US4456007A - Inhaler - Google Patents

Inhaler Download PDF

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Publication number
US4456007A
US4456007A US06/329,108 US32910881A US4456007A US 4456007 A US4456007 A US 4456007A US 32910881 A US32910881 A US 32910881A US 4456007 A US4456007 A US 4456007A
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US
United States
Prior art keywords
vapor
inhaler
chemical
cover
sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
US06/329,108
Inventor
Shinroku Nakao
Yoshiyasu Ishii
Kazuo Nagata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Combi Corp
Original Assignee
Combi Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP17821380U external-priority patent/JPS635728Y2/ja
Priority claimed from JP17821480U external-priority patent/JPS5757707Y2/ja
Priority claimed from JP1133581U external-priority patent/JPS57126252U/ja
Application filed by Combi Corp filed Critical Combi Corp
Assigned to COMBI CO., LTD., reassignment COMBI CO., LTD., ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: ISHII, YOSHIYASU, NAGATA, KAZUO, NAKAO, SHINROKU
Application granted granted Critical
Publication of US4456007A publication Critical patent/US4456007A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A61M11/065—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type using steam as driving gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0023—Mouthpieces therefor retractable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/08—Supports for equipment

Definitions

  • This invention relates to an inhaler having a novel construction.
  • inhalers which are so designed that chemical vapors together with steam are jetted to maintain one's health or to cure the throat are known in the art.
  • these conventional inhalers are disadvantageous in the following point. Since the vapor feeding sleeve for guiding a stream of mixed chemical vapors is set at a fixed angle, the user must set himself so as to be in agreement with the angle of the vapor feeding sleeve thereby to introduce the stream of vapors to his throat. Thus, his posture is not natural in using the inhaler.
  • a chemical is sucked into a stream of steam jetted by a vapor producing unit.
  • the inhaler has a chemical container and a condensed water container in addition to the vapor producing unit.
  • the conventional inhaler suffers from the following difficulty: Since no protective means is provided for the chemical container or a chemical sucking nozzle inserted into the chemical container, steam deposited on the chemical sucking nozzle flows down into the chemical container, to dilute the chemical in the chemical container.
  • the present invention is intended to overcome the above-described drawbacks accompanying a conventional inhaler, by providing an inhaler as described below.
  • An object of the invention is to provide an inhaler which is so designed that its vapor feeding sleeve is set out of the cover only when the inhaler is used, and it is set in the cover when it is not in use.
  • Another object of the invention is to provide an inhaler which is so designed that the vapor feeding sleeve can be tilted at a desired angle in using the inhaler.
  • Still another object of the invention is to provide a nozzle mechanism for an inhaler which is so designed as to protect a chemical from being diluted by water condensed from jetted steam.
  • FIG. 1 is a perspective view of an inhaler according to the present invention
  • FIG. 2 is an exploded view of an inhaler body and its cover, with a part of the cover sectioned;
  • FIG. 3 is a vertical sectional view of the inhaler shown in FIG. 1;
  • FIG. 4 is a perspective view of the inhaler from which the cover has been removed.
  • FIG. 5 is a side view of the essential components of the inhaler shown in FIG. 4.
  • An inhaler comprises: a vapor producing unit body 1 an inner construction of which will be described in detail later; and a cover 3 having a rotatable vapor feeding sleeve 2 adapted to feed a mixed chemical vapor, in combination. It is preferable that the cover 3 be made of plastic.
  • the vapor producing unit body 1 has a housing 11 on which a vapor producing unit 12 and a chemical container 56 are provided.
  • the vapor producing unit 12 an inner mechanism of which is well known in the art is provided with a vapor jetting nozzle 14 and a chemical sucking nozzle 15.
  • the cover 3 is detachably fitted in the upper opening of the vapor producing unit body 1.
  • a nozzle path opening 31 is formed in the front portion of the cover 3.
  • the mixed chemical vapor feeding sleeve 2 is pivotably mounted in the opening 31 in such a manner that it can be tilted at a desired angle.
  • the sleeve 2 is substantially in the form of a tapered cylinder the diameter of which is gradually reduced towards the outer end.
  • Locking grooves 21 and a locking groove 22 which is used when the nozzle is turned in an opposite direction are formed radially in each side wall of the sleeve 2 is near the sleeve base, in such a manner that a selected one of the grooves is engaged with a locking strip 32 which is protruded from each side inner wall of the cover 3.
  • each locking strip 32 is formed on a wall extending downwardly from the inner side wall of the cover 3 made of synthetic resin, the locking strip 32 is firmly engaged with the selected groove 21 or 22 formed in the side wall of the sleeve 2.
  • the angle of inclination of the vapor feeding sleeve 2 can be changed. Therefore, the user can set the vapor feeding sleeve at a suitable angle so that the vapor is naturally applied to the throat of the user who sits on the chair, in advance. Accordingly, even if he uses the inhaler for a long time, he will never become fatigued because his posture is natural in using the inhaler.
  • the sleeve 2 is turned in the direction of the arrow a in FIG. 1 until the locking groove 22 is engaged with locking strip 32, so that the sleeve 2 is stably held in the cover 3. Therefore, the vapor feeding sleeve 2 for applying the mixing chemical vapor to the throat can be held sanitarily.
  • FIGS. 4 and 5 A preferred construction of an inner mechanism of the vapor producing unit body 1 will now be described in detail with reference to FIGS. 4 and 5.
  • the vapor jetting nozzle 14 communicates through its base with a vapor producing unit 12 and the top end of the chemical sucking nozzle 15 is confronted with the top end of the vapor jetting nozzle 14 by means of an arm plate 44.
  • a water bypassing flange 45 is secured to the base of the chemical sucking nozzle 15.
  • the flange 45 extends radially from the base of the nozzle 15 to a suitable dimension.
  • reference numeral 55 designates a tube of rubber or the like one end of which is coupled to the lower end portion of the chemical sucking nozzle 15, with the other end inserted into a chemical container 56; and 57, a container into which condensed water drops.
  • the water bypassing flange 45 is provided integral with the base of the chemical sucking nozzle 15 according to the invention. Therefore, as shown in FIG. 5, water reduced from the steam in the inhaler, which otherwise would flow down the sucking nozzle 15 into the chemical container 56, is directed towards the reduced water receiving container 57 by the water bypassing flange 45 in association with a deflector 49. Thus, the chemical in the chemical container 56 will never be diluted by the condensed water.

Abstract

An inhaler comprises a vapor producing unit, and a cover incorporating a vapor feeding nozzle. The vapor feeding nozzle is pivotally mounted on the cover in such a manner that the vapor feeding nozzle can be tilted at a desired angle. Also, a novel construction of an inner mechanism for the inhaler is disclosed.

Description

BACKGROUND OF THE INVENTION
This invention relates to an inhaler having a novel construction.
A variety of inhalers which are so designed that chemical vapors together with steam are jetted to maintain one's health or to cure the throat are known in the art. However, these conventional inhalers are disadvantageous in the following point. Since the vapor feeding sleeve for guiding a stream of mixed chemical vapors is set at a fixed angle, the user must set himself so as to be in agreement with the angle of the vapor feeding sleeve thereby to introduce the stream of vapors to his throat. Thus, his posture is not natural in using the inhaler.
On the other hand, in producing a chemical vapor with an ordinary inhaler, a chemical is sucked into a stream of steam jetted by a vapor producing unit. The inhaler has a chemical container and a condensed water container in addition to the vapor producing unit.
However, the conventional inhaler suffers from the following difficulty: Since no protective means is provided for the chemical container or a chemical sucking nozzle inserted into the chemical container, steam deposited on the chemical sucking nozzle flows down into the chemical container, to dilute the chemical in the chemical container.
SUMMARY OF THE INVENTION
The present invention is intended to overcome the above-described drawbacks accompanying a conventional inhaler, by providing an inhaler as described below.
An object of the invention is to provide an inhaler which is so designed that its vapor feeding sleeve is set out of the cover only when the inhaler is used, and it is set in the cover when it is not in use.
Another object of the invention is to provide an inhaler which is so designed that the vapor feeding sleeve can be tilted at a desired angle in using the inhaler.
Still another object of the invention is to provide a nozzle mechanism for an inhaler which is so designed as to protect a chemical from being diluted by water condensed from jetted steam.
BRIEF DESCRIPTION OF THE DRAWINGS
In the accompanying drawings:
FIG. 1 is a perspective view of an inhaler according to the present invention;
FIG. 2 is an exploded view of an inhaler body and its cover, with a part of the cover sectioned;
FIG. 3 is a vertical sectional view of the inhaler shown in FIG. 1;
FIG. 4 is a perspective view of the inhaler from which the cover has been removed; and
FIG. 5 is a side view of the essential components of the inhaler shown in FIG. 4.
PREFERRED EMBODIMENTS OF THE INVENTION
One embodiment of this invention will be described with reference to the accompanying drawings. An inhaler according to the invention comprises: a vapor producing unit body 1 an inner construction of which will be described in detail later; and a cover 3 having a rotatable vapor feeding sleeve 2 adapted to feed a mixed chemical vapor, in combination. It is preferable that the cover 3 be made of plastic. The vapor producing unit body 1 has a housing 11 on which a vapor producing unit 12 and a chemical container 56 are provided. The vapor producing unit 12 an inner mechanism of which is well known in the art is provided with a vapor jetting nozzle 14 and a chemical sucking nozzle 15. The cover 3 is detachably fitted in the upper opening of the vapor producing unit body 1. A nozzle path opening 31 is formed in the front portion of the cover 3. The mixed chemical vapor feeding sleeve 2 is pivotably mounted in the opening 31 in such a manner that it can be tilted at a desired angle. The sleeve 2 is substantially in the form of a tapered cylinder the diameter of which is gradually reduced towards the outer end. Locking grooves 21 and a locking groove 22 which is used when the nozzle is turned in an opposite direction are formed radially in each side wall of the sleeve 2 is near the sleeve base, in such a manner that a selected one of the grooves is engaged with a locking strip 32 which is protruded from each side inner wall of the cover 3. It is desirable that the locking strip 32 be protruded from the inner wall of the cover 3 to the extent that the height of protrusion of the locking strip 32 will not obstruct the rotation of the vapor feeding sleeve 2, for instance to 0.5 to 1 mm. Since each locking strip 32 is formed on a wall extending downwardly from the inner side wall of the cover 3 made of synthetic resin, the locking strip 32 is firmly engaged with the selected groove 21 or 22 formed in the side wall of the sleeve 2.
As is apparent from the above description, according to the present invention, the angle of inclination of the vapor feeding sleeve 2 can be changed. Therefore, the user can set the vapor feeding sleeve at a suitable angle so that the vapor is naturally applied to the throat of the user who sits on the chair, in advance. Accordingly, even if he uses the inhaler for a long time, he will never become fatigued because his posture is natural in using the inhaler. After the inhaler has been used, the sleeve 2 is turned in the direction of the arrow a in FIG. 1 until the locking groove 22 is engaged with locking strip 32, so that the sleeve 2 is stably held in the cover 3. Therefore, the vapor feeding sleeve 2 for applying the mixing chemical vapor to the throat can be held sanitarily.
A preferred construction of an inner mechanism of the vapor producing unit body 1 will now be described in detail with reference to FIGS. 4 and 5. In FIGS. 4 and 5, the vapor jetting nozzle 14 communicates through its base with a vapor producing unit 12 and the top end of the chemical sucking nozzle 15 is confronted with the top end of the vapor jetting nozzle 14 by means of an arm plate 44. A water bypassing flange 45 is secured to the base of the chemical sucking nozzle 15. The flange 45 extends radially from the base of the nozzle 15 to a suitable dimension. Further, in FIG. 5, reference numeral 55 designates a tube of rubber or the like one end of which is coupled to the lower end portion of the chemical sucking nozzle 15, with the other end inserted into a chemical container 56; and 57, a container into which condensed water drops.
As described above, the water bypassing flange 45 is provided integral with the base of the chemical sucking nozzle 15 according to the invention. Therefore, as shown in FIG. 5, water reduced from the steam in the inhaler, which otherwise would flow down the sucking nozzle 15 into the chemical container 56, is directed towards the reduced water receiving container 57 by the water bypassing flange 45 in association with a deflector 49. Thus, the chemical in the chemical container 56 will never be diluted by the condensed water.
Only one preferred embodiment of the invention has been described. It is apparent that various modifications are possible within the scope of the accompanying claims.

Claims (6)

What is claimed is:
1. An inhaler comprising a body having a vapor producing unit therein, cover means detachably fitting on said body and having aperture means therein, a vapor feeding sleeve for directing a vapor into a user's mouth, and pivot means for pivotally mounting said vapor feeding sleeve on said cover means for movement between a first plurality of positions wherein said sleeve extends outwardly through said aperture means at a desired angle and a second position wherein said sleeve is disposed completely within said cover, said aperture means permitting pivotal movement of said sleeve between said first and second positions only when said cover means is removed from said body.
2. An inhaler as claimed in claim 1 wherein said vapor producing unit includes a vapor jetting nozzle and a chemical jetting nozzle, said vapor jetting nozzle and said chemical jetting nozzle are coupled to each other by a connecting arm member so that said vapor jetting nozzle and said chemical jetting nozzle confront each other to define a predetermined angle.
3. An inhaler as claimed in claim 2, wherein said chemical nozzle has a water bypass flange, said vapor producing body further including a chemical container and a condensed water receiving container, said water bypass flange being so positioned that condensed water may be collected into said condensed water receiving container.
4. An inhaler as claimed in claim 1, wherein said pivot means for mounting includes a plurality of locking grooves and a locking strip engageable with selected one of said locking grooves.
5. An inhaler as claimed in claim 4, wherein said locking grooves are formed in said vapor feeding sleeve and said locking strip is formed on said cover.
6. An inhaler as claimed in claim 5, wherein said locking grooves include a single locking groove engaged with said locking strip when the vapor feeding sleeve is rotated inwardly and received in said cover.
US06/329,108 1980-12-12 1981-12-09 Inhaler Expired - Fee Related US4456007A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP55-178213[U] 1980-12-12
JP17821380U JPS635728Y2 (en) 1980-12-12 1980-12-12
JP17821480U JPS5757707Y2 (en) 1980-12-12 1980-12-12
JP55-178214[U]JPX 1980-12-12
JP1133581U JPS57126252U (en) 1981-01-29 1981-01-29

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US4456007A true US4456007A (en) 1984-06-26

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US06/329,108 Expired - Fee Related US4456007A (en) 1980-12-12 1981-12-09 Inhaler

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US (1) US4456007A (en)
EP (1) EP0055537B1 (en)
CA (1) CA1170939A (en)
DE (1) DE3167658D1 (en)

Cited By (43)

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Publication number Priority date Publication date Assignee Title
US4890340A (en) * 1988-09-26 1990-01-02 Lovitt Harold B Self-contained hand-held bidet
WO1991007940A1 (en) * 1989-12-01 1991-06-13 Lovitt Harold B Self-contained hand-held bidet
US5277343A (en) * 1991-08-22 1994-01-11 Parsonage Harvey J Container with pouring spout
US6158431A (en) * 1998-02-13 2000-12-12 Tsi Incorporated Portable systems and methods for delivery of therapeutic material to the pulmonary system
US20030180351A1 (en) * 1998-11-06 2003-09-25 Reinhard Gluck Pharmaceutically active composition and dispensing device
US6698421B2 (en) * 1999-12-03 2004-03-02 Medel S.P.A. Apparatus for nebulizing a liquid, in particular for medical use
US20050150491A1 (en) * 2004-01-13 2005-07-14 Yu-Yu Chen Steam inhaler
US20080099013A1 (en) * 2005-01-06 2008-05-01 Mark Andrew Graham Gas-Treatment Devices
US20080127970A1 (en) * 1999-07-23 2008-06-05 Mannkind Corporation Unit Dose Capsules and Dry Powder Inhaler
US20080173300A1 (en) * 2007-01-24 2008-07-24 Michael Justman Portable vaporized substance delivery system
US20080295753A1 (en) * 2005-10-19 2008-12-04 Nancy Sue Hardwig Fabric having a removable guide
US20090241949A1 (en) * 2008-03-27 2009-10-01 Smutney Chad C Dry powder inhalation system
US20100163020A1 (en) * 2008-12-30 2010-07-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for administering an inhalable compound
US20110226715A1 (en) * 2009-06-02 2011-09-22 Knape & Vogt Manufacturing Company Storage Systems And Methods Of Use Of The Same
US20120234874A1 (en) * 2011-03-18 2012-09-20 Gojo Industries, Inc. Wall-mounted and countertop-mounted dispenser
US8950397B2 (en) 1999-07-23 2015-02-10 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US9192675B2 (en) 2008-06-13 2015-11-24 Mankind Corporation Dry powder inhaler and system for drug delivery
US9220687B2 (en) 2008-12-29 2015-12-29 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9233159B2 (en) 2011-10-24 2016-01-12 Mannkind Corporation Methods and compositions for treating pain
US9241903B2 (en) 2006-02-22 2016-01-26 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
USD748242S1 (en) * 2014-07-11 2016-01-26 H. Stuart Campbell Inhaler mouthpiece
US9283193B2 (en) 2005-09-14 2016-03-15 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US9346766B2 (en) 2004-08-20 2016-05-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
US9364436B2 (en) 2011-06-17 2016-06-14 Mannkind Corporation High capacity diketopiperazine microparticles and methods
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
US9630930B2 (en) 2009-06-12 2017-04-25 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US9662461B2 (en) 2008-06-13 2017-05-30 Mannkind Corporation Dry powder drug delivery system and methods
US9675674B2 (en) 2004-08-23 2017-06-13 Mannkind Corporation Diketopiperazine salts for drug delivery and related methods
US9700690B2 (en) 2002-03-20 2017-07-11 Mannkind Corporation Inhalation apparatus
US9706944B2 (en) 2009-11-03 2017-07-18 Mannkind Corporation Apparatus and method for simulating inhalation efforts
US9802012B2 (en) 2012-07-12 2017-10-31 Mannkind Corporation Dry powder drug delivery system and methods
US9801925B2 (en) 1999-06-29 2017-10-31 Mannkind Corporation Potentiation of glucose elimination
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US9943571B2 (en) 2008-08-11 2018-04-17 Mannkind Corporation Use of ultrarapid acting insulin
US9983108B2 (en) 2009-03-11 2018-05-29 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10207065B2 (en) 2013-07-12 2019-02-19 John H. Silva Mouthpiece for inhalers
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10342938B2 (en) 2008-06-13 2019-07-09 Mannkind Corporation Dry powder drug delivery system
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10625034B2 (en) 2011-04-01 2020-04-21 Mannkind Corporation Blister package for pharmaceutical cartridges
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Publication number Priority date Publication date Assignee Title
US4890340A (en) * 1988-09-26 1990-01-02 Lovitt Harold B Self-contained hand-held bidet
US5097540A (en) * 1988-09-26 1992-03-24 Lovitt Harold B Self-contained hand-held bidet
WO1991007940A1 (en) * 1989-12-01 1991-06-13 Lovitt Harold B Self-contained hand-held bidet
US5277343A (en) * 1991-08-22 1994-01-11 Parsonage Harvey J Container with pouring spout
US6158431A (en) * 1998-02-13 2000-12-12 Tsi Incorporated Portable systems and methods for delivery of therapeutic material to the pulmonary system
US20030180351A1 (en) * 1998-11-06 2003-09-25 Reinhard Gluck Pharmaceutically active composition and dispensing device
US9801925B2 (en) 1999-06-29 2017-10-31 Mannkind Corporation Potentiation of glucose elimination
US8950397B2 (en) 1999-07-23 2015-02-10 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US20080127970A1 (en) * 1999-07-23 2008-06-05 Mannkind Corporation Unit Dose Capsules and Dry Powder Inhaler
US8671937B2 (en) 1999-07-23 2014-03-18 Mannkind Corporation Unit dose capsules and dry powder inhaler
US9061111B2 (en) 1999-07-23 2015-06-23 Mannkind Corporation Unit dose capsules and dry powder inhaler
US8146588B2 (en) * 1999-07-23 2012-04-03 Mannkind Corporation Unit dose capsules and dry powder inhaler
US6698421B2 (en) * 1999-12-03 2004-03-02 Medel S.P.A. Apparatus for nebulizing a liquid, in particular for medical use
US9700690B2 (en) 2002-03-20 2017-07-11 Mannkind Corporation Inhalation apparatus
US20050150491A1 (en) * 2004-01-13 2005-07-14 Yu-Yu Chen Steam inhaler
US9346766B2 (en) 2004-08-20 2016-05-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
US9796688B2 (en) 2004-08-20 2017-10-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
US10130685B2 (en) 2004-08-23 2018-11-20 Mannkind Corporation Diketopiperazine salts for drug delivery and related methods
US9675674B2 (en) 2004-08-23 2017-06-13 Mannkind Corporation Diketopiperazine salts for drug delivery and related methods
US20080099013A1 (en) * 2005-01-06 2008-05-01 Mark Andrew Graham Gas-Treatment Devices
US9604027B2 (en) 2005-01-06 2017-03-28 Smiths Group Plc Gas-treatment devices
US9446001B2 (en) 2005-09-14 2016-09-20 Mannkind Corporation Increasing drug affinity for crystalline microparticle surfaces
US10143655B2 (en) 2005-09-14 2018-12-04 Mannkind Corporation Method of drug formulation
US9283193B2 (en) 2005-09-14 2016-03-15 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US9717689B2 (en) 2005-09-14 2017-08-01 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
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CA1170939A (en) 1984-07-17
EP0055537B1 (en) 1984-12-05
EP0055537A1 (en) 1982-07-07
DE3167658D1 (en) 1985-01-17

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