US3625212A - Eliminating mistakes in plasmapheresis - Google Patents

Eliminating mistakes in plasmapheresis Download PDF

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US3625212A
US3625212A US840154A US3625212DA US3625212A US 3625212 A US3625212 A US 3625212A US 840154 A US840154 A US 840154A US 3625212D A US3625212D A US 3625212DA US 3625212 A US3625212 A US 3625212A
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container
donor
plug
receptacle
red blood
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US840154A
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Ralph Rosenberg
Sheldon Reich
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North American Biologicals Inc
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North American Biologicals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1414—Hanging-up devices
    • A61M5/1415—Stands, brackets or the like for supporting infusion accessories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means

Definitions

  • this disclosure teaches a method for eliminating mistakes in returning a container of red blood cells to the correct donor.
  • a mating plug and receptacle of distinctive shape are connected between the container and its support. If the plug and receptacle do not match, there is no convenient way to support the container for intravenous delivery of the red blood cells to the donor.
  • the basic concept can be applied also to a wide variety of other services.
  • Plasmapheresis is a method of obtaining plasma from a blood donor by extracting blood, centrifuging the blood to remove plasma and then returning red blood cells to him.
  • a critical danger in plasmapheresis is that the red blood cells might be retumedby mistake to the wrong donor. Such a mistake could result in serious complications or even death.
  • safety checks used in plasmapheresis have been entirely visual and have included matching of donor numbers with cot numbers or matching colors. But these safety checks are subject to obvious human mistakes and other limitations.
  • one object of this invention is to detect a mismatch by physical means.
  • Another object is to render the blood container physically unsupportable in the event there is a mismatch.
  • Another object is to make these matches relatively independent from human shortcomings such as inattention, boredom and color blindness.
  • Another object is to be able to centrifuge the blood container along with the plug, without damage to the blood container or impairment of centrifugal separation.
  • Another object is to provide plug and receptacle configurations and sizes such that each plug is able to be fitted into its corresponding receptacle and none other, even by force or turning.
  • FIG. 1 is a plug receptacle pair according to the present invention.
  • FIGS. 2, 3 and 4 depict a cot and associated stand suitable for blood donating, with FIG. 2 showing the plasmapheresis situation before donating, FIG. 3 showing the situation when a supply of blood is taken from the donor and FIG. 4 showing the situation when red blood cells and saline solution are returned to the donor.
  • FIGS. 5, 6 and 7 illustrate other suitable plug and receptacle pairs.
  • FIGS. 8 and 9 show receptacles with numeral and letter coding.
  • the donor usually reclines on a cot 11 (or the like) which is provided with hook 12 below the level of the donor for receiving whole blood from one of the donor's arms via tube 13.
  • Stand 14 is also provided and it has hooks l and 16 for supporting solid blood constituents and saline solution respectively for subsequent intravenous delivery to the donor via tubes 17 and 18.
  • hook 16 and saline container 25 so that hook 16 can accommodate only saline container 25, and not blood container 19.
  • FIGS. 2, 3 and 4 cot I1 and stand 14, with member 23 depending from hook by means of closed link 26, are prepared for the donor. Plug 21 is in place in receptacle 24 and is retained therein by latch 27 rotatable about pin 28. Blood container 19 has loops 29 and 31 at its ends 32 and 33 respectively. In taking whole blood from the donor, blood container 19 is hung on hook 12 by means of closed link 34 and loop 29.
  • the technician then removes plug 21 from receptacle 24 and connects the plug by means of snap link 35 onto loop 31 of blood container .19.
  • the supply of whole blood is taken from the donor, it is removed (with plug 21 connected to it) for centrifuging to separate plasma therefrom. This centrifuging is accomplished with plug 24 connected to loop 21 of blood container 19.
  • red blood cells of the blood are returned to the area in container 19 which the technician hangs on stand 14 by opening latch 27, inserting plug 21 into receptacle 24 and closing latch 27.
  • member 23 includes back 36 which cooperates with latch 27 for holding plug 21 in position.
  • Saline container 25 is hung from hook 116 and a mixture of red blood cells and saline solution is introduced intravenously to the donor via tubes 17 and 18 to complete the plasmapheresis procedure.
  • this invention contemplates plugs of a wide variety of shapes. Plugs may be coded according to numerals and or letters as shown by receptacle 23 in FIGS. 8 and 9. It is most important that plug and receptacle configurations and sizes be selected such that each plug is able to be fitted into its corresponding receptacle and none other even by force or turning. Support for blood container 19 requires that plug 19 have a reasonable broad horizontal abutment 37 on which to seal plug 21.
  • a method for avoiding mistakes in matching a patient to substance to be administered comprising the steps of arranging a connection position relative to the patient in which position a container having the substance therein must be placed for administering the substance to the patient,
  • a method for perfonning plasmapheresis comprising the steps of arranging an elevated support relative to the donor in which support a container having red blood cells therein must be placed for intravenous return of the red blood cells to the donor,
  • a receptacle which has a shape which conforms to the cross-sectional shape of the plug, and thereafter inserting the plug into the receptacle to position the blood container on the support for intravenous delivery of the red blood cells to the donor.

Abstract

In plasmapheresis, this disclosure teaches a method for eliminating mistakes in returning a container of red blood cells to the correct donor. A mating plug and receptacle of distinctive shape are connected between the container and its support. If the plug and receptacle do not match, there is no convenient way to support the container for intravenous delivery of the red blood cells to the donor. The basic concept can be applied also to a wide variety of other services.

Description

United States Patent Ralph Rosenberg Bay Harbor Island;
Sheldon Reich, Hollywood, both of Fla. 840,154
July 9, 1969 Dec. 7, 1971 North American Biologicals, Inc.
Fort Lauderdale, Fla.
Inventors Appl. No. Filed Patented Assignee ELIMINA'IING MISTAKES IN PLASMAPHERESIS 7 Claims, 9 Drawing Figs.
US. Cl 128/214 R Int. Cl ..A6lm 05/00 Field of Search... 128/214, 214.2, 2; 285/D1G. 15
References Cited UNITED STATES PATENTS 9/1954 Adams et a1.
2,896,619 7/1959 Bellamy 128/214 3,145,713 8/1964 Latham 128/214 3,364,930 1/1968 Ryan 128/214 3,407,812 10/1968 Lucas 128/214 3,523,522 8/1970 Whitehead et al..... 128/2 FOREIGN PATENTS 771,968 4/1957 Great Britain 285/D1G. 15
Primary Examiner- Dalton L. Truluck Attorney-Ham: & Baxley ABSTRACT: In plasmapheresis, this disclosure teaches a method for eliminating mistakes in returning a container of red blood cells to the correct donor. A mating plug and receptacle of distinctive shape are connected between the container and its support. If the plug and receptacle do not match, there is no convenient way to support the container for intravenous delivery of the red blood cells to the donor. The basic concept can be applied also to a wide variety of other services.
PATENTEUDEB 71am 3.625212 sum 1 BF 2 SHELDON RE/G BY RALPH ROSE/V85 G Arrow/5K9 PATENTEUDEB 1m 3.625212 SHEET 2 OF 2 FIG. 8 FIG. 9
INVENY'URS Z 5 JHELDON RE /C H BY RALPH ROSENBERG AT my:
ELIMINATING MISTAKES 1N PLASMAPIIERESIS BACKGROUND Plasmapheresis is a method of obtaining plasma from a blood donor by extracting blood, centrifuging the blood to remove plasma and then returning red blood cells to him. A critical danger in plasmapheresis is that the red blood cells might be retumedby mistake to the wrong donor. Such a mistake could result in serious complications or even death. Until the present, safety checks used in plasmapheresis have been entirely visual and have included matching of donor numbers with cot numbers or matching colors. But these safety checks are subject to obvious human mistakes and other limitations.
INVENTION Safety checking of the matching of red blood cells with the proper donor is here accomplished in a novel and facile way. Distinctively shaped receptacles cooperate with matching plugs to detect mismatching. Accordingly, one object of this invention is to detect a mismatch by physical means.
Another object is to render the blood container physically unsupportable in the event there is a mismatch.
Another object is to make these matches relatively independent from human shortcomings such as inattention, boredom and color blindness.
Another object is to be able to centrifuge the blood container along with the plug, without damage to the blood container or impairment of centrifugal separation.
Another object is to provide plug and receptacle configurations and sizes such that each plug is able to be fitted into its corresponding receptacle and none other, even by force or turning.
DRAWINGS The foregoing and other features will appear more fully from the accompanying drawings wherein like numerals refer to like parts and wherein:
FIG. 1 is a plug receptacle pair according to the present invention.
FIGS. 2, 3 and 4 depict a cot and associated stand suitable for blood donating, with FIG. 2 showing the plasmapheresis situation before donating, FIG. 3 showing the situation when a supply of blood is taken from the donor and FIG. 4 showing the situation when red blood cells and saline solution are returned to the donor.
FIGS. 5, 6 and 7 illustrate other suitable plug and receptacle pairs.
FIGS. 8 and 9 show receptacles with numeral and letter coding.
PREFERRED EMBODIMENTS As seen in FIGS. 2-4 during plasmapheresis the donor usually reclines on a cot 11 (or the like) which is provided with hook 12 below the level of the donor for receiving whole blood from one of the donor's arms via tube 13. Stand 14 is also provided and it has hooks l and 16 for supporting solid blood constituents and saline solution respectively for subsequent intravenous delivery to the donor via tubes 17 and 18. In keeping with the principal object of this invention, which is avoiding mistakes in matching correctly red blood cells with their donor, some precautions become important.
It should be made impractical and inconvenient for a technician to hand blood container 19 on stand 14 when plug 21 is not connected properly thereto. Toward this purpose, hook is closed by detent 22 so that support for blood container 19 must be furnished via member 23 in which receptacle 24 is provided. In this regard it would be useful to arrange hook 16 and saline container 25 so that hook 16 can accommodate only saline container 25, and not blood container 19.
Movement of stand 14 from one cot 11 to another must also be avoided at any time plug 21 is out of receptacle 24. This movement can be prevented by attaching stand 14 and cot 11 to the floor or by attaching stand 14 to cot l1. Cot 11 and stand 14 can also be connected detachably with a suitable seal 10 positioned therebetween to indicate disconnection.
At the core of this disclosure is preventing return by mistake of blood container 19, with red blood cells therein, to the wrong stand 14. The preferred procedure for avoiding such a mistake is best seen in the three-step series of illustrations of FIGS. 2, 3 and 4. In FIG. 2, cot I1 and stand 14, with member 23 depending from hook by means of closed link 26, are prepared for the donor. Plug 21 is in place in receptacle 24 and is retained therein by latch 27 rotatable about pin 28. Blood container 19 has loops 29 and 31 at its ends 32 and 33 respectively. In taking whole blood from the donor, blood container 19 is hung on hook 12 by means of closed link 34 and loop 29. The technician then removes plug 21 from receptacle 24 and connects the plug by means of snap link 35 onto loop 31 of blood container .19. When the supply of whole blood is taken from the donor, it is removed (with plug 21 connected to it) for centrifuging to separate plasma therefrom. This centrifuging is accomplished with plug 24 connected to loop 21 of blood container 19.
There remains the step of returning red blood cells of the blood to the donor. These red blood cells are returned to the area in container 19 which the technician hangs on stand 14 by opening latch 27, inserting plug 21 into receptacle 24 and closing latch 27. As best seen in FIG. 1, member 23 includes back 36 which cooperates with latch 27 for holding plug 21 in position. Saline container 25 is hung from hook 116 and a mixture of red blood cells and saline solution is introduced intravenously to the donor via tubes 17 and 18 to complete the plasmapheresis procedure.
As seen in FIGS. 59, this invention contemplates plugs of a wide variety of shapes. Plugs may be coded according to numerals and or letters as shown by receptacle 23 in FIGS. 8 and 9. It is most important that plug and receptacle configurations and sizes be selected such that each plug is able to be fitted into its corresponding receptacle and none other even by force or turning. Support for blood container 19 requires that plug 19 have a reasonable broad horizontal abutment 37 on which to seal plug 21.
Although this invention has been described with particular reference to plasmapheresis, it will be understood that its basic teaching can have wider applications such as in medicine, pharmaceuticals, chemical compounding, solution formulation and the like.
What I claim is:
1. A method for avoiding mistakes in matching a patient to substance to be administered and comprising the steps of arranging a connection position relative to the patient in which position a container having the substance therein must be placed for administering the substance to the patient,
providing a plug having a distinctive configuration,
attaching said plug to said container, providing a receptacle with a configuration which conforms to that of the plug, placing said receptacle in said connection position, and inserting the plug into the receptacle for connection thereto and for supporting the container in said connection position.
2. ln plasmapheresis, a method for avoiding mistakes in returning red blood cells to the correct donor and comprising the steps of arranging an elevated position relative to the donor in which position a container having the donors red blood cells therein must be placed for intravenous delivery of the red blood cells to the donor,
providing a plug which has a distinctive configuration,
attaching said plug to said container,
providing a receptacle which has a configuration that conforms to that of the plug,
placing said receptacle in said elevated position, and
inserting the plug into the receptacle for connection thereto and for holding the container in its elevated position for the intravenous delivery of the red blood cells to the donor.
3. A method for perfonning plasmapheresis and comprising the steps of arranging an elevated support relative to the donor in which support a container having red blood cells therein must be placed for intravenous return of the red blood cells to the donor,
providing a plug which has a distinctive cross-sectional shape,
attaching the plug to a suitable blood container,
withdrawing blood from the donor into the blood container,
extracting plasma from the blood by centrifuging the blood container with the plug attached thereto,
providing on the support a receptacle which has a shape which conforms to the cross-sectional shape of the plug, and thereafter inserting the plug into the receptacle to position the blood container on the support for intravenous delivery of the red blood cells to the donor.
4. The method of claim 3 and delivering saline solution intravenously to the donor along with the red blood cells.
5. The method of claim 4 and providing means for retaining the plug in the receptacle.
the method,
arranging the support adjacent the cot,
providing means for pairing the support with the cot.
7. A method for performing plasmapheresis and comprising the steps of:
providing a stand for suspending thereon a container for red blood cells to be returned to the donor of said cells;
providing an engaging member having a distinctive configuration and a matching receiving member;
assigning said members to the donor;
attaching said engaging member to a container and said receiving member to said stand;
thereafter filling said container with the whole blood donated by the donor and extracting the plasma from the blood by centrifuging; and thereafter inserting said member into said receiving member to suspend said container with the red blood cells therein from the stand for return of the red blood cells to the donor.

Claims (7)

1. A method for avoiding mistakes in matching a patient to a substance to be administered and comprising the steps of arranging a connection position relative to the patient in which position a container having the substance therein must be placed for administering the substance to the patient, providing a plug having a distinctive configuration, attaching said plug to said container, providing a receptacle with a configuration which conforms to that of the plug, placing said receptacle in said connection position, and inserting the plug into the receptacle for connection thereto and for supporting the container in said connection position.
2. In plasmapheResis, a method for avoiding mistakes in returning red blood cells to the correct donor and comprising the steps of arranging an elevated position relative to the donor in which position a container having the donor''s red blood cells therein must be placed for intravenous delivery of the red blood cells back to the donor, providing a plug which has a distinctive configuration, attaching said plug to said container, providing a receptacle which has a configuration that conforms to that of the plug, placing said receptacle in said elevated position, and inserting the plug into the receptacle for connection thereto and for holding the container in its elevated position for the intravenous delivery of the red blood cells to the donor.
3. A method for performing plasmapheresis and comprising the steps of arranging an elevated support relative to the donor in which support a container having red blood cells therein must be placed for intravenous return of the red blood cells to the donor, providing a plug which has a distinctive cross-sectional shape, attaching the plug to a suitable blood container, withdrawing blood from the donor into the blood container, extracting plasma from the blood by centrifuging the blood container with the plug attached thereto, providing on the support a receptacle which has a shape which conforms to the cross-sectional shape of the plug, and thereafter inserting the plug into the receptacle to position the blood container on the support for intravenous delivery of the red blood cells to the donor.
4. The method of claim 3 and delivering saline solution intravenously to the donor along with the red blood cells.
5. The method of claim 4 and providing means for retaining the plug in the receptacle.
6. The method of claim 3 and maintaining the donor on a cot throughout performance of the method, arranging the support adjacent the cot, providing means for pairing the support with the cot.
7. A method for performing plasmapheresis and comprising the steps of: providing a stand for suspending thereon a container for red blood cells to be returned to the donor of said cells; providing an engaging member having a distinctive configuration and a matching receiving member; assigning said members to the donor; attaching said engaging member to a container and said receiving member to said stand; thereafter filling said container with the whole blood donated by the donor and extracting the plasma from the blood by centrifuging; and thereafter inserting said member into said receiving member to suspend said container with the red blood cells therein from the stand for return of the red blood cells to the donor.
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Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3945380A (en) * 1974-08-21 1976-03-23 Cutter Laboratories, Inc. Plasmapheresis assembly
US4091810A (en) * 1975-11-03 1978-05-30 Valleylab Method for intravenous feeding of a patient
US4150673A (en) * 1977-02-03 1979-04-24 Pharmachem Corporation Coded entry system for blood bag
US4547186A (en) * 1983-03-07 1985-10-15 Bartlett Robert H Autotransfusion system
US4619640A (en) * 1984-08-17 1986-10-28 Potolsky Abraham I Blood transfusion connector assembly
US4655741A (en) * 1985-08-27 1987-04-07 Takeo Jyuji Blood component restoration apparatus
EP0217055A1 (en) * 1985-07-31 1987-04-08 Kawasumi Laboratories, Inc. A connector for plasmapheresis bag
US4678458A (en) * 1986-06-09 1987-07-07 Fredeking Terry M Method for avoiding mistakes during plasmapheresis
US4693237A (en) * 1986-01-21 1987-09-15 Hoffman Richard B Radiopaque coded ring markers for use in identifying surgical grafts
US4795434A (en) * 1987-09-10 1989-01-03 C. R. Bard, Inc. Apparatus for positioning a sensor in vivo
US4804363A (en) * 1986-07-16 1989-02-14 Autologous Blood Corporation Apparatus and method for storing and processing blood
USRE33924E (en) * 1986-07-16 1992-05-12 Autologous Blood Corp. Apparatus and method for storing and processing blood
US5725511A (en) * 1995-09-07 1998-03-10 Urrutia; Sharon A. Method and apparatus for prevention of blood-type mismatches
US5863289A (en) * 1993-09-07 1999-01-26 Hoover; Bryan Jay Cross-spike prevention system
US20080077063A1 (en) * 2006-09-21 2008-03-27 Tyco Healthcare Group Lp Safety Connector Apparatus
US8257287B2 (en) 2008-03-20 2012-09-04 Tyco Healthcare Group Lp Safety connector assembly
WO2013085604A1 (en) 2011-12-08 2013-06-13 Econugenics, Inc. Reduction of galectin-3 levels by plasmapheresis
US8764695B2 (en) 2012-09-28 2014-07-01 Isaac Eliaz Reduction of galectin-3 levels by plasmapheresis
WO2014106803A1 (en) 2013-01-07 2014-07-10 Eliaz, Isaac Galectin-3 plasmapheresis therapy
WO2015099826A1 (en) 2013-12-27 2015-07-02 Isaac Eliaz Plasmapheresis device
US9549953B2 (en) 2011-12-08 2017-01-24 Eliaz Therapeutics, Inc. Galectin-3 plasmapheresis therapy

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593706A1 (en) * 1986-02-03 1987-08-07 Nal Transfusion Sanguine Centr Safety identification device for manual plasmapheresis

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US2689564A (en) * 1951-11-29 1954-09-21 Becton Dickinson Co Blood donor assembly
GB771968A (en) * 1954-09-20 1957-04-10 Avimo Ltd Improvements in and relating to couplings for hoses and the like
US2896619A (en) * 1954-10-14 1959-07-28 Fenwal Lab Inc Apparatus for handling fluid blood
US3145713A (en) * 1963-09-12 1964-08-25 Protein Foundation Inc Method and apparatus for processing blood
US3364930A (en) * 1965-06-11 1968-01-23 Abbott Lab Sterile venoclysis apparatus and recipient set for use therwith
US3407812A (en) * 1965-11-09 1968-10-29 Dade Reagents Inc Method for performing plasmapheresis in situ
US3523522A (en) * 1964-12-24 1970-08-11 Technicon Corp Apparatus for correlating body fluid samples with respective source individuals

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2689564A (en) * 1951-11-29 1954-09-21 Becton Dickinson Co Blood donor assembly
GB771968A (en) * 1954-09-20 1957-04-10 Avimo Ltd Improvements in and relating to couplings for hoses and the like
US2896619A (en) * 1954-10-14 1959-07-28 Fenwal Lab Inc Apparatus for handling fluid blood
US3145713A (en) * 1963-09-12 1964-08-25 Protein Foundation Inc Method and apparatus for processing blood
US3523522A (en) * 1964-12-24 1970-08-11 Technicon Corp Apparatus for correlating body fluid samples with respective source individuals
US3364930A (en) * 1965-06-11 1968-01-23 Abbott Lab Sterile venoclysis apparatus and recipient set for use therwith
US3407812A (en) * 1965-11-09 1968-10-29 Dade Reagents Inc Method for performing plasmapheresis in situ

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3945380A (en) * 1974-08-21 1976-03-23 Cutter Laboratories, Inc. Plasmapheresis assembly
US4091810A (en) * 1975-11-03 1978-05-30 Valleylab Method for intravenous feeding of a patient
US4150673A (en) * 1977-02-03 1979-04-24 Pharmachem Corporation Coded entry system for blood bag
US4547186A (en) * 1983-03-07 1985-10-15 Bartlett Robert H Autotransfusion system
US4619640A (en) * 1984-08-17 1986-10-28 Potolsky Abraham I Blood transfusion connector assembly
EP0217055A1 (en) * 1985-07-31 1987-04-08 Kawasumi Laboratories, Inc. A connector for plasmapheresis bag
US4790567A (en) * 1985-07-31 1988-12-13 Kawasumi Laboratories, Inc. Connector for plasmapheresis bag
US4655741A (en) * 1985-08-27 1987-04-07 Takeo Jyuji Blood component restoration apparatus
US4693237A (en) * 1986-01-21 1987-09-15 Hoffman Richard B Radiopaque coded ring markers for use in identifying surgical grafts
US4678458A (en) * 1986-06-09 1987-07-07 Fredeking Terry M Method for avoiding mistakes during plasmapheresis
USRE33924E (en) * 1986-07-16 1992-05-12 Autologous Blood Corp. Apparatus and method for storing and processing blood
US4804363A (en) * 1986-07-16 1989-02-14 Autologous Blood Corporation Apparatus and method for storing and processing blood
US4795434A (en) * 1987-09-10 1989-01-03 C. R. Bard, Inc. Apparatus for positioning a sensor in vivo
US5863289A (en) * 1993-09-07 1999-01-26 Hoover; Bryan Jay Cross-spike prevention system
US5725511A (en) * 1995-09-07 1998-03-10 Urrutia; Sharon A. Method and apparatus for prevention of blood-type mismatches
US9687249B2 (en) 2006-09-21 2017-06-27 Covidien Lp Safety connector assembly
US20080077063A1 (en) * 2006-09-21 2008-03-27 Tyco Healthcare Group Lp Safety Connector Apparatus
US8257286B2 (en) 2006-09-21 2012-09-04 Tyco Healthcare Group Lp Safety connector apparatus
US8287517B2 (en) 2006-09-21 2012-10-16 Tyco Healtcare Group Lp Safety connector assembly
US8257287B2 (en) 2008-03-20 2012-09-04 Tyco Healthcare Group Lp Safety connector assembly
WO2013085604A1 (en) 2011-12-08 2013-06-13 Econugenics, Inc. Reduction of galectin-3 levels by plasmapheresis
US9549953B2 (en) 2011-12-08 2017-01-24 Eliaz Therapeutics, Inc. Galectin-3 plasmapheresis therapy
EP3151009A1 (en) 2011-12-08 2017-04-05 Eliaz Therapeutics, Inc. Reduction of galectin levels by plasmapheresis
US8764695B2 (en) 2012-09-28 2014-07-01 Isaac Eliaz Reduction of galectin-3 levels by plasmapheresis
WO2014106803A1 (en) 2013-01-07 2014-07-10 Eliaz, Isaac Galectin-3 plasmapheresis therapy
WO2015099826A1 (en) 2013-12-27 2015-07-02 Isaac Eliaz Plasmapheresis device
US10953148B2 (en) 2013-12-27 2021-03-23 Eliaz Therapeutics, Inc. Plasmapheresis device

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ES381566A1 (en) 1973-09-16
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GB1290590A (en) 1972-09-27

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