US5964095A - Method and apparatus for cryogenic storage of thermolabile products - Google Patents
Method and apparatus for cryogenic storage of thermolabile products Download PDFInfo
- Publication number
- US5964095A US5964095A US08/877,763 US87776397A US5964095A US 5964095 A US5964095 A US 5964095A US 87776397 A US87776397 A US 87776397A US 5964095 A US5964095 A US 5964095A
- Authority
- US
- United States
- Prior art keywords
- product
- thermolabile
- robotic arm
- container
- storing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D25/00—Charging, supporting, and discharging the articles to be cooled
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
- F25D3/105—Movable containers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
Abstract
Description
______________________________________ PATENT NO. ISSUE DATE INVENTOR ______________________________________ U.S. PATENT DOCUMENTS 5,125,240 June 30, 1992 Knippscheer, et al. 5,233,844 August 10, 1993 Richard FOREIGN PATENT DOCUMENTS EP0 411 224 A2 February 2, 1991 Knippscheer, et al. WO91/02202 February 21, 1991 Richard WO91/02203 February 21, 1991 Knippscheer, et al. WO91/09521 July 11, 1991 Richard WO92/16800 October 1, 1992 Knippscheer, et al. WO93/03891 March 4, 1993 Knippscheer, et al. JP4-507,283 December 17, 1992 Knippscheer, et al. JP6-509,782 November 2, 1994 Knippscheer, et al. ______________________________________
Claims (15)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/877,763 US5964095A (en) | 1995-02-23 | 1997-06-16 | Method and apparatus for cryogenic storage of thermolabile products |
PCT/US1998/011408 WO1998058216A1 (en) | 1997-06-16 | 1998-06-15 | Method for cryogenic storage of thermolabile materials |
AU82531/98A AU8253198A (en) | 1997-06-16 | 1998-06-15 | Method for cryogenic storage of thermolabile materials |
JP50448399A JP2002511827A (en) | 1997-06-16 | 1998-06-15 | Low temperature storage method for heat resistant materials |
EP98932713A EP1012510A1 (en) | 1997-06-16 | 1998-06-15 | Method for cryogenic storage of thermolabile materials |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/393,558 US5638686A (en) | 1995-02-23 | 1995-02-23 | Method and apparatus for cryogenic storage of thermolabile products |
US08/877,763 US5964095A (en) | 1995-02-23 | 1997-06-16 | Method and apparatus for cryogenic storage of thermolabile products |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/393,558 Division US5638686A (en) | 1995-02-23 | 1995-02-23 | Method and apparatus for cryogenic storage of thermolabile products |
Publications (1)
Publication Number | Publication Date |
---|---|
US5964095A true US5964095A (en) | 1999-10-12 |
Family
ID=25370664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/877,763 Expired - Lifetime US5964095A (en) | 1995-02-23 | 1997-06-16 | Method and apparatus for cryogenic storage of thermolabile products |
Country Status (5)
Country | Link |
---|---|
US (1) | US5964095A (en) |
EP (1) | EP1012510A1 (en) |
JP (1) | JP2002511827A (en) |
AU (1) | AU8253198A (en) |
WO (1) | WO1998058216A1 (en) |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6302327B1 (en) * | 1997-06-16 | 2001-10-16 | Thermogenesis, Corp. | Method and apparatus for cryogenic storage of thermolabile products |
EP1223393A2 (en) * | 2001-01-12 | 2002-07-17 | Chart, Inc. | Liquid cryogen storage container |
WO2002077614A2 (en) * | 2001-03-23 | 2002-10-03 | Ortho-Mcneil Pharmaceutical, Inc. | Apparatus for the automation of chemical reaction kinetics studies |
US6608883B2 (en) * | 1999-08-11 | 2003-08-19 | Abbott Laboratories | Automated sample handling for X-ray crystallography |
US20040006999A1 (en) * | 2001-11-01 | 2004-01-15 | Integrated Biosystems, Inc. | Systems and methods for freezing, mixing and thawing biopharmacuetical material |
US6684646B2 (en) | 2001-05-22 | 2004-02-03 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical material |
US20040129003A1 (en) * | 2001-05-22 | 2004-07-08 | Integrated Biosystems, Inc. | Systems and methods for freezing and storing biopharmaceutical material |
US20050011202A1 (en) * | 2001-11-01 | 2005-01-20 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing, transporting and thawing biopharmacuetical material |
US20080050278A1 (en) * | 2006-08-25 | 2008-02-28 | Edward Francis Farina | System for automatically storing and reprocessing patient sample's in an automatic clinical analyzer |
US20080092581A1 (en) * | 2006-10-20 | 2008-04-24 | Cass Schumann | Cryogenic storage container system |
US8028532B2 (en) | 2006-03-06 | 2011-10-04 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
CN102495563A (en) * | 2011-12-31 | 2012-06-13 | 北京市红十字血液中心 | Blood intelligent control storage system and method thereof |
EP2664881A1 (en) | 2012-05-16 | 2013-11-20 | M & R Automation GmbH | Cryogenic storage system for thermolabile specimens |
CN104417908A (en) * | 2013-08-22 | 2015-03-18 | 国玺干细胞应用技术股份有限公司 | Biological product storage device with observation window |
US10661988B2 (en) | 2014-10-31 | 2020-05-26 | Tsubakimoto Chain Co. | Low temperature storage system, transport mechanism, and low temperature storage vessel |
WO2021236463A1 (en) * | 2020-05-18 | 2021-11-25 | TMRW Life Sciences, Inc. | Handling and tracking of biological specimens for cryogenic storage |
US11607691B2 (en) | 2019-10-29 | 2023-03-21 | TMRW Life Sciences, Inc. | Apparatus to facilitate transfer of biological specimens stored at cryogenic conditions |
US11632949B2 (en) | 2020-09-24 | 2023-04-25 | TMRW Life Sciences, Inc. | Cryogenic storage system with sensors to measure one or more parameters therewithin |
US11788783B2 (en) | 2017-11-07 | 2023-10-17 | MVE Biological Solutions US, LLC | Cryogenic freezer |
USD1002868S1 (en) | 2020-12-09 | 2023-10-24 | TMRW Life Sciences, Inc. | Cryogenic vial carrier |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITBO20020607A1 (en) | 2002-09-26 | 2004-03-27 | Cryorobotics | AUTOMATIC TEMPERATURE STORAGE SYSTEM |
TWI363032B (en) * | 2009-04-02 | 2012-05-01 | Healthbanks Biotech Co Ltd | Storage apparatus for storing products |
WO2015085287A1 (en) | 2013-12-07 | 2015-06-11 | Trumed Systems, Inc. | Automated smart storage of temperature sensitive products |
CN110589332B (en) * | 2019-10-08 | 2020-11-06 | 苏州贝康医疗器械有限公司 | Automated biological sample library |
EP4301137A1 (en) * | 2021-03-02 | 2024-01-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Storage system for cryo-em/ et samples |
Citations (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3662565A (en) * | 1969-02-27 | 1972-05-16 | Gram Brdr As | Freezing apparatus having a rotatable horizontal freezing structure |
US4090374A (en) * | 1975-05-23 | 1978-05-23 | Union Carbide Corporation | Apparatus for cryogenic freezing of fluid filled pouches |
US4245483A (en) * | 1979-05-14 | 1981-01-20 | Kabushiki Kaisha Toyo Seisakusho | System for purifying contaminated refrigerant and reproducing the same for use with freezing liquid spray refrigerator |
US4432214A (en) * | 1979-07-23 | 1984-02-21 | Samifi Babcock Samifi Internationale S.A. | Device for insertion and feed of products on the plates in a horizontal plate freezer |
US4551992A (en) * | 1983-09-09 | 1985-11-12 | C. Reichert Optische Werke, Ag. | Apparatus for cooling a biological or medical specimen |
US4757692A (en) * | 1987-12-14 | 1988-07-19 | Mcdonald Gordon K | Embryo freezer |
US4768356A (en) * | 1986-07-11 | 1988-09-06 | Messer. Griesheim Gmbh | Arrangement for the transport of a cryogenic refrigerant to the work area of a robot |
US4920763A (en) * | 1986-10-23 | 1990-05-01 | Phillip B. Provest | Chilling apparatus |
EP0411224A2 (en) * | 1989-08-04 | 1991-02-06 | CRYO-CELL INTERNATIONAL INC. (a Delaware corporation) | Cryogenic storage apparatus |
WO1991002202A1 (en) * | 1989-08-04 | 1991-02-21 | Cryo-Cell International, Inc. | Multichamber storage apparatus and related method |
WO1991002203A1 (en) * | 1989-08-04 | 1991-02-21 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
WO1991009521A1 (en) * | 1989-12-22 | 1991-07-11 | Cryo-Cell International, Inc. | Identification process and related method for use in preparing a biological sample |
US5125240A (en) * | 1989-08-04 | 1992-06-30 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
WO1992016800A1 (en) * | 1991-03-18 | 1992-10-01 | Cryo-Cell International, Inc. | Method and apparatus for use in low-temperature storage |
WO1993003891A1 (en) * | 1991-08-15 | 1993-03-04 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE62578T1 (en) * | 1984-11-09 | 1991-05-15 | Cryologic Pty Ltd | CRYOGENIC SYSTEM FOR BIOLOGICAL MATERIAL. |
US5638686A (en) * | 1995-02-23 | 1997-06-17 | Thermogenesis Corporation | Method and apparatus for cryogenic storage of thermolabile products |
-
1997
- 1997-06-16 US US08/877,763 patent/US5964095A/en not_active Expired - Lifetime
-
1998
- 1998-06-15 WO PCT/US1998/011408 patent/WO1998058216A1/en not_active Application Discontinuation
- 1998-06-15 AU AU82531/98A patent/AU8253198A/en not_active Abandoned
- 1998-06-15 JP JP50448399A patent/JP2002511827A/en not_active Ceased
- 1998-06-15 EP EP98932713A patent/EP1012510A1/en not_active Withdrawn
Patent Citations (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3662565A (en) * | 1969-02-27 | 1972-05-16 | Gram Brdr As | Freezing apparatus having a rotatable horizontal freezing structure |
US4090374A (en) * | 1975-05-23 | 1978-05-23 | Union Carbide Corporation | Apparatus for cryogenic freezing of fluid filled pouches |
US4245483A (en) * | 1979-05-14 | 1981-01-20 | Kabushiki Kaisha Toyo Seisakusho | System for purifying contaminated refrigerant and reproducing the same for use with freezing liquid spray refrigerator |
US4432214A (en) * | 1979-07-23 | 1984-02-21 | Samifi Babcock Samifi Internationale S.A. | Device for insertion and feed of products on the plates in a horizontal plate freezer |
US4551992A (en) * | 1983-09-09 | 1985-11-12 | C. Reichert Optische Werke, Ag. | Apparatus for cooling a biological or medical specimen |
US4768356A (en) * | 1986-07-11 | 1988-09-06 | Messer. Griesheim Gmbh | Arrangement for the transport of a cryogenic refrigerant to the work area of a robot |
US4920763A (en) * | 1986-10-23 | 1990-05-01 | Phillip B. Provest | Chilling apparatus |
US4757692A (en) * | 1987-12-14 | 1988-07-19 | Mcdonald Gordon K | Embryo freezer |
EP0411224A2 (en) * | 1989-08-04 | 1991-02-06 | CRYO-CELL INTERNATIONAL INC. (a Delaware corporation) | Cryogenic storage apparatus |
WO1991002202A1 (en) * | 1989-08-04 | 1991-02-21 | Cryo-Cell International, Inc. | Multichamber storage apparatus and related method |
WO1991002203A1 (en) * | 1989-08-04 | 1991-02-21 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
US5125240A (en) * | 1989-08-04 | 1992-06-30 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
JPH04507283A (en) * | 1989-08-04 | 1992-12-17 | クライオ―セル・インターナショナル・インク | Multi-chamber containment device and related methods |
WO1991009521A1 (en) * | 1989-12-22 | 1991-07-11 | Cryo-Cell International, Inc. | Identification process and related method for use in preparing a biological sample |
WO1992016800A1 (en) * | 1991-03-18 | 1992-10-01 | Cryo-Cell International, Inc. | Method and apparatus for use in low-temperature storage |
US5176202A (en) * | 1991-03-18 | 1993-01-05 | Cryo-Cell International, Inc. | Method and apparatus for use in low-temperature storage |
WO1993003891A1 (en) * | 1991-08-15 | 1993-03-04 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
US5233844A (en) * | 1991-08-15 | 1993-08-10 | Cryo-Cell International, Inc. | Storage apparatus, particularly with automatic insertion and retrieval |
JPH06509782A (en) * | 1991-08-15 | 1994-11-02 | クライオーセル インターナショナル,インコーポレイティド | Storage devices, especially automatically loaded and unloaded storage devices |
Cited By (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6302327B1 (en) * | 1997-06-16 | 2001-10-16 | Thermogenesis, Corp. | Method and apparatus for cryogenic storage of thermolabile products |
US20040048391A1 (en) * | 1999-08-11 | 2004-03-11 | Olson Jeffrey A. | Automated sample handling for X-ray crystallography |
US6608883B2 (en) * | 1999-08-11 | 2003-08-19 | Abbott Laboratories | Automated sample handling for X-ray crystallography |
EP1223393A2 (en) * | 2001-01-12 | 2002-07-17 | Chart, Inc. | Liquid cryogen storage container |
EP1223393A3 (en) * | 2001-01-12 | 2003-07-23 | Chart, Inc. | Liquid cryogen storage container |
WO2002077614A2 (en) * | 2001-03-23 | 2002-10-03 | Ortho-Mcneil Pharmaceutical, Inc. | Apparatus for the automation of chemical reaction kinetics studies |
US20020177956A1 (en) * | 2001-03-23 | 2002-11-28 | Johnson & Johnson | Apparatus for the automation of chemical reaction kinetics studies |
WO2002077614A3 (en) * | 2001-03-23 | 2003-03-27 | Ortho Mcneil Pharm Inc | Apparatus for the automation of chemical reaction kinetics studies |
US7045288B2 (en) | 2001-03-23 | 2006-05-16 | Ortho-Mcneil Pharmaceutical, Inc | Apparatus for the automation of chemical reaction kinetics studies |
US20040129003A1 (en) * | 2001-05-22 | 2004-07-08 | Integrated Biosystems, Inc. | Systems and methods for freezing and storing biopharmaceutical material |
US6996995B2 (en) | 2001-05-22 | 2006-02-14 | Integrated Biosystems, Inc. | Systems and methods for freezing and storing biopharmaceutical material |
US20040134203A1 (en) * | 2001-05-22 | 2004-07-15 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical material |
US6786054B2 (en) | 2001-05-22 | 2004-09-07 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical material |
US7137261B2 (en) | 2001-05-22 | 2006-11-21 | Integrated Biosystems, Inc. | Systems and methods for freezing, mixing and thawing biopharmaceutical material |
US6684646B2 (en) | 2001-05-22 | 2004-02-03 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical material |
US20050011202A1 (en) * | 2001-11-01 | 2005-01-20 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing, transporting and thawing biopharmacuetical material |
US6945056B2 (en) | 2001-11-01 | 2005-09-20 | Integrated Biosystems, Inc. | Systems and methods for freezing, mixing and thawing biopharmaceutical material |
US7104074B2 (en) | 2001-11-01 | 2006-09-12 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing, transporting and thawing biopharmaceutical material |
US20070084222A1 (en) * | 2001-11-01 | 2007-04-19 | Integrated Biosystems, Inc. | Systems and methods for freezing, storing, transporting, and thawing biopharmacuetical material |
US20040006999A1 (en) * | 2001-11-01 | 2004-01-15 | Integrated Biosystems, Inc. | Systems and methods for freezing, mixing and thawing biopharmacuetical material |
US7353658B2 (en) | 2001-11-01 | 2008-04-08 | Sartorius Stedim Freeze Thaw, Inc. | Systems and methods for freezing, storing, transporting, and thawing biopharmacuetical material |
US8028532B2 (en) | 2006-03-06 | 2011-10-04 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
US8863532B2 (en) | 2006-03-06 | 2014-10-21 | Sartorius Stedim North America Inc. | Systems and methods for freezing, storing and thawing biopharmaceutical materials |
US20080050278A1 (en) * | 2006-08-25 | 2008-02-28 | Edward Francis Farina | System for automatically storing and reprocessing patient sample's in an automatic clinical analyzer |
US7641855B2 (en) | 2006-08-25 | 2010-01-05 | Siemens Healthcare Diagnostics Inc. | System for automatically storing and reprocessing patient samples in an automatic clinical analyzer |
US7540168B2 (en) * | 2006-10-20 | 2009-06-02 | Custom Biogenic Systems | Cryogenic storage container system |
WO2008070243A2 (en) * | 2006-10-20 | 2008-06-12 | Custom Biogenic Systems | Cryogenic storage container system |
US20080092581A1 (en) * | 2006-10-20 | 2008-04-24 | Cass Schumann | Cryogenic storage container system |
WO2008070243A3 (en) * | 2006-10-20 | 2008-11-13 | Custom Biogenic Systems | Cryogenic storage container system |
CN102495563A (en) * | 2011-12-31 | 2012-06-13 | 北京市红十字血液中心 | Blood intelligent control storage system and method thereof |
US9488556B2 (en) | 2012-05-16 | 2016-11-08 | M&R Automation Gmbh | Cryogenic storage system for thermolabile specimens |
EP2664881A1 (en) | 2012-05-16 | 2013-11-20 | M & R Automation GmbH | Cryogenic storage system for thermolabile specimens |
WO2013171127A1 (en) | 2012-05-16 | 2013-11-21 | M&R Automation Gmbh | Cryogenic storage system for thermolabile specimens |
CN104417908A (en) * | 2013-08-22 | 2015-03-18 | 国玺干细胞应用技术股份有限公司 | Biological product storage device with observation window |
US10661988B2 (en) | 2014-10-31 | 2020-05-26 | Tsubakimoto Chain Co. | Low temperature storage system, transport mechanism, and low temperature storage vessel |
US11788783B2 (en) | 2017-11-07 | 2023-10-17 | MVE Biological Solutions US, LLC | Cryogenic freezer |
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Also Published As
Publication number | Publication date |
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AU8253198A (en) | 1999-01-04 |
EP1012510A4 (en) | 2000-06-28 |
WO1998058216A1 (en) | 1998-12-23 |
JP2002511827A (en) | 2002-04-16 |
EP1012510A1 (en) | 2000-06-28 |
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