US20100137980A1 - Annular Prosthesis for a Mitral Valve - Google Patents

Annular Prosthesis for a Mitral Valve Download PDF

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Publication number
US20100137980A1
US20100137980A1 US12/697,936 US69793610A US2010137980A1 US 20100137980 A1 US20100137980 A1 US 20100137980A1 US 69793610 A US69793610 A US 69793610A US 2010137980 A1 US2010137980 A1 US 2010137980A1
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United States
Prior art keywords
ring
prosthesis
height
anterior
annular
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/697,936
Inventor
Ottavio Alfieri
Francesco Maisano
Alberto Redaelli
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Edwards Lifesciences Corp
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Edwards Lifesciences Corp
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Publication date
Application filed by Edwards Lifesciences Corp filed Critical Edwards Lifesciences Corp
Priority to US12/697,936 priority Critical patent/US20100137980A1/en
Assigned to EDWARDS LIFESCIENCES CORPORATION reassignment EDWARDS LIFESCIENCES CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ALFIERI, OTTAVIO, MAISANO, FRANCESCO, REDAELLI, ALBERTO
Publication of US20100137980A1 publication Critical patent/US20100137980A1/en
Priority to US13/416,929 priority patent/US8529621B2/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445Annuloplasty rings in direct contact with the valve annulus
    • A61F2/2448D-shaped rings

Definitions

  • the present invention refers to an annular prosthesis for a mitral valve.
  • a mitral plastic surgery operation includes a series of procedures suitable to re-establish the correct functionality of the mitral valve, when it is affected by congenital or acquired pathology.
  • the remodelling of the valve annulus is one of the most frequently used maneuvers in order to complete and/or to strengthen the valve. Remodeling provides for two moments: the reduction of the annular area and the proper remodeling that is suitable to re-establish the normal geometric ratios that are found in natural valves free of pathology.
  • the first one of these maneuvers is usually carried out with the aid of a prosthesis that is appropriately sutured to the natural annulus.
  • the prostheses for annuloplastic surgery available on the market are of two types.
  • Flexible annular prostheses made of various materials, that allow a “linear” reduction of the annular circumference
  • rigid and semi-rigid annular prostheses made of various materials, that allow the “linear” reduction of the annular circumference and a geometric remodeling so as to re-establish the physiological systolic shape of the annulus.
  • semi-rigid prostheses they additionally allow a minimum deformation in order to allow the prosthesis to follow the deformations of the annulus-during the cardiac stages.
  • All the rigid and semi-rigid annular prostheses have a kidney-like or coupled D shape, with an anterior half-ring, rectilinear in first approximation, that gets sutured in correspondence of the joining of the anterior valve leaflet and a curved posterior half-ring that is sutured in correspondence of the joining of the posterior valve leaflet.
  • the shape of the annular prostheses at issue reproduces the configuration of the valve annulus during the ventricular systole, and therefore in the stage of the valve closing.
  • the ratio between the minor axis and the major axis is approximately 3 ⁇ 4 in all the models currently on the market, since this reproduces the normal anatomical ratios.
  • undersizing of mitral valve annuloplasty has been introduced. This procedure is proposed in case of mitral insufficiency due to a reduced movement of the leaflets, as in the case of ischemic mitral valve or dilated cardiomyopathy.
  • the undersizing consists in using a ring smaller than necessary, though still maintaining the ratio of approximately 3 ⁇ 4, and it is carried out in order to bring the base of the anterior leaflet even closer to the posterior leaflet in order to increase the coaptation surface (closure).
  • the object of the present invention is to provide an annular prosthesis for mitral valve that can meet the different requirements that have been noticed.
  • annular prosthesis for a mitral valve made up of a posterior half-ring and an anterior half-ring that are coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis.
  • the ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than 3 ⁇ 4.
  • FIG. 1 shows an annular prosthesis for a mitral valve according to the known art
  • FIG. 2 shows a first embodiment of an annular prosthesis for a mitral valve according to the present invention
  • FIG. 3 shows a second embodiment of an annular prosthesis for a mitral valve according to the present invention.
  • FIG. 4 shows a third embodiment of an annular prosthesis for a mitral valve according to the present invention.
  • FIG. 1 a prosthesis for an annular mitral valve according to the known art is shown. It has a kidney-like or D-shape, and it is made up of an anterior half-ring 1 rectilinear in first approximation, that is sutured in correspondence of the joining of the anterior valve leaflet 1 and a curved posterior half-ring 2 that is sutured in correspondence of the joining of the posterior valve leaflet.
  • the posterior half-ring 2 and anterior half-ring 1 are coupled at two points 5 and 6 located on a transverse plane 3 that define a maximum width section of the prosthesis.
  • a longitudinal plane 4 is defined that intersects the prosthesis at the points 7 and 8 , and is arranged perpendicular to the transverse plane 3 and equidistant from the coupling points 5 and 6 .
  • the posterior half-ring 2 is thus subdivided in a first lateral zone (left) 9 located between the points 5 and 7 , and a second lateral zone (right) 10 located between the points 6 and 7 .
  • the intersection points 5 , 6 and 7 , 8 of the prosthesis, respectively, with the planes 3 and 4 define the terms for the calculation of the dimensions of the prosthesis.
  • the ratio between the distance between the points 7 and 8 herein also defined as the height of the prosthesis, and the distance between the points 5 and 6 , herein also defined as the width of the prosthesis, is typically equal to 3 ⁇ 4.
  • FIG. 2 a first embodiment of an annular prosthesis for a mitral valve according to the present invention is shown. It has substantially the same shape as the one rendered in FIG. 1 , but the ratio between the height and the width of the prosthesis is lower than 3 ⁇ 4 (0.75), for instance equal to 2.5/4 (0.625) or equal to 2/4 (0.5).
  • the dimension of the transverse width of the prosthesis is meant; it represents the clinical parameter on the basis of which the prosthesis is selected in each single clinical case in examination, and it is also the identifying parameter for the prosthesis.
  • the lower ratio as compared with the prostheses currently used for annuloplastic surgery, allows its use in selected cases of pathologies that are not treatable in an adequate way with conventional prostheses.
  • the lower ratios in this case have the function to treat pathologies characterized by reduced movement of the leaflets with tethering (stretching towards the cardiac apex) symmetrical (as regards each leaflet) with medium or serious proportions.
  • the reduction of the ratio confers the prosthesis a more “squeezed” shape that allows a better apposition of the leaflets in selected cases.
  • the leaflets stretch toward the cardiac apex and the apposition is thus lacking at the central level.
  • the anterior half-ring 1 (the base for the implant of the front leaflet) is anatomically fixed and not modifiable, and therefore, sizing should not be applied to this structure, that is, to the width of the prosthesis.
  • the maintaining of a normal fore width of the prosthesis, associated with the reduction of the height allows an undersizing that is less inclined to deformation of the fore leaflet, therefore reducing the risk of residual insufficiency.
  • FIG. 3 a second embodiment of an annular prosthesis for a mitral valve according to the present invention is shown.
  • the natural ratio height/width of 3 ⁇ 4 is maintained in order to define the curving radii of the two lateral parts of the anterior half-ring.
  • the distance between the posterior half-ring 2 and the front half-ring 1 is reduced, with the aim of obtaining a height/width ratio lower than 3 ⁇ 4.
  • the central zone of the posterior half-ring 2 therefore takes a configuration that recalls the dog bone or gull wing shape and increases the coaptation at the central level by limiting the annular reduction at level of the commissure.
  • FIG. 4 a third embodiment of an annular prosthesis for a mitral valve according to the present invention is shown.
  • the curving radius of one of the lateral zones, for instance the second lateral zone (right) 10 is increased so as to induce a selective increase of the competence in correspondence of the valve sector with reduced mobility of the leaflets (bad asymmetric apposition of the leaflets as in ischemic pathology).
  • one part of the prosthesis for instance the first lateral zone (left) 9
  • the second lateral zone (right) 10 gets a sized configuration.
  • the distance between the middle point of the first lateral zone (left) 9 and the longitudinal plane 4 is greater than the distance between the middle point of the second lateral zone (right) 10 and the longitudinal plane
  • the prosthesis can be made of an inert material that is highly tolerated by the human organism and can have a resistance that is appropriate to the use and that can substantially maintain the shape given to it.

Abstract

An annular prosthesis for a mitral valve that may include a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than ¾.

Description

    RELATED APPLICATIONS
  • The present application is a continuation of U.S. application Ser. No. 10/742,454, filed Dec. 18, 2003, under the same title, which claims priority to U.S. application Ser. No. 10/144,932, filed May 15, 2002, under the same title, which claims priority under 35 U.S.C. §119 to Italian Application No. MI 2001A 001012, filed May 17, 2001.
  • FIELD OF THE INVENTION
  • The present invention refers to an annular prosthesis for a mitral valve.
  • BACKGROUND OF THE INVENTION
  • A mitral plastic surgery operation includes a series of procedures suitable to re-establish the correct functionality of the mitral valve, when it is affected by congenital or acquired pathology. Among these procedures, the remodelling of the valve annulus is one of the most frequently used maneuvers in order to complete and/or to strengthen the valve. Remodeling provides for two moments: the reduction of the annular area and the proper remodeling that is suitable to re-establish the normal geometric ratios that are found in natural valves free of pathology. The first one of these maneuvers is usually carried out with the aid of a prosthesis that is appropriately sutured to the natural annulus. The prostheses for annuloplastic surgery available on the market are of two types. Flexible annular prostheses, made of various materials, that allow a “linear” reduction of the annular circumference, and rigid and semi-rigid annular prostheses made of various materials, that allow the “linear” reduction of the annular circumference and a geometric remodeling so as to re-establish the physiological systolic shape of the annulus. In the case of semi-rigid prostheses, they additionally allow a minimum deformation in order to allow the prosthesis to follow the deformations of the annulus-during the cardiac stages.
  • All the rigid and semi-rigid annular prostheses have a kidney-like or coupled D shape, with an anterior half-ring, rectilinear in first approximation, that gets sutured in correspondence of the joining of the anterior valve leaflet and a curved posterior half-ring that is sutured in correspondence of the joining of the posterior valve leaflet. The shape of the annular prostheses at issue reproduces the configuration of the valve annulus during the ventricular systole, and therefore in the stage of the valve closing. The ratio between the minor axis and the major axis is approximately ¾ in all the models currently on the market, since this reproduces the normal anatomical ratios.
  • Recently the concept of undersizing of mitral valve annuloplasty has been introduced. This procedure is proposed in case of mitral insufficiency due to a reduced movement of the leaflets, as in the case of ischemic mitral valve or dilated cardiomyopathy. The undersizing consists in using a ring smaller than necessary, though still maintaining the ratio of approximately ¾, and it is carried out in order to bring the base of the anterior leaflet even closer to the posterior leaflet in order to increase the coaptation surface (closure).
  • The Applicants noticed that in certain pathological conditions, there is a need to modify such ratio in order to make the operation of reconstruction of the mitral valve more effective: for instance in order to bring the valve leaflets closer to each other in the case of anatomical or functional tissue deficiency of one or both leaflets. In addition, it has also been observed that anatomical variation that do not correspond to the ratios reported above are frequent in nature.
  • In view of the state of the art described herein, the object of the present invention is to provide an annular prosthesis for mitral valve that can meet the different requirements that have been noticed.
  • SUMMARY OF THE INVENTION
  • According to present the invention, these and other objects have been attained by means of an annular prosthesis for a mitral valve made up of a posterior half-ring and an anterior half-ring that are coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than ¾.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • The characteristics and the advantages of the present invention will become evident from the following detailed description of an embodiment thereof, which is illustrated by a non-limiting example in the enclosed drawings, in which:
  • FIG. 1 shows an annular prosthesis for a mitral valve according to the known art;
  • FIG. 2 shows a first embodiment of an annular prosthesis for a mitral valve according to the present invention;
  • FIG. 3 shows a second embodiment of an annular prosthesis for a mitral valve according to the present invention; and
  • FIG. 4 shows a third embodiment of an annular prosthesis for a mitral valve according to the present invention.
  • DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • In FIG. 1 a prosthesis for an annular mitral valve according to the known art is shown. It has a kidney-like or D-shape, and it is made up of an anterior half-ring 1 rectilinear in first approximation, that is sutured in correspondence of the joining of the anterior valve leaflet 1 and a curved posterior half-ring 2 that is sutured in correspondence of the joining of the posterior valve leaflet. The posterior half-ring 2 and anterior half-ring 1 are coupled at two points 5 and 6 located on a transverse plane 3 that define a maximum width section of the prosthesis. In addition a longitudinal plane 4 is defined that intersects the prosthesis at the points 7 and 8, and is arranged perpendicular to the transverse plane 3 and equidistant from the coupling points 5 and 6. The posterior half-ring 2 is thus subdivided in a first lateral zone (left) 9 located between the points 5 and 7, and a second lateral zone (right) 10 located between the points 6 and 7. The intersection points 5, 6 and 7, 8 of the prosthesis, respectively, with the planes 3 and 4 define the terms for the calculation of the dimensions of the prosthesis. According to the known art, the ratio between the distance between the points 7 and 8, herein also defined as the height of the prosthesis, and the distance between the points 5 and 6, herein also defined as the width of the prosthesis, is typically equal to ¾.
  • In FIG. 2 a first embodiment of an annular prosthesis for a mitral valve according to the present invention is shown. It has substantially the same shape as the one rendered in FIG. 1, but the ratio between the height and the width of the prosthesis is lower than ¾ (0.75), for instance equal to 2.5/4 (0.625) or equal to 2/4 (0.5).
  • For every size of prosthesis two or more reduced ratios can therefore be provided. By size, the dimension of the transverse width of the prosthesis is meant; it represents the clinical parameter on the basis of which the prosthesis is selected in each single clinical case in examination, and it is also the identifying parameter for the prosthesis.
  • The lower ratio, as compared with the prostheses currently used for annuloplastic surgery, allows its use in selected cases of pathologies that are not treatable in an adequate way with conventional prostheses.
  • The lower ratios in this case have the function to treat pathologies characterized by reduced movement of the leaflets with tethering (stretching towards the cardiac apex) symmetrical (as regards each leaflet) with medium or serious proportions. The reduction of the ratio confers the prosthesis a more “squeezed” shape that allows a better apposition of the leaflets in selected cases. For instance, in the dilated cardiomyopathy, when the expansion of the left ventricle determines a lateral movement and toward the apex of the papillary muscles, the leaflets stretch toward the cardiac apex and the apposition is thus lacking at the central level. Possible sizing, in addition, must respect an anatomical requirement: the anterior half-ring 1 (the base for the implant of the front leaflet) is anatomically fixed and not modifiable, and therefore, sizing should not be applied to this structure, that is, to the width of the prosthesis. The maintaining of a normal fore width of the prosthesis, associated with the reduction of the height allows an undersizing that is less inclined to deformation of the fore leaflet, therefore reducing the risk of residual insufficiency.
  • In FIG. 3 a second embodiment of an annular prosthesis for a mitral valve according to the present invention is shown. In this case the natural ratio height/width of ¾ is maintained in order to define the curving radii of the two lateral parts of the anterior half-ring. In the central zone, in proximity of the point 7, the distance between the posterior half-ring 2 and the front half-ring 1 is reduced, with the aim of obtaining a height/width ratio lower than ¾. The central zone of the posterior half-ring 2 therefore takes a configuration that recalls the dog bone or gull wing shape and increases the coaptation at the central level by limiting the annular reduction at level of the commissure.
  • In some extreme cases, it could be useful to make the distance between the two half-rings in the central zone equal to zero, in order to obtain an eight-shape configuration, as seen in phantom in FIG. 3, in order to improve the coaptation at the central level. This remodeling simulates the double orifice operation, in which the leaflets are joined at the center of the valve in order to force the central coaptation. This prosthesis could also be used with this type of technique in order to reduce the stress on the suture and in order to minimize the reduction of the valve area.
  • In FIG. 4 a third embodiment of an annular prosthesis for a mitral valve according to the present invention is shown. In this embodiment the curving radius of one of the lateral zones, for instance the second lateral zone (right) 10, is increased so as to induce a selective increase of the competence in correspondence of the valve sector with reduced mobility of the leaflets (bad asymmetric apposition of the leaflets as in ischemic pathology). It is thus obtained that one part of the prosthesis, for instance the first lateral zone (left) 9, maintains a configuration substantially similar to the traditional prosthesis and one part, for instance the second lateral zone (right) 10, gets a sized configuration. In other words the distance between the middle point of the first lateral zone (left) 9 and the longitudinal plane 4 is greater than the distance between the middle point of the second lateral zone (right) 10 and the longitudinal plane
  • The prosthesis, according to the present invention, can be made of an inert material that is highly tolerated by the human organism and can have a resistance that is appropriate to the use and that can substantially maintain the shape given to it.

Claims (3)

1. An annular prosthetic ring for a mitral valve comprising:
a curved posterior section contiguous with a generally rectilinear anterior section and together forming a generally D-shaped periphery oriented about a central flow axis, wherein in plan view as seen along the flow axis the ring has an anterior axis parallel to the generally rectilinear anterior section, said anterior axis defining the maximum width of the ring, and an axis transverse to the anterior axis that defines the height of the ring and wherein the maximum width of the ring is maintained equal to the maximum width of conventional rings but the height of the ring is substantially less than the height of conventional rings.
2. The annular prosthetic ring of claim wherein the height of the ring is such that the ratio of the height of the ring to the maximum width of the ring is less than about 0.625.
3. The annular prosthetic ring of claim 3 wherein the ratio of the height of the ring to the maximum width of the ring is less than about 0.5.
US12/697,936 2001-05-17 2010-02-01 Annular Prosthesis for a Mitral Valve Abandoned US20100137980A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/697,936 US20100137980A1 (en) 2001-05-17 2010-02-01 Annular Prosthesis for a Mitral Valve
US13/416,929 US8529621B2 (en) 2001-05-17 2012-03-09 Methods of repairing an abnormal mitral valve

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT2001MI001012A ITMI20011012A1 (en) 2001-05-17 2001-05-17 ANNULAR PROSTHESIS FOR MITRAL VALVE
ITMI2001A001012 2001-05-17
US10/144,932 US6726717B2 (en) 2001-05-17 2002-05-15 Annular prosthesis for mitral valve
US10/742,454 US7674286B2 (en) 2001-05-17 2003-12-18 Annular prosthesis for a mitral valve
US12/697,936 US20100137980A1 (en) 2001-05-17 2010-02-01 Annular Prosthesis for a Mitral Valve

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/742,454 Continuation US7674286B2 (en) 2001-05-17 2003-12-18 Annular prosthesis for a mitral valve

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/416,929 Continuation US8529621B2 (en) 2001-05-17 2012-03-09 Methods of repairing an abnormal mitral valve

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US20100137980A1 true US20100137980A1 (en) 2010-06-03

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Application Number Title Priority Date Filing Date
US10/144,932 Expired - Lifetime US6726717B2 (en) 2001-05-17 2002-05-15 Annular prosthesis for mitral valve
US10/742,454 Active 2024-06-07 US7674286B2 (en) 2001-05-17 2003-12-18 Annular prosthesis for a mitral valve
US12/697,936 Abandoned US20100137980A1 (en) 2001-05-17 2010-02-01 Annular Prosthesis for a Mitral Valve
US13/416,929 Expired - Lifetime US8529621B2 (en) 2001-05-17 2012-03-09 Methods of repairing an abnormal mitral valve

Family Applications Before (2)

Application Number Title Priority Date Filing Date
US10/144,932 Expired - Lifetime US6726717B2 (en) 2001-05-17 2002-05-15 Annular prosthesis for mitral valve
US10/742,454 Active 2024-06-07 US7674286B2 (en) 2001-05-17 2003-12-18 Annular prosthesis for a mitral valve

Family Applications After (1)

Application Number Title Priority Date Filing Date
US13/416,929 Expired - Lifetime US8529621B2 (en) 2001-05-17 2012-03-09 Methods of repairing an abnormal mitral valve

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US (4) US6726717B2 (en)
EP (1) EP1258232B1 (en)
AT (1) ATE419808T1 (en)
DE (1) DE60230697D1 (en)
IT (1) ITMI20011012A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9814574B2 (en) 2010-09-30 2017-11-14 BioStable Science & Engineering, Inc. Non-axisymmetric aortic valve devices

Families Citing this family (255)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406420B1 (en) * 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US7883539B2 (en) 1997-01-02 2011-02-08 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US6050936A (en) 1997-01-02 2000-04-18 Myocor, Inc. Heart wall tension reduction apparatus
US6332893B1 (en) * 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
US6260552B1 (en) 1998-07-29 2001-07-17 Myocor, Inc. Transventricular implant tools and devices
US6736845B2 (en) 1999-01-26 2004-05-18 Edwards Lifesciences Corporation Holder for flexible heart valve
US6797002B2 (en) * 2000-02-02 2004-09-28 Paul A. Spence Heart valve repair apparatus and methods
US6537198B1 (en) * 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US7510572B2 (en) * 2000-09-12 2009-03-31 Shlomo Gabbay Implantation system for delivery of a heart valve prosthesis
US6723038B1 (en) * 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6616684B1 (en) * 2000-10-06 2003-09-09 Myocor, Inc. Endovascular splinting devices and methods
US6602286B1 (en) * 2000-10-26 2003-08-05 Ernst Peter Strecker Implantable valve system
US6955689B2 (en) * 2001-03-15 2005-10-18 Medtronic, Inc. Annuloplasty band and method
US6786924B2 (en) * 2001-03-15 2004-09-07 Medtronic, Inc. Annuloplasty band and method
US7935145B2 (en) * 2001-05-17 2011-05-03 Edwards Lifesciences Corporation Annuloplasty ring for ischemic mitral valve insuffuciency
ITMI20011012A1 (en) * 2001-05-17 2002-11-17 Ottavio Alfieri ANNULAR PROSTHESIS FOR MITRAL VALVE
US6858039B2 (en) 2002-07-08 2005-02-22 Edwards Lifesciences Corporation Mitral valve annuloplasty ring having a posterior bow
US7367991B2 (en) * 2001-08-28 2008-05-06 Edwards Lifesciences Corporation Conformal tricuspid annuloplasty ring and template
US6908482B2 (en) 2001-08-28 2005-06-21 Edwards Lifesciences Corporation Three-dimensional annuloplasty ring and template
US20080154359A1 (en) * 2001-11-01 2008-06-26 Salgo Ivan S Non-planar cardiac vascular support prosthesis
US6805710B2 (en) * 2001-11-13 2004-10-19 Edwards Lifesciences Corporation Mitral valve annuloplasty ring for molding left ventricle geometry
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7118595B2 (en) * 2002-03-18 2006-10-10 Medtronic, Inc. Flexible annuloplasty prosthesis and holder
US6719786B2 (en) * 2002-03-18 2004-04-13 Medtronic, Inc. Flexible annuloplasty prosthesis and holder
US7007698B2 (en) * 2002-04-03 2006-03-07 Boston Scientific Corporation Body lumen closure
US6752828B2 (en) 2002-04-03 2004-06-22 Scimed Life Systems, Inc. Artificial valve
US20030233022A1 (en) * 2002-06-12 2003-12-18 Vidlund Robert M. Devices and methods for heart valve treatment
US7608103B2 (en) * 2002-07-08 2009-10-27 Edwards Lifesciences Corporation Mitral valve annuloplasty ring having a posterior bow
WO2004037128A1 (en) 2002-10-24 2004-05-06 Boston Scientific Limited Venous valve apparatus and method
US7112219B2 (en) * 2002-11-12 2006-09-26 Myocor, Inc. Devices and methods for heart valve treatment
US7247134B2 (en) * 2002-11-12 2007-07-24 Myocor, Inc. Devices and methods for heart valve treatment
US6945957B2 (en) 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
DE10301023A1 (en) 2003-01-13 2004-07-22 Medos Medizintechnik Ag Implant, in particular ring for heart valve, designed in curved and asymmetric shape
US20050004665A1 (en) * 2003-07-02 2005-01-06 Lishan Aklog Annuloplasty rings and methods for repairing cardiac valves
US8052751B2 (en) * 2003-07-02 2011-11-08 Flexcor, Inc. Annuloplasty rings for repairing cardiac valves
CA2539459C (en) * 2003-10-03 2012-04-24 Edwards Lifesciences Corporation Annuloplasty rings for repair of abnormal mitral valves
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7854761B2 (en) 2003-12-19 2010-12-21 Boston Scientific Scimed, Inc. Methods for venous valve replacement with a catheter
EP2433591B1 (en) * 2004-05-14 2016-04-27 St. Jude Medical, Inc. Apparatus for holding an annuloplasty ring
US20050256568A1 (en) * 2004-05-14 2005-11-17 St. Jude Medical, Inc. C-shaped heart valve prostheses
US7938856B2 (en) * 2004-05-14 2011-05-10 St. Jude Medical, Inc. Heart valve annuloplasty prosthesis sewing cuffs and methods of making same
US7452376B2 (en) * 2004-05-14 2008-11-18 St. Jude Medical, Inc. Flexible, non-planar annuloplasty rings
US20050278022A1 (en) * 2004-06-14 2005-12-15 St. Jude Medical, Inc. Annuloplasty prostheses with improved anchoring structures, and related methods
DE502004005968D1 (en) * 2004-06-29 2008-03-06 Sievers Hans Hinrich Ring prosthesis for annuloplasty
US7758638B2 (en) 2004-07-13 2010-07-20 Ats Medical, Inc. Implant with an annular base
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US20060173490A1 (en) 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US20060206203A1 (en) * 2005-03-10 2006-09-14 Jun Yang Valvular support prosthesis
US8608797B2 (en) 2005-03-17 2013-12-17 Valtech Cardio Ltd. Mitral valve treatment techniques
US7575595B2 (en) 2005-03-23 2009-08-18 Edwards Lifesciences Corporation Annuloplasty ring and holder combination
US7842085B2 (en) * 2005-03-23 2010-11-30 Vaso Adzich Annuloplasty ring and holder combination
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US20060247491A1 (en) * 2005-04-27 2006-11-02 Vidlund Robert M Devices and methods for heart valve treatment
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US8685083B2 (en) * 2005-06-27 2014-04-01 Edwards Lifesciences Corporation Apparatus, system, and method for treatment of posterior leaflet prolapse
US8951285B2 (en) 2005-07-05 2015-02-10 Mitralign, Inc. Tissue anchor, anchoring system and methods of using the same
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
US20070100441A1 (en) * 2005-10-26 2007-05-03 St. Jude Medical, Inc. Saddle-shaped mitral valve annuloplasty prostheses with asymmetry, and related methods
US8764820B2 (en) 2005-11-16 2014-07-01 Edwards Lifesciences Corporation Transapical heart valve delivery system and method
US8568473B2 (en) 2005-12-15 2013-10-29 Georgia Tech Research Corporation Systems and methods for enabling heart valve replacement
EP1968492A2 (en) 2005-12-15 2008-09-17 Georgia Technology Research Corporation Systems and methods to control the dimension of a heart valve
US9125742B2 (en) 2005-12-15 2015-09-08 Georgia Tech Research Foundation Papillary muscle position control devices, systems, and methods
US7799038B2 (en) 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
CA2677968C (en) 2006-05-15 2014-07-08 Enovacor Aps A system and a method for altering the geometry of the heart
WO2007143077A2 (en) * 2006-06-02 2007-12-13 Medtronic, Inc. Annuloplasty ring and method
EP2032079B1 (en) 2006-06-02 2015-08-12 Medtronic, Inc. Annuloplasty prosthesis with in vivo shape identification
US20080058924A1 (en) * 2006-09-01 2008-03-06 Aaron Ingle Saddle-shaped annuloplasty ring
US8163011B2 (en) 2006-10-06 2012-04-24 BioStable Science & Engineering, Inc. Intra-annular mounting frame for aortic valve repair
US7879087B2 (en) * 2006-10-06 2011-02-01 Edwards Lifesciences Corporation Mitral and tricuspid annuloplasty rings
US11259924B2 (en) 2006-12-05 2022-03-01 Valtech Cardio Ltd. Implantation of repair devices in the heart
US9883943B2 (en) 2006-12-05 2018-02-06 Valtech Cardio, Ltd. Implantation of repair devices in the heart
WO2010004546A1 (en) 2008-06-16 2010-01-14 Valtech Cardio, Ltd. Annuloplasty devices and methods of delivery therefor
JP2010511469A (en) 2006-12-05 2010-04-15 バルテック カーディオ,リミティド Segmented ring placement
US8133270B2 (en) 2007-01-08 2012-03-13 California Institute Of Technology In-situ formation of a valve
JP5313928B2 (en) 2007-02-05 2013-10-09 ボストン サイエンティフィック リミテッド Percutaneous valves and systems
WO2008098226A1 (en) * 2007-02-09 2008-08-14 Edwards Lifesciences Corporation Progressively sized annuloplasty rings
US11660190B2 (en) 2007-03-13 2023-05-30 Edwards Lifesciences Corporation Tissue anchors, systems and methods, and devices
US8529620B2 (en) * 2007-05-01 2013-09-10 Ottavio Alfieri Inwardly-bowed tricuspid annuloplasty ring
US8828079B2 (en) 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
CN103393485B (en) 2007-09-07 2016-08-10 爱德华兹生命科学公司 For carrying the travel(l)ing rest of annuloplasty ring
DE102007043830A1 (en) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Heart valve stent
US8784483B2 (en) 2007-11-19 2014-07-22 The Cleveland Clinic Foundation Apparatus and method for treating a regurgitant heart valve
US8216303B2 (en) * 2007-11-19 2012-07-10 The Cleveland Clinic Foundation Apparatus and method for treating a regurgitant heart valve
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US7993395B2 (en) * 2008-01-25 2011-08-09 Medtronic, Inc. Set of annuloplasty devices with varying anterior-posterior ratios and related methods
US8382829B1 (en) 2008-03-10 2013-02-26 Mitralign, Inc. Method to reduce mitral regurgitation by cinching the commissure of the mitral valve
US20100121435A1 (en) * 2008-04-16 2010-05-13 Cardiovascular Technologies, Llc Percutaneous transvalvular intrannular band for mitral valve repair
US20100121437A1 (en) 2008-04-16 2010-05-13 Cardiovascular Technologies, Llc Transvalvular intraannular band and chordae cutting for ischemic and dilated cardiomyopathy
US11083579B2 (en) 2008-04-16 2021-08-10 Heart Repair Technologies, Inc. Transvalvular intraanular band and chordae cutting for ischemic and dilated cardiomyopathy
US20100131057A1 (en) * 2008-04-16 2010-05-27 Cardiovascular Technologies, Llc Transvalvular intraannular band for aortic valve repair
US8262725B2 (en) * 2008-04-16 2012-09-11 Cardiovascular Technologies, Llc Transvalvular intraannular band for valve repair
US10456259B2 (en) 2008-04-16 2019-10-29 Heart Repair Technologies, Inc. Transvalvular intraannular band for mitral valve repair
US11013599B2 (en) 2008-04-16 2021-05-25 Heart Repair Technologies, Inc. Percutaneous transvalvular intraannular band for mitral valve repair
US8152844B2 (en) 2008-05-09 2012-04-10 Edwards Lifesciences Corporation Quick-release annuloplasty ring holder
US20090287303A1 (en) 2008-05-13 2009-11-19 Edwards Lifesciences Corporation Physiologically harmonized tricuspid annuloplasty ring
US8287591B2 (en) * 2008-09-19 2012-10-16 Edwards Lifesciences Corporation Transformable annuloplasty ring configured to receive a percutaneous prosthetic heart valve implantation
US9314335B2 (en) * 2008-09-19 2016-04-19 Edwards Lifesciences Corporation Prosthetic heart valve configured to receive a percutaneous prosthetic heart valve implantation
US9375310B2 (en) 2012-12-31 2016-06-28 Edwards Lifesciences Corporation Surgical heart valves adapted for post-implant expansion
CN102292053A (en) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 Heart valve
WO2010040009A1 (en) 2008-10-01 2010-04-08 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
WO2010073246A2 (en) 2008-12-22 2010-07-01 Valtech Cardio, Ltd. Adjustable annuloplasty devices and adjustment mechanisms therefor
US10517719B2 (en) 2008-12-22 2019-12-31 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US8545553B2 (en) 2009-05-04 2013-10-01 Valtech Cardio, Ltd. Over-wire rotation tool
US8940044B2 (en) 2011-06-23 2015-01-27 Valtech Cardio, Ltd. Closure element for use with an annuloplasty structure
US8715342B2 (en) 2009-05-07 2014-05-06 Valtech Cardio, Ltd. Annuloplasty ring with intra-ring anchoring
US8241351B2 (en) * 2008-12-22 2012-08-14 Valtech Cardio, Ltd. Adjustable partial annuloplasty ring and mechanism therefor
US9011530B2 (en) 2008-12-22 2015-04-21 Valtech Cardio, Ltd. Partially-adjustable annuloplasty structure
US8808368B2 (en) 2008-12-22 2014-08-19 Valtech Cardio, Ltd. Implantation of repair chords in the heart
US8147542B2 (en) 2008-12-22 2012-04-03 Valtech Cardio, Ltd. Adjustable repair chords and spool mechanism therefor
US8926697B2 (en) 2011-06-23 2015-01-06 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US8353956B2 (en) * 2009-02-17 2013-01-15 Valtech Cardio, Ltd. Actively-engageable movement-restriction mechanism for use with an annuloplasty structure
US9078751B2 (en) * 2009-03-17 2015-07-14 Mitrassist Medical Ltd. Heart valve prosthesis with collapsible valve and method of delivery thereof
EP4119098A1 (en) 2009-04-15 2023-01-18 Edwards Lifesciences CardiAQ LLC Vascular implant and delivery system
WO2013069019A2 (en) 2011-11-08 2013-05-16 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US9968452B2 (en) 2009-05-04 2018-05-15 Valtech Cardio, Ltd. Annuloplasty ring delivery cathethers
US8523881B2 (en) 2010-07-26 2013-09-03 Valtech Cardio, Ltd. Multiple anchor delivery tool
US8449466B2 (en) 2009-05-28 2013-05-28 Edwards Lifesciences Corporation System and method for locating medical devices in vivo using ultrasound Doppler mode
US8439970B2 (en) 2009-07-14 2013-05-14 Edwards Lifesciences Corporation Transapical delivery system for heart valves
US8277502B2 (en) * 2009-10-29 2012-10-02 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US10098737B2 (en) 2009-10-29 2018-10-16 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US9180007B2 (en) 2009-10-29 2015-11-10 Valtech Cardio, Ltd. Apparatus and method for guide-wire based advancement of an adjustable implant
US9011520B2 (en) 2009-10-29 2015-04-21 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US8690939B2 (en) 2009-10-29 2014-04-08 Valtech Cardio, Ltd. Method for guide-wire based advancement of a rotation assembly
EP2506777B1 (en) 2009-12-02 2020-11-25 Valtech Cardio, Ltd. Combination of spool assembly coupled to a helical anchor and delivery tool for implantation thereof
AU2010328106A1 (en) 2009-12-08 2012-07-05 Avalon Medical Ltd. Device and system for transcatheter mitral valve replacement
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
US20110160849A1 (en) * 2009-12-22 2011-06-30 Edwards Lifesciences Corporation Bimodal tricuspid annuloplasty ring
US8449608B2 (en) * 2010-01-22 2013-05-28 Edwards Lifesciences Corporation Tricuspid ring
US10058323B2 (en) 2010-01-22 2018-08-28 4 Tech Inc. Tricuspid valve repair using tension
US8475525B2 (en) 2010-01-22 2013-07-02 4Tech Inc. Tricuspid valve repair using tension
US9307980B2 (en) 2010-01-22 2016-04-12 4Tech Inc. Tricuspid valve repair using tension
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US8790394B2 (en) 2010-05-24 2014-07-29 Valtech Cardio, Ltd. Adjustable artificial chordeae tendineae with suture loops
US11653910B2 (en) 2010-07-21 2023-05-23 Cardiovalve Ltd. Helical anchor implantation
US10524911B2 (en) 2010-08-24 2020-01-07 Edwards Lifesciences Corporation Flexible annuloplasty ring with select control points
BR112013007494B1 (en) 2010-08-31 2020-11-10 Edwards Lifesciences Corporation prosthetic tricuspid annuloplasty ring
EP2621408B1 (en) * 2010-09-30 2016-04-20 Biostable Science&Engineering Inc. Aortic valve devices
WO2012068541A2 (en) 2010-11-18 2012-05-24 Pavilion Medical Innovations Tissue restraining devices and methods of use
US9198756B2 (en) 2010-11-18 2015-12-01 Pavilion Medical Innovations, Llc Tissue restraining devices and methods of use
US8932350B2 (en) 2010-11-30 2015-01-13 Edwards Lifesciences Corporation Reduced dehiscence annuloplasty ring
US8888843B2 (en) 2011-01-28 2014-11-18 Middle Peak Medical, Inc. Device, system, and method for transcatheter treatment of valve regurgitation
US8845717B2 (en) 2011-01-28 2014-09-30 Middle Park Medical, Inc. Coaptation enhancement implant, system, and method
US9381082B2 (en) 2011-04-22 2016-07-05 Edwards Lifesciences Corporation Devices, systems and methods for accurate positioning of a prosthetic valve
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US10792152B2 (en) 2011-06-23 2020-10-06 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US9918840B2 (en) 2011-06-23 2018-03-20 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
CA3040390C (en) 2011-08-11 2022-03-15 Tendyne Holdings, Inc. Improvements for prosthetic valves and related inventions
US8920493B2 (en) 2011-09-16 2014-12-30 St. Jude Medical, Cardiology Division, Inc. Systems and methods for holding annuloplasty rings
US8858623B2 (en) 2011-11-04 2014-10-14 Valtech Cardio, Ltd. Implant having multiple rotational assemblies
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
CA2885354A1 (en) 2012-09-29 2014-04-03 Mitralign, Inc. Plication lock delivery system and method of use thereof
EP3517052A1 (en) 2012-10-23 2019-07-31 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US10376266B2 (en) 2012-10-23 2019-08-13 Valtech Cardio, Ltd. Percutaneous tissue anchor techniques
US9730793B2 (en) 2012-12-06 2017-08-15 Valtech Cardio, Ltd. Techniques for guide-wire based advancement of a tool
US10543085B2 (en) 2012-12-31 2020-01-28 Edwards Lifesciences Corporation One-piece heart valve stents adapted for post-implant expansion
US9788948B2 (en) 2013-01-09 2017-10-17 4 Tech Inc. Soft tissue anchors and implantation techniques
US9681952B2 (en) 2013-01-24 2017-06-20 Mitraltech Ltd. Anchoring of prosthetic valve supports
WO2014134183A1 (en) 2013-02-26 2014-09-04 Mitralign, Inc. Devices and methods for percutaneous tricuspid valve repair
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9687346B2 (en) 2013-03-14 2017-06-27 Edwards Lifesciences Corporation Multi-stranded heat set annuloplasty rings
CN105208978B (en) 2013-03-14 2016-12-07 4科技有限公司 There is the support of tether interface
US10449333B2 (en) 2013-03-14 2019-10-22 Valtech Cardio, Ltd. Guidewire feeder
US9744037B2 (en) 2013-03-15 2017-08-29 California Institute Of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US10149757B2 (en) 2013-03-15 2018-12-11 Edwards Lifesciences Corporation System and method for transaortic delivery of a prosthetic heart valve
EP2968847B1 (en) 2013-03-15 2023-03-08 Edwards Lifesciences Corporation Translation catheter systems
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US10463489B2 (en) 2013-04-02 2019-11-05 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US11224510B2 (en) 2013-04-02 2022-01-18 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10478293B2 (en) 2013-04-04 2019-11-19 Tendyne Holdings, Inc. Retrieval and repositioning system for prosthetic heart valve
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
CA2914856C (en) 2013-06-25 2021-03-09 Chad Perrin Thrombus management and structural compliance features for prosthetic heart valves
CN105555231B (en) 2013-08-01 2018-02-09 坦迪尼控股股份有限公司 External membrane of heart anchor and method
US10070857B2 (en) 2013-08-31 2018-09-11 Mitralign, Inc. Devices and methods for locating and implanting tissue anchors at mitral valve commissure
WO2015058039A1 (en) 2013-10-17 2015-04-23 Robert Vidlund Apparatus and methods for alignment and deployment of intracardiac devices
US10299793B2 (en) 2013-10-23 2019-05-28 Valtech Cardio, Ltd. Anchor magazine
US10166098B2 (en) 2013-10-25 2019-01-01 Middle Peak Medical, Inc. Systems and methods for transcatheter treatment of valve regurgitation
CA2924389C (en) 2013-10-28 2021-11-09 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US10052095B2 (en) 2013-10-30 2018-08-21 4Tech Inc. Multiple anchoring-point tension system
US10022114B2 (en) 2013-10-30 2018-07-17 4Tech Inc. Percutaneous tether locking
US9610162B2 (en) 2013-12-26 2017-04-04 Valtech Cardio, Ltd. Implantation of flexible implant
WO2015120122A2 (en) 2014-02-05 2015-08-13 Robert Vidlund Apparatus and methods for transfemoral delivery of prosthetic mitral valve
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
CA2937566C (en) 2014-03-10 2023-09-05 Tendyne Holdings, Inc. Devices and methods for positioning and monitoring tether load for prosthetic mitral valve
EP3134033B1 (en) 2014-05-29 2018-04-04 Edwards Lifesciences CardiAQ LLC Prosthesis and delivery device
CA2958061A1 (en) 2014-06-18 2015-12-23 Middle Peak Medical, Inc. Mitral valve implants for the treatment of valvular regurgitation
US9801720B2 (en) 2014-06-19 2017-10-31 4Tech Inc. Cardiac tissue cinching
JP6740140B2 (en) 2014-06-24 2020-08-12 ポラレス・メディカル・インコーポレイテッド System and method for securing an implant
WO2016059639A1 (en) 2014-10-14 2016-04-21 Valtech Cardio Ltd. Leaflet-restraining techniques
JP6717820B2 (en) 2014-12-02 2020-07-08 4テック インコーポレイテッド Eccentric tissue anchor
JP6826035B2 (en) 2015-01-07 2021-02-03 テンダイン ホールディングス,インコーポレイテッド Artificial mitral valve, and devices and methods for its delivery
JP6718459B2 (en) 2015-02-05 2020-07-08 テンダイン ホールディングス,インコーポレイテッド Expandable epicardial pad and device and methods of delivery thereof
WO2016125160A1 (en) 2015-02-05 2016-08-11 Mitraltech Ltd. Prosthetic valve with axially-sliding frames
US20160256269A1 (en) 2015-03-05 2016-09-08 Mitralign, Inc. Devices for treating paravalvular leakage and methods use thereof
WO2016168609A1 (en) 2015-04-16 2016-10-20 Tendyne Holdings, Inc. Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves
CN111265335B (en) 2015-04-30 2022-03-15 瓦尔泰克卡迪欧有限公司 Valvuloplasty techniques
US10314707B2 (en) 2015-06-09 2019-06-11 Edwards Lifesciences, Llc Asymmetric mitral annuloplasty band
CR20170577A (en) 2015-07-02 2019-05-03 Edwards Lifesciences Corp Hybrid heart valves adapted for post-implant expansion.-
EP3316823B1 (en) 2015-07-02 2020-04-08 Edwards Lifesciences Corporation Integrated hybrid heart valves
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US9592121B1 (en) 2015-11-06 2017-03-14 Middle Peak Medical, Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
AU2016362474B2 (en) 2015-12-03 2021-04-22 Tendyne Holdings, Inc. Frame features for prosthetic mitral valves
JP6795591B2 (en) 2015-12-28 2020-12-02 テンダイン ホールディングス,インコーポレイテッド Atrial pocket closure for artificial heart valve
US10828160B2 (en) 2015-12-30 2020-11-10 Edwards Lifesciences Corporation System and method for reducing tricuspid regurgitation
US10751182B2 (en) 2015-12-30 2020-08-25 Edwards Lifesciences Corporation System and method for reshaping right heart
CN108882981B (en) 2016-01-29 2021-08-10 内奥瓦斯克迪亚拉公司 Prosthetic valve for preventing outflow obstruction
US10470877B2 (en) 2016-05-03 2019-11-12 Tendyne Holdings, Inc. Apparatus and methods for anterior valve leaflet management
US20200146854A1 (en) 2016-05-16 2020-05-14 Elixir Medical Corporation Methods and devices for heart valve repair
US10702274B2 (en) 2016-05-26 2020-07-07 Edwards Lifesciences Corporation Method and system for closing left atrial appendage
WO2017218375A1 (en) 2016-06-13 2017-12-21 Tendyne Holdings, Inc. Sequential delivery of two-part prosthetic mitral valve
EP3478224B1 (en) 2016-06-30 2022-11-02 Tendyne Holdings, Inc. Prosthetic heart valves and apparatus for delivery of same
GB201611910D0 (en) 2016-07-08 2016-08-24 Valtech Cardio Ltd Adjustable annuloplasty device with alternating peaks and troughs
EP3484411A1 (en) 2016-07-12 2019-05-22 Tendyne Holdings, Inc. Apparatus and methods for trans-septal retrieval of prosthetic heart valves
EP3848003A1 (en) 2016-08-10 2021-07-14 Cardiovalve Ltd. Prosthetic valve with concentric frames
US10722356B2 (en) 2016-11-03 2020-07-28 Edwards Lifesciences Corporation Prosthetic mitral valve holders
WO2018090148A1 (en) 2016-11-21 2018-05-24 Neovasc Tiara Inc. Methods and systems for rapid retraction of a transcatheter heart valve delivery system
WO2018119304A1 (en) 2016-12-22 2018-06-28 Heart Repair Technologies, Inc. Percutaneous delivery systems for anchoring an implant in a cardiac valve annulus
US10478303B2 (en) 2017-03-13 2019-11-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
JP7159230B2 (en) 2017-03-13 2022-10-24 ポラレス・メディカル・インコーポレイテッド Devices, systems and methods for transcatheter treatment of valvular regurgitation
US10653524B2 (en) 2017-03-13 2020-05-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
US11045627B2 (en) 2017-04-18 2021-06-29 Edwards Lifesciences Corporation Catheter system with linear actuation control mechanism
WO2019014473A1 (en) 2017-07-13 2019-01-17 Tendyne Holdings, Inc. Prosthetic heart valves and apparatus and methods for delivery of same
WO2019036810A1 (en) 2017-08-25 2019-02-28 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
WO2019046099A1 (en) 2017-08-28 2019-03-07 Tendyne Holdings, Inc. Prosthetic heart valves with tether coupling features
US10835221B2 (en) 2017-11-02 2020-11-17 Valtech Cardio, Ltd. Implant-cinching devices and systems
US11135062B2 (en) 2017-11-20 2021-10-05 Valtech Cardio Ltd. Cinching of dilated heart muscle
CN111655200B (en) 2018-01-24 2023-07-14 爱德华兹生命科学创新(以色列)有限公司 Contraction of annuloplasty structures
EP4248904A3 (en) 2018-01-26 2023-11-29 Edwards Lifesciences Innovation (Israel) Ltd. Techniques for facilitating heart valve tethering and chord replacement
USD944398S1 (en) 2018-06-13 2022-02-22 Edwards Lifesciences Corporation Expanded heart valve stent
WO2020012481A2 (en) 2018-07-12 2020-01-16 Valtech Cardio, Ltd. Annuloplasty systems and locking tools therefor
CN112437651B (en) 2018-07-30 2024-01-16 爱德华兹生命科学公司 Minimally Invasive Low Strain Annuloplasty Ring
US11737872B2 (en) 2018-11-08 2023-08-29 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
CA3135753C (en) 2019-04-01 2023-10-24 Neovasc Tiara Inc. Controllably deployable prosthetic valve
CA3136334A1 (en) 2019-04-10 2020-10-15 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
WO2020236931A1 (en) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Introducer with hemostasis mechanism
CN114144144A (en) 2019-06-20 2022-03-04 内奥瓦斯克迪亚拉公司 Low-profile prosthetic mitral valve
EP4193934A1 (en) 2019-10-29 2023-06-14 Edwards Lifesciences Innovation (Israel) Ltd. Annuloplasty and tissue anchor technologies
US11648110B2 (en) 2019-12-05 2023-05-16 Tendyne Holdings, Inc. Braided anchor for mitral valve
EP4076284A1 (en) 2019-12-16 2022-10-26 Edwards Lifesciences Corporation Valve holder assembly with suture looping protection
US11648114B2 (en) 2019-12-20 2023-05-16 Tendyne Holdings, Inc. Distally loaded sheath and loading funnel
US11678980B2 (en) 2020-08-19 2023-06-20 Tendyne Holdings, Inc. Fully-transseptal apical pad with pulley for tensioning
US11464634B2 (en) 2020-12-16 2022-10-11 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation with secondary anchors
US11759321B2 (en) 2021-06-25 2023-09-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation

Citations (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3656185A (en) * 1969-02-04 1972-04-18 Rhone Poulenc Sa Cardiac valvular support prosthesis
US4275469A (en) * 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4602911A (en) * 1982-08-19 1986-07-29 General Resorts S.A. Adjustable ringprosthesis
US4914097A (en) * 1987-02-25 1990-04-03 Mitsubishi Kasei Corporation N-indanyl carboxamide derivative and agricultural/horticultural fungicide containing the derivative as active ingredient
US4993428A (en) * 1990-02-12 1991-02-19 Microstrain Company Method of and means for implanting a pressure and force sensing apparatus
US5010892A (en) * 1988-05-04 1991-04-30 Triangle Research And Development Corp. Body lumen measuring instrument
US5104407A (en) * 1989-02-13 1992-04-14 Baxter International Inc. Selectively flexible annuloplasty ring
US5201880A (en) * 1992-01-27 1993-04-13 Pioneering Technologies, Inc. Mitral and tricuspid annuloplasty rings
US5306296A (en) * 1992-08-21 1994-04-26 Medtronic, Inc. Annuloplasty and suture rings
US5316016A (en) * 1992-07-07 1994-05-31 Scimed Life Systems, Inc. Imaging balloon catheter and methods for use and manufacture
US5396887A (en) * 1993-09-23 1995-03-14 Cardiac Pathways Corporation Apparatus and method for detecting contact pressure
US5480424A (en) * 1993-11-01 1996-01-02 Cox; James L. Heart valve replacement using flexible tubes
US5496336A (en) * 1989-07-31 1996-03-05 Baxter International Inc. Flexible suture guide and holder
US5533515A (en) * 1994-08-11 1996-07-09 Foster-Miller Solid state sphincter myometers
US5593435A (en) * 1994-07-29 1997-01-14 Baxter International Inc. Distensible annuloplasty ring for surgical remodelling of an atrioventricular valve and nonsurgical method for post-implantation distension thereof to accommodate patient growth
US5607471A (en) * 1993-08-03 1997-03-04 Jacques Seguin Prosthetic ring for heart surgery
US5728064A (en) * 1994-09-16 1998-03-17 Scimed Life Systems, Inc. Balloon catheter with improved pressure source
US5733331A (en) * 1992-07-28 1998-03-31 Newcor Industrial S.A. Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heat replacement
US5752522A (en) * 1995-05-04 1998-05-19 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US5776189A (en) * 1997-03-05 1998-07-07 Khalid; Naqeeb Cardiac valvular support prosthesis
US5855563A (en) * 1992-11-02 1999-01-05 Localmed, Inc. Method and apparatus for sequentially performing multiple intraluminal procedures
US5865801A (en) * 1995-07-18 1999-02-02 Houser; Russell A. Multiple compartmented balloon catheter with external pressure sensing
US5919147A (en) * 1996-11-01 1999-07-06 Jain; Krishna M. Method and apparatus for measuring the vascular diameter of a vessel
US5921935A (en) * 1989-09-18 1999-07-13 The Research Foundation Of State University Of New York Method and apparatus utilizing heart sounds for determining pressures associated with the left atrium
US5924984A (en) * 1997-01-30 1999-07-20 University Of Iowa Research Foundation Anorectal probe apparatus having at least one muscular activity sensor
US6010531A (en) * 1993-02-22 2000-01-04 Heartport, Inc. Less-invasive devices and methods for cardiac valve surgery
US6019739A (en) * 1998-06-18 2000-02-01 Baxter International Inc. Minimally invasive valve annulus sizer
US6024918A (en) * 1998-03-13 2000-02-15 Medtronic, Inc. Method for attachment of biomolecules to surfaces of medical devices
US6066160A (en) * 1998-11-23 2000-05-23 Quickie Llc Passive knotless suture terminator for use in minimally invasive surgery and to facilitate standard tissue securing
US6081737A (en) * 1997-03-28 2000-06-27 Shah; Ajit Apparatus for vascular mapping and methods of use
US6083179A (en) * 1996-05-20 2000-07-04 Formo Medical Ab (Publ.) Sensor to detect changes in the cross section of an elongated body cavity
US6183512B1 (en) * 1999-04-16 2001-02-06 Edwards Lifesciences Corporation Flexible annuloplasty system
US6187040B1 (en) * 1999-05-03 2001-02-13 John T. M. Wright Mitral and tricuspid annuloplasty rings
US6217610B1 (en) * 1994-07-29 2001-04-17 Edwards Lifesciences Corporation Expandable annuloplasty ring
US6231602B1 (en) * 1999-04-16 2001-05-15 Edwards Lifesciences Corporation Aortic annuloplasty ring
US6250308B1 (en) * 1998-06-16 2001-06-26 Cardiac Concepts, Inc. Mitral valve annuloplasty ring and method of implanting
US6258122B1 (en) * 1995-11-01 2001-07-10 St. Jude Medical, Inc. Bioresorbable annuloplasty prosthesis
US6406493B1 (en) * 2000-06-02 2002-06-18 Hosheng Tu Expandable annuloplasty ring and methods of use
US6406420B1 (en) * 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6409759B1 (en) * 1999-12-30 2002-06-25 St. Jude Medical, Inc. Harvested tissue heart valve with sewing rim
US6419696B1 (en) * 2000-07-06 2002-07-16 Paul A. Spence Annuloplasty devices and related heart valve repair methods
US20030033009A1 (en) * 2000-05-22 2003-02-13 Shlomo Gabbay Cardiac prosthesis for helping improve operation of a heat valve
US20030040793A1 (en) * 2001-08-24 2003-02-27 Salvador Marquez Self-molding annuloplasty ring and method of use
US20030078653A1 (en) * 2001-06-15 2003-04-24 Ivan Vesely Tissue engineered mitral valve chordae and methods of making and using same
US20030083742A1 (en) * 2000-02-02 2003-05-01 Paul A. Spence Heart valve repair apparatus and methods
US20030093148A1 (en) * 2001-11-13 2003-05-15 Bolling Steven F. Mitral valve annuloplasty ring for molding left ventricle geometry
US20030105519A1 (en) * 1997-09-04 2003-06-05 Roland Fasol Artificial chordae replacement
US20040006384A1 (en) * 2002-07-08 2004-01-08 Mccarthy Patrick Mitral valve annuluplasty ring having a posterior bow
US6709456B2 (en) * 2000-01-31 2004-03-23 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty with hemodynamic monitoring
US6719786B2 (en) * 2002-03-18 2004-04-13 Medtronic, Inc. Flexible annuloplasty prosthesis and holder
US6718985B2 (en) * 2001-04-24 2004-04-13 Edwin J. Hlavka Method and apparatus for catheter-based annuloplasty using local plications
US6723038B1 (en) * 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6726717B2 (en) * 2001-05-17 2004-04-27 Edwards Lifesciences Corporation Annular prosthesis for mitral valve
US6726715B2 (en) * 2001-10-23 2004-04-27 Childrens Medical Center Corporation Fiber-reinforced heart valve prosthesis
US6749639B2 (en) * 2001-08-27 2004-06-15 Mayo Foundation For Medical Education And Research Coated prosthetic implant
US20040122513A1 (en) * 2002-10-10 2004-06-24 Navia Jose?Apos; Luis Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve having chordae
US6764510B2 (en) * 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US20050043791A1 (en) * 2001-08-28 2005-02-24 Mccarthy Patrick M. Three-dimensional annuloplasty ring and template
US20050070999A1 (en) * 2000-02-02 2005-03-31 Spence Paul A. Heart valve repair apparatus and methods
US20050075727A1 (en) * 2001-10-29 2005-04-07 Wheatley David John Mitral valve prosthesis
US20050131533A1 (en) * 2001-05-17 2005-06-16 Ottavio Alfieri Annuloplasty rings for repair of abnormal mitral valves
US6908482B2 (en) * 2001-08-28 2005-06-21 Edwards Lifesciences Corporation Three-dimensional annuloplasty ring and template
US6918917B1 (en) * 2000-10-10 2005-07-19 Medtronic, Inc. Minimally invasive annuloplasty procedure and apparatus
US6986775B2 (en) * 2002-06-13 2006-01-17 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US20060015179A1 (en) * 2004-07-19 2006-01-19 Neil Bulman-Fleming Aortic annuloplasty ring
US20060015178A1 (en) * 2004-07-15 2006-01-19 Shahram Moaddeb Implants and methods for reshaping heart valves
US20060020336A1 (en) * 2001-10-23 2006-01-26 Liddicoat John R Automated annular plication for mitral valve repair
US20060025856A1 (en) * 2001-03-15 2006-02-02 Medtronic, Inc. Annuloplasty band and method
US20060025858A1 (en) * 2004-07-27 2006-02-02 Alameddine Abdallah K Mitral valve ring for treatment of mitral valve regurgitation
US20060030885A1 (en) * 2002-10-15 2006-02-09 Hyde Gregory M Apparatuses and methods for heart valve repair
US7037334B1 (en) * 2001-04-24 2006-05-02 Mitralign, Inc. Method and apparatus for catheter-based annuloplasty using local plications
US7166127B2 (en) * 2003-12-23 2007-01-23 Mitralign, Inc. Tissue fastening systems and methods utilizing magnetic guidance
US20070038294A1 (en) * 2004-01-21 2007-02-15 Navia Jose L Method and apparatus for replacing a mitral valve and an aortic valve with a homograft
US20070049952A1 (en) * 2005-08-30 2007-03-01 Weiss Steven J Apparatus and method for mitral valve repair without cardiopulmonary bypass, including transmural techniques
US20070066863A1 (en) * 2005-08-31 2007-03-22 Medtronic Vascular, Inc. Device for treating mitral valve regurgitation
US20070100439A1 (en) * 2005-10-31 2007-05-03 Medtronic Vascular, Inc. Chordae tendinae restraining ring
US20070118151A1 (en) * 2005-11-21 2007-05-24 The Brigham And Women's Hospital, Inc. Percutaneous cardiac valve repair with adjustable artificial chordae
US20070123979A1 (en) * 2005-06-27 2007-05-31 Patrick Perier Apparatus, system, and method for treatment of posterior leaflet prolapse
US20070162111A1 (en) * 2005-07-06 2007-07-12 The Cleveland Clinic Foundation Apparatus and method for replacing a cardiac valve
US7247134B2 (en) * 2002-11-12 2007-07-24 Myocor, Inc. Devices and methods for heart valve treatment
US20070173930A1 (en) * 2006-01-20 2007-07-26 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US20090192604A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Sizer, Holder and Delivery Devices for Minimally Invasive Cardiac Surgery
US20090192605A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Sizer Device Having a Plurality of Anterior-Posterior Ratios

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2306671A1 (en) * 1975-04-11 1976-11-05 Rhone Poulenc Ind VALVULAR IMPLANT
FR2298313A1 (en) 1975-06-23 1976-08-20 Usifroid LINEAR REDUCER FOR VALVULOPLASTY
US4164046A (en) 1977-05-16 1979-08-14 Cooley Denton Valve prosthesis
CA1303298C (en) 1986-08-06 1992-06-16 Alain Carpentier Flexible cardiac valvular support prosthesis
US4790844A (en) 1987-01-30 1988-12-13 Yoel Ovil Replacement of cardiac valves in heart surgery
IT1218951B (en) 1988-01-12 1990-04-24 Mario Morea PROSTHETIC DEVICE FOR SURGICAL CORRECTION OF TRICUSPIDAL INSUFFICENCE
US5041130A (en) 1989-07-31 1991-08-20 Baxter International Inc. Flexible annuloplasty ring and holder
US5064431A (en) 1991-01-16 1991-11-12 St. Jude Medical Incorporated Annuloplasty ring
DK0583410T3 (en) 1991-05-16 2001-11-12 Mures Cardiovascular Res Inc Heart valve
US5704361A (en) 1991-11-08 1998-01-06 Mayo Foundation For Medical Education And Research Volumetric image ultrasound transducer underfluid catheter system
DE69331315T2 (en) 1992-01-27 2002-08-22 Medtronic Inc ANULOPLASTIC AND SEAM RINGS
US5258021A (en) 1992-01-27 1993-11-02 Duran Carlos G Sigmoid valve annuloplasty ring
US5972030A (en) 1993-02-22 1999-10-26 Heartport, Inc. Less-invasive devices and methods for treatment of cardiac valves
US5450860A (en) 1993-08-31 1995-09-19 W. L. Gore & Associates, Inc. Device for tissue repair and method for employing same
US5573007A (en) 1994-08-08 1996-11-12 Innerspace, Inc. Gas column pressure monitoring catheters
US5814098A (en) 1995-06-07 1998-09-29 St. Jude Medical, Inc. Adjustable sizing apparatus
GB9519194D0 (en) 1995-09-20 1995-11-22 Univ Wales Medicine Anorectal angle measurement
AU720907B2 (en) 1995-12-01 2000-06-15 Medtronic, Inc. Annuloplasty prosthesis
US5662704A (en) 1995-12-01 1997-09-02 Medtronic, Inc. Physiologic mitral valve bioprosthesis
WO1997037618A1 (en) 1996-04-08 1997-10-16 Medtronic, Inc. Method of fixing a physiologic mitral valve bioprosthesis
EP0930857B1 (en) 1996-09-13 2003-05-02 Medtronic, Inc. Prosthetic heart valve with suturing member having non-uniform radial width
US5848969A (en) 1996-10-28 1998-12-15 Ep Technologies, Inc. Systems and methods for visualizing interior tissue regions using expandable imaging structures
EP0860151A1 (en) 1997-02-25 1998-08-26 Naqeeb Khalid Cardiac valvular support prosthesis
US5921934A (en) 1997-11-25 1999-07-13 Scimed Life Systems, Inc. Methods and apparatus for non-uniform rotation distortion detection in an intravascular ultrasound imaging system
US6332893B1 (en) 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
US6143024A (en) 1998-06-04 2000-11-07 Sulzer Carbomedics Inc. Annuloplasty ring having flexible anterior portion
US6159240A (en) 1998-08-31 2000-12-12 Medtronic, Inc. Rigid annuloplasty device that becomes compliant after implantation
US6102945A (en) * 1998-10-16 2000-08-15 Sulzer Carbomedics, Inc. Separable annuloplasty ring
DE19910233A1 (en) 1999-03-09 2000-09-21 Jostra Medizintechnik Ag Anuloplasty prosthesis
US6312464B1 (en) 1999-04-28 2001-11-06 NAVIA JOSé L. Method of implanting a stentless cardiac valve prosthesis
US6602289B1 (en) 1999-06-08 2003-08-05 S&A Rings, Llc Annuloplasty rings of particular use in surgery for the mitral valve
US6977950B1 (en) 1999-11-29 2005-12-20 Lucent Technologies Inc. Power distribution network for optoelectronic circuits
US6942694B2 (en) 2000-01-14 2005-09-13 Viacor, Inc. Tissue annuloplasty band and apparatus and method for fashioning, sizing and implanting the same
US6805711B2 (en) 2000-06-02 2004-10-19 3F Therapeutics, Inc. Expandable medical implant and percutaneous delivery
US6602288B1 (en) 2000-10-05 2003-08-05 Edwards Lifesciences Corporation Minimally-invasive annuloplasty repair segment delivery template, system and method of use
US6786924B2 (en) 2001-03-15 2004-09-07 Medtronic, Inc. Annuloplasty band and method
US6800090B2 (en) 2001-05-14 2004-10-05 Cardiac Dimensions, Inc. Mitral valve therapy device, system and method
ATE387160T1 (en) 2001-08-31 2008-03-15 Mitral Interventions DEVICE FOR HEART VALVE REPAIR
US6949122B2 (en) 2001-11-01 2005-09-27 Cardiac Dimensions, Inc. Focused compression mitral valve device and method
US6830586B2 (en) 2002-02-28 2004-12-14 3F Therapeutics, Inc. Stentless atrioventricular heart valve fabricated from a singular flat membrane
US7118595B2 (en) 2002-03-18 2006-10-10 Medtronic, Inc. Flexible annuloplasty prosthesis and holder
AU2003247526A1 (en) 2002-06-12 2003-12-31 Mitral Interventions, Inc. Method and apparatus for tissue connection
US7608103B2 (en) 2002-07-08 2009-10-27 Edwards Lifesciences Corporation Mitral valve annuloplasty ring having a posterior bow
US6966924B2 (en) 2002-08-16 2005-11-22 St. Jude Medical, Inc. Annuloplasty ring holder
KR101050626B1 (en) 2002-08-29 2011-07-19 미트랄 솔루션스, 인크. Implantation device for controlling the inner circumference of the anatomical orifice or lumen
US7112219B2 (en) 2002-11-12 2006-09-26 Myocor, Inc. Devices and methods for heart valve treatment
EP1608297A2 (en) 2003-03-18 2005-12-28 St. Jude Medical, Inc. Body tissue remodeling apparatus
US6945996B2 (en) 2003-04-18 2005-09-20 Sedransk Kyra L Replacement mitral valve
WO2005004753A1 (en) 2003-06-09 2005-01-20 3F Therapeutics, Inc. Atrioventricular heart valve and minimally invasive delivery systems thereof
WO2004112651A2 (en) 2003-06-20 2004-12-29 Medtronic Vascular, Inc. Chordae tendinae girdle
CA2539459C (en) 2003-10-03 2012-04-24 Edwards Lifesciences Corporation Annuloplasty rings for repair of abnormal mitral valves
US8206439B2 (en) 2004-02-23 2012-06-26 International Heart Institute Of Montana Foundation Internal prosthesis for reconstruction of cardiac geometry
US7294148B2 (en) 2004-04-29 2007-11-13 Edwards Lifesciences Corporation Annuloplasty ring for mitral valve prolapse
US20050256568A1 (en) 2004-05-14 2005-11-17 St. Jude Medical, Inc. C-shaped heart valve prostheses
US7452376B2 (en) 2004-05-14 2008-11-18 St. Jude Medical, Inc. Flexible, non-planar annuloplasty rings
US7938856B2 (en) 2004-05-14 2011-05-10 St. Jude Medical, Inc. Heart valve annuloplasty prosthesis sewing cuffs and methods of making same
EP2433591B1 (en) 2004-05-14 2016-04-27 St. Jude Medical, Inc. Apparatus for holding an annuloplasty ring
US20050278022A1 (en) 2004-06-14 2005-12-15 St. Jude Medical, Inc. Annuloplasty prostheses with improved anchoring structures, and related methods
US20050288778A1 (en) 2004-06-29 2005-12-29 Emanuel Shaoulian Selectively adjustable cardiac valve implants
US20090043381A1 (en) 2004-10-05 2009-02-12 Macoviak John A Atrioventricular valve annulus repair systems and methods including retro-chordal anchors
ES2558534T3 (en) 2005-02-18 2016-02-05 The Cleveland Clinic Foundation Device to replace a heart valve
WO2006113906A1 (en) 2005-04-20 2006-10-26 The Cleveland Clinic Foundation Apparatus and method for replacing a cardiac valve
EP1903988A2 (en) 2005-06-07 2008-04-02 The International Heart Institute Of Montana Found A system, including method and apparatus for percutaneous endovascular treatment of functional mitral valve insufficiency
US20070100441A1 (en) 2005-10-26 2007-05-03 St. Jude Medical, Inc. Saddle-shaped mitral valve annuloplasty prostheses with asymmetry, and related methods
US9125742B2 (en) 2005-12-15 2015-09-08 Georgia Tech Research Foundation Papillary muscle position control devices, systems, and methods
US7431692B2 (en) 2006-03-09 2008-10-07 Edwards Lifesciences Corporation Apparatus, system, and method for applying and adjusting a tensioning element to a hollow body organ
CA2677968C (en) 2006-05-15 2014-07-08 Enovacor Aps A system and a method for altering the geometry of the heart
SE530568C2 (en) 2006-11-13 2008-07-08 Medtentia Ab Medical device for improving function of heart valve, has flange unit connected to loop-shaped support and provided to be arranged against annulus when loop shaped support abut heart valve
EP2091466A2 (en) 2006-11-17 2009-08-26 St.Jude Medical, Inc Prosthetic heart valve structures and related methods
EP3488822B1 (en) 2007-01-26 2020-10-21 Medtronic, Inc. Annuloplasty device for tricuspid valve repair
WO2008098226A1 (en) 2007-02-09 2008-08-14 Edwards Lifesciences Corporation Progressively sized annuloplasty rings

Patent Citations (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3656185A (en) * 1969-02-04 1972-04-18 Rhone Poulenc Sa Cardiac valvular support prosthesis
US4275469A (en) * 1979-12-13 1981-06-30 Shelhigh Inc. Prosthetic heart valve
US4602911A (en) * 1982-08-19 1986-07-29 General Resorts S.A. Adjustable ringprosthesis
US4914097A (en) * 1987-02-25 1990-04-03 Mitsubishi Kasei Corporation N-indanyl carboxamide derivative and agricultural/horticultural fungicide containing the derivative as active ingredient
US5010892A (en) * 1988-05-04 1991-04-30 Triangle Research And Development Corp. Body lumen measuring instrument
US5104407A (en) * 1989-02-13 1992-04-14 Baxter International Inc. Selectively flexible annuloplasty ring
US5104407B1 (en) * 1989-02-13 1999-09-21 Baxter Int Selectively flexible annuloplasty ring
US5496336A (en) * 1989-07-31 1996-03-05 Baxter International Inc. Flexible suture guide and holder
US5921935A (en) * 1989-09-18 1999-07-13 The Research Foundation Of State University Of New York Method and apparatus utilizing heart sounds for determining pressures associated with the left atrium
US4993428A (en) * 1990-02-12 1991-02-19 Microstrain Company Method of and means for implanting a pressure and force sensing apparatus
US5201880A (en) * 1992-01-27 1993-04-13 Pioneering Technologies, Inc. Mitral and tricuspid annuloplasty rings
US5316016A (en) * 1992-07-07 1994-05-31 Scimed Life Systems, Inc. Imaging balloon catheter and methods for use and manufacture
US5733331A (en) * 1992-07-28 1998-03-31 Newcor Industrial S.A. Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heat replacement
US5306296A (en) * 1992-08-21 1994-04-26 Medtronic, Inc. Annuloplasty and suture rings
US5855563A (en) * 1992-11-02 1999-01-05 Localmed, Inc. Method and apparatus for sequentially performing multiple intraluminal procedures
US6010531A (en) * 1993-02-22 2000-01-04 Heartport, Inc. Less-invasive devices and methods for cardiac valve surgery
US5607471A (en) * 1993-08-03 1997-03-04 Jacques Seguin Prosthetic ring for heart surgery
US5396887A (en) * 1993-09-23 1995-03-14 Cardiac Pathways Corporation Apparatus and method for detecting contact pressure
US5480424A (en) * 1993-11-01 1996-01-02 Cox; James L. Heart valve replacement using flexible tubes
US5593435A (en) * 1994-07-29 1997-01-14 Baxter International Inc. Distensible annuloplasty ring for surgical remodelling of an atrioventricular valve and nonsurgical method for post-implantation distension thereof to accommodate patient growth
US6217610B1 (en) * 1994-07-29 2001-04-17 Edwards Lifesciences Corporation Expandable annuloplasty ring
US6391054B2 (en) * 1994-07-29 2002-05-21 Edwards Lifesciences Corporation Expandable annuloplasty ring
US5888240A (en) * 1994-07-29 1999-03-30 Baxter International Inc. Distensible annuloplasty ring for surgical remodelling of an atrioventricular valve and nonsurgical method for post-implantation distension thereof to accomodate patient growth
US5533515A (en) * 1994-08-11 1996-07-09 Foster-Miller Solid state sphincter myometers
US5728064A (en) * 1994-09-16 1998-03-17 Scimed Life Systems, Inc. Balloon catheter with improved pressure source
US5902308A (en) * 1995-05-04 1999-05-11 Medtronic, Inc. Lesion diameter measurement catheter and method
US5752522A (en) * 1995-05-04 1998-05-19 Cardiovascular Concepts, Inc. Lesion diameter measurement catheter and method
US5865801A (en) * 1995-07-18 1999-02-02 Houser; Russell A. Multiple compartmented balloon catheter with external pressure sensing
US6258122B1 (en) * 1995-11-01 2001-07-10 St. Jude Medical, Inc. Bioresorbable annuloplasty prosthesis
US6083179A (en) * 1996-05-20 2000-07-04 Formo Medical Ab (Publ.) Sensor to detect changes in the cross section of an elongated body cavity
US5919147A (en) * 1996-11-01 1999-07-06 Jain; Krishna M. Method and apparatus for measuring the vascular diameter of a vessel
US6406420B1 (en) * 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US5924984A (en) * 1997-01-30 1999-07-20 University Of Iowa Research Foundation Anorectal probe apparatus having at least one muscular activity sensor
US5776189A (en) * 1997-03-05 1998-07-07 Khalid; Naqeeb Cardiac valvular support prosthesis
US6081737A (en) * 1997-03-28 2000-06-27 Shah; Ajit Apparatus for vascular mapping and methods of use
US20030105519A1 (en) * 1997-09-04 2003-06-05 Roland Fasol Artificial chordae replacement
US6024918A (en) * 1998-03-13 2000-02-15 Medtronic, Inc. Method for attachment of biomolecules to surfaces of medical devices
US6250308B1 (en) * 1998-06-16 2001-06-26 Cardiac Concepts, Inc. Mitral valve annuloplasty ring and method of implanting
US6019739A (en) * 1998-06-18 2000-02-01 Baxter International Inc. Minimally invasive valve annulus sizer
US6066160A (en) * 1998-11-23 2000-05-23 Quickie Llc Passive knotless suture terminator for use in minimally invasive surgery and to facilitate standard tissue securing
US6183512B1 (en) * 1999-04-16 2001-02-06 Edwards Lifesciences Corporation Flexible annuloplasty system
US6231602B1 (en) * 1999-04-16 2001-05-15 Edwards Lifesciences Corporation Aortic annuloplasty ring
US6187040B1 (en) * 1999-05-03 2001-02-13 John T. M. Wright Mitral and tricuspid annuloplasty rings
US6409759B1 (en) * 1999-12-30 2002-06-25 St. Jude Medical, Inc. Harvested tissue heart valve with sewing rim
US6709456B2 (en) * 2000-01-31 2004-03-23 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty with hemodynamic monitoring
US20060149368A1 (en) * 2000-02-02 2006-07-06 Spence Paul A Heart valve repair apparatus and methods
US20050070999A1 (en) * 2000-02-02 2005-03-31 Spence Paul A. Heart valve repair apparatus and methods
US7166126B2 (en) * 2000-02-02 2007-01-23 Paul A. Spence Heart valve repair apparatus and methods
US20030083742A1 (en) * 2000-02-02 2003-05-01 Paul A. Spence Heart valve repair apparatus and methods
US20090177278A1 (en) * 2000-02-02 2009-07-09 Spence Paul A Heart valve repair apparatus and methods
US7527647B2 (en) * 2000-02-02 2009-05-05 Spence Paul A Heart valve repair apparatus and methods
US20070050020A1 (en) * 2000-02-02 2007-03-01 Spence Paul A Heart valve repair apparatus and methods
US20040088047A1 (en) * 2000-02-02 2004-05-06 Paul A. Spence Heart valve repair apparatus and methods
US20030033009A1 (en) * 2000-05-22 2003-02-13 Shlomo Gabbay Cardiac prosthesis for helping improve operation of a heat valve
US6406493B1 (en) * 2000-06-02 2002-06-18 Hosheng Tu Expandable annuloplasty ring and methods of use
US6419696B1 (en) * 2000-07-06 2002-07-16 Paul A. Spence Annuloplasty devices and related heart valve repair methods
US6723038B1 (en) * 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6921407B2 (en) * 2000-10-10 2005-07-26 Medtronic, Inc. Minimally invasive annuloplasty procedure and apparatus
US6918917B1 (en) * 2000-10-10 2005-07-19 Medtronic, Inc. Minimally invasive annuloplasty procedure and apparatus
US20060025856A1 (en) * 2001-03-15 2006-02-02 Medtronic, Inc. Annuloplasty band and method
US7037334B1 (en) * 2001-04-24 2006-05-02 Mitralign, Inc. Method and apparatus for catheter-based annuloplasty using local plications
US6718985B2 (en) * 2001-04-24 2004-04-13 Edwin J. Hlavka Method and apparatus for catheter-based annuloplasty using local plications
US20050004666A1 (en) * 2001-05-17 2005-01-06 Ottavio Alfieri Annular prosthesis for mitral valve
US6726717B2 (en) * 2001-05-17 2004-04-27 Edwards Lifesciences Corporation Annular prosthesis for mitral valve
US20050131533A1 (en) * 2001-05-17 2005-06-16 Ottavio Alfieri Annuloplasty rings for repair of abnormal mitral valves
US20030078653A1 (en) * 2001-06-15 2003-04-24 Ivan Vesely Tissue engineered mitral valve chordae and methods of making and using same
US20030040793A1 (en) * 2001-08-24 2003-02-27 Salvador Marquez Self-molding annuloplasty ring and method of use
US6749639B2 (en) * 2001-08-27 2004-06-15 Mayo Foundation For Medical Education And Research Coated prosthetic implant
US20050043791A1 (en) * 2001-08-28 2005-02-24 Mccarthy Patrick M. Three-dimensional annuloplasty ring and template
US6908482B2 (en) * 2001-08-28 2005-06-21 Edwards Lifesciences Corporation Three-dimensional annuloplasty ring and template
US20060020336A1 (en) * 2001-10-23 2006-01-26 Liddicoat John R Automated annular plication for mitral valve repair
US6726715B2 (en) * 2001-10-23 2004-04-27 Childrens Medical Center Corporation Fiber-reinforced heart valve prosthesis
US20050075727A1 (en) * 2001-10-29 2005-04-07 Wheatley David John Mitral valve prosthesis
US7329280B2 (en) * 2001-11-13 2008-02-12 Edwards Lifesciences Corp. Methods of implanting a mitral valve annuloplasty ring to correct mitral regurgitation
US20030093148A1 (en) * 2001-11-13 2003-05-15 Bolling Steven F. Mitral valve annuloplasty ring for molding left ventricle geometry
US6764510B2 (en) * 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7066954B2 (en) * 2002-03-18 2006-06-27 Medtronic, Inc. Annuloplasty system
US6719786B2 (en) * 2002-03-18 2004-04-13 Medtronic, Inc. Flexible annuloplasty prosthesis and holder
US6986775B2 (en) * 2002-06-13 2006-01-17 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US20040006384A1 (en) * 2002-07-08 2004-01-08 Mccarthy Patrick Mitral valve annuluplasty ring having a posterior bow
US6858039B2 (en) * 2002-07-08 2005-02-22 Edwards Lifesciences Corporation Mitral valve annuloplasty ring having a posterior bow
US20040122513A1 (en) * 2002-10-10 2004-06-24 Navia Jose?Apos; Luis Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve having chordae
US20060030885A1 (en) * 2002-10-15 2006-02-09 Hyde Gregory M Apparatuses and methods for heart valve repair
US7247134B2 (en) * 2002-11-12 2007-07-24 Myocor, Inc. Devices and methods for heart valve treatment
US7166127B2 (en) * 2003-12-23 2007-01-23 Mitralign, Inc. Tissue fastening systems and methods utilizing magnetic guidance
US20070038294A1 (en) * 2004-01-21 2007-02-15 Navia Jose L Method and apparatus for replacing a mitral valve and an aortic valve with a homograft
US20060015178A1 (en) * 2004-07-15 2006-01-19 Shahram Moaddeb Implants and methods for reshaping heart valves
US20060015179A1 (en) * 2004-07-19 2006-01-19 Neil Bulman-Fleming Aortic annuloplasty ring
US20060025858A1 (en) * 2004-07-27 2006-02-02 Alameddine Abdallah K Mitral valve ring for treatment of mitral valve regurgitation
US20070123979A1 (en) * 2005-06-27 2007-05-31 Patrick Perier Apparatus, system, and method for treatment of posterior leaflet prolapse
US20070162111A1 (en) * 2005-07-06 2007-07-12 The Cleveland Clinic Foundation Apparatus and method for replacing a cardiac valve
US20070049952A1 (en) * 2005-08-30 2007-03-01 Weiss Steven J Apparatus and method for mitral valve repair without cardiopulmonary bypass, including transmural techniques
US20070066863A1 (en) * 2005-08-31 2007-03-22 Medtronic Vascular, Inc. Device for treating mitral valve regurgitation
US20070100439A1 (en) * 2005-10-31 2007-05-03 Medtronic Vascular, Inc. Chordae tendinae restraining ring
US20070118151A1 (en) * 2005-11-21 2007-05-24 The Brigham And Women's Hospital, Inc. Percutaneous cardiac valve repair with adjustable artificial chordae
US20070173930A1 (en) * 2006-01-20 2007-07-26 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US20090192604A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Sizer, Holder and Delivery Devices for Minimally Invasive Cardiac Surgery
US20090192602A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Deformable Sizer and Holder Devices for Minimally Invasive Cardiac Surgery
US20090192605A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Sizer Device Having a Plurality of Anterior-Posterior Ratios
US20090192603A1 (en) * 2008-01-25 2009-07-30 Medtronic, Inc. Adjustable Sizer Devices for Minimally Invasive Cardiac Surgery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9814574B2 (en) 2010-09-30 2017-11-14 BioStable Science & Engineering, Inc. Non-axisymmetric aortic valve devices

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US8529621B2 (en) 2013-09-10
ATE419808T1 (en) 2009-01-15
US6726717B2 (en) 2004-04-27
US20120172983A1 (en) 2012-07-05
US20020173844A1 (en) 2002-11-21
ITMI20011012A0 (en) 2001-05-17
EP1258232A2 (en) 2002-11-20
DE60230697D1 (en) 2009-02-26
US7674286B2 (en) 2010-03-09
EP1258232A3 (en) 2003-11-12
US20050004666A1 (en) 2005-01-06
EP1258232B1 (en) 2009-01-07

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