US20130001121A1 - Backup kit for a patient-specific arthroplasty kit assembly - Google Patents
Backup kit for a patient-specific arthroplasty kit assembly Download PDFInfo
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- US20130001121A1 US20130001121A1 US13/174,856 US201113174856A US2013001121A1 US 20130001121 A1 US20130001121 A1 US 20130001121A1 US 201113174856 A US201113174856 A US 201113174856A US 2013001121 A1 US2013001121 A1 US 2013001121A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/14—Surgical saws ; Accessories therefor
- A61B17/15—Guides therefor
- A61B17/154—Guides therefor for preparing bone for knee prosthesis
- A61B17/155—Cutting femur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/14—Surgical saws ; Accessories therefor
- A61B17/15—Guides therefor
- A61B17/154—Guides therefor for preparing bone for knee prosthesis
- A61B17/157—Cutting tibia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/17—Guides or aligning means for drills, mills, pins or wires
- A61B17/1739—Guides or aligning means for drills, mills, pins or wires specially adapted for particular parts of the body
- A61B17/1764—Guides or aligning means for drills, mills, pins or wires specially adapted for particular parts of the body for the knee
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B2017/568—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor produced with shape and dimensions specific for an individual patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
- A61B2034/108—Computer aided selection or customisation of medical implants or cutting guides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0095—Packages or dispensers for prostheses or other implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
Definitions
- the present teachings provide a backup kit including backup arthroplasty implants for a shipment of a plurality of patient-specific arthroplasty kits for a plurality of corresponding arthroplasty procedures at the same medical facility.
- the patient-specific arthroplasty kits generally include patient-specific alignment guides, custom and non-custom implants and other instruments for use during an arthroplasty procedure.
- the patient-specific alignment guides (and patient-specific implants, when used) are designed and constructed preoperatively based on three-dimensional digital images of the patient's joint that is scheduled to undergo arthroplasty.
- the digital images of the patient's joint can be reconstructed from medical scans of the patient using commercially available CAD (Computer Aided Design) and/or other imaging software.
- CAD Computer Aided Design
- the present teachings provide a method for preparing a backup kit for a shipment of patient-specific arthroplasty kits for corresponding arthroplasty procedures scheduled at the same medical facility.
- the method includes providing a database with data from completed arthroplasty procedures that were performed using patient-specific arthroplasty kits.
- the database includes comparisons between preoperatively planned implant size and intraoperatively implanted (actual) implant size.
- a statistically expected implant size deviation from a planned implant size for each implant included in the shipment is determined using the database.
- a backup kit of backup implants is assembled for the shipment. The number and size of the backup implants is determined from the statistically expected implant size deviations.
- the present teachings also provide a backup kit for a plurality of patient-specific arthroplasty procedures scheduled at the same medical facility.
- the backup kit includes a plurality of backup implants selected for a shipment of a plurality of patient-specific arthroplasty kits for the medical facility.
- Each patient-specific arthroplasty kit is configured for corresponding arthroplasty procedures at the same medical facility.
- the number and size of the backup implants is determined from statistically expected implant size deviations from planned implant sizes in the corresponding arthroplasty kits using a compliance database.
- the compliance database includes data from completed arthroplasty procedures performed using patient-specific arthroplasty kits.
- the compliance database includes comparisons between preoperatively planned implant sizes and intraoperatively implanted implant sizes.
- FIG. 1 is a schematic view of an exemplary patient-specific arthroplasty kit
- FIG. 2 is a schematic view of a shipment of a plurality of patient-specific arthroplasty kits similar to the patient-specific arthroplasty kit of FIG. 1 according to the present teachings;
- FIG. 3 is a schematic view of a backup kit for the shipment of FIG. 2 according to the present teachings
- FIG. 4 is a flowchart for a method according to the present teachings.
- FIG. 5 is an exemplary partial listing of a compliance database according to the present teachings.
- the present teachings provide a backup kit that includes backup arthroplasty implants for a shipment of a plurality of patient-specific arthroplasty kits for use at the same medical facility for a plurality of corresponding arthroplasty procedures.
- the patient-specific arthroplasty kits generally include patient-specific guides, custom and non-custom implants and other instruments for use during an arthroplasty procedure such as, for example, cutting guides, drill guides, cutting blocks, fixation pins, etc.
- the patient-specific guides and/or patient-specific implants, if used, are designed and constructed preoperatively based on three-dimensional digital images of the patient's joint that is scheduled to undergo arthroplasty.
- the backup kit includes backup implants of various sizes to be included with each particular shipment. The number and sizes of the backup implants in the backup kit are determined from a statistical analysis of patient-outcomes that are stored in a compliance database, as discussed below.
- patient-specific devices including implants and/or patient-specific alignment guides, resection guides or other instruments can be designed preoperatively using computer-assisted imaging methods.
- Three-dimensional digital images of the patient's joint anatomy can be reconstructed from MRI, CT, ultrasound, X-ray, or other medical scans of the patient's anatomy.
- Various CAD programs and/or other software can be utilized for three-dimensional digital image reconstruction, such as, for example, software commercially available from Materialise USA, Madison, Mich.
- Imaging data of the relevant joint anatomy of a patient can be obtained at a medical facility or doctor's office using any of the medical imaging methods described above.
- the imaging data can include, for example, various medical scans of a relevant joint portion or other relevant portion of the patient's anatomy, as needed for joint or other anatomy modeling and, optionally, for determination of an implant alignment axis or for other alignment purposes.
- the imaging data thus obtained and other associated information can be used to construct a three-dimensional computer (digital) image of the joint or other portion of the anatomy of the patient, such as, the hip joint, knee joint, etc.
- the three-dimensional digital image of the patient's anatomy is also used to formulate a preoperative surgical plan for the patient including, for example, location and orientation of resections, removal of osteophytes or other protrusions, mechanical alignment, deformity correction, ligament balancing, or other preoperative planned procedures
- the preoperative surgical plan can also include the design and construction of patient-specific alignment guides, resection guides or other patient-specific instruments, and, optionally, the design and construction of patient-specific implants.
- the preoperative surgical plan can include the determination and selection of particular sizes of non-custom implants, digital images of which can be viewed and compared relative to the three-dimensional digital image of the patient's anatomy on a digital display.
- the patient-specific devices are configured to match at least a portion of a joint anatomy of a specific patient and are generally designed and configured using computer modeling based on the patient's reconstructed three-dimensional digital image of the patient's corresponding joint anatomy.
- Each patient-specific device includes a three-dimensional patient-specific surface that is configured to conformingly contact and match a corresponding surface of the patient (with or without cartilage or other soft tissue), using the reconstructed three-dimensional digital image of the patient's anatomy and the computer methods discussed above.
- a patient-specific device can register and nestingly mate with the corresponding bone surface (with or without articular cartilage) of the specific patient in only one position.
- the three-dimensional digital model of the patient's anatomy can be viewed on a computer display or other electronic screen and can also be reproduced as a hard copy on film or other medium and viewed by direct or indirect or backlight illumination.
- the digital model can be sized for viewing on any appropriate screen size (including handheld mobile devices, such as smart phones, PDAs or tablets) and may be cropped, rotated, etc., as selected by the individual (e.g., the surgeon) viewing the screen.
- the surgeon's review of the surgical plan may include implant selection, and/or a request for one or more patient-specific instruments, such as alignment guides, resection guides or other instruments to be used with the selected implant.
- patient-specific devices can be manufactured by rapid prototyping methods, such as stereolithography or other similar methods or by CNC milling, or other automated or computer-controlled machining or robotic methods.
- the patient-specific instruments, the selected implants and optionally other disposable instruments can be sterilized, assembled in a patient-specific kit and forwarded to the surgeon or the surgeon's medical facility for implantation.
- the selected implants can be non-custom implants of a size determined and approved by the surgeon in the preoperative plan for the patient.
- an omnibus patient-specific kit assembly 200 can include a plurality of patient-specific arthroplasty kits 100 ( 100 A, 1008 , 100 C, etc.) for shipment to a single medical facility.
- Each patient-specific arthroplasty kit 100 A, 100 B, 100 C can be labeled with the patient's name or identification number (ID), such as A, B, C, the corresponding surgeon's name, X, Y, Z and the side of the joint for the procedure, R or L for right or left, for example, or other information.
- ID identification number
- each patient-specific component in each patient-specific arthroplasty kit can also be labeled with the patient's name, the joint side, etc.
- the present teachings provide a method to design and prepare a backup kit 300 (see FIG. 3 ) for an entire bulk order or shipment that includes several patient-specific arthroplasty kits, as discussed below. Accordingly, the present teachings reduce weight, expense and unnecessary backup implant components for each patient-specific kit while providing the surgeon(s) and or the facility with sufficient oversize or undersize implants for the totality of the procedures, rather than for each single procedure.
- the determination of the number and size of additional or backup implants to be included in the backup kit 300 is made using statistical analysis of the size outcomes previous procedures which are stored in a compliance database, as described below. Duplicate size backup implants can also be included.
- the patient-specific arthroplasty kit 100 can include, for example, a patient-specific femoral alignment guide 110 , a patient-specific tibial alignment guide 118 , a femoral drill guide 112 , a tibial drill guide 120 , a femoral distal cutting block 114 , a tibial cutting block 130 , a four-in-one femoral cutting block 116 , and a tibial template 122 .
- the patient-specific alignment guides 110 , 118 are single-use guides and disposable.
- the various drill guides and cutting blocks can be re-sterilizable and reusable, although disposable drill guides, cutting blocks and other tools can also be designed. Additionally, a set of trochar pins 132 and a set of spring drill pins 134 can be included. Depending on the surgeon's preferences, additional tools and/or medical products and supplies can be included, such as cutting blades, bone cement, biologics, etc.
- the patient-specific arthroplasty kit 100 can include a set of arthroplasty implants, such as, for example, a femoral implant 150 , a bearing 152 and a tibial implant 154 , for an exemplary total knee arthroplasty procedure, or other implant components depending on the surgical procedure and the surgeon's preference.
- the arthroplasty implants can be either patient-specific or non-custom implants.
- Semi-custom arthroplasty implants i.e., implants including some patient-specific features and some standard, non-custom features can also be used, as described, for example, in commonly assigned U.S. patent application Ser. No. 12/872,663, filed Aug. 31, 2010, referenced above (and incorporated by reference herein).
- the implants or implant components 150 , 152 , 154 included in each patient-specific arthroplasty kit 100 can be non-custom components of a size selected during the preoperative plan for the patient. Predominantly, the selected or planned implant size is found to be a match and no change in implant size is required intraoperatively. For the few cases that the implant-size is found intraoperatively, for various reasons, not to be the best match, a best match implant can be found in the preoperatively prepared backup kit 300 with a degree of a built-in or preoperatively determined degree probability, using a compliance database 500 , as discussed below.
- the backup kit 300 can include a predetermined number of backup implant components.
- each implant component 150 , 152 , 154 is shown in the single backup kit 300 that accompanies the patient-specific kit assembly 200 .
- the selection of number and sizes the implant components to be included in the backup kit is discussed below with reference to FIGS. 4 and 5 .
- the compliance database 500 can be generated from information collected for each arthroplasty procedure for which a patient-specific arthroplasty kit was provided.
- the compliance database 500 can include the planned implant size, as well as the actual implant size that was eventually used.
- Information collected and provided by the database 500 can also include date of the procedure, patient Identification, surgeon name, the side (R right, L left) for the procedure and other characteristics of the patient, such as, for example, weight, ethnicity or race, gender, age or other characteristics that may be of significance in selecting implant size or that can be factors for a size deviation or mismatch.
- the implant sizes presented are for a femoral component 150 of the Vanguard® Knee Complete System, commercially available from Biomet Manufacturing Corp., Warsaw, Indiana.
- the available sizes correspond to mediolateral (ML) dimensions of the femur in mm.
- the interval between sizes for the Vanguard® Knee, for example, is 2.5 mm for sizes ranging from size 55 to size 75.
- a size 80 mm is also available.
- nine sizes are available for the tibial component 154 and seven sizes for the bearing 152 for the Vanguard® Knee.
- Implanting the wrong size, i.e., implant mis-sizing for the femoral implant 150 can result in excessive mediolateral overhang, especially in women, and can cause over-tightening of the knee capsule when a larger size is used.
- Providing backup sizes (one size larger or one size smaller than a planned size) for each and every implant in the shipment to the same facility can be costly, wasteful and inefficient both in bulk and weight.
- the compliance database 500 can be created and used to reduce the number of backup implants for the shipment, while still providing a high probability that the intraoperatively determined implant size is the planned size or is included in the backup kit.
- the partial data presented chronologically in FIG. 5 may be somewhat misleading in that they show a higher proportion of mismatches between planned and actual implant sizes than is the case when all the available data is considered for a longer period of time.
- the compliance database 500 is updated frequently or for each procedure performed, and that the contents of the backup kit 300 can then be determined by statistical analysis of the updated compliance database 500 . For example, if N patient-specific arthroplasty kits 100 are required for a single day D in a medical facility M, and each patient-specific arthroplasty kit 100 includes one implant of the type 150 (femoral knee component), then the database is analyzed to determine the proportion of higher and lower sizes that may be needed for a set of N implants of type 150 and having a particular size.
- the statistical analysis in its simplest form, may be based on percentages, or may include other considerations, such as reduction of mismatches over time as the technology evolves, patient characteristics, surgeon preferences, various weighing factors and other parameters.
- the statistical analysis can also include a specified contingency or probability coverage, i.e., what percentage of all mismatch cases should be covered, such as, for example from 98% or higher. Error analysis, standard deviation analysis, data reliability analysis and other statistical methods and algorithms known in the art can also be considered in the calculations.
- the compliance database 500 can depend on the characteristics of the implants and instruments used and can, therefore, vary from manufacturer to manufacturer. Accordingly, a relevant compliance database 500 can be generated or otherwise available to be accessed for determining the backup kit for a particular manufacturer according to the present teachings.
- the surgical schedule for the date Dec. 8, 2008 includes two R (right side) components of size 70 and three R components of size 67.5.
- two backup implant of size R67.5 for planned implant size R70 and one backup implant of size R65 for planned size R67.5 may be provided in the backup kit 300 .
- Duplicative backup implants backup implant has same size as planned implant size
- the number of duplicative backup implants can be determined from statistical analysis of data included in the compliance database 500 , or from other historical records or databases, or from surgeon and/or medical facility preferences and requirements.
- the backup kit 300 may be prepared for all the arthroplasty procedures performed at the same medical facility M for a different period of time, a week, for example. For the week of Dec. 1, 2008 to Dec. 5, 2008, for example, five L67.5 implants were planned. One backup implant of size L65 can be included in the backup kit based on the 11% rate of oversize mismatch. If the undersize mismatch rate is only 2.8%, as in data presented above, a separate backup kit 300 that includes bigger sizes for the lower chance of undersize planned implants may be maintained at facility M to be accessed as needed and replenished periodically. A backup kit with larger sizes for undersize planned implants can be prepared, for example, using estimates based on anticipated needs for longer periods of time, such as, per month, quarterly, etc.
- the rate of mismatch can be calculated from the database for each particular size. For example, if the rate of oversize mismatch is x % for a particular implant size N, then for every hundred implants of size N (in mm) in one shipment (a patient-specific kit assembly 200 ) of patient-specific arthroplasty kits 100 , an x number of implants of one size lower than N, i.e., N-2.5, can be included in the backup kit 300 . If only ten implants are included in the backup kit 300 , then x/10 implants of the smaller size are included in the backup kit 300 .
- the statistically determined number of backup implants for each planned implant size in the shipment (or patient-specific kit assembly) 200 of patient-specific arthroplasty kits 100 is not necessarily an integer and can be rounded up or down to the nearest integer number.
- backup implants can be included in the backup kit 300 , above and beyond those that can be statistically required.
- a surgeon may require a larger size backup implant for any planned size below 60 mm.
- Such considerations can be used to modify the backup kit 300 after the backup implant components have been determined by statistical analysis. In some cases, the contents determined by statistical analysis may already satisfy the surgeon's or the medical facility's additional requirements.
- a flowchart of a method of assembling a backup kit 300 is illustrated.
- a compliance database 500 is created or otherwise provided for access.
- an omnibus patient-specific kit assembly or shipment 200 is prepared for a facility M.
- the patient-specific kit assembly 200 includes a plurality of patient-specific arthroplasty kits 100 that are scheduled to be performed on the same day or within a specified number of days, such as, for example, on the same forthcoming week.
- the sizes of the various implants of the patient-specific kit assembly 200 and corresponding patient-characteristic can be identified at block 404 .
- a statistical analysis can be performed at block 406 to determine the likelihood of deviation or mismatch between preoperatively planned implant sizes and actual implant sizes as predicted by the compliance database 500 . Based on the results of the statistical analysis, expected deviations in implant size, i.e., the number of planned implants expected to be oversized or undersized can be determined at block 408 and a backup kit of implants can then be assembled at block 410 .
- the compliance database 500 can be updated at 412 with data from the new arthroplasty procedures that have been performed.
- a compliance database 500 of preoperatively planned and actual (intraoperatively selected) implants can be created from data collected from patient-specific preoperative plans and actual arthroplasty usage.
- the database provides details of mismatches or deviations between a planned implant size and an actually used implant size.
- the information in the database can be statistically analyzed to help determine the number and sizes of extra of backup implants to be included in a backup kit 300 for a plurality of arthroplasty procedures that are planned preoperatively and include patient-specific arthroplasty kits 100 .
- Example embodiments are provided so that this disclosure is thorough, and fully conveys the scope to those who are skilled in the art. Numerous specific details are set forth, such as examples of specific components, devices, and methods, to provide a thorough understanding of embodiments of the present disclosure.
Abstract
A method for preparing a backup kit for a plurality of patient-specific arthroplasty procedures scheduled at the same medical facility includes providing a database with data from completed arthroplasty procedures using patient-specific arthroplasty kits. The database includes comparisons between preoperatively planned implant size and intraoperatively implanted implant size. The method includes determining a statistically expected implant size deviation from a planned implant size for each implant included in a plurality of patient-specific arthroplasty kits prepared for a shipment to the medical facility using the database. A backup kit of backup implants is assembled for the shipment. The number and size of the backup implants is determined from the statistically expected implant size deviations.
Description
- The present teachings provide a backup kit including backup arthroplasty implants for a shipment of a plurality of patient-specific arthroplasty kits for a plurality of corresponding arthroplasty procedures at the same medical facility. The patient-specific arthroplasty kits generally include patient-specific alignment guides, custom and non-custom implants and other instruments for use during an arthroplasty procedure. The patient-specific alignment guides (and patient-specific implants, when used) are designed and constructed preoperatively based on three-dimensional digital images of the patient's joint that is scheduled to undergo arthroplasty. The digital images of the patient's joint can be reconstructed from medical scans of the patient using commercially available CAD (Computer Aided Design) and/or other imaging software.
- The present teachings provide a method for preparing a backup kit for a shipment of patient-specific arthroplasty kits for corresponding arthroplasty procedures scheduled at the same medical facility. The method includes providing a database with data from completed arthroplasty procedures that were performed using patient-specific arthroplasty kits. The database includes comparisons between preoperatively planned implant size and intraoperatively implanted (actual) implant size. A statistically expected implant size deviation from a planned implant size for each implant included in the shipment is determined using the database. A backup kit of backup implants is assembled for the shipment. The number and size of the backup implants is determined from the statistically expected implant size deviations.
- The present teachings also provide a backup kit for a plurality of patient-specific arthroplasty procedures scheduled at the same medical facility. The backup kit includes a plurality of backup implants selected for a shipment of a plurality of patient-specific arthroplasty kits for the medical facility. Each patient-specific arthroplasty kit is configured for corresponding arthroplasty procedures at the same medical facility. The number and size of the backup implants is determined from statistically expected implant size deviations from planned implant sizes in the corresponding arthroplasty kits using a compliance database. The compliance database includes data from completed arthroplasty procedures performed using patient-specific arthroplasty kits. The compliance database includes comparisons between preoperatively planned implant sizes and intraoperatively implanted implant sizes.
- Further areas of applicability of the present teachings will become apparent from the description provided hereinafter. It should be understood that the description and specific examples are intended for purposes of illustration only and are not intended to limit the scope of the present teachings.
- The drawings described herein are for illustrative purposes only of selected embodiments and not all possible implementations, and are not intended to limit the scope of the present disclosure.
-
FIG. 1 is a schematic view of an exemplary patient-specific arthroplasty kit; -
FIG. 2 is a schematic view of a shipment of a plurality of patient-specific arthroplasty kits similar to the patient-specific arthroplasty kit ofFIG. 1 according to the present teachings; -
FIG. 3 is a schematic view of a backup kit for the shipment ofFIG. 2 according to the present teachings; -
FIG. 4 is a flowchart for a method according to the present teachings; and -
FIG. 5 is an exemplary partial listing of a compliance database according to the present teachings. - Corresponding reference numerals indicate corresponding parts throughout the several views of the drawings.
- The following description is merely exemplary in nature and is in no way intended to limit the present teachings, applications, or uses. For example, although some of the present teachings are illustrated for a knee implant, the present teachings can be used for any orthopedic implant.
- The present teachings provide a backup kit that includes backup arthroplasty implants for a shipment of a plurality of patient-specific arthroplasty kits for use at the same medical facility for a plurality of corresponding arthroplasty procedures. The patient-specific arthroplasty kits generally include patient-specific guides, custom and non-custom implants and other instruments for use during an arthroplasty procedure such as, for example, cutting guides, drill guides, cutting blocks, fixation pins, etc. The patient-specific guides and/or patient-specific implants, if used, are designed and constructed preoperatively based on three-dimensional digital images of the patient's joint that is scheduled to undergo arthroplasty. The backup kit includes backup implants of various sizes to be included with each particular shipment. The number and sizes of the backup implants in the backup kit are determined from a statistical analysis of patient-outcomes that are stored in a compliance database, as discussed below.
- Generally, patient-specific devices including implants and/or patient-specific alignment guides, resection guides or other instruments can be designed preoperatively using computer-assisted imaging methods. Three-dimensional digital images of the patient's joint anatomy can be reconstructed from MRI, CT, ultrasound, X-ray, or other medical scans of the patient's anatomy. Various CAD programs and/or other software can be utilized for three-dimensional digital image reconstruction, such as, for example, software commercially available from Materialise USA, Plymouth, Mich.
- Various pre-operative planning methods and patient-specific devices are disclosed in commonly assigned U.S. patent application Ser. No. 11/756,057, filed May 31, 2007, U.S. patent application Ser. No. 11/971,390, filed on Jan. 9, 2008, U.S. patent application Ser. No. 12/025,414, filed on Feb. 4, 2008, U.S. patent application Ser. No. 12/039,849, filed Feb. 29, 2008; U.S. patent application Ser. No. 12/211,407, filed Sep. 16, 2008; U.S. patent application Ser. No. 12/103,824, filed Apr. 16, 2008; U.S. patent application Ser. No. 12/371,096, filed Feb. 13, 2009, U.S. patent application Ser. No. 12/483,807, filed Jun. 12, 2009; U.S. patent application Ser. No. 12/872,663, filed Aug. 31, 2010, U.S. patent application Ser. No. 12/973,214, filed Dec. 20, 2010, and U.S. patent application Ser. No. 12/978,069, filed Dec. 23, 2010. The disclosures of the above patent applications are incorporated herein by reference.
- In the preoperative planning stage for an arthroplasty procedure, a preoperative surgical plan is formulated for a specific patient with interactive input from the patient's surgeon or other medical professional. Imaging data of the relevant joint anatomy of a patient can be obtained at a medical facility or doctor's office using any of the medical imaging methods described above. The imaging data can include, for example, various medical scans of a relevant joint portion or other relevant portion of the patient's anatomy, as needed for joint or other anatomy modeling and, optionally, for determination of an implant alignment axis or for other alignment purposes. The imaging data thus obtained and other associated information can be used to construct a three-dimensional computer (digital) image of the joint or other portion of the anatomy of the patient, such as, the hip joint, knee joint, etc. The three-dimensional digital image of the patient's anatomy is also used to formulate a preoperative surgical plan for the patient including, for example, location and orientation of resections, removal of osteophytes or other protrusions, mechanical alignment, deformity correction, ligament balancing, or other preoperative planned procedures The preoperative surgical plan can also include the design and construction of patient-specific alignment guides, resection guides or other patient-specific instruments, and, optionally, the design and construction of patient-specific implants. Further, the preoperative surgical plan can include the determination and selection of particular sizes of non-custom implants, digital images of which can be viewed and compared relative to the three-dimensional digital image of the patient's anatomy on a digital display.
- Generally, the patient-specific devices, whether implants or instruments, are configured to match at least a portion of a joint anatomy of a specific patient and are generally designed and configured using computer modeling based on the patient's reconstructed three-dimensional digital image of the patient's corresponding joint anatomy. Each patient-specific device includes a three-dimensional patient-specific surface that is configured to conformingly contact and match a corresponding surface of the patient (with or without cartilage or other soft tissue), using the reconstructed three-dimensional digital image of the patient's anatomy and the computer methods discussed above. In this respect, a patient-specific device can register and nestingly mate with the corresponding bone surface (with or without articular cartilage) of the specific patient in only one position.
- The three-dimensional digital model of the patient's anatomy can be viewed on a computer display or other electronic screen and can also be reproduced as a hard copy on film or other medium and viewed by direct or indirect or backlight illumination. The digital model can be sized for viewing on any appropriate screen size (including handheld mobile devices, such as smart phones, PDAs or tablets) and may be cropped, rotated, etc., as selected by the individual (e.g., the surgeon) viewing the screen.
- The surgeon's review of the surgical plan may include implant selection, and/or a request for one or more patient-specific instruments, such as alignment guides, resection guides or other instruments to be used with the selected implant. The patient-specific devices can be manufactured by rapid prototyping methods, such as stereolithography or other similar methods or by CNC milling, or other automated or computer-controlled machining or robotic methods. The patient-specific instruments, the selected implants and optionally other disposable instruments can be sterilized, assembled in a patient-specific kit and forwarded to the surgeon or the surgeon's medical facility for implantation. The selected implants can be non-custom implants of a size determined and approved by the surgeon in the preoperative plan for the patient.
- Many medical facilities (or surgeons) place orders requesting multiple patient-specific kits for use by the same or different surgeons at the same facility for procedures scheduled for the same day or a few days apart. Referring to
FIG. 2 , an omnibus patient-specific kit assembly 200 can include a plurality of patient-specific arthroplasty kits 100 (100A, 1008, 100C, etc.) for shipment to a single medical facility. Each patient-specific arthroplasty kit - The present teachings provide a method to design and prepare a backup kit 300 (see
FIG. 3 ) for an entire bulk order or shipment that includes several patient-specific arthroplasty kits, as discussed below. Accordingly, the present teachings reduce weight, expense and unnecessary backup implant components for each patient-specific kit while providing the surgeon(s) and or the facility with sufficient oversize or undersize implants for the totality of the procedures, rather than for each single procedure. The determination of the number and size of additional or backup implants to be included in thebackup kit 300 is made using statistical analysis of the size outcomes previous procedures which are stored in a compliance database, as described below. Duplicate size backup implants can also be included. - An exemplary patient-
specific arthroplasty kit 100 for a knee procedure is shown inFIG. 1 . It will be appreciated that similar kits can be prepared for other joints, such as the hip joint, shoulder joint or other joints. The patient-specific arthroplasty kit 100 can include, for example, a patient-specificfemoral alignment guide 110, a patient-specifictibial alignment guide 118, afemoral drill guide 112, atibial drill guide 120, a femoraldistal cutting block 114, atibial cutting block 130, a four-in-onefemoral cutting block 116, and atibial template 122. The patient-specific alignment guides 110, 118 are single-use guides and disposable. Detailed description of the patient-specific alignment guides and associated methods can be found in the patent applications referenced above (and incorporated by reference herein). The various drill guides and cutting blocks can be re-sterilizable and reusable, although disposable drill guides, cutting blocks and other tools can also be designed. Additionally, a set of trochar pins 132 and a set of spring drill pins 134 can be included. Depending on the surgeon's preferences, additional tools and/or medical products and supplies can be included, such as cutting blades, bone cement, biologics, etc. - The patient-
specific arthroplasty kit 100 can include a set of arthroplasty implants, such as, for example, afemoral implant 150, abearing 152 and atibial implant 154, for an exemplary total knee arthroplasty procedure, or other implant components depending on the surgical procedure and the surgeon's preference. The arthroplasty implants can be either patient-specific or non-custom implants. Semi-custom arthroplasty implants, i.e., implants including some patient-specific features and some standard, non-custom features can also be used, as described, for example, in commonly assigned U.S. patent application Ser. No. 12/872,663, filed Aug. 31, 2010, referenced above (and incorporated by reference herein). - Referring to
FIGS. 1-3 , the implants orimplant components specific arthroplasty kit 100 can be non-custom components of a size selected during the preoperative plan for the patient. Predominantly, the selected or planned implant size is found to be a match and no change in implant size is required intraoperatively. For the few cases that the implant-size is found intraoperatively, for various reasons, not to be the best match, a best match implant can be found in the preoperativelyprepared backup kit 300 with a degree of a built-in or preoperatively determined degree probability, using acompliance database 500, as discussed below. Thebackup kit 300 can include a predetermined number of backup implant components. For illustration purposes only, three different sizes for eachimplant component single backup kit 300 that accompanies the patient-specific kit assembly 200. The selection of number and sizes the implant components to be included in the backup kit is discussed below with reference toFIGS. 4 and 5 . - An exemplary (but not necessary representative) portion of a
compliance database 500 is illustrated inFIG. 5 . Thecompliance database 500 can be generated from information collected for each arthroplasty procedure for which a patient-specific arthroplasty kit was provided. Thecompliance database 500 can include the planned implant size, as well as the actual implant size that was eventually used. Information collected and provided by thedatabase 500 can also include date of the procedure, patient Identification, surgeon name, the side (R right, L left) for the procedure and other characteristics of the patient, such as, for example, weight, ethnicity or race, gender, age or other characteristics that may be of significance in selecting implant size or that can be factors for a size deviation or mismatch. - The number of procedures scheduled for the same date can vary, the norm being several procedures per day, although a single procedure or eleven or twelve procedures in a single day are not uncommon. In the exemplary illustration of
FIG. 5 , the implant sizes presented are for afemoral component 150 of the Vanguard® Knee Complete System, commercially available from Biomet Manufacturing Corp., Warsaw, Indiana. The available sizes correspond to mediolateral (ML) dimensions of the femur in mm. The interval between sizes for the Vanguard® Knee, for example, is 2.5 mm for sizes ranging from size 55 to size 75. A size 80 mm is also available. Similarly, nine sizes are available for thetibial component 154 and seven sizes for thebearing 152 for the Vanguard® Knee. Implanting the wrong size, i.e., implant mis-sizing for thefemoral implant 150 can result in excessive mediolateral overhang, especially in women, and can cause over-tightening of the knee capsule when a larger size is used. Providing backup sizes (one size larger or one size smaller than a planned size) for each and every implant in the shipment to the same facility can be costly, wasteful and inefficient both in bulk and weight. Thecompliance database 500 can be created and used to reduce the number of backup implants for the shipment, while still providing a high probability that the intraoperatively determined implant size is the planned size or is included in the backup kit. - The partial data presented chronologically in
FIG. 5 may be somewhat misleading in that they show a higher proportion of mismatches between planned and actual implant sizes than is the case when all the available data is considered for a longer period of time. For example, Applicant's data for a period ranging from Dec. 1, 2008 to Jun. 19, 2009 can be summarized as follows: 54 mismatches or implant size deviations for a total of 397 arthroplasty procedures, or a 13.8% (54/398) mismatch (or deviation) rate. From the 54 mismatches, in 44 mismatches the planned size was oversized (one size too big; rate 44/397=0.11) and in 11 mismatches the planned size was undersized (one size too small; rate 11/397=0.28). It is noted, however, that, according to the present teachings, thecompliance database 500 is updated frequently or for each procedure performed, and that the contents of thebackup kit 300 can then be determined by statistical analysis of the updatedcompliance database 500. For example, if N patient-specific arthroplasty kits 100 are required for a single day D in a medical facility M, and each patient-specific arthroplasty kit 100 includes one implant of the type 150 (femoral knee component), then the database is analyzed to determine the proportion of higher and lower sizes that may be needed for a set of N implants oftype 150 and having a particular size. The statistical analysis, in its simplest form, may be based on percentages, or may include other considerations, such as reduction of mismatches over time as the technology evolves, patient characteristics, surgeon preferences, various weighing factors and other parameters. The statistical analysis can also include a specified contingency or probability coverage, i.e., what percentage of all mismatch cases should be covered, such as, for example from 98% or higher. Error analysis, standard deviation analysis, data reliability analysis and other statistical methods and algorithms known in the art can also be considered in the calculations. It is also noted that thecompliance database 500 can depend on the characteristics of the implants and instruments used and can, therefore, vary from manufacturer to manufacturer. Accordingly, arelevant compliance database 500 can be generated or otherwise available to be accessed for determining the backup kit for a particular manufacturer according to the present teachings. - As an illustration, the surgical schedule for the date Dec. 8, 2008 includes two R (right side) components of size 70 and three R components of size 67.5. For these five components, based on the 11% chance of oversize determined from the
compliance database 500, one backup implant of size R67.5 for planned implant size R70 and one backup implant of size R65 for planned size R67.5 may be provided in thebackup kit 300. Duplicative backup implants (backup implant has same size as planned implant size) can also be included in thebackup kit 300 to account for loss of sterilization, mishandling or other mishaps and accidents at the medical facility. The number of duplicative backup implants can be determined from statistical analysis of data included in thecompliance database 500, or from other historical records or databases, or from surgeon and/or medical facility preferences and requirements. - In some embodiments, the
backup kit 300 may be prepared for all the arthroplasty procedures performed at the same medical facility M for a different period of time, a week, for example. For the week of Dec. 1, 2008 to Dec. 5, 2008, for example, five L67.5 implants were planned. One backup implant of size L65 can be included in the backup kit based on the 11% rate of oversize mismatch. If the undersize mismatch rate is only 2.8%, as in data presented above, aseparate backup kit 300 that includes bigger sizes for the lower chance of undersize planned implants may be maintained at facility M to be accessed as needed and replenished periodically. A backup kit with larger sizes for undersize planned implants can be prepared, for example, using estimates based on anticipated needs for longer periods of time, such as, per month, quarterly, etc. Further, the rate of mismatch can be calculated from the database for each particular size. For example, if the rate of oversize mismatch is x % for a particular implant size N, then for every hundred implants of size N (in mm) in one shipment (a patient-specific kit assembly 200) of patient-specific arthroplasty kits 100, an x number of implants of one size lower than N, i.e., N-2.5, can be included in thebackup kit 300. If only ten implants are included in thebackup kit 300, then x/10 implants of the smaller size are included in thebackup kit 300. The statistically determined number of backup implants for each planned implant size in the shipment (or patient-specific kit assembly) 200 of patient-specific arthroplasty kits 100 is not necessarily an integer and can be rounded up or down to the nearest integer number. - It will be appreciated that other backup implants can be included in the
backup kit 300, above and beyond those that can be statistically required. For example, a surgeon may require a larger size backup implant for any planned size below 60 mm. Such considerations can be used to modify thebackup kit 300 after the backup implant components have been determined by statistical analysis. In some cases, the contents determined by statistical analysis may already satisfy the surgeon's or the medical facility's additional requirements. - Referring to
FIG. 4 , a flowchart of a method of assembling abackup kit 300 according to the present teachings is illustrated. At block 400 acompliance database 500 is created or otherwise provided for access. Atblock 402, an omnibus patient-specific kit assembly orshipment 200 is prepared for a facility M. As discussed above, the patient-specific kit assembly 200 includes a plurality of patient-specific arthroplasty kits 100 that are scheduled to be performed on the same day or within a specified number of days, such as, for example, on the same forthcoming week. The sizes of the various implants of the patient-specific kit assembly 200 and corresponding patient-characteristic can be identified atblock 404. A statistical analysis can be performed atblock 406 to determine the likelihood of deviation or mismatch between preoperatively planned implant sizes and actual implant sizes as predicted by thecompliance database 500. Based on the results of the statistical analysis, expected deviations in implant size, i.e., the number of planned implants expected to be oversized or undersized can be determined atblock 408 and a backup kit of implants can then be assembled atblock 410. Thecompliance database 500 can be updated at 412 with data from the new arthroplasty procedures that have been performed. - As discussed above, a
compliance database 500 of preoperatively planned and actual (intraoperatively selected) implants can be created from data collected from patient-specific preoperative plans and actual arthroplasty usage. The database provides details of mismatches or deviations between a planned implant size and an actually used implant size. The information in the database can be statistically analyzed to help determine the number and sizes of extra of backup implants to be included in abackup kit 300 for a plurality of arthroplasty procedures that are planned preoperatively and include patient-specific arthroplasty kits 100. - Example embodiments are provided so that this disclosure is thorough, and fully conveys the scope to those who are skilled in the art. Numerous specific details are set forth, such as examples of specific components, devices, and methods, to provide a thorough understanding of embodiments of the present disclosure.
- It will be apparent to those skilled in the art that specific details need not be employed, that example embodiments may be embodied in many different forms and that neither should be construed to limit the scope of the disclosure. In some example embodiments, well-known processes, well-known device structures, and well-known technologies are not described in detail. Accordingly, individual elements or features of a particular embodiment are generally not limited to that particular embodiment, but, where applicable, are interchangeable and can be used in a selected embodiment, even if not specifically shown or described. The same may also be varied in many ways. Such variations are not to be regarded as a departure from the disclosure, and all such modifications are intended to be included within the scope of the disclosure.
Claims (15)
1. A method for preparing a backup kit for a plurality of patient-specific arthroplasty procedures scheduled at the same medical facility comprising:
providing a database having data from completed arthroplasty procedures using patient-specific arthroplasty kits, the database including comparisons between preoperatively planned implant sizes and intraoperatively implanted implant sizes;
determining a statistically expected implant size deviation from a planned implant size for each implant included in a plurality of patient-specific arthroplasty kits prepared for a shipment to the medical facility using the database; and
assembling a backup kit of backup implants for the shipment, wherein the number and size of the backup implants is determined from the statistically expected implant size deviations.
2. The method of claim 1 , further comprising updating the database with intraoperatively implanted implant size for each patient-specific arthroplasty kit after a corresponding arthroplasty procedure is completed.
3. The method of claim 1 , further comprising assembling the plurality of patient-specific arthroplasty kits for the medical facility.
4. The method of claim 3 , further comprising including in each patient-specific arthroplasty kit a patient-specific alignment guide.
5. The method of claim 4 , further comprising including in each patient-specific arthroplasty kit a non-custom implant.
6. The method of claim 1 , wherein the size of at least one backup implant differs by a size interval of 2.5 mm from the planned implant size.
7. The method of claim 1 , wherein the backup kit includes knee implants.
8. The method of claim 1 , wherein the planned period of time is a single day.
9. The method of claim 1 , wherein the planned period of time is a single week.
10. A method for preparing a backup kit for a plurality of patient-specific arthroplasty procedures scheduled at the same medical facility comprising:
assembling a shipment of a plurality of patient-specific arthroplasty kits scheduled for arthroplasty procedures at the same medical facility within a planned period of time, each arthroplasty kit including a patient-specific alignment guide and a non-custom implant;
accessing a database of completed arthroplasty procedures using patient-specific arthroplasty kits, the database indicating deviations between preoperatively planned implant sizes and intraoperatively implanted implant sizes;
determining from the database a statistically expected size deviation for each implant size in the shipment; and
assembling a backup kit of backup implants for the shipment, the number and size of the backup implants included in the backup kit determined from the statistically expected implant size deviations.
11. The method of claim 10 , wherein the backup kit includes knee implants.
12. The method of claim 10 , wherein each patient-specific arthroplasty kit in the shipment includes a patient-specific femoral alignment guide.
13. The method of claim 12 , wherein each patient-specific arthroplasty kit in the shipment includes a patient-specific tibial alignment guide.
14. The method of claim 13 , wherein each patient-specific arthroplasty kit in the shipment includes a non-custom knee femoral and a non-custom knee tibial implant.
15-24. (canceled)
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Also Published As
Publication number | Publication date |
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US20200060691A1 (en) | 2020-02-27 |
US20180368858A1 (en) | 2018-12-27 |
US11253269B2 (en) | 2022-02-22 |
US10492798B2 (en) | 2019-12-03 |
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