US20100283450A1 - Particle detection - Google Patents
Particle detection Download PDFInfo
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- US20100283450A1 US20100283450A1 US11/984,511 US98451107A US2010283450A1 US 20100283450 A1 US20100283450 A1 US 20100283450A1 US 98451107 A US98451107 A US 98451107A US 2010283450 A1 US2010283450 A1 US 2010283450A1
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- Prior art keywords
- particle
- electrodes
- charge
- electrode
- characteristic
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects thereof, e.g. conductivity or capacity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means, e.g. by light scattering, diffraction, holography or imaging
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
Definitions
- This invention relates to particle detection and characterisation.
- apparatus for characterising particles including first means for determining the electrical charge on the particles and second means for determining a second characteristic of the particles, the apparatus being arranged to provide an indication of the nature of the particles according to the charge and the second characteristic.
- the second characteristic is preferably size and the means for determining size may be optical means.
- the apparatus may include a plurality of the first means for one of the second means.
- the first means may include means defining a pathway for the particles and a plurality of electrodes spaced along the pathway arranged to provide an electrical output as the particles pass along the pathway.
- the means defining the pathway preferably includes a tube. There are preferably five electrodes spaced along the pathway. The outermost electrodes may be grounded, the two electrodes adjacent the outermost electrodes may be connected together and a signal may be derived from the difference between the central electrode and the two interconnected electrodes.
- the tube may have an internal diameter of about 0.5 mm.
- the apparatus preferably includes means preventing particles greater than about 10 ⁇ m from entering the tube.
- a method of characterising particles including the steps of measuring the electrical charge on the particles, measuring a second characteristic of the particles and providing an output indicative of the nature of the particles from the charge and the second characteristic.
- the second characteristic is preferably size.
- apparatus for measuring the charge on a particle including a tube along which the particle is arranged to flow, first and second outer electrodes towards opposite ends of the tube, third and fourth electrodes adjacent the first and second electrodes respectively, a fifth electrode between the third and fourth electrodes, means connecting the first and second electrodes to ground, means connecting the third and fourth electrodes with one another and to measuring means, and means connecting the fifth electrode to the measuring means, the measuring means being arranged to subtract the signals on the third and fourth electrodes from the fifth electrode to derive a signal indicative of the charge on the particle.
- FIG. 1 is a perspective view of the apparatus
- FIG. 2 is a perspective view of the front side of the charge-measuring assembly
- FIG. 3 is a perspective view of the rear side of the charge-measuring assembly
- FIG. 4 is a perspective view of a single charge-measuring unit within the assembly of FIG. 3 ;
- FIG. 5 is a perspective view of a tube from the unit of FIG. 4 ;
- FIG. 6 is a graph showing the voltage output of the charge measuring unit.
- FIG. 7 is a diagram illustrating the electrical circuit of the apparatus.
- the apparatus includes a metal base board 1 on which is mounted a support assembly 2 of generally rectangular shape and having a longitudinally-extending recess 3 in which is received a charge-measuring assembly 4 with cooling fins on its upper surface.
- the support assembly 2 has a box-like inlet structure 5 on one side providing a plenum chamber for air drawn to the inlet side of the charge-measuring assembly.
- a box-like outlet structure 6 extending along the opposite side of the charge measuring assembly 4 includes a plenum chamber and an outlet opening on the lower surface of the board through which air can be pumped away from the apparatus.
- a third structure 7 provides electrical connection to the assembly 4 . Further details of the charge-measuring assembly 4 are given below.
- the board 1 also supports particle size measuring means in the form of an optical laser arrangement indicated generally by the numeral 10 .
- the arrangement includes a laser tube 11 mounted horizontally on the board 1 to extend parallel to the support assembly 2 .
- Two inclined mirror assemblies 12 and 13 are oriented to direct the beam of radiation emerging from one end of the tube 11 axially of the charge measuring assembly 4 and, in particular, the beam of radiation is incident on a window 14 in one end of the charge measuring assembly and passes along its length to emerge from its other end and be absorbed in an optical beam dump 15 .
- the charge measuring assembly 4 is shown in greater detail in FIGS. 2 and 3 . It comprises a rectangular metal block 20 with a forward surface 21 in which ten recesses 22 extend laterally of the block side-by-side towards its right-hand end.
- a photo multiplier tube (PMT) 23 is mounted on the forward surface towards the left-hand end of the block 20 for measuring the size of the particles.
- the rear surface 24 of the block as shown in FIG. 3 , has a shallow recess 25 extending along most of its length and has ten circular apertures 26 opening into the recess aligned with respective ones of the recesses 22 in the forward surface 21 .
- a groove 27 providing a laser pathway extends diametrically across the apertures 26 .
- the lower end of the groove 27 opens into the window 14 .
- the groove 27 opens into a tubular guide 28 extending to the end of the block 20 and terminated by a coupling 29 to which the optical beam dump 15 is connected.
- Each of the recesses 22 in the block 20 contains a charge sensor 40 of the kind shown in more detail in FIGS. 4 and 5 .
- Each sensor 40 includes a rectangular upper plate 41 and a smaller lower plate 42 separated from one another by two support pillars 43 and 44 .
- An O-ring seal 45 extends around the upper plate 41 to form an hermetic seal with a respective recess 22 , the sensor 40 being held in place by screws extending into tapped holes (not shown) in the block 20 through two screw holes 46 at opposite ends of the plate.
- the upper plate 41 has an air pipe 47 ( FIG. 4 ). On the underside of the plate 41 the pipe 47 supports and connects with the upper end of a charge sensor tube 50 , which is shown in more detail in FIG. 5 .
- the lower end of the charge sensor tube 50 is supported in a recess 70 in the lower plate 42 .
- the recess 70 is circular and tapers to a reduced diameter at its lower end to reduce stray capacitance between the metal structure and electrodes on the charge sensor tube 50 .
- the upper plate 41 also supports an electrical connector 49 connected to electrodes on the tube 50 .
- the tube 50 is shown in more detail in FIG. 5 and is of an electrically-insulative material such as glass or ceramic, it has a circular section with an outside diameter of about 1 mm, an inside diameter of about 0.5 mm and a length of about 30 mm.
- the tube 50 has five ring-shape electrodes on its outer surface spaced from one another along the length of the tube. The electrodes are on the outside of the tube because the air flowing through it may be humid and conductive.
- Two electrodes 51 and 52 at opposite ends of the tube 50 are each 8 mm long and are separated by insulating gaps 53 and 54 , each 0.5 mm long, from two intermediate electrodes 55 and 56 , which are each 0.5 mm long.
- a central electrode 57 which is 1 mm long, is separated from the intermediate electrodes by insulating gaps 58 and 59 , each 0.5 mm long.
- the two outer electrodes 51 and 52 are connected to ground.
- the two intermediate electrodes 55 and 56 are connected together and the signal on these is subtracted from the signal on the central electrode 57 using the circuit shown in FIG. 7 .
- the lower end of the tube 50 extends through the recess 70 and through a circular boss 60 formed on the lower surface of the lower plate 42 .
- the electrodes 51 , 52 , 55 , 56 57 are located towards the lower end of the tube 50 so that the distance between the charge measurement electrodes 55 , 56 and 57 and the particles' size measurement at the end of the tube is kept to a minimum.
- the circuit for each sensor 40 comprises two identical amplifying circuits 61 and 62 connected to the central electrode 57 and the intermediate electrode pair 55 and 56 respectively.
- Each amplifying circuit 61 and 62 includes a low-noise charge amplifier 63 , a low pass filter 64 , a second amplifier 65 and an analogue-to-digital converter 66 .
- the digital output from each circuit 61 and 62 is supplied to a subtracting unit 67 , which provides an output signal to a digital processor 68 with suitable processing to reduce noise.
- the processor 68 receives nine other inputs from the other nine sensor units 40 .
- the output signal from each sensor unit 40 takes the form shown in FIG. 6 .
- atmospheric air is drawn into and through the apparatus by a pump (not shown) located on the outlet side.
- the air is preconditioned with an elutriation filter of known kind to remove particles outside the range 1 ⁇ m to 10 ⁇ m. Particles that are too small would give rise to noise; particles that are too large would risk clogging the tubes 50 . It is important that the technique used to remove particles outside the desired size range has only a minimal effect on the charge of the remaining particles.
- the preconditioned air containing suspect particles flows to the charge sensing tubes 50 in each of the ten sensors 40 .
- the flow rate through each tube 50 is about 100 m/sec.
- the width of the pulse P produced is highly constrained.
- the width of the pulse P depends on the diameter of the electrode rings 51 , 52 , 55 , 56 and 57 with larger diameters producing a more spread out signal. Short duration pulses are important if the apparatus is to be able to provide reliable identification when there is a high throughput of particles.
- the magnitude of the pulse P depends on the charge on the particle.
- the output from the sensors 40 is supplied to the processor 68 , which adds a timestamp to the data and is then stored to hard disc.
- the laser size measuring arrangement 10 continuously transmits a beam of laser radiation from the laser tube 11 , which is directed along the groove 27 in the block 20 where it intersects particles emerging from the lower end of the tubes 50 .
- the output of the PMT 23 is dependent on the size of the particle and this output is also supplied to the processor 68 .
- the processor 68 therefore, receives information about the charge and size of each particle detected. This is compared with stored information to provide an output indicative of the nature of the particles.
- particles in particular biological particles, carrying a relatively high electrical charge are more likely to have been generated artificially, and therefore present a possible hazard, because the usual mechanisms for producing small particles, such as aerosol nozzles and the like involve impact at high velocity. This causes disruption of the molecules, typically resulting in a charge on the particles.
- the dimensions of the tube can be varied but its diameter should be as small as possible compatible with producing flow through it sufficient to avoid clogging. It is believed that the minimum practical internal diameter is about 500 ⁇ m, with a wall thickness of about 250 ⁇ m.
- the number of charge sensors can be varied in order to achieve the desired throughput.
- One possible problem with the charge sensor tubes is that the particles may interact with the inside of the tubes to produce tribocharging. Glass and ceramic are known to have a fairly high propensity to tribocharging, although this is dependent on the nature of the particles.
- One possible alternative material is Mylar (a Registered Trade Mark of E. I. Du Pont de Nemours and Company), which is a polyester film material close to neutral in the triboelectric series, although this is only presently available in film form.
Abstract
Particle detection and characterising apparatus has an insulating tube (50) along which the particles flow. Five electrodes (51, 52, 55, 56) and (57) spaced along the outside of the tube are connected via amplifiers (61) and (62) to a processor (68) arranged to measure the charge on the particles. The apparatus also includes a laser (11) and photomultiplier tube (23) arranged to measure the size of the particles so that the nature of the particles can be characterised from their electrical charge and size.
Description
- This invention relates to particle detection and characterisation.
- Various techniques are used to detect and identify small airborne particles, such as ion mobility spectrometry, cyclone collection or the like. These suffer form various disadvantages especially when detecting small particles, such as biological particles.
- It is an object of the present invention to provide an alternative apparatus and method of characterising particles.
- According to one aspect of the present invention there is provided apparatus for characterising particles including first means for determining the electrical charge on the particles and second means for determining a second characteristic of the particles, the apparatus being arranged to provide an indication of the nature of the particles according to the charge and the second characteristic.
- The second characteristic is preferably size and the means for determining size may be optical means. The apparatus may include a plurality of the first means for one of the second means. The first means may include means defining a pathway for the particles and a plurality of electrodes spaced along the pathway arranged to provide an electrical output as the particles pass along the pathway. The means defining the pathway preferably includes a tube. There are preferably five electrodes spaced along the pathway. The outermost electrodes may be grounded, the two electrodes adjacent the outermost electrodes may be connected together and a signal may be derived from the difference between the central electrode and the two interconnected electrodes. The tube may have an internal diameter of about 0.5 mm. The apparatus preferably includes means preventing particles greater than about 10 μm from entering the tube.
- According to another aspect of the present invention there is provided a method of characterising particles including the steps of measuring the electrical charge on the particles, measuring a second characteristic of the particles and providing an output indicative of the nature of the particles from the charge and the second characteristic.
- The second characteristic is preferably size.
- According to a third aspect of the present invention there is provided apparatus for measuring the charge on a particle including a tube along which the particle is arranged to flow, first and second outer electrodes towards opposite ends of the tube, third and fourth electrodes adjacent the first and second electrodes respectively, a fifth electrode between the third and fourth electrodes, means connecting the first and second electrodes to ground, means connecting the third and fourth electrodes with one another and to measuring means, and means connecting the fifth electrode to the measuring means, the measuring means being arranged to subtract the signals on the third and fourth electrodes from the fifth electrode to derive a signal indicative of the charge on the particle.
- Particle characterisation apparatus according to the present invention, will now be described, by way of example, with reference to the accompanying drawings, in which:
-
FIG. 1 is a perspective view of the apparatus; -
FIG. 2 is a perspective view of the front side of the charge-measuring assembly; -
FIG. 3 is a perspective view of the rear side of the charge-measuring assembly; -
FIG. 4 is a perspective view of a single charge-measuring unit within the assembly ofFIG. 3 ; -
FIG. 5 is a perspective view of a tube from the unit ofFIG. 4 ; -
FIG. 6 is a graph showing the voltage output of the charge measuring unit; and -
FIG. 7 is a diagram illustrating the electrical circuit of the apparatus. - With reference first to
FIG. 1 , the apparatus includes ametal base board 1 on which is mounted asupport assembly 2 of generally rectangular shape and having a longitudinally-extendingrecess 3 in which is received a charge-measuring assembly 4 with cooling fins on its upper surface. Thesupport assembly 2 has a box-like inlet structure 5 on one side providing a plenum chamber for air drawn to the inlet side of the charge-measuring assembly. A box-like outlet structure 6 extending along the opposite side of thecharge measuring assembly 4 includes a plenum chamber and an outlet opening on the lower surface of the board through which air can be pumped away from the apparatus. Athird structure 7 provides electrical connection to theassembly 4. Further details of the charge-measuring assembly 4 are given below. - The
board 1 also supports particle size measuring means in the form of an optical laser arrangement indicated generally by thenumeral 10. The arrangement includes alaser tube 11 mounted horizontally on theboard 1 to extend parallel to thesupport assembly 2. Twoinclined mirror assemblies tube 11 axially of thecharge measuring assembly 4 and, in particular, the beam of radiation is incident on awindow 14 in one end of the charge measuring assembly and passes along its length to emerge from its other end and be absorbed in anoptical beam dump 15. - The
charge measuring assembly 4 is shown in greater detail inFIGS. 2 and 3 . It comprises arectangular metal block 20 with aforward surface 21 in which tenrecesses 22 extend laterally of the block side-by-side towards its right-hand end. A photo multiplier tube (PMT) 23 is mounted on the forward surface towards the left-hand end of theblock 20 for measuring the size of the particles. Therear surface 24 of the block, as shown inFIG. 3 , has ashallow recess 25 extending along most of its length and has tencircular apertures 26 opening into the recess aligned with respective ones of therecesses 22 in theforward surface 21. Agroove 27 providing a laser pathway extends diametrically across theapertures 26. The lower end of thegroove 27, as represented inFIG. 3 , opens into thewindow 14. At its other end, thegroove 27 opens into atubular guide 28 extending to the end of theblock 20 and terminated by acoupling 29 to which theoptical beam dump 15 is connected. - Each of the
recesses 22 in theblock 20 contains acharge sensor 40 of the kind shown in more detail inFIGS. 4 and 5 . Eachsensor 40 includes a rectangularupper plate 41 and a smallerlower plate 42 separated from one another by twosupport pillars ring seal 45 extends around theupper plate 41 to form an hermetic seal with arespective recess 22, thesensor 40 being held in place by screws extending into tapped holes (not shown) in theblock 20 through twoscrew holes 46 at opposite ends of the plate. Theupper plate 41 has an air pipe 47 (FIG. 4 ). On the underside of theplate 41 thepipe 47 supports and connects with the upper end of acharge sensor tube 50, which is shown in more detail inFIG. 5 . The lower end of thecharge sensor tube 50 is supported in arecess 70 in thelower plate 42. Therecess 70 is circular and tapers to a reduced diameter at its lower end to reduce stray capacitance between the metal structure and electrodes on thecharge sensor tube 50. Theupper plate 41 also supports anelectrical connector 49 connected to electrodes on thetube 50. - The
tube 50 is shown in more detail inFIG. 5 and is of an electrically-insulative material such as glass or ceramic, it has a circular section with an outside diameter of about 1 mm, an inside diameter of about 0.5 mm and a length of about 30 mm. Thetube 50 has five ring-shape electrodes on its outer surface spaced from one another along the length of the tube. The electrodes are on the outside of the tube because the air flowing through it may be humid and conductive. Twoelectrodes tube 50 are each 8 mm long and are separated byinsulating gaps intermediate electrodes central electrode 57, which is 1 mm long, is separated from the intermediate electrodes byinsulating gaps outer electrodes intermediate electrodes central electrode 57 using the circuit shown inFIG. 7 . The lower end of thetube 50 extends through therecess 70 and through acircular boss 60 formed on the lower surface of thelower plate 42. Theelectrodes tube 50 so that the distance between thecharge measurement electrodes - The circuit for each
sensor 40 comprises two identical amplifyingcircuits central electrode 57 and theintermediate electrode pair circuit noise charge amplifier 63, alow pass filter 64, asecond amplifier 65 and an analogue-to-digital converter 66. The digital output from eachcircuit subtracting unit 67, which provides an output signal to adigital processor 68 with suitable processing to reduce noise. Theprocessor 68 receives nine other inputs from the other ninesensor units 40. The output signal from eachsensor unit 40 takes the form shown inFIG. 6 . - In operation, atmospheric air is drawn into and through the apparatus by a pump (not shown) located on the outlet side. The air is preconditioned with an elutriation filter of known kind to remove particles outside the
range 1 μm to 10 μm. Particles that are too small would give rise to noise; particles that are too large would risk clogging thetubes 50. It is important that the technique used to remove particles outside the desired size range has only a minimal effect on the charge of the remaining particles. - The preconditioned air containing suspect particles flows to the
charge sensing tubes 50 in each of the tensensors 40. With a flow rate of about 10 L/min through the apparatus, the flow rate through eachtube 50 is about 100 m/sec. When a particle is present in the air flowing through asensor 40 an output response of the kind shown inFIG. 6 is produced. It can be seen that the width of the pulse P produced is highly constrained. The width of the pulse P depends on the diameter of the electrode rings 51, 52, 55, 56 and 57 with larger diameters producing a more spread out signal. Short duration pulses are important if the apparatus is to be able to provide reliable identification when there is a high throughput of particles. The magnitude of the pulse P depends on the charge on the particle. The output from thesensors 40 is supplied to theprocessor 68, which adds a timestamp to the data and is then stored to hard disc. The lasersize measuring arrangement 10 continuously transmits a beam of laser radiation from thelaser tube 11, which is directed along thegroove 27 in theblock 20 where it intersects particles emerging from the lower end of thetubes 50. The output of thePMT 23 is dependent on the size of the particle and this output is also supplied to theprocessor 68. Theprocessor 68, therefore, receives information about the charge and size of each particle detected. This is compared with stored information to provide an output indicative of the nature of the particles. - It is believed that particles, in particular biological particles, carrying a relatively high electrical charge are more likely to have been generated artificially, and therefore present a possible hazard, because the usual mechanisms for producing small particles, such as aerosol nozzles and the like involve impact at high velocity. This causes disruption of the molecules, typically resulting in a charge on the particles.
- The dimensions of the tube can be varied but its diameter should be as small as possible compatible with producing flow through it sufficient to avoid clogging. It is believed that the minimum practical internal diameter is about 500 μm, with a wall thickness of about 250 μm. The number of charge sensors can be varied in order to achieve the desired throughput.
- One possible problem with the charge sensor tubes is that the particles may interact with the inside of the tubes to produce tribocharging. Glass and ceramic are known to have a fairly high propensity to tribocharging, although this is dependent on the nature of the particles. One possible alternative material is Mylar (a Registered Trade Mark of E. I. Du Pont de Nemours and Company), which is a polyester film material close to neutral in the triboelectric series, although this is only presently available in film form.
- Instead of using an optical size measuring technique to identify a second characteristic of the particles it may be possible to identify the nature of particles from their charge and some other characteristic.
Claims (16)
1. An apparatus for characterizing a particle comprising:
(a) an electrical charge sensor adapted to determine an electrical charge on the particle; and
(b) an optical device adapted to determine a second characteristic of the particle,
wherein the apparatus is adapted to provide an indication of the nature of the particle according to the charge and the second characteristic.
2. The apparatus according to claim 1 , wherein the second characteristic is size.
3. The apparatus according to claim 1 , wherein the electrical charge sensor comprises a pathway for the particle and a plurality of electrodes spaced along the pathway arranged to provide an electrical output as the particle passes along the pathway.
4. The apparatus according to claim 3 , wherein the pathway is provided by an electrically insulative tube, and wherein the plurality of electrodes are provided on an external surface of the tube.
5. The apparatus according to claim 3 , wherein there are five electrodes spaced along the pathway.
6. The apparatus according to claim 3 , wherein the outermost electrodes are grounded, wherein two electrodes adjacent to outermost two electrodes are interconnected, and wherein a signal is derived from the difference between the central electrode and the two interconnected electrodes.
7. The apparatus according to claim 4 , wherein the tube has an internal diameter of substantially 0.5 mm.
8. The apparatus according to claim 4 , further comprising a filter adapted to prevent particles greater than substantially 10 μm from entering the tube.
9. A method of characterizing a particle comprising:
(a) measuring charge on the particle;
(b) measuring an optical characteristic of the particle; and
(c) providing an output indicative of the nature of the particle from the combination of both the charge and the optical characteristic.
10. A method according to claim 9 , wherein the optical characteristic is indicative of the size of the particle.
11. An apparatus for measuring a charge on a particle comprising:
(a) a tube comprising a first end and a second end along which the particle is arranged to flow,
(b) a first and a second outer electrode, wherein the first outer electrode is located adjacent to the first end and the second outer electrode is located adjacent to the second end,
(b) a third electrode adjacent to the first outer electrode and a fourth electrode adjacent to the second outer electrode,
(c) a fifth electrode located between the third and fourth electrodes,
(d) a connection connecting the first and second outer electrodes to ground,
(e) a connection connecting the third electrode to the fourth electrode and connecting the connected third and the fourth electrodes to a measuring circuit, and
(f) a connection connecting the fifth electrode to the measuring circuit, wherein the measuring circuit is adapted to subtract the signals on the third and fourth electrodes from the signal on the fifth electrode to derive a signal indicative of the charge on the particle.
12. An apparatus for characterizing a particle comprising an electrical charge sensor adapted to determine an electrical charge on the particle, wherein the electrical charge sensor comprises a pathway having at least three electrodes spaced along the length of the pathway comprising a central electrode and two outer electrodes, wherein the two outer electrodes are connected together, wherein a charge signal is derived from the difference between a charge on the central electrode and a charge on the connected two outer electrodes, and wherein the apparatus is adapted to derive an indication of the nature of the particles from the charge signal.
13. The apparatus according to claim 12 , further comprising a second device adapted to determine a second characteristic of the particle, wherein the apparatus is adapted to characterize a particle using the combination of both the charge signal and the second characteristic.
14. The apparatus according to claim 13 , wherein the second characteristic is size.
15. The apparatus according to claim 13 , wherein the second device is an optical device.
16. An apparatus for characterizing a particle in a tube comprising
(a) a plurality of electrodes space along the tube and adapted to determine an electrical charge on the particle, and
(b) a second device adapted to determine a second characteristic of the particle unrelated to the electrical charge,
wherein the apparatus is adapted to provide an indication of the nature of the particle using a combination of both the charge and the second characteristic.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US11/984,511 US20100283450A1 (en) | 2003-09-05 | 2007-11-19 | Particle detection |
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GB0320809.7 | 2003-09-05 | ||
GBGB0320809.7A GB0320809D0 (en) | 2003-09-05 | 2003-09-05 | Particle detection |
US10/595,082 US7298127B2 (en) | 2003-09-05 | 2004-09-03 | Particle detection |
PCT/GB2004/003755 WO2005024393A1 (en) | 2003-09-05 | 2004-09-03 | Particle detection |
US11/984,511 US20100283450A1 (en) | 2003-09-05 | 2007-11-19 | Particle detection |
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PCT/GB2004/003755 Continuation WO2005024393A1 (en) | 2003-09-05 | 2004-09-03 | Particle detection |
US11/595,082 Continuation US7638872B2 (en) | 2005-11-09 | 2006-11-09 | Power semiconductor module |
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US20100283450A1 true US20100283450A1 (en) | 2010-11-11 |
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EP (1) | EP1660862A1 (en) |
JP (1) | JP2007504454A (en) |
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CN104089860A (en) * | 2014-06-03 | 2014-10-08 | 中绿环保科技股份有限公司 | On-line continuous particle-concentration monitor |
US20160041078A1 (en) * | 2014-08-11 | 2016-02-11 | Lg Electronics Inc. | Apparatus for detecting particles |
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GB0320809D0 (en) * | 2003-09-05 | 2003-10-08 | Smiths Group Plc | Particle detection |
DE102007033215A1 (en) * | 2007-07-17 | 2009-01-22 | Robert Bosch Gmbh | Sensor, method and their use for detecting the size distribution of particles in a gas stream |
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CN116106522B (en) * | 2023-04-11 | 2023-09-08 | 深圳市帝迈生物技术有限公司 | Blood analysis device |
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- 2003-09-05 GB GBGB0320809.7A patent/GB0320809D0/en not_active Ceased
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- 2004-09-03 CA CA002534844A patent/CA2534844A1/en not_active Abandoned
- 2004-09-03 EP EP04768302A patent/EP1660862A1/en not_active Withdrawn
- 2004-09-03 WO PCT/GB2004/003755 patent/WO2005024393A1/en active Application Filing
- 2004-09-03 US US10/595,082 patent/US7298127B2/en not_active Expired - Fee Related
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US3852768A (en) * | 1973-08-17 | 1974-12-03 | Ibm | Charge detection for ink jet printers |
US4117715A (en) * | 1977-07-05 | 1978-10-03 | Ransburg Corporation | Apparatus for measuring charge on, and density of, airborne particulates |
US5214386A (en) * | 1989-03-08 | 1993-05-25 | Hermann Singer | Apparatus and method for measuring particles in polydispersed systems and particle concentrations of monodispersed aerosols |
US6553849B1 (en) * | 1998-10-28 | 2003-04-29 | Dillon F. Scofield | Electrodynamic particle size analyzer |
US6862536B2 (en) * | 2000-07-19 | 2005-03-01 | Tr-Tech Int. Oy | Measuring system and a method for measuring particle velocity and/or particle velocity distribution and/or particle size distribution |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104089860A (en) * | 2014-06-03 | 2014-10-08 | 中绿环保科技股份有限公司 | On-line continuous particle-concentration monitor |
US20160041078A1 (en) * | 2014-08-11 | 2016-02-11 | Lg Electronics Inc. | Apparatus for detecting particles |
Also Published As
Publication number | Publication date |
---|---|
US20060164094A1 (en) | 2006-07-27 |
GB0320809D0 (en) | 2003-10-08 |
WO2005024393A1 (en) | 2005-03-17 |
CA2534844A1 (en) | 2005-03-17 |
US7298127B2 (en) | 2007-11-20 |
EP1660862A1 (en) | 2006-05-31 |
JP2007504454A (en) | 2007-03-01 |
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