Búsqueda Imágenes Maps Play YouTube Noticias Gmail Drive Más »
Iniciar sesión
Usuarios de lectores de pantalla: deben hacer clic en este enlace para utilizar el modo de accesibilidad. Este modo tiene las mismas funciones esenciales pero funciona mejor con el lector.


  1. Búsqueda avanzada de patentes
Número de publicaciónUS2525381 A
Tipo de publicaciónConcesión
Fecha de publicación10 Oct 1950
Fecha de presentación25 Sep 1947
Fecha de prioridad25 Sep 1947
Número de publicaciónUS 2525381 A, US 2525381A, US-A-2525381, US2525381 A, US2525381A
InventoresTower Paul
Cesionario originalTower Paul
Exportar citaBiBTeX, EndNote, RefMan
Enlaces externos: USPTO, Cesión de USPTO, Espacenet
Contact-type electrode holder
US 2525381 A
Resumen  disponible en
Previous page
Next page
Reclamaciones  disponible en
Descripción  (El texto procesado por OCR puede contener errores)

Oct. 10, 1950 I P. TOWER 2,525,331

cormc'r TYPE ELECTRODE .noppsa Filed Sept. 25, 1947 Fig.

Inventor v Paul Tower By Attorneys Patented Oct. 10,1950

UNITED ,r STATES PATENT OFFICE f V f 2,525,381 l contract-Tyre ELECTRODE HO DER 7 ram 'rew'er, Los Angelcs, Calif. Applicants s'icemta 25, 1947,- Serial No; 776,004

The present invention relates re ways and means whereby an acceptable and usable eye treatment technique known as iontophore'sis (ion ization and/or ionic medication) is followed in dispersing and applying penicillin'or other medicaments directly to' the cornea of the eye.

To those skilled in the art to which the invenof medication in the tissues of the human eye is achieved when the stated method or technique" (iontophoresis) is used. I

What is more, it is generally recognized that there are many eye electrodes, such as used in the stated technique or method, in use, these ranging from a piece of cotton wool soaked in solution and placed betweena small metal plate and the eye, to an electrode consisting of a" small cylindrical glass tube fitting over the cornea. Some technicians and doctors and workers use a plain probe rod such as for example Hamburgers electrode which, generally speaking comprises a thin carbon red, the end of which is wrapped in cotton which has been soaked in an appropriate fluid.

Manifestly, all of these electrodes are hard to handle and manipulate and require careful manipulation and, even so, are apt to cause injury to the delicate epithelium of the cornea. Since the electrodes are not mechanically or otherwise sustained in place, they must be held in position, by hand, at all times. The usual procedure requires the presence of an assistant to handle the electrical apparatus, and the doctor whose job it is to hold the electrode in its proper position in relation to the cornea during the accomplishment of the medication technique.

An object of the present invention is to provide an electrode holder in the form of a contact lens which fits into the human eye in contact with the eyeball and which is so constructed that when once installed, it remains in place as Repeated experimentacontact lens, stays in direct contact with the eyeball and therefore moves with the eye, thus obviating'the likelihood that the electrical circuit will be broken when on. V

The principal object is to provide a simple and practical electrode holder in the form of an adaptor carried by a contact-type lens which sufficiently holds the electrodethat the assistant may be dispensed with and 'a doctor mayoperate an appropriate and reliable holder for an 'electhe electrical apparatus.

7 Another object of the invention is to providea contact-type holder which is made of plastic to act as an insulator and to minimize likelihood of breakage'and to also provide a lightweight struc' ture free from pressure and irritational tendencies.

Other objects and advantages will become more readily apparent from the following description and the accompanying illustrative drawings.

In the drawings, wherein like numerals are employed to designate like parts throughout the views:

Figure 1 is a sectional view of an electrode I holder constructed in accordance 'with the princip'lesof the invention and showing the manner in which the same, in practice, is used;

Figure 2 is a front elevationalvi'ew of whatis seen from left to right in Figure 1;

Figure 3 is a central vertical sectional viewthrough the device removed from the eye; and 1*"i'gure 4 is an enlarged fragmentary sectional View to bring out certain other details.

The electrode holder is a unitary appliance,

as denoted by the numberal 6 and is primarily made up of plastic or an aquivalent light weight, durable insulating material. It is characterized primarily by a substantially semi-spherical cup 1 which resembles an ordinary contact lens and which is suitably concavo-convex in form to fit into the human eye A in proper relation to the cornea B of the eyeball C, as shown for example in Figure 1. The crown portion which may be said to be the corneal part of the cup is formed with a concavo-convex boss 8 and this forms a shallow cavity or receptacle 9 for the medicament (penicillin or whatever is to be used for cornea treatment), The receptacle forming boss 9 is provided with a centrally situated aperture permitting access to the cornea and this in turn is formed with an outstanding sleeve-like extension I!) which constitutes an adaptor socket for the silver electrode H. The electrode has a shank portion fitting in the adapter sleeve and has its inner end provided with a concaved head I2 forming an assembling flange. The other end.

. 4 convex boss forming a medicament receptacle, and the crown portion of said boss having an outstanding tubular extension, said extension being adapted to serve as a holding socket for an electrode, an electrode situated in said socket, said electrode having an eye at its outer end to accommodate a current supply wire, and having a headed portion on its inner end projecting into said boss to contact the medicament to be held cornea. In rare extreme cases like in keratoconus, a lens with a 6.5 mm. corneal curve can be used or in very high myopias a 8.0 mm. corneal curve is used. In use the cup I is inserted under the patients lids in the usual way used in insert-- ing ordinary contact lenses. The extension serves not only to hold the metal electrode in place, but acts as an insulator. Otherwise, the patients lid would strike against the metal when the current is on, giving not only electric shocks to the patient, but causing the intensity of the current to fluctuate. The electrode is made from silver. It is slightly countersunk on the inner surface of the corneal portion, so as to present an even surface and projects through the sleeve, ending in a small eye. vanic, machine (not shown) is inserted and looped through this ring making a simple and sufficient connection. Thus the current travels through the electrode and is conveyed into the medication contained in the corneal portion. This solution being in contact with the cornea, ionization (or iontophoresis) takes place and the medication is thus enabled to enter the cornea and tissues of the eye according to the established principles underlying ionization treatment.

A careful consideration of the foregoing description in conjunction with the invention as illustrated in the drawings will enable the reader to obtain a clear understanding and impression of the alleged features of merit and novelty sufficient to clarify the construction of the invention as hereinafter claimed.

Minor changes in shape, size, materials and rearrangement of parts may be resorted to in actual practice so long as no departure is made from the invention as claimed.

I claim:

' 1. An eye appliance for use in connection with ionic medication technique comprising a substantially semi-spherical plastic contact cup adapted to be suction fitted in direct contact with an eyeball, the axial portion of said cup being provided with an outstanding concavo- The wire from the gal-,

in the latter.

2. An eye appliance for use by an eye doctor during an ionic medication treatment of a patients eye, said appliance being self-sustained when it is once inserted into the patients eye and obviating holding of same either by the doctor or an assistant comprising a concavo-convex medicament holding applicator having a marginally surrounding concavo-convex flange adapted to rest directly against the eyeball of the patient and to be held partly by suction and to reside beneath the eyelids and to be partly held in place by said eyelids, and an electrode carried by said applicator, said electrode being spaced clear of the cornea of the eye when in use and adapted to contact the medicament in said applicator.

3. An eye appliance for use by an eye doctor employing ionic medication techniques compris ing arelatively small concavo-convex medicament containing receptacle having a central aperture and an outstanding tubular extension constituting an electrode receiving and holding socket, and means for holding said receptacle in spaced opposed relation to the cornea of the eye, said means being an annular flange attached marginally to the receptacle and shaped to fit in direct contact with the eyeball of the user and being sufficiently thin to fit beneath the eyelids of the user whereby to utilize the eyelids and suction to hold said flange in place and consequently to position and hold said medicament receptacle in place, and an electrode fitted in said socket and having a headed inner end anchored in the receptacle and its outer end located for connection thereto of a current delivering wire.


REFERENCES CITED The following references are of record in the file of this patent:


Citas de patentes
Patente citada Fecha de presentación Fecha de publicación Solicitante Título
US768721 *4 Abr 190430 Ago 1904William Benedict BassellElectrode for therapeutical purposes.
Citada por
Patente citante Fecha de presentación Fecha de publicación Solicitante Título
US3122137 *30 Oct 196125 Feb 1964Gustav ErlangerDevice for facilitating iontophoresis treatment of eyes
US3485244 *15 Dic 196623 Dic 1969Hyman RosenEye applicator
US3670736 *17 Jul 197020 Jun 1972Health Systems IncTherapeutic instrumentation electrode
US4109648 *15 Dic 197629 Ago 1978National Research Development CorporationElectrode assemblies
US4271841 *31 Ene 19809 Jun 1981Medtronic, Inc.Electro-ocular stimulation system
US4326529 *5 Dic 197927 Abr 1982The United States Of America As Represented By The United States Department Of EnergyCorneal-shaping electrode
US4564016 *13 Ago 198414 Ene 1986The Board Of Trustees Of The Leland Stanford Junior UniversityApparatus for introducing ionized drugs into the posterior segment of the eye and method
US4603697 *7 Ene 19855 Ago 1986William KamerlingSystem for preventing or treating open angle glaucoma and presbyopia
US4881543 *28 Jun 198821 Nov 1989Massachusetts Institute Of TechnologyCombined microwave heating and surface cooling of the cornea
US4955378 *17 Ene 198911 Sep 1990University Of South FloridaApparatus and methods for performing electrofusion at specific anatomical sites
US6001088 *4 Dic 199514 Dic 1999The University Of QueenslandIontophoresis method and apparatus
US6101411 *24 Sep 19988 Ago 2000Newsome; David A.Dilation enhancer
US6154671 *4 Ene 199928 Nov 2000OptisinvestDevice for the intraocular transfer of active products by iontophoresis
US6319240 *25 May 199920 Nov 2001Iomed, Inc.Methods and apparatus for ocular iontophoresis
US65392513 Ago 200125 Mar 2003Iomed, Inc.Ocular iontophoretic apparatus
US654628318 Oct 20008 Abr 2003Iomed, Inc.High current density iontophoretic device and method of use thereof
US672857322 Jun 200027 Abr 2004Iomed, Inc.Ocular iontophoretic apparatus handle
US71519608 Ago 200019 Dic 2006Newsome David ADilation enhancer with pre-mediated contact lenses
US71924298 Dic 200320 Mar 2007The Trustees Of Dartmouth CollegeThermokeratoplasty systems
US72526553 Ago 20017 Ago 2007Iomed, Inc.Ocular iontophoretic apparatus handle
US73779179 Dic 200227 May 2008The Trustees Of Dartmouth CollegeFeedback control of thermokeratoplasty treatments
US771326819 Mar 200711 May 2010The Trustees Of Dartmouth CollegeThermokeratoplasty systems
US79810629 Oct 200919 Jul 2011Imi Intelligent Medical Implants AgMechanically activated objects for treatment of degenerative retinal disease
US80991629 Dic 200517 Ene 2012Eyegate Pharma, S.A.S.Ocular iontophoresis device
US834893631 Oct 20078 Ene 2013The Trustees Of Dartmouth CollegeThermal treatment systems with acoustic monitoring, and associated methods
US845239115 Dic 201128 May 2013Eyegate Pharma S.A.S.Ocular iontophoresis device
US8480638 *4 Oct 20079 Jul 2013Aciont, Inc.Intraocular iontophoretic device and associated methods
US892396113 May 201130 Dic 2014The Cleveland Clinic FoundationElectrode assembly for delivering a therapeutic agent into ocular tissue
US913198426 Feb 201015 Sep 2015The Trustees Of Dartmouth CollegeThermokeratoplasty systems
US923813121 May 201319 Ene 2016Eyegate Pharma S.A.S.Ocular iontophoresis device
US9764150 *22 Oct 201519 Sep 2017Oculeve, Inc.Contact lens for increasing tear production
US20020022794 *3 Ago 200121 Feb 2002Beck Jon E.Ocular iontophoretic apparatus handle
US20040111086 *9 Dic 200210 Jun 2004Trembly B. StuartFeedback control of thermokeratoplasty treatments
US20040143250 *8 Dic 200322 Jul 2004Trembly B. StuartThermokeratoplasty systems
US20050004625 *9 Jun 20046 Ene 2005Chow Alan Y.Treatment of degenerative retinal disease via electrical stimulation of surface structures
US20050033202 *12 Abr 200410 Feb 2005Chow Alan Y.Mechanically activated objects for treatment of degenerative retinal disease
US20060142818 *12 Dic 200529 Jun 2006OptobionicsMethods for improving damaged retinal cell function
US20070123814 *9 Dic 200531 May 2007Eyegate PharmasaOcular iontophoresis device
US20070161976 *19 Mar 200712 Jul 2007Trembly B SThermokeratoplasty systems
US20070299386 *4 Ago 200627 Dic 2007Minu, L.L.C.Delivery of an ocular agent using iontophoresis
US20080114428 *31 Oct 200715 May 2008The Trustees Of DartmouthThermal Treatment Systems With Acoustic Monitoring, And Associated Methods
US20090093780 *4 Oct 20079 Abr 2009Tuitupou Anthony LIntraocular iontophoretic device and associated methods
US20100121231 *9 Oct 200913 May 2010Chow Alan YMechanically activated objects for treatment of degenerative retinal disease
US20100160907 *26 Feb 201024 Jun 2010Trembly B StuartThermokeratoplasty Systems
US20110077582 *13 Oct 201031 Mar 2011Tuitupou Anthony LIntraocular iontophoretic device and associated methods
US20160114172 *22 Oct 201528 Abr 2016Oculeve, Inc.Contact lens for increasing tear production
EP1452203A2 *17 Dic 19981 Sep 2004Optis FranceOcular iontophoresis device for transferring a plurality of active ingredients
EP1452203A3 *17 Dic 19988 Sep 2004Optis FranceOcular iontophoresis device for transferring a plurality of active ingredients
WO2007099406A2 *29 Nov 20067 Sep 2007Eyegate Pharma S.A.Ocular iontophoresis device
WO2007099406A3 *29 Nov 200623 Oct 2008Eyegate Pharma S AOcular iontophoresis device
Clasificación de EE.UU.604/20, 607/141, 351/159.2
Clasificación internacionalA61N1/04, A61F9/00, A61N1/30
Clasificación cooperativaA61F9/0017, A61N1/30, A61N1/044
Clasificación europeaA61N1/04E1I1S, A61F9/00B2, A61N1/30