US8834449B2 - Mixing syringe - Google Patents
Mixing syringe Download PDFInfo
- Publication number
- US8834449B2 US8834449B2 US13/385,627 US201213385627A US8834449B2 US 8834449 B2 US8834449 B2 US 8834449B2 US 201213385627 A US201213385627 A US 201213385627A US 8834449 B2 US8834449 B2 US 8834449B2
- Authority
- US
- United States
- Prior art keywords
- syringe
- liquid
- disc
- hole
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active, expires
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Surgical Instruments (AREA)
Abstract
Description
Claims (18)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/385,627 US8834449B2 (en) | 2012-01-23 | 2012-02-28 | Mixing syringe |
EP13741261.5A EP2806921A4 (en) | 2012-01-23 | 2013-01-22 | Mixing syringe |
JP2014553517A JP6320301B2 (en) | 2012-01-23 | 2013-01-22 | Mixing syringe |
CN201380004332.0A CN104080497B (en) | 2012-01-23 | 2013-01-22 | mixing syringe |
PCT/US2013/022561 WO2013112474A1 (en) | 2012-01-23 | 2013-01-22 | Mixing syringe |
US14/283,901 US9751056B2 (en) | 2012-01-23 | 2014-05-21 | Mixing syringe |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261632263P | 2012-01-23 | 2012-01-23 | |
US13/385,627 US8834449B2 (en) | 2012-01-23 | 2012-02-28 | Mixing syringe |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/022561 Continuation-In-Part WO2013112474A1 (en) | 2012-01-23 | 2013-01-22 | Mixing syringe |
Publications (2)
Publication Number | Publication Date |
---|---|
US20130226148A1 US20130226148A1 (en) | 2013-08-29 |
US8834449B2 true US8834449B2 (en) | 2014-09-16 |
Family
ID=48873839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/385,627 Active 2032-04-08 US8834449B2 (en) | 2012-01-23 | 2012-02-28 | Mixing syringe |
Country Status (5)
Country | Link |
---|---|
US (1) | US8834449B2 (en) |
EP (1) | EP2806921A4 (en) |
JP (1) | JP6320301B2 (en) |
CN (1) | CN104080497B (en) |
WO (1) | WO2013112474A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140254303A1 (en) * | 2012-01-23 | 2014-09-11 | Merit Medical Systems, Inc. | Mixing syringe |
US20160184528A1 (en) * | 2013-09-06 | 2016-06-30 | Terumo Kabushiki Kaisha | Syringe barrel and mold for injection molding |
US10569240B2 (en) | 2015-01-09 | 2020-02-25 | Drybev International, Inc. | Container system with mixing blade |
US10632261B2 (en) | 2018-08-22 | 2020-04-28 | Aurim, LLC | Self-admixing disposable hypodermic needle |
US11771841B2 (en) | 2020-12-23 | 2023-10-03 | Tolmar International Limited | Systems and methods for mixing syringe valve assemblies |
US11904143B2 (en) | 2017-06-08 | 2024-02-20 | Amgen Inc. | Torque driven drug delivery device |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3088040A4 (en) * | 2013-12-27 | 2017-09-13 | HI-LEX Corporation | Medical device |
KR101576809B1 (en) * | 2014-07-15 | 2015-12-14 | (주)연우 | A Syringe type vessel having mixed two-type materials |
US10251516B2 (en) * | 2015-01-09 | 2019-04-09 | Drybev International, Inc. | Container with mixing blade |
US10568462B2 (en) * | 2015-01-09 | 2020-02-25 | Drybev International, Inc. | Container with mixing blade |
US20160198906A1 (en) * | 2015-01-09 | 2016-07-14 | Drybev International, Inc. | Container with mixing blade |
KR20170021017A (en) * | 2015-08-17 | 2017-02-27 | 휴젤(주) | Syringe |
KR101672716B1 (en) * | 2015-08-24 | 2016-11-16 | 경상대학교산학협력단 | Mechanical syring assembly unit with patterned surface for mixing improvement |
CN109394537A (en) * | 2018-12-03 | 2019-03-01 | 四川大学华西第二医院 | A kind of pre-filled pressure equilibrium syringe |
DE102018131268B4 (en) * | 2018-12-07 | 2021-11-25 | Heraeus Medical Gmbh | Device for mixing a bone cement with a cavity for monomer transfer |
KR102608679B1 (en) * | 2023-04-14 | 2023-12-01 | (주)풍림파마텍 | Syringe having pressure reduction structure plunger |
Citations (168)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2514454A (en) | 1946-04-25 | 1950-07-11 | Union Switch & Signal Co | Traffic protection apparatus |
US3493503A (en) * | 1967-05-19 | 1970-02-03 | Haematronics Inc | Method of producing a protein-free fluid |
US3548825A (en) | 1967-08-22 | 1970-12-22 | Joseph Denman Shaw | Combination mixing and injecting medical syringe |
US3570486A (en) | 1968-10-14 | 1971-03-16 | Horizon Ind Ltd | Mixing syringe |
US3606094A (en) | 1969-06-05 | 1971-09-20 | Peter B Mills | Mixing and dispensing syringe |
US3661265A (en) * | 1970-07-27 | 1972-05-09 | Contemporary Research And Dev | Serum separator type container |
US3724077A (en) | 1971-11-26 | 1973-04-03 | Unitek Corp | Mixing syringe |
US3889674A (en) | 1973-11-30 | 1975-06-17 | Constabile A Cilento | Mixing syringe |
US4031892A (en) | 1974-07-18 | 1977-06-28 | Ampoules Corporation | Two-chamber mixing syringe |
US4041945A (en) | 1976-06-07 | 1977-08-16 | Guiney Aeneas C | Mixing syringe |
US4116240A (en) | 1977-03-11 | 1978-09-26 | Guiney Aeneas C | Mixing syringe |
US4412836A (en) * | 1979-04-27 | 1983-11-01 | The West Company, Incorporated | Syringe assembly |
US4435507A (en) * | 1980-07-08 | 1984-03-06 | Stenkvist Bjoern G | Process and device for preparation of cell samples for cytological tests |
US4437858A (en) * | 1978-01-16 | 1984-03-20 | Ty Perla J | Separator disc and hypodermic syringe incorporating the same and method |
US4698299A (en) | 1985-02-19 | 1987-10-06 | The Liposome Company, Inc. | Lipid-dependent diagnostic assays |
US4751921A (en) * | 1985-10-21 | 1988-06-21 | University Of Iowa Research Foundation | Bone cement syringe |
US4776704A (en) | 1986-12-15 | 1988-10-11 | Dentsply Research & Development Corp. | Mixing and dispensing syringe |
US4981468A (en) * | 1989-02-17 | 1991-01-01 | Eli Lilly And Company | Delivery device for orally administered therapeutic agents |
US5002537A (en) | 1989-10-23 | 1991-03-26 | Gte Products Corporation | Hypodermic syringe |
US5069670A (en) | 1989-05-17 | 1991-12-03 | Arzneimittel Gmbh Apotheker Vetter & Co. | Hypodermic syringe |
WO1992004926A1 (en) | 1990-09-21 | 1992-04-02 | Novo Nordisk A/S | Adaptor top |
US5122117A (en) | 1990-06-05 | 1992-06-16 | Habley Medical Technology Corp. | Component mixing syringe |
US5139490A (en) | 1989-07-27 | 1992-08-18 | Arzneimittel Gmbh Apotheker Vetter & Co. | Hypodermic syringe |
US5244465A (en) | 1988-10-19 | 1993-09-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Reusable injection device for distributing a preselected dose |
US5298023A (en) | 1991-03-08 | 1994-03-29 | Habley Medical Technology Corporation | Multiple pharmaceutical dispenser with accumulator |
US5308340A (en) | 1989-06-05 | 1994-05-03 | Eli Lilly And Company | Multiple dose injection pen |
US5320603A (en) | 1991-08-21 | 1994-06-14 | Arzneimitel Gmbh Apotheker Vetter & Co. | Hypodermic syringe for lyophilized medicament |
US5360410A (en) | 1991-01-16 | 1994-11-01 | Senetek Plc | Safety syringe for mixing two-component medicaments |
US5372029A (en) | 1990-09-22 | 1994-12-13 | Brandes; Bernd | Method of monitoring the quality of an object or state |
EP0513128B1 (en) | 1990-01-22 | 1995-07-19 | Novo Nordisk A/S | Apparatus for mixing and injecting a medicine |
US5435076A (en) | 1992-04-21 | 1995-07-25 | Pharmacia Aktiebolag | Injection device |
US5501673A (en) | 1992-04-21 | 1996-03-26 | Pharmacia Ab | Injection cartridge |
US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
US5542411A (en) | 1989-11-01 | 1996-08-06 | Novo Nordisk A/S | Manually operated dispenser for dispensing a predetermined amount of powdered substance |
US5549575A (en) | 1994-09-13 | 1996-08-27 | Becton Dickinson And Company | Cartridge retainer assembly for medication delivery pen |
US5549561A (en) | 1992-04-21 | 1996-08-27 | Pharmacia Ab | Injection cartridge arrangement |
US5554134A (en) | 1990-09-21 | 1996-09-10 | Novo Nordisk A/S | Cap for an ampoule of an injection unit |
US5592866A (en) | 1992-03-25 | 1997-01-14 | Sher; Arieh | Rotary piston driving mechanism |
US5626566A (en) | 1991-10-18 | 1997-05-06 | Novo Nordisk A/S | Large dose pen |
US5716338A (en) | 1993-10-20 | 1998-02-10 | Pharmacia & Upjohn Aktiebolag | Dual-chamber type injection cartridge with bypass connection |
US5725500A (en) | 1995-06-02 | 1998-03-10 | Eli Lilly And Company | Containers for liquid medicaments |
US5725508A (en) | 1994-06-22 | 1998-03-10 | Becton Dickinson And Company | Quick connect medication delivery pen |
EP0829268A3 (en) | 1996-09-17 | 1998-04-08 | Becton, Dickinson and Company | Non-floatable insulin cartridge holder for medication delivery pen |
US5785682A (en) | 1995-03-22 | 1998-07-28 | Abbott Laboratories | Pre-filled syringe drug delivery system |
US5785692A (en) | 1992-07-06 | 1998-07-28 | Abbott Laboratories | Safety cannula |
US5788670A (en) | 1994-12-22 | 1998-08-04 | Schott Glas | Dual chamber prefillable syringe and a method for the assembly and filling of same |
US5820602A (en) | 1995-09-08 | 1998-10-13 | Visionary Medical Products, Inc. | Pen-type injector drive mechanism |
US5823998A (en) | 1994-08-24 | 1998-10-20 | Eli Lilly Japan Kabushiki Kaisha | Injection apparatus |
US5891087A (en) | 1996-03-15 | 1999-04-06 | Takeda Chemical Industries, Ltd. | Mixing syringe |
US6036675A (en) | 1999-02-03 | 2000-03-14 | Specialized Health Products, Inc. | Safety sterile cartride unit apparatus and methods |
US6106501A (en) | 1995-11-09 | 2000-08-22 | Disetronic Licensing Ag | Injection device |
US6203529B1 (en) | 1997-11-19 | 2001-03-20 | B D Medico | Needle arrangement |
US6241709B1 (en) | 1994-05-30 | 2001-06-05 | B D Medico S.A.R.L. | Injection device |
US6277097B1 (en) | 1997-03-25 | 2001-08-21 | Novo Nordisk A/S | Injection system |
US6319225B1 (en) | 1998-03-19 | 2001-11-20 | Nihon Chemical Research Co., Ltd. | Injection syringe including device for preparation of injection |
US6331173B1 (en) | 1999-04-20 | 2001-12-18 | Pharmacia Ab | Device for displacing a member in a container |
US20010053894A1 (en) | 2000-05-18 | 2001-12-20 | Soren Steenfeldt-Jensen | Dose display for injection device |
US20020033367A1 (en) * | 1996-09-25 | 2002-03-21 | Baxter International Inc. | Method and apparatus for filtering suspensions of medical and biological fluids or the like |
US6419656B1 (en) | 1999-03-19 | 2002-07-16 | Arzneimittel Gmbh Apotheker Vetter & Ravensburg | Medical syringe with braked step-advance plunger |
US20020173752A1 (en) | 2000-02-16 | 2002-11-21 | Polzin U1F | Method for reconstituting an injection liquid and an injection appliance for carrying out such a method |
US20030032935A1 (en) | 2001-08-10 | 2003-02-13 | Scimed Life Systems, Inc. | Packages facilitating convenient mixing and delivery of liquids |
US6582404B1 (en) | 1999-09-16 | 2003-06-24 | Nna/S | Dose setting limiter |
US6582408B1 (en) | 1998-07-08 | 2003-06-24 | Thomas Buch-Rasmussen | Medical device |
US6645179B1 (en) | 1999-07-06 | 2003-11-11 | Nihon Chemical Research Co., Ltd. | Injection syringe |
US6679248B2 (en) | 2000-07-27 | 2004-01-20 | Ing. Erich Pfeiffer Gmbh | Discharge apparatus for media |
US20040092883A1 (en) | 2002-10-23 | 2004-05-13 | Casey Thomas V. | Mixing and delivery of therapeutic compositions |
FR2847887A1 (en) | 2002-12-02 | 2004-06-04 | Valois Sas | Container for two fluid products to be mixed before dispensing has two receptacles separated by sliding plugs |
US20040108339A1 (en) | 2002-08-29 | 2004-06-10 | Hansen Michael Ejstrup | Frontloaded injection device |
US20040158226A1 (en) * | 2003-02-07 | 2004-08-12 | Genoptix, Inc. | Syringe tissue sieve |
US6793646B1 (en) | 1999-04-16 | 2004-09-21 | Becton Dickinson And Company | Pen style injector with automated substance combining feature |
US20040186441A1 (en) | 2001-07-30 | 2004-09-23 | Roney Graf | Connecting casing sections of an administering apparatus for administering, in doses, a product which can be delivered |
US6817987B2 (en) * | 2001-08-18 | 2004-11-16 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Mixing hypodermic syringe |
US20050049550A1 (en) | 2003-09-03 | 2005-03-03 | Fritz Kirchhofer | Mixing device for multiple-chamber ampoule |
US6899698B2 (en) | 2000-03-24 | 2005-05-31 | Bernard Sams | One-way clutch mechanisms and injector devices |
DE10356335A1 (en) | 2003-11-28 | 2005-06-23 | Eric Schliemann | Syringe for medical use for mixing two or more separate components has cylinder containing several pistons with components trapped in spaces between them and released through bypass channels |
US20050154352A1 (en) | 2002-07-16 | 2005-07-14 | Thomas Gurtner | Administration device comprising a plunger rod with a return lock |
US20050177114A1 (en) | 2002-08-29 | 2005-08-11 | Reto Michel | Dosage displaying device |
US20050261634A1 (en) | 2002-09-24 | 2005-11-24 | Anders Karlsson | Injecting device |
DE102004055298A1 (en) | 2004-11-16 | 2006-05-24 | Tecpharma Licensing Ag | Device for mixing injected medicine comprises an ampoule sleeve, a mixing sleeve, an abutment and a guiding unit having a power transmission structure which converts a linear into a rotary movement |
US20060111666A1 (en) | 2004-09-02 | 2006-05-25 | Edgar Hommann | Auto-pen for a two-chamber ampoule |
US7081108B2 (en) | 2000-12-22 | 2006-07-25 | Dca Design International Limited | Pen-type injector having holding mechanism for medicament cartridge |
WO2006079898A1 (en) | 2005-01-25 | 2006-08-03 | Pharmacia Corporation | Injection device for administering a medication liquid |
US20060178644A1 (en) | 2004-12-03 | 2006-08-10 | Reynolds David L | Pharmaceutical cartridge assembly and method of filling same |
US7101354B2 (en) | 2004-05-03 | 2006-09-05 | Infusive Technologies, Llc | Mixing syringe with and without flush |
US20060254788A1 (en) | 2005-04-20 | 2006-11-16 | Eugen Bucher | Drive and/or dose metering module with an anti-rotation stop |
US20060258988A1 (en) | 2003-11-03 | 2006-11-16 | Joachim Keitel | Injection device |
US20070027430A1 (en) | 2003-12-18 | 2007-02-01 | Edgar Hommann | Trigger-activatable injection device |
US20070060877A1 (en) | 2005-08-13 | 2007-03-15 | Stefan Bassarab | Dual chamber container for lyophilization, process for the filling up and use thereof |
US20070060875A1 (en) | 2005-08-13 | 2007-03-15 | Stefan Bassarab | Dual chamber container without by-pass in the cylindrical body |
US20070129673A1 (en) | 2005-08-13 | 2007-06-07 | Stefan Bassarab | Dual chamber container and process for its filling up |
US20070163366A1 (en) | 2006-01-19 | 2007-07-19 | Jeong Sung-Young | Device and method for pre-treating and injecting liquid specimen |
US20070197975A1 (en) | 2004-08-25 | 2007-08-23 | Stefan Burren | Dose Metering Mechanism with Sequence Control |
US20080071226A1 (en) | 2006-01-17 | 2008-03-20 | Ulrich Moser | Extractable Dose Setting Knob |
EP1923085A1 (en) | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
US20080126102A1 (en) | 2006-11-24 | 2008-05-29 | Fujitsu Limited | Decoding apparatus and decoding method |
US7402150B2 (en) | 2005-09-05 | 2008-07-22 | Jcr Pharmaceuticals Co., Ltd. | Injection device |
US20080300550A1 (en) | 2007-06-04 | 2008-12-04 | Becton, Dickinson And Company | Positive displacement stopper for a pre-filled syringe |
US20090137964A1 (en) | 2005-05-31 | 2009-05-28 | Novo Nordisk A/S | Injection device with visual end-of-content indication |
US20090157041A1 (en) | 2001-09-12 | 2009-06-18 | Pettis Ronald J | Microneedel-based pen device for drug delivery and method for using same |
US20090209920A1 (en) | 2006-05-18 | 2009-08-20 | Novo Nordisk A/S | Injection Device with Mode Locking Means |
US20090247985A1 (en) | 2008-03-25 | 2009-10-01 | Cook Incorporated | Embolic particle mixing syringe |
US20090254027A1 (en) | 2006-03-10 | 2009-10-08 | Novo Nordisk A/S | Injection Device and a Method of Changing a Cartridge in the Device |
WO2009141005A1 (en) | 2008-05-20 | 2009-11-26 | Tecpharma Licensing Ag | Device for administering an injectable product comprising a residual amount display |
WO2010003262A2 (en) | 2008-07-09 | 2010-01-14 | Tecpharma Licensing Ag | Two-chamber ampoule mixing safeguard |
US20100030551A1 (en) | 2008-07-31 | 2010-02-04 | Ark Wendy S | Jargon translation in an instant messaging environment |
US20100036320A1 (en) | 2008-08-05 | 2010-02-11 | Cox Janice L | Multiple dosage injector |
US20100069845A1 (en) | 2005-12-02 | 2010-03-18 | Owen Mumford, Ltd. | Injection method and apparatus |
US7686782B2 (en) | 2004-08-06 | 2010-03-30 | Tecpharma Licensing Ag | Multi-chamber ampoule with bypass and piston seal |
US20100082013A1 (en) | 2008-09-30 | 2010-04-01 | Tyco Healthcare Group Lp | Diluent/Medication Mixing Syringe Assembly |
US20100087799A1 (en) | 2007-04-05 | 2010-04-08 | Sofia Galbraith | Method for administering a fluid active substance from a multi-chamber ampoule |
US7749200B2 (en) | 2002-07-17 | 2010-07-06 | Tecpharma Licensing Ag | Administration device comprising a priming function |
US20100185156A1 (en) * | 2007-06-13 | 2010-07-22 | Pervasis Therapeutics, Inc. | Methods and Devices for Minimally-Invasive Delivery of Cell-Containing Flowable Compositions |
US7771398B2 (en) | 2005-01-18 | 2010-08-10 | Wockhardt Ltd. | Pen shaped medication injection devices |
WO2010105376A1 (en) | 2009-03-20 | 2010-09-23 | Tecpharma Licensing Ag | Administering apparatus having exchangeable product unit |
US7811263B2 (en) | 2005-05-24 | 2010-10-12 | Tecpharma Licensing Ag | Dose metering mechanism for an injection device |
US20100262074A1 (en) | 2007-06-14 | 2010-10-14 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule |
US20100274198A1 (en) | 2008-08-18 | 2010-10-28 | Haselmeler Gmbh | Injection device |
US7828172B2 (en) | 2003-07-18 | 2010-11-09 | Valois S.A.S. | Dose indicator for fluid product dispensing device |
US7850662B2 (en) | 2003-03-03 | 2010-12-14 | Sanofi-Aventis Deutschland Gmbh | Drive mechanisms suitable for use in drug delivery devices |
US20100323322A1 (en) | 2007-02-09 | 2010-12-23 | Ultradent Products, Inc | Syringe-in-Syringe Hollow Inner Barrel/Plunger With Integral Seal and Rupturable Membrane and Related Kits, Systems and Methods |
US20100327007A1 (en) | 2007-11-22 | 2010-12-30 | Jonas Fransson | Method and device for the serial ejection of two fluids comprising a spacer |
US20110060274A1 (en) | 2007-12-19 | 2011-03-10 | Sanofi-Aventis Deutschland Gmbh | Two-chamber injection device having gas-permeable membrane |
US7918832B2 (en) | 2003-04-10 | 2011-04-05 | Dca Design International Ltd. | Drive mechanisms suitable for use in drug delivery devices |
KR20110041826A (en) | 2009-10-16 | 2011-04-22 | 조희민 | Syringe for mixing of materials separate kept |
US20110100921A1 (en) * | 2008-05-17 | 2011-05-05 | Hans-Werner Heinrich | Device for Separating Particles in and from Liquids and Use of Said Device in Biotechnology, Biological Research, Diagnostics and the Treatment of Diseases |
US20110152822A1 (en) | 2008-05-24 | 2011-06-23 | Annette Drunk | Ampoule comprising an ampoule holder |
US7967779B2 (en) | 2004-08-02 | 2011-06-28 | Bertron Kim W | Powder and liquid mixing syringe |
US20110196310A1 (en) | 2008-09-18 | 2011-08-11 | Becton, Dickinson And Company | Medical injector with ratcheting plunger |
US20110201999A1 (en) | 2008-09-18 | 2011-08-18 | Becton, Dickinson And Company | Needle mounting feature for ensuring proper reconstitution sequence |
US20110224622A1 (en) | 2008-09-09 | 2011-09-15 | Shl Group Ab | Medicament Delivery Device |
US20110230827A1 (en) | 2008-05-24 | 2011-09-22 | Kevin Mori | Mixing device for a two-chamber ampoule |
WO2011131775A1 (en) | 2010-04-23 | 2011-10-27 | Sanofi-Aventis Deutschland Gmbh | Coded cartridge holder system for a fluid delivery device |
WO2011131779A1 (en) | 2010-04-23 | 2011-10-27 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and drug reservoir with mechanical coding mechanism |
US8075515B2 (en) | 2007-07-06 | 2011-12-13 | Lts Lohmann Therapie-Systeme Ag | Disposable injector with at least one compression bar and a closure cap |
WO2011154488A1 (en) | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with drive member having indication elements |
US8092422B2 (en) | 2007-06-14 | 2012-01-10 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule with attachment |
WO2012010832A1 (en) | 2010-07-20 | 2012-01-26 | Future Injection Technologies Limited | Injection device |
US20120041366A1 (en) | 2008-09-18 | 2012-02-16 | Becton, Dickinson And Company | Medical injector with dose knob activation for automated reconstitution |
US20120046613A1 (en) | 2008-12-23 | 2012-02-23 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device with Piston Rod Carrying Dose Markings |
US20120078195A1 (en) | 2009-03-31 | 2012-03-29 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device body |
US8152766B2 (en) | 2006-08-18 | 2012-04-10 | Shl Group Ab | Device for delivering medicament encompassing a pressure release mechanism |
US20120095413A1 (en) | 2008-12-12 | 2012-04-19 | Sanofi-Aventis Deutschland Gmbh | Drive Mechanism for a Medication Delivery Device and Medication Delivery Device |
US20120130316A1 (en) | 2009-03-05 | 2012-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device |
US8187233B2 (en) | 2008-05-02 | 2012-05-29 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US20120136315A1 (en) | 2009-06-05 | 2012-05-31 | Shl Group Ab | Medicament Delivery Device |
US20120136298A1 (en) | 2009-06-04 | 2012-05-31 | Novo Nordisk Healthcare A/G | Mixing device with piston coupling arrangement |
US20120136306A1 (en) | 2009-03-24 | 2012-05-31 | Istvan Bartha | Device for Delivering Liquid Medicament |
WO2012072568A1 (en) | 2010-11-29 | 2012-06-07 | Sanofi-Aventis Deutschland Gmbh | Automatic delivery device with triggering mechanism |
WO2012085017A2 (en) | 2010-12-22 | 2012-06-28 | Sanofi-Aventis Deutschland Gmbh | Dedicated cartridge |
US20120172816A1 (en) | 2006-11-17 | 2012-07-05 | Malcolm Boyd | Drive Mechanisms Suitable for Use in Drug Delivery Devices |
US20120209171A1 (en) | 2007-09-27 | 2012-08-16 | Becton, Dickinson And Company | Cartridge for powder and liquid drug |
US8246577B2 (en) | 2006-08-14 | 2012-08-21 | Tecpharma Licensing Ag | Injection device with claw-type lock |
WO2012128699A1 (en) | 2011-03-24 | 2012-09-27 | Shl Group Ab | Medicament delivery device |
EP2514454A1 (en) | 2011-04-21 | 2012-10-24 | Sanofi-Aventis Deutschland GmbH | Dedicated connector |
US8298175B2 (en) | 2008-02-11 | 2012-10-30 | Tecpharma Licensing Ag | Administering device with blockable actuation element |
US20120283646A1 (en) | 2009-09-30 | 2012-11-08 | Sanofi-Aventis Deutschland Gmbh | Drug delivery system, drug delivery device, needle assembly and method for priming |
WO2012152666A1 (en) | 2011-05-06 | 2012-11-15 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
US20120310168A1 (en) | 2009-09-30 | 2012-12-06 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device |
US20130018327A1 (en) | 2009-12-07 | 2013-01-17 | Sanofi-Aventis Deutschland Gmbh | Drive assembly for a drug delivery device and drug delivery device |
US8366680B2 (en) | 2008-12-12 | 2013-02-05 | Sanofi-Aventis Deutschland Gmbh | Resettable drive mechanism for a medication delivery device and medication delivery device |
US20130046245A1 (en) | 2010-02-01 | 2013-02-21 | Sanofi-Aventis Deutschland Gmbh | Cartridge holder, drug delivery device and method for securing a cartridge in a cartridge holder |
WO2013033227A2 (en) | 2011-08-29 | 2013-03-07 | Nps Pharmaceuticals, Inc. | Injectable drug cartridge container |
US8398593B2 (en) | 2008-02-29 | 2013-03-19 | Tecpharma Licensing Ag | Brake for injection devices |
WO2013043861A2 (en) | 2011-09-20 | 2013-03-28 | Glucago Llc D/B/A Lyogo | Reconstitution device |
US8414541B2 (en) | 2005-02-28 | 2013-04-09 | Leonard Morris Spofforth | Hypodermic syringe mechanism |
US20130096513A1 (en) | 2010-02-17 | 2013-04-18 | Sanofi-Aventis Deutschland Gmbh | Automatic injection device with torsional spring |
US20130131605A1 (en) | 2010-06-11 | 2013-05-23 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and drug delivery device |
US20130218098A1 (en) | 2010-06-03 | 2013-08-22 | Shl Group Ab | Medicament Delivery Device |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07136264A (en) * | 1993-11-19 | 1995-05-30 | Nissho Corp | Two-components mixing prefilled injector |
US5522804A (en) * | 1994-02-15 | 1996-06-04 | Lynn; Lawrence A. | Aspiration, mixing, and injection syringe |
US5685846A (en) * | 1995-02-27 | 1997-11-11 | Schott Parenta Systems, Inc. | Dual chamber internal by-pass syringe assembly |
US20080045889A1 (en) * | 2004-07-21 | 2008-02-21 | Gerondale Scott J | Botoxo Needle Injector |
-
2012
- 2012-02-28 US US13/385,627 patent/US8834449B2/en active Active
-
2013
- 2013-01-22 EP EP13741261.5A patent/EP2806921A4/en not_active Withdrawn
- 2013-01-22 CN CN201380004332.0A patent/CN104080497B/en not_active Expired - Fee Related
- 2013-01-22 WO PCT/US2013/022561 patent/WO2013112474A1/en active Application Filing
- 2013-01-22 JP JP2014553517A patent/JP6320301B2/en active Active
Patent Citations (197)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2514454A (en) | 1946-04-25 | 1950-07-11 | Union Switch & Signal Co | Traffic protection apparatus |
US3493503A (en) * | 1967-05-19 | 1970-02-03 | Haematronics Inc | Method of producing a protein-free fluid |
US3548825A (en) | 1967-08-22 | 1970-12-22 | Joseph Denman Shaw | Combination mixing and injecting medical syringe |
US3570486A (en) | 1968-10-14 | 1971-03-16 | Horizon Ind Ltd | Mixing syringe |
US3606094A (en) | 1969-06-05 | 1971-09-20 | Peter B Mills | Mixing and dispensing syringe |
US3661265A (en) * | 1970-07-27 | 1972-05-09 | Contemporary Research And Dev | Serum separator type container |
US3724077A (en) | 1971-11-26 | 1973-04-03 | Unitek Corp | Mixing syringe |
US3889674A (en) | 1973-11-30 | 1975-06-17 | Constabile A Cilento | Mixing syringe |
US4031892A (en) | 1974-07-18 | 1977-06-28 | Ampoules Corporation | Two-chamber mixing syringe |
US4041945A (en) | 1976-06-07 | 1977-08-16 | Guiney Aeneas C | Mixing syringe |
US4116240A (en) | 1977-03-11 | 1978-09-26 | Guiney Aeneas C | Mixing syringe |
US4437858A (en) * | 1978-01-16 | 1984-03-20 | Ty Perla J | Separator disc and hypodermic syringe incorporating the same and method |
US4412836A (en) * | 1979-04-27 | 1983-11-01 | The West Company, Incorporated | Syringe assembly |
US4435507A (en) * | 1980-07-08 | 1984-03-06 | Stenkvist Bjoern G | Process and device for preparation of cell samples for cytological tests |
US4698299A (en) | 1985-02-19 | 1987-10-06 | The Liposome Company, Inc. | Lipid-dependent diagnostic assays |
US4751921A (en) * | 1985-10-21 | 1988-06-21 | University Of Iowa Research Foundation | Bone cement syringe |
US4776704A (en) | 1986-12-15 | 1988-10-11 | Dentsply Research & Development Corp. | Mixing and dispensing syringe |
US5244465A (en) | 1988-10-19 | 1993-09-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Reusable injection device for distributing a preselected dose |
US4981468A (en) * | 1989-02-17 | 1991-01-01 | Eli Lilly And Company | Delivery device for orally administered therapeutic agents |
US5069670A (en) | 1989-05-17 | 1991-12-03 | Arzneimittel Gmbh Apotheker Vetter & Co. | Hypodermic syringe |
US5308340A (en) | 1989-06-05 | 1994-05-03 | Eli Lilly And Company | Multiple dose injection pen |
US5139490A (en) | 1989-07-27 | 1992-08-18 | Arzneimittel Gmbh Apotheker Vetter & Co. | Hypodermic syringe |
US5002537A (en) | 1989-10-23 | 1991-03-26 | Gte Products Corporation | Hypodermic syringe |
US5542411A (en) | 1989-11-01 | 1996-08-06 | Novo Nordisk A/S | Manually operated dispenser for dispensing a predetermined amount of powdered substance |
EP0513128B1 (en) | 1990-01-22 | 1995-07-19 | Novo Nordisk A/S | Apparatus for mixing and injecting a medicine |
US5122117A (en) | 1990-06-05 | 1992-06-16 | Habley Medical Technology Corp. | Component mixing syringe |
US5693027A (en) | 1990-09-21 | 1997-12-02 | Novo Nordisk A/S | Adaptor top |
US5554134A (en) | 1990-09-21 | 1996-09-10 | Novo Nordisk A/S | Cap for an ampoule of an injection unit |
US6126646A (en) | 1990-09-21 | 2000-10-03 | Novo Nordisk A/S | Adaptor top |
WO1992004926A1 (en) | 1990-09-21 | 1992-04-02 | Novo Nordisk A/S | Adaptor top |
US5372029A (en) | 1990-09-22 | 1994-12-13 | Brandes; Bernd | Method of monitoring the quality of an object or state |
US5360410A (en) | 1991-01-16 | 1994-11-01 | Senetek Plc | Safety syringe for mixing two-component medicaments |
US5298023A (en) | 1991-03-08 | 1994-03-29 | Habley Medical Technology Corporation | Multiple pharmaceutical dispenser with accumulator |
US5320603A (en) | 1991-08-21 | 1994-06-14 | Arzneimitel Gmbh Apotheker Vetter & Co. | Hypodermic syringe for lyophilized medicament |
US5626566A (en) | 1991-10-18 | 1997-05-06 | Novo Nordisk A/S | Large dose pen |
US5592866A (en) | 1992-03-25 | 1997-01-14 | Sher; Arieh | Rotary piston driving mechanism |
US5501673A (en) | 1992-04-21 | 1996-03-26 | Pharmacia Ab | Injection cartridge |
US5549561A (en) | 1992-04-21 | 1996-08-27 | Pharmacia Ab | Injection cartridge arrangement |
US5435076A (en) | 1992-04-21 | 1995-07-25 | Pharmacia Aktiebolag | Injection device |
US5785692A (en) | 1992-07-06 | 1998-07-28 | Abbott Laboratories | Safety cannula |
US5716338A (en) | 1993-10-20 | 1998-02-10 | Pharmacia & Upjohn Aktiebolag | Dual-chamber type injection cartridge with bypass connection |
US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
US20020165500A1 (en) | 1994-05-30 | 2002-11-07 | Herbert Bechtold | Injection device |
US6241709B1 (en) | 1994-05-30 | 2001-06-05 | B D Medico S.A.R.L. | Injection device |
US5725508A (en) | 1994-06-22 | 1998-03-10 | Becton Dickinson And Company | Quick connect medication delivery pen |
US5823998A (en) | 1994-08-24 | 1998-10-20 | Eli Lilly Japan Kabushiki Kaisha | Injection apparatus |
US5549575A (en) | 1994-09-13 | 1996-08-27 | Becton Dickinson And Company | Cartridge retainer assembly for medication delivery pen |
US5788670A (en) | 1994-12-22 | 1998-08-04 | Schott Glas | Dual chamber prefillable syringe and a method for the assembly and filling of same |
US5785682A (en) | 1995-03-22 | 1998-07-28 | Abbott Laboratories | Pre-filled syringe drug delivery system |
US5725500A (en) | 1995-06-02 | 1998-03-10 | Eli Lilly And Company | Containers for liquid medicaments |
US5820602A (en) | 1995-09-08 | 1998-10-13 | Visionary Medical Products, Inc. | Pen-type injector drive mechanism |
US6106501A (en) | 1995-11-09 | 2000-08-22 | Disetronic Licensing Ag | Injection device |
US5891087A (en) | 1996-03-15 | 1999-04-06 | Takeda Chemical Industries, Ltd. | Mixing syringe |
EP0829268A3 (en) | 1996-09-17 | 1998-04-08 | Becton, Dickinson and Company | Non-floatable insulin cartridge holder for medication delivery pen |
US20020033367A1 (en) * | 1996-09-25 | 2002-03-21 | Baxter International Inc. | Method and apparatus for filtering suspensions of medical and biological fluids or the like |
US6277097B1 (en) | 1997-03-25 | 2001-08-21 | Novo Nordisk A/S | Injection system |
US6203529B1 (en) | 1997-11-19 | 2001-03-20 | B D Medico | Needle arrangement |
US6319225B1 (en) | 1998-03-19 | 2001-11-20 | Nihon Chemical Research Co., Ltd. | Injection syringe including device for preparation of injection |
US6582408B1 (en) | 1998-07-08 | 2003-06-24 | Thomas Buch-Rasmussen | Medical device |
US6036675A (en) | 1999-02-03 | 2000-03-14 | Specialized Health Products, Inc. | Safety sterile cartride unit apparatus and methods |
US6419656B1 (en) | 1999-03-19 | 2002-07-16 | Arzneimittel Gmbh Apotheker Vetter & Ravensburg | Medical syringe with braked step-advance plunger |
US6793646B1 (en) | 1999-04-16 | 2004-09-21 | Becton Dickinson And Company | Pen style injector with automated substance combining feature |
US6331173B1 (en) | 1999-04-20 | 2001-12-18 | Pharmacia Ab | Device for displacing a member in a container |
US6645179B1 (en) | 1999-07-06 | 2003-11-11 | Nihon Chemical Research Co., Ltd. | Injection syringe |
USRE41956E1 (en) | 1999-09-16 | 2010-11-23 | Novo Nordisk A/S | Dose setting limiter |
US6582404B1 (en) | 1999-09-16 | 2003-06-24 | Nna/S | Dose setting limiter |
US20020173752A1 (en) | 2000-02-16 | 2002-11-21 | Polzin U1F | Method for reconstituting an injection liquid and an injection appliance for carrying out such a method |
US6899698B2 (en) | 2000-03-24 | 2005-05-31 | Bernard Sams | One-way clutch mechanisms and injector devices |
US20010053894A1 (en) | 2000-05-18 | 2001-12-20 | Soren Steenfeldt-Jensen | Dose display for injection device |
US6679248B2 (en) | 2000-07-27 | 2004-01-20 | Ing. Erich Pfeiffer Gmbh | Discharge apparatus for media |
US7081108B2 (en) | 2000-12-22 | 2006-07-25 | Dca Design International Limited | Pen-type injector having holding mechanism for medicament cartridge |
US20040186441A1 (en) | 2001-07-30 | 2004-09-23 | Roney Graf | Connecting casing sections of an administering apparatus for administering, in doses, a product which can be delivered |
US20030032935A1 (en) | 2001-08-10 | 2003-02-13 | Scimed Life Systems, Inc. | Packages facilitating convenient mixing and delivery of liquids |
US6817987B2 (en) * | 2001-08-18 | 2004-11-16 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Mixing hypodermic syringe |
US20090157041A1 (en) | 2001-09-12 | 2009-06-18 | Pettis Ronald J | Microneedel-based pen device for drug delivery and method for using same |
US20050154352A1 (en) | 2002-07-16 | 2005-07-14 | Thomas Gurtner | Administration device comprising a plunger rod with a return lock |
US7749200B2 (en) | 2002-07-17 | 2010-07-06 | Tecpharma Licensing Ag | Administration device comprising a priming function |
US20050177114A1 (en) | 2002-08-29 | 2005-08-11 | Reto Michel | Dosage displaying device |
US20040108339A1 (en) | 2002-08-29 | 2004-06-10 | Hansen Michael Ejstrup | Frontloaded injection device |
US20050261634A1 (en) | 2002-09-24 | 2005-11-24 | Anders Karlsson | Injecting device |
US7883490B2 (en) | 2002-10-23 | 2011-02-08 | Boston Scientific Scimed, Inc. | Mixing and delivery of therapeutic compositions |
US20040092883A1 (en) | 2002-10-23 | 2004-05-13 | Casey Thomas V. | Mixing and delivery of therapeutic compositions |
FR2847887A1 (en) | 2002-12-02 | 2004-06-04 | Valois Sas | Container for two fluid products to be mixed before dispensing has two receptacles separated by sliding plugs |
US20040158226A1 (en) * | 2003-02-07 | 2004-08-12 | Genoptix, Inc. | Syringe tissue sieve |
US20120089100A1 (en) | 2003-03-03 | 2012-04-12 | Dca Design International Ltd | Pen-Type Injector |
US7918833B2 (en) | 2003-03-03 | 2011-04-05 | DCA Design International, Ltd | Pen-type injector |
EP2263721B1 (en) | 2003-03-03 | 2013-04-24 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for drug delivery device |
EP2263722B1 (en) | 2003-03-03 | 2013-04-24 | Sanofi-Aventis Deutschland GmbH | Pen-type injector with dose dial sleeve |
US20110152784A1 (en) | 2003-03-03 | 2011-06-23 | Robert Frederick Veasey | Pen-type injector |
EP1974761B1 (en) | 2003-03-03 | 2011-02-02 | DCA Design International Limited | Pen-type injector with dose dial sleeve |
US7850662B2 (en) | 2003-03-03 | 2010-12-14 | Sanofi-Aventis Deutschland Gmbh | Drive mechanisms suitable for use in drug delivery devices |
US7918832B2 (en) | 2003-04-10 | 2011-04-05 | Dca Design International Ltd. | Drive mechanisms suitable for use in drug delivery devices |
US7828172B2 (en) | 2003-07-18 | 2010-11-09 | Valois S.A.S. | Dose indicator for fluid product dispensing device |
US20070270739A1 (en) | 2003-09-03 | 2007-11-22 | Techpharma Licensing Ag | Mixing Device for Multiple-Chamber Ampoule |
US20050049550A1 (en) | 2003-09-03 | 2005-03-03 | Fritz Kirchhofer | Mixing device for multiple-chamber ampoule |
US20060258988A1 (en) | 2003-11-03 | 2006-11-16 | Joachim Keitel | Injection device |
DE10356335A1 (en) | 2003-11-28 | 2005-06-23 | Eric Schliemann | Syringe for medical use for mixing two or more separate components has cylinder containing several pistons with components trapped in spaces between them and released through bypass channels |
US20070027430A1 (en) | 2003-12-18 | 2007-02-01 | Edgar Hommann | Trigger-activatable injection device |
US7101354B2 (en) | 2004-05-03 | 2006-09-05 | Infusive Technologies, Llc | Mixing syringe with and without flush |
US7967779B2 (en) | 2004-08-02 | 2011-06-28 | Bertron Kim W | Powder and liquid mixing syringe |
US7686782B2 (en) | 2004-08-06 | 2010-03-30 | Tecpharma Licensing Ag | Multi-chamber ampoule with bypass and piston seal |
US20070197975A1 (en) | 2004-08-25 | 2007-08-23 | Stefan Burren | Dose Metering Mechanism with Sequence Control |
US7815598B2 (en) | 2004-09-02 | 2010-10-19 | Tecpharma Licensing Ag | Auto-pen for a two-chamber ampoule |
US20060111666A1 (en) | 2004-09-02 | 2006-05-25 | Edgar Hommann | Auto-pen for a two-chamber ampoule |
DE102004055298A1 (en) | 2004-11-16 | 2006-05-24 | Tecpharma Licensing Ag | Device for mixing injected medicine comprises an ampoule sleeve, a mixing sleeve, an abutment and a guiding unit having a power transmission structure which converts a linear into a rotary movement |
US20060178638A1 (en) | 2004-12-03 | 2006-08-10 | Reynolds David L | Device and method for pharmaceutical mixing and delivery |
US20060178644A1 (en) | 2004-12-03 | 2006-08-10 | Reynolds David L | Pharmaceutical cartridge assembly and method of filling same |
US7771398B2 (en) | 2005-01-18 | 2010-08-10 | Wockhardt Ltd. | Pen shaped medication injection devices |
WO2006079898A1 (en) | 2005-01-25 | 2006-08-03 | Pharmacia Corporation | Injection device for administering a medication liquid |
US8414541B2 (en) | 2005-02-28 | 2013-04-09 | Leonard Morris Spofforth | Hypodermic syringe mechanism |
US20060254788A1 (en) | 2005-04-20 | 2006-11-16 | Eugen Bucher | Drive and/or dose metering module with an anti-rotation stop |
US7867202B2 (en) | 2005-05-24 | 2011-01-11 | Tecpharma Licensing Ag | Threaded rod and dose setting mechanism for an injection device |
US7811263B2 (en) | 2005-05-24 | 2010-10-12 | Tecpharma Licensing Ag | Dose metering mechanism for an injection device |
US20090137964A1 (en) | 2005-05-31 | 2009-05-28 | Novo Nordisk A/S | Injection device with visual end-of-content indication |
US20070129673A1 (en) | 2005-08-13 | 2007-06-07 | Stefan Bassarab | Dual chamber container and process for its filling up |
US8002734B2 (en) | 2005-08-13 | 2011-08-23 | Boehringer Ingelheim International Gmbh | Dual chamber container and process for its filling up |
US8096971B2 (en) | 2005-08-13 | 2012-01-17 | Boehringer Ingelheim International Gmbh | Dual chamber container for lyophilization, process for the filling up and use thereof |
US20070060877A1 (en) | 2005-08-13 | 2007-03-15 | Stefan Bassarab | Dual chamber container for lyophilization, process for the filling up and use thereof |
US20070060875A1 (en) | 2005-08-13 | 2007-03-15 | Stefan Bassarab | Dual chamber container without by-pass in the cylindrical body |
US7402150B2 (en) | 2005-09-05 | 2008-07-22 | Jcr Pharmaceuticals Co., Ltd. | Injection device |
US20100069845A1 (en) | 2005-12-02 | 2010-03-18 | Owen Mumford, Ltd. | Injection method and apparatus |
US20080071226A1 (en) | 2006-01-17 | 2008-03-20 | Ulrich Moser | Extractable Dose Setting Knob |
US20070163366A1 (en) | 2006-01-19 | 2007-07-19 | Jeong Sung-Young | Device and method for pre-treating and injecting liquid specimen |
US20090254027A1 (en) | 2006-03-10 | 2009-10-08 | Novo Nordisk A/S | Injection Device and a Method of Changing a Cartridge in the Device |
US20090209920A1 (en) | 2006-05-18 | 2009-08-20 | Novo Nordisk A/S | Injection Device with Mode Locking Means |
US8246577B2 (en) | 2006-08-14 | 2012-08-21 | Tecpharma Licensing Ag | Injection device with claw-type lock |
US8152766B2 (en) | 2006-08-18 | 2012-04-10 | Shl Group Ab | Device for delivering medicament encompassing a pressure release mechanism |
EP1923085A1 (en) | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
US20120289929A1 (en) | 2006-11-17 | 2012-11-15 | Sanofi-Aventis Deutschland Gmbh | Drive Mechanisms Suitable for Use in Drug Delivery Devices |
US20120172816A1 (en) | 2006-11-17 | 2012-07-05 | Malcolm Boyd | Drive Mechanisms Suitable for Use in Drug Delivery Devices |
US20080126102A1 (en) | 2006-11-24 | 2008-05-29 | Fujitsu Limited | Decoding apparatus and decoding method |
US20100323322A1 (en) | 2007-02-09 | 2010-12-23 | Ultradent Products, Inc | Syringe-in-Syringe Hollow Inner Barrel/Plunger With Integral Seal and Rupturable Membrane and Related Kits, Systems and Methods |
US8439864B2 (en) | 2007-04-05 | 2013-05-14 | Tecpharma Licensing Ag | Device for administering fluid from a multi-chamber ampoule in incremental steps |
US20100087799A1 (en) | 2007-04-05 | 2010-04-08 | Sofia Galbraith | Method for administering a fluid active substance from a multi-chamber ampoule |
US20080300550A1 (en) | 2007-06-04 | 2008-12-04 | Becton, Dickinson And Company | Positive displacement stopper for a pre-filled syringe |
US20100185156A1 (en) * | 2007-06-13 | 2010-07-22 | Pervasis Therapeutics, Inc. | Methods and Devices for Minimally-Invasive Delivery of Cell-Containing Flowable Compositions |
US20120118139A1 (en) | 2007-06-14 | 2012-05-17 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule |
US8092422B2 (en) | 2007-06-14 | 2012-01-10 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule with attachment |
US8092421B2 (en) | 2007-06-14 | 2012-01-10 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule |
US20120078171A1 (en) | 2007-06-14 | 2012-03-29 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule with attachment |
US20100262074A1 (en) | 2007-06-14 | 2010-10-14 | Sanofi-Aventis Deutschland Gmbh | Dual-chamber carpule |
US8075515B2 (en) | 2007-07-06 | 2011-12-13 | Lts Lohmann Therapie-Systeme Ag | Disposable injector with at least one compression bar and a closure cap |
US20120209171A1 (en) | 2007-09-27 | 2012-08-16 | Becton, Dickinson And Company | Cartridge for powder and liquid drug |
US20100327007A1 (en) | 2007-11-22 | 2010-12-30 | Jonas Fransson | Method and device for the serial ejection of two fluids comprising a spacer |
US20110060274A1 (en) | 2007-12-19 | 2011-03-10 | Sanofi-Aventis Deutschland Gmbh | Two-chamber injection device having gas-permeable membrane |
US8298175B2 (en) | 2008-02-11 | 2012-10-30 | Tecpharma Licensing Ag | Administering device with blockable actuation element |
US8398593B2 (en) | 2008-02-29 | 2013-03-19 | Tecpharma Licensing Ag | Brake for injection devices |
US20090247985A1 (en) | 2008-03-25 | 2009-10-01 | Cook Incorporated | Embolic particle mixing syringe |
US20130053789A1 (en) | 2008-05-02 | 2013-02-28 | Sanofi-Aventis Deutschland Gmbh | Medication Delivery Device |
US8187233B2 (en) | 2008-05-02 | 2012-05-29 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US8267900B2 (en) | 2008-05-02 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US20110100921A1 (en) * | 2008-05-17 | 2011-05-05 | Hans-Werner Heinrich | Device for Separating Particles in and from Liquids and Use of Said Device in Biotechnology, Biological Research, Diagnostics and the Treatment of Diseases |
WO2009141005A1 (en) | 2008-05-20 | 2009-11-26 | Tecpharma Licensing Ag | Device for administering an injectable product comprising a residual amount display |
US20110152822A1 (en) | 2008-05-24 | 2011-06-23 | Annette Drunk | Ampoule comprising an ampoule holder |
US20110230827A1 (en) | 2008-05-24 | 2011-09-22 | Kevin Mori | Mixing device for a two-chamber ampoule |
WO2010003262A2 (en) | 2008-07-09 | 2010-01-14 | Tecpharma Licensing Ag | Two-chamber ampoule mixing safeguard |
US20100030551A1 (en) | 2008-07-31 | 2010-02-04 | Ark Wendy S | Jargon translation in an instant messaging environment |
US20100036320A1 (en) | 2008-08-05 | 2010-02-11 | Cox Janice L | Multiple dosage injector |
US8376993B2 (en) | 2008-08-05 | 2013-02-19 | Antares Pharma, Inc. | Multiple dosage injector |
US20100274198A1 (en) | 2008-08-18 | 2010-10-28 | Haselmeler Gmbh | Injection device |
US20110224622A1 (en) | 2008-09-09 | 2011-09-15 | Shl Group Ab | Medicament Delivery Device |
US20110196310A1 (en) | 2008-09-18 | 2011-08-11 | Becton, Dickinson And Company | Medical injector with ratcheting plunger |
US20120041366A1 (en) | 2008-09-18 | 2012-02-16 | Becton, Dickinson And Company | Medical injector with dose knob activation for automated reconstitution |
US20110201999A1 (en) | 2008-09-18 | 2011-08-18 | Becton, Dickinson And Company | Needle mounting feature for ensuring proper reconstitution sequence |
US20100082013A1 (en) | 2008-09-30 | 2010-04-01 | Tyco Healthcare Group Lp | Diluent/Medication Mixing Syringe Assembly |
US20120095413A1 (en) | 2008-12-12 | 2012-04-19 | Sanofi-Aventis Deutschland Gmbh | Drive Mechanism for a Medication Delivery Device and Medication Delivery Device |
US8366680B2 (en) | 2008-12-12 | 2013-02-05 | Sanofi-Aventis Deutschland Gmbh | Resettable drive mechanism for a medication delivery device and medication delivery device |
US20120046613A1 (en) | 2008-12-23 | 2012-02-23 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device with Piston Rod Carrying Dose Markings |
US20120130316A1 (en) | 2009-03-05 | 2012-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device |
WO2010105376A1 (en) | 2009-03-20 | 2010-09-23 | Tecpharma Licensing Ag | Administering apparatus having exchangeable product unit |
US20120136306A1 (en) | 2009-03-24 | 2012-05-31 | Istvan Bartha | Device for Delivering Liquid Medicament |
US20120078195A1 (en) | 2009-03-31 | 2012-03-29 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device body |
US20120136298A1 (en) | 2009-06-04 | 2012-05-31 | Novo Nordisk Healthcare A/G | Mixing device with piston coupling arrangement |
US20120136315A1 (en) | 2009-06-05 | 2012-05-31 | Shl Group Ab | Medicament Delivery Device |
US20120283646A1 (en) | 2009-09-30 | 2012-11-08 | Sanofi-Aventis Deutschland Gmbh | Drug delivery system, drug delivery device, needle assembly and method for priming |
US20120310168A1 (en) | 2009-09-30 | 2012-12-06 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device |
KR20110041826A (en) | 2009-10-16 | 2011-04-22 | 조희민 | Syringe for mixing of materials separate kept |
US20130018327A1 (en) | 2009-12-07 | 2013-01-17 | Sanofi-Aventis Deutschland Gmbh | Drive assembly for a drug delivery device and drug delivery device |
US20130046245A1 (en) | 2010-02-01 | 2013-02-21 | Sanofi-Aventis Deutschland Gmbh | Cartridge holder, drug delivery device and method for securing a cartridge in a cartridge holder |
US20130096513A1 (en) | 2010-02-17 | 2013-04-18 | Sanofi-Aventis Deutschland Gmbh | Automatic injection device with torsional spring |
US20130211326A1 (en) | 2010-04-23 | 2013-08-15 | Sanofi-Aventis Deutschland Gmbh | Coded Cartridge Holder System for a Fluid Delivery Device |
WO2011131779A1 (en) | 2010-04-23 | 2011-10-27 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and drug reservoir with mechanical coding mechanism |
WO2011131775A1 (en) | 2010-04-23 | 2011-10-27 | Sanofi-Aventis Deutschland Gmbh | Coded cartridge holder system for a fluid delivery device |
US20130218098A1 (en) | 2010-06-03 | 2013-08-22 | Shl Group Ab | Medicament Delivery Device |
US20130190719A1 (en) | 2010-06-11 | 2013-07-25 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with drive member having indication elements |
US20130131605A1 (en) | 2010-06-11 | 2013-05-23 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and drug delivery device |
WO2011154488A1 (en) | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with drive member having indication elements |
WO2012010832A1 (en) | 2010-07-20 | 2012-01-26 | Future Injection Technologies Limited | Injection device |
WO2012072568A1 (en) | 2010-11-29 | 2012-06-07 | Sanofi-Aventis Deutschland Gmbh | Automatic delivery device with triggering mechanism |
US20130245562A1 (en) | 2010-11-29 | 2013-09-19 | Sanofi-Aventis Deutschland Gmbh | Automatic Delivery Device with Triggering Mechanism |
WO2012085017A2 (en) | 2010-12-22 | 2012-06-28 | Sanofi-Aventis Deutschland Gmbh | Dedicated cartridge |
US20130253433A1 (en) | 2010-12-22 | 2013-09-26 | James Senior | Dedicated cartridge |
WO2012128699A1 (en) | 2011-03-24 | 2012-09-27 | Shl Group Ab | Medicament delivery device |
EP2514454A1 (en) | 2011-04-21 | 2012-10-24 | Sanofi-Aventis Deutschland GmbH | Dedicated connector |
WO2012152666A1 (en) | 2011-05-06 | 2012-11-15 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
WO2013033227A2 (en) | 2011-08-29 | 2013-03-07 | Nps Pharmaceuticals, Inc. | Injectable drug cartridge container |
WO2013043861A2 (en) | 2011-09-20 | 2013-03-28 | Glucago Llc D/B/A Lyogo | Reconstitution device |
Non-Patent Citations (1)
Title |
---|
International Search Report and Written Opinion dated May 15, 2013 for PCT/US2013/022561. |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140254303A1 (en) * | 2012-01-23 | 2014-09-11 | Merit Medical Systems, Inc. | Mixing syringe |
US9751056B2 (en) * | 2012-01-23 | 2017-09-05 | Merit Medical Systems, Inc. | Mixing syringe |
US20160184528A1 (en) * | 2013-09-06 | 2016-06-30 | Terumo Kabushiki Kaisha | Syringe barrel and mold for injection molding |
US10130771B2 (en) * | 2013-09-06 | 2018-11-20 | Terumo Kabushiki Kaisha | Syringe barrel and mold for injection molding |
US10569240B2 (en) | 2015-01-09 | 2020-02-25 | Drybev International, Inc. | Container system with mixing blade |
US11904143B2 (en) | 2017-06-08 | 2024-02-20 | Amgen Inc. | Torque driven drug delivery device |
US10632261B2 (en) | 2018-08-22 | 2020-04-28 | Aurim, LLC | Self-admixing disposable hypodermic needle |
US11771841B2 (en) | 2020-12-23 | 2023-10-03 | Tolmar International Limited | Systems and methods for mixing syringe valve assemblies |
US11931559B2 (en) | 2020-12-23 | 2024-03-19 | Tolmar International Limited | Systems and methods for mixing syringe valve assemblies |
Also Published As
Publication number | Publication date |
---|---|
CN104080497A (en) | 2014-10-01 |
EP2806921A1 (en) | 2014-12-03 |
JP6320301B2 (en) | 2018-05-09 |
EP2806921A4 (en) | 2015-11-25 |
US20130226148A1 (en) | 2013-08-29 |
CN104080497B (en) | 2017-04-12 |
JP2015503999A (en) | 2015-02-05 |
WO2013112474A1 (en) | 2013-08-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8834449B2 (en) | Mixing syringe | |
US9751056B2 (en) | Mixing syringe | |
JP7389162B2 (en) | Vial transfer and injection equipment and methods | |
JP6012159B2 (en) | Contrast medium generation and delivery device | |
US20090247955A1 (en) | Microliter injector | |
JP6807742B2 (en) | Therapeutic agents delivered using catheters and pressure sources | |
US20070197954A1 (en) | Medical devices with enhanced ultrasonic visibilty | |
Shih et al. | Flow-focusing regimes for accelerated production of monodisperse drug-loadable microbubbles toward clinical-scale applications | |
CA2584638C (en) | Medical device for generating transient bubbles | |
KR101547610B1 (en) | Device and method for producing therapeutic foam | |
US11147931B2 (en) | Drug delivery device with air and backflow elimination | |
JP2021520891A (en) | How to remove gas from the reservoir | |
KR102507416B1 (en) | Syringe for Foam Dosing | |
JP2017500097A (en) | Apparatus for dispensing composition and method for dispensing composition | |
WO2015148499A1 (en) | Controlled nucleation from gas-supersaturated liquid | |
WO2009047276A1 (en) | Hypodermic needle with water-soluble obstruction for the administration of drugs and vaccines | |
US20160095604A1 (en) | Mixing Syringe | |
TW201540331A (en) | Device for delivering particles | |
JP6715854B2 (en) | Medical equipment | |
JP2018047307A (en) | Mixing device, mixing tube, medical solution injection system, and medical solution mixing method | |
JP2016084298A (en) | Emulsion for blood vessel injection, production method thereof, and device used for production thereof | |
JP6281050B2 (en) | Mixing device, mixing tube, chemical solution injection system, and method for mixing chemical solutions | |
JP2018202035A (en) | Indwelling needle and medical connector device | |
KR20200068874A (en) | Micro filter type computed tomography contrast agent automatic injector |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: IKOMED TECHNOLOGIES, INC., CANADA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:GELBART, DANIEL;MACHAN, LINDSAY S.;REEL/FRAME:028185/0145 Effective date: 20120303 |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |
|
MAFP | Maintenance fee payment |
Free format text: PAYMENT OF MAINTENANCE FEE, 4TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1551) Year of fee payment: 4 |
|
MAFP | Maintenance fee payment |
Free format text: PAYMENT OF MAINTENANCE FEE, 8TH YEAR, LARGE ENTITY (ORIGINAL EVENT CODE: M1552); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY Year of fee payment: 8 |