|Número de publicación||US3310051 A|
|Tipo de publicación||Concesión|
|Fecha de publicación||21 Mar 1967|
|Fecha de presentación||10 Dic 1963|
|Fecha de prioridad||10 Dic 1963|
|Número de publicación||US 3310051 A, US 3310051A, US-A-3310051, US3310051 A, US3310051A|
|Inventores||Schulte Rudolf R|
|Cesionario original||Schulte Rudolf R|
|Exportar cita||BiBTeX, EndNote, RefMan|
|Citas de patentes (6), Citada por (126), Clasificaciones (6), Eventos legales (1)|
|Enlaces externos: USPTO, Cesión de USPTO, Espacenet|
arch 21, 1967 R. R. SCHULTE 3,31%051 SURGICAL RESERVOIR FOR IMPLANTATION BENEATH THE SKIN Filed Dec. 10, 1963 SCALP-// rfmaw United States Patent 3,310,051 SURGICAL RESERVGIR FOR Iii PLANTATION BENEATH THE SKIN Rudolf R. Schulte, 3328 Calle Fresno, Santa Barbara, Calif. 93185 Filed Dec. 10, 1963, Ser. No. 329,443 2 Claims. (Cl. 128-216) This invention relates to a surgical implant which provides a reservoir located conveniently to the skin of a person which may be utilized to introduce, withdraw, or mix fluids in regions located farther inside the body.
There are numerous instances Where repetitive samplings of body fluids need to be made, or in which repetitive introductions or medication must be made to interior regions. An example i the repetitive sampling of cerebro-spinal fluid, and vthe introduction of medication thereto, such as in the treatment of cryptococcal meningitis or tubercular meningitis. Medication for these diseases is often only marginally effective if given intravenously, because in order to supply the concentration needed at the situs of the ailment, the total dosage in the body would have to be too high. In fact, these diseases have been unmanageable with intravenous injections principally for this reason. However, if the medications are injected at the situs of the ailment, the local concentration can be made high enough to be effective, and the diseases may be controlled, even though the total dosage in the body is relatively low.
A concurrent problem associated with the foregoing is that concentration levels need to be maintained at the situs over a protracted period of time. To make repeated injections by means of repetitive punctures is obviously undesirable, and in many regions of the body soon becomes impossible. One reason is that fibrosis develops around t-he multiple needle tracks and renders access increasingly diflicult, particularly in the brain. Furthermore, repeated punctures of the brain are inherently undesirable. While the examples given in this specification relate to treatment of regions within the skull, clearly the same criteria apply to ailments in other regions of the body.
It is an object of this invention to provide a device which, once installed, gives continuous access to internal regions of the body without requiring additional needle penetrations into these regions. Instead, a tubular portion of the device remains in the body and extends to the affected area where it serves as a continuously-available conduit placed there but once. Thereafter, a syringe or other device need only be placed in fluid communication with this conduit to inject, Withdraw or mix fluids in the interior region.
Still another object of the invention is to provide a mixing or flushing reservoir into which fluids may readily be injected or from which they may readily be withdrawn. An optional object is to provide such a reservoir which may also serve to provide surge-generatiug means of flush and mix fluids in it and in the region under treatment.
A device according to this invention comprises a tube having a central passage, the tube being adapted to be inserted in to the body so that its passage communicates with a selected region therein. A capsule is adapted to be connected to this tube and to be placed beneath the skin of the body. This capsule comprises an enclosure which has an internal periphery and a first and second wall, these walls facing each other inside the capsule. The wall next to the skin is tolerant to, and self-sealing after, needle puncture. One of the walls has a passage therethrough in fluid communication with the passage through the tube.
According to a preferred but optional feature of the invention, one of the walls is flexible and palpable through the skin by force exerted by the hand. The material of the flexible wall is flexible enough to be moved toward the other wall and thereby reduce the volume of the capsule and also sufficiently springy to return to its normal unstressed condition, thereby providing for pumping means to create bi-directional flow in the passages for mixing purposes.
The above and other features of this invention will be fully understood from the following detailed description and the accompanying drawings in which:
FIG. 1 is a cross-section of a portion of a skull, showing the device of the invention, partly in cutaway crosssection and in its normal, unstressed condition;
FIG. 2 is a top view of the invention, partly in cutaway cross-section;
FIG. 3 is a bottom view of the device taken at line 33 of FIG. 1; and
FIG. 4 is a fragmentary cross-section of a portion of FIG. 1, showing the device in another of its conditions.
FIG. 1 illustrates a skull 10, showing the scalp 11 and the bone 12 of the skull surrounding the brain 13. The drawing of the anotomical portions is simplified because these form no portion of the present invention. It will be noted that the device is installed within a burr hole 14 having an internal wall 15 in the bone of the skull, and is held beneath the skin of the scalp by means of a sutured slit 16.
The reservoir elements 20 comprising the invention includes a tube 21 having a central passage 22 and a closed end 23. Perforations 24 through the wall provide for fluid communication between the passage and the outside of the tube. The tube is connected to a capsule 25 by means of a connector 26, which connector is attached to a passage extension 27 which has a passage 28 that enters the capsule itself through one wall thereof. The capsule has a boss 29 which fits within burr hole 14 and provides for lateral restraint of the device. The capsule outward of the boss rests on the skull so as to give longitudinal restraint.
The capsule is a continuou enclosure and includes a circumferential periphery defined by circumferential edge 30. First and second interior walls 31, 32 are provided on opposite sides of the periphery. The first wall lies closer to the skull, and includes an interior crown 33 which surrounds the opening 34 of passage 28 into the interior of the capsule. The crown has a plurality of notches 35 formed therein.
Second wall 32 is generally domed and has a central section which is thicker than the edges. This wall is flexible and, as best shown in FIG. 4, is adapted to be palpated by finger pressure through the scalp to move it toward the first wall, thereby reducing the volume of the capsule. In order to prevent the first and second walls from adhering to each other and closing the passages, the crown is provided to hold them apart. However, the notches provide for fluid flow past the crown to the passage even when the second wall is pressed against the crown.
The entire structure is, of course, made of material which is compatible with the human tissue with which it comes in contact. A convenient substance is silicone rubber manufactured by Dow Corning Company, of Midland, Mich. The thickness of the second wall is selected such that it is springy enough to restore itself to its normal, unstressed condition shown in FIG. 1, and yet sufliciently flexible that it can be deflected to the configuration shown in FIG. 4. It is also tolerant to repetitive needle punctures (with a resonable number), because, as best shown in FIG. 1, material may be in- 3 jected from a hypodermic syringe 36 by puncturing the scalp and the second wall with the needle. When the needle is withdrawn, the material of the second wall will seal the opening made by the needle.
The use of the device should be evident from the foregoing. If it is desired either to withdraw fluid from region 37 within the brain or to introduce medication thereto, the tube will be forced into this region by means well known in the surgical arts. Once in place, this tube is connected to the capsule, and the capsule is placed in position as shown, and the scalp sutured over the capsule. The capsule is filled with fluid, which, after a time, will be identical with fluid in the region under study, particularly if the device is pumped for a while, either by depressing the second wall or by pumping with a syringe. The fluid may be withdrawn for sampling by a hypodermic syringe. Also, medication may be introduced to the region by a syringe as shown, mixing being attained either by depressing the second wall or by pumping with the syringe.
It will thereby be seen that this device provides a reservoir of fluid which in effect is an extension of a region under treatment or study. Only one puncture of the brain or other region is necessary because the tube remains in place for sensible periods of time to provide a continuously-available conduit to the region, and the dome i available for introduction and withdrawal of material even were the second wall to be too stifl to flex. On the other hand, should the device be made flexible enough for this purpose, then even better results may be attained as a result of the more complete bi-directional flow attainable thereby.
This invention is not to be limited by the embodiment shown in the drawings and described in the description which is given by way of example and not of limitation, but only in accordance with the scope of the appended claims.
1. A reservoir element for implantation in a human being comprising: a tube having a central passage and adapted to be inserted into the body so that its passage communicates with a selected region to be treated; and
a capsule of a size to be placed beneath the skin so as to rest between the skin and the bony structure of the body, said capsule comprising an envelope having an in ner cavity bounded by a first and a second wall, the first wall being adapted to lay on surface to surface contact with said bony structure, the second wall being domed and springily flexible so as to be deformable and movable toward the first wall so as to reduce the volume of the cavity as the result of external force thereon, and to return to its dome shape of its own accord when the force is removed, there being a passage through said first wall connected to the passage in the tube, and a crown formed inside the cavity around the entrance of the passage thereinto, said cr-own having notches thereon, whereby the walls are prevented from adhering to each other and also from shutting off flow through the passage when the capsule is compressed, the second wall being made of material which permits puncture by a needle and is self-sealing after the needle is withdrawn.
2. A reservoir element according to claim 1 in which a boss surrounds the capsule passage on the outside surface of the first wall, whereby to fit in a hole in the said bony structure and thereby to provide lateral positioning support for the capsule.
References Cited by the Examiner UNITED STATES PATENTS 513,238 1/1894 Lalonde 128-126 3,021,842 2/1962 Flood 128215 3,111,125 11/1963 Schulte 128350 3,144,866 8/1964 Ellis 128232 3,154,074 10/1964 Harrison l28232 FOREIGN PATENTS 790,220 2/ 1958 Great Britain.
OTHER REFERENCES Lancet, vol 2 (63), No. 7315, Nov. 9, 1963, pp. 983-84.
RICHARD A. GAUDET, Primary Examiner.
DALTON L, TRULUCK, Examiner.
|Patente citada||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US513238 *||23 Feb 1893||23 Ene 1894||Joseph lalonde|
|US3021842 *||5 Nov 1958||20 Feb 1962||John F Flood||Hypodermic needle guide|
|US3111125 *||6 Nov 1961||19 Nov 1963||Schulte Rudolf R||Drainage device|
|US3144866 *||11 Ago 1961||18 Ago 1964||Briggs Castling & Kelly||Disposable douche syringe and bag|
|US3154074 *||23 Oct 1962||27 Oct 1964||Lehn & Fink Products Corp||Internal medicament applicator|
|GB790220A *||Título no disponible|
|Patente citante||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US3530492 *||5 Dic 1967||22 Sep 1970||Ferber Jack R||Method and apparatus for administering hypodermic injections|
|US3613663 *||9 Sep 1968||19 Oct 1971||Johnson Roger P||Apparatus to provide communication with the veins of a patient|
|US3640269 *||24 Oct 1969||8 Feb 1972||Delgado Jose M R||Fluid-conducting instrument insertable in living organisms|
|US3731681 *||14 Ene 1972||8 May 1973||Univ Minnesota||Implantable indusion pump|
|US3765414 *||10 Mar 1972||16 Oct 1973||Hydro Med Sciences Inc||Drug release system|
|US3783868 *||6 May 1971||8 Ene 1974||Gulf Oil Corp||Percutaneous implant|
|US3796217 *||17 May 1973||12 Mar 1974||Hydr Med Sciences Inc||Drug release system|
|US3831583 *||5 Feb 1973||27 Ago 1974||Univ Calif||Implantable bulb for inflation of surgical implements|
|US3864874 *||29 Ene 1973||11 Feb 1975||Carroll Raymond L||Method and apparatus for introducing a fluid into the vascular system of a tree or similar plant|
|US3958562 *||2 Dic 1974||25 May 1976||Hakim Company Limited||Implantable pressure sensor|
|US3971376 *||2 Oct 1974||27 Jul 1976||Ceskoslovenska Akademie Ved||Method and apparatus for introducing fluids into the body|
|US3998222 *||15 May 1975||21 Dic 1976||Shihata Alfred A||Subcutaneous arterio-venous shunt with valve|
|US4013074 *||6 Abr 1976||22 Mar 1977||Siposs George G||Implantable medication-dispensing device|
|US4026287 *||10 Dic 1975||31 May 1977||Irene Haller||Syringe with retractable cannula|
|US4160454 *||14 Feb 1977||10 Jul 1979||University Of Utah||Implantable catheter system|
|US4184497 *||26 Ago 1977||22 Ene 1980||University Of Utah||Peritoneal dialysis catheter|
|US4190057 *||27 Dic 1977||26 Feb 1980||Thoratec Laboratories Corporation||Device for determining the patentcy of a blood vessel|
|US4253201 *||24 May 1979||3 Mar 1981||Ross David A||Prosthesis with self-sealing valve|
|US4317452 *||4 Feb 1980||2 Mar 1982||C. R. Bard, Inc.||Body fluid drain|
|US4405305 *||17 Feb 1981||20 Sep 1983||University Of Utah Research Foundation||Subcutaneous peritoneal injection catheter|
|US4464178 *||25 Nov 1981||7 Ago 1984||Dalton Michael J||Method and apparatus for administration of fluids|
|US4557724 *||12 Ago 1983||10 Dic 1985||University Of Utah Research Foundation||Apparatus and methods for minimizing cellular adhesion on peritoneal injection catheters|
|US4559033 *||12 Ago 1983||17 Dic 1985||University Of Utah Research Foundation||Apparatus and methods for minimizing peritoneal injection catheter obstruction|
|US4569675 *||12 Sep 1983||11 Feb 1986||Infusaid Corporation||Transcutaneous infusion system|
|US4585010 *||2 Jul 1984||29 Abr 1986||Enrico Ascer||Process and apparatus for measurement of outflow resistance|
|US4634424 *||23 Abr 1984||6 Ene 1987||Windsor Medical, Inc.||Multiple re-entry implantable septum and method of using same|
|US4673394 *||17 Ene 1986||16 Jun 1987||Strato Medical Corporation||Implantable treatment reservoir|
|US4687001 *||14 Feb 1977||18 Ago 1987||The United States Of America As Represented By The Department Of Health And Human Services||Subcutaneous fluid and culture chamber and implant technique|
|US4710167 *||21 May 1986||1 Dic 1987||Applied Precision Limited||Implantable device for chronically injecting a substance, in particular a therapeutant|
|US4710174 *||16 Dic 1985||1 Dic 1987||Surgical Engineering Associates, Inc.||Implantable infusion port|
|US4710177 *||15 May 1986||1 Dic 1987||Smith Robert R||Subcutaneous ventricular injection apparatus and method|
|US4767410 *||19 Jun 1987||30 Ago 1988||Surgical Engineering Associates, Inc.||Implantable infusion port|
|US4772261 *||29 Ene 1987||20 Sep 1988||Board Of Regents, The University Of Texas System||Intramedullary catheter|
|US4772270 *||18 Jun 1987||20 Sep 1988||Catheter Technology Corp.||Inseparable port/catheter tube assembly and methods|
|US4772276 *||27 Jul 1987||20 Sep 1988||Catheter Technology Corp.||Catheter tube coupling assembly and methods|
|US4781695 *||11 Jul 1986||1 Nov 1988||Dalton Michael J||Implantable fluid dispenser|
|US4857053 *||29 Ago 1988||15 Ago 1989||Dalton Michael J||Matrix septum|
|US4904241 *||21 Oct 1988||27 Feb 1990||Medical Engineering Corp.||Septum with a needle stop at the fluid transfer port|
|US4915690 *||2 Feb 1988||10 Abr 1990||C. R. Bard, Inc.||Micro-injection port|
|US4969870 *||7 Jun 1989||13 Nov 1990||The Regents Of The University Of California||Method and apparatus for intraosseous infusions|
|US5041098 *||19 May 1989||20 Ago 1991||Strato Medical Corporation||Vascular access system for extracorporeal treatment of blood|
|US5092849 *||24 Ene 1990||3 Mar 1992||Shiley Infusaid, Inc.||Implantable device|
|US5122114 *||1 Feb 1991||16 Jun 1992||Board Of Regents, University Of Texas System||Method of using intramedullary catheter|
|US5312364 *||6 Ago 1993||17 May 1994||Pyng||Intraosseous infusion device|
|US5332398 *||10 Abr 1992||26 Jul 1994||Board Of Regents, The University Of Texas System||Intramedullary catheter|
|US5399168 *||29 Jul 1992||21 Mar 1995||C. R. Bard, Inc.||Implantable plural fluid cavity port|
|US5702414 *||5 Sep 1996||30 Dic 1997||Optonol Ltd||Method of implanting an intraocular implant|
|US5713858 *||28 Abr 1995||3 Feb 1998||Medtronic, Inc.||Permanently implantable guiding catheter|
|US5792104 *||10 Dic 1996||11 Ago 1998||Medtronic, Inc.||Dual-reservoir vascular access port|
|US5817052 *||26 Dic 1995||6 Oct 1998||Pyng Medical Corp.||Apparatus for intraosseous infusion or aspiration|
|US5836935 *||28 Ene 1997||17 Nov 1998||Ashton; Paul||Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body|
|US5848989 *||5 Jun 1997||15 Dic 1998||Davinci Biomedical Research Products, Inc.||Implantable port with low profile housing for delivery/collection of fluids and implantation method|
|US5968058 *||14 Jul 1997||19 Oct 1999||Optonol Ltd.||Device for and method of implanting an intraocular implant|
|US6036721 *||17 May 1999||14 Mar 2000||Cap Incorporated||Puncture closure|
|US6203513||20 Nov 1997||20 Mar 2001||Optonol Ltd.||Flow regulating implant, method of manufacture, and delivery device|
|US6228088||20 Sep 1995||8 May 2001||Board Of Regents, The University Of Texas System||Combination drill bit and intrametullary catheter and method of using same|
|US6468283||26 Ago 1999||22 Oct 2002||Optonol, Ltd.||Method of regulating pressure with an intraocular implant|
|US6478783||26 May 2000||12 Nov 2002||H. Robert Moorehead||Anti-sludge medication ports and related methods|
|US6510600||4 Dic 2000||28 Ene 2003||Optonol, Ltd.||Method for manufacturing a flow regulating implant|
|US6558342||2 Jun 1999||6 May 2003||Optonol Ltd.||Flow control device, introducer and method of implanting|
|US6623462||17 Abr 2002||23 Sep 2003||Harmac Medical Products, Inc.||Needle safety guard|
|US6726664||6 Ago 2001||27 Abr 2004||Optonol Ltd.||Flow control device, introducer and method of implanting|
|US6726678 *||22 Feb 2001||27 Abr 2004||Isurgical, Llc||Implantable reservoir and system for delivery of a therapeutic agent|
|US6736797||19 Jun 1998||18 May 2004||Unomedical A/S||Subcutaneous infusion set|
|US6824530||18 Abr 2002||30 Nov 2004||Harmac Medical Products, Inc.||Combination needle assembly and needle safety guard|
|US7063691||16 Mar 2004||20 Jun 2006||Regents Of The University Of Minnesota||Implantable reservoir and system for delivery of a therapeutic agent|
|US7242982||9 Dic 2003||10 Jul 2007||Medtronic, Inc.||Overmold for a modular implantable medical device|
|US7263401||29 Abr 2004||28 Ago 2007||Medtronic, Inc.||Implantable medical device with a nonhermetic battery|
|US7317947||29 Abr 2004||8 Ene 2008||Medtronic, Inc.||Headset recharger for cranially implantable medical devices|
|US7481816||27 Oct 2003||27 Ene 2009||Optonol Ltd.||Intraocular implant, delivery device, and method of implantation|
|US7596399||29 Abr 2004||29 Sep 2009||Medtronic, Inc||Implantation of implantable medical device|
|US7596408||30 Abr 2004||29 Sep 2009||Medtronic, Inc.||Implantable medical device with anti-infection agent|
|US7670310||7 Dic 2007||2 Mar 2010||Optonol Ltd||Flow regulating implants|
|US7813811||8 Feb 2007||12 Oct 2010||Neuropace, Inc.||Refillable reservoir lead systems|
|US7844345||8 Feb 2007||30 Nov 2010||Neuropace, Inc.||Drug eluting lead systems|
|US7862531||25 Jun 2004||4 Ene 2011||Optonol Ltd.||Flow regulating implants|
|US7881796||31 Jul 2007||1 Feb 2011||Medtronic, Inc.||Implantable medical device with a nonhermetic battery|
|US8034016||7 Dic 2007||11 Oct 2011||Optonol, Ltd.||Flow regulating implants and methods of implanting|
|US8062270 *||23 Jun 2010||22 Nov 2011||Spinal Generations, Llc||Method and device for delivering medicine to bone|
|US8086313||5 Ago 2009||27 Dic 2011||Medtronic, Inc.||Implantable medical device with anti-infection agent|
|US8109896||11 Feb 2008||7 Feb 2012||Optonol Ltd.||Devices and methods for opening fluid passageways|
|US8152792 *||8 Sep 2008||10 Abr 2012||Kornel Ezriel E||Subcutaneous drain for a body cavity|
|US8160720||13 Sep 2010||17 Abr 2012||Neuropace, Inc.||Refillable reservoir lead systems|
|US8190270||10 Ene 2012||29 May 2012||Neuropace, Inc.||Refillable reservoir lead systems|
|US8280478||10 Ago 2009||2 Oct 2012||Medtronic, Inc.||Evaluation of implantation site for implantation of implantable medical device|
|US8313454||26 Mar 2010||20 Nov 2012||Optonol Ltd.||Fluid drainage device, delivery device, and associated methods of use and manufacture|
|US8423156||9 Feb 2012||16 Abr 2013||Neuropace, Inc.||Drug eluting lead systems|
|US8486086||7 Nov 2011||16 Jul 2013||Optonol, Ltd||Flow regulating implant, method of manufacture, and delivery device|
|US8808337||21 Abr 2009||19 Ago 2014||Spinal Generations, Llc||Method and device for delivering medicine to bone|
|US8870836||7 Sep 2011||28 Oct 2014||Spinal Generations, Llc||Method and device for delivering medicine to bone|
|US9084901||28 Abr 2006||21 Jul 2015||Medtronic, Inc.||Cranial implant|
|US9162072||25 Sep 2006||20 Oct 2015||Medtronic, Inc.||Implantable medical device with lubricious material|
|US9173774||11 Sep 2012||3 Nov 2015||Optonol Ltd.||Fluid drainage device, delivery device, and associated methods of use and manufacture|
|US20030079329 *||9 Dic 2002||1 May 2003||Ira Yaron||Flow regulating implant, method of manufacture, and delivery device|
|US20040088048 *||27 Oct 2003||6 May 2004||Jacob Richter||Intraocular implant, delivery device, and method of implantation|
|US20040176750 *||16 Mar 2004||9 Sep 2004||Isurgical, Llc And Regents Of The University Of Minnesota||Implantable reservoir and system for delivery of a therapeutic agent|
|US20040176814 *||9 Dic 2003||9 Sep 2004||Ruchika Singhal||Overmold for a modular implantable medical device|
|US20050003268 *||29 Abr 2004||6 Ene 2005||Scott Erik R.||Battery housing configuration|
|US20050004618 *||29 Abr 2004||6 Ene 2005||Scott Erik R.||Implantable medical device with a nonhermetic battery|
|US20050004619 *||29 Abr 2004||6 Ene 2005||Wahlstrand Carl D.||Headset recharger for cranially implantable medical devices|
|US20050004620 *||30 Abr 2004||6 Ene 2005||Medtronic, Inc.||Implantable medical device with anti-infection agent|
|US20050004637 *||29 Abr 2004||6 Ene 2005||Ruchika Singhal||Explantation of implantable medical device|
|US20050240155 *||27 Abr 2004||27 Oct 2005||Conlon Sean P||Surgically implantable injection port having a centered catheter connection tube|
|US20050240156 *||27 Abr 2004||27 Oct 2005||Conlon Sean P||Method of implanting a fluid injection port|
|US20050245806 *||29 Abr 2004||3 Nov 2005||Ruchika Singhal||Implantation of implantable medical device|
|US20050245984 *||30 Abr 2004||3 Nov 2005||Medtronic, Inc.||Implantable medical device with lubricious material|
|US20050288617 *||25 Jun 2004||29 Dic 2005||Ira Yaron||Flow regulating implants|
|US20060184210 *||13 Abr 2006||17 Ago 2006||Medtronic, Inc.||Explantation of implantable medical device|
|US20060195156 *||13 Abr 2006||31 Ago 2006||Medtronic, Inc.||Explantation of implantable medical device|
|US20060253106 *||9 May 2006||9 Nov 2006||Regents Of The University Of Minnesota, Isurgical, Llc||Implantable reservoir and system for delivery of a therapeutic agent|
|US20070074732 *||25 Sep 2006||5 Abr 2007||Medtronic, Inc.||Implantable medical device with lubricious material|
|US20070185539 *||16 Abr 2007||9 Ago 2007||Medtronic, Inc.||Overmold for a modular implantable medical device|
|US20070255338 *||28 Abr 2006||1 Nov 2007||Medtronic, Inc.||Cranial implant|
|US20080065173 *||13 Nov 2007||13 Mar 2008||Medtronic, Inc.||Headset recharger for cranially implantable medical devices|
|US20080125691 *||7 Dic 2007||29 May 2008||Optonol Ltd.||Flow regulating implants|
|US20120232501 *||22 May 2012||13 Sep 2012||Std Med, Inc.||Volume Reducing Reservoir Insert for an Infusion Port|
|DE2124062A1 *||14 May 1971||23 Dic 1971||Título no disponible|
|DE2724231A1 *||25 May 1977||30 Nov 1978||Affeld Klaus||Collecting container for spermatozoa - includes suture ring implanted over epididymis and tube leading to tap capsule|
|EP0134340A1 *||22 Ago 1983||20 Mar 1985||The University of Utah Research Foundation||Peritoneal injection catheter apparatus|
|EP0134745A1 *||31 Ago 1984||20 Mar 1985||Henri Meriaux||Infusion device|
|EP0309092A1 *||19 Ago 1988||29 Mar 1989||Infusaid, Inc.||Implantable device|
|EP0822844A1 *||15 Abr 1996||11 Feb 1998||Medtronic, Inc.||Securing device for intercranial infusion port with filter and catheter|
|EP1426074A1 *||15 Abr 1996||9 Jun 2004||Medtronic Inc.||Securing device for intracranial infusion port with filter and catheter|
|EP1591140A1||26 Abr 2005||2 Nov 2005||Ethicon Endo-Surgery, Inc.||A surgically implantable injection port having a centered catheter connection tube|
|WO1990014857A1 *||7 Jun 1990||13 Dic 1990||Univ California||Method and apparatus for intraosseous infusions and aspirations|
|WO1996014834A1 *||9 Nov 1995||23 May 1996||Univ Kentucky Res Found||Implantable refillable controlled release device to deliver drugs directly to an internal portion of the body|
|Clasificación de EE.UU.||604/175, 604/212|
|Clasificación cooperativa||A61M39/0208, A61M2210/0687|
|22 Feb 1983||AS||Assignment|
Owner name: AMERICAN HOSPITAL SUPPLY CORPORATION; ONE AMERICAN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:AMERICAN HEYER- SCHULTE CORPORATION;REEL/FRAME:004099/0695
Effective date: 19830121