|
| US3976764 | 11 Mar 1975 | 24 Ago 1976 | Eisai Co., Ltd. | Solid therapeutic preparation remaining in stomach |
| US4163777 | 29 Abr 1977 | 7 Ago 1979 | Lewis/Howe Company | Controlled antacid delivery form and method of treatment therewith |
| US4183898 | 25 May 1978 | 15 Ene 1980 | | Liquid base makeup composition |
| US4188188 | 27 Sep 1978 | 12 Feb 1980 | Bio-Rad Laboratories, Inc. | High density lipoprotein cholesterol assay |
| US4226849 | 14 Jun 1979 | 7 Oct 1980 | Forest Laboratories Inc. | Sustained release therapeutic compositions |
| US4259314 | 10 Dic 1979 | 31 Mar 1981 | | Method and composition for the preparation of controlled long-acting pharmaceuticals |
| US4292300 | 20 Jul 1977 | 29 Sep 1981 | Inveresk Research International | Controlled release suppositories |
| US4349535 | 11 Ene 1980 | 14 Sep 1982 | | Liquid base makeup composition |
| US4357469 | 29 Jun 1981 | 2 Nov 1982 | Forest Laboratories, Inc. | Carrier base material for prolonged release therapeutic compositions |
| US4369172 | 18 Dic 1981 | 18 Ene 1983 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| US4389393 | 26 Mar 1982 | 21 Jun 1983 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US4432975 | 19 Oct 1981 | 21 Feb 1984 | ICN Pharmaceuticals, Inc. | Process for introducing vitamin B-12 into the bloodstream |
| US4465660 | 21 Dic 1982 | 14 Ago 1984 | Mead Johnson & Company | Sustained release tablet containing at least 95 percent theophylline |
| US4529589 | 29 Sep 1983 | 16 Jul 1985 | | Pharmaceutical composition for the treatment of diabetes mellitus |
| US4540566 | 2 Abr 1984 | 10 Sep 1985 | Forest Laboratories, Inc. | Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose |
| US4547358 | 4 Jun 1984 | 15 Oct 1985 | Mead Johnson & Company | Sustained release tablet containing at least 95 percent theophylline |
| US4647599 | 9 Nov 1984 | 3 Mar 1987 | Egyt Gyogyszervegyeszeti Cyar | Sustained release pharmaceutical tablets and process for the preparation thereof |
| US4668517 | 4 Abr 1985 | 26 May 1987 | Norwich Eaton Pharmaceuticals, Inc. | Furazolidone dosage form |
| US4680323 | 1 Dic 1983 | 14 Jul 1987 | | Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration |
| US4695591 | 22 Nov 1985 | 22 Sep 1987 | Schering Corporation | Controlled release dosage forms comprising hydroxypropylmethylcellulose |
| US4713239 | 19 Nov 1985 | 15 Dic 1987 | Vsesojuny Kardiologichesky Nauchny Tsentr Adkaemii Meditsinski Nauk SSSR
Vsesojuzny Nauchno-Issledovatelsky I Ispytateiny Institut Meditsinskoi Tekhniki | Antianginal film and method of treating ischemic heart disease |
| US4764378 | 10 Feb 1986 | 16 Ago 1988 | Zetachron, Inc. | Buccal drug dosage form |
| US4775535 | 4 Abr 1986 | 4 Oct 1988 | | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4786503 | 6 Abr 1987 | 22 Nov 1988 | ALZA Corporation | Dosage form comprising parallel lamine |
| US4803079 | 20 Dic 1985 | 7 Feb 1989 | Syntex (U.S.A.) Inc. | Controlled release naproxen and naproxen sodium tablets |
| US4842854 | 13 May 1987 | 27 Jun 1989 | Vsesojuzny Kardiologichesky Nauchny Tsentr Akademii Meditsinskiki Nauk SSR | Antianginal plate for treating ischemic heart disease |
| US4851232 | 8 Jun 1987 | 25 Jul 1989 | Alza Corporation | Drug delivery system with means for obtaining desirable in vivo release rate pattern |
| US4855143 | 12 Jul 1988 | 8 Ago 1989 | | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4880830 | 9 Feb 1987 | 14 Nov 1989 | Ethical Pharmaceuticals Limited | Slow release formulation |
| US4921695 | 9 Mar 1989 | 1 May 1990 | | Antianginal plate for treating ischemic heart disease |
| US4942040 | 29 Sep 1988 | 17 Jul 1990 | Aktiebolaget Hassle | Pharmaceutical preparation and a process for its preparation |
| US4946685 | 1 Sep 1988 | 7 Ago 1990 | Alza Corporation | Cellulosic dosage form |
| US4950484 | 2 Mar 1988 | 21 Ago 1990 | Gist-Brocades N.V. | Pharmaceutical tablet, pharmaceutical granulate and process for their preparation |
| US4983398 | 15 Dic 1988 | 8 Ene 1991 | Forest Laboratories, Inc. | Sustained release drug dosage forms containing hydroxypropylmethylcellulose and alkali metal carboxylates |
| US5028633 | 21 Feb 1985 | 2 Jul 1991 | Freund Industrial Co., Ltd. | Excipient for use in compression molding and process of preparation |
| US5126145 | 11 Jun 1990 | 30 Jun 1992 | | Controlled release tablet containing water soluble medicament |
| US5204116 | 1 May 1991 | 20 Abr 1993 | Alza Corporation | Dosage form providing immediate therapy followed by prolonged therapy |
| US5268181 | 29 Jun 1992 | 7 Dic 1993 | Upsher-Smith Laboratories, Inc. | Method of using niacin to control nocturnal cholesterol synthesis |
| US5292518 | 16 Mar 1992 | 8 Mar 1994 | Hauser-Kuhrts | Prolonged-release drug tablet formulations |
| US5338550 | 21 Dic 1992 | 16 Ago 1994 | Alza Corporation | Stereoisomer therapy |
| US5393765 | 13 Dic 1993 | 28 Feb 1995 | Hoffmann-La Roche Inc. | Pharmaceutical compositions with constant erosion volume for zero order controlled release |
| US5403593 | 31 Mar 1992 | 4 Abr 1995 | Sandoz Ltd. | Melt granulated compositions for preparing sustained release dosage forms |
| US5436009 | 15 Dic 1992 | 25 Jul 1995 | Dagra Pharma B.V. | Sustained release suppositories and a process for preparation |
| US5472712 | 23 Jun 1993 | 5 Dic 1995 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| US5478572 | 6 Sep 1994 | 26 Dic 1995 | Bristol-Myers Squibb Co. | Gepirone dosage form |
| US5484607 | 13 Oct 1993 | 16 Ene 1996 | | Extended release clonidine formulation |
| US5672360 | 22 Jul 1996 | 30 Sep 1997 | Purdue Pharma, L.P. | Method of treating pain by administering 24 hour oral opioid formulations |
| US5681585 | 20 Jun 1996 | 28 Oct 1997 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5869100 | 24 Jun 1997 | 9 Feb 1999 | | Extended release clonidine formulation (tablet) |
| US5879705 | 18 Abr 1997 | 9 Mar 1999 | Euro-Celtique S.A. | Sustained release compositions of morphine and a method of preparing pharmaceutical compositions |
| US5948437 | 28 May 1997 | 7 Sep 1999 | Zeneca Limited | Pharmaceutical compositions using thiazepine |
| US5958459 | 27 Nov 1995 | 28 Sep 1999 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
| US5968551 | 27 Jul 1995 | 19 Oct 1999 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| US6010718 | 11 Abr 1997 | 4 Ene 2000 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
| US6030642 | 27 Jun 1997 | 29 Feb 2000 | | Extended release clonidine formulation (capsule) |
| US6080428 | 14 Ene 1995 | 27 Jun 2000 | | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| US6103261 | 6 Ene 1999 | 15 Ago 2000 | Purdue Pharma LP | Opioid formulations having extended controlled release |
| US6129930 | 6 Mar 1997 | 10 Oct 2000 | | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US6129933 | 24 Jul 1997 | 10 Oct 2000 | Purdue Pharma LP | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US6143322 | 8 Abr 1997 | 7 Nov 2000 | Purdue Pharma L.P. | Method of treating humans with opioid formulations having extended controlled release |
| US6143328 | 8 Mar 1999 | 7 Nov 2000 | Euro-Celtique, S.A. | Sustained release compositions and a method of preparing pharmaceutical compositions |
| US6210710 | 28 Abr 1997 | 3 Abr 2001 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
| US6242003 | 13 Abr 2000 | 5 Jun 2001 | Novartis AG | Organic compounds |
| US6264974 | 7 Jul 1998 | 24 Jul 2001 | | Buccal and sublingual administration of physostigmine |
| US6294195 | 7 Sep 1999 | 25 Sep 2001 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| US6306438 | 2 Jul 1998 | 23 Oct 2001 | Euro-Celtique, S.A. | Stabilized sustained release tramadol formulations |
| US6372252 | 28 Abr 2000 | 16 Abr 2002 | Adams Laboratories, Inc. | Guaifenesin sustained release formulation and tablets |
| US6432447 | 17 May 2001 | 13 Ago 2002 | Novartis AG | Organic compounds |
| US6551616 | 13 Oct 1999 | 22 Abr 2003 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
| US6572885 | 26 Jun 2001 | 3 Jun 2003 | Euro-Celtique, S.A. | Orally administrable opioid formulations having extended duration of effect |
| US6592901 | 15 Oct 2001 | 15 Jul 2003 | Hercules Incorporated | Highly compressible ethylcellulose for tableting |
| US6645527 | 19 Oct 2001 | 11 Nov 2003 | Euro-Celtique S.A. | Stabilized sustained release tramadol formulations |
| US6676967 | 31 Oct 1997 | 13 Ene 2004 | KOS Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
| US6733783 | 30 Oct 2001 | 11 May 2004 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| US6746691 | 31 Oct 1997 | 8 Jun 2004 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
| US6806294 | 23 Abr 2002 | 19 Oct 2004 | Euro-Celtique S.A. | Opioid analgesic |
| US6818229 | 31 Oct 1997 | 16 Nov 2004 | KOS Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
| US6872407 | 22 Nov 2002 | 29 Mar 2005 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
| US6905709 | 12 Nov 2001 | 14 Jun 2005 | Purdue Pharma, LP | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US6955821 | 15 Abr 2002 | 18 Oct 2005 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US7122204 | 21 Abr 2003 | 17 Oct 2006 | Advancis Pharmaceutical Corporation | Antibiotic composition with inhibitor |
| US7179486 | 18 May 2001 | 20 Feb 2007 | Nostrum Pharmaceuticals, Inc. | Process for preparing sustained release tablets |
| US7270831 | 20 Mar 2003 | 18 Sep 2007 | | Orally administrable opioid formulations having extended duration of effect |
| US7282221 | 14 Nov 2005 | 16 Oct 2007 | Middlebrook Pharmaceuticals, Inc. | Antiviral product, use and formulation thereof |
| US7316821 | 18 Jun 2004 | 8 Ene 2008 | Purdue Pharma, L.P. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US7476403 | 16 Jun 2004 | 13 Ene 2009 | Andrx Pharmaceuticals, LLC | Oral extended-release composition |
| US7514100 | 11 Sep 2003 | 7 Abr 2009 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| US7740881 | 24 Jul 2000 | 22 Jun 2010 | Purdue Pharma LP | Method of treating humans with opioid formulations having extended controlled release |
| US7838032 | 4 Abr 2003 | 23 Nov 2010 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
| US7884122 | 10 Nov 2009 | 8 Feb 2011 | Shionogi Pharma, Inc. | Extended release formulation and method of treating adrenergic dysregulation |
| US7943174 | 9 Jun 2004 | 17 May 2011 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| US7985420 | 4 Abr 2003 | 26 Jul 2011 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US7985421 | 22 Jun 2005 | 26 Jul 2011 | Reckitt Benckiser Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US7998506 | 23 May 2003 | 16 Ago 2011 | KOS Life Sciences, Inc. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| US8012504 | 15 Abr 2003 | 6 Sep 2011 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US8062672 | 12 Ago 2004 | 22 Nov 2011 | Shionogi Inc. | Antibiotic product, use and formulation thereof |
| US8142811 | 17 Feb 2009 | 27 Mar 2012 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| US8231898 | 28 Oct 2010 | 31 Jul 2012 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
| US8236348 | 4 Feb 2004 | 7 Ago 2012 | Bennes, Inc. | Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth |
