|Número de publicación||US20060149379 A1|
|Tipo de publicación||Solicitud|
|Número de solicitud||US 11/282,910|
|Fecha de publicación||6 Jul 2006|
|Fecha de presentación||18 Nov 2005|
|Fecha de prioridad||21 Jul 2000|
|También publicado como||DE60141653D1, EP2108323A2, EP2108323A3, US7226481, US20020068974, US20040073308, US20140067066, WO2003007853A1|
|Número de publicación||11282910, 282910, US 2006/0149379 A1, US 2006/149379 A1, US 20060149379 A1, US 20060149379A1, US 2006149379 A1, US 2006149379A1, US-A1-20060149379, US-A1-2006149379, US2006/0149379A1, US2006/149379A1, US20060149379 A1, US20060149379A1, US2006149379 A1, US2006149379A1|
|Inventores||Stephen Kuslich, John Kuslich|
|Cesionario original||Spineology, Inc.|
|Exportar cita||BiBTeX, EndNote, RefMan|
|Citas de patentes (99), Citada por (59), Clasificaciones (64), Eventos legales (3)|
|Enlaces externos: USPTO, Cesión de USPTO, Espacenet|
This application is a divisional application of U.S. patent Ser. No. 10/440,036, filed May 16, 2003, which claims priority to U.S. patent application Ser. No. 09/909,667, filed Jul. 20, 2001, which claims priority to U.S. Provisional Application No. 60/219,853 filed Jul. 21, 2000, the entirety of which is incorporated herein by reference.
This invention relates to methods and devices for correcting bone abnormalities and involves the use of a surgical mesh bag which is inserted into a prepared cavity in bone. The bag is inflated using bone replacement material to expand and fill the cavity.
U.S. Pat. Nos. 5,549,679 and 5,571,189 to Kuslich, describe a device and method for stabilizing the spinal segment with an expandable, porous fabric implant for insertion into the interior of a reamed out disc which is packed with material to facilitate bony fusion. In the present invention, a similar bag is used to correct bone abnormalities including, but not limited to, bone tumors and cysts, tibial plateau fractures, avascular necrosis of the femoral head and compression fractures of the spine.
U.S. Pat. Nos. 5,108,404 and 4,969,888 to Scholten et al., describe a system for fixing osteoporotic bone using an inflatable balloon which compacts the bone to form a cavity into which bone cement is injected after the balloon is withdrawn. The invention requires the use of fluoroscopy to monitor the injection and to help guard against cement leakage through fissures in bone. Unfortunately, such leakage is known to occur in spite of these precautions. Since such leakage may cause serious injury, including paralysis, an improved device and method is needed.
U.S. Pat. No. 5,972,015 to Scribner et al., describes a system of deploying a catheter tube into the interior of a vertebra and expanding a specially configured nonporous balloon therewithin to compact cancellous bone to form a cavity. The Scribner patent approach utilizes a non-porous balloon which is inflated within the bone to cause compression. The cavity thus formed, may then be filled with bone cement. Unfortunately, the bag used by Scribner may be ruptured during expansion to compact cancellous bone due to sharp projections found within the cavity to be expanded. Filling the cavity eventually formed could allow leakage of bone cement out of the bone against vessels or nerves which may cause undesirable complications.
The present invention involves an improvement of all of the previous techniques and avoids complications that could occur with the system of U.S. Pat. No. 5,972,015.
All U.S. patents, applications and all other published documents mentioned anywhere in this application are incorporated herein by reference in their entirety.
The art described in this section is not intended to constitute an admission that any patent, publication or other information referred to herein is “prior art” with respect to this invention, unless specifically designated as such. In addition, this section should not be construed to mean that a search has been made or that no other pertinent information as defined in 37 C.F.R. § 1.56(a) exists.
The invention provides a method of correcting numerous bone abnormalities including bone tumors and cysts, avascular necrosis of the femoral head, tibial plateau fractures and compression fractures of the spine. The abnormality may be corrected by first accessing and boring into the damaged tissue or bone and reaming out the damaged and/or diseased area using any of the presently accepted procedures, or the damaged area may be prepared by expanding a bag within the damaged bone to compact cancellous bone. After removal and/or compaction of the damaged tissue the bone must be stabilized.
In cases in which the bone is to be compacted, the methods and devices of this invention employ a catheter tube attached to an inflatable porous fabric bag as described in U.S. Pat. Nos. 5,549,679 and 5,571,189 to Kuslich, the disclosures of which are incorporated herein by reference. Those bags may be inflated with less fear of puncture and leakage of the inflation medium than thin walled rubber balloons. They may also be used over a Scribner balloon to protect the balloon from breakage and eventually seepage.
The devices of U.S. Pat. Nos. 5,549,679 and 5,571,189 to Kuslich, additionally provide the surgeon with the advantage of safely skipping the first balloon inflation steps of Scribner and Scholten, by expanding the bag through introduction of fill material, such as a bone repair medium thereby correcting the bony defect and deformity and stabilizing it in one step of the procedure.
As indicated above, the damaged bone may be removed by any conventional reamer. Examples of reamers are described in U.S. Pat. No. 5,015,255; U.S. patent application Ser. No. 09/782,176, to Kuslich et al., entitled “Expandable Reamer” and filed Feb. 13, 2001; and U.S. patent application Ser. No. 09/827,202 to Peterson et al., entitled “Circumferential Resecting Reamer Tool,” filed Apr. 5, 2001. Other examples of reamers are known and may be used. After the damaged bone or tissue has been removed, bone repair medium may then be inserted into the cavity thus formed, via a catheter and expandable fabric bag as described in U.S. Pat. Nos. 5,549,679 and 5,571,189.
Alternatively, either a smaller than desired cavity may be formed into the bone to be enlarged by compaction or the cavity may be formed only by compaction through introduction of fill material into the bag. In either case, the bag may be positioned over the inflation balloon which is then inflated within the bone site to provide the degree of compaction required. The bag may then be filled with fill material, such as bone repair medium while the balloon remains in place within the bag. Alternatively, the balloon may be removed from the bag prior to filing the bag.
A detailed description of the invention is hereafter described with specific reference being made to the drawings in which:
In the following detailed description, similar reference numerals are used to depict like elements in the various figures.
As previously mentioned, the damaged portion of the vertebra 10 may be compacted in addition to or instead of being reamed out. In
Bone replacement material 19 may be one or more of the following, or any other biocompatible material judged to have the desired physiologic response:
A) Demineralized bone material, morselized bone graft, cortical, cancellous, or cortico-cancellous, including autograft, allograft, or xenograft;
B) Any bone graft substitute or combination of bone graft substitutes, or combinations of bone graft and bone graft substitutes, or bone inducing substances, including but not limited to: Tricalcium phosphates, Tricalcium sulfates, Tricalcium carbonates, hydroxyapatite, bone morphogenic protein, calcified and/or decalcified bone derivative; and
C) Bone cements, such as ceramic and polymethylmethacrylate bone cements.
The bone replacement material is inserted into the bag 22 via a needle, catheter 20 or other type of fill tool. The bone replacement material expands the bag to the limits of the cavity 16.
The inventive bag 22 may be a small fabric bag, from about one to about four cm in diameter, being roughly spherical in shape, although other elliptical shapes and other geometric shapes may be used. The bag is pliable and malleable before its interior space 21 is filled with the contents to be described. The material of the bag 22 may be configured to take on the shape of the cavity in which the bag is placed. While in this initial condition, the bag may be passed, uninflated, through a relatively small tube or portal, perhaps about three mm to about one cm in diameter.
The bag 22, such as may best be seen in
One or more of the pores 25 may be used as a fill opening 27, wherein the fabric 23 may be manipulated to enlarge a pore to a diameter potentially greater than 5 mm but no more than about 1 cm. Preferably, the fill opening 27 is less than about 5 mm in diameter. Such a pore/fill opening 27 is sufficiently large to allow a catheter, needle, fill tube or other device for inserting or injecting fill material to pass through the fabric 23 and into the interior 21 of the bag 22 without damaging the integrity of the bag 22.
When the bag 22 is fully filled with fill material, the bag will form a self-retaining shape which substantially fills the cavity 16. Once sufficiently full, the fill tool used to place fill material into the bag interior 21 is removed from the opening 27. Where the opening 27 is not a pore 25 but rather a separate and distinct opening in the bag 22, the opening 27 may have a set diameter which requires sealing such as by tying, fastening, welding, gluing or other means of closing the opening 27 after the bag has been filled. Where the opening 27 is a pore 25, upon removal of the catheter or fill tool from the opening 27 the fabric 23 will contract to reduce the diameter of the opening 27 to be substantially similar to that of the other pores 25.
The size and density of the pores determine the ease or difficulty with which materials may pass through the mesh. For instance, very small pores (<0.5 mm) would prohibit passage of all but the smallest particles and liquids. The pore size and density could be controlled in the manufacturing process, such that the final product would be matched to the needs of the surgeon. For example, if methylmethacrylate bone cement were to be used, the pore size would need to be very small, such as about less than 0.5 mm to about 1.0 mm, whereas, when bone graft or biocompatible ceramic granules are used, pore sizes ranging from about 1.0 mm to about 5.0 mm or more may be allowed. The fact that the fabric 23 is properly porous would allow it to restrict potentially dangerous flow of the fill material outside the confines of the bag.
The fabric is light, biocompatible, flexible and easily handled, and has very good tensile strength, and thus is unlikely to rip or tear during insertion and inflation. When the device is inflated, the device expands to fill a previously excavated cavity 16.
The use of the term “fabric” herein is meant to include the usual definition of that term and to include any material that functions like a fabric, that is, the “fabric” of the invention must have a plurality of pores 25 through which material and fluid flow is allowed under the terms as described, and the “fabric” must be flexible enough to allow it to be collapsed and inserted into an opening smaller than the inflated bag size.
The bag 22 need not be woven and may be molded or otherwise formed as is well known in the art. The preferred material may provide the ability to tailor bioabsorbance rates. Any suture-type material used medically may be used to form the bag 22. The bag may be formed of plastic or even metal. In at least one embodiment, bag 22 is formed using a combination of resorbable and/or nonresorbable thread. Bag 22 may include a fill opening 27 which may be a bushing that could be a bioabsorbable and/or nonbioabsorbable plastic, ceramic or metal. The opening 27 may also be hydroxyapatite, or it could be plastic or metal. The opening 27 may also be characterized as a pore 25, wherein a pore 25 of the fabric 23 has been expanded to allow a catheter 20 or other fill device to pass into the interior 21 of the bag 22. The bag 22 could be formed from a solid material to which perforations are added. The bag 22 may be partially or totally absorbable, metal, plastic, woven, solid, film or an extruded balloon.
In embodiments of the present invention a damaged tissue of a body, such as a vertebra 10 may be treated in accordance with the following procedures such as are depicted in FIGS. 1-9:
Initially, the vertebra 10 needing repair is surgically exposed by forming at least one cavity 16. The cavity or cavities 16 may be formed by several different means such as by reaming. Reaming may be accomplished by several means such as including the use of a reamer 14 such as, for example, the Kuslich Expandable Reamer, U.S. Pat. No. 5,015,255, the entire content of which is incorporated herein by reference. Next, the unexpanded mesh bag or Expandable Fabric Bag Device (EFBD) 22 is inserted into the cavity or cavities via catheter 20 or other means. At some point, the fill material 19 is prepared for insertion or injection into the EFBD 22. Following preparation of the fill material 19, the material is injected or otherwise inserted into the bag 22 using sufficient pressure to fill the bag 22 to its expanded state, thus producing rigidity and tension within the cavity or cavities 16 to reach the degree of correction required by virtue of the compression fractures. Finally, the fill opening 27 is closed to prevent egress of inflation material 19.
As may best be seen in
If desired, the expandable fabric bag 22 may be used as the sole inflation device, eliminating the Scribner et al. balloon 30 if the fabric porosity is tight and the inflation media is reasonably viscous.
While many of the previous embodiments have described the use of the bag 22 for repair of tissue such as a spinal body, in
In an alternative embodiment, the Scribner et al. balloon, as previously described, may also be used with the bag 22 for repair of the femoral head 40.
Turning to an embodiment of the invention shown in
Other tissue and bone abnormalities may also be treated with the inventive methods and bag 22 described herein. The present invention is not limited to only treatment of spinal bodies, femoral heads, and tibial plateaus. The bag 22 and the methods of treatment described herein, may be utilized throughout a mammalian body to treat many types of bone and tissue abnormalities including those described herein as well as others.
In addition to being directed to the specific combinations of features claimed below, the invention is also directed to embodiments having other combinations of the dependent features claimed below and other combinations of the features described above.
The above disclosure is intended to be illustrative and not exhaustive. This description will suggest many variations and alternatives to one of ordinary skill in this art. All these alternatives and variations are intended to be included within the scope of the claims where the term “comprising” means “including, but not limited to.” Those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the claims.
Further, the particular features presented in the dependent claims can be combined with each other in other manners within the scope of the invention such that the invention should be recognized as also specifically directed to other embodiments having any other possible combination of the features of the dependent claims. For instance, for purposes of claim publication, any dependent claim which follows should be taken as alternatively written in a multiple dependent form from all prior claims which possess all antecedents referenced in such dependent claim if such multiple dependent format is an accepted format within the jurisdiction (e.g., each claim depending directly from claim 1 should be alternatively taken as depending from all previous claims). In jurisdictions where multiple dependent claim formats are restricted, the following dependent claims should each be also taken as alternatively written in each singly dependent claim format which creates a dependency from a prior antecedent-possessing claim other than the specific claim listed in such dependent claim below (e.g., claim 3 may be taken as alternatively dependent from claim 2; claim 5 may be taken as alternatively dependent on claim 3, claim 6 may be taken as alternatively dependent from claim 3; claim 7 may be taken as alternatively dependent from claims 3, 5 or 6; etc.).
|Patente citada||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US376477 *||17 Ene 1888||Stillwell habcoujrt|
|US817042 *||6 Feb 1905||3 Abr 1906||Thomas Burns||Boring-tool, reamer, and the like.|
|US1409825 *||27 Jul 1920||14 Mar 1922||Brush Leroy E||Expansible reamer|
|US2077804 *||19 May 1936||20 Abr 1937||Morrison Gordon Monroe||Device for treating fractures of the neck of the femur|
|US3426364 *||25 Ago 1966||11 Feb 1969||Colorado State Univ Research F||Prosthetic appliance for replacing one or more natural vertebrae|
|US3554192 *||23 Jul 1968||12 Ene 1971||Orthopedic Equipment Co||Medullary space drill|
|US3633583 *||22 Ago 1969||11 Ene 1972||Fishbein Meyer||Orthopedic single-blade bone cutter|
|US3867728 *||5 Abr 1973||25 Feb 1975||Cutter Lab||Prosthesis for spinal repair|
|US4011602 *||6 Oct 1975||15 Mar 1977||Battelle Memorial Institute||Porous expandable device for attachment to bone tissue|
|US4013071 *||11 Nov 1975||22 Mar 1977||Lior Rosenberg||Fasteners particularly useful as orthopedic screws|
|US4140432 *||25 Oct 1977||20 Feb 1979||Heinrich Heule||Deburring tool|
|US4309777 *||13 Nov 1980||12 Ene 1982||Patil Arun A||Artificial intervertebral disc|
|US4369769 *||13 Jun 1980||25 Ene 1983||Edwards Charles C||Spinal fixation device and method|
|US4430760 *||18 Dic 1981||14 Feb 1984||Collagen Corporation||Nonstress-bearing implantable bone prosthesis|
|US4497075 *||1 Mar 1982||5 Feb 1985||Mitsubishi Mining & Cement Co., Ltd.||Filler for filling in defects or hollow portions of bones|
|US4501269 *||21 Feb 1984||26 Feb 1985||Washington State University Research Foundation, Inc.||Process for fusing bone joints|
|US4573448 *||5 Oct 1983||4 Mar 1986||Pilling Co.||Method for decompressing herniated intervertebral discs|
|US4636217 *||23 Abr 1985||13 Ene 1987||Regents Of The University Of Minnesota||Anterior spinal implant|
|US4644951 *||16 Sep 1985||24 Feb 1987||Concept, Inc.||Vacuum sleeve for a surgical appliance|
|US4646738 *||5 Dic 1985||3 Mar 1987||Concept, Inc.||Rotary surgical tool|
|US4653481 *||18 Jun 1986||31 Mar 1987||Howland Robert S||Advanced spine fixation system and method|
|US4716893 *||23 Dic 1985||5 Ene 1988||Artur Fischer||Bone fastener|
|US4722338 *||12 Dic 1983||2 Feb 1988||Daniel Farley||Medical instrument for removing bone|
|US4733663 *||2 Jul 1986||29 Mar 1988||Farley Daniel K||Medical instrument for removing bone|
|US4796612 *||6 Ago 1986||10 Ene 1989||Reese Hewitt W||Bone clamp and method|
|US4904260 *||25 Jul 1988||27 Feb 1990||Cedar Surgical, Inc.||Prosthetic disc containing therapeutic material|
|US4990148 *||13 Ene 1989||5 Feb 1991||Codman & Shurtleff, Inc.||Thin footplate rongeur|
|US5176678 *||14 Mar 1991||5 Ene 1993||Tsou Paul M||Orthopaedic device with angularly adjustable anchor attachments to the vertebrae|
|US5176680 *||8 Feb 1991||5 Ene 1993||Vignaud Jean Louis||Device for the adjustable fixing of spinal osteosynthesis rods|
|US5190543 *||25 Nov 1991||2 Mar 1993||Synthes (U.S.A.)||Anchoring device|
|US5192326 *||9 Sep 1991||9 Mar 1993||Pfizer Hospital Products Group, Inc.||Hydrogel bead intervertebral disc nucleus|
|US5275600 *||5 Oct 1992||4 Ene 1994||Zimmer, Inc.||Telescoping rod to rod coupler for a spinal system|
|US5282801 *||17 Feb 1993||1 Feb 1994||Danek Medical, Inc.||Top tightening clamp assembly for a spinal fixation system|
|US5282863 *||24 Jul 1992||1 Feb 1994||Charles V. Burton||Flexible stabilization system for a vertebral column|
|US5484441 *||23 Oct 1991||16 Ene 1996||Koros; Tibor||Rongeur surgical instrument|
|US5490860 *||8 Dic 1993||13 Feb 1996||Sofamor Danek Properties, Inc.||Portable power cutting tool|
|US5501706 *||29 Nov 1994||26 Mar 1996||Wildflower Communications, Inc.||Medical implant structure and method for using the same|
|US5716416 *||10 Sep 1996||10 Feb 1998||Lin; Chih-I||Artificial intervertebral disk and method for implanting the same|
|US5865845 *||5 Mar 1996||2 Feb 1999||Thalgott; John S.||Prosthetic intervertebral disc|
|US5865848 *||12 Sep 1997||2 Feb 1999||Artifex, Ltd.||Dynamic intervertebral spacer and method of use|
|US5888220 *||23 Ene 1996||30 Mar 1999||Advanced Bio Surfaces, Inc.||Articulating joint repair|
|US6022376 *||16 Mar 1998||8 Feb 2000||Raymedica, Inc.||Percutaneous prosthetic spinal disc nucleus and method of manufacture|
|US6183518 *||23 Mar 1999||6 Feb 2001||Anthony C. Ross||Method of replacing nucleus pulposus and repairing the intervertebral disk|
|US6187043 *||21 Oct 1997||13 Feb 2001||Walter J. Ledergerber||Implantable prosthetic device|
|US6187048 *||23 May 1995||13 Feb 2001||Surgical Dynamics, Inc.||Intervertebral disc implant|
|US6190414 *||31 Oct 1996||20 Feb 2001||Surgical Dynamics Inc.||Apparatus for fusion of adjacent bone structures|
|US6193757 *||29 Oct 1998||27 Feb 2001||Sdgi Holdings, Inc.||Expandable intervertebral spacers|
|US6200320 *||18 Ago 1993||13 Mar 2001||Gary Karlin Michelson||Surgical rongeur|
|US6206930 *||10 Ago 1998||27 Mar 2001||Charlotte-Mecklenburg Hospital Authority||Absorbable tissue expander|
|US6358251 *||21 Mar 2000||19 Mar 2002||University Of Washington||Method and apparatus for forming a cavity in soft tissue or bone|
|US6508839 *||25 Oct 2000||21 Ene 2003||Intrinsic Orthopedics, Inc.||Devices and methods of vertebral disc augmentation|
|US6514256 *||15 Mar 2001||4 Feb 2003||St. Francis Medical Technologies, Inc.||Spine distraction implant and method|
|US6679886 *||28 Ago 2001||20 Ene 2004||Synthes (Usa)||Tools and methods for creating cavities in bone|
|US6695842 *||26 Oct 2001||24 Feb 2004||St. Francis Medical Technologies, Inc.||Interspinous process distraction system and method with positionable wing and method|
|US6699246 *||26 Abr 2001||2 Mar 2004||St. Francis Medical Technologies, Inc.||Spine distraction implant|
|US6699247 *||26 Abr 2001||2 Mar 2004||St. Francis Medical Technologies, Inc.||Spine distraction implant|
|US6709458 *||29 Ene 2001||23 Mar 2004||Gary Karlin Michelson||Expandable push-in arcuate interbody spinal fusion implant with tapered configuration during insertion|
|US6712819 *||18 Oct 2001||30 Mar 2004||St. Francis Medical Technologies, Inc.||Mating insertion instruments for spinal implants and methods of use|
|US6849092 *||8 Mar 2001||1 Feb 2005||Keraplast Technologies, Ltd.||Implantable prosthetic or tissue expanding device|
|US6852095 *||9 Jul 1998||8 Feb 2005||Charles D. Ray||Interbody device and method for treatment of osteoporotic vertebral collapse|
|US6869445 *||4 May 2000||22 Mar 2005||Phillips Plastics Corp.||Packable ceramic beads for bone repair|
|US6981981 *||29 Dic 2003||3 Ene 2006||Kyphon Inc.||Inflatable device for use in surgical protocol relating to fixation of bone|
|US6984247 *||12 Feb 2003||10 Ene 2006||Anulex Technologies, Inc.||Spinal disc annulus reconstruction method and spinal disc annulus stent|
|US6986788 *||9 Abr 2001||17 Ene 2006||Synthes (U.S.A.)||Intervertebral allograft spacer|
|US6997956 *||19 Mar 2003||14 Feb 2006||Anulex Technologies, Inc.||Spinal disc annulus reconstruction method and spinal disc annulus stent|
|US7001431 *||13 Feb 2003||21 Feb 2006||Disc Dynamics, Inc.||Intervertebral disc prosthesis|
|US7004970 *||24 Dic 2002||28 Feb 2006||Anulex Technologies, Inc.||Methods and devices for spinal disc annulus reconstruction and repair|
|US7008424 *||17 Oct 2003||7 Mar 2006||University Of Southern California||Percutaneous vertebral fusion system|
|US7008453 *||7 Jul 2000||7 Mar 2006||Sdgi Holdings, Inc.||Expandable push-in arcuate interbody spinal fusion implant with cylindrical configuration during insertion|
|US7014659 *||9 Dic 2003||21 Mar 2006||Synthes (Usa)||Skeletal reconstruction cages|
|US7156877 *||24 May 2002||2 Ene 2007||The Regents Of The University Of California||Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs|
|US7179262 *||4 Dic 2003||20 Feb 2007||Sdgi Holdings, Inc.||Method and apparatus for stereotactic implantation|
|US7189234 *||31 Oct 2001||13 Mar 2007||St. Francis Medical Technologies, Inc.||Interspinous process implant sizer and distractor with a split head and size indicator and method|
|US7189235 *||19 Mar 2003||13 Mar 2007||Anulex Technologies, Inc.||Spinal disc annulus reconstruction method and spinal disc annulus stent|
|US7318823 *||3 Jul 2003||15 Ene 2008||Arthrocare Corporation||Methods for repairing damaged intervertebral discs|
|US7331956 *||2 Ago 2006||19 Feb 2008||Arthrocare Corporation||Methods and apparatus for treating back pain|
|US7338526 *||7 Sep 2001||4 Mar 2008||Active Implants Corporation||Method and apparatus for computerized surgery|
|US7473268 *||2 Feb 2004||6 Ene 2009||Kyphon Sarl||Mating insertion instruments for spinal implants and methods of use|
|US7476226 *||18 Dic 2003||13 Ene 2009||Synthes (U.S.A.)||Tools and methods for creating cavities in bone|
|US7485119 *||14 Oct 2005||3 Feb 2009||Zimmer Technology, Inc.||Method and apparatus for reducing femoral fractures|
|US7488329 *||18 Feb 2005||10 Feb 2009||Zimmer Technology, Inc.||Method and apparatus for reducing femoral fractures|
|US7491219 *||3 Dic 2004||17 Feb 2009||Active Implants Corporation||Method and apparatus for computerized surgery|
|US7491236 *||22 Oct 2004||17 Feb 2009||Trans1, Inc.||Dual anchor prosthetic nucleus apparatus|
|US7497868 *||3 Dic 2004||3 Mar 2009||Active Implants Corporation||Method and apparatus for computerized surgery|
|US7503936 *||23 Sep 2004||17 Mar 2009||Warsaw Orthopedic, Inc.||Methods for forming and retaining intervertebral disc implants|
|US7507243 *||7 May 2003||24 Mar 2009||Gregory Lambrecht||Devices and method for augmenting a vertebral disc|
|US7510567 *||5 Abr 2004||31 Mar 2009||Kyphon Sarl||Spinal implants, insertion instruments, and methods of use|
|US7641658 *||25 Jun 2003||5 Ene 2010||Warsaw Orthopedic, Inc.||Transpedicular intervertebral disk access methods and devices|
|US7641692 *||8 Ago 2001||5 Ene 2010||Warsaw Orthopedic, Inc.||Implantable joint prosthesis|
|US7655042 *||30 Nov 2004||2 Feb 2010||Warsaw Orthopedic, Inc.||Expandable intervertebral spacers|
|US7658765 *||22 Oct 2004||9 Feb 2010||Intrinsic Therapeutics, Inc.||Resilient intervertebral disc implant|
|US7662173 *||22 Oct 2004||16 Feb 2010||Transl, Inc.||Spinal mobility preservation apparatus|
|US7670379 *||16 Feb 2006||2 Mar 2010||Anulex Technologies, Inc.||Spinal disc annulus reconstruction method|
|US7682364 *||2 Mar 2006||23 Mar 2010||Kyphon Sarl||Method for treating a bone|
|US20020022856 *||4 Jun 2001||21 Feb 2002||Wesley Johnson||Transverse cavity device and method|
|US20020026195 *||6 Abr 2001||28 Feb 2002||Kyphon Inc.||Insertion devices and method of use|
|US20020032447 *||28 Ago 2001||14 Mar 2002||Stuart Weikel||Tools and methods for creating cavities in bone|
|US20030033017 *||24 May 2002||13 Feb 2003||The Regents Of The University Of California||Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs|
|USRE40156 *||9 Oct 2003||18 Mar 2008||Arthrocare Corporation||Methods for repairing damaged intervertebral discs|
|Patente citante||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US7666226||15 Ago 2006||23 Feb 2010||Benvenue Medical, Inc.||Spinal tissue distraction devices|
|US7666227||15 Ago 2006||23 Feb 2010||Benvenue Medical, Inc.||Devices for limiting the movement of material introduced between layers of spinal tissue|
|US7670374||15 Ago 2006||2 Mar 2010||Benvenue Medical, Inc.||Methods of distracting tissue layers of the human spine|
|US7670375||15 Ago 2006||2 Mar 2010||Benvenue Medical, Inc.||Methods for limiting the movement of material introduced between layers of spinal tissue|
|US7785368||15 Ago 2006||31 Ago 2010||Benvenue Medical, Inc.||Spinal tissue distraction devices|
|US7879103||17 Abr 2006||1 Feb 2011||Musculoskeletal Transplant Foundation||Vertebral disc repair|
|US7909873||14 Dic 2007||22 Mar 2011||Soteira, Inc.||Delivery apparatus and methods for vertebrostenting|
|US7931689||19 Mar 2004||26 Abr 2011||Spineology Inc.||Method and apparatus for treating a vertebral body|
|US7955391||15 Feb 2010||7 Jun 2011||Benvenue Medical, Inc.||Methods for limiting the movement of material introduced between layers of spinal tissue|
|US7959638||25 Mar 2003||14 Jun 2011||Kyphon Sarl||Methods and devices for treating bone after high velocity and/or trauma fracture|
|US7959683||23 Jul 2007||14 Jun 2011||Musculoskeletal Transplant Foundation||Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation|
|US7963993||15 Feb 2010||21 Jun 2011||Benvenue Medical, Inc.||Methods of distracting tissue layers of the human spine|
|US7967864||15 Feb 2010||28 Jun 2011||Benvenue Medical, Inc.||Spinal tissue distraction devices|
|US7967865||15 Feb 2010||28 Jun 2011||Benvenue Medical, Inc.||Devices for limiting the movement of material introduced between layers of spinal tissue|
|US7988735 *||16 Dic 2008||2 Ago 2011||Matthew Yurek||Mechanical apparatus and method for delivering materials into the inter-vertebral body space for nucleus replacement|
|US8021365||30 Mar 2007||20 Sep 2011||Kyphon Sarl||Surgical device having interchangeable components and methods of use|
|US8021366||30 Mar 2007||20 Sep 2011||Kyphon Sarl||Axial load limiting system and methods|
|US8057544||15 Ago 2006||15 Nov 2011||Benvenue Medical, Inc.||Methods of distracting tissue layers of the human spine|
|US8100973||30 Sep 2008||24 Ene 2012||Soteira, Inc.||Cement-directing orthopedic implants|
|US8105236||7 Jun 2006||31 Ene 2012||Kyphon Sarl||Surgical access device, system, and methods of use|
|US8226719 *||14 Nov 2007||24 Jul 2012||Cook Medical Technologies Llc||Method and bone cement substitute kit for stabilizing a collapsed vertebra of a patient|
|US8317791||30 Mar 2007||27 Nov 2012||Kyphon Sarl||Torque limiting device and methods|
|US8366773||25 Ene 2008||5 Feb 2013||Benvenue Medical, Inc.||Apparatus and method for treating bone|
|US8409211||7 Oct 2008||2 Abr 2013||Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Et Genie S.E.C.||Integrated cement delivery system for bone augmentation procedures and methods|
|US8454617||4 Jun 2013||Benvenue Medical, Inc.||Devices for treating the spine|
|US8518115||13 Nov 2008||27 Ago 2013||DePuy Synthes Products, LLC||Porous containment device and associated method for stabilization of vertebral compression fractures|
|US8535327||16 Mar 2010||17 Sep 2013||Benvenue Medical, Inc.||Delivery apparatus for use with implantable medical devices|
|US8540752||27 Jun 2008||24 Sep 2013||Spine Tek, Inc.||Interspinous mesh|
|US8556978||15 Nov 2011||15 Oct 2013||Benvenue Medical, Inc.||Devices and methods for treating the vertebral body|
|US8591583||21 Feb 2008||26 Nov 2013||Benvenue Medical, Inc.||Devices for treating the spine|
|US8623025||15 Ene 2010||7 Ene 2014||Gmedelaware 2 Llc||Delivery apparatus and methods for vertebrostenting|
|US8801787||16 Jun 2011||12 Ago 2014||Benvenue Medical, Inc.||Methods of distracting tissue layers of the human spine|
|US8808376||25 Mar 2009||19 Ago 2014||Benvenue Medical, Inc.||Intravertebral implants|
|US8814873||22 Jun 2012||26 Ago 2014||Benvenue Medical, Inc.||Devices and methods for treating bone tissue|
|US8882836||18 Dic 2012||11 Nov 2014||Benvenue Medical, Inc.||Apparatus and method for treating bone|
|US8906022||8 Mar 2011||9 Dic 2014||Conventus Orthopaedics, Inc.||Apparatus and methods for securing a bone implant|
|US8911497||6 Abr 2010||16 Dic 2014||DePuy Synthes Products, LLC||Minimally invasive spine augmentation and stabilization system and method|
|US8945224 *||18 Mar 2010||3 Feb 2015||Warsaw, Orthopedic, Inc.||Sacro-iliac implant system, method and apparatus|
|US8961518||19 Ene 2011||24 Feb 2015||Conventus Orthopaedics, Inc.||Apparatus and methods for bone access and cavity preparation|
|US8961609||26 Sep 2013||24 Feb 2015||Benvenue Medical, Inc.||Devices for distracting tissue layers of the human spine|
|US8979929||16 Jun 2011||17 Mar 2015||Benvenue Medical, Inc.||Spinal tissue distraction devices|
|US8986386||12 Mar 2009||24 Mar 2015||Vexim Sas||Apparatus for bone restoration of the spine and methods of use|
|US9114019||29 Jul 2013||25 Ago 2015||DePuy Synthes Products, Inc.||Porous containment device and associated method for stabilization of vertebral compression fractures|
|US20050131417 *||23 Ago 2004||16 Jun 2005||Ahern James W.||Kit for treating bony defects|
|US20050261781 *||14 Abr 2005||24 Nov 2005||Sennett Andrew R||Cement-directing orthopedic implants|
|US20070006692 *||21 Oct 2005||11 Ene 2007||Phan Christopher U||Torque limiting device|
|US20070010716 *||7 Jun 2006||11 Ene 2007||Malandain Hugues F||Surgical access device, system, and methods of use|
|US20070010824 *||24 Abr 2006||11 Ene 2007||Hugues Malandain||Products, systems and methods for delivering material to bone and other internal body parts|
|US20070010844 *||8 Jul 2005||11 Ene 2007||Gorman Gong||Radiopaque expandable body and methods|
|US20070010845 *||8 Jul 2005||11 Ene 2007||Gorman Gong||Directionally controlled expandable device and methods for use|
|US20070093899 *||25 Sep 2006||26 Abr 2007||Christof Dutoit||Apparatus and methods for treating bone|
|US20090104586 *||23 Oct 2008||23 Abr 2009||Osseous Technologies Of America||Collagen Antral Membrane Expander|
|US20090125031 *||14 Nov 2007||14 May 2009||Cook Incorporated||Method and bone cement substitute kit for stabilizing a collapsed vertebra of a patient|
|US20090281628 *||2 Abr 2009||12 Nov 2009||Jean-Francois Oglaza||Apparatus for restoration of the spine and methods of use thereof|
|US20110184520 *||27 Ene 2010||28 Jul 2011||Warsaw Orthopedic, Inc.||Sacro-iliac joint implant, method and apparatus|
|US20110230966 *||18 Mar 2010||22 Sep 2011||Warsaw Orthopedic, Inc.||Sacro-iliac implant system, method and apparatus|
|EP2724680A1||17 Oct 2013||30 Abr 2014||Spirit Spine Holdings Corporation, Inc.||Device for bone fixation|
|EP2921142A1||25 Jul 2014||23 Sep 2015||Spirit Spine Holdings Corporation, Inc.||Device for bone fixation|
|WO2008121608A2 *||25 Mar 2008||9 Oct 2008||Arthur E Ferdinand||Apparatuses and methods for bone screw augmentation|
|Clasificación de EE.UU.||623/17.12|
|Clasificación internacional||A61F2/00, A61B17/32, A61F2/46, A61B17/00, A61B17/34, A61B17/88, A61B17/68, A61F2/28, A61F2/44, A61B17/70, A61F2/30, A61F2/34|
|Clasificación cooperativa||A61F2002/30451, A61F2002/448, A61B17/00234, A61F2002/2828, A61F2/461, A61F2002/30581, A61B2017/00557, A61F2/0095, A61F2310/00353, A61F2230/0082, A61B17/7098, A61F2002/4602, A61F2002/30034, A61F2/441, A61B17/3472, A61B17/742, A61F2/34, A61F2/4601, A61B17/1671, A61F2002/4636, A61F2002/30271, A61B17/8855, A61F2250/0031, A61F2220/005, A61F2/4611, A61B17/68, A61F2002/2817, A61F2002/30718, A61F2002/2835, A61F2/4607, A61B17/8805, A61F2/44, A61F2310/00293, A61F2002/30069, A61B2017/00004, A61F2002/4635, A61F2230/0071, A61F2002/2832, A61F2002/3025, A61B2017/00261, A61B17/32002, A61F2220/0058, A61B17/1675, A61B17/1617, A61F2002/30448, A61F2002/2892, A61B17/1668|
|Clasificación europea||A61B17/70V2, A61B17/88C2B, A61B17/74D, A61B17/68|
|20 Mar 2006||AS||Assignment|
Owner name: SPINEOLOGY, MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:KUSLICH, STEPHEN D;REEL/FRAME:017333/0055
Effective date: 20060309
|30 Nov 2006||AS||Assignment|
Owner name: MUSCULOSKELETAL TRANSPLANT FOUNDATION, INC., NEW J
Free format text: SECURITY AGREEMENT;ASSIGNOR:SPINEOLOGY, INC.;REEL/FRAME:018563/0350
Effective date: 20061130
|5 Mar 2012||AS||Assignment|
Owner name: SPINEOLOGY, INC., MINNESOTA
Free format text: RELEASE BY SECURED PARTY;ASSIGNOR:MUSCULOSKELETAL TRANSPLANT FOUNDATION, INC.;REEL/FRAME:027805/0445
Effective date: 20120131