US20100159117A1 - Super Elastic Guidewire With Shape Retention Tip - Google Patents
Super Elastic Guidewire With Shape Retention Tip Download PDFInfo
- Publication number
- US20100159117A1 US20100159117A1 US12/715,299 US71529910A US2010159117A1 US 20100159117 A1 US20100159117 A1 US 20100159117A1 US 71529910 A US71529910 A US 71529910A US 2010159117 A1 US2010159117 A1 US 2010159117A1
- Authority
- US
- United States
- Prior art keywords
- polymer
- polymer jacket
- distal tip
- tip portion
- jacket
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/16—Materials with shape-memory or superelastic properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
- A61M2025/09141—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque made of shape memory alloys which take a particular shape at a certain temperature
Definitions
- the present invention generally relates to intravascular guidewires. More specifically, the present invention relates to intravascular guidewires utilizing super elastic materials.
- Intravascular guidewires are commonly used to navigate through a patient's vascular system for the diagnosis and treatment of a wide variety of vascular disorders.
- Guidewires conventionally utilize a stainless steel or nitinol (super elastic) core wire.
- Stainless steel core wires are advantageous because they are shapeable, but are disadvantageous because they may become deformed in tortuous vascular anatomy.
- Nitinol core wires are advantageous because they do not become deformed in tortuous vasculature, but are disadvantageous because they are not shapeable.
- the present invention provides several design alternatives.
- the present invention provides a guidewire having a super elastic core wire surrounded by a shape memory polymer jacket.
- the super elastic core wire permits the guidewire to be navigated through tortuous vasculature without undergoing plastic deformation, and the shape memory polymer jacket permits the guidewire to be shapeable.
- FIG. 1 is a plan view of a guidewire according to the present invention, in combination with a balloon catheter;
- FIG. 2 is a foreshortened longitudinal cross-sectional view of a distal portion of a guidewire of the present invention, showing a polymer jacket surrounding a distal tip of a core wire;
- FIG. 3 is a foreshortened longitudinal cross-sectional view of a portion of a guidewire of the present invention, showing a polymer jacket surrounding a mid portion of a core wire;
- FIGS. 4 and 5 are side views of a distal tip portion of a guide wire showing a polymer jacket surrounding a distal portion of a spring tip and core wire, wherein the distal tip is deformed about a cylinder-shaped object.
- FIG. 1 illustrates a plan view of a guidewire 10 in combination with an intravascular device 100 .
- the intravascular device 100 comprises a balloon catheter, but those skilled in the art will recognize that guidewires may be used alone or in combination with a wide variety of intravascular devices for coronary, peripheral and cerebral use, including balloon catheters, guide catheters, diagnostic catheters, micro-catheters, etc.
- intravascular device 100 is shown to be a balloon catheter 100 having an elongate shaft 102 , a proximally disposed manifold 104 , and a distally disposed inflatable balloon 106 , all of which are conventional in the art.
- Guidewire 10 may extend through the entire length of the balloon catheter 100 , and includes a proximal end 12 and a distal tip portion 14 .
- the guidewire 10 may have a size (length and diameter) to navigate coronary, peripheral and/or cerebral vasculature, depending on the particular clinical application, and the distal tip portion 14 may be shaped to facilitate steering in such vascular anatomy.
- the guidewire 10 may include a core wire 20 with a polymer jacket 50 surrounding a distal tip portion 14 thereof.
- the polymer jacket 50 may surround a mid portion of the guidewire 10 as shown in FIG. 3 .
- a radiopaque coil 40 may surround a distal portion 14 of the core wire 20 , with a distal weld 42 connecting the distal end of the coil 40 to the distal end of the core wire 20 (not visible in FIGS. 4 and 5 ).
- the polymer jacket 50 may surround the core wire 20 and the radiopaque coil 40 .
- the polymer jacket 50 may surround an inner polymer jacket (not shown) disposed on the core wire 20 , resulting in a multi-layered polymer jacket arrangement, with layer thicknesses that may vary, but preferably do not exceed the proximal profile of the guidewire.
- the polymer jacket 50 may incorporate radiopaque filler.
- the polymer jacket 50 may surround the core wire 20 and/or radiopaque coil 40 to establish contact therebetween or to establish an annular space therebetween.
- the polymer jacket 50 may surround and encase the core wire 20 and/or radiopaque coil 40 to encase the distal tip 14 as shown in FIGS. 2 , 4 and 5 , or merely surround a portion thereof without encasing as shown in FIG. 3 .
- Core wire 20 may comprise a stainless steel metal or a super elastic metal such as nitinol (nickel titanium alloy) for purposes of navigating tortuous vasculature without causing plastic deformation thereof.
- Polymer jacket 50 may comprise a polymer and may have suitable dimensions and material characteristics that render the polymer jacket 50 more stiff than the distal tip portion 14 of the super elastic core wire 20 which it surrounds.
- stiff or stiffness refers to the collective property defined by material characteristics and shape, as conventionally used in mechanical engineering design.
- the cross-sectional bending moment and the flexural modulus of the polymer jacket 50 may be selected such that when the tip 14 is deformed into a shape within the elastic limit of the super elastic core wire 20 , and beyond the elastic limit of the polymer, the tip 14 substantially retains the shape, although some recoil may occur.
- the polymer jacket 50 may comprise a shape memory polymer such as shape memory polyurethane available from Mitsubishi, polynorbornene polymers and copolymers (including blends with polyethylene and KRATON), polycaprolactone or (oligo)caprolactone copolymer, polymethylmethacylate, PLLA or PL/D LA copolymer, PLLA PGA copolymer, PMMA, cross-linked polyethylene, cross-linked polyisoprene, polycyclooctene, styrene-butadiene copolymer, or photocrosslinkable polymer including azo-dye, zwitterionic and other photoschromic materials (as referenced in Shape memory Materials, Otsuka and Wayman, Cambridge University press, ⁇ 1998).
- shape memory polymer such as shape memory polyurethane available from Mitsubishi, polynorbornene polymers and copolymers (including blends with polyethylene and KRATON), polycaprolactone or (oligo)caprolactone cop
- the distal tip 14 may be deformed into the desired shape.
- the distal tip portion 14 may be deformed about a cylindrical object 90 to impart a J-tip shape as shown in FIG. 4 , or a bent-L shape as shown in FIG. 5 .
- the polymer jacket 50 may be subjected to heat at a temperature at or above the glass transition temperature (or near the melt temperature) of the shape memory polymer, and subsequently cooled to a temperature below the glass transition temperature.
- the glass transition temperature is preferably greater than the temperature of the environment where guidewire 10 will be used (i.e., the internal body temperature of a patient), so as to sustain the desired shape while guidewire 10 is used (e.g., navigated through a vessel lumen of a patient). In other words, the temperature of the environment where guidewire 10 will be used is lower than the glass transition temperature that will allow polymer jacket 50 to change shape.
- the elastic forces of the super elastic core wire 20 work against the polymer jacket 50 , biasing the shape of the distal tip back to the original (e.g., straight) configuration.
- the polymer jacket 50 has sufficient stiffness, by virtue of its size and its material properties, to substantially oppose, if not completely offset, the biasing force of the super elastic core wire 20 .
- the biasing force of the core wire 20 may be reduced by reducing the size (e.g., diameter) thereof, and the opposing force of the polymer jacket 50 may be increased by increasing the size (cross-sectional area moment) and/or the flexural modulus thereof
- the polymer jacket 50 substantially maintains the deformed shape, although some recoil may occur. To compensate for such recoil, the deformed shape may be exaggerated relative to the desired final shape.
- the distal tip 14 may be re-shaped by re-deforming the distal tip 14 and exposing the polymer jacket 50 to heat at a temperature at or above the glass transition temperature (or near the melt temperature) of the shape memory polymer, and subsequently cooled to a temperature below the glass transition temperature.
- the original (e.g., straight) configuration of the distal tip 14 may be recaptured by exposing the polymer jacket 50 to heat at a temperature at or above the transformation temperature of the shape memory polymer, followed by cooling.
- the distal tip 14 may be repeatedly shaped without compromising shapeability or guidewire performance.
- the polymer jacket 50 may surround the distal tip portion 14 as shown in FIG. 2 or a mid portion of the core wire 20 as shown in FIG. 3 .
- the core wire 20 may be ground to have a single taper or a series of tapers as shown in FIG. 2 or ground to define a recess as shown in FIG. 3 .
- the distal portion 14 of the core wire 20 includes a series of tapers to accommodate the polymer jacket 50 and to provide a gradual reduction in stiffness toward the distal end thereof.
- the core wire 20 may have a proximal uniform diameter portion 22 having a diameter of about 0.007 to 0.038 inches and a length “A” of about 100 to 260 cm, a mid uniform diameter portion 26 having a diameter of about 0.003 to 0.010 inches and a length “C” of about 5 to 30 cm, and a distal uniform diameter portion 30 having a diameter of about 0.0015 to 0.005 inches and a length “E” of about 5 to 30 cm.
- distal portion 30 may comprise a flat ribbon having a thickness of 0.0015 to 0.005 inches.
- the core wire 20 may also include tapered portions 24 / 28 between the uniform diameter portions 22 / 26 / 30 , having tapering diameters and lengths “B” and “D” of about 0.1 to 10 cm to provide a smooth transition between the uniform diameter portions 22 / 26 / 30 .
- the core wire 20 may have a continuous taper terminating in a radiopaque tip, and covered by the polymer jacket 50 .
- a mid portion (i.e., a portion that is proximal of the distal end and distal of the proximal end) of the core wire 20 is provided with an optional recess having a uniform diameter portion 34 and two tapered portions 32 / 36 .
- the position of the recess 34 and thus the position of the polymer jacket 50 in this embodiment is dictated by the length “F” of the proximal uniform diameter portion 22 and the length “J” of the distal uniform diameter portion 38 .
- the length “H” of the recess portion 34 may be selected depending on the desired shapeable length of the core wire 20 .
- the lengths “G” and “I” of the tapered portion 32 / 36 may be the same or similar to that of tapered portions 24 / 28 described previously.
Abstract
A guidewire having a super elastic core surrounded by a shape memory polymer jacket. The super elastic core wire permits the guidewire to be navigated through tortuous vasculature without undergoing plastic deformation, and the shape memory polymer jacket permits the guidewire to be shaped by the physician.
Description
- This application is a continuation of U.S. application Ser. No. 10/025,668, filed Dec. 18, 2001, the entire disclosure of which is incorporated herein by reference.
- The present invention generally relates to intravascular guidewires. More specifically, the present invention relates to intravascular guidewires utilizing super elastic materials.
- Intravascular guidewires are commonly used to navigate through a patient's vascular system for the diagnosis and treatment of a wide variety of vascular disorders. Guidewires conventionally utilize a stainless steel or nitinol (super elastic) core wire. Stainless steel core wires are advantageous because they are shapeable, but are disadvantageous because they may become deformed in tortuous vascular anatomy. Nitinol core wires are advantageous because they do not become deformed in tortuous vasculature, but are disadvantageous because they are not shapeable. Thus, there is a need for a guidewire that offers both advantages, namely a guidewire that is shapeable and that is not readily deformed in tortuous vasculature.
- To address this need, the present invention provides several design alternatives. For example, in one embodiment, the present invention provides a guidewire having a super elastic core wire surrounded by a shape memory polymer jacket. The super elastic core wire permits the guidewire to be navigated through tortuous vasculature without undergoing plastic deformation, and the shape memory polymer jacket permits the guidewire to be shapeable.
-
FIG. 1 is a plan view of a guidewire according to the present invention, in combination with a balloon catheter; -
FIG. 2 is a foreshortened longitudinal cross-sectional view of a distal portion of a guidewire of the present invention, showing a polymer jacket surrounding a distal tip of a core wire; -
FIG. 3 is a foreshortened longitudinal cross-sectional view of a portion of a guidewire of the present invention, showing a polymer jacket surrounding a mid portion of a core wire; and -
FIGS. 4 and 5 are side views of a distal tip portion of a guide wire showing a polymer jacket surrounding a distal portion of a spring tip and core wire, wherein the distal tip is deformed about a cylinder-shaped object. - The following detailed description should be read with reference to the drawings in which similar elements in different drawings are numbered the same. The detailed description and the drawings, which are not necessarily to scale, depict illustrative embodiments and are not intended to limit the scope of the invention.
- Refer now to
FIG. 1 which illustrates a plan view of aguidewire 10 in combination with anintravascular device 100. In this particular example, theintravascular device 100 comprises a balloon catheter, but those skilled in the art will recognize that guidewires may be used alone or in combination with a wide variety of intravascular devices for coronary, peripheral and cerebral use, including balloon catheters, guide catheters, diagnostic catheters, micro-catheters, etc. For purposes of illustration only,intravascular device 100 is shown to be aballoon catheter 100 having anelongate shaft 102, a proximally disposedmanifold 104, and a distally disposedinflatable balloon 106, all of which are conventional in the art. Guidewire 10 may extend through the entire length of theballoon catheter 100, and includes aproximal end 12 and adistal tip portion 14. Theguidewire 10 may have a size (length and diameter) to navigate coronary, peripheral and/or cerebral vasculature, depending on the particular clinical application, and thedistal tip portion 14 may be shaped to facilitate steering in such vascular anatomy. - As seen in
FIG. 2 , theguidewire 10 may include acore wire 20 with apolymer jacket 50 surrounding adistal tip portion 14 thereof. Alternatively, thepolymer jacket 50 may surround a mid portion of theguidewire 10 as shown inFIG. 3 . As shown inFIGS. 4 and 5 , aradiopaque coil 40 may surround adistal portion 14 of thecore wire 20, with adistal weld 42 connecting the distal end of thecoil 40 to the distal end of the core wire 20 (not visible inFIGS. 4 and 5 ). In this latter instance, thepolymer jacket 50 may surround thecore wire 20 and theradiopaque coil 40. As a further alternative, thepolymer jacket 50 may surround an inner polymer jacket (not shown) disposed on thecore wire 20, resulting in a multi-layered polymer jacket arrangement, with layer thicknesses that may vary, but preferably do not exceed the proximal profile of the guidewire. In all embodiments, thepolymer jacket 50 may incorporate radiopaque filler. - In all embodiments illustrated, the
polymer jacket 50 may surround thecore wire 20 and/orradiopaque coil 40 to establish contact therebetween or to establish an annular space therebetween. In addition, thepolymer jacket 50 may surround and encase thecore wire 20 and/orradiopaque coil 40 to encase thedistal tip 14 as shown inFIGS. 2 , 4 and 5, or merely surround a portion thereof without encasing as shown inFIG. 3 . -
Core wire 20 may comprise a stainless steel metal or a super elastic metal such as nitinol (nickel titanium alloy) for purposes of navigating tortuous vasculature without causing plastic deformation thereof.Polymer jacket 50 may comprise a polymer and may have suitable dimensions and material characteristics that render thepolymer jacket 50 more stiff than thedistal tip portion 14 of the superelastic core wire 20 which it surrounds. As used herein, stiff or stiffness refers to the collective property defined by material characteristics and shape, as conventionally used in mechanical engineering design. In particular, the cross-sectional bending moment and the flexural modulus of thepolymer jacket 50 may be selected such that when thetip 14 is deformed into a shape within the elastic limit of the superelastic core wire 20, and beyond the elastic limit of the polymer, thetip 14 substantially retains the shape, although some recoil may occur. - The
polymer jacket 50 may comprise a shape memory polymer such as shape memory polyurethane available from Mitsubishi, polynorbornene polymers and copolymers (including blends with polyethylene and KRATON), polycaprolactone or (oligo)caprolactone copolymer, polymethylmethacylate, PLLA or PL/D LA copolymer, PLLA PGA copolymer, PMMA, cross-linked polyethylene, cross-linked polyisoprene, polycyclooctene, styrene-butadiene copolymer, or photocrosslinkable polymer including azo-dye, zwitterionic and other photoschromic materials (as referenced in Shape memory Materials, Otsuka and Wayman, Cambridge University press, ©1998). - With a shape memory polymer, the
distal tip 14, includingpolymer jacket 50,core wire 20, and/orradiopaque coil 40, may be deformed into the desired shape. By way of example, not limitation, thedistal tip portion 14 may be deformed about acylindrical object 90 to impart a J-tip shape as shown inFIG. 4 , or a bent-L shape as shown inFIG. 5 . Although only basic shapes are shown, it is contemplated that a wide variety of simple and complex shapes may be achieved with the present invention. While the desired shape is maintained, thepolymer jacket 50 may be subjected to heat at a temperature at or above the glass transition temperature (or near the melt temperature) of the shape memory polymer, and subsequently cooled to a temperature below the glass transition temperature. Once cooled, thedistal tip 14 may be released from the constrained shape. The glass transition temperature is preferably greater than the temperature of the environment whereguidewire 10 will be used (i.e., the internal body temperature of a patient), so as to sustain the desired shape whileguidewire 10 is used (e.g., navigated through a vessel lumen of a patient). In other words, the temperature of the environment where guidewire 10 will be used is lower than the glass transition temperature that will allowpolymer jacket 50 to change shape. - After releasing the
distal tip 14 from the constrained shape, the elastic forces of the superelastic core wire 20 work against thepolymer jacket 50, biasing the shape of the distal tip back to the original (e.g., straight) configuration. However, thepolymer jacket 50 has sufficient stiffness, by virtue of its size and its material properties, to substantially oppose, if not completely offset, the biasing force of the superelastic core wire 20. The biasing force of thecore wire 20 may be reduced by reducing the size (e.g., diameter) thereof, and the opposing force of thepolymer jacket 50 may be increased by increasing the size (cross-sectional area moment) and/or the flexural modulus thereof Thus, by substantially opposing, if not completely offsetting, the biasing force of the superelastic core wire 20, thepolymer jacket 50 substantially maintains the deformed shape, although some recoil may occur. To compensate for such recoil, the deformed shape may be exaggerated relative to the desired final shape. - The
distal tip 14 may be re-shaped by re-deforming thedistal tip 14 and exposing thepolymer jacket 50 to heat at a temperature at or above the glass transition temperature (or near the melt temperature) of the shape memory polymer, and subsequently cooled to a temperature below the glass transition temperature. The original (e.g., straight) configuration of thedistal tip 14 may be recaptured by exposing thepolymer jacket 50 to heat at a temperature at or above the transformation temperature of the shape memory polymer, followed by cooling. Thedistal tip 14 may be repeatedly shaped without compromising shapeability or guidewire performance. - The
polymer jacket 50 may surround thedistal tip portion 14 as shown inFIG. 2 or a mid portion of thecore wire 20 as shown inFIG. 3 . To accommodate thepolymer jacket 50 and to provide a uniform outer profile, thecore wire 20 may be ground to have a single taper or a series of tapers as shown inFIG. 2 or ground to define a recess as shown inFIG. 3 . - In
FIG. 2 , thedistal portion 14 of thecore wire 20 includes a series of tapers to accommodate thepolymer jacket 50 and to provide a gradual reduction in stiffness toward the distal end thereof. For example, thecore wire 20 may have a proximaluniform diameter portion 22 having a diameter of about 0.007 to 0.038 inches and a length “A” of about 100 to 260 cm, a miduniform diameter portion 26 having a diameter of about 0.003 to 0.010 inches and a length “C” of about 5 to 30 cm, and a distaluniform diameter portion 30 having a diameter of about 0.0015 to 0.005 inches and a length “E” of about 5 to 30 cm. Alternatively,distal portion 30 may comprise a flat ribbon having a thickness of 0.0015 to 0.005 inches. Thecore wire 20 may also includetapered portions 24/28 between theuniform diameter portions 22/26/30, having tapering diameters and lengths “B” and “D” of about 0.1 to 10 cm to provide a smooth transition between theuniform diameter portions 22/26/30. As an alternative, thecore wire 20 may have a continuous taper terminating in a radiopaque tip, and covered by thepolymer jacket 50. - In
FIG. 3 , a mid portion (i.e., a portion that is proximal of the distal end and distal of the proximal end) of thecore wire 20 is provided with an optional recess having auniform diameter portion 34 and twotapered portions 32/36. The position of therecess 34 and thus the position of thepolymer jacket 50 in this embodiment is dictated by the length “F” of the proximaluniform diameter portion 22 and the length “J” of the distaluniform diameter portion 38. The length “H” of therecess portion 34 may be selected depending on the desired shapeable length of thecore wire 20. The lengths “G” and “I” of the taperedportion 32/36 may be the same or similar to that of taperedportions 24/28 described previously. - Those skilled in the art will recognize that the present invention may be manifested in a variety of forms other than the specific embodiments described and contemplated herein. Accordingly, departures in form and detail may be made without departing from the scope and spirit of the present invention as described in the appended claims.
Claims (20)
1. A method of manufacturing an intravascular guidewire selectively shapeable by a user, the method comprising:
providing an elongate core wire having a distal tip portion;
surrounding the distal tip portion with a polymer jacket, the polymer comprising a shape memory polymer;
deforming the distal tip portion and the polymer jacket into a desired position;
heating the polymer jacket to a temperature at or above a glass transition temperature of the polymer;
cooling the polymer jacket;
releasing the distal tip portion and the polymer jacket.
2. The method of claim 1 , wherein the elongate core wire comprises a super elastic metal.
3. The method of claim 2 , wherein the elongate core wire comprises nitinol.
4. The method of claim 1 , wherein the elongate core wire comprises stainless steel.
5. The method of claim 1 , further comprising disposing a radiopaque coil about the distal tip portion.
6. The method of claim 5 , further comprising disposing an inner polymer layer over the radiopaque coil.
7. The method of claim 1 , wherein the polymer comprises a material and a thickness sufficient to render the polymer stiffer than the distal tip portion.
8. The method of claim 7 , wherein the polymer jacket substantially retains the deformed shape after the distal tip portion has been released.
9. The method of claim 1 , further comprising:
reheating the polymer jacket to a temperature at or above the glass transition temperature of the shape memory polymer such that the polymer jacket returns to its original shape; and
cooling the polymer jacket to a temperature below the glass transition temperature of the polymer.
10. The method of claim 1 , further comprising:
deforming the distal tip portion and the polymer jacket into a different shape;
reheating the polymer jacket to a temperature at or above the glass transition temperature of the polymer; and
cooling the polymer jacket to a temperature below the glass transition temperature.
11. The method of claim 1 , wherein a portion of the elongate core wire proximal to the distal tip portion includes a recess having a constant diameter portion and two tapered portions.
12. The method of claim 11 , further comprising a shape memory polymer disposed within the recess.
13. A method of manufacturing an intravascular guidewire selectively shapeable by a user, the method comprising:
providing an elongate core wire including a constant diameter portion and a tapered distal tip portion extending distally from the constant diameter portion;
surrounding the distal tip portion with a polymer jacket such that the polymer jacket has an outer diameter similar to the constant diameter portion, the polymer comprising a shape memory polymer;
deforming the distal tip portion and the polymer jacket around an object to impart a J-tip shape;
heating the polymer jacket to a temperature at or above a glass transition temperature of the polymer;
cooling the polymer jacket below the glass transition temperature of the polymer;
releasing the distal tip portion and the polymer jacket to result in a final shape of the distal tip portion and the polymer jacket.
14. The method of claim 13 , wherein the deformed J-tip shape is exaggerated relative to the final shape of the distal tip portion and polymer jacket.
15. The method of claim 13 , wherein the polymer jacket substantially retains the J-tip shape after the distal tip portion and polymer jacket have been released.
16. The method of claim 13 , wherein the distal tip portion comprises a series of tapered portions.
17. The method of claim 13 , wherein the polymer jacket includes a radiopaque filler.
18. The method of claim 13 , further comprising:
reheating the polymer jacket to a temperature at or above the glass transition temperature of the shape memory polymer such that the polymer jacket returns to its original shape; and
cooling the polymer jacket to a temperature below the glass transition temperature of the polymer.
19. The method of claim 13 , further comprising:
deforming the distal tip portion and the polymer jacket into a different shape;
reheating the polymer jacket to a temperature at or above the glass transition temperature of the polymer; and
cooling the polymer jacket to a temperature below the glass transition temperature.
20. A method of manufacturing an intravascular guidewire selectively shapeable by a user, the method comprising:
providing an elongate core wire, formed at least in part of nitinol, the elongate core wire including a constant diameter portion and a tapered distal tip portion extending distally from the constant diameter portion;
surrounding the distal tip portion with a polymer jacket such that the polymer jacket has an outer diameter similar to the constant diameter portion, the polymer comprising a shape memory polymer from a subset of polymers which are characterized by their responsiveness to heating at or above a glass transition temperature of the shape memory polymer to transform the shape memory polymer between a first shape and a second shape;
deforming the distal tip portion and the polymer jacket to impart a desired shape;
heating the polymer jacket to a temperature at or above the glass transition temperature of the polymer;
cooling the polymer jacket to a temperature below the glass transition temperature of the polymer; and
releasing the distal tip portion and the polymer jacket;
wherein after the distal tip portion and polymer jacket have been released, the shape memory polymer overcomes a biasing force of the nitinol wire to substantially maintain the desired shape.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/715,299 US20100159117A1 (en) | 2001-12-18 | 2010-03-01 | Super Elastic Guidewire With Shape Retention Tip |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/025,668 US7670302B2 (en) | 2001-12-18 | 2001-12-18 | Super elastic guidewire with shape retention tip |
US12/715,299 US20100159117A1 (en) | 2001-12-18 | 2010-03-01 | Super Elastic Guidewire With Shape Retention Tip |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/025,668 Continuation US7670302B2 (en) | 2001-12-18 | 2001-12-18 | Super elastic guidewire with shape retention tip |
Publications (1)
Publication Number | Publication Date |
---|---|
US20100159117A1 true US20100159117A1 (en) | 2010-06-24 |
Family
ID=21827394
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/025,668 Expired - Lifetime US7670302B2 (en) | 2001-12-18 | 2001-12-18 | Super elastic guidewire with shape retention tip |
US12/715,299 Abandoned US20100159117A1 (en) | 2001-12-18 | 2010-03-01 | Super Elastic Guidewire With Shape Retention Tip |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/025,668 Expired - Lifetime US7670302B2 (en) | 2001-12-18 | 2001-12-18 | Super elastic guidewire with shape retention tip |
Country Status (8)
Country | Link |
---|---|
US (2) | US7670302B2 (en) |
EP (1) | EP1455880B1 (en) |
JP (1) | JP4276543B2 (en) |
AT (1) | ATE457767T1 (en) |
AU (1) | AU2002327057A1 (en) |
CA (1) | CA2469195C (en) |
DE (1) | DE60235401D1 (en) |
WO (1) | WO2003051444A1 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080173391A1 (en) * | 2000-12-28 | 2008-07-24 | Boston Scientific Scimed, Inc. | Method of manufacturing a guidewire with an extrusion jacket |
US20130046376A1 (en) * | 2011-06-24 | 2013-02-21 | Ali Hassan | Method and devices for flow occlusion during device exchanges |
WO2014143762A2 (en) | 2013-03-15 | 2014-09-18 | Armour Technologies, Inc. | Medical device curving apparatus, system, and method of use |
US20140276224A1 (en) * | 2013-03-13 | 2014-09-18 | St. Jude Medical Systems Ab | Sensor guide wire with shape memory tip |
WO2016182791A1 (en) * | 2015-05-14 | 2016-11-17 | Cook Medical Technologies, LLC | Endoscopic needle stylet with enhanced-flexibility lengths |
US9532785B2 (en) | 2012-05-09 | 2017-01-03 | Access Closure, Inc. | Method and devices for flow occlusion during device exchanges |
US10434292B2 (en) | 2011-06-24 | 2019-10-08 | Access Closure | Method and devices for flow occlusion during device exchanges |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7976936B2 (en) * | 2002-10-11 | 2011-07-12 | University Of Connecticut | Endoprostheses |
US7794494B2 (en) * | 2002-10-11 | 2010-09-14 | Boston Scientific Scimed, Inc. | Implantable medical devices |
ES2373650T3 (en) * | 2002-10-11 | 2012-02-07 | University Of Connecticut | RETICULATED POLYCYCLOOCENE. |
US20040167438A1 (en) * | 2003-02-26 | 2004-08-26 | Sharrow James S. | Reinforced medical device |
EP1648548B1 (en) * | 2003-07-18 | 2008-06-11 | Boston Scientific Limited | Medical devices |
US7749242B2 (en) | 2004-06-21 | 2010-07-06 | Boston Scientific Scimed, Inc. | Expanding vaso-occlusive device |
US20060155323A1 (en) | 2005-01-07 | 2006-07-13 | Porter Stephen C | Intra-aneurysm devices |
US20060178697A1 (en) | 2005-02-04 | 2006-08-10 | Carr-Brendel Victoria E | Vaso-occlusive devices including non-biodegradable biomaterials |
US8784336B2 (en) | 2005-08-24 | 2014-07-22 | C. R. Bard, Inc. | Stylet apparatuses and methods of manufacture |
US8388546B2 (en) | 2006-10-23 | 2013-03-05 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
US7794407B2 (en) | 2006-10-23 | 2010-09-14 | Bard Access Systems, Inc. | Method of locating the tip of a central venous catheter |
EP2121100A2 (en) | 2007-02-08 | 2009-11-25 | C.R.Bard, Inc. | Shape memory medical device and methods of manufacturing |
US10751509B2 (en) | 2007-11-26 | 2020-08-25 | C. R. Bard, Inc. | Iconic representations for guidance of an indwelling medical device |
US8781555B2 (en) | 2007-11-26 | 2014-07-15 | C. R. Bard, Inc. | System for placement of a catheter including a signal-generating stylet |
ES2651898T3 (en) | 2007-11-26 | 2018-01-30 | C.R. Bard Inc. | Integrated system for intravascular catheter placement |
US9521961B2 (en) | 2007-11-26 | 2016-12-20 | C. R. Bard, Inc. | Systems and methods for guiding a medical instrument |
US9456766B2 (en) | 2007-11-26 | 2016-10-04 | C. R. Bard, Inc. | Apparatus for use with needle insertion guidance system |
US10524691B2 (en) | 2007-11-26 | 2020-01-07 | C. R. Bard, Inc. | Needle assembly including an aligned magnetic element |
US8849382B2 (en) | 2007-11-26 | 2014-09-30 | C. R. Bard, Inc. | Apparatus and display methods relating to intravascular placement of a catheter |
US9649048B2 (en) | 2007-11-26 | 2017-05-16 | C. R. Bard, Inc. | Systems and methods for breaching a sterile field for intravascular placement of a catheter |
US10449330B2 (en) | 2007-11-26 | 2019-10-22 | C. R. Bard, Inc. | Magnetic element-equipped needle assemblies |
US8478382B2 (en) | 2008-02-11 | 2013-07-02 | C. R. Bard, Inc. | Systems and methods for positioning a catheter |
US20090275862A1 (en) * | 2008-04-30 | 2009-11-05 | Cook Incorporated | Guidewire and method of making same |
US9901714B2 (en) | 2008-08-22 | 2018-02-27 | C. R. Bard, Inc. | Catheter assembly including ECG sensor and magnetic assemblies |
JP5677955B2 (en) | 2008-09-09 | 2015-02-25 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | Combined desorption mechanism |
US8437833B2 (en) | 2008-10-07 | 2013-05-07 | Bard Access Systems, Inc. | Percutaneous magnetic gastrostomy |
CN102639303B (en) | 2008-12-08 | 2015-09-30 | 血管科学有限公司 | For forming micro-cutting machine of otch in the product |
US11406791B2 (en) | 2009-04-03 | 2022-08-09 | Scientia Vascular, Inc. | Micro-fabricated guidewire devices having varying diameters |
US10363389B2 (en) | 2009-04-03 | 2019-07-30 | Scientia Vascular, Llc | Micro-fabricated guidewire devices having varying diameters |
US20100249655A1 (en) * | 2009-03-30 | 2010-09-30 | C. R. Bard, Inc. | Tip-Shapeable Guidewire |
US9950137B2 (en) | 2009-04-03 | 2018-04-24 | Scientia Vascular, Llc | Micro-fabricated guidewire devices formed with hybrid materials |
US9125578B2 (en) | 2009-06-12 | 2015-09-08 | Bard Access Systems, Inc. | Apparatus and method for catheter navigation and tip location |
US9532724B2 (en) | 2009-06-12 | 2017-01-03 | Bard Access Systems, Inc. | Apparatus and method for catheter navigation using endovascular energy mapping |
ES2745861T3 (en) | 2009-06-12 | 2020-03-03 | Bard Access Systems Inc | Apparatus, computer-aided data-processing algorithm, and computer storage medium for positioning an endovascular device in or near the heart |
EP2464407A4 (en) | 2009-08-10 | 2014-04-02 | Bard Access Systems Inc | Devices and methods for endovascular electrography |
US20110066029A1 (en) * | 2009-09-11 | 2011-03-17 | Medtronic, Inc. | Electromagnetic Medical Device |
WO2011041450A1 (en) | 2009-09-29 | 2011-04-07 | C. R. Bard, Inc. | Stylets for use with apparatus for intravascular placement of a catheter |
US11103213B2 (en) | 2009-10-08 | 2021-08-31 | C. R. Bard, Inc. | Spacers for use with an ultrasound probe |
EP3662827B1 (en) | 2010-05-28 | 2021-03-03 | C.R. Bard, Inc. | Apparatus for use with needle insertion guidance system |
CN103228219B (en) | 2010-08-09 | 2016-04-27 | C·R·巴德股份有限公司 | For support and the covered structure of ultrasound probe head |
KR101856267B1 (en) | 2010-08-20 | 2018-05-09 | 씨. 알. 바드, 인크. | Reconfirmation of ecg-assisted catheter tip placement |
WO2012058461A1 (en) | 2010-10-29 | 2012-05-03 | C.R.Bard, Inc. | Bioimpedance-assisted placement of a medical device |
US20120271409A1 (en) * | 2011-04-25 | 2012-10-25 | Medtronic Vascular, Inc. | Helical Radiopaque Marker |
RU2609203C2 (en) | 2011-07-06 | 2017-01-30 | Си.Ар. Бард, Инк. | Determination and calibration of needle length for needle guidance system |
USD699359S1 (en) | 2011-08-09 | 2014-02-11 | C. R. Bard, Inc. | Ultrasound probe head |
USD724745S1 (en) | 2011-08-09 | 2015-03-17 | C. R. Bard, Inc. | Cap for an ultrasound probe |
WO2013070775A1 (en) | 2011-11-07 | 2013-05-16 | C.R. Bard, Inc | Ruggedized ultrasound hydrogel insert |
US20130304108A1 (en) * | 2012-05-08 | 2013-11-14 | Daniel C. Weber | Systems and apparatus for treating blood vessels and related methods |
US10820885B2 (en) | 2012-06-15 | 2020-11-03 | C. R. Bard, Inc. | Apparatus and methods for detection of a removable cap on an ultrasound probe |
CN105517618A (en) * | 2013-07-03 | 2016-04-20 | 波士顿科学国际有限公司 | Guidewire |
US9646599B2 (en) * | 2013-10-24 | 2017-05-09 | Spirit Aerosystems, Inc. | Remoldable contour sensor holder |
ES2811323T3 (en) | 2014-02-06 | 2021-03-11 | Bard Inc C R | Systems for the guidance and placement of an intravascular device |
US20160101267A1 (en) * | 2014-10-14 | 2016-04-14 | Sanford Health | Anchoring Device and Methods for Use |
US10973584B2 (en) | 2015-01-19 | 2021-04-13 | Bard Access Systems, Inc. | Device and method for vascular access |
CN107529989B (en) * | 2015-04-14 | 2023-08-04 | 皇家飞利浦有限公司 | Intravascular devices, systems, and methods of formation |
WO2016210325A1 (en) | 2015-06-26 | 2016-12-29 | C.R. Bard, Inc. | Connector interface for ecg-based catheter positioning system |
US11000207B2 (en) | 2016-01-29 | 2021-05-11 | C. R. Bard, Inc. | Multiple coil system for tracking a medical device |
JP2019508218A (en) | 2016-03-18 | 2019-03-28 | テレフレックス イノベーションズ エス.アー.エール.エル. | Pacing guidewire |
US11207502B2 (en) | 2016-07-18 | 2021-12-28 | Scientia Vascular, Llc | Guidewire devices having shapeable tips and bypass cuts |
US11052228B2 (en) | 2016-07-18 | 2021-07-06 | Scientia Vascular, Llc | Guidewire devices having shapeable tips and bypass cuts |
US10821268B2 (en) | 2016-09-14 | 2020-11-03 | Scientia Vascular, Llc | Integrated coil vascular devices |
CN106420009B (en) * | 2016-10-31 | 2023-07-28 | 上海瑞柯恩激光技术有限公司 | Tissue grinder cutter head and laser treatment device |
US11452541B2 (en) | 2016-12-22 | 2022-09-27 | Scientia Vascular, Inc. | Intravascular device having a selectively deflectable tip |
ES2869148T3 (en) | 2017-05-26 | 2021-10-25 | Scientia Vascular Llc | Microfabricated medical device with a non-helical cutting arrangement |
US11305095B2 (en) | 2018-02-22 | 2022-04-19 | Scientia Vascular, Llc | Microfabricated catheter having an intermediate preferred bending section |
WO2020081373A1 (en) | 2018-10-16 | 2020-04-23 | Bard Access Systems, Inc. | Safety-equipped connection systems and methods thereof for establishing electrical connections |
KR102136253B1 (en) * | 2018-12-24 | 2020-07-22 | 윤주영 | Cable cover composition having flame resistance and antistatic properties, and cable cover using the same |
CN114214842B (en) * | 2021-12-22 | 2022-10-21 | 江南大学 | Double-pass shape memory fiber with photoelectric stimulation response and preparation method thereof |
Citations (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3467102A (en) * | 1967-04-18 | 1969-09-16 | Edwards Lab Inc | Leader type catheter |
US4385635A (en) * | 1980-04-25 | 1983-05-31 | Ruiz Oscar F | Angiographic catheter with soft tip end |
US4430083A (en) * | 1981-03-06 | 1984-02-07 | American Hospital Supply Corporation | Infusion catheter |
US4547193A (en) * | 1984-04-05 | 1985-10-15 | Angiomedics Incorporated | Catheter having embedded multi-apertured film |
US4569347A (en) * | 1984-05-30 | 1986-02-11 | Advanced Cardiovascular Systems, Inc. | Catheter introducing device, assembly and method |
US4690175A (en) * | 1981-11-17 | 1987-09-01 | Kabushiki Kaisha Medos Kenkyusho | Flexible tube for endoscope |
US4801297A (en) * | 1984-06-01 | 1989-01-31 | Edward Weck Incorporated | Catheter having slit tip |
US4925445A (en) * | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
US4960410A (en) * | 1989-03-31 | 1990-10-02 | Cordis Corporation | Flexible tubular member for catheter construction |
US4998923A (en) * | 1988-08-11 | 1991-03-12 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US5069226A (en) * | 1989-04-28 | 1991-12-03 | Tokin Corporation | Catheter guidewire with pseudo elastic shape memory alloy |
US5095915A (en) * | 1990-03-19 | 1992-03-17 | Target Therapeutics | Guidewire with flexible distal tip |
US5114402A (en) * | 1983-10-31 | 1992-05-19 | Catheter Research, Inc. | Spring-biased tip assembly |
US5180376A (en) * | 1990-05-01 | 1993-01-19 | Cathco, Inc. | Non-buckling thin-walled sheath for the percutaneous insertion of intraluminal catheters |
US5213111A (en) * | 1991-07-10 | 1993-05-25 | Cook Incorporated | Composite wire guide construction |
US5364357A (en) * | 1989-09-25 | 1994-11-15 | Schneider (Usa) Inc. | Small diameter dilatation catheter having wire reinforced coaxial tubular body |
US5368049A (en) * | 1991-05-21 | 1994-11-29 | C. R. Bard, Inc. | Superelastic formable guidewire with malleable cladding |
US5381782A (en) * | 1992-01-09 | 1995-01-17 | Spectrum Medsystems Corporation | Bi-directional and multi-directional miniscopes |
US5409015A (en) * | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US5437288A (en) * | 1992-09-04 | 1995-08-01 | Mayo Foundation For Medical Education And Research | Flexible catheter guidewire |
US5443455A (en) * | 1993-07-27 | 1995-08-22 | Target Therapeutics, Inc. | Guidewire and method of pretreating metal surfaces for subsequent polymer coating |
US5452726A (en) * | 1991-06-18 | 1995-09-26 | Scimed Life Systems, Inc. | Intravascular guide wire and method for manufacture thereof |
US5454787A (en) * | 1991-02-15 | 1995-10-03 | Lundquist; Ingemar H. | Torquable tubular assembly and torquable catheter utilizing the same |
US5456665A (en) * | 1994-03-04 | 1995-10-10 | Arrow International Investment Corp. | Intra-aortic balloon catheter |
US5458605A (en) * | 1994-04-04 | 1995-10-17 | Advanced Cardiovascular Systems, Inc. | Coiled reinforced retractable sleeve for stent delivery catheter |
US5507766A (en) * | 1993-01-26 | 1996-04-16 | Terumo Kabushiki Kaisha | Vascular dilatation instrument and catheter |
US5531719A (en) * | 1993-06-29 | 1996-07-02 | Terumo Kabushiki Kaisha | Vascular catheter with helical space |
US5542434A (en) * | 1994-10-28 | 1996-08-06 | Intelliwire Inc. | Guide wire with deflectable tip and method |
US5546958A (en) * | 1994-03-31 | 1996-08-20 | Lake Region Manufacturing Company, Inc. | Guidewire extension system with tactile connection indication |
US5569200A (en) * | 1994-06-20 | 1996-10-29 | Terumo Kabushiki Kaisha | Vascular catheter |
US5573520A (en) * | 1991-09-05 | 1996-11-12 | Mayo Foundation For Medical Education And Research | Flexible tubular device for use in medical applications |
US5596996A (en) * | 1995-03-30 | 1997-01-28 | Medtronic, Inc. | High support nitinol tube guidewire with plastic plug transition |
US5662621A (en) * | 1995-07-06 | 1997-09-02 | Scimed Life Systems, Inc. | Guide catheter with shape memory retention |
US5716410A (en) * | 1993-04-30 | 1998-02-10 | Scimed Life Systems, Inc. | Temporary stent and method of use |
US5722424A (en) * | 1995-09-29 | 1998-03-03 | Target Therapeutics, Inc. | Multi-coating stainless steel guidewire |
US5741429A (en) * | 1991-09-05 | 1998-04-21 | Cardia Catheter Company | Flexible tubular device for use in medical applications |
US5749837A (en) * | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
US5762630A (en) * | 1996-12-23 | 1998-06-09 | Johnson & Johnson Medical, Inc. | Thermally softening stylet |
US5769796A (en) * | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
US5772609A (en) * | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
US5776100A (en) * | 1995-09-27 | 1998-07-07 | Interventional Innovations Corporation | Nickel titanium guide wires for occlusion and drug delivery |
US5780807A (en) * | 1994-11-28 | 1998-07-14 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for direct laser cutting of metal stents |
US5814063A (en) * | 1994-12-23 | 1998-09-29 | Willy Rusch Ag | Stent for placement in a body tube |
US5814705A (en) * | 1985-01-04 | 1998-09-29 | Thoratec Laboratories Corporation | Compositions that soften at predetermined temperatures and the method of making same |
US5827201A (en) * | 1996-07-26 | 1998-10-27 | Target Therapeutics, Inc. | Micro-braided guidewire |
US5833632A (en) * | 1995-12-07 | 1998-11-10 | Sarcos, Inc. | Hollow guide wire apparatus catheters |
US5836303A (en) * | 1996-09-17 | 1998-11-17 | Thermal Air Products, Inc. | Respirator apparatus |
US5836893A (en) * | 1996-03-08 | 1998-11-17 | Scimed Life Systems, Inc. | Intravascular guidewire |
US5843050A (en) * | 1995-11-13 | 1998-12-01 | Micro Therapeutics, Inc. | Microcatheter |
US5843031A (en) * | 1994-10-24 | 1998-12-01 | Medtronic, Inc. | Large-diameter introducer sheath having hemostasis valve and removable steering mechanism |
US5860938A (en) * | 1996-03-07 | 1999-01-19 | Scimed Life Systems, Inc. | Medical pressure sensing guide wire |
US5916178A (en) * | 1995-03-30 | 1999-06-29 | Medtronic, Inc. | Steerable high support guidewire with thin wall nitinol tube |
US5921956A (en) * | 1997-09-24 | 1999-07-13 | Smith & Nephew, Inc. | Surgical instrument |
US5938623A (en) * | 1994-10-28 | 1999-08-17 | Intella Interventional Systems | Guide wire with adjustable stiffness |
US5944701A (en) * | 1996-10-03 | 1999-08-31 | Dubrul; William R. | Self coiling catheter |
US5957966A (en) * | 1998-02-18 | 1999-09-28 | Intermedics Inc. | Implantable cardiac lead with multiple shape memory polymer structures |
US5964714A (en) * | 1996-03-07 | 1999-10-12 | Scimed Life Systems, Inc. | Pressure sensing guide wire |
US6001068A (en) * | 1996-10-22 | 1999-12-14 | Terumo Kabushiki Kaisha | Guide wire having tubular connector with helical slits |
US6019736A (en) * | 1995-11-06 | 2000-02-01 | Francisco J. Avellanet | Guidewire for catheter |
US6024764A (en) * | 1997-08-19 | 2000-02-15 | Intermedics, Inc. | Apparatus for imparting physician-determined shapes to implantable tubular devices |
US6059815A (en) * | 1997-02-28 | 2000-05-09 | The Regents Of The University Of California | Microfabricated therapeutic actuators and release mechanisms therefor |
US6090072A (en) * | 1992-10-15 | 2000-07-18 | Scimed Life Systems, Inc. | Expandable introducer sheath |
US6096012A (en) * | 1996-08-27 | 2000-08-01 | Johnson & Johnson Medical, Inc. | Coated one-piece composite plastic catheter and cannula |
US6099485A (en) * | 1996-08-27 | 2000-08-08 | C. R. Bard, Inc. | Torquable, low mass medical guidewire |
US6139510A (en) * | 1994-05-11 | 2000-10-31 | Target Therapeutics Inc. | Super elastic alloy guidewire |
US6146339A (en) * | 1999-05-24 | 2000-11-14 | Advanced Cardiovascular Systems | Guide wire with operator controllable tip stiffness |
US6156842A (en) * | 1998-03-11 | 2000-12-05 | The Dow Chemical Company | Structures and fabricated articles having shape memory made from α-olefin/vinyl or vinylidene aromatic and/or hindered aliphatic vinyl or vinylidene interpolymers |
US6160084A (en) * | 1998-02-23 | 2000-12-12 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
US6168604B1 (en) * | 1995-10-06 | 2001-01-02 | Metamorphic Surgical Devices, Llc | Guide wire device for removing solid objects from body canals |
US6181136B1 (en) * | 1997-10-24 | 2001-01-30 | Electronics And Telecommunications Research Institute | Method of manufacturing the human tissue phantoms for evaluation of electromagnetic wave environment |
US20010009980A1 (en) * | 1998-12-30 | 2001-07-26 | Edward J. Lynch | Guidewire with multiple polymer jackets over distal and intermediate core sections |
US20020068968A1 (en) * | 2000-08-16 | 2002-06-06 | Thomas Hupp | Virtual stent making process based upon novel enhanced plate tectonics derived from endoluminal mapping |
US20020165478A1 (en) * | 2001-05-02 | 2002-11-07 | Morteza Gharib | Bifurcatable trabecular shunt for glaucoma treatment |
US6485458B1 (en) * | 1999-01-27 | 2002-11-26 | Johnson & Johnson Kabushiki Kaisha | Surgical insertion instrument body having a distending portion |
US20020183654A1 (en) * | 2001-05-30 | 2002-12-05 | Scimed Life Systems, Inc. | Distal tip portion for a guide wire |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3467101A (en) | 1965-09-30 | 1969-09-16 | Edwards Lab Inc | Balloon catheter |
US4464176A (en) | 1982-06-04 | 1984-08-07 | Mallinckrodt, Inc. | Blood vessel catheter for medicine delivery and method of manufacture |
DE3650342T2 (en) * | 1985-01-04 | 1995-11-02 | Thoratec Lab Corp | Process for producing a molded part with shape memory properties and some of these molded parts obtained. |
JPS63238872A (en) | 1987-03-25 | 1988-10-04 | テルモ株式会社 | Instrument for securing inner diameter of cavity of tubular organ and catheter equipped therewith |
US4985022A (en) | 1988-11-23 | 1991-01-15 | Med Institute, Inc. | Catheter having durable and flexible segments |
JPH0333809A (en) * | 1989-06-30 | 1991-02-14 | Showa Electric Wire & Cable Co Ltd | Coated optical fiber |
JP2528011B2 (en) | 1989-12-20 | 1996-08-28 | テルモ株式会社 | Catheter |
DE4104092A1 (en) | 1990-02-13 | 1991-08-14 | Christoph Dr Med Rieger | Metal cannula enclosed in outer cannula of flexible plastics - has circumferential slots in wall to increase flexibility |
US6027863A (en) | 1991-09-05 | 2000-02-22 | Intratherapeutics, Inc. | Method for manufacturing a tubular medical device |
ATE169233T1 (en) | 1991-09-05 | 1998-08-15 | Mayo Foundation | FLEXIBLE TUBULAR DEVICE FOR MEDICAL APPLICATIONS |
JP3277545B2 (en) * | 1992-03-19 | 2002-04-22 | 日本ゼオン株式会社 | Hemostatic sheath with hemostatic valve |
JP3310031B2 (en) | 1992-10-23 | 2002-07-29 | テルモ株式会社 | Catheter tube |
EP0608853B1 (en) | 1993-01-26 | 2003-04-02 | Terumo Kabushiki Kaisha | Vascular dilatation instrument and catheter |
FR2713492B1 (en) | 1993-12-09 | 1996-02-16 | Microfil Ind Sa | Adjustable tubular guide, in particular for a medical and surgical device. |
IL116161A0 (en) * | 1994-11-29 | 1996-01-31 | Target Therapeutics Inc | Lubricious guidewire |
JPH08257128A (en) | 1995-03-24 | 1996-10-08 | Piolax Inc | Medical tube |
CA2192045A1 (en) | 1995-12-07 | 1997-06-08 | Stephen C. Jacobsen | Catheter guide wire apparatus |
JPH10216238A (en) * | 1997-02-05 | 1998-08-18 | Mitsubishi Cable Ind Ltd | Bending mechanism |
AU8764998A (en) | 1997-09-04 | 1999-03-22 | Alcon Laboratories, Inc. | Flexible tube with circular grooves of varying width and depth |
US6340441B1 (en) | 1998-03-13 | 2002-01-22 | Scimed Life Systems, Inc. | Multi-layer guide wire and method of manufacture therefor |
AUPQ170799A0 (en) * | 1999-07-20 | 1999-08-12 | Cardiac Crc Nominees Pty Limited | Shape memory polyurethane or polyurethane-urea polymers |
-
2001
- 2001-12-18 US US10/025,668 patent/US7670302B2/en not_active Expired - Lifetime
-
2002
- 2002-09-25 JP JP2003552373A patent/JP4276543B2/en not_active Expired - Lifetime
- 2002-09-25 AU AU2002327057A patent/AU2002327057A1/en not_active Abandoned
- 2002-09-25 DE DE60235401T patent/DE60235401D1/en not_active Expired - Lifetime
- 2002-09-25 EP EP02761822A patent/EP1455880B1/en not_active Expired - Lifetime
- 2002-09-25 WO PCT/US2002/030402 patent/WO2003051444A1/en active Application Filing
- 2002-09-25 AT AT02761822T patent/ATE457767T1/en not_active IP Right Cessation
- 2002-09-25 CA CA2469195A patent/CA2469195C/en not_active Expired - Lifetime
-
2010
- 2010-03-01 US US12/715,299 patent/US20100159117A1/en not_active Abandoned
Patent Citations (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3467102A (en) * | 1967-04-18 | 1969-09-16 | Edwards Lab Inc | Leader type catheter |
US4385635A (en) * | 1980-04-25 | 1983-05-31 | Ruiz Oscar F | Angiographic catheter with soft tip end |
US4430083A (en) * | 1981-03-06 | 1984-02-07 | American Hospital Supply Corporation | Infusion catheter |
US4690175A (en) * | 1981-11-17 | 1987-09-01 | Kabushiki Kaisha Medos Kenkyusho | Flexible tube for endoscope |
US4925445A (en) * | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
US5114402A (en) * | 1983-10-31 | 1992-05-19 | Catheter Research, Inc. | Spring-biased tip assembly |
US4547193A (en) * | 1984-04-05 | 1985-10-15 | Angiomedics Incorporated | Catheter having embedded multi-apertured film |
US4569347A (en) * | 1984-05-30 | 1986-02-11 | Advanced Cardiovascular Systems, Inc. | Catheter introducing device, assembly and method |
US4801297A (en) * | 1984-06-01 | 1989-01-31 | Edward Weck Incorporated | Catheter having slit tip |
US5814705A (en) * | 1985-01-04 | 1998-09-29 | Thoratec Laboratories Corporation | Compositions that soften at predetermined temperatures and the method of making same |
US4998923A (en) * | 1988-08-11 | 1991-03-12 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US4960410A (en) * | 1989-03-31 | 1990-10-02 | Cordis Corporation | Flexible tubular member for catheter construction |
US5069226A (en) * | 1989-04-28 | 1991-12-03 | Tokin Corporation | Catheter guidewire with pseudo elastic shape memory alloy |
US5364357A (en) * | 1989-09-25 | 1994-11-15 | Schneider (Usa) Inc. | Small diameter dilatation catheter having wire reinforced coaxial tubular body |
US5095915A (en) * | 1990-03-19 | 1992-03-17 | Target Therapeutics | Guidewire with flexible distal tip |
US5180376A (en) * | 1990-05-01 | 1993-01-19 | Cathco, Inc. | Non-buckling thin-walled sheath for the percutaneous insertion of intraluminal catheters |
US5454787A (en) * | 1991-02-15 | 1995-10-03 | Lundquist; Ingemar H. | Torquable tubular assembly and torquable catheter utilizing the same |
US5368049A (en) * | 1991-05-21 | 1994-11-29 | C. R. Bard, Inc. | Superelastic formable guidewire with malleable cladding |
US5452726A (en) * | 1991-06-18 | 1995-09-26 | Scimed Life Systems, Inc. | Intravascular guide wire and method for manufacture thereof |
US6908443B2 (en) * | 1991-06-18 | 2005-06-21 | Scimed Life Systems, Inc. | Intravascular guide wire and method for manufacture thereof |
US5213111A (en) * | 1991-07-10 | 1993-05-25 | Cook Incorporated | Composite wire guide construction |
US5741429A (en) * | 1991-09-05 | 1998-04-21 | Cardia Catheter Company | Flexible tubular device for use in medical applications |
US5573520A (en) * | 1991-09-05 | 1996-11-12 | Mayo Foundation For Medical Education And Research | Flexible tubular device for use in medical applications |
US5381782A (en) * | 1992-01-09 | 1995-01-17 | Spectrum Medsystems Corporation | Bi-directional and multi-directional miniscopes |
US5437288A (en) * | 1992-09-04 | 1995-08-01 | Mayo Foundation For Medical Education And Research | Flexible catheter guidewire |
US6090072A (en) * | 1992-10-15 | 2000-07-18 | Scimed Life Systems, Inc. | Expandable introducer sheath |
US6183443B1 (en) * | 1992-10-15 | 2001-02-06 | Scimed Life Systems, Inc. | Expandable introducer sheath |
US5507766A (en) * | 1993-01-26 | 1996-04-16 | Terumo Kabushiki Kaisha | Vascular dilatation instrument and catheter |
US5716410A (en) * | 1993-04-30 | 1998-02-10 | Scimed Life Systems, Inc. | Temporary stent and method of use |
US5769796A (en) * | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
US5409015A (en) * | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US5636642A (en) * | 1993-05-11 | 1997-06-10 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US5749837A (en) * | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
US5772609A (en) * | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
US5531719A (en) * | 1993-06-29 | 1996-07-02 | Terumo Kabushiki Kaisha | Vascular catheter with helical space |
US5750206A (en) * | 1993-07-27 | 1998-05-12 | Target Therapeutics, Inc. | Method of pretreating metal surfaces for subsequent polymer coating |
US5443455A (en) * | 1993-07-27 | 1995-08-22 | Target Therapeutics, Inc. | Guidewire and method of pretreating metal surfaces for subsequent polymer coating |
US5456665C1 (en) * | 1994-03-04 | 2001-05-22 | Arrow Internat Invest Corp | Intra-aortic balloon catheter |
US5456665A (en) * | 1994-03-04 | 1995-10-10 | Arrow International Investment Corp. | Intra-aortic balloon catheter |
US5546958A (en) * | 1994-03-31 | 1996-08-20 | Lake Region Manufacturing Company, Inc. | Guidewire extension system with tactile connection indication |
US6193706B1 (en) * | 1994-03-31 | 2001-02-27 | Lake Region Manufacturing Co., Inc. | Guidewire extension system with tactile connection indication |
US5458605A (en) * | 1994-04-04 | 1995-10-17 | Advanced Cardiovascular Systems, Inc. | Coiled reinforced retractable sleeve for stent delivery catheter |
US6139510A (en) * | 1994-05-11 | 2000-10-31 | Target Therapeutics Inc. | Super elastic alloy guidewire |
US5569200A (en) * | 1994-06-20 | 1996-10-29 | Terumo Kabushiki Kaisha | Vascular catheter |
US5782809A (en) * | 1994-06-20 | 1998-07-21 | Terumo Kabushiki Kaisha | Vascular catheter |
US5843031A (en) * | 1994-10-24 | 1998-12-01 | Medtronic, Inc. | Large-diameter introducer sheath having hemostasis valve and removable steering mechanism |
US5813997A (en) * | 1994-10-28 | 1998-09-29 | Intelliwire, Inc. | Guide wire with deflectable tip and method |
US5542434A (en) * | 1994-10-28 | 1996-08-06 | Intelliwire Inc. | Guide wire with deflectable tip and method |
US5938623A (en) * | 1994-10-28 | 1999-08-17 | Intella Interventional Systems | Guide wire with adjustable stiffness |
US5780807A (en) * | 1994-11-28 | 1998-07-14 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for direct laser cutting of metal stents |
US5814063A (en) * | 1994-12-23 | 1998-09-29 | Willy Rusch Ag | Stent for placement in a body tube |
US5916178A (en) * | 1995-03-30 | 1999-06-29 | Medtronic, Inc. | Steerable high support guidewire with thin wall nitinol tube |
US5596996A (en) * | 1995-03-30 | 1997-01-28 | Medtronic, Inc. | High support nitinol tube guidewire with plastic plug transition |
US5662621A (en) * | 1995-07-06 | 1997-09-02 | Scimed Life Systems, Inc. | Guide catheter with shape memory retention |
US5776100A (en) * | 1995-09-27 | 1998-07-07 | Interventional Innovations Corporation | Nickel titanium guide wires for occlusion and drug delivery |
US5984878A (en) * | 1995-09-29 | 1999-11-16 | Target Therapeutics, Inc. | Multi-coating stainless steel guidewire |
US5722424A (en) * | 1995-09-29 | 1998-03-03 | Target Therapeutics, Inc. | Multi-coating stainless steel guidewire |
US6168604B1 (en) * | 1995-10-06 | 2001-01-02 | Metamorphic Surgical Devices, Llc | Guide wire device for removing solid objects from body canals |
US6019736A (en) * | 1995-11-06 | 2000-02-01 | Francisco J. Avellanet | Guidewire for catheter |
US5843050A (en) * | 1995-11-13 | 1998-12-01 | Micro Therapeutics, Inc. | Microcatheter |
US5833632A (en) * | 1995-12-07 | 1998-11-10 | Sarcos, Inc. | Hollow guide wire apparatus catheters |
US5860938A (en) * | 1996-03-07 | 1999-01-19 | Scimed Life Systems, Inc. | Medical pressure sensing guide wire |
US5964714A (en) * | 1996-03-07 | 1999-10-12 | Scimed Life Systems, Inc. | Pressure sensing guide wire |
US5836893A (en) * | 1996-03-08 | 1998-11-17 | Scimed Life Systems, Inc. | Intravascular guidewire |
US5827201A (en) * | 1996-07-26 | 1998-10-27 | Target Therapeutics, Inc. | Micro-braided guidewire |
US6099485A (en) * | 1996-08-27 | 2000-08-08 | C. R. Bard, Inc. | Torquable, low mass medical guidewire |
US6096012A (en) * | 1996-08-27 | 2000-08-01 | Johnson & Johnson Medical, Inc. | Coated one-piece composite plastic catheter and cannula |
US5836303A (en) * | 1996-09-17 | 1998-11-17 | Thermal Air Products, Inc. | Respirator apparatus |
US5944701A (en) * | 1996-10-03 | 1999-08-31 | Dubrul; William R. | Self coiling catheter |
US6001068A (en) * | 1996-10-22 | 1999-12-14 | Terumo Kabushiki Kaisha | Guide wire having tubular connector with helical slits |
US5762630A (en) * | 1996-12-23 | 1998-06-09 | Johnson & Johnson Medical, Inc. | Thermally softening stylet |
US6059815A (en) * | 1997-02-28 | 2000-05-09 | The Regents Of The University Of California | Microfabricated therapeutic actuators and release mechanisms therefor |
US6024764A (en) * | 1997-08-19 | 2000-02-15 | Intermedics, Inc. | Apparatus for imparting physician-determined shapes to implantable tubular devices |
US5921956A (en) * | 1997-09-24 | 1999-07-13 | Smith & Nephew, Inc. | Surgical instrument |
US6181136B1 (en) * | 1997-10-24 | 2001-01-30 | Electronics And Telecommunications Research Institute | Method of manufacturing the human tissue phantoms for evaluation of electromagnetic wave environment |
US5957966A (en) * | 1998-02-18 | 1999-09-28 | Intermedics Inc. | Implantable cardiac lead with multiple shape memory polymer structures |
US6160084A (en) * | 1998-02-23 | 2000-12-12 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
US6156842A (en) * | 1998-03-11 | 2000-12-05 | The Dow Chemical Company | Structures and fabricated articles having shape memory made from α-olefin/vinyl or vinylidene aromatic and/or hindered aliphatic vinyl or vinylidene interpolymers |
US20010009980A1 (en) * | 1998-12-30 | 2001-07-26 | Edward J. Lynch | Guidewire with multiple polymer jackets over distal and intermediate core sections |
US6494847B1 (en) * | 1998-12-30 | 2002-12-17 | Advanced Cardiovascular Systems, Inc. | Guide wire with multiple polymer jackets over distal and intermediate core sections |
US6485458B1 (en) * | 1999-01-27 | 2002-11-26 | Johnson & Johnson Kabushiki Kaisha | Surgical insertion instrument body having a distending portion |
US6146339A (en) * | 1999-05-24 | 2000-11-14 | Advanced Cardiovascular Systems | Guide wire with operator controllable tip stiffness |
US20020068968A1 (en) * | 2000-08-16 | 2002-06-06 | Thomas Hupp | Virtual stent making process based upon novel enhanced plate tectonics derived from endoluminal mapping |
US20020165478A1 (en) * | 2001-05-02 | 2002-11-07 | Morteza Gharib | Bifurcatable trabecular shunt for glaucoma treatment |
US20020183654A1 (en) * | 2001-05-30 | 2002-12-05 | Scimed Life Systems, Inc. | Distal tip portion for a guide wire |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080173391A1 (en) * | 2000-12-28 | 2008-07-24 | Boston Scientific Scimed, Inc. | Method of manufacturing a guidewire with an extrusion jacket |
US8535242B2 (en) * | 2000-12-28 | 2013-09-17 | Boston Scientific Scimed, Inc. | Method of manufacturing a guidewire with an extrusion jacket |
US20130344230A1 (en) * | 2000-12-28 | 2013-12-26 | Boston Scientific Scimed, Inc. | Method of manufacturing a guidewire with an extrusion jacket |
US8668657B2 (en) * | 2000-12-28 | 2014-03-11 | Boston Scientific Scimed, Inc. | Method of manufacturing a guidewire with an extrusion jacket |
US20130046376A1 (en) * | 2011-06-24 | 2013-02-21 | Ali Hassan | Method and devices for flow occlusion during device exchanges |
US10434292B2 (en) | 2011-06-24 | 2019-10-08 | Access Closure | Method and devices for flow occlusion during device exchanges |
US9532785B2 (en) | 2012-05-09 | 2017-01-03 | Access Closure, Inc. | Method and devices for flow occlusion during device exchanges |
US20140276224A1 (en) * | 2013-03-13 | 2014-09-18 | St. Jude Medical Systems Ab | Sensor guide wire with shape memory tip |
US10660573B2 (en) * | 2013-03-13 | 2020-05-26 | St. Jude Medical Coordination Center Bvba | Sensor guide wire with shape memory tip |
US9901705B2 (en) | 2013-03-15 | 2018-02-27 | Armour Technologies, Inc. | Medical device curving apparatus, system, and method of use |
WO2014143762A2 (en) | 2013-03-15 | 2014-09-18 | Armour Technologies, Inc. | Medical device curving apparatus, system, and method of use |
US10729878B2 (en) | 2013-03-15 | 2020-08-04 | Armour Technologies, Inc. | Medical device curving apparatus, system, and method of use |
US11040171B2 (en) | 2013-03-15 | 2021-06-22 | Armour Technologies, Inc. | Medical device curving system |
WO2016182791A1 (en) * | 2015-05-14 | 2016-11-17 | Cook Medical Technologies, LLC | Endoscopic needle stylet with enhanced-flexibility lengths |
US10226279B2 (en) | 2015-05-14 | 2019-03-12 | Cook Medical Technologies Llc | Endoscopic needle stylet with enhanced-flexibility lengths |
US10993742B2 (en) | 2015-05-14 | 2021-05-04 | Cook Medical Technologies Llc | Endoscopic needle stylet with enhanced-flexibility lengths |
Also Published As
Publication number | Publication date |
---|---|
CA2469195C (en) | 2011-09-13 |
DE60235401D1 (en) | 2010-04-01 |
EP1455880B1 (en) | 2010-02-17 |
AU2002327057A1 (en) | 2003-06-30 |
CA2469195A1 (en) | 2003-06-26 |
WO2003051444A1 (en) | 2003-06-26 |
EP1455880A1 (en) | 2004-09-15 |
JP4276543B2 (en) | 2009-06-10 |
US20030114777A1 (en) | 2003-06-19 |
JP2005511258A (en) | 2005-04-28 |
US7670302B2 (en) | 2010-03-02 |
ATE457767T1 (en) | 2010-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7670302B2 (en) | Super elastic guidewire with shape retention tip | |
US6019736A (en) | Guidewire for catheter | |
US5238004A (en) | High elongation linear elastic guidewire | |
EP0526527B1 (en) | High elongation linear elastic guidewire | |
EP0868924B1 (en) | Superelastic guidewire with a shapeable tip | |
US6491648B1 (en) | Guidewire with tapered flexible core segment | |
JP2950995B2 (en) | Thin wall catheter with enhanced torque characteristics | |
US5916178A (en) | Steerable high support guidewire with thin wall nitinol tube | |
US6106485A (en) | Guidewire with shaped intermediate portion | |
EP0817656B1 (en) | High support nitinol tube guidewire with plastic plug transition | |
US7955272B2 (en) | High performance coil wire | |
US7993285B2 (en) | Medical device having flexible distal tip | |
WO1997032625A1 (en) | Intravascular guidewire | |
WO2002049704A2 (en) | Guidewire with tapered distal coil | |
JP2002505167A (en) | Flexible and kink-resistant low friction guidewire having a formable tip and method of manufacturing the same | |
JP2009523481A (en) | Titanium / molybdenum alloy guide wire | |
US20080114303A1 (en) | Guidewire | |
US6638267B1 (en) | Guidewire with hypotube and internal insert | |
EP1523366B1 (en) | Guidewire with tapered flexible core segment | |
JP4685218B2 (en) | Medical guidewire | |
WO2024044433A1 (en) | Medical devices with radiopaque coils | |
KR20080085160A (en) | Titanium molybdenum alloy guidewires |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |