|Número de publicación||US3885561 A|
|Tipo de publicación||Concesión|
|Fecha de publicación||27 May 1975|
|Fecha de presentación||12 Ago 1974|
|Fecha de prioridad||15 Dic 1971|
|Número de publicación||US 3885561 A, US 3885561A, US-A-3885561, US3885561 A, US3885561A|
|Inventores||Charles N Mazal Cami|
|Cesionario original||Charles N Mazal Cami|
|Exportar cita||BiBTeX, EndNote, RefMan|
|Citas de patentes (7), Citada por (111), Clasificaciones (11)|
|Enlaces externos: USPTO, Cesión de USPTO, Espacenet|
United States Patent [1 1 Cami [451 May 27, 1975 i 1 CATHETER  Filed: Aug. 12, 1974  Appl. No.: 496,690
Related US. Application Data  Continuation-impart of Ser. No. 312,236, Dec. 4,
 US. Cl 128/214; 128/2 R; 128/348 R; 128/350 V  Int. Cl... A6lm 5/00; A6lb 25/00; A6lb 27/00  Field of Search 128/214, 2 R, 2 B, 130, 128/224, 348, 349 R, 349 B, 349 BV, 350 R, 350 V  References Cited UNITED STATES PATENTS 2,969,066 1/1961 Holteret al 128/350 v 3,020,913 2/1962 Heyer 128/350 V 3,086,525 4/1963 Whitcomb 128/232 3,483,859 12/1969 Pittman 128/2 R 3,485,234 12/1969 Stevens 128/348 X Sheridan 128/348 Dalton 128/2 R Primary Examiner-Aldrich F. Medbery Attorney, Agent, or Firm-Ladas, Parry, Von Gehr, Goldsmith & Deschamps  ABSTRACT A catheter for epidural anesthesia comprising a plastic tube which has its near end open permitting adaptation to the tip of syringe or the like, and the opposite or distal end rounded and carrying embedded in the interior of same a metallic piece opaque to X-rays; having in the distal end, which is closed, from two to six longitudinal slits, each of which is both longitudinally and circumferentially offset from the nearest adjacent slit so that the diametral planes in which said slits are placed form a dihedral angle of at least 45, and furthermore by the fact that none of the diametral planes in which each slit is located has more than one slit, thus affording the catheter practically the same rigidity as that of a catheter having no slit whatever.
3 Claims, 3 Drawing Figures CATHETER CROSS REFERENCE TO RELATED APPLICATIONS This application is a continuation-in part of my copending application Ser. No. 312,236, filed Dec. 4, I972, and now abandoned, for Catheter.
BACKGROUND OF THE INVENTION In recent years the technique of administering anesthetics in liquid form directly into the spinal column, specifically into the peridural space, has been improved, achieving benefits in comparison to general anesthesia of the patient, and particularly to that accomplished be means of anesthetic gases, in cases of sur' gery particularly of the lower abdomen and the legs, because the sensibility of the patient is successfully isolated in these areas without loss of consciousness, and without saturating the blood stream with anesthetic solutions.
Epidural anesthesia has also proved advantageous in childbirth, whether or not controlled by the introduction of ocitosics.
To administer this anesthesia it was at first necessary to insert a special needle into the resistant external tissues, between the vertebrae and through the softer and extremely delicate internal tissues before achieving penetration into the epidural space.
At first the anesthetic was administered directly through the needle, with the corresponding danger which a sharp pointed instrument of this character represents in such a critical spot.
Later on it became preferable to effect the operation by means of introducing a flexible tube of thermoplastic material of a diameter which could be passed through the inside of the needle which had been in serted into the body by direct puncture or by incision, permitting thereafter the extraction of the needle sliding over the tube when the latter had been placed in the desired location; this is tested by extracting through the tube a biological liquid sample. The tube of the first catheter had both ends cut square, and on one end it included a small adapter so that once the needle was withdrawn, a syringe with anesthetic could be attached.
Notwithstanding the advantages of the flexible catheter with square cut ends, over the administration of anesthetics by a simple needle, the edges of the square cut of the tube produce trauma in the delicate tissues through which the catheter passes and cause postoperatory pain to the patient; in addition, since the said catheter has no penetration markings, it is difficult to know to what depth the tube had been inserted.
Furthermore, with this tube the exact location of same in the epidural space is unknown, since the thermoplastic material of which it is made cannot be detected with X-rays.
Another problem caused by this catheter with square cut ends is that the orifice in the end of the tube frequently becomes blocked, since it is precisely the end, thereof that is used to achieve penetration, and hence in the opening of the tube tiny clots, fibers and particles of the tissue itself are deposited, obstructing the passage of the anesthetic liquid.
Subsequently, in order to avoid the foregoing problems, a catheter was developed which had the penetration tip at its distal end rounded to a bullet shape to reduce the trauma of adjacent tissues and to facilitate penetration through them.
The orifices for supplying the anesthetic in said catheter consisted of two practically circular lateral apertures near the distal end, diametrically opposite each other, and slightlyseparated from each other in respect to the lengthwise axis of the catheter.
Furthermore, in this catheter or probe indelible markings were provided separated by a certain interval, with the object of determining the penetration of the catheter.
Notwithstanding the progress achieved with this catheter, the shape and location of the lateral orifices seriously affected the strength of the tube, and weakened it, since the catheter in its penetration travel generally bends principally at the said orifices, causing serious complications such as the obstruction of the flow of the anesthetic liquid, difficulty in the withdrawal of the catheter when the bend is very pronounced, and occasionally the tip of the catheter comes off; obviously it is more difficult to accomplish penetration of the catheter under such conditions.
In addition to the problems mentioned with each of the catheters individually cited, they all uniformly have the drawback that, since within the epidural space there is a higher pressure than atmospheric pressure, the cephalorachidian liquid tends to escape through the catheter in cases where accidentally or intentionally the syringe is disconnected from the adapter or the latter from the catheter, thus producing a loss of the cited liquid with corresponding serious results.
In some catheters, in order to determine their position within the human body, heavy metals have been mixed with the plastic material; while this does produce a certain opacity which can be detected by X-rays, it is not very precise, since the epidural space into which the catheter is to penetrate is surrounded by bone tissue.
The above references are the best known in the field of catheters for epidural anesthesia; however, outside of this field, and for the sole purpose of differentiating them from the present invention, drain tubes or shunts operating on differential pressure may be mentioned; they are placed in the body permanently or for prolonged periods; some of them are for draining cerebrospinal fluid to either the atrium or the peritoneum. Since the pressure in the atrium is greater than the pressure in the cerebroventricular space, the drain tube has been provided with valving cuts at one of its ends, so as to prevent the back-flow of blood toward the ventricle; at its other end the drain tube has circular perforations; some of these tubes have as a backing member an inner concentric cylindrical body near the cuts to prevent the latter from becoming blocked; the arrangement of the cuts has not been made in these shunts specifically to give the tube strength, and furthermore, one of their ends generally carries circular perforations. Obviously, both the structural elements of these pressure shunts and their application are outside of the field of catheters for supplying epidural anesthesia of the present invention.
SUMMARY OF THE INVENTION In view of the foregoing it is one object of the present invention to provide a catheter for epidural anesthesia which has its distal end rounded to prevent damage to the adjacent tissues during its penetration, thereof, and
which has embedded in the material of this distal end a piece of wire which is inert to biological tissue, which does not effect an ion interchange with biological fluids or tissue, and which may be stainless steel, with a low content of carbon, gold, platinum, alloys of cobalt, chrome and molybdenum, etc, and which is clearly detectable by X-rays even when the catheter is surrounded by bone tissue; and having penetration interval markings which will allow the user to determine the exact location of its application,
Another object of this invention is to provide a catheter having near its distal end a plurality of longitudinal radial slits to dispense the anesthetic which open only when a syringe or the like attached to the near end of the catheter develops a greater positive pressure than that prevailing in the cavity in which the anesthetic is to be delivered, or otherwise, when the syringe exerts a negative pressure or suction such that the slits open permitting the withdrawal of a sample of the biological liquid in order to determine the location of the catheter.
Each one of said radial slits is both longitudinally and circunferentially offset from the nearest slit so that no single diametral plane has more than one slit and the dihedral angle between diametral planes carrying adjacent slits is at least 45, whereby the catheter is given the same rigidity as if it had no slits, enabling it to make easy penetration without the problems aforementioned due to bending of same.
These and other objects to be obtained through the use of this invention will be better understood and more fully perceived in the following description which refers to the attached drawings of the preferred embodiment of the invention.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1, is an elevational view showing the catheter of the present invention cut into sections and attached to an adapter at its near end, which is in turn coupled to the tip of a hypodermic syringe.
FIG. 2, is a detail view of the distal end of the catheter of the present invention, showing the longitudinal slits to deliver anesthetic, disposed in different diametral planes and in a conventional section showing the piece of metallic wire embedded in the inside of the distal end, which is easily detectable with X-rays.
FIG. 3, is a cross-sectional view along 3-3 of FIG. 2.
DETAILED DESCRIPTION OF THE INVENTION The improved catheter 11 of the present invention, is composed of a tube 12 of thermoplastic material having a rounded distal end 13, bullet shaped to facilitate its penetration through adjacent tissues until it reaches the epidural space, and having its near end 14 so made as to permit the attachement of an adapter 15 which in turn can be attached to a hypodermic syringe 16 partially shown, by means of which a positive pressure is applied to the anesthetic contained therein, causing it to pass through the length of tube 12 and discharging it in the epidural space through certain longitudinal slits 17 placed radially in relation to the longitudinal axis of tube 12 and so disposed in diametral planes that the dihedral angle formed between the diametral planes of two adjacent slits is at least 45 and that furthermore, none of the said diametral planes contains more than a single slit 17, thus giving the catheter the same rigidity as if it had no slit whatever, to permit its ready penetration without the danger of bending or breaking.
The catheter 11 of the present invention further has embedded in the distal end 13, thereof as shown in FIG. 2 a piece of metallic wire 18 which is inert to biological tissues and which does not engage in ion exchange with the biological liquids and tissues, being of such a material as stainless steel with low content of carbon, platinum, gold. alloys of cobalt, chrome and molybdenum, etc., said metallic portion 18 being readily detectable by means of X-rays even when catheter 11 is surrounded by bone tissue, as is usual in cases of epidural anesthesia.
The tube 12 also includes markings 19, 20, 21, which are different from one onother and spaced along the catheter to show the person applying the anesthesia the location and penetration of the catheter and of the slits for delivering anesthetic. This indication can be further made more precise by means of X-rays, thereby detecting the position of metallic portion 18.
Once the slots 17 for delivering anesthetic are in the intended epidural space a negative pressure is applied with the syringe 16 withdrawing a sample of the biological liquid and when the source of the latter has been determined a positive pressure is applied upon the anesthetic, delivering it through slits 17 into the epidural space.
The initial penetration of the catheter 11 is carried out as described at the beginning by passing it slidingly through a hypodermic needle, which is done by marking a prior incision or puncture in the external tissues of the patient, and later withdrawing this placement needle once the catheter 11 has been situated in the desired location.
It is important to note that the opening of slits 17, is effected solely by the application of a positive or negative pressure, thus preventing the back-flow of fluid through a mere pressure difference due to carelessness with the resulting complications and problems.
While, the foregoing description has been drawn to a specific embodiment of the invention, it will be understood by all those skilled in the subject matter that changes in form and detail are encompassed withing the scope and spirit of the invention.
1. A catheter for epidural anesthesia composed of a plastic material having its near end open and adapted for connection to a syringe and having its distal end closed androunded and having embedded in its internal portion a metallic piece which is opaque to X-rays, said catheter having near its distal end a plurality of longitudinal slits for delivering anesthetic, each of said slits being both longitudinally and circunferentially offset from the nearest slit so that each slit be placed in a different diametral plane, and being so spaced from the adjacent slit that the diametral planes on which they are located form an angle of at least 45, thus giving the catheter substantially equal rigidity to that of a catheter having no slit whatever.
2. The catheter for epidural anesthesia as described in claim 1, wherein the slits for delivering anestesic consist of from two to six slits longitudinally spaced from each other.
3. The catheter for epidural anesthesia as described in claim 1, wherein the metallic portion for detection by X-rays embedded within the distal end of the catheter is a piece of cylindrical wire which is inert to biological tissues and does not engage in ion exchange with the biological liquids and tissues.
UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION Patent No. 3,885,561 Dated May 27, 1975 I Charles N. MAZAL-CAMI It is certified that error appears in the above-identified patent and that said Letters Patent are hereby corrected as shown below:
On the cover sheet, left column, the inventor s last name "Mazal Cami" should read-- Mazal-Cami.
On the cover sheet, left column, below " Appl. No.: 496,690" should be added  Foreign Application Priority Data December 15, 1971 Mexico ..l32,l27.
Signed and gcaled this twenty-third D 3)! Of September I 975 [SEAL] Arrest:
RUTH C. MASON C. MARSHALL DANN .-lrt(sling ()ffiver (nmmmsimu'r nj'larcnls and Trademarks
|Patente citada||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US2969066 *||2 Oct 1956||24 Ene 1961||Holter Company||Device for draining ventricular fluid in cases of hydrocephalus|
|US3020913 *||15 Jul 1958||13 Feb 1962||William T Heyer||Surgical drain|
|US3086525 *||21 Abr 1961||23 Abr 1963||Whitcomb John G||Device for intra-cavitary infusion of local anesthetic agent or other medicinal solutions|
|US3483859 *||29 Nov 1967||16 Dic 1969||Pittman Fred E||String for marking bleeding in upper gastro-intestinal tract|
|US3485234 *||13 Abr 1966||23 Dic 1969||Cordis Corp||Tubular products and method of making same|
|US3599641 *||13 Mar 1970||17 Ago 1971||Sheridan David S||Combination connector and channel closure system for catheters|
|US3838681 *||29 Dic 1972||1 Oct 1974||Dalton J||Device for collection of cells from the vagina|
|Patente citante||Fecha de presentación||Fecha de publicación||Solicitante||Título|
|US4160454 *||14 Feb 1977||10 Jul 1979||University Of Utah||Implantable catheter system|
|US4182326 *||26 Ago 1977||8 Ene 1980||Ims Limited||Laryngotracheal syringe|
|US4240434 *||10 Oct 1978||23 Dic 1980||Newkirk John B||Peritoneo-venous shunt|
|US4282875 *||24 Ene 1979||11 Ago 1981||Serbinenko Fedor A||Occlusive device|
|US4317452 *||4 Feb 1980||2 Mar 1982||C. R. Bard, Inc.||Body fluid drain|
|US4327722 *||20 Ago 1979||4 May 1982||Groshong Leroy E||Methods and apparatus for intravenous therapy and hyperalimentation|
|US4384584 *||28 Oct 1981||24 May 1983||Chen Allen S||Method and means for esophageal feeding|
|US4405308 *||23 Dic 1981||20 Sep 1983||The Kendall Company||Anesthesia device with selective spray ports|
|US4410320 *||28 Ago 1981||18 Oct 1983||Ethox Corp.||Weighted enteric feeding tube|
|US4431426 *||3 Oct 1980||14 Feb 1984||Groshong Leroy E||Methods and apparatus for intravenous therapy and hyperalimentation|
|US4465068 *||2 Jul 1982||14 Ago 1984||The United States Of America As Represented By The Secretary Of The Air Force||Metallic aid and technique in fitting voice prosthesis|
|US4549879 *||3 May 1983||29 Oct 1985||Catheter Technology Corporation||Valved two-way catheter|
|US4586921 *||17 Ago 1983||6 May 1986||Daniel Berson||Method of applying a local anesthetic agent to a wound|
|US4639246 *||9 Sep 1985||27 Ene 1987||Animal Healthcare Products||Catheter|
|US4657536 *||19 Mar 1981||14 Abr 1987||Regents Of The University Of Minnesota||Check valve catheter|
|US4671796 *||25 Oct 1985||9 Jun 1987||Catheter Technology Corp.||Valved two-way catheter|
|US4701166 *||2 Oct 1986||20 Oct 1987||Catheter Technology Corp.||Valved two-way catheter|
|US4704111 *||20 Nov 1985||3 Nov 1987||Moss James P||Nasogastric feeding tube|
|US4747840 *||17 Sep 1986||31 May 1988||Ladika Joseph E||Selective pulmonary arteriograph catheter|
|US4753640 *||6 Oct 1986||28 Jun 1988||Catheter Technology Corporation||Catheters and methods|
|US4773430 *||6 Ene 1986||27 Sep 1988||Yissim Research Development Company||Method and apparatus for the localization of bleeding in the gastrointestinal tract|
|US4781682 *||13 Ago 1987||1 Nov 1988||Patel Piyush V||Catheter having support flaps and method of inserting catheter|
|US4784638 *||17 Sep 1987||15 Nov 1988||Neurodynamics, Inc.||Angled hole ventricular catheter and method of making same|
|US4838879 *||1 May 1987||13 Jun 1989||Terumo Kabushiki Kaisha||Catheter|
|US4951686 *||3 Abr 1989||28 Ago 1990||B. Braun-Ssc Ag||Color marks on catheter guide wire|
|US4967743 *||1 Dic 1988||6 Nov 1990||Ballard Medical Products||Neonatal closed system for involuntary aspiration and ventilation, and method|
|US4989608 *||28 Abr 1989||5 Feb 1991||Ratner Adam V||Device construction and method facilitating magnetic resonance imaging of foreign objects in a body|
|US4995863 *||25 Feb 1988||26 Feb 1991||Catheter Technology Corporation||Catheter with slit valve|
|US5065754 *||6 Jun 1990||19 Nov 1991||Ballard Medical Products||Aspirating catheter tube inserter|
|US5107829 *||25 Abr 1990||28 Abr 1992||Ballard Medical Products||Neonatal closed system for involuntary aspiration and ventilation, and method|
|US5133345 *||14 Nov 1991||28 Jul 1992||Ballard Medical Products||Neonatal closed system for involuntary aspiration and ventilation, and method|
|US5147318 *||4 Mar 1991||15 Sep 1992||Board Of Regents, The University Of Texas System||Valved arterial catheter|
|US5147332 *||17 May 1991||15 Sep 1992||C.R. Bard, Inc.||Multi-valve catheter for improved reliability|
|US5160325 *||22 Ene 1991||3 Nov 1992||C. R. Bard, Inc.||Catheter with novel lumens shapes|
|US5169393 *||15 Oct 1991||8 Dic 1992||Robert Moorehead||Two-way outdwelling slit valving of medical liquid flow through a cannula and methods|
|US5180387 *||2 Nov 1988||19 Ene 1993||Neurodynamics, Inc.||Angled hole ventricular catheter with non-circular bore|
|US5201722 *||4 Sep 1990||13 Abr 1993||Moorehead Robert H||Two-way outdwelling slit valving of medical liquid flow through a cannula and methods|
|US5203777 *||19 Mar 1992||20 Abr 1993||Lee Peter Y||Radiopaque marker system for a tubular device|
|US5205834 *||24 Jun 1992||27 Abr 1993||Moorehead H Robert||Two-way outdwelling slit valving of medical liquid flow through a cannula and methods|
|US5215522 *||5 Abr 1991||1 Jun 1993||Ballard Medical Products||Single use medical aspirating device and method|
|US5215527 *||12 Dic 1991||1 Jun 1993||Becton, Dickinson And Company||Catheter introducer assembly|
|US5250034 *||7 Ago 1991||5 Oct 1993||E-Z-Em, Inc.||Pressure responsive valve catheter|
|US5261885 *||14 Jul 1992||16 Nov 1993||Cook Pacemaker Corporation||Valved catheter|
|US5277177 *||16 Jul 1991||11 Ene 1994||Ballard Medical Products||Single use medical aspirating device and method|
|US5314418 *||9 Sep 1993||24 May 1994||Toyo Boseki Kabushiki Kaisha||Cannula|
|US5324261 *||11 Dic 1992||28 Jun 1994||Medtronic, Inc.||Drug delivery balloon catheter with line of weakness|
|US5370614 *||19 Nov 1993||6 Dic 1994||Medtronic, Inc.||Method for making a drug delivery balloon catheter|
|US5423764 *||14 Jun 1993||13 Jun 1995||Fry; William A.||Lavage apparatus|
|US5611336 *||30 Mar 1995||18 Mar 1997||Ballard Medical Products, Inc.||Single use medical aspirating device and method|
|US5645065 *||11 Abr 1995||8 Jul 1997||Navion Biomedical Corporation||Catheter depth, position and orientation location system|
|US5664567 *||16 Jul 1996||9 Sep 1997||Linder; Gerald S.||Fenestrated nasopharyngeal airway for drainage|
|US5694922 *||19 Ago 1994||9 Dic 1997||Ballard Medical Products||Swivel tube connections with hermetic seals|
|US5735271 *||22 May 1996||7 Abr 1998||Ballard Medical Products||Multiple access adaptors for monitoring, sampling, medicating, aspirating, and ventilating the respiratory tract of a patient|
|US5807349 *||10 Mar 1997||15 Sep 1998||United States Surgical Corporation||Catheter having valve mechanism|
|US5893840 *||24 Abr 1996||13 Abr 1999||Medtronic, Inc.||Releasable microcapsules on balloon catheters|
|US5928203 *||1 Oct 1997||27 Jul 1999||Boston Scientific Corporation||Medical fluid infusion and aspiration|
|US6085769 *||24 Feb 1998||11 Jul 2000||Northern Telecom Limited||Telecommunications electronics enclosure drain valve|
|US6120483 *||19 Mar 1999||19 Sep 2000||Boston Scientific Corporation||Medical fluid infusion and aspiration|
|US6170137 *||3 Sep 1998||9 Ene 2001||Mcintire Jerald R.||Embalming fluid distribution tube|
|US6436071||8 Jun 1999||20 Ago 2002||The Trustees Of Columbia University In The City Of New York||Intravascular systems for corporeal cooling|
|US6436077||7 Ago 2000||20 Ago 2002||Boston Scientific Corporation||Medical fluid infusion and aspiration|
|US6494203||12 Nov 1999||17 Dic 2002||Ballard Medical Products||Medical aspirating/ventilating closed system improvements and methods|
|US6605106||26 Ene 2001||12 Ago 2003||The Trustees Of Columbia University In The City Of New York||Intravascular systems for corporeal cooling|
|US6612304||5 Oct 2000||2 Sep 2003||Kimberly-Clark Worldwide, Inc.||Respiratory care multiple access port assembly and adapter|
|US6723075||1 Jul 2002||20 Abr 2004||Christopher T. Davey||Medical fluid infusion and aspiration|
|US6796976||5 Mar 1999||28 Sep 2004||Scimed Life Systems, Inc.||Establishing access to the body|
|US7192404 *||12 Dic 2001||20 Mar 2007||Ethicon Endo-Surgery, Inc.||MRI compatible surgical biopsy device having a tip which leaves an artifact|
|US7452351||16 Abr 2004||18 Nov 2008||Kyphon Sarl||Spinal diagnostic methods and apparatus|
|US7601138 *||18 Jun 2002||13 Oct 2009||B. Braun Melsungen Ag||Catheter|
|US7678100||27 Sep 2004||16 Mar 2010||Boston Scientific Scimed, Inc.||Apparatus for establishing access to the body|
|US7704220||25 Ene 2006||27 Abr 2010||Thermopeutix, Inc.||Systems and methods for selective thermal treatment|
|US7763196||19 Oct 2007||27 Jul 2010||B. Braun Melsungen Ag||Catheter|
|US7789846||25 Ene 2005||7 Sep 2010||Thermopeutix, Inc.||System and methods for selective thermal treatment|
|US7824390||26 Dic 2006||2 Nov 2010||Kyphon SÀRL||Spinal diagnostic methods and apparatus|
|US7905874||26 Dic 2006||15 Mar 2011||Kyphon Sarl||Spinal diagnostic methods and apparatus|
|US7955312||26 Dic 2006||7 Jun 2011||Kyphon Sarl||Spinal diagnostic methods and apparatus|
|US8157786||26 Dic 2006||17 Abr 2012||Kyphon Sarl||Spinal diagnostic methods and apparatus|
|US8702744 *||9 May 2005||22 Abr 2014||Nexeon Medsystems, Inc.||Apparatus and methods for renal stenting|
|US9447892||3 Ago 2012||20 Sep 2016||Angiodynamics, Inc.||Pressure activated valve for high flow rate and pressure venous access applications|
|US20030018317 *||18 Jun 2002||23 Ene 2003||Udo Goebel||Catheter|
|US20030109801 *||12 Dic 2001||12 Jun 2003||Rhad Edward A.||MRI compatible surgical biopsy device having a tip which leaves an artifact|
|US20050043703 *||21 Ago 2003||24 Feb 2005||Greg Nordgren||Slit valves for catheter tips and methods|
|US20050049570 *||27 Sep 2004||3 Mar 2005||Yem Chin||Apparatus and method for establishing access to the body|
|US20050234425 *||16 Abr 2004||20 Oct 2005||Innospine, Inc.||Spinal diagnostic methods and apparatus|
|US20060036303 *||17 Oct 2005||16 Feb 2006||Schwartz Arthur E||Intravascular systems for corporeal cooling|
|US20060167398 *||25 Ene 2005||27 Jul 2006||Thermopeutix Inc.||System and methods for selective thermal treatment|
|US20060167399 *||25 Ene 2006||27 Jul 2006||Solar Ronald J||Systems and methods for selective thermal treatment|
|US20060253186 *||9 May 2005||9 Nov 2006||Paragon Intellectual Properties, Llc||Apparatus and methods for renal stenting|
|US20080021435 *||26 Dic 2006||24 Ene 2008||Kyphon, Inc.||Spinal diagnostic methods and apparatus|
|US20080045927 *||19 Oct 2007||21 Feb 2008||B. Braun Melsungen Ag||Catheter|
|US20080077117 *||26 Dic 2006||27 Mar 2008||Kyphon, Inc.||Spinal diagnostic methods and apparatus|
|US20080077172 *||26 Dic 2006||27 Mar 2008||Kyphon, Inc.||Spinal diagnostic methods and apparatus|
|US20110172542 *||10 Ene 2011||14 Jul 2011||Custom Medical Applications, Inc.||Ultrasound guided echogenic catheter and related methods|
|US20130267928 *||14 Mar 2013||10 Oct 2013||Incube, LLC||Apparatus, systems and methods for delivery of medication to the brain to treat neurological conditions|
|US20130274600 *||13 Mar 2013||17 Oct 2013||Acclarent, Inc.||Devices and Method for Maxillary Sinus Lavage|
|US20130317410 *||23 May 2012||28 Nov 2013||Codman & Shurtleff, Inc.||Catheter curvature braces and methods of using same|
|US20140054189 *||23 Ago 2012||27 Feb 2014||Lih-Chiu Wu||Nasal flushing device|
|DE3636806A1 *||29 Oct 1986||7 May 1987||Smiths Industries Plc||Catheter and method of producing it|
|DE3636806C2 *||29 Oct 1986||19 Feb 1998||Smiths Industries Plc||Katheter und Verfahren zu seiner Herstellung|
|EP0052841A1 *||13 Nov 1981||2 Jun 1982||Intermedicat Gmbh||Central venous catheter|
|EP0125844A2 *||3 May 1984||21 Nov 1984||Catheter Technology Corporation||Valved two-way catheter|
|EP0125844A3 *||3 May 1984||30 Oct 1985||Catheter Technology Corporation||Valved two-way catheter|
|EP0318918A2 *||29 Nov 1988||7 Jun 1989||Terumo Kabushiki Kaisha||Balloon cathether|
|EP0318918A3 *||29 Nov 1988||13 Dic 1989||Terumo Kabushiki Kaisha||Balloon cathether|
|EP0346012A1 *||2 Jun 1989||13 Dic 1989||Sherwood Medical Company||Angiographic catheter|
|EP0693300A3 *||12 Jun 1995||26 Mar 1997||Minimed Inc||Side slit catheter|
|EP0728495A2 *||14 Dic 1995||28 Ago 1996||Len Edwards Scrymgeour Carrie||Epidural catheter|
|EP0728495A3 *||14 Dic 1995||28 Abr 1999||Len Edwards Scrymgeour Carrie||Epidural catheter|
|WO1980002230A1 *||10 Abr 1980||30 Oct 1980||Univ Minnesota||Check valve catheter|
|WO1989002290A1 *||7 Sep 1988||23 Mar 1989||Neurodynamics, Inc.||Angled hole ventricular catheter|
|WO1993004721A1 *||25 Ago 1992||18 Mar 1993||Medimex Holfeld Gmbh & Co.||Tubular catheter for epidural anesthesia|
|Clasificación de EE.UU.||604/247, 137/848, 604/523, 137/493|
|Clasificación internacional||A61M25/00, A61M25/01|
|Clasificación cooperativa||A61M2025/0007, A61M25/0108, A61M25/007|
|Clasificación europea||A61M25/00T10C, A61M25/01C1|