Búsqueda Imágenes Maps Play YouTube Noticias Gmail Drive Más »
Búsqueda avanzada de patentes | Historial web | Iniciar sesión

Patentes

Citada por

Patente citante Fecha de presentación Fecha de emisión Cesionario original Título
US42922997 Jul 198029 Sep 1981Teijin LimitedSlow-releasing medical preparation to be administered by adhering to a wet mucous surface
US443296427 Dic 198221 Feb 1984ALZA CorporationTopical composition containing steroid in two forms released independently from polymeric carrier
US44788185 Ene 198423 Oct 1984Alza CorporationOcular preparation housing steroid in two different therapeutic forms
US466703210 Oct 198519 May 1987Merck Frosst Canada, Inc.Phenothiazone derivatives and analogs
US476437810 Feb 198616 Ago 1988Zetachron, Inc.Buccal drug dosage form
US485966714 Ene 198722 Ago 1989Merck Frosst Canada, Inc.Pharmaceutical compositions of phenothiazone derivatives and analogs
US488972031 Ago 198726 Dic 1989Teikoku Seiyaku Kabushiki KaishaSustained release dosage form for use with tissues of the oral cavity
US48927363 Jun 19889 Ene 1990The Forsyth Dental Infirmary for ChildrenIntra-pocket drug delivery devices for treatment of periodontal diseases
US496987115 Feb 198913 Nov 1990Alza CorporationIntravenous system for delivering a beneficial agent
US498501615 Feb 198915 Ene 1991ALZA CorporationIntravenous system for delivering a beneficial agent
US50173716 Ene 198821 May 1991Amarillo Cell Culture Company, IncorporatedMethod for reducing side effects of cancer therapy
US501938217 Ene 199028 May 1991The Texas A&M University SystemTreatment of immuno-resistant disease with low-dose interferon
US504505915 Ago 19903 Sep 1991Alza CorporationIntravenous system for delivering a beneficial agent
US510489913 Ago 199014 Abr 1992Sepracor, Inc.Methods and compositions for treating depression using optically pure fluoxetine
US516032012 Ago 19913 Nov 1992Alza CorporationIntravenous system for delivering a beneficial agent
US517330228 Sep 199022 Dic 1992Medtronic, Inc.Hydrophilic pressure sensitive adhesive for topical administration of hydrophobic drugs
US52500289 Ago 19915 Oct 1993ALZA CorporationIntravenous system for delivering a beneficial agent using permeability enhancers
US541005420 Jul 199325 Abr 1995Merck Frosst Canada, Inc.Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
US558951115 Abr 199431 Dic 1996Sepracor Inc.Method for treating migraine headaches using optically pure S(+) fluoxetine
US56483967 Jun 199515 Jul 1997Sepracor Inc.Methods for treating depression and other disorders using optically pure R (-) fluoxetine and monoamine oxidase inhibitor
US570803522 May 199513 Ene 1998Sepracor Inc.
McLean Hospital
Methods of use and compositions of R(-) fluoxetine
US583045613 Sep 19943 Nov 1998The Texas A&M University SystemTreatment of viral disease with oral interferon-.alpha.
US591030428 Abr 19928 Jun 1999Texas A&M University SystemLow-dose oral administration of interferons
US593942628 Feb 199717 Ago 1999Sepracor Inc.Methods for treating urinary incontinence using descarboethoxyloratadine
US59624646 Jul 19985 Oct 1999Sepracor Inc.Methods and compositions for treating allergic asthma using descarboethoxyloratadine
US604887914 Jun 199911 Abr 2000Sepracor Inc.Methods for treating apnea, apnea disorders, bulimia, and other disorders using optically pure (+) norcisapride
US605446317 Mar 199925 Abr 2000Sepracor Inc.Methods for treating dermatitis using descarboethoxyloratadine
US61002747 Jul 19998 Ago 2000Schering Corporation8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
US611097328 Ene 199929 Ago 2000SepracorMethods for treating obesity and weight gain using optically pure (-)-bupropion
US611434622 Oct 19995 Sep 2000Schering CorporationTreating sleep disorders using desloratadine
US619778827 Sep 19996 Mar 2001Vernalis Research Limited(-)-mefloquine to block puringergic receptors and to treat movement or neurodegenerative disorders
US62654143 May 200024 Jul 2001Schering CorporationTreating sleep disorders using desloratadine
US627788720 Abr 200021 Ago 2001Sepracor, Inc.Methods for treating Parkinson's disease using optically pure (-)-bupropion
US633157111 Ago 199918 Dic 2001Sepracor, Inc.Methods of treating and preventing attention deficit disorders
US633732818 Ago 20008 Ene 2002Sepracor, Inc.Bupropion metabolites and methods of use
US633910614 Sep 200015 Ene 2002Sepracor, Inc.Methods and compositions for the treatment and prevention of sexual dysfunction
US634249622 Feb 200029 Ene 2002Sepracor Inc.Bupropion metabolites and methods of use
US634253330 Nov 199929 Ene 2002Sepracor, Inc.Derivatives of (
US635300522 Feb 20005 Mar 2002Sepracor, Inc.Method and compositions using (
US636907929 Feb 20009 Abr 2002Sepracor, Inc.Methods for treating irritable bowel syndrome using optically pure (
US636911327 Jun 20019 Abr 2002Sepracor, Inc.Method for treating depression using optically pure (
US639982611 Ene 20004 Jun 2002Sepracor Inc.Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
US641005210 Ago 200025 Jun 2002Purdue Research Foundation
Pharmanex, Inc.
Tea catechins in sustained release formulations as cancer specific proliferation inhibitors
US642881817 Ago 20006 Ago 2002Purdue Research Foundation
Pharmanex, Inc.
Tea catechin formulations and processes for making same
US64324461 Feb 200113 Ago 2002Bridge Pharma, Inc.Non-arrhythmogenic metabolite of oxybutynin
US645186019 Feb 200217 Sep 2002Sepracor, Inc.Methods for treating depression and other disorders using optically pure (
US645837428 Ene 19991 Oct 2002Sepracor, Inc.Methods and compositions for treating chronic disorders using optically pure (
US647607829 Ene 20015 Nov 2002Sepracor, Inc.Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US649560513 Mar 200117 Dic 2002Sepracor Inc.Methods and compositions for aiding in smoking cessation and for treating pain and other disorders using optically pure (
US65380344 Dic 200125 Mar 2003Methods of treating or preventing weight gain, obesity, and related disorders
US654808229 Feb 200015 Abr 2003Sepracor Inc.Methods for treating apnea and apnea disorders using optically pure R(
US654851810 Ene 200215 Abr 2003Sepracor, Inc.Methods of treating gastro-esophogeal reflux disease using (-) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
US655204510 Ene 200222 Abr 2003Sepracor Inc.Methods and compositions using (
US655916528 Nov 20006 May 2003Sepracor, Inc.Methods for treating bulimia using optically pure (
US655918815 Sep 20006 May 2003Novartis AGMethod of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
US661088712 Abr 200226 Ago 2003Sepracor Inc.Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US66491831 Nov 200118 Nov 2003Sepracor Inc.Methods for treating apnea and apnea disorders using optically pure R(
US666439722 Nov 199916 Dic 2003Vernalis Research LimitedUse of (
US670967619 Jun 200223 Mar 2004Schering CorporationExtended release oral dosage composition
US67100874 Jun 200223 Mar 2004Sepracor, Inc.Methods of treating or preventing neuropathic pain using sibutramine metabolites
US673421317 May 200211 May 2004Smithkline Beecham CorporationPharmaceutically active morpholinol
US682520524 Sep 200330 Nov 2004Euro-Celtique S.A.N-substituted hydromorphones and the use thereof
US683574015 Feb 200228 Dic 2004Sepracor Inc.Methods for treating sleep apnea and sleep induced apnea using optically pure (
US685582017 May 200215 Feb 2005SmithKline Beecham CorporationPharmaceutically active morpholinol
US685858923 Jul 200222 Feb 2005Pharmacy and Therapeutic Advisory Consultancy Pty LTDMethods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria
US687871312 Dic 200212 Abr 2005Wockhardt LimitedGeneration triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US687874916 Ene 200312 Abr 2005Novartis AGMethod of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
US689418920 Ago 200317 May 2005Sepracor Inc.Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US691147919 Ago 200228 Jun 2005Sepracor Inc.Methods of treating and preventing pain, anxiety, and incontinence using derivatives of (−)-venlafaxine
US69518733 Mar 20004 Oct 2005Pfizer Inc.Methods for treating age-related behavioral disorders in companion animals
US696496623 Abr 200215 Nov 2005Wockhardt LimitedGeneration triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US697483723 Oct 200213 Dic 2005Sepracor Inc.Compositions comprising sibutramine metabolites in combination with phosphodiesterase inhibitors
US697483823 Mar 200413 Dic 2005Sepracor Inc.Methods of treating or preventing pain using sibutramine metabolites
US697946319 Jun 200227 Dic 2005Schering CorporationStable extended release oral dosage composition
US699516829 May 20037 Feb 2006Euro-Celtique S.A.Triazaspiro compounds useful for treating or preventing pain
US699840017 May 200214 Feb 2006Smithkline Beecham CorporationPharmaceutically active morpholinol
US701903017 Jul 200328 Mar 2006Celgene CorporationImmunotherapeutic agents
US703405928 Jun 200225 Abr 2006Sepracor Inc.Methods of using norfluoxetine
US706413826 Feb 200320 Jun 2006Sepracor Inc.Methods for treating irritable bowel syndrome using optically pure (-) norcisapride
US707123425 Mar 20034 Jul 2006Sepracor Inc.Methods of treating or preventing erectile dysfunction
US709820617 May 200229 Ago 2006SmithKline Beecham CorporationPharmaceutically active morpholinol
US710533327 Mar 200212 Sep 2006Deadreon CorporationNucleic acid molecules encoding a transmembrane serine protease 9, the encoded polypeptides and methods based thereon
US711243014 May 200226 Sep 2006Dendreon CorporationNucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
US712570313 Mar 200224 Oct 2006Dendreon CorporationNucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
US714169621 May 200428 Nov 2006Bridge Pharma, Inc.Smooth muscle spasmolytic agents
US716402331 Dic 200316 Ene 2007Wockhardt LimitedBenzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
US717289220 Mar 20026 Feb 2007Dendreon CorporationNucleic acid molecules encoding serine protease CVSP14, the encoded polypeptides and methods based thereon
US71762187 Ene 200513 Feb 2007ARYx TherapeuticsStereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US718295311 Dic 200027 Feb 2007Celgene CorporationMethods and compositions for the prevention and treatment of atherosclerosis restenosis and related disorders
US718686321 May 20046 Mar 2007TransForm Pharmaceuticals, Inc.Sertraline compositions
US718974011 Abr 200313 Mar 2007Celgene CorporationMethods of using 3-(4-amino-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myelodysplastic syndromes
US72054131 May 200317 Abr 2007TransForm Pharmaceuticals, Inc.Solvates and polymorphs of ritonavir and methods of making and using the same
US721158223 Nov 19991 May 2007Sepracor Inc.Methods for treating urticaria using descarboethoxyloratadine
US721468316 Mar 19988 May 2007Sepracor Inc.Compositions of descarboethoxyloratadine
US721468417 Nov 20048 May 2007Sepracor Inc.Methods for the treatment of allergic rhinitis
US722964018 Dic 200112 Jun 2007SmithKline Beecham p.l.c.Paroxetine controlled release compositions
US72591524 Jun 200121 Ago 2007Alfa Wasserman, Inc.Methods and compositions using sulodexide for the treatment of diabetic nephropathy
US727636420 Nov 20002 Oct 2007Dendreon CorporationNucleic acids encoding endotheliases, endotheliases and uses thereof
US728250923 Mar 200516 Oct 2007Aryx TherapeuticsStereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US729134718 Ene 20066 Nov 2007WyethSuccinate salt of O-desmethyl-venlafaxine
US73234796 Nov 200329 Ene 2008Celgene CorporationMethods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline
US732348024 May 200529 Ene 2008Metabolex, Inc.Substituted triazoles as modulators of PPAR and methods of their preparation
US732678731 Ago 20065 Feb 2008ARYx Therapeutics, Inc.Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
US732976116 Nov 200412 Feb 2008Celgene CorporationSubstituted imides
US735173929 Abr 20051 Abr 2008Wellgen, Inc.
The Regents of the University of Minnesota
Rutgers, the State University of New Jersey
Bioactive compounds and methods of uses thereof
US73549486 Nov 20038 Abr 2008Celgene CorporationMethods for treatment of chronic uveitis using cyclopropyl-n-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide
US735789130 Ene 200415 Abr 2008MonoSol Rx, LLCProcess for making an ingestible film
US73582467 Abr 200515 Abr 2008WyethThioamide derivatives as progesterone receptor modulators
US73938624 Oct 20051 Jul 2008Celgene CorporationMethod using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
US739386316 Ene 20071 Jul 2008Celgene CorporationMethods of using N-{[2-(2,6-dioxo(3-piperidyl)-1,3-dioxoisoindolin-4-yl]methyl}cyclopropyl-carboxamide for the treatment and management of myelodysplastic syndromes
US739395720 Sep 20041 Jul 2008Wockhardt LimitedGeneration triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US740522316 Ene 200129 Jul 2008Schering CorporationTreating allergic and inflammatory conditions
US741406216 Jun 200519 Ago 2008Purdue Pharma L.P.Triazaspiro compounds useful for treating or preventing pain
US742529214 Feb 200216 Sep 2008MonoSol Rx, LLCThin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US74389037 May 200421 Oct 2008NBTY, Inc.Methods and compositions that enhance bioavailability of coenzyme-Q10
US74658003 Sep 200416 Dic 2008Celgene CorporationPolymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US74683638 Abr 200523 Dic 2008Celgene CorporationMethods for treatment of cancers using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
US747043517 Nov 200330 Dic 2008Andrx Pharmaceuticals, LLCExtended release venlafaxine formulation
US75110717 Mar 200831 Mar 2009WyethThioamide derivatives as progesterone receptor modulators
US751446625 Abr 20057 Abr 2009WyethPurification of progesterone receptor modulators
US751458330 May 20037 Abr 2009Proteotech, Inc.Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease
US751801731 Ene 200714 Abr 2009Idexx LaboratoriesFenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US757281220 Ene 200611 Ago 2009Therapeutic agents useful for treating pain
US758263519 Dic 20031 Sep 2009Therapeutic agents useful for treating pain
US759233512 Abr 200622 Sep 2009Ranbaxy Laboratories LimitedOxazolidinone derivatives as antimicrobials
US761209623 Abr 20043 Nov 2009Celgene CorporationMethods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
US76186493 Nov 200317 Nov 2009Schering CorporationExtended release oral dosage composition
US762603224 Abr 20081 Dic 2009Wockhardt LimitedGeneration triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US762946625 Abr 20088 Dic 2009ARYx Therapeutics, Inc.Synthetic methods and intermediates for steroisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
US76422875 Ago 20055 Ene 2010Transform Pharmaceuticals, Inc.Statin pharmaceutical compositions and related methods of treatment
US765926512 Feb 20099 Feb 2010WyethThioamide derivatives as progesterone receptor modulators
US765928212 Ene 20059 Feb 2010Avanir Pharmaceuticals, Inc.Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
US765928731 May 20079 Feb 2010Amgen Inc.Benzamide derivatives and uses related thereto
US766633728 May 200423 Feb 2010MonoSol Rx, LLCPolyethylene oxide-based films and drug delivery systems made therefrom
US767109327 May 20052 Mar 2010Transform Pharmaceuticals, Inc.Mixed co-crystals and pharmaceutical compositions comprising the same
US768306314 Jun 200423 Mar 2010Purdue Pharma L.P.Therapeutic agents useful for treating pain
US769620831 Ene 200613 Abr 2010Purdue Pharma L.P.Therapeutic agents useful for treating pain
US77003412 Feb 200120 Abr 2010Dendreon CorporationNucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
US772802528 Dic 20041 Jun 2010Banyu Pharmaceutical Co., Ltd.2-heteroaryl-substituted benzimidazole derivative
US775472328 Jun 200613 Jul 2010Therapeutic agents useful for treating pain
US77674295 Mar 20043 Ago 2010Halozyme, Inc.Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US776769922 Dic 20053 Ago 2010Purdue Pharma, L.P.Therapeutic agents useful for treating pain
US777220627 Feb 200910 Ago 2010Genzyme CorporationMethods and compositions for the treatment of autoimmune disorders using clofarabine
US777225421 Mar 200610 Ago 2010Purdue Pharma L.P.Therapeutic agents useful for treating pain
US777686123 Ene 200617 Ago 2010Purdue Pharma L.P.Therapeutic agents useful for treating pain
US777690730 Oct 200317 Ago 2010Celgene CorporationMethods for the treatment and management of macular degeneration using cyclopropyl-N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide
US779090529 Dic 20037 Sep 2010McNeil-PPC, Inc.Pharmaceutical propylene glycol solvate compositions
US779980720 Mar 200621 Sep 2010Purdue Pharma L.P.Therapeutic agents useful for treating pain
US779982029 Sep 200621 Sep 2010Banyu Pharmaceutical Co., Ltd.2-Heterocycle-substituted indole derivatives for treating diabetes and associated conditions
US780336625 Ago 200828 Sep 2010NBTY, Inc.Methods and compositions that enhance bioavailability of coenzyme-Q10
US780378616 Jun 200528 Sep 2010Transform Pharmaceuticals, Inc.
University of South Florida
Pharmaceutical co-crystal compositions and related methods of use
US781216930 Nov 200112 Oct 2010The Children's Medical Center CorporationMethod of synthesis of 4-amino-thalidomide enantiomers
US78201996 Oct 200526 Oct 2010Schering CorporationStable extended release oral dosage composition
US782458814 Abr 20082 Nov 2010Monosol RX, LLCMethod of making self-supporting therapeutic active-containing film
US78290814 Mar 20109 Nov 2010Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US784269113 Abr 200330 Nov 2010Celgene CorporationMethod for the treatment of myelodysplastic syndromes using cyclopropanecarboxylic acid {2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-OXO-2,3-dihydro-1 H-isoindol-4-yl}-amide
US78464314 Mar 20107 Dic 2010Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US785521715 Dic 200821 Dic 2010Celgene CorporationPolymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US786329712 Nov 20074 Ene 2011Celgene CorporationMethods of using 4-(amino)-2-(2,6-dioxo(3-piperidly))-isoindoline-3-dione for the treatment of myelodysplastic syndromes
US787160723 Feb 200518 Ene 2011Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US788809230 Oct 200915 Feb 2011Dendreon CorporationNucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
US78927765 May 200822 Feb 2011The Regents of the University of CaliforniaScreening assay to identify modulators of protein kinase A
US78930455 Ago 200822 Feb 2011Celgene CorporationMethods for treating lymphomas in certain patient populations and screening patients for said therapy
US790220830 May 20088 Mar 2011Schering CorporationTreating allergic and inflammatory conditions
US791064114 Dic 200622 Mar 2011Monosol Rx, LLCPH modulated films for delivery of actives
US792761311 Sep 200319 Abr 2011University of South Florida
The Regents of the University of Michigan
Transform Pharmaceuticals, Inc.
Pharmaceutical co-crystal compositions
US79281326 Ago 200419 Abr 2011Ohio UniversityMethods for the amelioration of episodes of acute or chronic ulcerative colitis
US793191519 Nov 200826 Abr 2011Andrx Pharmaceuticals, LLCExtended release venlafaxine formulation
US793242112 Dic 200726 Abr 2011Amgen Inc.N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
US796460629 Jul 201021 Jun 2011Purdue Pharma L.P.Therapeutic agents useful for treating pain
US796856915 May 200328 Jun 2011Celgene CorporationMethods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
US797261820 Sep 20075 Jul 2011MonoSol Rx, LLCEdible water-soluble film containing a foam reducing flavoring agent
US797735723 Jul 200812 Jul 2011Celgene CorporationPolymorphic forms of 3-(4-amino-1-oxo-1, 3 dihydro-isoindo1-2-yl)-piperidine-2,6-dione
US799417721 Jul 20109 Ago 2011Purdue Pharma L.P.Therapeutic agents useful for treating pain
US80083008 Jul 200930 Ago 2011Purdue Pharma L.P.Therapeutic agents useful for treating pain
US801715022 Abr 200813 Sep 2011MonoSol Rx, LLCPolyethylene oxide-based films and drug delivery systems made therefrom
US802625410 Nov 200927 Sep 2011Purdue Pharma, L.P.Therapeutic agents useful for treating pain
US80303102 Mar 20104 Oct 2011Purdue Pharma, L.P.Therapeutic agents useful for treating pain
US805829224 May 201015 Nov 2011Purdue Pharma L.P.Therapeutic agents useful for treating pain
US805844315 Dic 200815 Nov 2011Celgene CorporationProcesses for preparing polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-YL))-piperidine-2,6-dione
US806322113 Mar 200722 Nov 2011Kyorin Pharmaceutical Co., Ltd.Aminoquinolones as GSK-3 inhibitors
US807159110 Mar 20106 Dic 2011Kyorin Pharmaceutical Co., Ltd.7-cycloalkylaminoquinolones as GSK-3 inhibitors
US810174515 Dic 200524 Ene 2012The Regents of the University of CaliforniaLung-targeted drugs
US810558615 Jun 201031 Ene 2012Halozyme, Inc.Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US811060215 Jul 20097 Feb 2012Purdue Pharma L.P.Compounds comprising heterocyclic-substituted piperidine for treating pain
US812938810 Jun 20116 Mar 2012Purde Pharma L.P.Therapeutic agents useful for treating pain
US813820416 Jul 200720 Mar 2012ARYx Therapeutics, Inc.Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
US813836127 Dic 200620 Mar 2012The Trustees Of The University Of Pennsylvania
Acidophil, LLC
C-10 carbamates of taxanes
US814328615 Dic 200827 Mar 2012Celgene CorporationPolymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione)
US815380616 Jul 201010 Abr 2012The Children's Medical Center CorporationSynthesis of 4-amino-thalidomide enantiomers
US816395716 Jul 201024 Abr 2012ProteoTech, Inc.Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes and parkinson's disease
US816863520 Jun 20051 May 2012Human BioMolecular Research InstituteModulators of central nervous system neurotransmitters
US81686722 Feb 20101 May 2012WyethThioamide derivatives as progesterone receptor modulators
US817856017 Jun 201015 May 2012Purdue Pharma L.P.Therapeutic agents useful for treating pain
US818329020 Jul 201022 May 2012McNeil-PPC, Inc.Pharmaceutically acceptable propylene glycol solvate of naproxen
US818338110 Jul 200822 May 2012Metabolex Inc.N-linked heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders
US81876302 Oct 200929 May 2012Schering-Plough CorporationExtended release oral dosage composition
US818811819 Feb 200929 May 2012Celgene CorporationMethod for treating multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione in combination with antibodies
US81932193 Oct 20115 Jun 2012Celgene CorporationPolymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US819826219 Ago 200812 Jun 2012Celgene CorporationMethods for treating multiple myeloma using 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione
US819830617 Dic 200912 Jun 2012Celgene CorporationMethods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione in combination with a proteasome inhibitor
US820251720 Feb 200919 Jun 2012Halozyme, Inc.Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US82029996 Ene 200619 Jun 2012Synta Pharmaceuticals Corp.Compounds for inflammation and immune-related uses
US82072008 May 200826 Jun 2012Celgene CorporationMethods for treating multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydroindol-2-yl)-piperidine-2,6-dione follow by autologous stem cell transplantation
US82114285 Jul 20073 Jul 2012Torrey Pines Institute for Molecular Studies
Catalyst Biosciences, Inc.
Protease screening methods and proteases identified thereby
US822225730 Mar 200617 Jul 2012The Regents of the University of CaliforniaPhosphono-pent-2-en-1-yl nucleosides and analogs
US822746716 Feb 201024 Jul 2012Purdue Pharma L.P.Therapeutic agents useful for treating pain
US82274848 Mar 201224 Jul 2012Avanir Pharmaceuticals, Inc.Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders