|
| US4145408 | 31 Oct 1977 | 20 Mar 1979 | The Procter & Gamble Company | Controlled release article |
| US4156604 | 15 Sep 1978 | 29 May 1979 | Minnesota Mining and Manufacturing Company | Controlled delivery of corrosion inhibitors for silver recovery cartridges |
| US4177256 | 29 Nov 1977 | 4 Dic 1979 | ALZA Corporation | Osmotic bursting drug delivery device |
| US4190642 | 11 May 1979 | 26 Feb 1980 | Alza Corporation | Ocular therapeutic system for dispensing a medication formulation |
| US4267138 | 19 Sep 1977 | 12 May 1981 | Richter Gedeon Vegyeszeti Gyar Rt. | Coating ensuring a controlled release of active ingredients of biologically active compositions, particularly pharmaceutical compositions and a process for preparation of biologically active compositions ensuring controlled release of active ingredients |
| US4304765 | 14 Oct 1980 | 8 Dic 1981 | Alza Corporation | Ocular insert housing steroid in two different therapeutic forms |
| US4333850 | 15 Jun 1979 | 8 Jun 1982 | Borg-Warner Corporation | Filled polymer composition for automatic addition of a corrosion inhibitor to a coolant system |
| US4432964 | 27 Dic 1982 | 21 Feb 1984 | ALZA Corporation | Topical composition containing steroid in two forms released independently from polymeric carrier |
| US4478818 | 5 Ene 1984 | 23 Oct 1984 | Alza Corporation | Ocular preparation housing steroid in two different therapeutic forms |
| US4557925 | 5 Sep 1984 | 10 Dic 1985 | AB Ferrosan | Membrane-coated sustained-release tablets and method |
| US4564364 | 26 May 1983 | 14 Ene 1986 | ALZA Corporation | Active agent dispenser |
| US4629619 | 19 Sep 1985 | 16 Dic 1986 | AB Ferrosan | Membrane-coated sustained-release tablets and method |
| US4629620 | 19 Sep 1985 | 16 Dic 1986 | AB Ferrosan | Membrane-coated sustained-release tablets and method |
| US4704282 | 29 Jun 1984 | 3 Nov 1987 | Alza Corporation | Transdermal therapeutic system having improved delivery characteristics |
| US4725439 | 13 Ene 1986 | 16 Feb 1988 | ALZA Corporation | Transdermal drug delivery device |
| US4761289 | 10 Oct 1986 | 2 Ago 1988 | International Minerals & Chemical Corp. | Sustained release implant and method for preparing same |
| US4781924 | 9 Nov 1987 | 1 Nov 1988 | ALZA Corporation | Transdermal drug delivery device |
| US4837027 | 9 Ago 1988 | 6 Jun 1989 | ALZA Corporation | Transdermal drug delivery device |
| US4874366 | 19 Dic 1988 | 17 Oct 1989 | Baxter Internatiional Inc. | Housing enabling passive mixing of a beneficial agent with a diluent |
| US4898733 | 4 Nov 1985 | 6 Feb 1990 | International Minerals & Chemical Corp. | Layered, compression molded device for the sustained release of a beneficial agent |
| US4908027 | 12 Sep 1986 | 13 Mar 1990 | ALZA Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
| US4917895 | 14 Jul 1988 | 17 Abr 1990 | ALZA Corporation | Transdermal drug delivery device |
| US4923607 | 30 Nov 1987 | 8 May 1990 | Nitto Denko Corporation | Membrane containing a liquid active substance and process for the production of same |
| US4978537 | 19 Abr 1989 | 18 Dic 1990 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
| US5024657 | 4 May 1990 | 18 Jun 1991 | Baxter International Inc. | Drug delivery apparatus and method preventing local and systemic toxicity |
| US5071656 | 14 Nov 1988 | 10 Dic 1991 | ALZA Corporation | Delayed onset transdermal delivery device |
| US5091186 | 15 Ago 1989 | 25 Feb 1992 | Cygnus Therapeutic Systems | Biphasic transdermal drug delivery device |
| US5108762 | 30 Oct 1990 | 28 Abr 1992 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
| US5124157 | 18 Ago 1989 | 23 Jun 1992 | Cygnus Therapeutic Systems Farmos Group Ltd. | Method and device for administering dexmedetomidine transdermally |
| US5128155 | 20 Dic 1990 | 7 Jul 1992 | Wm. Wrigley Jr. Company | Flavor releasing structures for chewing gum |
| US5141750 | 14 Nov 1988 | 25 Ago 1992 | Alza Corporation | Delayed onset transdermal delivery device |
| US5154939 | 8 Nov 1991 | 13 Oct 1992 | Wm. Wrigley Jr. Company | Use of salt to improve extrusion encapsulation of chewing gum ingredients |
| US5165944 | 18 Oct 1991 | 24 Nov 1992 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
| US5198251 | 16 Dic 1991 | 30 Mar 1993 | Wm. Wrigley Jr. Company | Gradual release structures for chewing gum |
| US5229148 | 20 Feb 1992 | 20 Jul 1993 | Wm. Wrigley Jr. Company | Method of combining active ingredients with polyvinyl acetates |
| US5284660 | 21 Ago 1992 | 8 Feb 1994 | Alza Corporation | Delayed onset transdermal delivery device |
| US5342623 | 18 Jun 1993 | 30 Ago 1994 | Alza Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
| US5364627 | 21 Jul 1992 | 15 Nov 1994 | Wm. Wrigley Jr. Company | Gradual release structures made from fiber spinning techniques |
| US5508038 | 16 Abr 1990 | 16 Abr 1996 | Alza Corporation | Polyisobutylene adhesives for transdermal devices |
| US5564439 | 27 Dic 1994 | 15 Oct 1996 | George J. Picha | Infusion device for soft tissue |
| US5706807 | 11 Oct 1996 | 13 Ene 1998 | Applied Medical Research | Sensor device covered with foam membrane |
| US5798065 | 2 Oct 1997 | 25 Ago 1998 | George J. Picha | Collagen disruptive surface morphology for implants |
| US5819742 | 30 Oct 1997 | 13 Oct 1998 | Family Health International | Vaginal device for preventing conception or the transmission of sexually transmitted diseases, or both |
| US5853758 | 10 Jul 1996 | 29 Dic 1998 | Pfizer Inc. | Preparation of tablets of increased strength |
| US5962011 | 24 Jun 1997 | 5 Oct 1999 | Schering-Plough Healthcare Products, Inc. | Device for delivery of dermatological ingredients |
| US6110500 | 25 Mar 1998 | 29 Ago 2000 | Temple University | Coated tablet with long term parabolic and zero-order release kinetics |
| US6126956 | 22 Dic 1998 | 3 Oct 2000 | Axxia Technologies | Subcutaneous implant |
| US6130200 | 18 Dic 1997 | 10 Oct 2000 | Alza Corporation | Gel composition and methods |
| US6331311 | 18 Dic 1997 | 18 Dic 2001 | ALZA Corporation | Injectable depot gel composition and method of preparing the composition |
| US6468961 | 13 Jul 2000 | 22 Oct 2002 | Alza Corporation | Gel composition and methods |
| US6673767 | 21 Mar 2000 | 6 Ene 2004 | Alza Corporation | Gel composition and methods |
| US7118376 | 14 Mar 2001 | 10 Oct 2006 | Coll Partners Ltd. | System for the controlled delivery of an active material to a dental site |
| US7829109 | 14 Nov 2002 | 9 Nov 2010 | Durect Corporation | Catheter injectable depot compositions and uses thereof |
| USRE39588 | 31 Oct 1990 | 24 Abr 2007 | Alza Corporation | Transdermal drug delivery device |