|Número de publicación||US20060253142 A1|
|Tipo de publicación||Solicitud|
|Número de solicitud||US 11/327,348|
|Fecha de publicación||9 Nov 2006|
|Fecha de presentación||9 Ene 2006|
|Fecha de prioridad||4 May 2005|
|También publicado como||US7674271, WO2007067641A2, WO2007067641A3|
|Número de publicación||11327348, 327348, US 2006/0253142 A1, US 2006/253142 A1, US 20060253142 A1, US 20060253142A1, US 2006253142 A1, US 2006253142A1, US-A1-20060253142, US-A1-2006253142, US2006/0253142A1, US2006/253142A1, US20060253142 A1, US20060253142A1, US2006253142 A1, US2006253142A1|
|Cesionario original||Bernard Medical, Llc|
|Exportar cita||BiBTeX, EndNote, RefMan|
|Citas de patentes (24), Citada por (51), Clasificaciones (17), Eventos legales (8)|
|Enlaces externos: USPTO, Cesión de USPTO, Espacenet|
This application claims priority to Provisional Patent Application No. 60,677,345, filed May 4, 2005; Provisional Patent Application No. 60/677,355, filed May 11, 2005; Provisional Patent Application No. 60/697,544, filed Jul. 11, 2005; Provisional Patent Application No. 60/698,941, filed Jul. 14, 2005; Non-provisional patent application Ser. No. 11/267321, filed Nov. 7, 2005; Non-provisional patent application Ser. No. 11/267266, filed Nov. 7, 2005; and Provisional Patent Application No. 60/748,148, filed Dec. 8, 2005, which are each are hereby incorporated by reference.
1. Field of the Invention
This invention relates in general to an endoluminal surgical procedure for the treatment and control of obesity and, more particularly, to gastric rings and a novel method for the endoluminal implantation of the rings.
2. Discussion of the Related Art
Methods used in the prior art to treat obesity include gastric bypass and small bowel bypass surgery. Stapling of portions of the stomach has also been used to treat morbid obesity. This includes both vertical and horizontal stapling and other variations which will reduce the size of the stomach and make a small stoma opening. Many problems have been associated with the use of staples. First, staples are undependable. Second, staples may cause perforations in the stomach wall. Finally, the pouch or the stoma formed by the staples may become enlarged over time, thereby making the procedure useless.
A promising method for weight control employs the placement of a band around a portion of the stomach by open or laparoscopic surgery, thereby compressing the stomach and creating a stoma that is less than the normal interior diameter of the stomach. The constricted stoma restricts food intake into the lower digestive portion of the stomach. Such a band has been described by Kuzmak et al in U.S. Pat. Nos. 4,592,339, 5,074,868, and 5,226,429, which are hereby incorporated by reference.
These devices, known as gastric bands, require a surgical procedure for their implantation, which includes accessing the patient's stomach and other internal organs via incisions. The invasiveness related to these surgical procedures can cause pain, prolonged recovery, complications, and great expense to the patient and to the healthcare system. Moreover, the procedure can also be technically challenging for the surgeon.
Suturing devices described by Bjerken in U.S. Pat. No. 6,464,707 and in U.S. patent application Ser. No. 11/267266 enable an operator to remotely place suture material within a closed space such a hollow body organ. Such devices enable the endoluminal implantation of prostheses, correction of defects, and the reconfiguration of tissue without the need for surgical incisions. U.S. Pat. No. 6,464,707 and U.S. patent application Ser. No. 11/267266 are hereby incorporated by reference in their entirety.
The present invention includes prostheses, such as a ring, or series of rings; a suturing device; and a method for suturing prostheses within a subject. The rings are adapted to hold tissue in place around their circumference to create a constriction within an organ. If the organ is a stomach, the constriction is positioned such that a pouch of a certain volume is created proximal to the constriction, leaving a narrow passage to the remainder of the stomach's volume distal to the constriction. The suturing device is adapted to be passed into a patient's digestive system via a natural orifice, such as the mouth or anus. The suturing device can be adapted to expand once inside an organ and place multiple sutures in tissue around the circumference of the suturing device. After deploying suture, the device can be adapted to collapse to its original size to enable the withdrawal of the device. The rings are adapted to be held in place within an organ by the sutures.
The invention may take form in certain components and structures, preferred embodiments of which are illustrated in the accompanying drawings.
The present invention is more particularly described in the following examples with reference to the accompanying drawings that are intended as illustrative only since numerous modifications and variations therein will be apparent to those skilled in the art.
For the placement of gastric rings or other implants within a patient shown in the exemplary embodiment of
In one embodiment, the tube 1 has a length sufficient to span the distance from its place of insertion to the targeted surgical location. For example, in gastrointestinal (GI) uses, the tube 1 can be approximately 2 to 3 feet. The length of the tube 1 for this embodiment should enable the device to reach several organs within the GI tract or within the abdominal cavity while a proximal end of the tube remains outside the patient's body and accessible to the operator.
The tube 1 can be circular in its cross-section or it may have a non-circular cross-section. Possible cross-sectional shapes are oval, rectangular, or irregular, such as the shape of a mitral valve annulus.
The tube 1 can house an endoscope (not shown). The device may include and be connected to the endoscope, or the endoscope may work in concert with the device. The device may also work without an endoscope.
Generally, an operator manipulates the tube 1 to place the device at a desired location. The endoscope contained within the flexible tube 1 of the device may assist in directing the device to the desired location by applying force to the wall of the tube 1, to steer the device. Alternatively, the tube 1 may have the ability to direct or steer itself by using various methods of steering. For example, a balloon catheter (not shown) can run parallel within or along a side of the tube 1. The catheter (not shown) may be endoscopically placed in a defect, annulus, valve, or outlet, and inflated to hold the device in place. The tube 1 can then be slid down the catheter (not shown) to be positioned and maintained in the desired location. In vascular applications, the device can be directed in a similar fashion following a guide wire (not shown). The tube 1 can incorporate radio opaque markers (not shown) to enable visualization using fluoroscopy. In yet another embodiment, wires or cables can be used by varying tensions to turn the device within the closed organ or space. Steering the device may not be necessary for the implantation of gastric rings within the stomach.
The tube 1 can be in fluid communication with a vacuum source and can include or define one or more suction ports 5. The port 5 is generally located near the distal end of the tube 1, although other locations are possible. The suction port 5 can completely or partially circumscribe a portion of the distal end of the tube 1. In one embodiment, the device has a series of suction ports spaced around its circumference. Generally, the area immediately distal and proximal to, and including, the suction port 5 is designed to expand and contract in diameter as shown in
One or more cannulas 2, 3 are arranged within the tube 1. In the illustrated embodiment, for example, in
Generally, a cannula is a tubular passageway though which material can travel in either a forward or backward direction. Each cannula has an internal diameter adequate to contain one or more needles and accompanying sutures.
The cannulas 2, 3 are utilized to direct needles 20 to an intended point of incorporation with tissue. The cannulas 2, 3 maintain the movement of the needles in a forward or backward direction and contain or prohibit lateral movement and bending of the needles. Although the cannulas 2, 3 are referred to as “delivery” and “receiving cannulas herein, either set of cannulas can deliver or receive the needles. The delivery cannulas 2 loop at cannula loop 4 and extend up through the central portion of device via a central delivery cannula shaft 11. The central delivery cannula shaft 11 can be a single shaft through which the needles 20 extend, or a collection or bundle of individual cannulas. The receiving cannulas 3 can be bundled or formed together in a similar fashion proximal to the expandable area of the tube 1. The needles 20 can be manipulated via the portions of the needles extending out of the proximal end of the device, as shown in
The cannulas 2, 3 can be formed, molded, and/or cast as part of the tube 1, or can be independent components inserted into the tube 1. The cannulas 2, 3 can be flexible, but may optionally have rigid sections as necessary to allow turning and targeting of the needles 20. The cannulas 2, 3 may be made of extruded plastic tubing reinforced with braided stainless wire.
The cannulas 2, 3 can be configured within the tube in many ways. The cannulas 2, 3 may have flared or trumpet shaped openings (not shown) to assist in receiving the needles 20 once they have traversed the suction port 5.
The needles 20 completely traverse the tissue drawn within the suction port and may enter the receiving cannulas 3 at or near the upper side of the suction port 5. This creates a “bite” or suture of tissue.
The suturing device of the present invention generally utilizes long suture needles 20 made of a material that has the properties of shape memory, such as Nitinol. Nitinol is a nickel and titanium alloy that quickly returns to an original configuration after being flexed. Other materials can also be used, such as stainless steel. In one embodiment, the suture needles 20 can be of adequate length to reach a suturing site, via a natural body orifice such as the mouth or anus, or an incision or stoma, and return back out of the device. As such, the needles 20 are typically at least twice the length of the tube 1 of the device. As an example, a needle utilized for gastrointestinal applications can be approximately 6 feet long. The needles 20 can be attached to suture material to deliver and incorporate suture material 7 into tissue that the needles 20 traverse.
In one embodiment of the present invention, the needles are straight. The needles have a flexibility to follow the path within a cannula, 2, 3, which may include various turns and loops, without losing its original shape. The generally straight shape of the needles 20 allows them to exit the cannulas, 2, 3 transect a port or ports in the tube such as a suction port 5, and proceed in the direction in which it has been directed.
The needles 20 can be longer or shorter depending on the desired application, such as cardiac, vascular, gynecological, proctological, pulmonary, and general surgical procedures, or depending on the embodiment of the present invention. The needles 20 may have a distal tip or end that is made of a material that is more rigid, such as steel or titanium. The needles 20 may have differing diameter or gauge depending upon the application. By way of example, vascular anastomosis generally requires relatively thin needles, for example, needles with a diameter of about 0.1 mm to about 0.5 mm. The needles 20 may also have an original configuration other than straight, such as having a bend, curve or coil.
In some embodiments, the suturing device does not use a vacuum source. The tube 1 may be of a size such that the tissue envelops or enters into a port 5 without the need of a vacuum. This embodiment can be useful, for example, in a tissue-to-tissue anastomosis or tissue defect closure application.
The circumferential suction port 5 illustrated in
Alternatively, the curvature or inward concavity of the strut may be formed by two or more straight members with a hinge in the middle, so that when the hinge is pulled inward a V shape is formed. Also alternatively, as illustrated in
The circumferential suction opening 5 for a circumferential placement of suture enables anastomosis, connection of tissue to tissue, or connection of tissue to a prosthetic graft. Particularly, the circumferential suction port enables the placement of a gastric ring or rings. In the embodiment shown in
In another exemplary embodiment, a flexible plastic, non-porous fabric, or cellophane material 8 forms the expandable area of the tube 1. The distal end of the cannulas can be straight and made of a material such as metal or plastic. As shown in
In an alternative embodiments of the suturing device, illustrated in
In the embodiment shown in
In another embodiment illustrated in
In each of the embodiments, the distal ends of the delivery cannulas 2, or alternatively, the relatively short cannula segments 43, may be spaced around the circumference of the suction port 5 in a variety of fashions. In an exemplary embodiment, the delivery cannulas 2 are spaced about the circumference of the suction port 5 such that they are spaced as pairs of cannulas. Each pair of cannula can contain the two suture needles 20, 46, 48 connected by the one suture length 7. The pair can be spaced approximately 1 cm apart from one another at their distal ends when the expandable area of the device is fully expanded. If the double-armed suture is back-loaded into each cannula pair, the loop of suture that bridges the two cannulas is incorporated with the intended distal prosthesis as described later.
The shape of the expandable area of the suturing device may be capsule, spherical, or football shaped with the cannulas 2, 3 distributed equidistant from the central shaft 11. Alternatively, the expandable area of the tube 1 may have an irregular shape that can be adapted to conform to the natural shape of the interior of the organ. The suction opening 5 may also be irregular or non-circular in circumference. The proximal section of the expandable area may have the approximate same surface area of interior of the created proximal organ pouch. In other words, the device can be useful to template the resulting gastric pouch.
The implantable gastric rings 6, 12 are used to hold or secure portions of the stomach wall around their circumference. Ring 6 is shown in
In the exemplary embodiment where two gastric rings 6,12 are employed, once implanted, the result is two rings 6, 12 held together with tissue sandwiched between them, as illustrated in
The tissue 15 held between the rings may protrude within the circumference of the rings, 6 12. This produces a small outlet 14 made up of the tissue 15 of the organ. The size of the resulting outlet 14 can be measured and altered as necessary for the particular patient at the time of implantation by varying the amount of tension between the rings and or by selecting a larger or smaller proximal gastric ring 12.
The rings 6, 12 are configured in a generally circular shape, although other configurations are possible, for example, an oval shape. The ring 6, 12 may contain holes or slots 27 through which suture can be passed. In another embodiment, the ring initially has no holes and the suture needles pierce the ring material 28 and are passed through. The rings 6, 12 can be made of a flexible material that can be temporarily held in any shape. Flexible rings 6, 12 can be made of biocompatible material such as plastic, silicone, polypropylene, Nitinol, stainless steel cable, Gortex, Nylon, Teflon, fabric, rubber, composites of material, or another like material that bends but does not necessarily stretch or have elastic properties.
The suturing device can be loaded with the double-armed sutures and the distal gastric ring 6 in the following manner. As illustrated in
As illustrated in
The flexible ring 6 may be a linear length of material that is implanted in a circular fashion, as illustrated in FIGS. 12A and 14-15A. The length of material can be incorporated with sutures and releasably held on the distal end of the suturing device, as shown in
In use, the suturing device deploys the incorporated sutures about the circumference of the lumen of an organ such as the stomach with unsecured mattress suture bites. A secured mattress suture bite can be provided wherein the two arms of a suture enter the first side of an object and/or tissue, exit a second side of an object and/or tissue and are secured together, forming a closed circuit of suture material. The flexible length of material is now held by the sutures distal to the tissue incorporated with the sutures. The second or proximal ring may now be incorporated with the sutures and lowered into the stomach and positioned above the length of material. The second proximal ring may be formed as a ring or it may be a length of material similar to the distal ring. If the proximal ring is a linear length of material, it can be incorporated with the sutures and aligned such that, when formed as a circle, the break in the circumference 19 formed by the two endpoints of the length of material are not be aligned with the break in the circumference of the distal ring. In an exemplary embodiment, the breaks 19 in the circumference should be 180 degrees apposed, as illustrated in
Rigid gastric rings with a diameter that is amenable to be passed trans-orally or trans-anally (10 mm-33 mm) can be formed as a closed circle. In another embodiment, as illustrated in
The rings 6, 12 can have any cross-section, for example, flat, round, oval, or irregular. The rings 6, 12 can have a diameter of 10 mm to 50 mm for gastric reduction, but rings can also have a diameter from 3 mm to 150 mm.
Closed rigid rings 6, 12 could be made of plastic, stainless steel, Nitinol, titanium, carbon fiber, or another like material which is compatible with biologic tissue.
The suture can be made of any material, for example, a non-absorbable material such as polypropylene. The size of the diameter of the suture may vary, although a 3.0 or 2.0 size suture can be particularly useful. The length of the suture connecting the two suture needles needs to be of adequate length to span the length of the two suture needles, plus the slack needed to loop through the gastric ring or other prosthesis. For example, if the length of the needles 20 utilized is six feet, then the suture 7 connecting them would need to be approximately thirteen feet.
To implant the gastric rings 6, 12, the device, loaded with the distal gastric ring 6, is inserted in its collapsed configuration, as shown in
Because the implantation of the rings 6, 12 involves multiple needles 20 and attached suture 7 arms, the needles and suture arms should be maintained in their proper configuration or order throughout the implantation procedure. Procedures and devices may be used to maintain suture arm order. Clamps can be used to grasp each suture arm and then maintain the order of the clamps until the proximal prosthesis is incorporated. Alternatively, a mechanism that has the ability to releasably hold needles or suture arms about its circumference may be used, as illustrated in
As illustrated in
If necessary, the gastric ring implantation procedure can be easily reversed by simply cutting the sutures connecting the rings while using endoscopic instrumentation, and removing the rings.
The distal or proximal gastric ring can be replaced with an alternate prosthesis such as a valve, stent, or graft utilizing the present invention. One-way valves utilizing leaflets or floppy tubes can be used in the gastrointestinal tract to prevent backflow of contents such as with gastroesophageal reflux disease (GERD). Expandable stents can be utilized to maintain a level of patency within a lumen. The suturing device of the present invention enables a stent to be secured at a location within the lumen, thereby prohibiting migration or movement of the stent after its endoluminal placement. The suture loops, which pass through the prostheses, can incorporate material that secure themselves and eliminate the need for tying. Self-tying U-clips made of a shape memory material is one example.
In one embodiment, the gastric ring can be described as a series of pledgets 28 connected to one another by a length of material 29 in the form of a circle, providing hoop strength to the tissue folds drawn into its circumference. In one embodiment, the material making up the pledget portions of the ring may be made of a material with different properties from the material making up the remainder of the ring's circumference. The pledget 28 function of the ring maintains the ring-to-tissue-to-ring configuration and connection while it prevents or retards the suture from tearing through the tissue. The ring, or closed circuit, function of the ring holds and maintains the incorporated tissue in a circumferential fashion as illustrated in
In one embodiment, as an alternative to the expandable umbrella struts, the expandable area of the device could expand by means of an inflatable member such as a balloon or balloons. The balloon or balloons, when inflated, would force the cannula outward to a preset diameter. Flexible strings or wires connecting the concave suction port struts to the central shaft can enable a predetermined radius size of the expanded area.
As illustrated in
As illustrated in
The expandable portions of the device tube proximal and distal to the suction opening 5 may expand and collapse in concert with one another, or alternatively, they may expand and collapse independently from one another.
The suture 7 on the distal ring 6 may not loop through the material, but may in fact be connected to, or formed together with, the distal ring such that each suture arm connects to the ring directly.
As illustrated in
The ring material of the rings 6 and 12 may be made of, contain, or coated with a biodegradable substance, such as a drug, that eludes a steady dose of the drug over time. This substance could be an appetite suppressant, a proton pump inhibitor, an anti-inflammatory drug, or other medication. For example, the drug can be an appetite suppressant that is eluded for a discrete amount of time to assist a patient in assimilating to their new eating pattern.
Plastic, rubber or cellophane sheaths may be used to cover the proximal ends of the needles 20 and attached sutures 7 prior to their deployment. The sheaths help maintain sterility of the needles 20 and suture 7 and will reduce the possibility of the suture loops 7 from becoming entangled with each other prior to, and as the needles 20 are being deployed.
|Patente citada||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US4957499 *||27 Jun 1988||18 Sep 1990||Lipatov Viktor A||Surgical suturing instrument|
|US5330503 *||13 Ago 1992||19 Jul 1994||Inbae Yoon||Spiral suture needle for joining tissue|
|US5792152 *||26 Abr 1996||11 Ago 1998||Perclose, Inc.||Device and method for suturing of internal puncture sites|
|US5891155 *||18 Sep 1997||6 Abr 1999||Scimed Life Systems, Inc.||Embolizing system|
|US6048351 *||10 Abr 1998||11 Abr 2000||Scimed Life Systems, Inc.||Transvaginal suturing system|
|US6464701 *||29 Sep 2000||15 Oct 2002||Enable Medical Corporation||Bipolar electrosurgical scissors|
|US6464707 *||31 Mar 2000||15 Oct 2002||David B. Bjerken||Vacuum-assisted remote suture placement system|
|US6558400 *||30 May 2001||6 May 2003||Satiety, Inc.||Obesity treatment tools and methods|
|US6572629 *||15 Ago 2001||3 Jun 2003||Johns Hopkins University||Gastric reduction endoscopy|
|US6675809 *||27 Ago 2001||13 Ene 2004||Richard S. Stack||Satiation devices and methods|
|US6769590 *||2 Abr 2002||3 Ago 2004||Susan E. Vresh||Luminal anastomotic device and method|
|US6773440 *||2 Jul 2002||10 Ago 2004||Satiety, Inc.||Method and device for use in tissue approximation and fixation|
|US6845776 *||8 Abr 2002||25 Ene 2005||Richard S. Stack||Satiation devices and methods|
|US6997931 *||2 Feb 2001||14 Feb 2006||Lsi Solutions, Inc.||System for endoscopic suturing|
|US7111627 *||9 Jun 2003||26 Sep 2006||Synecor, Llc||Satiation devices and methods|
|US7121283 *||4 Mar 2004||17 Oct 2006||Synecor, Llc||Satiation devices and methods|
|US7141055 *||24 Abr 2003||28 Nov 2006||Surgical Connections, Inc.||Resection and anastomosis devices and methods|
|US7152607 *||4 Mar 2004||26 Dic 2006||Synecor, L.L.C.||Satiation devices and methods|
|US7371251 *||2 Jun 2005||13 May 2008||Cordis Neurovascular, Inc.||Stretch resistant embolic coil delivery system with mechanical release mechanism|
|US20020072761 *||24 Ago 2001||13 Jun 2002||Surgical Connections, Inc.||Surgical stabilizer devices and methods|
|US20040082963 *||23 Oct 2002||29 Abr 2004||Jamy Gannoe||Method and device for use in endoscopic organ procedures|
|US20040181238 *||14 Mar 2003||16 Sep 2004||David Zarbatany||Mitral valve repair system and method for use|
|US20050038468 *||2 Jul 2004||17 Feb 2005||Regents Of The University Of Minnesota||Medical device and method of intravenous filtration|
|US20060025802 *||25 Jul 2005||2 Feb 2006||Sowers William W||Embolic coil delivery system with U-shaped fiber release mechanism|
|Patente citante||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US7708181||21 Mar 2008||4 May 2010||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7721932||21 Mar 2008||25 May 2010||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7883524||21 Dic 2007||8 Feb 2011||Wilson-Cook Medical Inc.||Method of delivering an intragastric device for treating obesity|
|US7892292||30 Jun 2006||22 Feb 2011||Synecor, Llc||Positioning tools and methods for implanting medical devices|
|US7909219||21 Mar 2008||22 Mar 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7909222||21 Mar 2008||22 Mar 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7909223||21 Mar 2008||22 Mar 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7913892||21 Mar 2008||29 Mar 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7922062||21 Mar 2008||12 Abr 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US7934631||10 Nov 2008||3 May 2011||Barosense, Inc.||Multi-fire stapling systems and methods for delivering arrays of staples|
|US7967818||8 Jun 2006||28 Jun 2011||Cook Medical Technologies Llc||Cautery catheter|
|US8007507||10 May 2007||30 Ago 2011||Cook Medical Technologies Llc||Intragastric bag apparatus and method of delivery for treating obesity|
|US8016851||27 Dic 2007||13 Sep 2011||Cook Medical Technologies Llc||Delivery system and method of delivery for treating obesity|
|US8020741||18 Mar 2008||20 Sep 2011||Barosense, Inc.||Endoscopic stapling devices and methods|
|US8029455||5 Mar 2009||4 Oct 2011||Barosense, Inc.||Satiation pouches and methods of use|
|US8083758 *||10 Oct 2007||27 Dic 2011||Hourglass Technologies, Inc.||Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue|
|US8100925||5 Nov 2008||24 Ene 2012||Hourglass Technologies, Inc.||Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue|
|US8109895||31 Ago 2007||7 Feb 2012||Barosense, Inc.||Intestinal sleeves and associated deployment systems and methods|
|US8206456||23 May 2006||26 Jun 2012||Barosense, Inc.||Restrictive and/or obstructive implant system for inducing weight loss|
|US8216268||21 Dic 2006||10 Jul 2012||Cook Medical Technologies Llc||Intragastric bag for treating obesity|
|US8226668||1 May 2008||24 Jul 2012||Ethicon Endo-Surgery, Inc.||Tissue apposition method and device involving sheets with integrated tensioning system|
|US8241202||22 Abr 2010||14 Ago 2012||Barosense, Inc.||Restrictive and/or obstructive implant for inducing weight loss|
|US8257374 *||5 Nov 2008||4 Sep 2012||Hourglass Technologies, Inc.||Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue|
|US8337566||4 Dic 2009||25 Dic 2012||Barosense, Inc.||Method and apparatus for modifying the exit orifice of a satiation pouch|
|US8372088 *||14 Sep 2011||12 Feb 2013||Hesham Morsi||Suturing device for anastomisis of lumens|
|US8435203 *||20 Jun 2007||7 May 2013||Covidien Lp||Gastric restrictor assembly and method of use|
|US8469977||21 May 2010||25 Jun 2013||Barosense, Inc.||Endoscopic plication device and method|
|US8568488||1 Oct 2009||29 Oct 2013||Boston Scientific Scimed, Inc.||Satiation devices and methods|
|US8591533||6 Feb 2008||26 Nov 2013||The Ohio State University Research Foundation||Endolumenal restriction method and apparatus|
|US8747421||18 Abr 2011||10 Jun 2014||Boston Scientific Scimed, Inc.||Multi-fire stapling systems and methods for delivering arrays of staples|
|US8784354 *||22 Feb 2011||22 Jul 2014||Boston Scientific Scimed, Inc.||Positioning tools and methods for implanting medical devices|
|US8784500||8 Oct 2004||22 Jul 2014||Boston Scientific Scimed, Inc.||Devices and methods for retaining a gastro-esophageal implant|
|US8845753||30 Sep 2013||30 Sep 2014||Boston Scientific Scimed, Inc.||Satiation devices and methods|
|US8864008||21 Mar 2011||21 Oct 2014||Boston Scientific Scimed, Inc.||Endoscopic stapling devices and methods|
|US8945167||1 Sep 2011||3 Feb 2015||Boston Scientific Scimed, Inc.||Gastric space occupier systems and methods of use|
|US8961539||4 May 2009||24 Feb 2015||Boston Scientific Scimed, Inc.||Endoscopic implant system and method|
|US8992457||14 Jul 2011||31 Mar 2015||Boston Scientific Scimed, Inc.||Gastrointestinal implants|
|US9107727||22 Ene 2014||18 Ago 2015||Boston Scientific Scimed, Inc.||Satiation devices and methods|
|US9138340||25 Ago 2014||22 Sep 2015||Boston Scientific Scimed, Inc.||Gastro-esophageal implants|
|US20050247320 *||11 May 2004||10 Nov 2005||Stack Richard S||Devices and methods for retaining a gastro-esophageal implant|
|US20080319470 *||20 Jun 2007||25 Dic 2008||Viola Frank J||Gastric restrictor assembly and method of use|
|US20110153030 *||23 Jun 2011||Synecor, Llc||Positioning tools and methods for implanting medical devices|
|US20110245854 *||6 Oct 2011||Hourglass Technologies, Inc.||Devices and methods to deliver, retain and remove a separating device in an intussuscepted hollow organ|
|US20120004590 *||5 Ene 2012||Barosense, Inc||Satiation pouches and methods of use|
|US20120004670 *||5 Ene 2012||Hesham Morsi||Suturing Device for Anastomisis of Lumens|
|US20120296354 *||2 Ago 2012||22 Nov 2012||Hsu Charles S||Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue|
|US20130123811 *||16 May 2013||Bfkw, Llc||Medical device fixation tool and method of fixation of a medical device|
|US20130218174 *||24 Ago 2011||22 Ago 2013||Intailor Surgical, Llc||Suturing devices, systems and methods of using the same|
|EP2104458A2 *||8 Ene 2008||30 Sep 2009||Endogastric Solutions||Connected fasteners, delivery device and method|
|WO2008117276A1 *||19 Mar 2008||2 Oct 2008||Keren Medical Ltd||Anastomosis suturing device and methods thereof|
|WO2009135002A1 *||30 Abr 2009||5 Nov 2009||Ethicon Endo-Surgery, Inc.||Tissue apposition method and device involving sheets with integrated tensioning system|
|Clasificación de EE.UU.||606/153|
|Clasificación cooperativa||A61B2017/0472, A61B17/1114, A61B17/00234, A61B2017/047, A61B2017/0406, A61B2017/0496, A61B17/0482, A61B17/0469, A61B2017/1139, A61B2017/06057, A61B2017/1103, A61B17/0401, A61B2017/00827|
|Clasificación europea||A61B17/04G, A61B17/00E|
|9 Ene 2006||AS||Assignment|
Owner name: BERNARD MEDICAL, LLC,GEORGIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BJERKEN, DAVID;REEL/FRAME:017438/0291
Effective date: 20060109
|18 Oct 2013||REMI||Maintenance fee reminder mailed|
|9 Mar 2014||LAPS||Lapse for failure to pay maintenance fees|
|9 Mar 2014||REIN||Reinstatement after maintenance fee payment confirmed|
|29 Abr 2014||FP||Expired due to failure to pay maintenance fee|
Effective date: 20140309
|30 May 2014||FPAY||Fee payment|
Year of fee payment: 4
|1 Sep 2014||PRDP||Patent reinstated due to the acceptance of a late maintenance fee|
Effective date: 20140902
|30 Sep 2014||AS||Assignment|
Owner name: EMORY UNIVERSITY, GEORGIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:INTAILOR SURGICAL, LLC;REEL/FRAME:033846/0517
Effective date: 20140924
Owner name: INCIRCLE MEDICAL, LLC, GEORGIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BERNARD MEDICAL LLC;REEL/FRAME:033846/0462
Effective date: 20140924
Owner name: INTAILOR SURGICAL, GEORGIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:INCIRCLE MEDICAL, LLC;REEL/FRAME:033846/0479
Effective date: 20140924
Owner name: BERNARD MEDICAL LLC, GEORGIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BJERKEN, DAVID B.;REEL/FRAME:033846/0413
Effective date: 20140924