-28 | Cyberonics, Inc. | Lead condition assessment for an implantable medical device |
US8027718B2 (en) * | 2006-03-07 | 2011-09-27 | Mayo Foundation For Medical Education And Research | Regional anesthetic |
US20070213796A1 (en) * | 2006-03-10 | 2007-09-13 | Mcginnis William J | Ring electrode |
US7617006B2 (en) * | 2006-04-28 | 2009-11-10 | Medtronic, Inc. | Medical electrical lead for spinal cord stimulation |
US7515968B2 (en) * | 2006-04-28 | 2009-04-07 | Medtronic, Inc. | Assembly method for spinal cord stimulation lead |
US7742824B2 (en) * | 2006-08-21 | 2010-06-22 | Medtronic, Inc. | Medical electrode mounting |
US7765011B2 (en) * | 2006-08-21 | 2010-07-27 | Medtronic, Inc. | Assembly methods for medical electrical leads |
US7738966B2 (en) | 2006-08-21 | 2010-06-15 | Medtronic, Inc. | Features for routing conductors in medical electrical lead electrode assemblies |
WO2008070806A2 (en) | 2006-12-06 | 2008-06-12 | Spinal Modulation, Inc. | Hard tissue anchors and delivery devices |
WO2008070808A2 (en) | 2006-12-06 | 2008-06-12 | Spinal Modulation, Inc. | Expandable stimulation leads and methods of use |
US9314618B2 (en) | 2006-12-06 | 2016-04-19 | Spinal Modulation, Inc. | Implantable flexible circuit leads and methods of use |
JP5414531B2 (en) | 2006-12-06 | 2014-02-12 | スパイナル・モデュレーション・インコーポレイテッド | Delivery device and systems and methods for stimulating neural tissue at multiple spinal levels |
US9044592B2 (en) | 2007-01-29 | 2015-06-02 | Spinal Modulation, Inc. | Sutureless lead retention features |
WO2008134059A1 (en) * | 2007-04-30 | 2008-11-06 | Medtronic, Inc. | Shifting of electrical stimulation electrode combinations among differently sized electrode arrays |
EP2152356A1 (en) * | 2007-04-30 | 2010-02-17 | Medtronic, Inc. | Parameter-directed shifting of electrical stimulation electrode combinations |
US8239044B1 (en) | 2007-12-07 | 2012-08-07 | Advanced Neuromodulation Systems, Inc. | Stimulation lead for steering current for stimulation of patient tissue, method of stimulating patient tissue, and implantable medical system |
US7941227B2 (en) * | 2008-09-03 | 2011-05-10 | Boston Scientific Neuromodulation Corporation | Implantable electric stimulation system and methods of making and using |
US9504818B2 (en) | 2008-09-04 | 2016-11-29 | Boston Scientific Neuromodulation Corporation | Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering |
US9717910B2 (en) | 2008-09-04 | 2017-08-01 | Boston Scientific Neuromodulation Corporation | Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering |
US9056197B2 (en) | 2008-10-27 | 2015-06-16 | Spinal Modulation, Inc. | Selective stimulation systems and signal parameters for medical conditions |
US8255057B2 (en) | 2009-01-29 | 2012-08-28 | Nevro Corporation | Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions |
WO2010111358A2 (en) | 2009-03-24 | 2010-09-30 | Spinal Modulation, Inc. | Pain management with stimulation subthreshold to parasthesia |
CA2761778A1 (en) | 2009-05-15 | 2010-11-18 | Spinal Modulation, Inc. | Methods, systems and devices for neuromodulating spinal anatomy |
US8452414B2 (en) * | 2009-09-29 | 2013-05-28 | Medtronic, Inc. | Steering stimulation current by employing steering current |
EP2568904B1 (en) | 2010-05-10 | 2019-10-02 | Spinal Modulation Inc. | Device for reducing migration |
US8965482B2 (en) | 2010-09-30 | 2015-02-24 | Nevro Corporation | Systems and methods for positioning implanted devices in a patient |
CA2825763A1 (en) | 2011-02-02 | 2012-08-09 | Spinal Modulation, Inc. | Devices, systems and methods for the targeted treatment of movement disorders |
WO2013016343A1 (en) * | 2011-07-25 | 2013-01-31 | Kipke Daryl R | Distributed neural stimulation array system |
US9308022B2 (en) | 2012-12-10 | 2016-04-12 | Nevro Corporation | Lead insertion devices and associated systems and methods |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4125116A (en) * | 1977-02-14 | 1978-11-14 | The Johns Hopkins University | Human tissue stimulation electrode structure |
US6038480A (en) * | 1996-04-04 | 2000-03-14 | Medtronic, Inc. | Living tissue stimulation and recording techniques with local control of active sites |
US6236892B1 (en) * | 1999-10-07 | 2001-05-22 | Claudio A. Feler | Spinal cord stimulation lead |
US6505078B1 (en) * | 1996-04-04 | 2003-01-07 | Medtronic, Inc. | Technique for adjusting the locus of excitation of electrically excitable tissue |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3004126C2 (en) * | 1980-02-05 | 1986-06-05 | Schmid, geb.Bühl, Annemarie, 7914 Pfaffenhofen | Bioelectric skin contact electrode |
US4379462A (en) | 1980-10-29 | 1983-04-12 | Neuromed, Inc. | Multi-electrode catheter assembly for spinal cord stimulation |
US5119832A (en) | 1989-07-11 | 1992-06-09 | Ravi Xavier | Epidural catheter with nerve stimulators |
US5417719A (en) * | 1993-08-25 | 1995-05-23 | Medtronic, Inc. | Method of using a spinal cord stimulation lead |
US5501703A (en) | 1994-01-24 | 1996-03-26 | Medtronic, Inc. | Multichannel apparatus for epidural spinal cord stimulator |
US5935082A (en) * | 1995-01-26 | 1999-08-10 | Cambridge Heart, Inc. | Assessing cardiac electrical stability |
US5895416A (en) * | 1997-03-12 | 1999-04-20 | Medtronic, Inc. | Method and apparatus for controlling and steering an electric field |
US6205361B1 (en) * | 1998-02-10 | 2001-03-20 | Advanced Bionics Corporation | Implantable expandable multicontact electrodes |
-
2000
- 2000-08-10 US US09/635,910 patent/US6754539B1/en not_active Expired - Lifetime
-
2001
- 2001-06-06 AU AU6537801A patent/AU6537801A/en active Pending
- 2001-06-06 WO PCT/US2001/018311 patent/WO2002013903A2/en active Application Filing
-
2004
- 2004-05-13 US US10/844,672 patent/US20040210291A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4125116A (en) * | 1977-02-14 | 1978-11-14 | The Johns Hopkins University | Human tissue stimulation electrode structure |
US6038480A (en) * | 1996-04-04 | 2000-03-14 | Medtronic, Inc. | Living tissue stimulation and recording techniques with local control of active sites |
US6505078B1 (en) * | 1996-04-04 | 2003-01-07 | Medtronic, Inc. | Technique for adjusting the locus of excitation of electrically excitable tissue |
US6236892B1 (en) * | 1999-10-07 | 2001-05-22 | Claudio A. Feler | Spinal cord stimulation lead |
Cited By (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7603178B2 (en) | 2005-04-14 | 2009-10-13 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation lead, system, and method |
US20070060991A1 (en) * | 2005-04-14 | 2007-03-15 | North Richard B | Electrical stimulation lead, system, and method |
WO2006113593A3 (en) * | 2005-04-14 | 2007-07-12 | Advanced Neuromodulation Sys | Electrical stimulation lead, system, and method |
WO2006113593A2 (en) * | 2005-04-14 | 2006-10-26 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation lead, system, and method |
US8478427B2 (en) | 2005-04-14 | 2013-07-02 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation lead, system, and method |
US20090326594A1 (en) * | 2005-04-14 | 2009-12-31 | North Richard B | Electrical stimulation lead, system, and method |
US20070118198A1 (en) * | 2005-11-07 | 2007-05-24 | Prager Joshua P | Neurostimulation lead with concentric electrodes |
US8615300B2 (en) | 2006-01-26 | 2013-12-24 | Advanced Neuromodulation Systems, Inc. | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US7979133B2 (en) | 2006-01-26 | 2011-07-12 | Advanced Neuromodulation Systems, Inc. | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US20070179579A1 (en) * | 2006-01-26 | 2007-08-02 | Feler Claudio A | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US8612009B2 (en) | 2006-01-26 | 2013-12-17 | Advanced Neuromodulation Systems, Inc. | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
WO2007087626A2 (en) * | 2006-01-26 | 2007-08-02 | Advanced Neuromodulation Systems, Inc. | Method of neurosimulation of distinct neural structures using single paddle lead |
WO2007087626A3 (en) * | 2006-01-26 | 2008-02-14 | Advanced Neuromodulation Sys | Method of neurosimulation of distinct neural structures using single paddle lead |
US20100030300A1 (en) * | 2006-01-26 | 2010-02-04 | Feler Claudio A | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US20100030310A1 (en) * | 2006-01-26 | 2010-02-04 | Feler Claudio A | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US7979131B2 (en) | 2006-01-26 | 2011-07-12 | Advanced Neuromodulation Systems, Inc. | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation |
US8180462B2 (en) * | 2006-04-18 | 2012-05-15 | Cyberonics, Inc. | Heat dissipation for a lead assembly |
US8478420B2 (en) | 2006-07-12 | 2013-07-02 | Cyberonics, Inc. | Implantable medical device charge balance assessment |
US8483846B2 (en) | 2006-07-26 | 2013-07-09 | Cyberonics, Inc. | Multi-electrode assembly for an implantable medical device |
US7684873B2 (en) | 2006-10-31 | 2010-03-23 | Medtronic, Inc. | Implantable medical lead including a directional electrode and fixation elements along an interior surface |
US7904149B2 (en) | 2006-10-31 | 2011-03-08 | Medtronic, Inc. | Implantable medical elongated member including fixation elements along an interior surface |
US20080103574A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical lead including a directional electrode and fixation elements along an interior surface |
US20080103534A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical elongated member including fixation elements along an interior surface |
WO2008055097A3 (en) * | 2006-10-31 | 2008-08-21 | Medtronic Inc | Implantable medical lead including a directional electrode and fixation elements along an interior surface |
US20080103569A1 (en) * | 2006-10-31 | 2008-05-01 | Medtronic, Inc. | Implantable medical elongated member including fixation elements along an interior surface |
US8688238B2 (en) * | 2006-10-31 | 2014-04-01 | Medtronic, Inc. | Implantable medical elongated member including fixation elements along an interior surface |
US8295946B2 (en) | 2007-01-26 | 2012-10-23 | Cyberonics, Inc. | Electrode assembly with fibers for a medical device |
US7974707B2 (en) | 2007-01-26 | 2011-07-05 | Cyberonics, Inc. | Electrode assembly with fibers for a medical device |
US8868203B2 (en) | 2007-10-26 | 2014-10-21 | Cyberonics, Inc. | Dynamic lead condition detection for an implantable medical device |
US8942798B2 (en) | 2007-10-26 | 2015-01-27 | Cyberonics, Inc. | Alternative operation mode for an implantable medical device based upon lead condition |
US8478428B2 (en) | 2010-04-23 | 2013-07-02 | Cyberonics, Inc. | Helical electrode for nerve stimulation |
US8805519B2 (en) | 2010-09-30 | 2014-08-12 | Nevro Corporation | Systems and methods for detecting intrathecal penetration |
US9358388B2 (en) | 2010-09-30 | 2016-06-07 | Nevro Corporation | Systems and methods for detecting intrathecal penetration |
US10279183B2 (en) | 2010-09-30 | 2019-05-07 | Nevro Corp. | Systems and methods for detecting intrathecal penetration |
US10980999B2 (en) | 2017-03-09 | 2021-04-20 | Nevro Corp. | Paddle leads and delivery tools, and associated systems and methods |
US11759631B2 (en) | 2017-03-09 | 2023-09-19 | Nevro Corp. | Paddle leads and delivery tools, and associated systems and methods |
US11420045B2 (en) | 2018-03-29 | 2022-08-23 | Nevro Corp. | Leads having sidewall openings, and associated systems and methods |
Also Published As
Publication number | Publication date |
---|---|
WO2002013903A3 (en) | 2002-07-04 |
AU6537801A (en) | 2002-02-25 |
WO2002013903A2 (en) | 2002-02-21 |
US6754539B1 (en) | 2004-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6754539B1 (en) | Spinal cord stimulation lead with an anode guard | |
US6895283B2 (en) | Stimulation/sensing lead adapted for percutaneous insertion | |
US6236892B1 (en) | Spinal cord stimulation lead | |
US20210187284A1 (en) | Implantable lead with flexible paddle electrode array | |
EP2822644B1 (en) | Flexible paddle lead body with scored surfaces | |
US7979131B2 (en) | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation | |
US20080228250A1 (en) | Paddle lead comprising opposing diagonal arrangements of electrodes and method for using the same | |
US8612009B2 (en) | Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation | |
US9084882B1 (en) | Leads for neurostimulation and methods of assembling same | |
EP2822643B1 (en) | Paddle lead body with insertion tab | |
AU2002326493A1 (en) | Stimulation/sensing lead adapted for percutaneous insertion |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ADVANCED NEUROMODULATION SYSTEMS, INC., TEXAS Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ERICKSON, JOHN H.;DREES, SCOTT F.;REEL/FRAME:015181/0683 Effective date: 20001027 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |