US2308484A - Catheter - Google Patents
Catheter Download PDFInfo
- Publication number
- US2308484A US2308484A US251096A US25109639A US2308484A US 2308484 A US2308484 A US 2308484A US 251096 A US251096 A US 251096A US 25109639 A US25109639 A US 25109639A US 2308484 A US2308484 A US 2308484A
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- Prior art keywords
- catheter
- section
- rubber
- preformed
- sleeve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
- B29C41/14—Dipping a core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1027—Making of balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1027—Making of balloon catheters
- A61M25/1029—Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2021/00—Use of unspecified rubbers as moulding material
Definitions
- Our present invention relates to the manufacture of inflatable catheters of the type disclosed in U. 5.
- Patent No. 2,043,630 has particular reference to an improved catheter and a novel method for manufacture thereof.
- a further object of the invention is to provide a catheter having a stronger inflatable balloon section.
- Another object is to provide a catheter having a preformed inflatable section of desired shape.
- Still another object of the invention is to pro-- vide an inflatable balloon section for a catheter having reinforced ends.
- the invention consists of a novel method of manufacture and a novel catheter obtained thereby, more fully disclosed in the detailed description following, in conjunction with the accompanying drawing, and more speciflcally defined in the claims appended thereto.
- Fig. 1 is a view in section of the novel catheter, the dotted lines indicating the ballon when inflated.
- Fig. 2 is a sectional perspective detail showing a partially formed cat
- Fig. 3 is a perspective detail, partly broken away, of an inflatable balloon section before assembly.
- Fig. 4 is a view similar to Fig. 2, the inflatable section being assembled
- Fig. 5 is a similar view after the-catheter dipping has been completed
- Fig. 6 is a view similar to Fig. 4, showing the manner of reinforcing the balloon ends;
- Fig. 7 is a view of a preformed balloon section
- Fig. 8 is a similar view of a different preformed section.
- Fig. 9 is a view showing a pre-tensioned balloon section.
- a catheter base is first provided. as by dipp a separate inflatable section is then applied thereto, and the catheter is then completed, as-by dipping in. to coat both the base and the applied section, whereby a strong, sturdy inflatable catheter is obtained.
- the catheter I Ii includes a body portion I I having a central passageway I2, and terminating in a flmnel end I3, the wall I4 having flow ports I 5 at the distal end and having an inflation channel Ii therein which communicates through a port I! with a recess I8 haw'ng an inflatable balloon section I9.
- the inflation channel passes outwardly through an extension 20 and communicates with a funnelshaped inflating end 2
- the catheter body 22 is first built up on a form of metal or the like, as by dipping in a coagulant solution and a latex solution, preferably repeatedly, until a desired thickness of wall is obtained containing the inflation channel, described as in U..S. Patent No. 2,043,630, the port opening I1 then being formed, by burning with a hot wire or needle. Then a preformed tubular or sleeve section 23, see Fig. 3, which may have strengthening ribs 24 of any desired length and direction, is moistened with a wetting agent, the body portion being also moistened, and the sleeve is slide over the end of the body portion to cover the inflation port.
- the preferred wetting agent is water containing dissolved soap, but any suitaable wetting agent may be used.
- the wetting agent and any foreign solid substances that might have adherred, as by washing, and an additional coat or coats of rubber are then applied by dipping until the desired thickness of balloon is obtained.
- the sleeve is thus made part of the catheter structure by the provision of an outer wall which looks all the parts together.
- the balloon is then air dried for a short time, and air is forced through the inflation channel and put to slightly distend the balloon, so as to positively prevent any adhesion during the drying step.
- the catheter is now partly dried, and is then leached and dried for a relatively long period of time.
- the sleeve When the sleeve is first placed on the catheter. it is preferably stretched, .the ends being designed to grip the catheter body portion; if necessary, a small amount of rubber adhesive may be used on the sleeve ends. If one or both ends of the sleeve are desired reinforced, a reinforcing band 25, see Fig. 6, is placed on the sleeve end, so as to add an additional thickness of rubber, the band tightly gripp ng the sleeve end and the adiacent catheter parts, and being embedded in the additional dipped layers, it being preferred to use a narrow band.
- the sleeve may be of any desired shape, as it 2 asoaass is preformed; a top shape such as indicated at I! inFigJLorabulbshape suchasshown at 21 in Fig. 8 may be used, reinforcing ribs 28 being provided of any size and direction.
- the shaped sleeve is made of pie-vulcanized rubber, the main body of the catheter being of unvulcanized rubbe: which has been distended sligh the outer surfacebeingdried. andthenplaeedonamandril, on which it is stretched, dried, and vulcanized while in the stretched position.
- a chemical treating a ent such as described in Patent No. 2,051,849, is preferably used on the catheter to prevent adhering of the sleeve to the catheter; to remove any tackiness from the sleeve inside surface, the sleeve may be turned inside out, and dipped into a treating solution while the lower end is kept cloud by any suitable means, as for example by the fingers of the operator. Treating solution may also be forced through the inflating passage and into the balloon to prevent adherence after the sleeve has been placed on the catheter body, and either before or after the additional dipping coats are put on.
- a presleeve permits placing the sleeve under tension when positioned on the catheter, each end being secured to the catheter body, additional coats of rubber then being applied on either end of the catheter as well as on the sleeve ends, but preferably not on the main body portion of the sleeve forming the balloon.
- This modified construction produces a catheter which has no loose or baggy ends or depressions at each end, the catheter instead always remaining distended intermediate the ends, which merge into the catheter body as indicated at II in Fig. 9.
- the method of forming a tubular article with a wall recess comprising the steps of coating a form with rubber in solution to provide a tubular body, wetting the tubular body, wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section under tension on the wetted tubular body. and coating the assemblyv with rubber in solution to lock the preformed tubular section to the tubular body.
- the method of forming an inflatable balloon catheter comprising the steps of coating a form with rubber in solution, placing an inflation tube thereon. again coating the form and tube with rubber in solution to provide a catheter body having an inflation passageway, opening the distal end of the tube through the second coat, wetting the catheter bo y. wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section on the wetted c:.theter body with the open end of the inflation tube intermediate the ends of the preformed section, and coating the assemblywith rubber in solution to lock the tubular section to the catheter body.
- the method of forming an inflatable catheter comprising the steps ofcoating a form arrangement with rubber in solution to provide a catheter body having an inflation eway in the wall thereof, opening the distal inflation passageway end, wetting the catheter body. wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section on the wetted catheter body with the open end of the inflation passageway intermediate the ends of the preformed tubular section, and coating with rubberin solution over'at least the ends of the tubular section and the adjacent portions of the catheter body to lock the ends of the tubular section .to the catheter body.
Description
Jan. 19, 1943.
J. M. AUZIN ETAL' CATHETER Filed Jan. 16, 1959 Patented Jan. 19, 1943 OFFICE ca'mn'ran John M. mum and Morton u. Zinch, Warwick,
B. 1., assignors to Davol Rubber Island corporation of Rhode Application January 16, 1939, Serial No. 251,096
Claims.
Our present invention relates to the manufacture of inflatable catheters of the type disclosed in U. 5. Patent No. 2,043,630, and has particular reference to an improved catheter and a novel method for manufacture thereof.
It is the principal object of our invention to simplify the manufacture of inflatable catheters.
A further object of the invention is to provide a catheter having a stronger inflatable balloon section.
Another object is to provide a catheter having a preformed inflatable section of desired shape.
Still another object of the invention is to pro-- vide an inflatable balloon section for a catheter having reinforced ends.
With the above and other objects and advantageous features in view, the invention consists of a novel method of manufacture and a novel catheter obtained thereby, more fully disclosed in the detailed description following, in conjunction with the accompanying drawing, and more speciflcally defined in the claims appended thereto.
In the drawing:
Fig. 1 is a view in section of the novel catheter, the dotted lines indicating the ballon when inflated.
Fig. 2 is a sectional perspective detail showing a partially formed cat Fig. 3 is a perspective detail, partly broken away, of an inflatable balloon section before assembly.
Fig. 4 is a view similar to Fig. 2, the inflatable section being assembled;
Fig. 5 is a similar view after the-catheter dipping has been completed;
Fig. 6 is a view similar to Fig. 4, showing the manner of reinforcing the balloon ends;
Fig. 7 is a view of a preformed balloon section;
Fig. 8 is a similar view of a different preformed section; and
Fig. 9 is a view showing a pre-tensioned balloon section.
It has been found desirable to provide inflatable catheters with preformed inflatable sections. whereby the sections may be of any shape desired and may have strengthening ribs of any desired type. This construction ensures a stronger bal-,
loon secfion, while maintaining the thickness of the completed catheter to a desired size. To this end, a catheter base is first provided. as by dipp a separate inflatable section is then applied thereto, and the catheter is then completed, as-by dipping in. to coat both the base and the applied section, whereby a strong, sturdy inflatable catheter is obtained.
companyla Referring to the drawing, the catheter I Ii includes a body portion I I having a central passageway I2, and terminating in a flmnel end I3, the wall I4 having flow ports I 5 at the distal end and having an inflation channel Ii therein which communicates through a port I! with a recess I8 haw'ng an inflatable balloon section I9. The inflation channel passes outwardly through an extension 20 and communicates with a funnelshaped inflating end 2| adapted to be connected to a source of fluid imder pressure.
In manufacturing the novel catheter, the catheter body 22, see Fig. 2, is first built up on a form of metal or the like, as by dipping in a coagulant solution and a latex solution, preferably repeatedly, until a desired thickness of wall is obtained containing the inflation channel, described as in U..S. Patent No. 2,043,630, the port opening I1 then being formed, by burning with a hot wire or needle. Then a preformed tubular or sleeve section 23, see Fig. 3, which may have strengthening ribs 24 of any desired length and direction, is moistened with a wetting agent, the body portion being also moistened, and the sleeve is slide over the end of the body portion to cover the inflation port. The preferred wetting agent is water containing dissolved soap, but any suitaable wetting agent may be used.
The wetting agent and any foreign solid substances that might have adherred, as by washing, and an additional coat or coats of rubber are then applied by dipping until the desired thickness of balloon is obtained. The sleeve is thus made part of the catheter structure by the provision of an outer wall which looks all the parts together.
The balloon is then air dried for a short time, and air is forced through the inflation channel and put to slightly distend the balloon, so as to positively prevent any adhesion during the drying step. The catheter is now partly dried, and is then leached and dried for a relatively long period of time.
When the sleeve is first placed on the catheter. it is preferably stretched, .the ends being designed to grip the catheter body portion; if necessary, a small amount of rubber adhesive may be used on the sleeve ends. If one or both ends of the sleeve are desired reinforced, a reinforcing band 25, see Fig. 6, is placed on the sleeve end, so as to add an additional thickness of rubber, the band tightly gripp ng the sleeve end and the adiacent catheter parts, and being embedded in the additional dipped layers, it being preferred to use a narrow band.
The sleeve may be of any desired shape, as it 2 asoaass is preformed; a top shape such as indicated at I! inFigJLorabulbshape suchasshown at 21 in Fig. 8 may be used, reinforcing ribs 28 being provided of any size and direction. The shaped sleeve is made of pie-vulcanized rubber, the main body of the catheter being of unvulcanized rubbe: which has been distended sligh the outer surfacebeingdried. andthenplaeedonamandril, on which it is stretched, dried, and vulcanized while in the stretched position.
A chemical treating a ent, such as described in Patent No. 2,051,849, is preferably used on the catheter to prevent adhering of the sleeve to the catheter; to remove any tackiness from the sleeve inside surface, the sleeve may be turned inside out, and dipped into a treating solution while the lower end is kept cloud by any suitable means, as for example by the fingers of the operator. Treating solution may also be forced through the inflating passage and into the balloon to prevent adherence after the sleeve has been placed on the catheter body, and either before or after the additional dipping coats are put on.
The use of a presleeve permits placing the sleeve under tension when positioned on the catheter, each end being secured to the catheter body, additional coats of rubber then being applied on either end of the catheter as well as on the sleeve ends, but preferably not on the main body portion of the sleeve forming the balloon. This modified construction produces a catheter which has no loose or baggy ends or depressions at each end, the catheter instead always remaining distended intermediate the ends, which merge into the catheter body as indicated at II in Fig. 9.
While we have described specific constructional embodiments of the invention, it is obvious that changes in the arrangement and shape of the parts-andintheeharacterofthematerialsused may be made to suit the requirements for different articles embodyin the invention, without departing from the spirit and the scope of the invention, as deflned in the appended claims.
We claim:
1. The method of forming a tubular article with a wall recess. comprising the st m of coatin: a form with rubber in solution to provide a tubular body, wetting the tubular body, wetting a preformed tubular section of vulcanized rubber,
placing thewetted preformed tubular section on thewetted tubular body, and coating the assembly with rubber in solution to lock the preformed tubular section to the tubular body.
2. The method of forming a tubular article withawallrecess,eomprisingthestepsofcoating a form with rubber in solution to provide a tubularbody,wettin'gthetubularbody,wettinga preformed tubular section of vulcaniled rubber. placing the wetted preformed tubularsection on thewettedtubularbodyafterflrstaimlyingrubbereementtotheinnersurfaeeoftheendsofthe preformed tubular section, and coating the assembly with rubber in solution to lock the pre-.
' formed tubular section to the tubular body.
3. The method of forming a tubular article with a wall recess, comprising the steps of coating a form with rubber in solution to provide a tubular body, wetting the tubular body, wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section under tension on the wetted tubular body. and coating the assemblyv with rubber in solution to lock the preformed tubular section to the tubular body.
4. 'The method of forming an inflatable balloon catheter comprising the steps of coating a form with rubber in solution, placing an inflation tube thereon. again coating the form and tube with rubber in solution to provide a catheter body having an inflation passageway, opening the distal end of the tube through the second coat, wetting the catheter bo y. wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section on the wetted c:.theter body with the open end of the inflation tube intermediate the ends of the preformed section, and coating the assemblywith rubber in solution to lock the tubular section to the catheter body.
' 5. The method of forming an inflatable catheter comprising the steps ofcoating a form arrangement with rubber in solution to provide a catheter body having an inflation eway in the wall thereof, opening the distal inflation passageway end, wetting the catheter body. wetting a preformed tubular section of vulcanized rubber, placing the wetted preformed tubular section on the wetted catheter body with the open end of the inflation passageway intermediate the ends of the preformed tubular section, and coating with rubberin solution over'at least the ends of the tubular section and the adjacent portions of the catheter body to lock the ends of the tubular section .to the catheter body.
some M. suzm. non-run n; zmcx.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US251096A US2308484A (en) | 1939-01-16 | 1939-01-16 | Catheter |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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US251096A US2308484A (en) | 1939-01-16 | 1939-01-16 | Catheter |
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US2308484A true US2308484A (en) | 1943-01-19 |
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US251096A Expired - Lifetime US2308484A (en) | 1939-01-16 | 1939-01-16 | Catheter |
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Cited By (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2481488A (en) * | 1946-10-19 | 1949-09-13 | Davol Rubber Co | Method of making inflatable catheters having preformed balloon sacs |
US2548602A (en) * | 1948-04-09 | 1951-04-10 | Greenburg Leonard | Inflatable dilator |
US2637320A (en) * | 1950-07-22 | 1953-05-05 | Greenberg Emanuel Martin | Obstetrical forceps |
US2693191A (en) * | 1951-07-16 | 1954-11-02 | Davol Rubber Co | Incontinence urinal balloon plug |
US2762737A (en) * | 1956-09-11 | Method of manufacture of expanders | ||
US2892458A (en) * | 1956-07-31 | 1959-06-30 | Kathleen T Auzin | Catheter |
US2972779A (en) * | 1954-06-07 | 1961-02-28 | Baxter Don Inc | Plastic tubing process |
US3435826A (en) * | 1964-05-27 | 1969-04-01 | Edwards Lab Inc | Embolectomy catheter |
US3850720A (en) * | 1972-02-01 | 1974-11-26 | Searle & Co | Method of bonding a balloon sleeve to a catheter lumen tube |
US3861972A (en) * | 1970-08-24 | 1975-01-21 | Johnson & Johnson | Intravenous catheter |
US4018231A (en) * | 1974-01-24 | 1977-04-19 | Airco, Inc. | Disposable balloon type catheter |
US4737219A (en) * | 1985-02-12 | 1988-04-12 | Becton, Dickinson And Company | Method for bonding polyurethane balloons to multilumen catheters |
US5078725A (en) * | 1989-11-09 | 1992-01-07 | C. R. Bard, Inc. | Balloon catheter and techniques for dilating obstructed lumens and other luminal procedures |
US5098379A (en) * | 1990-01-10 | 1992-03-24 | Rochester Medical Corporation | Catheter having lubricated outer sleeve and methods for making and using same |
US5137671A (en) * | 1990-01-10 | 1992-08-11 | Rochester Medical Corporation | Methods of making balloon catheters |
EP0567976A2 (en) * | 1992-04-27 | 1993-11-03 | Minnesota Mining And Manufacturing Company | Retrograde coronary sinus catheter |
US5261896A (en) * | 1990-01-10 | 1993-11-16 | Rochester Medical Corporation | Sustained release bactericidal cannula |
US5269770A (en) * | 1990-01-10 | 1993-12-14 | Rochester Medical Corporation | Microcidal agent releasing catheter with balloon |
US5324260A (en) * | 1992-04-27 | 1994-06-28 | Minnesota Mining And Manufacturing Company | Retrograde coronary sinus catheter |
US5352215A (en) * | 1992-08-26 | 1994-10-04 | Scimed Life Systems, Inc. | Y-adapter with a sideport radius |
US5389091A (en) * | 1991-03-07 | 1995-02-14 | C. R. Bard, Inc. | Site-selective durability-enhanced catheter and methods of manufacturing and using same |
US5486208A (en) * | 1993-02-10 | 1996-01-23 | Ginsburg; Robert | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification |
US5501669A (en) * | 1990-01-10 | 1996-03-26 | Rochester Medical Corporation | Urinary catheter with reservoir shroud |
US5558644A (en) * | 1991-07-16 | 1996-09-24 | Heartport, Inc. | Retrograde delivery catheter and method for inducing cardioplegic arrest |
US5593718A (en) * | 1990-01-10 | 1997-01-14 | Rochester Medical Corporation | Method of making catheter |
US5755687A (en) * | 1997-04-01 | 1998-05-26 | Heartport, Inc. | Methods and devices for occluding a patient's ascending aorta |
US5762996A (en) * | 1996-04-15 | 1998-06-09 | Lucas; Daniel R. | Silicone balloon catheter |
US5765568A (en) * | 1994-05-27 | 1998-06-16 | Heartport, Inc. | Catheter system and method for venting the left ventricle |
US5769812A (en) * | 1991-07-16 | 1998-06-23 | Heartport, Inc. | System for cardiac procedures |
US5792094A (en) * | 1991-07-16 | 1998-08-11 | Heartport, Inc. | Method of delivering cardioplegic fluid to a patient's heart |
US5837003A (en) * | 1993-02-10 | 1998-11-17 | Radiant Medical, Inc. | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modification |
US5971954A (en) * | 1990-01-10 | 1999-10-26 | Rochester Medical Corporation | Method of making catheter |
US6033383A (en) * | 1996-12-19 | 2000-03-07 | Ginsburg; Robert | Temperature regulating catheter and methods |
US6096068A (en) * | 1998-01-23 | 2000-08-01 | Innercool Therapies, Inc. | Selective organ cooling catheter and method of using the same |
US6110168A (en) * | 1993-02-10 | 2000-08-29 | Radiant Medical, Inc. | Method and apparatus for controlling a patient's body temperature by in situ blood temperature modifications |
US6129737A (en) * | 1994-03-01 | 2000-10-10 | Boston Scientific Corporation | Asymmetric dilatation balloon |
US6149677A (en) * | 1998-03-31 | 2000-11-21 | Innercool Therapies, Inc. | Circulating fluid hypothermia method |
US6159178A (en) * | 1998-01-23 | 2000-12-12 | Heartport, Inc. | Methods and devices for occluding the ascending aorta and maintaining circulation of oxygenated blood in the patient when the patient's heart is arrested |
US6165207A (en) * | 1999-05-27 | 2000-12-26 | Alsius Corporation | Method of selectively shaping hollow fibers of heat exchange catheter |
US6224624B1 (en) | 1998-03-24 | 2001-05-01 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method |
US6235048B1 (en) | 1998-01-23 | 2001-05-22 | Innercool Therapies, Inc. | Selective organ hypothermia method and apparatus |
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US6251129B1 (en) | 1998-03-24 | 2001-06-26 | Innercool Therapies, Inc. | Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control |
US6251130B1 (en) | 1998-03-24 | 2001-06-26 | Innercool Therapies, Inc. | Device for applications of selective organ cooling |
US6254626B1 (en) | 1998-03-24 | 2001-07-03 | Innercool Therapies, Inc. | Articulation device for selective organ cooling apparatus |
US6261312B1 (en) | 1998-06-23 | 2001-07-17 | Innercool Therapies, Inc. | Inflatable catheter for selective organ heating and cooling and method of using the same |
US6287326B1 (en) | 1999-08-02 | 2001-09-11 | Alsius Corporation | Catheter with coiled multi-lumen heat transfer extension |
US6299599B1 (en) | 1999-02-19 | 2001-10-09 | Alsius Corporation | Dual balloon central venous line catheter temperature control system |
US6312452B1 (en) | 1998-01-23 | 2001-11-06 | Innercool Therapies, Inc. | Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device |
US6325818B1 (en) | 1999-10-07 | 2001-12-04 | Innercool Therapies, Inc. | Inflatable cooling apparatus for selective organ hypothermia |
US6368304B1 (en) | 1999-02-19 | 2002-04-09 | Alsius Corporation | Central venous catheter with heat exchange membrane |
US6379378B1 (en) | 2000-03-03 | 2002-04-30 | Innercool Therapies, Inc. | Lumen design for catheter |
US6383434B2 (en) | 1990-01-10 | 2002-05-07 | Rochester Medical Corporation | Method of shaping structures with an overcoat layer including female urinary catheter |
US6393320B2 (en) | 1999-02-19 | 2002-05-21 | Alsius Corporation | Method for treating cardiac arrest |
US6419643B1 (en) | 1998-04-21 | 2002-07-16 | Alsius Corporation | Central venous catheter with heat exchange properties |
US6440158B1 (en) | 1990-05-11 | 2002-08-27 | Mark A. Saab | Heat transfer catheter apparatus and method of making and using same |
US6447474B1 (en) | 1999-09-15 | 2002-09-10 | Alsius Corporation | Automatic fever abatement system |
US6450990B1 (en) | 1998-08-13 | 2002-09-17 | Alsius Corporation | Catheter with multiple heating/cooling fibers employing fiber spreading features |
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US6464716B1 (en) | 1998-01-23 | 2002-10-15 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method |
US6471717B1 (en) | 1998-03-24 | 2002-10-29 | Innercool Therapies, Inc. | Selective organ cooling apparatus and method |
US6482171B1 (en) | 1991-07-16 | 2002-11-19 | Heartport, Inc. | Multi-lumen catheter |
US6491039B1 (en) | 1998-01-23 | 2002-12-10 | Innercool Therapies, Inc. | Medical procedure |
US6491716B2 (en) | 1998-03-24 | 2002-12-10 | Innercool Therapies, Inc. | Method and device for applications of selective organ cooling |
US6497721B2 (en) | 1993-02-10 | 2002-12-24 | Radiant Medical, Inc. | Method and apparatus for regional and whole body temperature modification |
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US20030078641A1 (en) * | 1998-01-23 | 2003-04-24 | Innercool Therapies, Inc. | Selective organ hypothermia method and apparatus |
US6572640B1 (en) | 2001-11-21 | 2003-06-03 | Alsius Corporation | Method and apparatus for cardiopulmonary bypass patient temperature control |
US6576002B2 (en) | 1998-03-24 | 2003-06-10 | Innercool Therapies, Inc. | Isolated selective organ cooling method and apparatus |
US6582398B1 (en) | 1999-02-19 | 2003-06-24 | Alsius Corporation | Method of managing patient temperature with a heat exchange catheter |
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