US3888249A - Arterial infusion catheter - Google Patents

Arterial infusion catheter Download PDF

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US3888249A
US3888249A US412199A US41219973A US3888249A US 3888249 A US3888249 A US 3888249A US 412199 A US412199 A US 412199A US 41219973 A US41219973 A US 41219973A US 3888249 A US3888249 A US 3888249A
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cannula
catheter
distal end
cutout portions
medication
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David L Spencer
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M25/0075—Valve means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M25/0075—Valve means
    • A61M2025/0076—Unidirectional valves

Definitions

  • a catheter for prolonged mfuslon of medlcatlon into 350 v 35' 274 an artery has a unique tip design employing the flap valve principle to assure uniform and [56] References Cited steady diffusion of the medication into the bloodstream and also to inhibit retrograde flow of blood UNITED STATES PATENTS into the catheter thereby minimizing clotting and the 28/348 X resulting blockage of the medication flow eyer t.
  • catheters of various types are used to carry out the necessary treatments. Some catheters are used for drainage, some for infusion and some for both purposes. Also, depending upon the particular treatment, the catheters may be used for either short term or prolonged treatment. In the area of regional intra-arterial infusion, catheters are used to inject or infuse medication into the bloodstream. For example, in certain malignant tumors, arterial catheters are used for the regional infusion of chemotheraputic agents over prolonged periods.
  • the catheter once the catheter has been inserted, it can be fixed in place and utilized for continuous infusion or for periodic infusion over prolonged periods. In this manner, the trauma of repeated punctures and re-insertions of the catheter can be kept to a mini mum.
  • several difficulties are encountered. Quite frequently, the blood will clot around the distal end of the catheter and cause premature cessation of the treatment.
  • there is an inadequate mixing of the medication with the bloodstream which results in sporadic and unpredictable drug levels at the sight of the lesion. When clotting around the end of the catheter occurs resulting in blockage of the flow of medication, the catheter must be withdrawn, cleaned and reinserted.
  • the invention provides a catheter design in which the distal end inserted into the artery is provided with a flexible portion containing one or more slits which serve as valves.
  • the slits When positive pressure is applied to start the infusion process, the slits will open and allow the medication to enter the arterial flow of blood.
  • clotting cannot occur to block the flow, and if the positive pressure is withdrawn the slits will close to shut off the flow of medication and inhibit the retrograde flow of blood into the catheter thereby preventing blockage of the catheter.
  • greatly improved diffusion of the medication into the bloodstream is achieved.
  • FIG. 1 is a view of a portion of an artery, partly in section, and showing a catheter employing the principles of the invention in place in the artery;
  • FIG. 2 is a perspective view of the end of the catheter and showing the valves in a closed position
  • FIG. 3 is a sectional view taken on line 33 of FIG.
  • FIG. 4 is a perspective view similar to FIG. 2 but showing the valves in an open position
  • FIG. 5 is a sectional view taken on the line S5 of FIG. 4;
  • FIG. 6 is a perspective view showing the tip of a catheter employing the principles of the invention as disclosed in another embodiment thereof.
  • FIG. 7 is a view similar to FIG. 6 but showing the valves of the catheter of the second embodiment in an open position.
  • FIG. 1 there is shown in section the wall 10 of an artery 12 in which the flow of blood is in the direction indicated by the arrows.
  • the artery in punctured by a suitable instrument (not shown) and then the tip of a catheter 14 is inserted to the desired depth and with its distal end 16 pointing downstream.
  • the catheter 14 consists of a cannula or hollow tube 18 the proximal end 19 of which is attached to a source of medication (not shown). By force of gravity or other means of applying a positive pressure, the medication flows through the tube 18 and is discharged through the distal end 16 into the bloodstream.
  • the tube 18 is provided with a plurality of cutout portions or windows 20 which are formed in between connecting ribs 22 that interconnect the tube I8 and the distal end 16 of the catheter I4.
  • Each of the windows 20 is covered with a material having a modulus of elasticity less than the material from which the tube 18 is made.
  • Formed in the material covering each of the windows 20 is a plurality of cuts or slits 24 which provide valves through which fluid introduced into the catheter I4 may be discharged.
  • the valves 24 will be closed thus preventing both the flow of medication from the catheter l4 and retrograde flow of blood into the catheter 14.
  • valves 24 will open, as best seen in FIGS. 4 and 5. Opening of valves 24 allows the medication of flow outwardly through each of the valves 24 and into the bloodstream of artery 12. Because there are a plurality of valves 24 provided around the entire circumference of the catheter 14 near its distal end 16, this allows the medication to be discharged uniformly and evenly thus providing greatly improved diffusion of the medication into the bloodstream and eliminating sporadic and unpredictable drug levels at the injection site.
  • the catheter I4 is left in place, and the positive pressure applied to infuse the medication is stopped after each injection and the valves 24 will close preventing the retrograde flow of blood into the catheter I4.
  • the blood in the artery I2 would tend to clot at the site of the lesion sometimes even during treatment, and would start to clot immediately after treatment was discontinued if the catheter was left in place.
  • the invention eliminates these problems by allowing the catheter I4 to be inserted and left in place during the entire time of the treatment without clogging even though the treatment may be quite prolonged.
  • the catheter 14a includes a cannula or tube 18a having a distal end 160.
  • a valve tip 30 which is formed of a material having a modulus of elasticity less than the material from which the tube 18a is formed.
  • the valve tip 30 is affixed to the distal end 160 in any suitable manner and completely encloses the otherwise open end of the tube 18a.
  • Formed around the periphery of the valve tip 30 are a plurality of slits or valves 240.
  • the slits or valves 240 are shown in a closed position which is their condition if the pressure inside of the catheter 14a is approximately that of the blood inside of the artery 12.
  • the valves 240 are shown in an open position which will occur if the pressure applied to the medication inside of the catheter 14a is greater than the blood pressure in the artery 12.
  • the second embodiment of FIGS. 6 and 7 has all of the advantages and features of the first embodiment, the only difference being that the catheter 14 of the first embodiment has a distal end 16 of a relatively hard material thus facilitating insertion.
  • the catheter 14a of the second embodi ment has a soft easily deformable valve tip 30. In either case, the insertion technique is the same with the catheter being inserted immediately after the artery wall is punctured with a suitable instrument.
  • a catheter employing the principles of the inveniton is of tremendous benefit in any procedure requiring the prolonged infusion of medication into the arterial tree either continuously or periodically over a prolonged time.
  • a properly designed catheter employing the principles of the invention may be used for intermittent intravenous administration of all types of medications including such techniques as the scalp-vein heparin lock technique. It will be obvious to those skilled in the art that a variety of techniques and treatments can be employed with a catheter made according to the principles of the invention.
  • catheters can be built according to the invention in various diameters with various specified rates of flow, the rate of flow being a function of the infusion pressure, the modulus of elasticity of the valve segment, the thickness of the valve segment, diameter of the catheter and number and size of the slits forming the valves.
  • a catheter for use in arterial infusion of fluids and the like comprising a cannula formed of a material sufficiently rigid to facilitate insertion thereof into an artery, said cannula having a distal end and a proximal end, a part of said cannula at the distal end having a plurality of cutout portions spaced around the circumference of said cannula and separating said distal end from the main body of the cannula, said cutout portions being separated by ribs extending longitudinally between the main body of said cannula and its distal end which ribs are formed integrally with said cannula, a flexible material extending completely over each of said cutout portions along the inside surface of said cannula and having a modulus of elasticity less than the modulus of elasticity for the material which forms said cannula, the flexible material covering each of said cutout portions having a plurality of slits therein to provide for discharge of fluid from inside of said cannula through said slits when

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A catheter for prolonged infusion of medication into an artery. The catheter has a unique tip design employing the flap valve principle to assure uniform and steady diffusion of the medication into the bloodstream and also to inhibit retrograde flow of blood into the catheter thereby minimizing clotting and the resulting blockage of the medication flow.

Description

United States Patent Spencer June 10, 1975 [54] ARTERIAL INFUSION CATHETER 3,565,079 2/1971 Jackson 128/351 [76] Inventor: David L. Spencer, 1243 N State St., OTHER PUBLICATIONS 60606 Reynolds et al. Surgery, Dec. 1965, Vol. 58, No. 6, [22] Filed: Nov. 2, 1973 pp. 938-940.
[211 Appl' No: 4l2'l99 Primary Examiner-Dalton L. Truluck Attorney, Agent. or Firm-James C. Nemmers; Haven [52] US. Cl 128/214 R; 128/274; 128/348; E. Simmons Int. 1 1 [58] Field of Search 128/214 R, 214.4, 240,
123/241 348 349 R 349 B, 349 Bv, 350 R, A catheter for prolonged mfuslon of medlcatlon into 350 v 35' 274 an artery. The catheter has a unique tip design employing the flap valve principle to assure uniform and [56] References Cited steady diffusion of the medication into the bloodstream and also to inhibit retrograde flow of blood UNITED STATES PATENTS into the catheter thereby minimizing clotting and the 28/348 X resulting blockage of the medication flow eyer t. 3.] 11.125 11/1963 Schulte .4 128/350 V 2 Claims, 7 Drawing Figures ARTERIAL INFUSION CATHETER BACKGROUND OF THE INVENTION In the care and treatment of hospitalized patients, catheters of various types are used to carry out the necessary treatments. Some catheters are used for drainage, some for infusion and some for both purposes. Also, depending upon the particular treatment, the catheters may be used for either short term or prolonged treatment. In the area of regional intra-arterial infusion, catheters are used to inject or infuse medication into the bloodstream. For example, in certain malignant tumors, arterial catheters are used for the regional infusion of chemotheraputic agents over prolonged periods. Thus, once the catheter has been inserted, it can be fixed in place and utilized for continuous infusion or for periodic infusion over prolonged periods. In this manner, the trauma of repeated punctures and re-insertions of the catheter can be kept to a mini mum. However, in using prolonged intra-arterial infusion several difficulties are encountered. Quite frequently, the blood will clot around the distal end of the catheter and cause premature cessation of the treatment. Also, with arterial catheters of presently known design, there is an inadequate mixing of the medication with the bloodstream which results in sporadic and unpredictable drug levels at the sight of the lesion. When clotting around the end of the catheter occurs resulting in blockage of the flow of medication, the catheter must be withdrawn, cleaned and reinserted. Since clotting is unpredictable, the infusion process must be closely watched so that cessation of the flow of medication can be quickly detected and corrective action taken. Thus, patients receiving medication through intra-arterial infusion must be closely watched and if problems result the patient quite often must suffer the trauma of withdrawal and re-insertion of the catheter a number of times during the course of the treatment. It is a principal object of my invention to overcome these disadvantages of prior art catheters so that more effective treatment can be accomplished with a minimum of trauma and pain to the patient.
SUMMARY OF THE INVENTION The invention provides a catheter design in which the distal end inserted into the artery is provided with a flexible portion containing one or more slits which serve as valves. When positive pressure is applied to start the infusion process, the slits will open and allow the medication to enter the arterial flow of blood. During the time that positive pressure is being applied, clotting cannot occur to block the flow, and if the positive pressure is withdrawn the slits will close to shut off the flow of medication and inhibit the retrograde flow of blood into the catheter thereby preventing blockage of the catheter. Also, with the multiple valve design of the catheter, and using positive pressure to inject the medication, greatly improved diffusion of the medication into the bloodstream is achieved.
BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a view of a portion of an artery, partly in section, and showing a catheter employing the principles of the invention in place in the artery;
FIG. 2 is a perspective view of the end of the catheter and showing the valves in a closed position;
FIG. 3 is a sectional view taken on line 33 of FIG.
FIG. 4 is a perspective view similar to FIG. 2 but showing the valves in an open position;
FIG. 5 is a sectional view taken on the line S5 of FIG. 4;
FIG. 6 is a perspective view showing the tip of a catheter employing the principles of the invention as disclosed in another embodiment thereof; and
FIG. 7 is a view similar to FIG. 6 but showing the valves of the catheter of the second embodiment in an open position.
DESCRIPTION OF THE PREFERRED EMBODIMENTS OF THE INVENTION In FIG. 1 there is shown in section the wall 10 of an artery 12 in which the flow of blood is in the direction indicated by the arrows. In employing the technique of intra-arterial infusion, the artery in punctured by a suitable instrument (not shown) and then the tip of a catheter 14 is inserted to the desired depth and with its distal end 16 pointing downstream. The catheter 14 consists of a cannula or hollow tube 18 the proximal end 19 of which is attached to a source of medication (not shown). By force of gravity or other means of applying a positive pressure, the medication flows through the tube 18 and is discharged through the distal end 16 into the bloodstream.
At or near the distal end I6 of the catheter 14 the tube 18 is provided with a plurality of cutout portions or windows 20 which are formed in between connecting ribs 22 that interconnect the tube I8 and the distal end 16 of the catheter I4. Each of the windows 20 is covered with a material having a modulus of elasticity less than the material from which the tube 18 is made. Formed in the material covering each of the windows 20 is a plurality of cuts or slits 24 which provide valves through which fluid introduced into the catheter I4 may be discharged. As best seen in FIGS. 2 and 3, when the pressure inside of the catheter 14 is approximately that of the blood in the artery 12, the valves 24 will be closed thus preventing both the flow of medication from the catheter l4 and retrograde flow of blood into the catheter 14. However, when the pressure applied to the medication in the catheter 14 is slightly greater than the blood pressure, the valves 24 will open, as best seen in FIGS. 4 and 5. Opening of valves 24 allows the medication of flow outwardly through each of the valves 24 and into the bloodstream of artery 12. Because there are a plurality of valves 24 provided around the entire circumference of the catheter 14 near its distal end 16, this allows the medication to be discharged uniformly and evenly thus providing greatly improved diffusion of the medication into the bloodstream and eliminating sporadic and unpredictable drug levels at the injection site. If the prolonged treatment requires repeated, regular injections of medication for limited periods of time, the catheter I4 is left in place, and the positive pressure applied to infuse the medication is stopped after each injection and the valves 24 will close preventing the retrograde flow of blood into the catheter I4. With prior art devices, the blood in the artery I2 would tend to clot at the site of the lesion sometimes even during treatment, and would start to clot immediately after treatment was discontinued if the catheter was left in place. The invention eliminates these problems by allowing the catheter I4 to be inserted and left in place during the entire time of the treatment without clogging even though the treatment may be quite prolonged.
In FIGS. 6 and 7 there is shown another embodiment of the invention, and parts corresponding to those of the first embodiment will be referred to by the same reference numeral followed by the latter a. Thus, in the second embodiment, the catheter 14a includes a cannula or tube 18a having a distal end 160. At the distal end 160 of tube 180 there is provided a valve tip 30 which is formed of a material having a modulus of elasticity less than the material from which the tube 18a is formed. The valve tip 30 is affixed to the distal end 160 in any suitable manner and completely encloses the otherwise open end of the tube 18a. Formed around the periphery of the valve tip 30 are a plurality of slits or valves 240. In FIG. 6, the slits or valves 240 are shown in a closed position which is their condition if the pressure inside of the catheter 14a is approximately that of the blood inside of the artery 12. In FIG. 7, the valves 240 are shown in an open position which will occur if the pressure applied to the medication inside of the catheter 14a is greater than the blood pressure in the artery 12. The second embodiment of FIGS. 6 and 7 has all of the advantages and features of the first embodiment, the only difference being that the catheter 14 of the first embodiment has a distal end 16 of a relatively hard material thus facilitating insertion. On the other hand, the catheter 14a of the second embodi ment has a soft easily deformable valve tip 30. In either case, the insertion technique is the same with the catheter being inserted immediately after the artery wall is punctured with a suitable instrument.
A catheter employing the principles of the inveniton is of tremendous benefit in any procedure requiring the prolonged infusion of medication into the arterial tree either continuously or periodically over a prolonged time. Also, a properly designed catheter employing the principles of the invention may be used for intermittent intravenous administration of all types of medications including such techniques as the scalp-vein heparin lock technique. It will be obvious to those skilled in the art that a variety of techniques and treatments can be employed with a catheter made according to the principles of the invention.
l have described my invention in connection with two preferred embodiments thereof. It will be obvious to those skilled in the art that the materials used in the catheter can be of any suitable material, it being important only that the valve portion have a modulus of elasticity less than the cannula. the number, size and actual placement of the slits which form the valves can be varied as will be obvious to those skilled in the art. Obviously, catheters can be built according to the invention in various diameters with various specified rates of flow, the rate of flow being a function of the infusion pressure, the modulus of elasticity of the valve segment, the thickness of the valve segment, diameter of the catheter and number and size of the slits forming the valves.
It will be further obvious that various revisions and modifications can be made in the specific preferred embodiments disclosed herein without departing from the spirit and scope of the invention. It is my intention, however, that all such revisions, modifications and uses will be included within the scope of the following claims.
I claim:
1. A catheter for use in arterial infusion of fluids and the like, said catheter comprising a cannula formed of a material sufficiently rigid to facilitate insertion thereof into an artery, said cannula having a distal end and a proximal end, a part of said cannula at the distal end having a plurality of cutout portions spaced around the circumference of said cannula and separating said distal end from the main body of the cannula, said cutout portions being separated by ribs extending longitudinally between the main body of said cannula and its distal end which ribs are formed integrally with said cannula, a flexible material extending completely over each of said cutout portions along the inside surface of said cannula and having a modulus of elasticity less than the modulus of elasticity for the material which forms said cannula, the flexible material covering each of said cutout portions having a plurality of slits therein to provide for discharge of fluid from inside of said cannula through said slits when the fluid pressure in said cannula exceeds the pressure on the outside of said cannula which preventing the retrograde flow of fluid into said cannula regardless of the pressure difference between the inside and outside of said cannula.
2. The catheter of claim 1 in which there is at least one row of slits in the flexible material covering each of said cutout portions, the said row extending longitudinally along the cutout portion, and said cutout portions extend around the entire circumference of said cannula between said ribs.

Claims (2)

1. A catheter for use in arterial infusion of fluids and the like, said catheter comprising a cannula formed of a material sufficiently rigid to facilitate insertion thereof into an artery, said cannula having a distal end and a proximal end, a part of said cannula at the distal end having a plurality of cutout portions spaced around the circumference of said cannula and separating said distal end from the main body of the cannula, said cutout portions being separated by ribs extending longitudinally between the main body of said cannula and its distal end which ribs are formed integrally with said cannula, a flexible material extending completely over each of said cutout portions along the inside surface of said cannula and having A modulus of elasticity less than the modulus of elasticity for the material which forms said cannula, the flexible material covering each of said cutout portions having a plurality of slits therein to provide for discharge of fluid from inside of said cannula through said slits when the fluid pressure in said cannula exceeds the pressure on the outside of said cannula which preventing the retrograde flow of fluid into said cannula regardless of the pressure difference between the inside and outside of said cannula.
2. The catheter of claim 1 in which there is at least one row of slits in the flexible material covering each of said cutout portions, the said row extending longitudinally along the cutout portion, and said cutout portions extend around the entire circumference of said cannula between said ribs.
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Cited By (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029104A (en) * 1976-03-08 1977-06-14 Kerber Charles W Calibrated leak balloon micro-catheter
US4182342A (en) * 1978-04-28 1980-01-08 Med-Pro, Ltd. Naso-gastric feeding device and method of inserting same
WO1980002230A1 (en) * 1979-04-13 1980-10-30 Univ Minnesota Check valve catheter
FR2460678A1 (en) * 1979-07-12 1981-01-30 Critikon Inc CATHETER ASSEMBLY FOR LIQUID INFUSIONS
US4327722A (en) * 1979-08-20 1982-05-04 Groshong Leroy E Methods and apparatus for intravenous therapy and hyperalimentation
EP0064284A2 (en) * 1981-05-02 1982-11-10 Reiner Dr. Nessler Intravenous catheter
EP0125844A2 (en) * 1983-05-03 1984-11-21 Catheter Technology Corporation Valved two-way catheter
US4657536A (en) * 1979-04-13 1987-04-14 Regents Of The University Of Minnesota Check valve catheter
US4681564A (en) * 1985-10-21 1987-07-21 Landreneau Michael D Catheter assembly having balloon extended flow path
US4701166A (en) * 1983-05-03 1987-10-20 Catheter Technology Corp. Valved two-way catheter
US4704111A (en) * 1983-04-22 1987-11-03 Moss James P Nasogastric feeding tube
US4714461A (en) * 1985-11-07 1987-12-22 Becton, Dickinson And Company Catheter assembly with air purging feature
US4722725A (en) * 1983-04-12 1988-02-02 Interface Biomedical Laboratories, Inc. Methods for preventing the introduction of air or fluid into the body of a patient
EP0263645A2 (en) * 1986-10-06 1988-04-13 Catheter Technology Corporation Catheter
US4759751A (en) * 1985-11-07 1988-07-26 Becton, Dickinson And Company Catheter assembly with air purging feature
US4801297A (en) * 1984-06-01 1989-01-31 Edward Weck Incorporated Catheter having slit tip
US4883461A (en) * 1987-05-15 1989-11-28 Interface Biomedical Laboratories Corp. Safety needle sheath in anti-reflux catheter having novel valve means
US4946448A (en) * 1989-10-23 1990-08-07 Kendall Mcgaw Laboratories, Inc. Check valve for use with intravenous pump
US5021044A (en) * 1989-01-30 1991-06-04 Advanced Cardiovascular Systems, Inc. Catheter for even distribution of therapeutic fluids
US5049132A (en) * 1990-01-08 1991-09-17 Cordis Corporation Balloon catheter for delivering therapeutic agents
US5100385A (en) * 1989-01-27 1992-03-31 C. R. Bard, Inc. Fast purge balloon dilatation catheter
US5147318A (en) * 1991-03-04 1992-09-15 Board Of Regents, The University Of Texas System Valved arterial catheter
US5160325A (en) * 1986-10-06 1992-11-03 C. R. Bard, Inc. Catheter with novel lumens shapes
US5163921A (en) * 1990-10-04 1992-11-17 Feiring Andrew J Valved perfusion cardiovascular catheters
US5169393A (en) * 1990-09-04 1992-12-08 Robert Moorehead Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5201722A (en) * 1990-09-04 1993-04-13 Moorehead Robert H Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5205834A (en) * 1990-09-04 1993-04-27 Moorehead H Robert Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5215527A (en) * 1991-12-12 1993-06-01 Becton, Dickinson And Company Catheter introducer assembly
US5224933A (en) * 1992-03-23 1993-07-06 C. R. Bard, Inc. Catheter purge device
US5250034A (en) * 1990-09-17 1993-10-05 E-Z-Em, Inc. Pressure responsive valve catheter
US5261885A (en) * 1992-07-14 1993-11-16 Cook Pacemaker Corporation Valved catheter
US5267979A (en) * 1990-09-17 1993-12-07 E-Z-Em, Inc. Pressure responsive valve catheter
US5304155A (en) * 1992-07-14 1994-04-19 Cook Pacemaker Corporation Valved catheter
US5337730A (en) * 1992-06-18 1994-08-16 The United States Of America As Represented By The Secretary Of The Air Force Endoscope cleansing catheter and method of use
US5458570A (en) * 1991-01-22 1995-10-17 May, Jr.; James W. Absorbable catheter and method of using the same
US5472418A (en) * 1994-07-28 1995-12-05 Palestrant; Aubrey M. Flattened collapsible vascular catheter
US5554119A (en) * 1991-08-02 1996-09-10 Scimed Drug delivery catheter with manifold
US5562617A (en) * 1994-01-18 1996-10-08 Finch, Jr.; Charles D. Implantable vascular device
EP0693300A3 (en) * 1994-06-20 1997-03-26 Minimed Inc Side slit catheter
US5797869A (en) * 1987-12-22 1998-08-25 Vas-Cath Incorporated Multiple lumen catheter
US5807356A (en) * 1994-01-18 1998-09-15 Vasca, Inc. Catheter with valve
US5807349A (en) * 1997-03-10 1998-09-15 United States Surgical Corporation Catheter having valve mechanism
US5908413A (en) * 1997-10-03 1999-06-01 Scimed Life Systems, Inc. Radiopaque catheter and method of manufacture thereof
US5928203A (en) * 1997-10-01 1999-07-27 Boston Scientific Corporation Medical fluid infusion and aspiration
US5989206A (en) * 1997-10-31 1999-11-23 Biolink Corporation Apparatus and method for the dialysis of blood
US6036682A (en) * 1997-12-02 2000-03-14 Scimed Life Systems, Inc. Catheter having a plurality of integral radiopaque bands
US6042569A (en) * 1994-01-18 2000-03-28 Vasca, Inc. Subcutaneously implanted cannula and methods for vascular access
US6053901A (en) * 1994-01-18 2000-04-25 Vasca, Inc. Subcutaneously implanted cannula and method for arterial access
US6077258A (en) * 1997-10-03 2000-06-20 Scimed Life Systems, Inc. Braided angiography catheter having full length radiopacity and controlled flexibility
US6117125A (en) * 1996-05-02 2000-09-12 Cook Incorporated Method for predetermining uniform flow rate of a fluid from a tubular body and device therefrom
US6395208B1 (en) 1999-01-25 2002-05-28 Atrium Medical Corporation Method of making an expandable fluoropolymer device
US6436071B1 (en) 1999-06-08 2002-08-20 The Trustees Of Columbia University In The City Of New York Intravascular systems for corporeal cooling
US6464662B1 (en) * 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US20020183716A1 (en) * 1999-01-25 2002-12-05 Atrium Medical Corporation Expandable fluoropolymer device and method of making
US6524300B2 (en) 2000-01-03 2003-02-25 Angiodynamics, Inc. Infusion catheter with non-uniform drug delivery density
US6572579B1 (en) 2000-09-13 2003-06-03 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US20040097880A1 (en) * 2002-11-19 2004-05-20 Angiodynamics, Inc. Combination thrombolytic infusion catheter and dilator system
US20040243106A1 (en) * 1997-12-29 2004-12-02 Rupal Ayer Osmotic delivery device with membrane plug retention mechanism
US20050043703A1 (en) * 2003-08-21 2005-02-24 Greg Nordgren Slit valves for catheter tips and methods
US20050107738A1 (en) * 2000-07-21 2005-05-19 Slater Charles R. Occludable intravascular catheter for drug delivery and method of using the same
US20050113798A1 (en) * 2000-07-21 2005-05-26 Slater Charles R. Methods and apparatus for treating the interior of a blood vessel
US6955661B1 (en) 1999-01-25 2005-10-18 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
WO2006023203A1 (en) * 2004-08-19 2006-03-02 Vein Rx, Inc. An occludable intravascular catheter for drug delivery and method of using the same
US20060116635A1 (en) * 2004-11-29 2006-06-01 Med Enclosure L.L.C. Arterial closure device
US20060137345A1 (en) * 2004-12-23 2006-06-29 Doosan Infracore Co., Ltd. Compressed air supplying apparatus for use in heavy construction equipments
US20060149218A1 (en) * 2003-02-05 2006-07-06 Slater Charles R Methods and apparatus for treating the interior of a blood vessel
EP1682199A2 (en) * 2003-11-15 2006-07-26 Medrad, Inc. Catheter for diagnostic imaging and therapeutic procedures
US20060167399A1 (en) * 2005-01-25 2006-07-27 Solar Ronald J Systems and methods for selective thermal treatment
US20070106303A1 (en) * 2005-07-07 2007-05-10 Dodick Jack M Surgical instrument
US20080086109A1 (en) * 2004-11-29 2008-04-10 Paul Shabty Arterial closure device
US20080097339A1 (en) * 2006-08-31 2008-04-24 Medrad, Inc. Catheter with filtering and sensing elements
US20080200873A1 (en) * 2007-02-16 2008-08-21 Alejandro Espinosa Methods and Apparatus for Infusing the Interior of a Blood Vessel
US20090209907A1 (en) * 2008-02-15 2009-08-20 Paul John Grata Single-Use Indicator For A Surgical Instrument And A Surgical Instrument Incorporating Same
US20100198186A1 (en) * 2009-02-03 2010-08-05 Ackermann Simon Dual-lumen catheter for medical device delivery systems
US20110313399A1 (en) * 2009-02-09 2011-12-22 Vein Flow Inc. Intravenous cannula
WO2013016598A2 (en) * 2011-07-27 2013-01-31 Sangart, Inc. Methods for reducing reperfusion injury using a hemoglobin-based carbon monoxide carrier
US20140012209A1 (en) * 2012-07-05 2014-01-09 Tyco Healthcare Group Lp Valved Tip Catheters
WO2014042708A1 (en) * 2012-09-17 2014-03-20 Abbott Vascular Multi-lumen catheter
US8876792B2 (en) 2008-04-08 2014-11-04 Karolinska Institutet Innovations Ab Endoluminal medical access device
US20150165161A1 (en) * 2006-04-21 2015-06-18 Bayer Medical Care Inc. Catheters And Related Equipment
US9314584B1 (en) * 2011-06-27 2016-04-19 Bayer Healthcare Llc Method and apparatus for fractional flow reserve measurements
US9352117B2 (en) 2010-10-05 2016-05-31 Cook Medical Technologies Llc Infusion catheter and methods
US9447892B2 (en) 2008-05-21 2016-09-20 Angiodynamics, Inc. Pressure activated valve for high flow rate and pressure venous access applications
US9642962B2 (en) 2008-09-26 2017-05-09 Covidien Lp Valved hemodialysis catheter
US20180028340A1 (en) * 2012-11-29 2018-02-01 Boehringer Technologies, Lp Systems and methods for performing bariatric surgery
WO2019023259A3 (en) * 2017-07-25 2019-04-25 Affera, Inc. Ablation catheters and related systems and methods
CN110201289A (en) * 2019-05-15 2019-09-06 武汉福脉医疗科技有限公司 A kind of medicament elution sacculus and preparation method thereof
AU2020223708B2 (en) * 2019-09-18 2022-02-24 Heraeus Medical Gmbh Device for temporarily, locally applying fluids
AU2020217324B2 (en) * 2019-09-18 2022-03-24 Heraeus Medical Gmbh Device for temporary, local administration of fluids
US11344314B2 (en) * 2015-03-02 2022-05-31 Accurate Medical Therapeutics Ltd. Catheters with side openings for modifying and delivering suspensions to a subject
US11612734B2 (en) 2009-07-13 2023-03-28 Angiodynamics, Inc. Method to secure an elastic component in a valve
US11628243B2 (en) 2003-06-27 2023-04-18 Angiodynamics, Inc. Pressure actuated valve with improved biasing member
US11653929B2 (en) 2017-11-02 2023-05-23 Accurate Medical Therapeutics Ltd. Embolization catheter with integral filter

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2470665A (en) * 1947-07-08 1949-05-17 Stiehl Charles William Suction apparatus
US3020913A (en) * 1958-07-15 1962-02-13 William T Heyer Surgical drain
US3111125A (en) * 1961-11-06 1963-11-19 Rudolf R Schulte Drainage device
US3565079A (en) * 1968-04-09 1971-02-23 Richard Robert Jackson Self-inflating endotracheal tube

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2470665A (en) * 1947-07-08 1949-05-17 Stiehl Charles William Suction apparatus
US3020913A (en) * 1958-07-15 1962-02-13 William T Heyer Surgical drain
US3111125A (en) * 1961-11-06 1963-11-19 Rudolf R Schulte Drainage device
US3565079A (en) * 1968-04-09 1971-02-23 Richard Robert Jackson Self-inflating endotracheal tube

Cited By (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029104A (en) * 1976-03-08 1977-06-14 Kerber Charles W Calibrated leak balloon micro-catheter
US4182342A (en) * 1978-04-28 1980-01-08 Med-Pro, Ltd. Naso-gastric feeding device and method of inserting same
US4657536A (en) * 1979-04-13 1987-04-14 Regents Of The University Of Minnesota Check valve catheter
WO1980002230A1 (en) * 1979-04-13 1980-10-30 Univ Minnesota Check valve catheter
FR2460678A1 (en) * 1979-07-12 1981-01-30 Critikon Inc CATHETER ASSEMBLY FOR LIQUID INFUSIONS
US4327722A (en) * 1979-08-20 1982-05-04 Groshong Leroy E Methods and apparatus for intravenous therapy and hyperalimentation
EP0064284A2 (en) * 1981-05-02 1982-11-10 Reiner Dr. Nessler Intravenous catheter
EP0064284A3 (en) * 1981-05-02 1983-11-09 Reiner Dr. Nessler Intravenous catheter
US4722725A (en) * 1983-04-12 1988-02-02 Interface Biomedical Laboratories, Inc. Methods for preventing the introduction of air or fluid into the body of a patient
US4704111A (en) * 1983-04-22 1987-11-03 Moss James P Nasogastric feeding tube
US4701166A (en) * 1983-05-03 1987-10-20 Catheter Technology Corp. Valved two-way catheter
EP0125844A2 (en) * 1983-05-03 1984-11-21 Catheter Technology Corporation Valved two-way catheter
EP0125844A3 (en) * 1983-05-03 1985-10-30 Catheter Technology Corporation Valved two-way catheter
US4801297A (en) * 1984-06-01 1989-01-31 Edward Weck Incorporated Catheter having slit tip
US4681564A (en) * 1985-10-21 1987-07-21 Landreneau Michael D Catheter assembly having balloon extended flow path
US4714461A (en) * 1985-11-07 1987-12-22 Becton, Dickinson And Company Catheter assembly with air purging feature
US4759751A (en) * 1985-11-07 1988-07-26 Becton, Dickinson And Company Catheter assembly with air purging feature
EP0263645A3 (en) * 1986-10-06 1989-08-16 Catheter Technology Corporation Catheters and methods of using such catheters
EP0263645A2 (en) * 1986-10-06 1988-04-13 Catheter Technology Corporation Catheter
US5160325A (en) * 1986-10-06 1992-11-03 C. R. Bard, Inc. Catheter with novel lumens shapes
US4883461A (en) * 1987-05-15 1989-11-28 Interface Biomedical Laboratories Corp. Safety needle sheath in anti-reflux catheter having novel valve means
US5797869A (en) * 1987-12-22 1998-08-25 Vas-Cath Incorporated Multiple lumen catheter
US6206849B1 (en) 1987-12-22 2001-03-27 Vas-Cath Incorporated Multiple lumen catheter
US7229429B2 (en) 1987-12-22 2007-06-12 Vas-Cath Inc. Multiple lumen catheter
US5100385A (en) * 1989-01-27 1992-03-31 C. R. Bard, Inc. Fast purge balloon dilatation catheter
US5021044A (en) * 1989-01-30 1991-06-04 Advanced Cardiovascular Systems, Inc. Catheter for even distribution of therapeutic fluids
US4946448A (en) * 1989-10-23 1990-08-07 Kendall Mcgaw Laboratories, Inc. Check valve for use with intravenous pump
US5049132A (en) * 1990-01-08 1991-09-17 Cordis Corporation Balloon catheter for delivering therapeutic agents
US5169393A (en) * 1990-09-04 1992-12-08 Robert Moorehead Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5201722A (en) * 1990-09-04 1993-04-13 Moorehead Robert H Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5205834A (en) * 1990-09-04 1993-04-27 Moorehead H Robert Two-way outdwelling slit valving of medical liquid flow through a cannula and methods
US5267979A (en) * 1990-09-17 1993-12-07 E-Z-Em, Inc. Pressure responsive valve catheter
US5250034A (en) * 1990-09-17 1993-10-05 E-Z-Em, Inc. Pressure responsive valve catheter
US5163921A (en) * 1990-10-04 1992-11-17 Feiring Andrew J Valved perfusion cardiovascular catheters
US5458570A (en) * 1991-01-22 1995-10-17 May, Jr.; James W. Absorbable catheter and method of using the same
US5147318A (en) * 1991-03-04 1992-09-15 Board Of Regents, The University Of Texas System Valved arterial catheter
US5716340A (en) * 1991-08-02 1998-02-10 Scimed Life Systems, Inc. Blood perfusion catheter
US5554119A (en) * 1991-08-02 1996-09-10 Scimed Drug delivery catheter with manifold
US5558642A (en) * 1991-08-02 1996-09-24 Scimed Life Systems, Inc. Drug delivery catheter
US5215527A (en) * 1991-12-12 1993-06-01 Becton, Dickinson And Company Catheter introducer assembly
US5224933A (en) * 1992-03-23 1993-07-06 C. R. Bard, Inc. Catheter purge device
US5337730A (en) * 1992-06-18 1994-08-16 The United States Of America As Represented By The Secretary Of The Air Force Endoscope cleansing catheter and method of use
US5261885A (en) * 1992-07-14 1993-11-16 Cook Pacemaker Corporation Valved catheter
US5304155A (en) * 1992-07-14 1994-04-19 Cook Pacemaker Corporation Valved catheter
US6042569A (en) * 1994-01-18 2000-03-28 Vasca, Inc. Subcutaneously implanted cannula and methods for vascular access
US6056717A (en) * 1994-01-18 2000-05-02 Vasca, Inc. Implantable vascular device
US5755780A (en) * 1994-01-18 1998-05-26 Vasca, Inc. Implantable vascular device
US5807356A (en) * 1994-01-18 1998-09-15 Vasca, Inc. Catheter with valve
US5562617A (en) * 1994-01-18 1996-10-08 Finch, Jr.; Charles D. Implantable vascular device
US5713859A (en) * 1994-01-18 1998-02-03 Vasca, Inc. Implantable vascular device
US6398764B1 (en) 1994-01-18 2002-06-04 Vasca. Inc. Subcutaneously implanted cannula and method for arterial access
US6053901A (en) * 1994-01-18 2000-04-25 Vasca, Inc. Subcutaneously implanted cannula and method for arterial access
EP0693300A3 (en) * 1994-06-20 1997-03-26 Minimed Inc Side slit catheter
US5472418A (en) * 1994-07-28 1995-12-05 Palestrant; Aubrey M. Flattened collapsible vascular catheter
US5618267A (en) * 1994-07-28 1997-04-08 Palestrant; Aubrey M. Method for establishing collapsible infusion conduit
US6117125A (en) * 1996-05-02 2000-09-12 Cook Incorporated Method for predetermining uniform flow rate of a fluid from a tubular body and device therefrom
US5807349A (en) * 1997-03-10 1998-09-15 United States Surgical Corporation Catheter having valve mechanism
US6723075B2 (en) 1997-10-01 2004-04-20 Christopher T. Davey Medical fluid infusion and aspiration
US5928203A (en) * 1997-10-01 1999-07-27 Boston Scientific Corporation Medical fluid infusion and aspiration
US6120483A (en) * 1997-10-01 2000-09-19 Boston Scientific Corporation Medical fluid infusion and aspiration
US6436077B1 (en) 1997-10-01 2002-08-20 Boston Scientific Corporation Medical fluid infusion and aspiration
US5908413A (en) * 1997-10-03 1999-06-01 Scimed Life Systems, Inc. Radiopaque catheter and method of manufacture thereof
US6077258A (en) * 1997-10-03 2000-06-20 Scimed Life Systems, Inc. Braided angiography catheter having full length radiopacity and controlled flexibility
US5989206A (en) * 1997-10-31 1999-11-23 Biolink Corporation Apparatus and method for the dialysis of blood
US6620118B1 (en) 1997-10-31 2003-09-16 Biolink Corporation Apparatus and method for the dialysis of blood
US6036682A (en) * 1997-12-02 2000-03-14 Scimed Life Systems, Inc. Catheter having a plurality of integral radiopaque bands
US20040243106A1 (en) * 1997-12-29 2004-12-02 Rupal Ayer Osmotic delivery device with membrane plug retention mechanism
US9050442B2 (en) 1999-01-25 2015-06-09 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
US7637886B2 (en) 1999-01-25 2009-12-29 Atrium Medical Corporation Expandable fluoropolymer device and method of making
US20020183716A1 (en) * 1999-01-25 2002-12-05 Atrium Medical Corporation Expandable fluoropolymer device and method of making
US6395208B1 (en) 1999-01-25 2002-05-28 Atrium Medical Corporation Method of making an expandable fluoropolymer device
US6955661B1 (en) 1999-01-25 2005-10-18 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
US6605106B2 (en) 1999-06-08 2003-08-12 The Trustees Of Columbia University In The City Of New York Intravascular systems for corporeal cooling
US6436071B1 (en) 1999-06-08 2002-08-20 The Trustees Of Columbia University In The City Of New York Intravascular systems for corporeal cooling
US20060036303A1 (en) * 1999-06-08 2006-02-16 Schwartz Arthur E Intravascular systems for corporeal cooling
US6524300B2 (en) 2000-01-03 2003-02-25 Angiodynamics, Inc. Infusion catheter with non-uniform drug delivery density
US20050113798A1 (en) * 2000-07-21 2005-05-26 Slater Charles R. Methods and apparatus for treating the interior of a blood vessel
US20050107738A1 (en) * 2000-07-21 2005-05-19 Slater Charles R. Occludable intravascular catheter for drug delivery and method of using the same
US6464662B1 (en) * 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US6572579B1 (en) 2000-09-13 2003-06-03 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
US7641645B2 (en) 2002-11-19 2010-01-05 Angio Dynamics, Inc. Combination thrombolytic infusion catheter and dilator system
US20050113800A1 (en) * 2002-11-19 2005-05-26 Israel Schur Combination thrombolytic infusion catheter and dilator system
US20040097880A1 (en) * 2002-11-19 2004-05-20 Angiodynamics, Inc. Combination thrombolytic infusion catheter and dilator system
US20060149218A1 (en) * 2003-02-05 2006-07-06 Slater Charles R Methods and apparatus for treating the interior of a blood vessel
US11628243B2 (en) 2003-06-27 2023-04-18 Angiodynamics, Inc. Pressure actuated valve with improved biasing member
US20050043703A1 (en) * 2003-08-21 2005-02-24 Greg Nordgren Slit valves for catheter tips and methods
EP1682199A4 (en) * 2003-11-15 2008-03-12 Medrad Inc Catheter for diagnostic imaging and therapeutic procedures
EP1682199A2 (en) * 2003-11-15 2006-07-26 Medrad, Inc. Catheter for diagnostic imaging and therapeutic procedures
US20070073271A1 (en) * 2003-11-15 2007-03-29 Brucker Gregory G Catheter for diagnostic imaging and therapeutic procedures
US20070135791A1 (en) * 2004-08-19 2007-06-14 Slater Charles R Method for Infusing the Interior of a Blood Vessel
EP1781354A1 (en) * 2004-08-19 2007-05-09 Vein RX Inc. An occludable intravascular catheter for drug delivery and method of using the same
EP1781354A4 (en) * 2004-08-19 2008-04-09 Vein Rx Inc An occludable intravascular catheter for drug delivery and method of using the same
WO2006023203A1 (en) * 2004-08-19 2006-03-02 Vein Rx, Inc. An occludable intravascular catheter for drug delivery and method of using the same
US20060116635A1 (en) * 2004-11-29 2006-06-01 Med Enclosure L.L.C. Arterial closure device
US20080086109A1 (en) * 2004-11-29 2008-04-10 Paul Shabty Arterial closure device
US20060137345A1 (en) * 2004-12-23 2006-06-29 Doosan Infracore Co., Ltd. Compressed air supplying apparatus for use in heavy construction equipments
US20060167399A1 (en) * 2005-01-25 2006-07-27 Solar Ronald J Systems and methods for selective thermal treatment
US7704220B2 (en) 2005-01-25 2010-04-27 Thermopeutix, Inc. Systems and methods for selective thermal treatment
US20060167398A1 (en) * 2005-01-25 2006-07-27 Thermopeutix Inc. System and methods for selective thermal treatment
US7789846B2 (en) 2005-01-25 2010-09-07 Thermopeutix, Inc. System and methods for selective thermal treatment
US20070106303A1 (en) * 2005-07-07 2007-05-10 Dodick Jack M Surgical instrument
US7736329B2 (en) * 2005-07-07 2010-06-15 Dodick Jack M Surgical instrument with a sleeve for use during eye surgery
US20150165161A1 (en) * 2006-04-21 2015-06-18 Bayer Medical Care Inc. Catheters And Related Equipment
US10850066B2 (en) * 2006-04-21 2020-12-01 Bayer Healthcare Llc Catheters and related equipment
US8876754B2 (en) 2006-08-31 2014-11-04 Bayer Medical Care Inc. Catheter with filtering and sensing elements
US20080097339A1 (en) * 2006-08-31 2008-04-24 Medrad, Inc. Catheter with filtering and sensing elements
US20080200873A1 (en) * 2007-02-16 2008-08-21 Alejandro Espinosa Methods and Apparatus for Infusing the Interior of a Blood Vessel
US20090209907A1 (en) * 2008-02-15 2009-08-20 Paul John Grata Single-Use Indicator For A Surgical Instrument And A Surgical Instrument Incorporating Same
US8157747B2 (en) 2008-02-15 2012-04-17 Lary Research & Development, Llc Single-use indicator for a surgical instrument and a surgical instrument incorporating same
US8876792B2 (en) 2008-04-08 2014-11-04 Karolinska Institutet Innovations Ab Endoluminal medical access device
US9447892B2 (en) 2008-05-21 2016-09-20 Angiodynamics, Inc. Pressure activated valve for high flow rate and pressure venous access applications
US11679248B2 (en) 2008-05-21 2023-06-20 Angiodynamics, Inc. Pressure activated valve for high flow rate and pressure venous access applications
US9642962B2 (en) 2008-09-26 2017-05-09 Covidien Lp Valved hemodialysis catheter
WO2010090953A3 (en) * 2009-02-03 2010-10-21 Abbott Cardiovascular Systems Inc. Dual-lumen catheter for medical device delivery systems
US20100198186A1 (en) * 2009-02-03 2010-08-05 Ackermann Simon Dual-lumen catheter for medical device delivery systems
US20110313399A1 (en) * 2009-02-09 2011-12-22 Vein Flow Inc. Intravenous cannula
US11612734B2 (en) 2009-07-13 2023-03-28 Angiodynamics, Inc. Method to secure an elastic component in a valve
US9352117B2 (en) 2010-10-05 2016-05-31 Cook Medical Technologies Llc Infusion catheter and methods
US9615755B2 (en) 2011-06-27 2017-04-11 Bayer Healthcare Llc Method and apparatus for fractional flow reserve measurements
US9314584B1 (en) * 2011-06-27 2016-04-19 Bayer Healthcare Llc Method and apparatus for fractional flow reserve measurements
WO2013016598A2 (en) * 2011-07-27 2013-01-31 Sangart, Inc. Methods for reducing reperfusion injury using a hemoglobin-based carbon monoxide carrier
WO2013016598A3 (en) * 2011-07-27 2013-03-21 Sangart, Inc. Methods for reducing reperfusion injury using a hemoglobin-based carbon monoxide carrier
US10143822B2 (en) * 2012-07-05 2018-12-04 Covidien Lp Valved tip catheters
US20140012209A1 (en) * 2012-07-05 2014-01-09 Tyco Healthcare Group Lp Valved Tip Catheters
US9259552B2 (en) 2012-09-17 2016-02-16 Abbott Cardiovascular Systems Inc. Multi-lumen catheter
WO2014042708A1 (en) * 2012-09-17 2014-03-20 Abbott Vascular Multi-lumen catheter
US20180028340A1 (en) * 2012-11-29 2018-02-01 Boehringer Technologies, Lp Systems and methods for performing bariatric surgery
US10888446B2 (en) * 2012-11-29 2021-01-12 Boehringer Technologies, Lp Systems and methods for performing bariatric surgery
US11344314B2 (en) * 2015-03-02 2022-05-31 Accurate Medical Therapeutics Ltd. Catheters with side openings for modifying and delivering suspensions to a subject
WO2019023259A3 (en) * 2017-07-25 2019-04-25 Affera, Inc. Ablation catheters and related systems and methods
US11751937B2 (en) 2017-07-25 2023-09-12 Affera, Inc. Ablation catheters and related systems and methods
US11653929B2 (en) 2017-11-02 2023-05-23 Accurate Medical Therapeutics Ltd. Embolization catheter with integral filter
CN110201289B (en) * 2019-05-15 2021-09-03 武汉福脉医疗科技有限公司 Drug eluting balloon and preparation method thereof
CN110201289A (en) * 2019-05-15 2019-09-06 武汉福脉医疗科技有限公司 A kind of medicament elution sacculus and preparation method thereof
AU2020223708B2 (en) * 2019-09-18 2022-02-24 Heraeus Medical Gmbh Device for temporarily, locally applying fluids
AU2020217324B2 (en) * 2019-09-18 2022-03-24 Heraeus Medical Gmbh Device for temporary, local administration of fluids

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