US20070179564A1 - Treatment of vision disorders using electrical, light, and/or sound energy - Google Patents
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- US20070179564A1 US20070179564A1 US11/731,520 US73152007A US2007179564A1 US 20070179564 A1 US20070179564 A1 US 20070179564A1 US 73152007 A US73152007 A US 73152007A US 2007179564 A1 US2007179564 A1 US 2007179564A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light
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Abstract
A non-invasive ocular therapy for vision disorders is provided. First and second electrodes of a direct current source are electrically contacted so as to deliver current to and/or about an area proximal one or more eyes of a subject. A direct electrical current of between about 1-800 microamps, at a resistance assumption of about 500 ohms, is generated between the electrodes for a preselected duration. Preferably, the direct electrical current is generated at a select frequency profile as a function of time, and with a carrier signal of about 10,000-12,000 hertz. Advantageously, the subject therapy is augmented via application of light energy to the eye(s), as well as by the application of infrasonic sound waves directly into eyes.
Description
- This is an international patent application filed under 35 U.S.C. §363 claiming priority under 35 U.S.C. §119(e)(1) of the following U.S. provisional patent applications: Appl. Ser. No. 60/542,768 filed Feb. 6, 2004; Appl. Ser. No. 60/542,442 filed Feb. 6, 2004; Appl. Ser. No. 60/542,443 filed Feb. 6, 2004; and, Appl. Ser. No. 60/542,724 filed Feb. 6, 2004.
- This invention relates to the treatment of vision disorders (e.g., ocular disease), more particularly, the selective therapeutic application of energy, in the form of electrical, light and/or sound energy, to the eye(s).
- News and knowledge of vision disorders are on the rise. It is estimated that the lifetime costs for all people with vision impairment who were born in 2000 will total $2.5 billion (2003 dollars, see generally, Centers for Disease Control and Prevention, Economic Costs Associated with Mental Retardation, Cerebral Palsy, Hearing Loss, & Vision Impairment, United States, 2003, MMWR 2004; 53:57-9) . These costs include both direct and indirect costs. Direct medical costs, such as doctor visits, prescription drugs, and inpatient hospital stays, make up 6% of these costs. Direct nonmedical expenses, such as home modifications and special education, make up 16% of the costs. Indirect costs, which include the value of lost wages when a person dies early, cannot work, or is limited in the amount or type of work he or she can do, make up 77% of the costs. These estimates do not include other expenses, such as hospital outpatient visits, emergency department visits, and family out-of-pocket expenses. The actual economic costs of vision impairment are, therefore, even higher than what is generally reported.
- The most common causes of vision impairment among adults in the United States are age-related macular degeneration (AMD), presbyopia, diabetic retinopathy, cataracts, and glaucoma. AMD affects the part of the retina that is responsible for sharp central vision and is the leading cause of legal blindness in the United States in persons over 65 years old. According to a March 1997 Review of Optometry Journal, 10% of our population over age 52 has AMD and 33% of individuals over age 75 have AMD. It is estimated that more than 13 million Americans now have AMD and that, by the time the Baby Boomers reach age 65, there will be over 30 million cases of AMD, almost 25% of our population over 65.
- Presbyopia is a frustrating condition that begins to effect the “small print” visual acuity (i.e., blurred vision) of many individuals after they reach forty years of age. People find that they are unable to focus on the small print, and may develop headaches, eyestrain, or feel fatigued. Treatment typically involves buying inexpensive, “off-the-shelf” “reading glasses”, surgery, or bi-focal contact lenses. It is believed that presbyopia occurs from a loss of elasticity or flexibility in the natural lens of the eye of those over forty years of age. During the age-related process, the proteins in the lens begin to make the lens harder, less elastic, with muscle fibers around the lens also effected. As the lens requires elasticity to focus up close, with a diminished or diminishing functionality, visual acuity is impacted.
- Diabetic retinopathy is a common complication of diabetes in which the blood vessels in the retina break down, leak, or become blocked, leading to vision impairment. Cataracts are a clouding of the eye's lens, which is normally clear. Glaucoma is increased fluid and pressure within the eye that leads to enlargement of the eyeball. The risk of vision loss from many of these conditions can often be reduced if the condition is found early and treated.
- Normal retinal cell function is a photochemical reaction converting light energy to an electrical impulse which travels to the brain and vision occurs. With AMD and other visual system diseases, diseased, inflamed retinal cells eventually lose cell function. Adenosine triphosphate (ATP) levels drop, protein synthesis drops, the electrical resistance goes up, and cell electricity potential goes down. Basically, the cells seem to go dormant for a time before they die. It is believed that, if electrical stimulation is provided to the cells before they die, blood vessel permeability is increased, a more normal cellular electrical potential will be achieved, the ATP levels will increase, protein synthesis will occur again, and normal cell metabolism will be restored.
- Additionally, electrical stimulation appears to have a healing effect on the small blood vessels in the retina, promoting a more efficient delivery of nutrients to the retinal cells and a more efficient uptake of proteins that can accumulate on the retina. Thus, it is believed that microcurrent stimulation (i.e., the delivery of typically about less than 1,500 microamps) will help rejuvenate the cells in the retina to slow or stop degeneration of the eye due to AMD and the like. With the proper microcurrent stimulation wave form and therapy procedures, progressive vision disorders may be slowed or stopped in a large number of people suffering therefrom.
- For example, Fedorov et al., U.S. Pat. No. 5,147,284, proposed to treat diseases of the optic nerve and retina by the application of a pulsed 3.5 magnetic flux, the magnetic field induction being from 0.1 T to 0.25 T. However the technique is invasive, requiring exposure of the posterior portion of the eyeball and optic nerve and introduction of the inducer into the orbit.
- Liss et al., U.S. Pat. No. 4,614,193, proposed to treat glaucoma with the application of transcutaneous electrical stimulation, more particularly, the application of pulsed electrical current at a level less than 4 milliamperes, the pulse trains occurring at 12-20 kHz, amplitude modulated at 8-20 hz, and having a 3:1 duty cycle. Applying this waveform through electrodes positioned on the temple and on the ipsilateral hand, Liss et al. achieved an approximately 28% reduction in intraocular pressure in the treated eye. To the knowledge of the inventor, passage of electrical current through the eye, hereinafter “transocular electrical conduction,” has been used in the art for the treatment of blindness disease, but has yet to be maximized as a vision disorder therapy, as for example, via the selection and/or combination of wave forms, power, duration, and frequencies.
- Greenberg et al., U.S. Pat. No. 5,944,747, is generally directed to a method of focused phosphene generation through deeper intermediate retinal cellular electrical stimulation, to the exclusion of direct galleon cellular electrical stimulation, via the application of a long duration stimulation signal. Preferably, the long duration stimulation signal is a biphasic signal having a negative and positive phase pulse. It is further believed to be advantageous to make such biphasic pulses simulate cathodic monophasic pulses by using unequal amplitude phases.
- It is suggested from Wallace et al., U.S. Pat. No. 5,522,864 that a direct current with a constant magnitude of 200 microamps has show positive effect in treating ocular disease including macular degeneration. Further, Jarding et al., U.S. Pat. Nos. 6,035,236 & 6,275,735, suggests that microcurrent stimulation, vis-a-vis the application of microcurrent approximate to an eye wherein the microcurrent has an amplitude of about 50-180 microamps and comprises a sweep wave microcurrent signal produced by a sweep wave signal generator, can improve vision in individuals suffering from additional “blindness” causing diseases, including retinitis pigmentosis. In these instances, the theory for improvement has to do with bringing energy to dormant photo-receptor cells. The inventor believes that the Wallace et al. effort is not expansive enough in both varying the power level and frequency selection/application duration, and further, that the Jarding et al. efforts are too broad in not specifying especially effective therapeutic frequencies. In the Jarding et al. case, this may be due to Jarding et al. attempting to treat a broad range of diseases including cancer which likely require technical considerations that are different from those implicated in overcoming vision disorders.
- Thus there remains a need for an energy based treatment of vision disorders that maximizes therapeutic effect. Furthermore, it is believed advantageous to provide an energy based treatment that includes electrical, light and sound energy forms, alone or in select combination, to effectuate a therapeutic result in persons suffering from vision disorders. Further still, it is believed that improvements in transocular electrical conduction are achieved utilizing specific frequencies, wave forms, durations, and power algorithms in furtherance of maximizing subject visual efficacy.
- It is a primary object of the present invention to provide an improved apparatus and method for the treatment of vision disorders.
- It is another object of the present invention to provide a safe, improved, noninvasive method for the restoration of vision by treating the eye with transocular conduction of electrical current.
- It is yet another object of the present invention to provide a safe, improved, noninvasive method for the restoration of vision by treating the eye with transocular conduction of electrical current supplemented by other energy forms, namely, light and/or sound energy.
- These and other objects of the present invention are attained by a direct current generator that produces an amplitude modulated, low level, pulsed, direct current applied between electrodes, one placed on or proximal a closed eyelid and the other on a remote body location, e.g., a top of the subject's corresponding hand.
- Blindness disease, as a species of vision disorder, is a debilitating ocular disease having hemorrhagic and exudative variants, both of which are susceptible to safe and efficient treatment by the subject invention. Treatment typically results in amelioration of the ophthalmoscopic manifestations of the disorder, and substantial restoration of central visual acuity. For the purpose of this disclosure, “blindness disease” means macular degeneration, presbyopia, retinitis pigmentosis and Stargardt's and may include one or more of: diabetic retinopathy, glaucoma, CMV-retinitis, Best's disease, macular dystrophy, optic neuritis, ischemic anterior optic neuritis, Usher's syndrome, Leber's congenital amaurosis, cone-rod dystrophy, cone dystrophy, choroideremia and gyrate atrophy, central retinal artery occlusion, central retinal vein occlusion, branch retinal artery occlusion, branch retinal vein occlusion, central serous chorioretinopathy, cystoid macular edema, ocular histomplasmosis, ocular toxoplasmosis, retinopathy of prematurity, amblyopia, stabismus, and nystagmus.
- As to the subject invention, more specific features and advantages obtained in view of those features will become apparent with reference to the drawing figures and DETAILED DESCRIPTION OF THE INVENTION.
- Referring now to the drawings wherein like numerals are used to designate like parts of the invention throughout the figures:
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FIG. 1 illustrates a human subject receiving treatment for a vision disorder utilizing the application of microcurrent; -
FIGS. 2-5 depict frequency output for each of the preferred sequences of the frequency profile associated with the electrical stimulation of the subject invention; -
FIG. 6 is a tabulation of Snellen Chart results for a twelve week study of a plurality of patients undergoing the electrical stimulation of the subject invention; and, -
FIG. 7-10 illustrate: Snellen acuity, kinetic fields: horizontal effect in degrees; kinetic fields: vertical effect in degrees; and, Humphrey 30-2, total errors data for pre and post treatment subjects undergoing the electrical stimulation of the subject invention. - The subject therapy is non-invasive, and involves minimally delivering a precise amount of tightly controlled electrical current through electrodes applied to the skin at specific areas at and/or near the eyes. A multi-frequency pulse generator, e.g., a
ScyFIX 600 microcurrent stimulator, commercially available from ScyFIX, LLC of Minnesota, U.S.A., is advantageous for generating direct electrical current between electrodes in furtherance of therapy administration. - With reference to
FIG. 1 , there is shown ahuman subject 20 having at least a single closed lid of aneye 21 in contact with anelectrode 22.Electrode 22 is connected to the positive output of a constantcurrent generator 25 having a suitable power source connected thereto or incorporated therein. The negative output of thegenerator 25 is connected to asecond electrode 24, which is preferably attached to the skin at the proximal hand. When thegenerator 25 is activated, a current loop is established that extends, in order, from thegenerator 25 throughelectrode 22 andeye 21 so as to terminate at thesecond electrode 24. The current loop is completed at thegenerator 25. - In accordance with one aspect of the invention, a vision disorder, more particularly, a blindness disease in a subject is treated by the steps of: placing a first electrode of a direct current source in electrical contact proximal one or more eyes of a subject, as for example, in contact with a closed eyelid thereof; placing a second electrode of the source in electrical contact with a site remote from the position of the first electrode; and, causing a pulsed direct current from 1 to 800 microamps, at a resistance assumption of about 500 ohms, to flow between the electrodes and through the subject for a preselect duration, e.g., about twenty minutes. In a preferred embodiment, up to four discrete frequencies are utilized in the course of the preselected duration, more particularly, a frequency profile is administered wherein, for example, the frequency profile comprises a sequence of about 290 Hz (i.e., 250-300 Hz) for about one minute; about 31 Hz (i.e., 25-35 Hz) for about two minutes; about 8.9 Hz (7-10 Hz) for either about seven or ten minutes (i.e., at least about seven minutes); and, about 0.28 Hz (i.e., 0.15-0.3 Hz) for either about seven or ten minutes (i.e., at least about seven minutes). Associated frequency output charts for each of the preferred sequences of the profile are depicted in
FIGS. 2-5 . The employed frequencies are utilized to amplitude modulate a pulsed carrier signal having a pulse frequency of about 10,000-12,000 Hz. Advantageously, the carrier signal is switched on and off in time and inverted about every 0.5 seconds by reversing the polarity of the signal at the electrodes. - With general and passing references to
FIGS. 6-10 ,FIG. 6 is a tabulation of Snellen Chart results for a twelve week study of a plurality of patients undergoing the electrical stimulation of the subject invention. The paired columns represent pre/post treatment Snellen chart results for right (i.e., OD) and left (i.e., OS) eyes.FIGS. 7-10 illustrate: Snellen acuity, kinetic fields: horizontal effect in degrees; kinetic fields: vertical effect in degrees; and, Humphrey 30-2, total errors data for pre and post treatment subjects undergoing the electrical stimulation of the subject invention. - In accordance with another aspect of the therapy of the subject invention, the source is a portable, battery powered constant direct current generator which is affixed/affixable to the subject. The subject is thus enabled to ambulate while the direct current is flowing there-through. In some circumstances, it may be desired that the eyelid not be closed during treatment. In that case, the electrode of the eye may be positioned around the eye. A frame, such as an eyeglass frame or other easily supportable head structure (not shown), may be fitted with an electrode to position and maintain such an electrode about or near the eye.
- In an alternate embodiment of non-invasive ocular therapy for vision disorders and the like, light energy is applied to one or both eyes of the subject. Preferably, but not necessarily, light energy is applied at a power density of up to about 4.5 joules percentimeter squared. Furthermore, it appears especially advantageous that the light energy have an optical power of about 5 milliwatts percentimeter squared, with the light energy preferably applied at a frequency of about 145 Hz for up to about fifteen minutes.
- It is generally known that certain biochemical conditions in the brain facilitate effective cortical plasticity such that new functions can occur. Neurotransmitters trigger this biochemistry and allow for additional synoptic connections to initiate movement and growth in new directions. Colored light therapy is believed to act as a powerful tool to stimulate the biochemistry of the brain through the visual system by way of the retinal-hypothalamus brain connection.
- With regard to apparatus for effectuating heretofore described therapies, an electrode-carrying structure (e.g., a frame, head band or other head gear) may be fitted with known light emitting devices capable of delivering or administering one or more select frequencies. For example, LEDs or IREDs may be employed to provide light energy of a desired frequency dependent upon the particular blindness disease. Blue-green colors are believed useful for macular degeneration, and other blindness diseases, while red-yellow colors are believed useful for retinitus pigmentosis, and related or similar blindness diseases. Particular wavelength ranges that are believed to be useful are: about 450-500 nm (i.e., more generally, “blue”); about 520-570 nm (i.e., more generally, “green”); about 565-590 nm ((i.e., more generally, “yellow”); and, 625-740 nm (i.e., more generally, “red”). Light therapy at, or including, these wavelength ranges may be advantageously employed for blindness disease.
- In a specific embodiment of the subject therapy, light energy is conducted upon each eye of the subject sequentially between light energy characterized by first and second wavelength ranges. For example, for macular degeneration, the described “frame” or the like may be fitted to direct blue light into one eye and green light into the other while allowing the “colors” to be switched from one treatment cycle to the next, or during an individual treatment cycle. Such approach, utilizing wavelength ranges associated with red/yellow are believed advantageous in treatment of retinitis pigmantosis.
- In addition to the intraocular application of electrical and/or light energy, as described above, it may be additionally beneficial to direct infrasonic sound waves (i.e., those having a frequency generally below 20 Hz) directly into the eye or eyes of the subject. Emitters for such sound waves may be carried by the above described frames, or an adaption thereof. It is believed advantageous, in furtherance of treating vision disorders, to direct infrasonic sound waves into the eye, preferably, but not necessarily, at random frequencies ranging from about 8-14 Hz.
- While the principles under which the invention produces its beneficial effects are not fully understood, and without restriction to a particular theory of operation, transocular electrical conduction as practiced in accordance with the invention may restore cellular electrical balance by changing potentials across cell membranes. This may alter the levels of certain ions and molecules toward a desirable equilibrium. Other physiological effects are believed to be produced: reduction of alkalinity proximate the passage of electrical current and the production of low levels of hydrochloric acid; attraction of oxygen to the region; localized vasoconstriction; reduction of local hemorrhage; sedation; increased tonicity of local tissues; antisepsis; production of desirable fibroplasia; and reduced neuromuscular irritability. Stimulation through the eyes also allows access to more then thirty-three percent of the total blood volume of the body in a twenty minute treatment session. The blood consists of many cells which exist to capture electro-magnetic energy to control and direct biomechanical reactions. This also includes animating and mineralizing the blood by adjusting the pH. Also, with blindness disease, diseased, inflamed retinal cells eventually lose cell function. Adenosine triphosphate (ATP) levels drop, protein synthesis drops, the electrical resistance goes up, and cell membrane electrical potential goes down. Basically, the cells seem to go dormant for a time before they die. So, it is believed that, if electrical stimulation is provided to the cells before they die, blood vessel permeability is increased, a more normal cellular electrical potential will be achieved, the ATP levels will increase, and protein synthesis will occur again.
- It is to be understood the aforementioned therapeutic aspects of electrical, light and sound energy may be administered independently of each other (i.e., each individually), or in one or more select combinations/permutations thereof. Furthermore, there are other variations of the subject invention, some of which will become obvious to those skilled in the art. It will be understood that this disclosure, in many respects, is only illustrative, and is not intended to be limiting. Accordingly, the scope of the subject invention is as defined in the language of the appended claims.
Claims (33)
1-29. (canceled)
30. A non-invasive ocular therapy for vision disorders comprising:
a. electrically contacting a first electrode of a direct current source proximal an eye of a subject;
b. electrically contacting a second electrode of the direct current source to the subject; and,
c. causing an amplitude modulated pulsed carrier signal to pass from one of said electrodes to another of said electrodes, said amplitude modulated pulsed carrier signal being characterized by a polarity inversion.
31. The therapy of claim 30 wherein said polarity inversion is constant.
32. The therapy of claim 30 wherein said polarity inversion is periodic.
33. The therapy of claim 30 wherein the pulsed carrier signal of said amplitude modulated pulsed carrier signal is amplitudinally modulated by a preselect frequency profile sequence.
34. The therapy of claim 33 wherein said preselected frequency profile sequence comprises at least two unique frequencies.
35. The therapy of claim 33 wherein said preselected frequency profile sequence comprises at least three unique frequencies.
36. The therapy of claim 33 wherein said preselected frequency profile sequence comprises at least four unique frequencies.
37. The therapy of claim 33 wherein a frequency of said preselected frequency profile sequence comprises a frequency in a range of about 250-300 Hz.
38. The therapy of claim 33 wherein a frequency of said preselected frequency profile sequence comprises a frequency in a range of about 25-35 Hz.
39. The therapy of claim 33 wherein a frequency of said preselected frequency profile sequence comprises a frequency in a range of about 7-10 Hz.
40. The therapy of claim 33 wherein a frequency of said preselected frequency profile sequence comprises a frequency in a range of about 0.15-0.3 Hz.
41. The therapy of claim 40 wherein a frequency of said preselected frequency profile sequence further comprises a frequency in a range of about 25-35 Hz.
42. The therapy of claim 41 wherein a frequency of said preselected frequency profile sequence further comprises a frequency in a range of about 7-10 Hz.
43. The therapy of claim 42 wherein a frequency of said preselected frequency profile sequence further comprises a frequency in a range of about 0.15-0.3 Hz.
44. The therapy of claim 30 further comprising select application of spectral components of visible light to an eye of the subject.
45. The therapy of claim 44 wherein spectral components of visible light of said select application of spectral components of visible light are selected from the group consisting of blue, green, yellow and red spectral components.
46. The therapy of claim 45 wherein said select application of spectral components of visible light comprises a sequential delivery of at least two spectral components of visible light.
47. The therapy of claim 44 further comprising select application of infrasonic sound waves to the eye of the subject.
48. The therapy of claim 30 further comprising select application of infrasonic sound waves to the eye of the subject.
49. The therapy of claim 48 wherein said infrasonic sound waves are characterized by frequencies in a range from about 8-14 Hz.
50. An ocular therapy for vision disorders comprising directing an inverted pulsed carrier signal through a vision disorder subject, said inverted pulsed carrier signal being amplitudinally modulated by a preselect frequency sequence.
51. The ocular therapy of claim 50 wherein said preselect frequency sequence comprises up to four discrete amplitude modulating frequencies.
52. The ocular therapy of claim 51 wherein said up to four discrete amplitude modulating frequencies includes those selected from a range of about either 250-300 Hz, 25-35 Hz, 7-10 Hz, and/or 0.15-0.3 Hz.
53. The ocular therapy of claim 50 wherein said preselect frequency sequence comprises a first frequency in a range of about 250-300 Hz.
54. The ocular therapy of claim 53 wherein said preselect frequency sequence comprises a second frequency in a range of about 25-35 Hz.
55. The ocular therapy of claim 54 wherein said preselect frequency sequence comprises a third frequency in a range of about 7-10 Hz.
56. The ocular therapy of claim 55 wherein said preselect frequency sequence comprises a fourth frequency in a range of about 0.15-0.3 Hz.
57. The ocular therapy of claim 50 further comprising select application of either of blue, green, yellow or red components of visible light to an eye of the vision disorder subject.
58. The ocular therapy of claim 57 further comprising select application of infrasonic sound waves to the eye of the vision disorder subject.
59. The ocular therapy of claim 50 further comprising select application of infrasonic sound waves to an eye of the vision disorder subject.
60. An apparatus for delivery of non-invasive ocular therapy for vision disorders comprising a head supportable structure equipped with an electrode and means for selectively delivering one or more spectral components of visible light to an eye of a wearer of the head supportable structure, said head supportable structure adapted to pass an amplitude modulated pulsed carrier signal to/from said electrode, said amplitude modulated pulsed carrier signal being characterized by a polarity inversion.
61. The apparatus of claim 51 wherein said head supportable structure further includes means for selectively emitting infrasonic sound waves into the eye of a wearer of the head supportable structure.
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US20100076423A1 (en) * | 2008-09-19 | 2010-03-25 | Avedro, Inc. | Eye therapy system |
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Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
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EP4091660B1 (en) | 2021-05-20 | 2023-10-04 | Subvision S.r.l. | Electrostimulator for vision |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3807838A (en) * | 1973-01-10 | 1974-04-30 | Madison College Foundation Inc | Color vision photometer |
US4989605A (en) * | 1989-03-31 | 1991-02-05 | Joel Rossen | Transcutaneous electrical nerve stimulation (TENS) device |
US5137029A (en) * | 1990-08-17 | 1992-08-11 | Parra Jorge M | Non-invasive ophthalmic diagnostic method and apparatus |
US5522864A (en) * | 1994-10-25 | 1996-06-04 | Wallace; Larry B. | Apparatus and method for ocular treatment |
US6007477A (en) * | 1998-02-12 | 1999-12-28 | Demenezes; Jose E. | Eye treatment device |
US6424864B1 (en) * | 1997-11-28 | 2002-07-23 | Masayuki Matsuura | Method and apparatus for wave therapy |
US7251528B2 (en) * | 2004-02-06 | 2007-07-31 | Scyfix, Llc | Treatment of vision disorders using electrical, light, and/or sound energy |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4614193A (en) * | 1984-01-09 | 1986-09-30 | Pain Suppression Labs, Inc. | Electronic glaucoma treatment apparatus and methodology |
FR2773320B1 (en) | 1998-01-05 | 2000-03-03 | Optisinvest | DEVICE FOR INTRAOCULAR TRANSFER OF ACTIVE PRODUCTS BY IONTOPHORESIS |
US5935155A (en) | 1998-03-13 | 1999-08-10 | John Hopkins University, School Of Medicine | Visual prosthesis and method of using same |
US5944747A (en) | 1998-03-13 | 1999-08-31 | Johns Hopkins University | Method for preferential outer retinal stimulation |
US6035236A (en) | 1998-07-13 | 2000-03-07 | Bionergy Therapeutics, Inc. | Methods and apparatus for electrical microcurrent stimulation therapy |
US6006756A (en) | 1998-08-03 | 1999-12-28 | Shadduck; John H. | Non-contact magnetoresonant implant system and techniques for periodic corneal re-shaping |
US6101411A (en) | 1998-09-24 | 2000-08-08 | Newsome; David A. | Dilation enhancer |
US6282449B1 (en) | 1998-10-21 | 2001-08-28 | William Kamerling | Method and device for causing the eye to focus on a near object |
US20040106965A1 (en) | 2001-06-29 | 2004-06-03 | Chow Alan Y. | Methods and apparatus for treatment of degenerative retinal disease via indirect electrical stimulation |
US20050004625A1 (en) | 2001-06-29 | 2005-01-06 | Chow Alan Y. | Treatment of degenerative retinal disease via electrical stimulation of surface structures |
JP2005529689A (en) | 2002-06-13 | 2005-10-06 | アトランティク・メディカル・インク | Transcutaneous electrical nerve stimulator and method using weak current |
US7158834B2 (en) | 2002-06-13 | 2007-01-02 | Atlantic Medical, Inc. | Method and apparatus for performing microcurrent stimulation (MSC) therapy |
US20050137649A1 (en) | 2002-06-13 | 2005-06-23 | Paul Edward L.Jr. | Method and apparatus for performing microcurrent stimulation (MSC) therapy |
US6990377B2 (en) | 2003-04-24 | 2006-01-24 | Northstar Neuroscience, Inc. | Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation |
-
2005
- 2005-02-07 AU AU2005212306A patent/AU2005212306B2/en not_active Ceased
- 2005-02-07 CA CA2556222A patent/CA2556222C/en active Active
- 2005-02-07 US US10/565,544 patent/US7251528B2/en active Active
- 2005-02-07 JP JP2006552296A patent/JP2007521124A/en active Pending
- 2005-02-07 WO PCT/US2005/003695 patent/WO2005077452A1/en active Application Filing
-
2007
- 2007-03-30 US US11/694,491 patent/US20070179563A1/en not_active Abandoned
- 2007-03-30 US US11/731,520 patent/US20070179564A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3807838A (en) * | 1973-01-10 | 1974-04-30 | Madison College Foundation Inc | Color vision photometer |
US4989605A (en) * | 1989-03-31 | 1991-02-05 | Joel Rossen | Transcutaneous electrical nerve stimulation (TENS) device |
US5137029A (en) * | 1990-08-17 | 1992-08-11 | Parra Jorge M | Non-invasive ophthalmic diagnostic method and apparatus |
US5522864A (en) * | 1994-10-25 | 1996-06-04 | Wallace; Larry B. | Apparatus and method for ocular treatment |
US6424864B1 (en) * | 1997-11-28 | 2002-07-23 | Masayuki Matsuura | Method and apparatus for wave therapy |
US6007477A (en) * | 1998-02-12 | 1999-12-28 | Demenezes; Jose E. | Eye treatment device |
US7251528B2 (en) * | 2004-02-06 | 2007-07-31 | Scyfix, Llc | Treatment of vision disorders using electrical, light, and/or sound energy |
Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100324441A1 (en) * | 2002-02-04 | 2010-12-23 | Hargrove Jeffrey B | Brain-Related Chronic Pain Disorder Treatment Method and Apparatus |
US8992516B2 (en) | 2007-07-19 | 2015-03-31 | Avedro, Inc. | Eye therapy system |
US8652131B2 (en) | 2007-07-19 | 2014-02-18 | Avedro, Inc. | Eye therapy system |
US20090024117A1 (en) * | 2007-07-19 | 2009-01-22 | Avedro, Inc. | Eye therapy system |
US8202272B2 (en) | 2007-07-19 | 2012-06-19 | Avedro, Inc. | Eye therapy system |
US8409189B2 (en) | 2008-01-23 | 2013-04-02 | Avedro, Inc. | System and method for reshaping an eye feature |
US20090187184A1 (en) * | 2008-01-23 | 2009-07-23 | David Muller | System and method for reshaping an eye feature |
US20090187178A1 (en) * | 2008-01-23 | 2009-07-23 | David Muller | System and method for positioning an eye therapy device |
US8469952B2 (en) | 2008-01-23 | 2013-06-25 | Avedro, Inc. | System and method for positioning an eye therapy device |
US20090187173A1 (en) * | 2008-01-23 | 2009-07-23 | David Muller | System and method for reshaping an eye feature |
US8348935B2 (en) | 2008-01-23 | 2013-01-08 | Avedro, Inc. | System and method for reshaping an eye feature |
US8398628B2 (en) | 2008-09-19 | 2013-03-19 | Avedro, Inc. | Eye therapy system |
US20100076423A1 (en) * | 2008-09-19 | 2010-03-25 | Avedro, Inc. | Eye therapy system |
US20100094280A1 (en) * | 2008-10-01 | 2010-04-15 | Avedro, Inc. | Eye therapy system |
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US8460278B2 (en) | 2008-10-01 | 2013-06-11 | Avedro, Inc. | Eye therapy system |
US20100185192A1 (en) * | 2008-11-11 | 2010-07-22 | Avedro, Inc. | Eye therapy system |
US8882757B2 (en) | 2008-11-11 | 2014-11-11 | Avedro, Inc. | Eye therapy system |
US8712536B2 (en) | 2009-04-02 | 2014-04-29 | Avedro, Inc. | Eye therapy system |
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US8177778B2 (en) | 2009-10-30 | 2012-05-15 | Avedro, Inc. | System and method for stabilizing corneal tissue after treatment |
WO2013190057A1 (en) * | 2012-06-22 | 2013-12-27 | Baklayan Alan E | Therapy device and method for controlling such a therapy device |
CN104487133A (en) * | 2012-06-22 | 2015-04-01 | 艾伦·E·伯克莱恩 | Therapy device and method for controlling such therapy device |
WO2015158379A1 (en) * | 2014-04-16 | 2015-10-22 | Baklayan Alan E | Therapy device for producing electromagnetic oscillations |
US11338139B2 (en) * | 2018-10-01 | 2022-05-24 | Biovisics Medical, Inc. | System and methods for controlled electrical modulation for vision therapy |
US11305118B2 (en) | 2018-11-30 | 2022-04-19 | Biovisics Medical, Inc. | Head worn apparatuses for vision therapy |
US11471680B2 (en) | 2019-04-10 | 2022-10-18 | Biovisics, Inc. | Systems and interfaces for ocular therapy |
WO2020252278A1 (en) * | 2019-06-14 | 2020-12-17 | Biovisics Medical, Inc. | Wearable medical device |
US11511112B2 (en) | 2019-06-14 | 2022-11-29 | Biovisics Medical, Inc. | Wearable medical device |
WO2021011255A1 (en) * | 2019-07-12 | 2021-01-21 | Biovisics Medical, Inc. | Ocular therapy modes and systems |
Also Published As
Publication number | Publication date |
---|---|
WO2005077452A1 (en) | 2005-08-25 |
AU2005212306B2 (en) | 2010-07-01 |
US20070179563A1 (en) | 2007-08-02 |
AU2005212306A1 (en) | 2005-08-25 |
JP2007521124A (en) | 2007-08-02 |
US7251528B2 (en) | 2007-07-31 |
US20060217783A1 (en) | 2006-09-28 |
CA2556222A1 (en) | 2005-08-25 |
CA2556222C (en) | 2014-01-28 |
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