US3861380A - Radioactive source projector - Google Patents

Radioactive source projector Download PDF

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US3861380A
US3861380A US300222A US30022272A US3861380A US 3861380 A US3861380 A US 3861380A US 300222 A US300222 A US 300222A US 30022272 A US30022272 A US 30022272A US 3861380 A US3861380 A US 3861380A
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Prior art keywords
source
holder
flexible
outer tube
shield block
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US300222A
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Daniel Chassagne
Gilles Delouche
Jean Fradin
Jean-Antoine Rocoplan
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ORIS INDUSTRIE SA 31-33 RUE de la FEDERATION 75752 PARIS CEDEX 15 FRANCE Cie
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Commissariat a lEnergie Atomique CEA
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Assigned to COMPAGNIE ORIS INDUSTRIE, S.A., 31-33 RUE DE LA FEDERATION, 75752 PARIS, CEDEX 15, FRANCE reassignment COMPAGNIE ORIS INDUSTRIE, S.A., 31-33 RUE DE LA FEDERATION, 75752 PARIS, CEDEX 15, FRANCE ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: COMMISSARIAT A L'ENERGIE ATOMIQUE
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21FPROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00Transportable or portable shielded containers
    • G21F5/02Transportable or portable shielded containers with provision for restricted exposure of a radiation source within the container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • A61N2005/1008Apparatus for temporary insertion of sources, e.g. afterloaders

Definitions

  • transcutaneous teleradiotherapy which has the object of sterilizing the cancerous tumor at the level of the uterine cervix and of its immediately adjacent extensions.
  • plesiocurietherapy which has the object of sterilizing the cancerous tumor at the level of the uterine cervix and of its immediately adjacent extensions.
  • This second method makes use of radioactive sources which are inserted into the vagina and the uterus and which are maintained in contact with the cancerous lesions.
  • plesiocurietherapy has made substantial strides in the field of radiation protection by virtue of the application of the so-called nonradioactive preparation technique which consists in dissociating the positioning of applicators (colpostat and probe) from the positioning of radioactive sources in these applicators.
  • the applicators are first placed in position and it is only during a second stage that the radio active sources are inserted in the applicators by means of outer tubes.
  • the present invention relates to a plesiocurietherapy apparatus or applicator which serves to apply the non radioactive preparation technique.
  • this apparatus permits accurate remote handling of radioactive sources under conditions of absolute safety; tubes in which the radioactive sources travel are light in weight, flexible, sterilizable, disposable after use and readily disconnectable after the sources have been employed on the patient.
  • the present invention relates to a polyvalent radioactive source projector for plesiocurietherapy according to the method of non-radioactive preparation for the treatment of cancerous lesions at the surface of the body or in either artificial or natural cavities (endocurietherapy) and in particular in gynecology.
  • said projector essentially comprises a projector proper as constituted by a body adapted to rest on a wheeled trolley frame and to contain a shield block which affords protection against radioactive sources and which is formed of a metal or sandwich of heavy metals having a density and an atomic number at least equal to those of lead as well as an electro-mechanical device for transferring said sources which is provided externally with a control panel attached to said body.
  • said projector essentially comprises ancillary means for displacing the sources, said ancillary means being constituted by at least four source-holders each formed of a flexible metallic spring which has contiguous turns fastened together if necessary and which is closed at one end, each source-holder being intended to be applied at one end in the vicinity of or within a cancerous tissue to be treated and being joined by means of a rapid coupling device to an actuating cable which is in turn displaced by said electromechanical transfer device and, in the case of each source-holder, a flexible outer tube which contains said source-holder and permits substantial degrees of curvature is secured by means of a screw-coupling to a flexible ejection sheath which can be joined to the projector proper; and an ancillary unit or control means operatively associated with the electromechanical transfer device for the electric and remote control of displacemnts carried out by the sourceholders from said shield block to their irradiation positions at the ends of the outer tubes and conversely for return from said outer tubes
  • FIG. 1 shows in perspective the complete projector unit together with four flexible sheaths, one of which is completed by the corresponding assembly of sourcedisplacement ancillaries;
  • FIG. 2 is an axial longitudinal sectional view showing a complete set of source-actuating ancillaries
  • FIG. 3 is a view in perspective showing the projector unit, a portion of which has been broken away in order to show the block which serves as a shield for the sources and the electromechanical device for transferring said sources;
  • FIG. 4 illustrates the control panel of said projector unit
  • FIG. 5 is a diagram which shows the mode of utilization of the apparatus according to the invention.
  • the projector unit is constituted by an outer casing or body 14 which rests on a trolley frame 1 having four wheels and contains an electromechanical transfer device 15 (See FIG. 3), devices for stopping sources in the irradiation position or storage position, and a source shield block 16 which dispenses with the need for any permanent shielding means located outside the projector unit.
  • This shield block is formed, for example, of tungsten and lead or of depleted uranium.
  • a control panel 2 which is rigidly fixed to the projector body comprises control knobs and visual indicators which are intended to carry out, respectively, the general switching-on (reference 17),checking the application of power (reference 18), checking the selection of sources (reference 19), indicating the positions of each source-holder (reference 20) as well as reading irradiation times (reference 21); an access 22 is also provided for the insertion of a resetting key.
  • FIG. 1 Since the projector is shown in FIG. 1 as comprising four source-holders, four flexible sheaths 3 can therefore pass through the side wall 4.
  • Four flaps 5 are pivotally displaceable by means of a key so that, when the apparatus is not in use, the openings 6 formed in the projector body 14 for the penetration of the sheathed cables may accordingly be closed and any displacement of the corresponding source-holders outside the shield block 16 is thereby prevented.
  • the projector unit also has four openings (not shown in the drawings) which permit the insertion of a crankhandle for the manual return of each source-holder.
  • a mechanical counter (not shown) which permits the totalization of the number of ejections is located within the projector body 14.
  • the ancillaries for the displacement of radioactive sources comprise in the case of each of the four sheaths 3:
  • a flexible source-holder 7 which can be of very small size (for example having an external diameter of 2 mm) which permits of its insertion in the uterus without preliminary anesthesia; the length of said source-holder is constant.
  • a train of radioactive sources 8 obtained by juxtaposition of unit sources such as, for example, sources of cesium-l 37 having a diameter of 1.5 mm and a total permissible activity of 650 mc.
  • An abutment member 23 has the intended function of preventing the source-holder 7 from passing beyond its correct irradiation position at the front end. This is effected by contact between member 23 and end 12 of outer tube 12.
  • the source-holder 7 may be provided if necessary with identical non-radioactive metallic balls 9.
  • An actuating cable 10 which is connected to the source-holder 7 by means of a rapid coupling device ll and carries out the displacement of the source-holder 7 by means of the electromechanical transfer device which is housed within the projector unit.
  • the cable is stored in the lower portion of the projector body, for example, on a reel or in the form of a coil.
  • a flexible outer tube 12 which permits substantial degrees of curvature (for example a radius of curvature of 15 mm).
  • This tube may be formed of a material such as nylon and may have, for example, an external diameter of 5 mm and a length of 30 cm.
  • a flexible sheath 3 which is connected to said outer tube 12 by means of a screw-coupling l3 and has a length of 2 meters.
  • the electric remote-control means 15 comprises, for example, a light signal system with one color corresponding to each position of storage, irradiation and transfer of radioactive sources from the shield block 16 (located within the interior of the projector proper) to the end of the outer tubes 12 and conversely.
  • Opening of one, two or more lateral flaps 5 results in final selection of the channels which will be utilized.
  • the projector unit is wheeled to the storage room 24 and dummy source-holders (such as nonradioactive balls, for example) are coupled to the actuating cable 10 3. Said projector unit is then wheeled to the radiographic inspection room 25 in order to check the correct operation of the apparatus before proceeding to irradiation of the patient.
  • the operations involved are identical with those which are subsequently to be carried out for the positioning of radioactive source-holders in the patient and are as fol lows: when the outer tube 12 has been inserted into the vagina the extremity of said outer tube is secured to the sheath 3 by means of the screwcoupling 13.
  • the electromechanical transfer device 15 is then actuated and causes the sourceholder 7 (which contains neutral or nonradioactive sources) to pass first out of the projector unit under the thrust exerted by the cable 10 and then into the sheath 3, then into the outer tube 12.
  • the sheath 3 has been previously extended from storage in the bottom of the projector unit via rollers 30 which direct the sheath 3 into tube 31 and then out of the casing 14 via the opening covered by flap 5.
  • the sourceholder 7 containing neutral sources is returned into the projector unit, again by means of the remote operation and control device and the outer tube 12, which remains in the vagina, is released from the sheath 3 by means of the screw-coupling l3.
  • the projector unit is returned to the storage room 24 and loaded with radioactive sources (i.e., the source-holder containing the neutral sources is disconnected from cable 13 and replaced by a new source-holder containing radioactive sources).
  • radioactive sources i.e., the source-holder containing the neutral sources is disconnected from cable 13 and replaced by a new source-holder containing radioactive sources.
  • the projector unit is then wheeled to the treatment room 26'to which the patient has been brought after radiographic examination.
  • the sheath 3, which has been extended out of the casing 14, is again attached to the outer tube 12 which has remained in the patient and the same op- 'erations as those performed at the time of radiographic inspection in the room 25 are again carried out.
  • the projector in accordance with the invention can be put to a number of uses outside the field of gynecology and that radioactive sources other than cesium-l 37 can be employed.
  • This projector permits very different periods of treatments ranging, for example, from one-quarter of an hour to eight days.
  • a further advantage is that the projector can be adapted to the majority of applicators at present in existence (for example probes and colpostats).
  • control panel 2 can operate only by means of a key which serves both to swing open the lateral flaps 5 and to switch-on the apparatus as a whole.
  • the projector according to the invention is so designed as to have a small overall size, with the result that it can readily be employed in very small rooms, as well as a light weight (less than kgs), so that the apparatus can readily be moved by one person.
  • the projector has a low exposure rate at the outer surface of its body 14, with the result that it does not require to be completed by any shielding for the purpose of maintaining the exposure rate at legally and medically permissible values.
  • All the control circuits of the electromechanical devices are supplied with direct current at low voltage (for example 24 V) in order to remove any danger of accidental electrocution.
  • the reference numeral 27 designates circuit breakers which are intended to initiate shut-down of the apparatus in the event of accidental overvoltage and the reference numeral 28 designates the control knobs of each visual signal circuit.
  • Reference numeral 30 refers to a pair of rollers for directing sheath 3 through tube 31.
  • a radioactive-source projector which comprises:
  • a moveable casing including openings
  • source-holder means in said casing and extendable through said openings, said source-holder means containing radioactive sources, and said sourceholder means including a flexible tubular element that is closed at one end and adapted to be applied to the vicinity of a cancerous tissue to be treated in a living body, and that is opened at the other end for receiving said radioactive sources;
  • flexible ejection sheath means having one end connected to said shield block means and another end connected removably to said flexible outer tube for guiding said source-holder means from said shield block means to said flexible outer tube means;
  • transfer means for transferring said actuating cable means and the associated source-holder means via said flexible ejection sheath means from said shield block means to said outer tube means and from said outer tube means to said shield block means.
  • said transfer means is an electromechanical transfer device which is electrically controlled to effect displacement of said actuating cable means and its associated sourceholder means.
  • said source-holder means is a thin elongated metallic element having an external diameter on the order of 2 8.
  • the radioactive sources contained in said source-holder means are cesium-137 sources.
  • a train of sources is housed in said source-holder means said train being formed by a plurality of unit sources having a diameter of 1.5 mm to provide a total activity of 650 10.
  • said outer flexible tube means has an external diameter on the order of 5 mm and a length on the order of 30 cm.
  • said shield block means is formed of tungsten and lead.
  • said source-holder means includes an abutment member which contacts an open end of said flexible outer tube means to prevent the source-holder means from passing beyond a correct irradiation position at the front of said open end of said flexible outer tube means.

Abstract

A radioactive source projector for the treatment of cancerous lesions, said projector comprising, on the one hand, a projector unit containing a shield block and, on the other hand, ancillary means for displacing radioactive sources, said means being constituted by source-holders formed by a flexible metallic spring and each of which is intended to be applied at one end in the vicinity of the lesions, and to be joined to an actuating cable, each source holder being contained in a flexible tube secured to a flexible ejection sheath.

Description

United States Patent [191 Chassagne et al.
[ 1 Jan. 21, 1975 I RADIOACTIVE SOURCE PROJECTOR [75] Inventors: Daniel Chassagne, Wissous; Gilles Delouche, Paris; Jean Fradin, Bois Comombes; Jean-Antoine Rocoplan, Sevres, all of France [73] Assignee: Commissariat a LEnergie Atomique, Paris, France [22] Filed: Oct. 24, 1972 21 Appl. No.: 300,222
Related U.S. Application Data [63] Continuation-impart of Ser. No. 11,226, Feb. 13,
1970, abandoned.
[30] Foreign Application Priority Data Feb. 28, 1969 France 6905574 [52] US. Cl. l28/1.2, 250/497 [51] Int. Cl A6ln 5/01 [58] Field of Search 128/1.1, 1.2; 250/363, 250/366, 369, 327, 303, 393, 497507 [56] References Cited UNITED STATES PATENTS 2,750,517 6/1956 Baum 128/1.2 X 2,798,164 7/1957 Untermeyer .1 2,862,108 11/1958 Meilink 128/12 UX 2,916,628 Prest 250/ 106 12/1959 3,147,383 9/1964 Prest 250/106 X 3,224,432 12/1965 Billingsley... 128/12 3,323,511 6/1967 Holter 128/12 3,669,093 6/1972 Sauerwein et al. 128/11 FOREIGN PATENTS OR APPLICATIONS 1,095,963 12/1960 Germany 128/11 479,311 11/1969 Switzerland 128/12 OTHER PUBLICATIONS Intern. Abstracts of Surgery, Vol. 96, No. 6, June, 1953, p. 595.
Primary Examinerl(yle L. Howell Attorney, Agent, or Firm-Craig & Antonelli [57] ABSTRACT A radioactive source projector for the treatment of cancerous lesions, said projector comprising, on the one hand, a projector unit containing a shield block and, on the other hand, ancillary means for displacing radioactive sources, said means being constituted by source-holders formed by a flexible metallic spring and each of which is intended to be applied at one end in the vicinity of the lesions, and to be joined to an actuating cable, each source holder being contained in a flexible tube secured to a flexible ejection sheath.
13 Claims, 5 Drawing Figures Pmmeu M21 1975 SHEU 1 UF 3 PATENTEU JAN 21 I875 FIGS RADIOACTIVE SOURCE PROJECTOR CROSS REFERENCE TO RELATED APPLICATION:
This application is a continuation-impart of applicants co-pending application Ser. No. 1 1,226 filed on Feb. 13, 1970, now abandoned.
The present invention relates to a radioactive source projector which is intended to be employed in plesiocurietherapy according to the method known as nonradioactive preparation for the treatment of cancerous lesions at the surface of the human body or in either artificial or natural cavities (endocurietherapy), in particular in gynecology.
It is known that, in gynecology, there are essentially two types of methods for the treatment of cancerous lesions, namely transcutaneous teleradiotherapy, whether associated with surgical methods or not, and plesiocurietherapy which has the object of sterilizing the cancerous tumor at the level of the uterine cervix and of its immediately adjacent extensions.
This second method makes use of radioactive sources which are inserted into the vagina and the uterus and which are maintained in contact with the cancerous lesions.
The majority of methods for the treatment of lesions of this type by plesiocurietherapy require the introduction of a probe in the uterus and of a colpostat in the vagina.
In the oldest methods of treatment, these two devices which are known as applicators are loaded with radioactive sources before being brought into the operating room and placed in position on the patient, and it is often difficult to protect personnel against the radioactivity of the sources all the more as the treatment which is carried out calls for the use of sources having higher activity and that a greater number of persons may come close to the patient while the sources are being placed in position and throughout the period of application.
During the last few years, plesiocurietherapy has made substantial strides in the field of radiation protection by virtue of the application of the so-called nonradioactive preparation technique which consists in dissociating the positioning of applicators (colpostat and probe) from the positioning of radioactive sources in these applicators.
In other words, the applicators are first placed in position and it is only during a second stage that the radio active sources are inserted in the applicators by means of outer tubes.
The present invention relates to a plesiocurietherapy apparatus or applicator which serves to apply the non radioactive preparation technique. In particular, this apparatus permits accurate remote handling of radioactive sources under conditions of absolute safety; tubes in which the radioactive sources travel are light in weight, flexible, sterilizable, disposable after use and readily disconnectable after the sources have been employed on the patient.
More precisely, the present invention relates to a polyvalent radioactive source projector for plesiocurietherapy according to the method of non-radioactive preparation for the treatment of cancerous lesions at the surface of the body or in either artificial or natural cavities (endocurietherapy) and in particular in gynecology. On the one hand, said projector essentially comprises a projector proper as constituted by a body adapted to rest on a wheeled trolley frame and to contain a shield block which affords protection against radioactive sources and which is formed of a metal or sandwich of heavy metals having a density and an atomic number at least equal to those of lead as well as an electro-mechanical device for transferring said sources which is provided externally with a control panel attached to said body. On the other hand, said projector essentially comprises ancillary means for displacing the sources, said ancillary means being constituted by at least four source-holders each formed of a flexible metallic spring which has contiguous turns fastened together if necessary and which is closed at one end, each source-holder being intended to be applied at one end in the vicinity of or within a cancerous tissue to be treated and being joined by means of a rapid coupling device to an actuating cable which is in turn displaced by said electromechanical transfer device and, in the case of each source-holder, a flexible outer tube which contains said source-holder and permits substantial degrees of curvature is secured by means of a screw-coupling to a flexible ejection sheath which can be joined to the projector proper; and an ancillary unit or control means operatively associated with the electromechanical transfer device for the electric and remote control of displacemnts carried out by the sourceholders from said shield block to their irradiation positions at the ends of the outer tubes and conversely for return from said outer tubes to said shield block.
Further properties and advantages of the present invention will be brought out by the following description in which one embodiment'of the device according to the invention is given by way of explanation but not in any sense by way of limitation.
Reference is made to the accompanying drawings, in which:
FIG. 1 shows in perspective the complete projector unit together with four flexible sheaths, one of which is completed by the corresponding assembly of sourcedisplacement ancillaries;
FIG. 2 is an axial longitudinal sectional view showing a complete set of source-actuating ancillaries;
FIG. 3 is a view in perspective showing the projector unit, a portion of which has been broken away in order to show the block which serves as a shield for the sources and the electromechanical device for transferring said sources;
FIG. 4 illustrates the control panel of said projector unit;
FIG. 5 is a diagram which shows the mode of utilization of the apparatus according to the invention.
The projector unit is constituted by an outer casing or body 14 which rests on a trolley frame 1 having four wheels and contains an electromechanical transfer device 15 (See FIG. 3), devices for stopping sources in the irradiation position or storage position, and a source shield block 16 which dispenses with the need for any permanent shielding means located outside the projector unit. This shield block is formed, for example, of tungsten and lead or of depleted uranium.
A control panel 2 which is rigidly fixed to the projector body comprises control knobs and visual indicators which are intended to carry out, respectively, the general switching-on (reference 17),checking the application of power (reference 18), checking the selection of sources (reference 19), indicating the positions of each source-holder (reference 20) as well as reading irradiation times (reference 21); an access 22 is also provided for the insertion of a resetting key.
Since the projector is shown in FIG. 1 as comprising four source-holders, four flexible sheaths 3 can therefore pass through the side wall 4. Four flaps 5 are pivotally displaceable by means of a key so that, when the apparatus is not in use, the openings 6 formed in the projector body 14 for the penetration of the sheathed cables may accordingly be closed and any displacement of the corresponding source-holders outside the shield block 16 is thereby prevented.
The projector unit also has four openings (not shown in the drawings) which permit the insertion of a crankhandle for the manual return of each source-holder. In addition, a mechanical counter (not shown) which permits the totalization of the number of ejections is located within the projector body 14.
The ancillaries for the displacement of radioactive sources comprise in the case of each of the four sheaths 3:
1. A flexible source-holder 7 which can be of very small size (for example having an external diameter of 2 mm) which permits of its insertion in the uterus without preliminary anesthesia; the length of said source-holder is constant. There is housed within said source-holder 7 a train of radioactive sources 8 obtained by juxtaposition of unit sources such as, for example, sources of cesium-l 37 having a diameter of 1.5 mm and a total permissible activity of 650 mc.
An abutment member 23 has the intended function of preventing the source-holder 7 from passing beyond its correct irradiation position at the front end. This is effected by contact between member 23 and end 12 of outer tube 12. The source-holder 7 may be provided if necessary with identical non-radioactive metallic balls 9.
2. An actuating cable 10 which is connected to the source-holder 7 by means of a rapid coupling device ll and carries out the displacement of the source-holder 7 by means of the electromechanical transfer device which is housed within the projector unit. (The cable is stored in the lower portion of the projector body, for example, on a reel or in the form of a coil.)
3. A flexible outer tube 12 which permits substantial degrees of curvature (for example a radius of curvature of 15 mm). This tube may be formed of a material such as nylon and may have, for example, an external diameter of 5 mm and a length of 30 cm.
4. A flexible sheath 3 which is connected to said outer tube 12 by means of a screw-coupling l3 and has a length of 2 meters.
Finally, the electric remote-control means 15 comprises, for example, a light signal system with one color corresponding to each position of storage, irradiation and transfer of radioactive sources from the shield block 16 (located within the interior of the projector proper) to the end of the outer tubes 12 and conversely.
The mode of utilization of the projector in accordance with the invention is as follows:
1. Opening of one, two or more lateral flaps 5 (carried out by the doctor by means of a control-panel key of which he is the sole possessor) results in final selection of the channels which will be utilized.
2. The projector unit is wheeled to the storage room 24 and dummy source-holders (such as nonradioactive balls, for example) are coupled to the actuating cable 10 3. Said projector unit is then wheeled to the radiographic inspection room 25 in order to check the correct operation of the apparatus before proceeding to irradiation of the patient. The operations involved are identical with those which are subsequently to be carried out for the positioning of radioactive source-holders in the patient and are as fol lows: when the outer tube 12 has been inserted into the vagina the extremity of said outer tube is secured to the sheath 3 by means of the screwcoupling 13. By use of the remote Operation control means 15', the electromechanical transfer device 15 is then actuated and causes the sourceholder 7 (which contains neutral or nonradioactive sources) to pass first out of the projector unit under the thrust exerted by the cable 10 and then into the sheath 3, then into the outer tube 12. It will be appreciated that the sheath 3 has been previously extended from storage in the bottom of the projector unit via rollers 30 which direct the sheath 3 into tube 31 and then out of the casing 14 via the opening covered by flap 5. The sourceholder 7 containing neutral sources is returned into the projector unit, again by means of the remote operation and control device and the outer tube 12, which remains in the vagina, is released from the sheath 3 by means of the screw-coupling l3.
4. The projector unit is returned to the storage room 24 and loaded with radioactive sources (i.e., the source-holder containing the neutral sources is disconnected from cable 13 and replaced by a new source-holder containing radioactive sources).
5. The projector unit is then wheeled to the treatment room 26'to which the patient has been brought after radiographic examination.
6. The sheath 3, which has been extended out of the casing 14, is again attached to the outer tube 12 which has remained in the patient and the same op- 'erations as those performed at the time of radiographic inspection in the room 25 are again carried out.
It should be noted that the projector in accordance with the invention can be put to a number of uses outside the field of gynecology and that radioactive sources other than cesium-l 37 can be employed. This projector permits very different periods of treatments ranging, for example, from one-quarter of an hour to eight days. A further advantage is that the projector can be adapted to the majority of applicators at present in existence (for example probes and colpostats).
An important feature of the apparatus lies in the fact that the control panel 2 can operate only by means of a key which serves both to swing open the lateral flaps 5 and to switch-on the apparatus as a whole.
The projector according to the invention is so designed as to have a small overall size, with the result that it can readily be employed in very small rooms, as well as a light weight (less than kgs), so that the apparatus can readily be moved by one person.
Moreover, the projector has a low exposure rate at the outer surface of its body 14, with the result that it does not require to be completed by any shielding for the purpose of maintaining the exposure rate at legally and medically permissible values.
All the control circuits of the electromechanical devices are supplied with direct current at low voltage (for example 24 V) in order to remove any danger of accidental electrocution.
On the general control panel 2, the reference numeral 27 designates circuit breakers which are intended to initiate shut-down of the apparatus in the event of accidental overvoltage and the reference numeral 28 designates the control knobs of each visual signal circuit.
Reference numeral 30 refers to a pair of rollers for directing sheath 3 through tube 31.
While the novel principles of the invention have been described, it will be understood that various omissions, modifications and changes in these principles may be made by one skilled in the art without departing from the spirit and scope of the invention.
What is claimed is:
l. A radioactive-source projector which comprises:
1. a moveable casing including openings;
2. source-holder means in said casing and extendable through said openings, said source-holder means containing radioactive sources, and said sourceholder means including a flexible tubular element that is closed at one end and adapted to be applied to the vicinity of a cancerous tissue to be treated in a living body, and that is opened at the other end for receiving said radioactive sources;
3. shield block means in said casing containing said source-holder means to afford protection against the radioactive sources positioned within said moveable casing;
4. flexible outer tube means receiving said one end of said source-holder means, said outer tube means having a small outer diameter and being adapted to be placed adjacent to the surface of a living body for treatment of cancerous tissue;
5. flexible ejection sheath means having one end connected to said shield block means and another end connected removably to said flexible outer tube for guiding said source-holder means from said shield block means to said flexible outer tube means;
6. actuating cable means removably coupled to said source-holder means for displacing said sourceholder means through said flexible ejection sheath means; and
7. transfer means for transferring said actuating cable means and the associated source-holder means via said flexible ejection sheath means from said shield block means to said outer tube means and from said outer tube means to said shield block means.
2. The projector according to claim 1, further comprising another source-holder means in said casing containing dummy non-radioactive sources adapted to be connected to said actuating cable and to be used in place of said source-holder means containing radioactive sources.
3. The projector according to claim 1, wherein a plurality of said source-holder means containing radioactive sources are provided with an equal plurality of associated flexible outer tube means, actuating cable means, flexible ejection sheath means and transfer means, each of said associated means being associated, respectively, with each of said source-holder means and with said shield block means whereby a plurality of said cancerous tissues can be treated with said projector.
4. The projector according to claim 1, wherein said transfer means is an electromechanical transfer device which is electrically controlled to effect displacement of said actuating cable means and its associated sourceholder means.
5. The projector according to claim 1, wherein said source-holder means is connected to said actuating cable means by a rapid coupling means.
6. The projector according to claim 1, wherein said flexible outer tube means is connected to said flexible ejection sheath means by a screw coupling.
7. The projector according to claim 1, wherein said source-holder means is a thin elongated metallic element having an external diameter on the order of 2 8. The projector according to claim 1, wherein the radioactive sources contained in said source-holder means are cesium-137 sources.
9. The projector according to claim 1, wherein a train of sources is housed in said source-holder means said train being formed by a plurality of unit sources having a diameter of 1.5 mm to provide a total activity of 650 10. The projector according to claim 1, wherein said outer flexible tube means has an external diameter on the order of 5 mm and a length on the order of 30 cm.
11. The projector according to claim 1, wherein said shield block means is formed of tungsten and lead.
12. The projector according to claim 1, wherein said shield block means is formed of depleted uranium.
13. The projector according to claim 1, wherein said source-holder means includes an abutment member which contacts an open end of said flexible outer tube means to prevent the source-holder means from passing beyond a correct irradiation position at the front of said open end of said flexible outer tube means.

Claims (19)

1. A radioactive-source projector which comprises: 1. a moveable casing including openings; 2. source-holder means in said casing and extendable through said openings, said source-holder meAns containing radioactive sources, and said source-holder means including a flexible tubular element that is closed at one end and adapted to be applied to the vicinity of a cancerous tissue to be treated in a living body, and that is opened at the other end for receiving said radioactive sources; 3. shield block means in said casing containing said sourceholder means to afford protection against the radioactive sources positioned within said moveable casing; 4. flexible outer tube means receiving said one end of said source-holder means, said outer tube means having a small outer diameter and being adapted to be placed adjacent to the surface of a living body for treatment of cancerous tissue; 5. flexible ejection sheath means having one end connected to said shield block means and another end connected removably to said flexible outer tube for guiding said source-holder means from said shield block means to said flexible outer tube means; 6. actuating cable means removably coupled to said sourceholder means for displacing said source-holder means through said flexible ejection sheath means; and 7. transfer means for transferring said actuating cable means and the associated source-holder means via said flexible ejection sheath means from said shield block means to said outer tube means and from said outer tube means to said shield block means.
2. source-holder means in said casing and extendable through said openings, said source-holder meAns containing radioactive sources, and said source-holder means including a flexible tubular element that is closed at one end and adapted to be applied to the vicinity of a cancerous tissue to be treated in a living body, and that is opened at the other end for receiving said radioactive sources;
2. The projector according to claim 1, further comprising another source-holder means in said casing containing dummy non-radioactive sources adapted to be connected to said actuating cable and to be used in place of said source-holder means containing radioactive sources.
3. shield block means in said casing containing said source-holder means to afford protection against the radioactive sources positioned within said moveable casing;
3. The projector according to claim 1, wherein a plurality of said source-holder means containing radioactive sources are provided with an equal plurality of associated flexible outer tube means, actuating cable means, flexible ejection sheath means and transfer means, each of said associated means being associated, respectively, with each of said source-holder means and with said shield block means whereby a plurality of said cancerous tissues can be treated with said projector.
4. The projector according to claim 1, wherein said transfer means is an electromechanical transfer device which is electrically controlled to effect displacement of said actuating cable means and its associated source-holder means.
4. flexible outer tube means receiving said one end of said source-holder means, said outer tube means having a small outer diameter and being adapted to be placed adjacent to the surface of a living body for treatment of cancerous tissue;
5. flexible ejection sheath means having one end connected to said shield block means and another end connected removably to said flexible outer tube for guiding said source-holder means from said shield block means to said flexible outer tube means;
5. The projector according to claim 1, wherein said source-holder means is connected to said actuating cable means by a rapid coupling means.
6. The projector according to claim 1, wherein said flexible outer tube means is connected to said flexible ejection sheath means by a screw coupling.
6. actuating cable means removably coupled to said source-holder means for displacing said source-holder means through said flexible ejection sheath means; and
7. transfer means for transferring said actuating cable means and the associated source-holder means via said flexible ejection sheath means from said shield block means to said outer tube means and from said outer tube means to said shield block means.
7. The projector according to claim 1, wherein said source-holder means is a thin elongated metallic element having an external diameter on the order of 2 mm.
8. The projector according to claim 1, wherein the radioactive sources contained in said source-holder means are cesium-137 sources.
9. The projector according to claim 1, wherein a train of sources is housed in said source-holder means said train being formed by a plurality of unit sources having a diameter of 1.5 mm to provide a total activity of 650 mc.
10. The projector according to claim 1, wherein said outer flexible tube means has an external diameter on the order of 5 mm and a length on the order of 30 cm.
11. The projector according to claim 1, wherein said shield block means is formed of tungsten and lead.
12. The projector according to claim 1, wherein said shield block means is formed of depleted uranium.
13. The projector according to claim 1, wherein said source-holder means includes an abutment member which contacts an open end of said flexible outer tube means to prevent the source-holder means from passing beyond a correct irradiation position at the front of said open end of said flexible outer tube means.
US300222A 1969-02-28 1972-10-24 Radioactive source projector Expired - Lifetime US3861380A (en)

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BE (1) BE746073A (en)
CH (1) CH519918A (en)
DE (1) DE2009356A1 (en)
ES (1) ES377017A1 (en)
FR (1) FR2033653A5 (en)
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EP0012004A1 (en) * 1978-11-27 1980-06-11 Tech/Ops, Inc. Apparatus for manipulating a quantity of radioactive material between a stored position and a use position
DE3335438A1 (en) * 1983-09-30 1985-04-18 Sauerwein, Kurt, Dr., 5657 Haan RADIATION TREATMENT DEVICE
DE3442762A1 (en) * 1984-11-23 1986-06-26 Anwer Dipl.-Ing. 8520 Erlangen Puthawala REMOTE CONTROLLED AFTERLOADING DEVICE FOR BRACHYCURIE THERAPY OF TUMORS
US4851694A (en) * 1987-01-28 1989-07-25 Campaignie ORIS Industrie Device for driving and positioning a source holder in an applicator used in radiotherapy
US4881938A (en) * 1984-01-12 1989-11-21 Hooft Eric T Van Method and an apparatus for treating a part of the body with radioactive material
US4881937A (en) * 1986-07-10 1989-11-21 Eric van't Hooft Method of treating a part of the body with radioactive material and a trolley for use therein
EP0366214A2 (en) * 1988-10-28 1990-05-02 Van 't Hooft, Eric Improved adaptor for remote after-loading apparatus for radiotherapy
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US5653683A (en) * 1995-02-28 1997-08-05 D'andrea; Mark A. Intracavitary catheter for use in therapeutic radiation procedures
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US6059812A (en) * 1997-03-21 2000-05-09 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
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US6146322A (en) * 1995-12-05 2000-11-14 Schneider (Europe) Ag Irradiating filament and method of making same
US6203485B1 (en) 1999-10-07 2001-03-20 Scimed Life Systems, Inc. Low attenuation guide wire for intravascular radiation delivery
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US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US20020099255A1 (en) * 1997-09-23 2002-07-25 Liprie Sam F. Afterloader apparatus
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US9717844B2 (en) 2008-06-11 2017-08-01 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US10086213B2 (en) 2015-04-23 2018-10-02 Mark A. D'Andrea Mobile gynecological balloon devices and methods
US10751432B2 (en) 2016-09-20 2020-08-25 Bracco Diagnostics Inc. Shielding assembly for a radioisotope delivery system having multiple radiation detectors
US10991474B2 (en) 2008-06-11 2021-04-27 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
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US4631415A (en) * 1983-09-30 1986-12-23 Kurt Sauerwein Radiation treatment apparatus
DE3335438A1 (en) * 1983-09-30 1985-04-18 Sauerwein, Kurt, Dr., 5657 Haan RADIATION TREATMENT DEVICE
EP0138088A1 (en) * 1983-09-30 1985-04-24 Kurt Dr. Sauerwein Radiation treatment device
US4881938A (en) * 1984-01-12 1989-11-21 Hooft Eric T Van Method and an apparatus for treating a part of the body with radioactive material
US4897076A (en) * 1984-11-23 1990-01-30 Puthawala Ajmel A Detachable and remote controllable afterloading device for radiation
EP0185939A1 (en) * 1984-11-23 1986-07-02 Anwer Dipl.-Ing. Puthawala Remotely controlled after-loading device, especially for brachycurie therapy of cancers
DE3442762A1 (en) * 1984-11-23 1986-06-26 Anwer Dipl.-Ing. 8520 Erlangen Puthawala REMOTE CONTROLLED AFTERLOADING DEVICE FOR BRACHYCURIE THERAPY OF TUMORS
US4881937A (en) * 1986-07-10 1989-11-21 Eric van't Hooft Method of treating a part of the body with radioactive material and a trolley for use therein
US4851694A (en) * 1987-01-28 1989-07-25 Campaignie ORIS Industrie Device for driving and positioning a source holder in an applicator used in radiotherapy
US5103395A (en) * 1988-10-07 1992-04-07 Spako David W System for remote positioning of a radioactive source into a patient including means for protection against improper patient exposure to radiation
EP0366214A2 (en) * 1988-10-28 1990-05-02 Van 't Hooft, Eric Improved adaptor for remote after-loading apparatus for radiotherapy
EP0366214A3 (en) * 1988-10-28 1992-02-26 Van 't Hooft, Eric Improved adaptor for remote after-loading apparatus for radiotherapy
US5092834A (en) * 1990-10-12 1992-03-03 Omnitron International, Inc. Apparatus and method for the remote handling of highly radioactive sources in the treatment of cancer
US6071227A (en) * 1993-07-01 2000-06-06 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6514191B1 (en) 1993-07-01 2003-02-04 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6074338A (en) * 1993-07-01 2000-06-13 Schneider (Europe) A.G. Medical appliances for the treatment of blood vessels by means of ionizing radiation
US6582352B2 (en) 1994-06-10 2003-06-24 Schneider (Europe) A.G. Medical appliance for treatment by ionizing radiation
US6231494B1 (en) 1994-06-10 2001-05-15 Schneider (Europe) A.G. Medical device with radiation source
US6616629B1 (en) 1994-06-24 2003-09-09 Schneider (Europe) A.G. Medical appliance with centering balloon
US5653683A (en) * 1995-02-28 1997-08-05 D'andrea; Mark A. Intracavitary catheter for use in therapeutic radiation procedures
US5720717A (en) * 1995-02-28 1998-02-24 D'andrea; Mark A. Intracavitary catheter for use in therapeutic radiation procedures
US5556401A (en) * 1995-05-23 1996-09-17 Caillouette; James C. Uterus maneuvering and associated apparatus and method, with controlled drive
US5554160A (en) * 1995-05-23 1996-09-10 Caillouette; James C. Uterus maneuvering method
US6146322A (en) * 1995-12-05 2000-11-14 Schneider (Europe) Ag Irradiating filament and method of making same
US5800333A (en) * 1996-02-20 1998-09-01 United States Surgical Corporation Afterloader provided with remote control unit
US6599230B2 (en) 1996-02-29 2003-07-29 Scimed Life Systems, Inc. Intravascular radiation delivery system
US6398708B1 (en) 1996-02-29 2002-06-04 Scimed Life Systems, Inc. Perfusion balloon and radioactive wire delivery system
US6099454A (en) * 1996-02-29 2000-08-08 Scimed Life Systems, Inc. Perfusion balloon and radioactive wire delivery system
US6234951B1 (en) 1996-02-29 2001-05-22 Scimed Life Systems, Inc. Intravascular radiation delivery system
US6110097A (en) * 1997-03-06 2000-08-29 Scimed Life Systems, Inc. Perfusion balloon catheter with radioactive source
US6117065A (en) * 1997-03-06 2000-09-12 Scimed Life Systems, Inc. Perfusion balloon catheter with radioactive source
US6676590B1 (en) 1997-03-06 2004-01-13 Scimed Life Systems, Inc. Catheter system having tubular radiation source
US6059713A (en) * 1997-03-06 2000-05-09 Scimed Life Systems, Inc. Catheter system having tubular radiation source with movable guide wire
US6635008B1 (en) 1997-03-11 2003-10-21 Interventional Therapies Llc System and method for delivering a medical treatment to a treatment site
US6059812A (en) * 1997-03-21 2000-05-09 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
US6267775B1 (en) 1997-03-21 2001-07-31 Schneider (Usa) Inc. Self-expanding medical device for centering radioactive treatment sources in body vessels
US6422989B1 (en) 1997-05-30 2002-07-23 Scimed Life Systems, Inc. Method for intravascular radioactive treatment
US6019718A (en) * 1997-05-30 2000-02-01 Scimed Life Systems, Inc. Apparatus for intravascular radioactive treatment
US20020099255A1 (en) * 1997-09-23 2002-07-25 Liprie Sam F. Afterloader apparatus
US6258019B1 (en) 1997-09-26 2001-07-10 Scimed Life Systems, Inc. Catheter for intraluminal treatment of a vessel segment with ionizing radiation
US6264596B1 (en) 1997-11-03 2001-07-24 Meadox Medicals, Inc. In-situ radioactive medical device
US6413203B1 (en) 1998-09-16 2002-07-02 Scimed Life Systems, Inc. Method and apparatus for positioning radioactive fluids within a body lumen
US6352501B1 (en) 1999-09-23 2002-03-05 Scimed Life Systems, Inc. Adjustable radiation source
US6203485B1 (en) 1999-10-07 2001-03-20 Scimed Life Systems, Inc. Low attenuation guide wire for intravascular radiation delivery
US6398709B1 (en) 1999-10-19 2002-06-04 Scimed Life Systems, Inc. Elongated member for intravascular delivery of radiation
US6416457B1 (en) 2000-03-09 2002-07-09 Scimed Life Systems, Inc. System and method for intravascular ionizing tandem radiation therapy
US6302865B1 (en) 2000-03-13 2001-10-16 Scimed Life Systems, Inc. Intravascular guidewire with perfusion lumen
US20030018232A1 (en) * 2000-06-05 2003-01-23 Mentor Corporation Automated implantation system for radioisotope seeds
US6869390B2 (en) 2000-06-05 2005-03-22 Mentor Corporation Automated implantation system for radioisotope seeds
US20050209499A1 (en) * 2000-06-05 2005-09-22 Mentor Corporation Automated implantation system for radioisotope seeds
US7959548B2 (en) 2000-06-05 2011-06-14 Core Oncology, Inc. Automated implantation system for radioisotope seeds
US20040254419A1 (en) * 2003-04-08 2004-12-16 Xingwu Wang Therapeutic assembly
US20070010702A1 (en) * 2003-04-08 2007-01-11 Xingwu Wang Medical device with low magnetic susceptibility
US9607722B2 (en) 2008-06-11 2017-03-28 Bracco Diagnostics Inc. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
US10335537B2 (en) 2008-06-11 2019-07-02 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
US9299468B2 (en) 2008-06-11 2016-03-29 Bracco Diagnostics Inc. Radioisotope generator system including activity measurement and dose calibration
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US9597053B2 (en) 2008-06-11 2017-03-21 Bracco Diagnostics Inc. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
US11464896B2 (en) 2008-06-11 2022-10-11 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
US10994072B2 (en) 2008-06-11 2021-05-04 Bracco Diagnostics Inc. Infusion system configurations
US9717844B2 (en) 2008-06-11 2017-08-01 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US9750869B2 (en) 2008-06-11 2017-09-05 Bracco Diagnostics, Inc. Integrated strontium-rubidium radioisotope infusion systems
US9750870B2 (en) 2008-06-11 2017-09-05 Bracco Diagnostics, Inc. Integrated strontium-rubidium radioisotope infusion systems
US9814826B2 (en) 2008-06-11 2017-11-14 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
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US9149653B2 (en) 2013-03-06 2015-10-06 Mark A. D'Andrea Brachytherapy devices and methods for therapeutic radiation procedures
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US10086213B2 (en) 2015-04-23 2018-10-02 Mark A. D'Andrea Mobile gynecological balloon devices and methods
US10751432B2 (en) 2016-09-20 2020-08-25 Bracco Diagnostics Inc. Shielding assembly for a radioisotope delivery system having multiple radiation detectors
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US11865298B2 (en) 2016-09-20 2024-01-09 Bracco Diagnostics Inc. Systems and techniques for generating, infusing, and controlling radioisotope delivery
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life

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Publication number Publication date
FR2033653A5 (en) 1970-12-04
DE2009356B2 (en) 1971-10-28
CH519918A (en) 1972-03-15
BE746073A (en) 1970-07-31
ES377017A1 (en) 1973-04-16
NL7002156A (en) 1970-09-01
JPS5032552B1 (en) 1975-10-22
GB1274633A (en) 1972-05-17
LU60375A1 (en) 1970-04-22
DE2009356A1 (en) 1970-09-03

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