US20080197035A1 - Sharps Container System for Two Piece Injection Device - Google Patents
Sharps Container System for Two Piece Injection Device Download PDFInfo
- Publication number
- US20080197035A1 US20080197035A1 US12/109,079 US10907908A US2008197035A1 US 20080197035 A1 US20080197035 A1 US 20080197035A1 US 10907908 A US10907908 A US 10907908A US 2008197035 A1 US2008197035 A1 US 2008197035A1
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- United States
- Prior art keywords
- tip segment
- dispensing chamber
- sharps container
- disposable tip
- limited reuse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8262—Internal energy supply devices connectable to external power source, e.g. connecting to automobile battery through the cigarette lighter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/484—Regulating injection pressure
Definitions
- the present invention relates to a single-use medical device and more particularly to a keyed safety cap and matching receptacle for two-piece ophthalmic injection device with a disposable tip.
- Age related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathies (e.g., diabetic retinopathy, vitreoretinopathy), retinitis (e.g., cytomegalovirus (CMV) retinitis), uveitis, macular edema, glaucoma, and neuropathies are several examples.
- AMD Age related macular degeneration
- CNV choroidal neovascularization
- retinopathies e.g., diabetic retinopathy, vitreoretinopathy
- retinitis e.g., cytomegalovirus (CMV) retinitis
- uveitis macular edema
- glaucoma glaucoma
- neuropathies are several examples.
- FIG. 1 is a perspective view of a prior art syringe used to inject drugs into the eye.
- the syringe includes a needle 105 , a luer hub 110 , a chamber 115 , a plunger 120 , a plunger shaft 125 , and a thumb rest 130 .
- the drug to be injected is located in chamber 115 . Pushing on the thumb rest 130 causes the plunger 120 to expel the drug through needle 105 .
- the surgeon is required to pierce the eye tissue with the needle, hold the syringe steady, and actuate the syringe plunger (with or without the help of a nurse) to inject the fluid into the eye.
- the volume injected is typically not controlled in an accurate manner because reading the vernier is subject to parallax error. Fluid flow rates are uncontrolled and tissue damage may occur due to an “unsteady” injection. Reflux of the drug may also occur when the needle is removed from the eye.
- a commercially available fluid dispenser is the ULTRATM positive displacement dispenser available from EFD Inc. of Buffalo, R.I.
- the ULTRA dispenser is typically used in the dispensing of small volumes of industrial adhesives. It utilizes a conventional syringe and a custom dispensing tip. The syringe plunger is actuated using an electrical stepper motor and an actuating fluid.
- Parker Hannifin Corporation of Cleveland, Ohio distributes a small volume liquid dispenser for drug discovery applications made by Aurora Instruments LLC of San Diego, Calif.
- the Parker/Aurora dispenser utilizes a piezo-electric dispensing mechanism.
- Ypsomed, Inc. of Switzerland produces a line of injection pens and automated injectors primarily for the self-injection of insulin or hormones by a patient. This product line includes simple disposable pens and electronically-controlled motorized injectors.
- U.S. Pat. No. 6,290,690 discloses an ophthalmic system for injecting a viscous fluid (e.g. silicone oil) into the eye while simultaneously aspirating a second viscous fluid (e.g. perflourocarbon liquid) from the eye in a fluid/fluid exchange during surgery to repair a retinal detachment or tear.
- the system includes a conventional syringe with a plunger.
- One end of the syringe is fluidly coupled to a source of pneumatic pressure that provides a constant pneumatic pressure to actuate the plunger.
- the other end of the syringe is fluidly coupled to an infusion cannula via tubing to deliver the viscous fluid to be injected.
- a portable hand piece for injecting a drug into the eye.
- a hand piece can include a limited reuse assembly attachable to and removable from a disposable tip segment.
- the disposable tip segment contains the drug, a needle for administering the drug, and a temperature control device, such as a heater, for altering the temperature of the drug.
- a temperature control device such as a heater
- the present invention is a sharps container including a cavity for receiving a device with a needle and an opening configured to engage the device so that the device is held in place while a limited reuse assembly is removed from the device.
- the present invention is a sharps container system including a disposable tip segment and a sharps container.
- the disposable tip segment has a dispensing chamber, a needle fluidly coupled to the dispensing chamber, and a housing at least partially enclosing the dispensing chamber.
- the sharps container has a cavity for receiving the disposable tip segment, and an opening configured to engage the disposable tip segment so that the disposable tip segment is held in place while a limited reuse assembly is removed from the disposable tip segment.
- FIG. 1 is a perspective view of a prior art syringe.
- FIG. 2 is a view of an ophthalmic medical device including a disposable tip segment and a limited reuse assembly according to the principles of the present invention.
- FIG. 3 is an embodiment of a limited reuse assembly according to the principles of the present invention.
- FIG. 4 is a cross section view of a disposable tip segment and a limited reuse assembly according to the principles of the present invention.
- FIG. 5 is a cross section view of a disposable tip segment according to the principles of the present invention.
- FIG. 6 is a top view of a sharps container according to the principles of the present invention.
- FIG. 2 depicts one view of an ophthalmic medical device including a disposable tip segment and a limited reuse assembly according to an embodiment of the present invention.
- the medical device includes a tip segment 205 and a limited reuse assembly 250 .
- the tip segment 205 includes a needle 210 , a housing 215 , and an optional light 275 .
- the limited reuse assembly 250 includes a housing 255 , a switch 270 , a lock mechanism 265 , and a threaded portion 260 .
- Tip segment 205 is capable of being connected to and removed from limited reuse assembly 250 .
- tip segment 205 has a threaded portion on an interior surface of housing 215 that screws onto the threaded portion 260 of limited reuse assembly 250 .
- lock mechanism 265 secures tip segment 215 to limited reuse assembly 250 .
- Lock mechanism 265 may be in the form of a button, a sliding switch, or a cantilevered mechanism.
- Other mechanisms for connecting tip segment 205 to limited reuse assembly 250 such as those involving structural features that mate with each other, are commonly known in the art and are within the scope of the present invention.
- Needle 210 is adapted to deliver a substance, such as a drug, into an eye. Needle 210 may be of any commonly known configuration. Preferably, needle 210 is designed such that its thermal characteristics are conducive to the particular drug delivery application. For example, when a heated drug is to be delivered, needle 210 may be relatively short (several millimeters) in length to facilitate proper delivery of the drug based on thermal characteristics.
- Switch 270 is adapted to provide an input to the system.
- switch 270 may be used to activate the system or to turn on a heater.
- Other switches, buttons, or user-directed control inputs are commonly known and may be employed with limited reuse assembly 250 and/or tip segment 205 .
- Optional light 275 is illuminated when tip segment 205 is ready to be used.
- Optional light 275 may protrude from housing 215 , or it may be contained within housing 215 , in which case, optional light 275 may be seen through a clear portion of housing 215 .
- optional light 275 may be replaced by an indicator, such as a liquid crystal display, segmented display, or other device that indicates a status or condition of disposable tip segment 205 .
- optional light 275 may also pulse on and off to indicate other states, such as, but not limited to a system error, fully charged battery, insufficiently charged battery or faulty connection between the tip segment 205 and limited use assembly 250 . While shown on tip segment 205 , optional light 275 or other indicator may be located on limited reuse assembly 250 .
- FIG. 3 is another embodiment of a limited reuse assembly according to the principles of the present invention.
- Limited reuse assembly 250 includes a button 310 , a display 320 , and a housing 330 .
- Disposable tip segment 205 attaches to end 340 of limited reuse assembly 250 .
- Button 310 is actuated to provide an input to the system. As with switch 270 , button 310 may activate a heater or other temperature control device or initiate actuation of a plunger.
- Display 320 is a liquid crystal display, segmented display, or other device that indicates a status or condition of disposable tip segment 205 or limited reuse assembly 250 .
- FIG. 4 is a cross section view of a disposable tip segment and a limited reuse assembly according to an embodiment of the present invention.
- FIG. 4 shows how tip segment 205 interfaces with limited reuse assembly 250 .
- tip segment 205 includes plunger interface 420 , plunger 415 , dispensing chamber housing 425 , tip segment housing 215 , temperature control device 450 , thermal sensor 460 , needle 210 , dispensing chamber 405 , interface 530 , and tip interface connector 520 .
- Limited reuse assembly 250 includes mechanical linkage 545 , actuator shaft 510 , actuator 515 , power source 505 , controller 305 , limited reuse assembly housing 255 , interface 535 , and limited reuse assembly interface connector 525 .
- plunger interface 420 is located on one end of plunger 415 .
- the other end of plunger 415 forms one end of dispensing chamber 405 .
- Plunger 415 is adapted to slide within dispensing chamber 405 .
- An outer surface of plunger 415 is fluidly sealed to the inner surface of dispensing chamber housing 425 .
- Dispensing chamber housing 425 surrounds the dispensing chamber 405 .
- dispensing chamber housing 425 has a cylindrical shape.
- dispensing chamber 405 also has a cylindrical shape.
- Needle 210 is fluidly coupled to dispensing chamber 405 .
- a substance contained in dispensing chamber 405 can pass through needle 210 and into an eye.
- Temperature control device 450 at least partially surrounds dispensing chamber housing 425 .
- temperature control device 450 is adapted to heat and/or cool dispensing chamber housing 425 and any substance contained in dispensing chamber 405 .
- Interface 530 connects temperature control device 450 and thermal sensor 460 with tip interface connector 520 .
- tip segment 205 The components of tip segment 205 , including dispensing chamber housing 425 , temperature control device 450 , and plunger 415 are at least partially enclosed by tip segment housing 215 .
- plunger 415 is sealed to the interior surface of dispensing chamber housing 425 . This seal prevents contamination of any substance contained in dispensing chamber 405 . For medical purposes, such a seal is desirable. This seal can be located at any point on plunger 415 or dispensing chamber housing 425 .
- power source 505 provides power to actuator 515 .
- An interface (not shown) between power source 505 and actuator 515 serves as a conduit for providing power to actuator 515 .
- Actuator 515 is connected to actuator shaft 510 .
- actuator shaft 510 is integral with actuator 515 .
- Mechanical linkage interface 545 is connected to actuator shaft 510 . In this configuration, as actuator 515 moves actuator shaft 510 upward toward needle 210 mechanical linkage interface 545 also moves upward toward needle 210 .
- Controller 305 is connected via interface 535 to limited reuse assembly interface connecter 525 .
- Limited reuse assembly interface connecter 525 is located on a top surface of limited reuse assembly housing 255 adjacent to mechanical linkage interface 545 . In this manner, both limited reuse assembly interface connector 525 and mechanical linkage interface 545 are adapted to be connected with tip interface connector 520 and plunger interface 420 respectively.
- Controller 305 and actuator 515 are connected by an interface (not shown). This interface (not shown) allows controller 305 to control the operation of actuator 515 . In addition, an interface (not shown) between power source 505 and controller 305 allows controller 305 to control operation of power source 505 . In such a case, controller 305 may control the charging and the discharging of power source 505 when power source 505 is a rechargeable battery.
- Controller 305 is typically an integrated circuit with power, input, and output pins capable of performing logic functions.
- controller 305 is a targeted device controller.
- controller 305 performs specific control functions targeted to a specific device or component, such as a temperature control device or a power supply.
- a temperature control device controller has the basic functionality to control a temperature control device.
- controller 305 is a microprocessor.
- controller 305 is programmable so that it can function to control more than one component of the device.
- controller 305 is not a programmable microprocessor, but instead is a special purpose controller configured to control different components that perform different functions. While depicted as one component, controller 305 may be made of many different components or integrated circuits.
- Tip segment 205 is adapted to mate with or attach to limited reuse assembly 250 as previously described.
- plunger interface 420 located on a bottom surface of plunger 415 is adapted to mate with mechanical linkage interface 545 located near a top surface of limited reuse assembly housing 255 .
- tip interface connector 520 is adapted to connect with limited reuse assembly interface connector 525 .
- actuator 515 and actuator shaft 510 are adapted to drive plunger 415 upward toward needle 210 .
- an interface is formed between controller 305 and temperature control device 450 . A signal can pass from controller 305 to temperature control device 450 through interface 535 , limited reuse assembly interface connector 525 , tip interface connector 520 , and interface 530 .
- controller 305 controls the operation of actuator 515 .
- Actuator 515 is actuated and actuator shaft 510 is moved upward toward needle 210 .
- mechanical linkage interface 545 which is mated with plunger interface 420 , moves plunger 415 upward toward needle 210 .
- a substance located in dispensing chamber 405 is then expelled through needle 210 .
- controller 305 controls the operation of temperature control device 450 .
- Temperature control device 450 is adapted to heat and/or cool dispensing chamber housing 425 . Since dispensing chamber housing 425 is at least partially thermally conductive, heating or cooling dispensing chamber housing 425 heats or cools a substance located in dispensing chamber 405 . Temperature information can be transferred from thermal sensor 460 to controller 305 via any of a number of different interface configurations. This temperature information can be used to control the operation of temperature control device 450 .
- controller 305 controls the amount of current that is sent to temperature control device 450 . The more current sent to temperature control device 450 , the hotter it gets.
- controller 305 can use a feed back loop utilizing information from thermal sensor 460 to control the operation of temperature control device 450 .
- Any suitable type of control algorithm such as a proportional integral derivative (PID) algorithm, can be used to control the operation of temperature control device 450 .
- PID proportional integral derivative
- FIG. 5 is a cross section view of a disposable tip segment for an ophthalmic medical device according to an embodiment of the present invention.
- disposable tip segment 205 includes housing 215 , needle 210 , plunger 415 , plunger interface 420 , dispensing chamber 405 , dispensing chamber housing 425 , temperature control device 450 , thermal sensor 460 , interface 530 , locking tabs 557 and 558 , and tip interface connector 520 .
- Disposable tip segment 205 operates as a disposable injection device.
- plunger 415 is located in dispensing chamber housing 425 .
- Dispensing chamber 405 is enclosed by dispensing chamber housing 425 and plunger 415 .
- Plunger 415 forms a fluid seal with the interior surface of dispensing chamber housing 425 .
- Needle 210 is fluidly coupled to dispensing chamber 405 . In this manner, a substance located in dispensing chamber 405 can be contacted by plunger 415 and pushed out of needle 210 .
- Temperature control device 450 is located adjacent to dispensing chamber housing 425 and at least partially surrounds dispensing chamber 405 .
- Housing 215 forms an outer skin on disposable tip segment 205 .
- temperature control device 450 is a heating and/or a cooling device. Temperature control device 450 is in thermal contact with dispensing chamber housing 425 . As such, temperature control device 450 is capable of changing the temperature of the substance in dispensing chamber 405 . Interface 530 and tip interface connector 520 couple temperature control device 450 to a limited reuse assembly. In such a case, temperature control device 450 can be powered and controlled by the limited reuse assembly. In one embodiment of the present invention, temperature control device 450 receives voltage via interface 530 from a limited reuse assembly. Providing a positive voltage across the temperature control device 450 causes it to produce heat. Providing a negative voltage across the temperature control device 450 causes it to cool.
- a substance to be delivered into an eye is located in dispensing chamber 405 .
- the substance is contacted by the inner surface of dispensing chamber housing 425 and one face of plunger 415 .
- dispensing chamber 405 is cylindrical in shape.
- Temperature control device 450 is in thermal contact with dispensing chamber housing 425 . In this manner, temperature control device 450 is adapted to control the temperature of the contents of dispensing chamber 425 .
- Thermal sensor 460 provides temperature information to assist in controlling the operation of temperature control device 450 .
- the substance located in dispensing chamber 405 is a drug that is preloaded into the dispensing chamber.
- disposable tip segment 205 is appropriate as a single use consumable product.
- Such a disposable product can be assembled at a factory with a dosage of a drug installed.
- a set quantity of the drug can be preloaded. For example, 100 microliters of a drug can be loaded into dispensing chamber 405 , and any quantity up to 100 microliters can be dispensed. In such a case, the plunger 415 can be moved a precise distance to deliver a precise dosage of drug from the dispensing chamber 405 , through the needle 210 , and into an eye. This provides for flexibility of dosing and for ease of assembly.
- Locking tabs 557 and 558 are to mate with slots in a limited reuse assembly 250 .
- tip segment 205 is configured to be inserted into a limited reuse assembly 205 and rotated (preferably about a quarter turn) so that tip segment 205 is securely attached to limited reuse assembly 250 .
- locking tabs 557 and 558 are inserted into slots in limited reuse assembly 250 that extend circumferentially at least a portion of the way around an interior surface of limited reuse assembly. As such, tip segment 205 is rotated and locked onto limited reuse assembly 250 .
- FIG. 6 is a top view of a sharps container according to the principles of the present invention.
- Sharps container 600 has an opening 610 that is configured to receive a disposable tip segment 205 .
- a sharps container allows for the safe disposal of needles, such as those used in injection devices.
- a sharps container should be configured to receive the disposable tip segment 205 after it is used. In such a manner, disposable tip segment can be discarded safely.
- Opening 610 is configured to receive tip segment 205 .
- a tip segment 205 is inserted into opening 610 while still connected to a limited reuse assembly 250 .
- Opening 610 engages tip segment 205 so that limited reuse assembly 250 can be rotated to disconnect it from tip segment 205 .
- Limited reuse assembly 250 is then removed, and tip segment 205 falls into sharps container 600 .
- Opening 610 is configured so that it holds tip segment 205 . As such, tip segment 205 does not rotate when an attached limited reuse assembly 250 is rotated. This configuration allows disengagement of tip segment 205 from limited reuse assembly 250 . Opening 610 can be configured with any of a number of different shapes, surfaces, or protrusions that engage a limited reuse assembly 205 to hold it in place.
Abstract
A sharps container system includes a disposable tip segment and a sharps container. The disposable tip segment has a dispensing chamber, a needle fluidly coupled to the dispensing chamber, and a housing at least partially enclosing the dispensing chamber. The sharps container has a cavity for receiving the disposable tip segment and an opening configured to engage the disposable tip segment so that the disposable tip segment is held in place while a limited reuse assembly is removed from the disposable tip segment.
Description
- This application is a continuation-in-part of U.S. Patent Application No. 60/921,497 filed Oct. 16, 2006, U.S. Patent Application No. 60/921,498 filed Oct. 16, 2006, U.S. Patent Application No. 60/921,499 filed Oct. 16, 2006, and is related to U.S. patent application Ser. No. 11/435,906 filed May 17, 2006.
- The present invention relates to a single-use medical device and more particularly to a keyed safety cap and matching receptacle for two-piece ophthalmic injection device with a disposable tip.
- Several diseases and conditions of the posterior segment of the eye threaten vision. Age related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathies (e.g., diabetic retinopathy, vitreoretinopathy), retinitis (e.g., cytomegalovirus (CMV) retinitis), uveitis, macular edema, glaucoma, and neuropathies are several examples.
- These, and other diseases, can be treated by injecting a drug into the eye. Such injections are typically done manually using a conventional syringe and needle.
FIG. 1 is a perspective view of a prior art syringe used to inject drugs into the eye. InFIG. 1 , the syringe includes aneedle 105, aluer hub 110, achamber 115, aplunger 120, aplunger shaft 125, and athumb rest 130. As is commonly known, the drug to be injected is located inchamber 115. Pushing on thethumb rest 130 causes theplunger 120 to expel the drug throughneedle 105. - In using such a syringe, the surgeon is required to pierce the eye tissue with the needle, hold the syringe steady, and actuate the syringe plunger (with or without the help of a nurse) to inject the fluid into the eye. The volume injected is typically not controlled in an accurate manner because reading the vernier is subject to parallax error. Fluid flow rates are uncontrolled and tissue damage may occur due to an “unsteady” injection. Reflux of the drug may also occur when the needle is removed from the eye.
- An effort has been made to control the delivery of small amounts of liquids. A commercially available fluid dispenser is the ULTRA™ positive displacement dispenser available from EFD Inc. of Providence, R.I. The ULTRA dispenser is typically used in the dispensing of small volumes of industrial adhesives. It utilizes a conventional syringe and a custom dispensing tip. The syringe plunger is actuated using an electrical stepper motor and an actuating fluid. Parker Hannifin Corporation of Cleveland, Ohio distributes a small volume liquid dispenser for drug discovery applications made by Aurora Instruments LLC of San Diego, Calif. The Parker/Aurora dispenser utilizes a piezo-electric dispensing mechanism. Ypsomed, Inc. of Switzerland produces a line of injection pens and automated injectors primarily for the self-injection of insulin or hormones by a patient. This product line includes simple disposable pens and electronically-controlled motorized injectors.
- U.S. Pat. No. 6,290,690 discloses an ophthalmic system for injecting a viscous fluid (e.g. silicone oil) into the eye while simultaneously aspirating a second viscous fluid (e.g. perflourocarbon liquid) from the eye in a fluid/fluid exchange during surgery to repair a retinal detachment or tear. The system includes a conventional syringe with a plunger. One end of the syringe is fluidly coupled to a source of pneumatic pressure that provides a constant pneumatic pressure to actuate the plunger. The other end of the syringe is fluidly coupled to an infusion cannula via tubing to deliver the viscous fluid to be injected.
- It would be desirable to have a portable hand piece for injecting a drug into the eye. Such a hand piece can include a limited reuse assembly attachable to and removable from a disposable tip segment. The disposable tip segment contains the drug, a needle for administering the drug, and a temperature control device, such as a heater, for altering the temperature of the drug. In order to protect medical personnel who are handling the two-part device, a special sharps container is needed.
- In one embodiment consistent with the principles of the present invention, the present invention is a sharps container including a cavity for receiving a device with a needle and an opening configured to engage the device so that the device is held in place while a limited reuse assembly is removed from the device.
- In another embodiment consistent with the principles of the present invention, the present invention is a sharps container system including a disposable tip segment and a sharps container. The disposable tip segment has a dispensing chamber, a needle fluidly coupled to the dispensing chamber, and a housing at least partially enclosing the dispensing chamber. The sharps container has a cavity for receiving the disposable tip segment, and an opening configured to engage the disposable tip segment so that the disposable tip segment is held in place while a limited reuse assembly is removed from the disposable tip segment.
- It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are intended to provide further explanation of the invention as claimed. The following description, as well as the practice of the invention, set forth and suggest additional advantages and purposes of the invention.
- The accompanying figures, which are incorporated in and constitute a part of this specification, illustrate several embodiments of the invention and together with the description, serve to explain the principles of the invention.
-
FIG. 1 is a perspective view of a prior art syringe. -
FIG. 2 is a view of an ophthalmic medical device including a disposable tip segment and a limited reuse assembly according to the principles of the present invention. -
FIG. 3 is an embodiment of a limited reuse assembly according to the principles of the present invention. -
FIG. 4 is a cross section view of a disposable tip segment and a limited reuse assembly according to the principles of the present invention. -
FIG. 5 is a cross section view of a disposable tip segment according to the principles of the present invention. -
FIG. 6 is a top view of a sharps container according to the principles of the present invention. - Reference is now made in detail to the exemplary embodiments of the invention, examples of which are illustrated in the accompanying figures. Wherever possible, the same reference numbers are used throughout the figures to refer to the same or like parts.
-
FIG. 2 depicts one view of an ophthalmic medical device including a disposable tip segment and a limited reuse assembly according to an embodiment of the present invention. InFIG. 2 , the medical device includes atip segment 205 and alimited reuse assembly 250. Thetip segment 205 includes aneedle 210, ahousing 215, and anoptional light 275. Thelimited reuse assembly 250 includes ahousing 255, aswitch 270, alock mechanism 265, and a threadedportion 260. -
Tip segment 205 is capable of being connected to and removed fromlimited reuse assembly 250. In this embodiment,tip segment 205 has a threaded portion on an interior surface ofhousing 215 that screws onto the threadedportion 260 oflimited reuse assembly 250. In addition,lock mechanism 265 securestip segment 215 tolimited reuse assembly 250.Lock mechanism 265 may be in the form of a button, a sliding switch, or a cantilevered mechanism. Other mechanisms for connectingtip segment 205 tolimited reuse assembly 250, such as those involving structural features that mate with each other, are commonly known in the art and are within the scope of the present invention. -
Needle 210 is adapted to deliver a substance, such as a drug, into an eye.Needle 210 may be of any commonly known configuration. Preferably,needle 210 is designed such that its thermal characteristics are conducive to the particular drug delivery application. For example, when a heated drug is to be delivered,needle 210 may be relatively short (several millimeters) in length to facilitate proper delivery of the drug based on thermal characteristics. -
Switch 270 is adapted to provide an input to the system. For example, switch 270 may be used to activate the system or to turn on a heater. Other switches, buttons, or user-directed control inputs are commonly known and may be employed withlimited reuse assembly 250 and/ortip segment 205. -
Optional light 275 is illuminated whentip segment 205 is ready to be used.Optional light 275 may protrude fromhousing 215, or it may be contained withinhousing 215, in which case,optional light 275 may be seen through a clear portion ofhousing 215. In other embodiments,optional light 275 may be replaced by an indicator, such as a liquid crystal display, segmented display, or other device that indicates a status or condition ofdisposable tip segment 205. For example,optional light 275 may also pulse on and off to indicate other states, such as, but not limited to a system error, fully charged battery, insufficiently charged battery or faulty connection between thetip segment 205 andlimited use assembly 250. While shown ontip segment 205,optional light 275 or other indicator may be located onlimited reuse assembly 250. -
FIG. 3 is another embodiment of a limited reuse assembly according to the principles of the present invention.Limited reuse assembly 250 includes abutton 310, adisplay 320, and ahousing 330.Disposable tip segment 205 attaches to end 340 oflimited reuse assembly 250.Button 310 is actuated to provide an input to the system. As withswitch 270,button 310 may activate a heater or other temperature control device or initiate actuation of a plunger.Display 320 is a liquid crystal display, segmented display, or other device that indicates a status or condition ofdisposable tip segment 205 orlimited reuse assembly 250. -
FIG. 4 is a cross section view of a disposable tip segment and a limited reuse assembly according to an embodiment of the present invention.FIG. 4 shows howtip segment 205 interfaces withlimited reuse assembly 250. In the embodiment ofFIG. 4 ,tip segment 205 includesplunger interface 420,plunger 415, dispensingchamber housing 425,tip segment housing 215,temperature control device 450,thermal sensor 460,needle 210, dispensingchamber 405,interface 530, andtip interface connector 520.Limited reuse assembly 250 includesmechanical linkage 545,actuator shaft 510,actuator 515,power source 505,controller 305, limitedreuse assembly housing 255,interface 535, and limited reuseassembly interface connector 525. - In
tip segment 205,plunger interface 420 is located on one end ofplunger 415. The other end ofplunger 415 forms one end of dispensingchamber 405.Plunger 415 is adapted to slide within dispensingchamber 405. An outer surface ofplunger 415 is fluidly sealed to the inner surface of dispensingchamber housing 425. Dispensingchamber housing 425 surrounds the dispensingchamber 405. Typically, dispensingchamber housing 425 has a cylindrical shape. As such, dispensingchamber 405 also has a cylindrical shape. -
Needle 210 is fluidly coupled to dispensingchamber 405. In such a case, a substance contained in dispensingchamber 405 can pass throughneedle 210 and into an eye.Temperature control device 450 at least partially surrounds dispensingchamber housing 425. In this case,temperature control device 450 is adapted to heat and/or cool dispensingchamber housing 425 and any substance contained in dispensingchamber 405.Interface 530 connectstemperature control device 450 andthermal sensor 460 withtip interface connector 520. - The components of
tip segment 205, including dispensingchamber housing 425,temperature control device 450, andplunger 415 are at least partially enclosed bytip segment housing 215. In one embodiment consistent with the principles of the present invention,plunger 415 is sealed to the interior surface of dispensingchamber housing 425. This seal prevents contamination of any substance contained in dispensingchamber 405. For medical purposes, such a seal is desirable. This seal can be located at any point onplunger 415 or dispensingchamber housing 425. - In
limited reuse assembly 250,power source 505 provides power toactuator 515. An interface (not shown) betweenpower source 505 andactuator 515 serves as a conduit for providing power toactuator 515.Actuator 515 is connected toactuator shaft 510. When actuator 515 is a stepper motor,actuator shaft 510 is integral withactuator 515.Mechanical linkage interface 545 is connected toactuator shaft 510. In this configuration, asactuator 515 movesactuator shaft 510 upward towardneedle 210mechanical linkage interface 545 also moves upward towardneedle 210. -
Controller 305 is connected viainterface 535 to limited reuseassembly interface connecter 525. Limited reuseassembly interface connecter 525 is located on a top surface of limitedreuse assembly housing 255 adjacent tomechanical linkage interface 545. In this manner, both limited reuseassembly interface connector 525 andmechanical linkage interface 545 are adapted to be connected withtip interface connector 520 andplunger interface 420 respectively. -
Controller 305 andactuator 515 are connected by an interface (not shown). This interface (not shown) allowscontroller 305 to control the operation ofactuator 515. In addition, an interface (not shown) betweenpower source 505 andcontroller 305 allowscontroller 305 to control operation ofpower source 505. In such a case,controller 305 may control the charging and the discharging ofpower source 505 whenpower source 505 is a rechargeable battery. -
Controller 305 is typically an integrated circuit with power, input, and output pins capable of performing logic functions. In various embodiments,controller 305 is a targeted device controller. In such a case,controller 305 performs specific control functions targeted to a specific device or component, such as a temperature control device or a power supply. For example, a temperature control device controller has the basic functionality to control a temperature control device. In other embodiments,controller 305 is a microprocessor. In such a case,controller 305 is programmable so that it can function to control more than one component of the device. In other cases,controller 305 is not a programmable microprocessor, but instead is a special purpose controller configured to control different components that perform different functions. While depicted as one component,controller 305 may be made of many different components or integrated circuits. -
Tip segment 205 is adapted to mate with or attach tolimited reuse assembly 250 as previously described. In the embodiment ofFIG. 5 ,plunger interface 420 located on a bottom surface ofplunger 415 is adapted to mate withmechanical linkage interface 545 located near a top surface of limitedreuse assembly housing 255. In addition,tip interface connector 520 is adapted to connect with limited reuseassembly interface connector 525. Whentip segment 205 is connected tolimited reuse assembly 250 in this manner,actuator 515 andactuator shaft 510 are adapted to driveplunger 415 upward towardneedle 210. In addition, an interface is formed betweencontroller 305 andtemperature control device 450. A signal can pass fromcontroller 305 totemperature control device 450 throughinterface 535, limited reuseassembly interface connector 525,tip interface connector 520, andinterface 530. - In operation, when
tip segment 205 is connected tolimited reuse assembly 250,controller 305 controls the operation ofactuator 515.Actuator 515 is actuated andactuator shaft 510 is moved upward towardneedle 210. In turn,mechanical linkage interface 545, which is mated withplunger interface 420, movesplunger 415 upward towardneedle 210. A substance located in dispensingchamber 405 is then expelled throughneedle 210. - In addition,
controller 305 controls the operation oftemperature control device 450.Temperature control device 450 is adapted to heat and/or cool dispensingchamber housing 425. Since dispensingchamber housing 425 is at least partially thermally conductive, heating or cooling dispensingchamber housing 425 heats or cools a substance located in dispensingchamber 405. Temperature information can be transferred fromthermal sensor 460 tocontroller 305 via any of a number of different interface configurations. This temperature information can be used to control the operation oftemperature control device 450. Whentemperature control device 450 is a heater,controller 305 controls the amount of current that is sent totemperature control device 450. The more current sent totemperature control device 450, the hotter it gets. In such a manner,controller 305 can use a feed back loop utilizing information fromthermal sensor 460 to control the operation oftemperature control device 450. Any suitable type of control algorithm, such as a proportional integral derivative (PID) algorithm, can be used to control the operation oftemperature control device 450. -
FIG. 5 is a cross section view of a disposable tip segment for an ophthalmic medical device according to an embodiment of the present invention. InFIG. 5 ,disposable tip segment 205 includeshousing 215,needle 210,plunger 415,plunger interface 420, dispensingchamber 405, dispensingchamber housing 425,temperature control device 450,thermal sensor 460,interface 530, lockingtabs tip interface connector 520.Disposable tip segment 205 operates as a disposable injection device. - In the embodiment of
FIG. 5 ,plunger 415 is located in dispensingchamber housing 425.Dispensing chamber 405 is enclosed by dispensingchamber housing 425 andplunger 415.Plunger 415 forms a fluid seal with the interior surface of dispensingchamber housing 425.Needle 210 is fluidly coupled to dispensingchamber 405. In this manner, a substance located in dispensingchamber 405 can be contacted byplunger 415 and pushed out ofneedle 210.Temperature control device 450 is located adjacent to dispensingchamber housing 425 and at least partially surrounds dispensingchamber 405.Housing 215 forms an outer skin ondisposable tip segment 205. - In various embodiments of the present invention,
temperature control device 450 is a heating and/or a cooling device.Temperature control device 450 is in thermal contact with dispensingchamber housing 425. As such,temperature control device 450 is capable of changing the temperature of the substance in dispensingchamber 405.Interface 530 andtip interface connector 520 coupletemperature control device 450 to a limited reuse assembly. In such a case,temperature control device 450 can be powered and controlled by the limited reuse assembly. In one embodiment of the present invention,temperature control device 450 receives voltage viainterface 530 from a limited reuse assembly. Providing a positive voltage across thetemperature control device 450 causes it to produce heat. Providing a negative voltage across thetemperature control device 450 causes it to cool. - A substance to be delivered into an eye, typically a drug, is located in dispensing
chamber 405. In this manner, the substance is contacted by the inner surface of dispensingchamber housing 425 and one face ofplunger 415. Typically, dispensingchamber 405 is cylindrical in shape.Temperature control device 450 is in thermal contact with dispensingchamber housing 425. In this manner,temperature control device 450 is adapted to control the temperature of the contents of dispensingchamber 425.Thermal sensor 460 provides temperature information to assist in controlling the operation oftemperature control device 450. - In one embodiment of the present invention, the substance located in dispensing
chamber 405 is a drug that is preloaded into the dispensing chamber. In such a case,disposable tip segment 205 is appropriate as a single use consumable product. Such a disposable product can be assembled at a factory with a dosage of a drug installed. - When a drug is preloaded into dispensing
chamber 405, a set quantity of the drug can be preloaded. For example, 100 microliters of a drug can be loaded into dispensingchamber 405, and any quantity up to 100 microliters can be dispensed. In such a case, theplunger 415 can be moved a precise distance to deliver a precise dosage of drug from the dispensingchamber 405, through theneedle 210, and into an eye. This provides for flexibility of dosing and for ease of assembly. - Locking
tabs limited reuse assembly 250. Preferably,tip segment 205 is configured to be inserted into alimited reuse assembly 205 and rotated (preferably about a quarter turn) so thattip segment 205 is securely attached tolimited reuse assembly 250. In this manner, lockingtabs limited reuse assembly 250 that extend circumferentially at least a portion of the way around an interior surface of limited reuse assembly. As such,tip segment 205 is rotated and locked ontolimited reuse assembly 250. -
FIG. 6 is a top view of a sharps container according to the principles of the present invention.Sharps container 600 has anopening 610 that is configured to receive adisposable tip segment 205. As is known, a sharps container allows for the safe disposal of needles, such as those used in injection devices. When a two piece injection device, like the one described above, is used, a sharps container should be configured to receive thedisposable tip segment 205 after it is used. In such a manner, disposable tip segment can be discarded safely. -
Opening 610 is configured to receivetip segment 205. In one embodiment of the present invention, atip segment 205 is inserted intoopening 610 while still connected to alimited reuse assembly 250.Opening 610 engagestip segment 205 so thatlimited reuse assembly 250 can be rotated to disconnect it fromtip segment 205.Limited reuse assembly 250 is then removed, andtip segment 205 falls intosharps container 600. -
Opening 610 is configured so that it holdstip segment 205. As such,tip segment 205 does not rotate when an attachedlimited reuse assembly 250 is rotated. This configuration allows disengagement oftip segment 205 fromlimited reuse assembly 250. Opening 610 can be configured with any of a number of different shapes, surfaces, or protrusions that engage alimited reuse assembly 205 to hold it in place. - While the present invention is described in the context of a single-use ophthalmic drug delivery device, the present invention encompasses any medical device or injection device. Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.
Claims (12)
1. A sharps container comprising:
a cavity for receiving a device with a needle; and
an opening configured to engage the device so that the device is held in place while a reusable assembly is removed from the device.
2. The sharps container of claim 1 wherein the opening has a surface that is configured to engage a surface on the device.
3. The sharps container of claim 1 wherein the opening has a protrusion that is configured to engage the device.
4. The sharps container of claim 1 wherein the opening has a shape that is configured to engage the device.
5. The sharps container of claim 1 wherein the opening is configured to retain the device while the reusable assembly is rotated with respect to the device.
6. The sharps container of claim 1 wherein the opening is configured unlock the device from the reusable assembly.
7. A sharps container system comprising:
a disposable tip segment comprising a dispensing chamber, a needle fluidly coupled to the dispensing chamber, and a housing at least partially enclosing the dispensing chamber; and
a sharps container comprising a cavity for receiving the disposable tip segment and an opening configured to engage the disposable tip segment so that the disposable tip segment is held in place while a limited reuse assembly is removed from the disposable tip segment.
8. The sharps container system of claim 7 wherein the opening has a surface that is configured to engage a surface on the housing.
9. The sharps container system of claim 7 wherein the opening has a protrusion that is configured to engage the disposable tip segment.
10. The sharps container system of claim 7 wherein the opening has a shape that is configured to engage the disposable tip segment.
11. The sharps container system of claim 7 wherein the opening is configured to retain the device while the limited reuse assembly is rotated with respect to the disposable tip segment.
12. The sharps container of claim 7 wherein the opening is configured unlock the disposable tip segment from the reusable assembly.
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US11/833,668 Expired - Fee Related US7887517B2 (en) | 2006-05-17 | 2007-08-03 | Drug casting |
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US20080015545A1 (en) | 2008-01-17 |
MX2007005846A (en) | 2008-12-01 |
KR20070111394A (en) | 2007-11-21 |
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TW200744558A (en) | 2007-12-16 |
US8821440B2 (en) | 2014-09-02 |
JP2007307376A (en) | 2007-11-29 |
CN101073682A (en) | 2007-11-21 |
US20080021413A1 (en) | 2008-01-24 |
BRPI0702340A (en) | 2008-01-15 |
US20070270750A1 (en) | 2007-11-22 |
US20080097311A1 (en) | 2008-04-24 |
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CA2588519A1 (en) | 2007-11-17 |
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EP1857130A1 (en) | 2007-11-21 |
IL183295A0 (en) | 2007-12-03 |
US20080021419A1 (en) | 2008-01-24 |
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