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Número de publicaciónUS8839798 B2
Tipo de publicaciónConcesión
Número de solicitudUS 12/421,375
Fecha de publicación23 Sep 2014
Fecha de presentación9 Abr 2009
Fecha de prioridad18 Abr 2008
También publicado comoCN102548605A, CN102548605B, EP2416832A1, US20090264739, WO2010118314A1
Número de publicación12421375, 421375, US 8839798 B2, US 8839798B2, US-B2-8839798, US8839798 B2, US8839798B2
InventoresH. Toby Markowitz, Chad Giese, Jeff Jannicke, Steven L. Waldhauser
Cesionario originalMedtronic, Inc.
Exportar citaBiBTeX, EndNote, RefMan
Enlaces externos: USPTO, Cesión de USPTO, Espacenet
System and method for determining sheath location
US 8839798 B2
Resumen
A system for determining a location of an instrument within an anatomy is provided. The system can include a first instrument, which can define at least one lumen. The system can further include a second instrument, which can be received through the at least one lumen. The system can include at least one electrode, which can be coupled to a distal end of the first instrument. The electrode can be responsive to electrical activity to generate at least one signal. The system can include a sensing unit, which can be in contact with the anatomy to sense electrical activity within the anatomy at a location near the instrument. The sensing unit can be in communication with the electrode to receive the signal. The system can further include a control module that can determine, based on the sensed electrical activity and the signal, the location of the first instrument.
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Reclamaciones(24)
What is claimed is:
1. A system for determining a location of an instrument within an anatomy comprising:
a first instrument navigable within the anatomy that defines at least one lumen, and includes a proximal end and a distal end;
a second instrument received through the at least one lumen and navigable within the anatomy relative to the first instrument;
at least one electrode coupled to the distal end of the first instrument, wherein the at least one electrode is responsive to electrical activity to generate at least one signal, wherein the at least one electrode includes a first metal portion and a second polymer portion configured to be slit such that the at least one electrode is slittable from around the second instrument, wherein the first metal portion only partially surrounds the first instrument and the second polymer portion is coupled to the first metal portion;
a sensing unit to sense electrical activity within the anatomy at a location near the at least one electrode, the sensing unit in communication with the at least one electrode to receive the at least one signal;
a control module that determines, based on the sensed electrical activity and the at least one signal, the location of the first instrument.
2. The system of claim 1, further comprising:
a first drive patch adapted to be in contact with the anatomy; and
a second drive patch adapted to be in contact with the anatomy and spaced apart from the first drive patch, the first drive patch and the second drive patch positioned at or near the location.
3. The system of claim 2, further comprising:
a first reference patch adapted to be in contact with the anatomy and spaced apart from the first drive patch and the second drive patch; and
a second reference patch adapted to be in contact with the anatomy and spaced apart from the first drive patch, the second drive patch and the first reference patch, the first reference patch and the second reference patch adapted to be positioned at or near the location.
4. The system of claim 3, wherein the sensing unit generates a voltage between the first drive patch and the second drive patch and the sensed electrical activity comprises voltages sensed between the first reference patch and the second reference patch.
5. The system of claim 4, wherein the at least one electrode of the first instrument is responsive to the voltages between the first drive patch and the second drive patch, and the at least one signal from the at least one electrode comprises at least one voltage sensed by the at least one electrode.
6. The system of claim 5, wherein based on the sensed electrical activity between the first drive patch and the second drive patch, and the at least one signal from the at least one electrode, the control module determines at least one impedance of the at least one electrode of the first instrument.
7. The system of claim 6, wherein the control module determines a position of the second instrument relative to the anatomy based on the at least one impedance of the at least one electrode of the first instrument.
8. The system of claim 4, wherein the second instrument further comprises:
at least one second instrument electrode at a distal end, the at least one second instrument electrode responsive to the voltage to generate at least one second instrument signal that indicates at least one voltage sensed by the at least one second instrument electrode; and
wherein the sensing unit is in communication with the at least one second instrument electrode to receive the at least one second instrument electrode signal, and based on the sensed electrical activity and the at least one second instrument signal, the control module determines at least one impedance of the at least one second instrument electrode of the second instrument.
9. The system of claim 8, further comprising:
a display that displays the position of the first instrument relative to the second instrument;
wherein the control module determines a position of the first instrument relative to the anatomy based on the at least one impedance of the at least one second instrument electrode of the second instrument.
10. The system of claim 1, wherein the second instrument comprises a catheter, balloon catheter, mapping catheter, basket catheter, guide wire, arthroscopic system, cardiac lead, implant or combinations thereof.
11. The system of claim 1, which the first portion and the second portion together completely surround the first instrument.
12. A system for determining a location of an instrument within an anatomy comprising:
a first electrode patch adapted to be in contact with the anatomy;
a second electrode patch adapted to be in contact with the anatomy and spaced apart from the first electrode patch;
a first instrument that is navigable within the anatomy relative to the first electrode patch and the second electrode patch, wherein the first instrument has an outer wall that defines at least one lumen and includes a distal end;
a second instrument received through the at least one lumen and moveable relative to the first instrument and wherein the second instrument is navigable within the anatomy with a second instrument electrode relative to the first instrument, the first electrode patch, and the second electrode patch;
at least one first instrument electrode coupled to the distal end of the first instrument, wherein the at least one first instrument electrode and the second instrument electrode are responsive to electrical activity to each generate at least one signal;
a sensing unit in communication with the first electrode patch and the second electrode patch to generate voltage between the first electrode patch and the second electrode patch, the sensing unit in communication with the at least one first instrument electrode of first instrument to receive the at least one signal and to determine at least one impedance of the at least one first instrument electrode of the first instrument based on the at least one signal; and a control module that determines, based on the at least one impedance of the at least one first instrument electrode of the first instrument, the location of the first instrument within the anatomy;
wherein the at least one first instrument electrode further comprises:
a metal portion that extends around a circumference of the first instrument on an inner surface; and
a polymeric band that extends around the circumference on an outer surface;
wherein the metal portion and the polymeric band are coupled through the wall of the first instrument.
13. The system of claim 12, wherein the at least one first instrument electrode further comprises:
the metal portion in communication with the sensing unit; and
the polymeric band extending from the metal portion.
14. The system of claim 13, wherein the metal portion comprises a metal electrode that does not circumscribe the circumference of the first instrument.
15. The system of claim 14, wherein the metal electrode has a shape adapted to direct a cutting instrument, the shape selected from the group comprising a triangle, diamond, trapezoid, oval, circle, rectangle and a polygon.
16. The system of claim 14, wherein the metal electrode has a shaped portion configured to position and direct a cutting tool to slit the metal electrode.
17. The system of claim 13, wherein the at least one first instrument electrode is able to be slit so as to no longer extend around the circumference of the first instrument so that the first instrument can be removed without removing the second instrument.
18. The system of claim 12, wherein the at least one first instrument electrode comprises:
the polymeric band in communication with the metal portion via a bore defined through the first instrument; and
a suitable connector coupling the metal portion to the sensing unit.
19. The system of claim 18, wherein the polymeric band is formed over the lumen of the first instrument so that during the forming of the polymeric band at least a portion of a conductive polymer comprising the polymeric band flows through the lumen to contact the metal portion.
20. The system of claim 12, wherein the first instrument defines a bore which receives a portion of the polymeric band to couple to and enable electrical communication between the metal portion and the polymeric band.
21. The system of claim 20, wherein the metal band portion is internally positioned relative to the polymeric band and both are concentric about a center point of the first instrument.
22. A method for determining a location of an instrument within an anatomy comprising:
providing a first instrument that includes at least one lumen and at least one electrode substantially circumscribing the at least one lumen, wherein the at least one electrode is configured to be slit;
inserting a second instrument into the at least one lumen;
inserting the second instrument and at least a portion of the first instrument into the anatomy;
evaluating the location of the first instrument based upon a sensed electrical activity within the anatomy of the at least one electrode substantially circumscribing the at least one lumen; and
slitting the at least one electrode to remove the first instrument from around the second instrument and the anatomy without removing the second instrument;
wherein slitting the at least one electrode includes slitting a polymeric portion that is coupled to a metal portion, wherein the metal portion only partially surrounds the first instrument.
23. The method of claim 22, further comprising:
coupling a first drive patch to the anatomy;
coupling a second drive patch to the anatomy at a location spaced apart from the first drive patch; and
generating voltages in the first drive patch and the second drive patch.
24. The method of claim 23, further comprising:
sensing at least one voltage with the at least one electrode; and
determining, based on the at least one sensed voltage, an impedance of the at least one electrode of the first instrument.
Descripción
CROSS-REFERENCE TO RELATED APPLICATIONS

This application includes subject matter that relates to co-pending U.S. provisional application 61/046,298, filed on Apr. 18, 2008; U.S. patent application Ser. No. 12/117,537, filed on May 8, 2008; U.S. patent application Ser. No. 12/117,549, filed on May 8, 2008; and U.S. patent application Ser. No. 12/421,364 and U.S. patent application Ser. No. 12/421,332, filed concurrently herewith. The entire disclosures of the above applications are incorporated herein by reference.

FIELD

The present disclosure relates generally to surgical navigation systems, and in particular to a system and method for determining a position or location of a sheath within an anatomy.

BACKGROUND

The statements in this section merely provide background information related to the present disclosure and may not constitute prior art.

The human anatomy includes many types of tissue that can either voluntarily or involuntarily, perform certain functions. However, after disease or injury, certain tissues may no longer operate within general anatomical norms. For example, after disease, injury, age, or combinations thereof, the heart muscle may begin to experience certain failures or deficiencies. Some of these failures or deficiencies can be corrected or treated with implantable medical devices (IMDs). These devices can include implantable pulse generator (IPG) devices, pacemakers, implantable cardioverter-defibrillator (ICD) devices, cardiac resynchronization therapy defibrillator devices, or combinations thereof.

One of the main portions of the IMD can include a lead that is directly connected to tissue to be affected by the IMD. The lead can include a tip portion that is directly connected to the anatomical tissue, such as a muscle bundle, and a lead body that connects to the device body or therapeutic driving device. It is generally known that the device body or case portion can be implanted in a selected portion of the anatomical structure, such as in a chest or abdominal wall, and the lead can be inserted through various venous portions so that the tip portion can be positioned at the selected position near or in the muscle group.

The IMDs are implantable devices that may require the use of imaging devices for implantation. The imaging devices can include fluoroscopes that expose a patient and a surgeon to ionizing radiation. In addition, the use of the imaging device can require time for acquiring image data and understanding the images from the image data.

SUMMARY

A position sensing unit (PSU) system is operable to map and illustrate mapped and saved points. The system can determine the location of an electrode by generating a voltage in a patient and calculating an impedance at the electrode. The calculated impedance is used to determine the position of the electrode as in a patient or other appropriate conducting medium.

The saved points may be used to create a map determined with the electrode that can be used to determine a location of a later positioned electrode. The electrode positioned in the anatomy can include a navigation catheter, pacing lead, etc. The map generated with the PSU can be used to guide or navigate a lead to a selected location without external imaging devices. Generally, the navigation catheter or pacing lead can be inserted into the anatomy, via a sheath.

A system for determining a location of an instrument within an anatomy is provided. The system can include a first instrument navigable within the anatomy, which can define at least one lumen. The first instrument can include a proximal end and a distal end. The system can further include a second instrument, which can be received through the at least one lumen and navigable within the anatomy relative to the first instrument. The system can include at least one electrode, which can be coupled to the distal end of the first instrument. The at least one electrode can be responsive to electrical activity to generate at least one signal. The system can include a sensing unit, which can be in contact with the anatomy to sense electrical activity within the anatomy at a location near the instrument. The sensing unit can be in communication with the at least one electrode to receive the at least one signal. The system can further include a control module that can determine, based on the sensed electrical activity and the at least one signal, the location of the first instrument. The at least one electrode can be slittable so that the first instrument can be removed from about the second instrument.

In one example, a system for determining a location of an instrument within an anatomy can be provided. The system can include a first electrode patch in contact with the anatomy. The system can further include a second electrode patch in contact with the anatomy and spaced apart from the first electrode patch. The system can include a first instrument, which can be navigable within the anatomy relative to the first electrode patch and the second electrode patch. The first instrument can define at least one lumen, and can include a distal end. The system can further include a second instrument, which can be received through the at least one lumen. The second instrument can be navigable within the anatomy relative to the first instrument, the first electrode patch and the second electrode patch. The system can include at least one electrode coupled to the distal end of the first instrument. The at least one electrode can be responsive to electrical activity to generate at least one signal. The system can further include a sensing unit, which can be in communication with the first electrode patch and the second electrode patch to generate voltages between the first electrode patch and the second electrode patch. The sensing unit can also be in communication with the at least one electrode of the first instrument to receive the at least one signal. The sensing unit can determine at least one impedance of the at least one electrode of the first instrument based on the at least one signal. The system can also include a control module that can determine, based on the at least one impedance of the at least one electrode of the first instrument, the location of the first instrument within the anatomy.

According to various examples, a method can be provided for determining a location of an instrument within an anatomy. The method can include providing a first instrument that includes at least one lumen. The method can include inserting a second instrument into the at least one lumen. The method can further include inserting the second instrument and at least a portion of the first instrument into the anatomy. The method can also include sensing electrical activity within the anatomy near the portion of the first instrument. The method can include determining, based on the sensed electrical activity, the location of the first instrument. The method can also include slitting the at least one electrode to remove the first instrument from the anatomy without removing the second instrument.

Further areas of applicability will become apparent from the description provided herein. It should be understood that the description and specific examples are intended for purposes of illustration only and are not intended to limit the scope of the present disclosure.

DRAWINGS

The drawings described herein are for illustration purposes only and are not intended to limit the scope of the present disclosure in any way.

FIG. 1 is an environmental view of a mapping or navigation system;

FIG. 2 is a detailed view of a position sensing unit, according to various embodiments;

FIG. 3 is a schematic environmental view of a display device displaying exemplary data generated by the navigation system of FIG. 1;

FIG. 4 is a detail view of an exemplary navigation catheter and exemplary sheath for use with the navigation system of FIG. 1;

FIG. 5 is a detail side view of an exemplary electrode for use with the sheath of FIG. 4;

FIG. 6 is a detail side view of an exemplary electrode for use with the sheath of FIG. 4;

FIG. 7 is a cross-sectional schematic illustration of the electrode of FIG. 6, taken along line 7-7 in FIG. 6;

FIG. 8 is a simplified block diagram illustrating a navigation system for sheath detection;

FIG. 9 is a dataflow diagram that illustrates a control system performed by a control module associated with the navigation system of FIG. 8; and

FIG. 10 is an exemplary flowchart diagram that illustrates one of various control methods performed by the control module of FIG. 9.

DETAILED DESCRIPTION

The following description is merely exemplary in nature and is not intended to limit the present disclosure, application, or uses. It should be understood that throughout the drawings, corresponding reference numerals indicate like or corresponding parts and features. As indicated above, the present teachings are directed towards providing a system and method for determining a location or position of a sheath. It should be noted, however, that the present teachings could be applicable to any appropriate procedure in which it is desirable to determine a position of an instrument within an anatomy. Further, as used herein, the term “module” can refer to an application specific integrated circuit (ASIC), an electronic circuit, a processor (shared, dedicated, or group) and memory that executes one or more software or firmware programs, a combinational logic circuit, and/or other suitable hardware or software, firmware programs or components that provide the described functionality. Therefore, it will be understood that the following discussions are not intended to limit the scope of the appended claims.

As discussed herein, a navigation system, such as the navigation system 20 illustrated in FIG. 1, can be used to navigate a procedure relative to a patient 26. As discussed in detail herein, various instruments can be moved relative to the patient 26 and tracked relative to the patient 26. Although an image-guided system can include acquiring image data of the patient 26, such as with an imaging device 28, such an imaging device is not required, as discussed herein. A portion of the patients' anatomy can be mapped by identifying a plurality of points within the patient by determining a relative location of an instrument. The plurality of points can be illustrated individually, sequentially, or a surface can be illustrated over or without the plurality of points to illustrate or identify a portion of the anatomy of the patient 26. Once the map has been created of the patient or a portion of the patient, either with or without a surface rendered relative to the individual points, a procedure can be guided or navigated using the map or point data. The point or map data 90 can be generated without any additional imaging information, such as image data that can be acquired with a fluoroscopic system, MRI Imaging System, computed tomography (CT) Imaging System, or other imaging systems.

With reference to FIG. 1, the exemplary mapping or navigation system 20 is illustrated. The navigation system 20 can be operated by the user 22 with an instrument 24 to map a selected space, such as a portion of the patient 26. The instrument 24 can also be navigated relative to the patient 26. The instrument 24 can be moved relative to the patient 26 for various procedures, including lead placement relative to the heart, mapping of the heart, mapping of a selected organ of the patient 26, or guiding or navigating the instrument 24 relative to any appropriate portion of the patient 26. Generally, the instrument 24 can comprise any suitable instrument for use with an anatomy, such as a catheter, balloon catheter, mapping catheter, basket catheter, guide wire, arthroscopic system, cardiac lead, orthopedic implant, spinal implant, deep-brain stimulator (DBS) probe, microelectrode recorder probe, macroelectrode stimulation probe, etc.

The navigation system 20 can include various components, such as an optional imaging device 28. The optional imaging device 28 can include a fluoroscope, such as a fluoroscope configured as a C-arm. The C-arm fluoroscope can include an imaging section 30 and an x-ray emitting section 32. The imaging device 28 can be controlled by a controller 34. Images acquired with the imaging device 28 can be displayed on a display 35 that is associated with the imaging device 28, or could be displayed on the display 58. Thus, it will be understood, that a separate display 35 is not required. In addition, if the imaging device 28 is an x-ray imaging device any radio-opaque portions will appear as a part of the image when viewed, including the instrument 24.

The controller 34 can control the imaging device 28 and can store images generated with the imaging device 28 or transmit data or receive instructions via a data transmission or communication line 36 to or from a processor and/or memory, such as one that may be included in a workstation 38. While the optional imaging device 28 illustrated here is a fluoroscopic c-arm other imaging devices, such as CT, MRI, ultrasound, etc., can also be employed. Moreover, it will be understood that the communication line 36 can be any appropriate communication line such as a wired communication line, a wireless communication system, or any other data transfer mechanism.

The navigation system 20 can further include a Position Sensing Unit (PSU) 40, as illustrated in FIG. 2. The PSU 40 can include an impedance or Electrical Potential (EP) system. The PSU 40 can be the LocaLisa® Intracardiac Navigation System, which was commercially available from Medtronic, Inc. of Minneapolis, Minn., USA. The PSU 40 can also be that disclosed in U.S. Pat. Nos. 5,697,377 or 5,983,126 to Wittkampf, incorporated herein by reference. The PSU 40 can include a control or driving unit 42 that includes one or more input or output connectors 44 to interconnect with one or more current conducting electrode or drive patches, which can be generally identified by reference numerals 46, 48 and 50. The electrode or drive patches 46, 48, 50 can be connected directly to the patient 26. As an example, the LocaLisa® device can be used to generate the current in the patient 26. In one example, the drive patches 46, 48, 50 can include three drive patches 46, 48, 50 which can create three substantially orthogonal voltage or current axes x, y, z within the patient 26.

In this regard, for example, a first y-axis drive patch 46 a and a second y-axis drive patch 46 b can be interconnected with the patient 26 to form a y-axis (such as an axis that is generally superior-inferior of a patient) with a conductive path such that the conducted current establishes a voltage potential gradient substantially along this axis and between the drive patches 46 a and 46 b. A related y-axis current flows from the first y-axis drive patch 46 a to the second y-axis drive patch 46 b substantially along the y-axis. Likewise, a first x-axis drive patch 48 a and a second x-axis drive patch 48 b can be connected with the patient 26 to create an x-axis (such as an axis that is generally medial-lateral of a patient) with a voltage gradient substantially along the x-axis between the drive patches 48 a and 48 b and a corresponding x-axis current. Finally, a first z-axis drive patch 50 a and a second z-axis drive patch 50 b can be connected with a patient 26 to create a z-axis (such as an axis that is generally anterior-posterior of a patient) with a voltage potential gradient substantially along the z-axis between the drive patches 50 a and 50 b with a corresponding z-axis current.

The three axes x, y, z are generally formed to have an origin or area of interest that the common intersection or origin of each of the axes x, y, z. Accordingly, the drive patches 46, 48, 50 can be positioned on the patient 26 to achieve the selected placement of the axes x, y, z relative to the patient 26. Each of the drive patches 46 a-50 b can be interconnected with the PSU input/output (I/O) box 42, via a wire connection or other appropriate connection at the connectors 44.

The current applied between the related patches generate a small current, (about 1 microampere to about 100 milliamperes), in the patient along the axis between the respective patch pairs. The induced current can be of a different frequency for each of the related patch pairs to allow for distinguishing which axis x, y, z is being measured. The current induced in the patient 26 will generate a voltage gradient across different portions, such as a heart 80, that can be measured with an electrode, as discussed in further detail herein.

The sensed voltage can be used to identify a position along an axis (whereby each axis can be identified by the particular frequency of the current being measured) to generally determine a position of an electrode along each of the three axes x, y, z. Although a voltage can be sensed, an impedance can also be calculated or measured to determine a location in a similar manner. It will be understood, that a sensing of voltage will not eliminate other possible measurements for position determination, unless specifically indicated. As discussed further herein, the position of the electrode with respect to each of the three axes x, y, z can be used as map data 90 to be illustrated on the display 58. Electrodes within the patient 26 and reference electrode patches 52 are interconnected with the PSU I/O box 42 such that the signals are processed by high impedance circuitry so as to not load and distort the sensed signals.

In addition, one or more electrode or reference patches or reference electrode patches 52 can be interconnected with the patient 26 for reference of guiding or mapping with the instrument 24 relative to the patient 26. The reference electrode patches 52 can include a first reference electrode patch 52 a and a second reference electrode patch 52 b. The placement of the reference electrode patches 52 a, 52 b can be any appropriate position on the patient 26. For example, the first reference electrode patch 52 a can be positioned substantially over the xiphoid process on the skin of the patient 26 directly exterior to the xiphoid process of the patient 26. The second reference electrode patch 52 b can be positioned substantially directly across from the first reference electrode patch 52 a on a dorsal surface of the patient 26. By positioning the reference electrode patch 52 a at this location, the reference electrode patch 52 a has relatively little motion with respect to the heart. The placement of the reference electrode patches 52 a,b at these locations, can enable respiration of the patient 26 to be monitored by measuring the relative voltage or impedance difference between the two reference electrode patches 52 a, 52 b using the PSU 40.

In addition to reference electrode patches 52 a, 52 b being positioned on or near a xiphoid process of a patient, additional various reference patches or reference electrode patches can be positioned at other locations on the patient 26. Greater detail regarding the placement of reference patches or reference electrode patches can be found in U.S. Ser. No. 12/421,332 and U.S. Ser. No. 12/421,364, filed concurrently herewith, and incorporated herein by reference.

With reference to FIG. 1, the PSU I/O box 42 can be interconnected with the workstation 38, via a connection or data transfer system 56. The data transfer system 56 can include a wire transmission, wireless transmission, or any appropriate transmission. The data transfer system 56 can transmit signals 92, which can be analog or digital signals, regarding voltages sensed by the reference electrode patches 52 a, 52 b and signals 199, which can be analog or digital signals, regarding voltages sensed by electrodes on the instrument 24, as will be discussed herein. The workstation 38 can use the signals 92, 199 to determine a relative location of the instrument 24 and to display the determined relative location on the display 58 as instrument position data 201 (FIG. 3).

With continuing reference to FIG. 1, the display 58 can be integral with or separate from the workstation 38. In addition, various interconnected or cooperating processors and/or memory can be provided to process various information, each may be a part of the workstation 38 or separate therefrom. In one example, the workstation 38 can include one or more processors and one or more data storage devices. As can be appreciated, the processors can comprise one or more processing elements capable of implementing a control module 200. At least one of the data storage devices can store one or more instructions contained in a control system associated with the control module 200. In one example, the data storage device can be at least one of random access memory (RAM), read only memory (ROM), a cache, a stack, or the like, which may temporarily or permanently store electronic data. As will be discussed, the control module 200 can receive the signals 92 from the reference electrode patches 52 and the signals 199 from the instrument 24 to determine the position of the instrument 24, and display the determined positions or other data on the display 58.

The navigation system 20 can further include user input or data input devices such as a keyboard 60, a joystick 62, or a foot pedal 64. Each of the input devices, 60-64 can be interconnected with the workstation 38 or appropriate systems for inputting information or data into the workstation 38. This information or data can include identifying appropriate information, as discussed further herein, such as various components, or anatomic regions.

The instrument 24 can include an electrode, as discussed further herein, which is able to sense the voltage generated within the patient 26 due to the drive patches 46 a-50 b positioned on the patient 26. The sensed voltage can be used to calculate an impedance of the tissue in the patient 26 based upon the voltage potential gradient generated between the respective pairs of drive patches 46 a-50 b and the corresponding current. Generally, the current is carried due to an electrolyte in the patient 26, such as blood, interstitial fluid, etc. within a heart 80 and body of the patient 26. The calculated impedance or sensed voltage can be used to determine a location of the electrode of the instrument 24 relative to a selected reference, such as reference electrode patch 52 a or 52 b.

With reference to FIG. 4, according to various embodiments, one or more instruments 24 can be used with the PSU 40, such as a mapping or navigation catheter 100, which can be passed through a deflectable sheath 102. As the navigation catheter 100 can comprise any suitable navigation catheter 100 known in the art, such as a Swan-Ganz Balloon Catheter System sold by Edwards Lifesciences, the navigation catheter 100 will not be discussed in great detail herein. Briefly, however, the navigation catheter 100 can include various portions, such as an expandable, inflatable or balloon portion 106, a catheter 108 that can define a lumen 110 and one or more electrodes 112.

The balloon portion 106 can be formed at a distal end 114 of the catheter 108. The balloon portion 106, when inflated, can act as a stop when the navigation catheter 100 is being moved through the heart 80 or other anatomical portion. The balloon portion 106 can be inflated or deflated as selected by the user 22. For example, the inflation of the balloon portion 106 can be performed in any appropriate manner such as directing a fluid, such as a liquid or gas, through the lumen 110.

The electrodes 112 can include a first or tip electrode 112 a and a second or ring electrode 112 b. The tip electrode 112 a can be coupled to a distal end 106 a of the catheter 108, while the ring electrode 112 b can be provided on a proximal end 108 a of the balloon portion 106. The electrodes 112 can be used to sense voltages within the patient 26 when the navigation catheter 100 is positioned within the patient 26 and the drive patches 46-50 are active or being driven. In this regard, with reference to FIG. 1, the electrodes 112 can sense voltages produced within the patient 26 by the drive patches 46-50, which can be transmitted to the PSU 40 as a signal 89. Various conductors can be used to transfer the sensed voltages from the electrodes 112 to the PSU I/O box 42. From the sensed voltages, the PSU 40 can calculate impedances to determine a position of the navigation catheter 100 within the anatomy. With reference to FIG. 3, the position of the navigation catheter 100 can be displayed as an icon 100 i on the display 58. Note that the icon 100 i can be superimposed on the map data 90 illustrated on the display 58. The navigation catheter 100 can be moved relative to the patient 26 in any appropriate manner, such as with the sheath 102.

With further reference to FIG. 4, the sheath 102 can define a throughbore or lumen 120, which can receive the navigation catheter 100. The sheath 102 can be used by the user 22 to direct or guide the navigation catheter 100 within the anatomy, and can also be used to direct or guide a lead for use with an IMD within the anatomy. The sheath 102 can be composed of a suitable deflectable material, such as a biocompatible polymer, and can include a proximal end 122, a steering mechanism 124 and a distal end 126. The proximal end 122 of the sheath 102 can generally extend outside of the anatomy, and can be configured to enable the user 22 to manipulate and direct the sheath 102 within the anatomy.

The steering mechanism 124, in one example, can comprise a pull wire 124 a, which can be coupled to an interior surface 120 a of the lumen 120 near the distal end 126. In one example, the pull wire 124 a could be coupled to an electrode 130 and could serve as a conductor for the electrode 130. As is generally known, the pull wire 124 a can be manipulated or pulled by the user to curve or bend the distal end 126 of the sheath 102. This can enable the distal end 126 of the sheath 102 to navigate the curvatures within the anatomy and to direct the exit of an instrument from the lumen 120.

With reference to FIG. 4, the distal end 126 of the sheath 102 can include one or more electrodes 130. In one example, the sheath 102 can include two electrodes 130, and in one example, the sheath 102 can include four electrodes 130. The use of at least two electrodes 130 can enable the PSU 40 to determine a position of the distal end 126 of the sheath 102 based on voltages sensed by the electrodes 130. In this regard, the electrodes 130 can be used to sense voltages within the patient 26 when the sheath 102 is positioned within the patient 26 and the drive patches 46-50 are active or being driven. The electrodes 130 can sense voltages produced within the patient 26 by the drive patches 46-50, and from the sensed voltages impedances can be calculated by the PSU 40 to determine a position of the sheath 102. Various conductors can be used to transfer the sensed voltages from the electrodes 130 to the PSU I/O box 42. With reference to FIG. 3, the position of the distal end 126 of the sheath 102 can be displayed on the display 58 as an icon 102 i. Note that the icon 102 i can be superimposed on the map data 90 illustrated on the display 58.

The sheath 102 can be used to insert various instruments into the anatomy, and in one example, can be used to guide a lead into the anatomy. Due to the size of a connector on the proximal end of the lead, it can be desirable to cut or slit the sheath 102 after the lead has been properly positioned in the anatomy. In order to slit the sheath 102, the electrodes 130 can be slittable.

In one example, with reference to FIG. 5, at least one of the electrodes 130 can comprise an electrode 130 a, which can comprise a metal portion, such as a metal electrode 132, which can be coupled to a conductive polymer band 134. The metal electrode 132 can have any desired shape, but can generally be shaped and sized such that the metal electrode 132 does not extend completely around or about the circumference of the sheath 102. For example, the metal electrode 132 can comprise a triangular shape, which can be positioned to guide a cutting tool to the side of the metal electrode 132, but the metal electrode 132 could comprise any suitable shape, such as a trapezoid, rectangle, square, oval, diamond, etc. The metal electrode 132 can be coupled to the PSU 40 via a suitable connector 132 a. It should be noted that the connector 132 a can also comprise the pull wire 124 a, if desired. The metal band 136 can be coupled to and in communication with the conductive polymer band 134.

The conductive polymer band 134 can be coupled to the metal electrode 132 such that the electrode 130 can circumscribe the sheath 102. Thus, the size of the metal electrode 132 can influence the size of the polymer band 134. In one example, the metal electrode 132 can be embedded in the polymer band 134, however, it should be understood that the metal electrode 132 can be coupled adjacent to and not embedded within the polymer band 134. The polymer band 134 can be composed of any suitable conductive polymeric material, such as a silicon-based conductive polymeric material, and can cooperate with the metal electrode 132 to sense a voltage within the patient 26 uniformly about the circumference of the sheath 102.

In one of various examples, with reference to FIGS. 6 and 7, at least one of the electrodes 130 on the sheath 102 can comprise an electrode 130 b, which can include a metal portion, such as a metal band 136 and a conductive polymer band 138. It should be noted that the electrodes 130 on the sheath 102 can comprise any desired combinations of the electrodes 130 a and 130 b. The metal band 136 can in one example comprise a gold (Au) metal band, however, the metal band 136 can comprise any conductive metal or metal alloy that can be easily slit with a cutting device. The metal band 136, in one example, can be positioned within the sheath 102, such that the metal band 136 is adjacent to an interior surface 139 of the sheath 102. The metal band 136 can be coupled to the PSU 40 via a suitable connector 136 a. It should be noted that the connector 136 a can also comprise the pull wire 124 a, if desired. The metal band 136 can also be coupled to and in communication with the conductive polymer band 138 via a bore 140 defined through the sheath 102.

In this regard, with reference to FIG. 7, the conductive polymer band 138 can be formed about the circumference of the sheath 102, and generally, can be formed about an exterior surface 142 of the sheath 102 at about the same location as the metal band 136, such that the metal band 136 and conductive polymer band 138 are concentric about the sheath 102. The conductive polymer band 138 can be formed over the bore 140, so that during the forming of the conductive polymer band 138, at least a portion 138 a of the conductive polymer can flow through the bore 140 to contact the metal band 136. The portion 138 a of the conductive polymer within the bore 140 can enable electrical communication between the metal band 136 and the conductive polymer band 138. The conductive polymer band 138 can comprise any suitable conductive polymeric material, such as a silicon-based conductive polymeric material, however any suitable conductive polymeric material could be employed.

With reference to FIG. 4, the electrodes 130 can sense voltages produced within the patient 26 by the drive patches 46-50, which can be output as a signal 199, and from the sensed voltages impedances can be calculated by the PSU 40 to determine a position of the sheath 102. With reference to FIG. 8, a simplified block diagram schematically illustrates an exemplary navigation system 20 for implementing the control module 200. The navigation system 20 can include the instrument 24, which in one example can comprise the navigation catheter 100 having the electrodes 112, and the sheath 102 having the electrodes 130. The navigation system 20 can also comprise the drive patches 46, 48, 50, the reference electrodes 52, the PSU 40, which can include the PSU I/O box 42, the display 58 and the workstation 38, which can implement the control module 200.

In one example, the PSU 40, via the PSU I/O box 42, can transmit a voltage 98 to the drive patches 46, which can create voltages in the patient 26. The electrodes 130 of the sheath 102 can transmit a signal 199 to the PSU I/O box 42, which can comprise the voltages sensed by the electrodes 130. Based on the voltages sensed by the electrodes 130, the control module 200 can determine a position of the sheath 102 within the anatomy. The electrodes 112 of the navigation catheter 100 can sense the voltages within the patient 26, and can transmit this data as the signal 89 to the PSU I/O box 42. Based on the sensed voltages, the PSU 40 can determine a position or location of the navigation catheter 100 within the anatomy.

The reference electrodes 52 can sense the voltages generated by the drive patches 46, 48, 50, and can transmit these sensed voltages as a signal 101 to the PSU I/O box 42. The signals 89, 199, 101 received by the PSU I/O box 42 can be transmitted to the workstation 38 as the signal 56, which can be received as input by the control module 200. Based on the data in the signal 56, the control module 200 can determine the position of the sheath 102 relative to the navigation catheter 100, and can output this data as instrument position data 201 for the display 58. The instrument position data 201 can comprise the icons 100 i, 102 i, which can indicate the position of the navigation catheter 100 and sheath 102 within the anatomy. The control module 200 can also output the map data 90 to the display 58. The instrument position data 201 can be superimposed on the map data 90, if desired.

In this regard, with reference to FIG. 9, a dataflow diagram illustrates the control system that can be embedded within the control module 200. Various embodiments of the control system according to the present disclosure can include any number of sub-modules embedded within the control module 200. The sub-modules shown may be combined and/or further partitioned to similarly determine a position of the navigation catheter 100 and the sheath 102. In various embodiments, the control module 200 can include a PSU control module 202 and a navigation control module 204.

The PSU control module 202 can receive as input sheath data 206, navigation catheter data 208 and reference data 210. The sheath data 206 can comprise the voltages sensed by the electrodes 130 of the sheath 102 or the data provided by signal 199. The navigation catheter data 208 can comprise the voltages sensed by the electrodes 112 of the navigation catheter 100, which can comprise the data from the signal 89. The reference data 210 can comprise the voltages sensed by the reference electrode patches 52 a, 52 b, which can comprise the data from the signal 101. The PSU control module 202 can also receive start-up data 212 as input. The start-up data 212 can comprise a signal to activate the PSU 40.

Based on the start-up data 212, the PSU 40 can output drive data 214. The drive data 214 can comprise a signal, which can drive the drive patches 46, 48, 50. Based on the sheath data 206, the navigation catheter data 208 and the reference data 210, the PSU control module 202 can set position data 216 for the navigation control module 204. The position data 216 can comprise data indicative of the position of the sheath 102 within the anatomy, and the position of the navigation catheter 100 relative to the reference electrodes 52. The position of the sheath 102 can be determined based on the impedances of the electrodes 130 of the sheath 102, which can be determined from the voltages sensed by the electrodes 130 of the sheath 102.

The navigation control module 204 can receive as input the position data 216. Based on the position data 216, the navigation control module 204 can output the map data 90, and instrument position data 201. The instrument position data 201 can comprise the icon 100 i, which can graphically represent the position of the navigation catheter 100 and/or the icon 102 i, which can graphically represent the position of the sheath 102. The navigation control module 204 can also set the start-up data 212 for the PSU control module 202, based upon receipt of an input, such as a user input from one of the user input devices 60-64.

With reference now to FIG. 10, a flowchart diagram illustrates an exemplary method performed by the control module 200. At block 300, the method can determine if start-up data 212 has been received. If start-up data 212 has been received, then the method can go to block 302. Otherwise, the method can loop.

At block 302, the method can output the drive data 214 to drive the drive patches 46, 48, 50. At block 304, the method can determine impedances of the reference electrodes 52, based on the reference data 210. At block 306, the method can determine impedances of the electrodes 130 of the sheath 102, based on the sheath data 206. At block 308, the method can determine impedances of the electrodes 112 of the navigation catheter 100, based on the navigation catheter data 208. At block 310, the method can determine a position of the navigation catheter 100, given the impedances of the electrodes 112 of the navigation catheter 100 and the impedances of the reference electrodes 52.

At block 312, the method can determine a position of the sheath 102, given the impedances of the electrodes 130 of the sheath 102 and the impedances of the reference electrodes 52. At block 314, the method can output the map data 90 and the instrument position data 201 to the display 58. At block 318, the method can determine if a shut-down request was received. If a shut-down request was not received, then the method can go to block 302.

Thus, the navigation system 20 can provide a passive means for determining a location or position of the sheath 102 within the anatomy. In this regard, by sensing the impedances of the electrodes 130 of the sheath 102, the navigation system 20 can determine the position of the sheath 102 within the anatomy. This can enable the user 22 to know where the sheath 102 relative to other instruments in the anatomy, such as the navigation catheter 100. This can provide the user 22 with better situational awareness of the position of the sheath 102 relative to the navigation catheter 100, which can enable the user 22 to more effectively manipulate the navigation catheter 100 via the sheath 102. In addition, knowing the position of the sheath 102 within the anatomy may enable the user 22 to perform a mapping procedure faster.

While specific examples have been described in the specification and illustrated in the drawings, it will be understood by those of ordinary skill in the art that various changes may be made and equivalents may be substituted for elements thereof without departing from the scope of the present disclosure. Furthermore, the mixing and matching of features, elements and/or functions between various examples is expressly contemplated herein so that one of ordinary skill in the art would appreciate from this disclosure that features, elements and/or functions of one example may be incorporated into another example as appropriate, unless described otherwise, above. Moreover, many modifications may be made to adapt a particular situation or material to the teachings of the present disclosure without departing from the essential scope thereof. Therefore, it is intended that the present disclosure not be limited to the particular examples illustrated by the drawings and described in the specification as the best mode presently contemplated for carrying out this disclosure, but that the scope of the present disclosure will include any embodiments falling within the foregoing description.

For example, while the position of the sheath 102 has been described as being determined based on a sensed voltage of the electrodes 130, the sheath 102 may be constructed somewhat differently. In this regard, at least one tracking device, such as an electromagnetic coil, could be coupled at or near the distal end 126 of the sheath 102. Then, a suitable navigation system could be used to determine a position of the sheath 102, such as the StealthStation® AXIEM™ Electromagnetic Tracking System, commercially available from Medtronic, Inc. of Minneapolis, Minn., USA, or the navigation system described in commonly assigned U.S. Ser. No. 12/115,907, filed on May 6, 2008, which is incorporated herein by reference.

Citas de patentes
Patente citada Fecha de presentación Fecha de publicación Solicitante Título
US366115716 Abr 19709 May 1972Nat Res DevInhibited demand pacer with a two-rate pulse generator
US383734720 Abr 197224 Sep 1974Electro Catheter CorpInflatable balloon-type pacing probe
US399562311 Feb 19767 Dic 1976American Hospital Supply CorporationMultipurpose flow-directed catheter
US450668017 Mar 198326 Mar 1985Medtronic, Inc.Drug dispensing body implantable lead
US461924620 May 198528 Oct 1986William Cook, Europe A/SCollapsible filter basket
US46499248 Jul 198517 Mar 1987Consiglio Nazionale Delle RicercheMethod for the detection of intracardiac electrical potential fields
US469630423 Abr 198629 Sep 1987Thomas J. FogartyThermodilution flow-directed catheter assembly and method
US48012971 Jun 198431 Ene 1989Edward Weck IncorporatedCatheter having slit tip
US4852580 *6 Nov 19871 Ago 1989Axiom Medical, Inc.Catheter for measuring bioimpedance
US503524630 Jun 198830 Jul 1991Heuvelmans Joannes H AMethod for carrying out hemodynamic measurements on a patient and flow-directed balloon catheter used for this
US507628530 Mar 199031 Dic 1991Medtronic, Inc.Screw-in lead
US50787142 Mar 19907 Ene 1992Jefferson KatimsMethod and apparatus for placement of a probe in the body and the medical procedure for guiding and locating a catheter or probe in the body
US509984523 May 199031 Mar 1992Micronix Pty Ltd.Medical instrument location means
US514641418 Abr 19908 Sep 1992Interflo Medical, Inc.Method and apparatus for continuously measuring volumetric flow
US516723930 May 19911 Dic 1992Endomedix CorporationAnchorable guidewire
US52556803 Sep 199126 Oct 1993General Electric CompanyAutomatic gantry positioning for imaging systems
US526562225 Oct 199030 Nov 1993C. R. Bard, Inc.Guidewire having radially expandable member and method for guiding and advancing a catheter using the same
US529754923 Sep 199229 Mar 1994Endocardial Therapeutics, Inc.Endocardial mapping system
US534229524 Sep 199330 Ago 1994Cardiac Pathways CorporationCatheter assembly, catheter and multi-port introducer for use therewith
US538514830 Jul 199331 Ene 1995The Regents Of The University Of CaliforniaCardiac imaging and ablation catheter
US539119920 Jul 199321 Feb 1995Biosense, Inc.Apparatus and method for treating cardiac arrhythmias
US540331129 Mar 19934 Abr 1995Boston Scientific CorporationElectro-coagulation and ablation and other electrotherapeutic treatments of body tissue
US544348923 Sep 199422 Ago 1995Biosense, Inc.Apparatus and method for ablation
US548042223 Sep 19942 Ene 1996Biosense, Inc.Apparatus for treating cardiac arrhythmias
US551292017 Ago 199430 Abr 1996Mitsubishi Electric Research Laboratories, Inc.Locator device for control of graphical objects
US552287428 Jul 19944 Jun 1996Gates; James T.Medical lead having segmented electrode
US553800730 Ene 199523 Jul 1996Gorman; Peter G.Biomedical response monitor and method using identification signal
US554695123 Sep 199420 Ago 1996Biosense, Inc.Method and apparatus for studying cardiac arrhythmias
US55580916 Oct 199324 Sep 1996Biosense, Inc.Magnetic determination of position and orientation
US556880912 Jul 199529 Oct 1996Biosense, Inc.Apparatus and method for intrabody mapping
US559293914 Jun 199514 Ene 1997Martinelli; Michael A.Method and system for navigating a catheter probe
US559884831 Mar 19944 Feb 1997Ep Technologies, Inc.Systems and methods for positioning multiple electrode structures in electrical contact with the myocardium
US560108426 May 199511 Feb 1997University Of WashingtonDetermining cardiac wall thickness and motion by imaging and three-dimensional modeling
US563927623 Sep 199417 Jun 1997Rapid Development Systems, Inc.Device for use in right ventricular placement and method for using same
US569737722 Nov 199516 Dic 1997Medtronic, Inc.Catheter mapping system and method
US571394628 Oct 19963 Feb 1998Biosense, Inc.Apparatus and method for intrabody mapping
US57978497 Mar 199725 Ago 1998Sonometrics CorporationMethod for carrying out a medical procedure using a three-dimensional tracking and imaging system
US580040721 Dic 19951 Sep 1998Eldor; JosephMultiple hole epidural catheter
US584002521 Nov 199724 Nov 1998Biosense, Inc.Apparatus and method for treating cardiac arrhythmias
US591619330 Nov 199629 Jun 1999Heartport, Inc.Endovascular cardiac venting catheter and method
US594402228 Abr 199731 Ago 1999American Cardiac Ablation Co. Inc.Catheter positioning system
US59831261 Ago 19979 Nov 1999Medtronic, Inc.Catheter location system and method
US60093491 Oct 199728 Dic 1999Pacesetter, Inc.System and method for deriving hemodynamic signals from a cardiac wall motion sensor
US601644727 Oct 199818 Ene 2000Medtronic, Inc.Pacemaker implant recognition
US60502674 Feb 199818 Abr 2000American Cardiac Ablation Co. Inc.Catheter positioning system
US608852715 Oct 199611 Jul 2000Zbig Vision Gesellschaft Fur Neue Bildgestaltung MbhApparatus and process for producing an image sequence
US609010517 Nov 199718 Jul 2000Rita Medical Systems, Inc.Multiple electrode ablation apparatus and method
US61225523 Mar 199919 Sep 2000Cardiac Pacemakers, Inc.Insertion apparatus for left ventricular access lead
US61529465 Mar 199828 Nov 2000Scimed Life Systems, Inc.Distal protection device and method
US619623010 Sep 19986 Mar 2001Percardia, Inc.Stent delivery system and method of use
US622654716 Nov 19981 May 2001Roke Manor Research LimitedCatheter tracking system
US62368865 Dic 199722 May 2001Technology Commercialization InternationalMethod for producing a tomographic image of the body and electric impedance tomograph
US624030723 Sep 199329 May 2001Endocardial Solutions, Inc.Endocardial mapping system
US624646823 Oct 199812 Jun 2001Cyra TechnologiesIntegrated system for quickly and accurately imaging and modeling three-dimensional objects
US625612131 Mar 20003 Jul 2001Nanovia, LpApparatus for ablating high-density array of vias or indentation in surface of object
US630149816 Abr 19999 Oct 2001Cornell Research Foundation, Inc.Method of determining carotid artery stenosis using X-ray imagery
US633035629 Sep 199911 Dic 2001Rockwell Science Center LlcDynamic visual registration of a 3-D object with a graphical model
US638918717 Jun 199814 May 2002Qinetiq LimitedOptical fiber bend sensor
US647020513 Mar 200122 Oct 2002Siemens AktiengesellschaftMedical instrument for insertion into an examination subject, and medical examination/treatment device employing same
US64904741 Ago 19973 Dic 2002Cardiac Pathways CorporationSystem and method for electrode localization using ultrasound
US65277826 Jun 20014 Mar 2003Sterotaxis, Inc.Guide for medical devices
US65462707 Jul 20008 Abr 2003Biosense, Inc.Multi-electrode catheter, system and method
US656915924 Feb 200027 May 2003Rita Medical Systems, Inc.Cell necrosis apparatus
US65691607 Jul 200027 May 2003Biosense, Inc.System and method for detecting electrode-tissue contact
US65744984 Nov 19993 Jun 2003Super Dimension Ltd.Linking of an intra-body tracking system to external reference coordinates
US659598911 May 200022 Jul 2003Atrionix, Inc.Balloon anchor wire
US660227112 Dic 20005 Ago 2003Medtronic Ave, Inc.Collapsible blood filter with optimal braid geometry
US661114122 Dic 199926 Ago 2003Howmedica Leibinger IncHybrid 3-D probe tracked by multiple sensors
US661170517 Jul 200126 Ago 2003Motorola, Inc.Wireless electrocardiograph system and method
US670117629 Oct 19992 Mar 2004Johns Hopkins University School Of MedicineMagnetic-resonance-guided imaging, electrophysiology, and ablation
US671480614 Sep 200130 Mar 2004Medtronic, Inc.System and method for determining tissue contact of an implantable medical device within a body
US677199624 May 20013 Ago 2004Cardiac Pacemakers, Inc.Ablation and high-resolution mapping catheter system for pulmonary vein foci elimination
US686819519 Feb 200415 Mar 2005Fuji Photo Optical Co., Ltd.Device for detecting three-dimensional shapes of elongated flexible body
US688862326 Feb 20033 May 2005Dynamic Technology, Inc.Fiber optic sensor for precision 3-D position measurement
US689209118 Feb 200010 May 2005Biosense, Inc.Catheter, method and apparatus for generating an electrical map of a chamber of the heart
US689830222 May 200024 May 2005Emory UniversitySystems, methods and computer program products for the display and visually driven definition of tomographic image planes in three-dimensional space
US699037012 Abr 200024 Ene 2006Endocardial Solutions, Inc.Method for mapping heart electrophysiology
US70205226 Sep 200028 Mar 2006St. Jude Medical AbDual chamber heart stimulator with evoked response detector
US704707315 Nov 200116 May 2006St. Jude Medical AbCardiac stimulating device
US708904530 Ago 20028 Ago 2006Biosense Webster, Inc.Catheter and method for mapping Purkinje fibers
US718920812 Abr 200013 Mar 2007Endocardial Solutions, Inc.Method for measuring heart electrophysiology
US720798927 Oct 200324 Abr 2007Biosense Webster, Inc.Method for ablating with needle electrode
US721543022 Nov 20048 May 2007Leica Geosystems Hds LlcIntegrated system for quickly and accurately imaging and modeling three-dimensional objects
US72633976 Abr 200428 Ago 2007St. Jude Medical, Atrial Fibrillation Division, Inc.Method and apparatus for catheter navigation and location and mapping in the heart
US73051219 Mar 20074 Dic 2007Orametrix, Inc.Method for creating single 3D surface model from a point cloud
US732807112 Oct 20055 Feb 2008Pacesetter, Inc.Lead placement device
US736990110 Feb 20056 May 2008Pacesetter, Inc.Myocardial lead and lead system
US742130031 Oct 20052 Sep 2008Medtronic, Inc.Implantation of medical device with measurement of body surface potential
US747914118 Nov 200420 Ene 2009Siemens AktiengesellschaftAblation tip catheter device with integrated imaging, ECG and positioning devices
US752958419 Feb 20045 May 2009Medtronic, Inc.Pacing method
US768675713 Sep 200530 Mar 2010Olympus CorporationPosition detecting apparatus, body-insertable apparatus system, and position detecting method
US771560412 Ene 200611 May 2010Siemens Medical Solutions Usa, Inc.System and method for automatically registering three dimensional cardiac images with electro-anatomical cardiac mapping data
US782432818 Sep 20062 Nov 2010Stryker CorporationMethod and apparatus for tracking a surgical instrument during surgery
US78487878 Jul 20057 Dic 2010Biosense Webster, Inc.Relative impedance measurement
US794121331 Jul 200810 May 2011Medtronic, Inc.System and method to evaluate electrode position and spacing
US798863929 Dic 20062 Ago 2011St. Jude Medical, Atrial Fibrillation Division, Inc.System and method for complex geometry modeling of anatomy using multiple surface models
US810690515 Abr 200931 Ene 2012Medtronic, Inc.Illustrating a three-dimensional nature of a data set on a two-dimensional display
US813546726 Jun 200913 Mar 2012Medtronic, Inc.Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
US8155756 *25 Feb 200910 Abr 2012Pacesetter, Inc.Motion-based optimization for placement of cardiac stimulation electrodes
US817568116 Dic 20088 May 2012Medtronic Navigation Inc.Combination of electromagnetic and electropotential localization
US818519215 Abr 200922 May 2012Regents Of The University Of MinnesotaCorrecting for distortion in a tracking system
US820899113 Abr 200926 Jun 2012Medtronic, Inc.Determining a material flow characteristic in a structure
US821401813 Abr 20093 Jul 2012Medtronic, Inc.Determining a flow characteristic of a material in a structure
US822445624 Nov 200417 Jul 2012Advanced Neuromodulation Systems, Inc.Directional stimulation lead and orientation system
US823900111 Jul 20057 Ago 2012Medtronic Navigation, Inc.Method and apparatus for surgical navigation
US82603958 May 20084 Sep 2012Medtronic, Inc.Method and apparatus for mapping a structure
US834075113 Abr 200925 Dic 2012Medtronic, Inc.Method and apparatus for determining tracking a virtual point defined relative to a tracked member
US834506715 Abr 20091 Ene 2013Regents Of The University Of MinnesotaVolumetrically illustrating a structure
US835577430 Oct 200915 Ene 2013Medtronic, Inc.System and method to evaluate electrode position and spacing
US836425215 Abr 200929 Ene 2013Medtronic, Inc.Identifying a structure for cannulation
US839196515 Abr 20095 Mar 2013Regents Of The University Of MinnesotaDetermining the position of an electrode relative to an insulative cover
US840161623 Sep 201119 Mar 2013Medtronic Navigation, Inc.Navigation system for cardiac therapies
US842179926 Ene 201216 Abr 2013Regents Of The University Of MinnesotaIllustrating a three-dimensional nature of a data set on a two-dimensional display
US842453615 Abr 200923 Abr 2013Regents Of The University Of MinnesotaLocating a member in a structure
US844262515 Abr 200914 May 2013Regents Of The University Of MinnesotaDetermining and illustrating tracking system members
US84573718 May 20084 Jun 2013Regents Of The University Of MinnesotaMethod and apparatus for mapping a structure
US84946089 Abr 200923 Jul 2013Medtronic, Inc.Method and apparatus for mapping a structure
US849461427 Jul 201023 Jul 2013Regents Of The University Of MinnesotaCombination localization system
US85327349 Abr 200910 Sep 2013Regents Of The University Of MinnesotaMethod and apparatus for mapping a structure
US20010000800 *21 Dic 20003 May 2001Cardiac Pacemakers, Inc.System and assembly having conductive fixation features
US200100319205 Feb 200118 Oct 2001The Research Foundation Of State University Of New YorkSystem and method for performing a three-dimensional virtual examination of objects, such as internal organs
US2002003809420 Nov 200128 Mar 2002Peter GormanHeart rate monitor and method using detection to eliminate errors from interference
US2002004581014 Feb 200118 Abr 2002Shlomo Ben-HaimMethod for mapping a heart using catheters having ultrasonic position sensors
US200200493757 Sep 200125 Abr 2002Mediguide Ltd.Method and apparatus for real time quantitative three-dimensional image reconstruction of a moving organ and intra-body navigation
US2002007754420 Sep 200120 Jun 2002Ramin ShahidiEndoscopic targeting method and system
US200201116628 Feb 200215 Ago 2002Iaizzo Paul A.System and method for placing an implantable medical device within a body
US200201474885 Abr 200110 Oct 2002Doan Phong D.Body implantable lead with improved tip electrode assembly
US200201838175 Dic 20015 Dic 2002Paul Van VenrooijDirectional brain stimulation and recording leads
US2003002811810 Oct 20026 Feb 2003Boston Scientific CorporationInteractive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions
US2003005532417 Oct 200120 Mar 2003Imagyn Medical Technologies, Inc.Signal processing method and device for signal-to-noise improvement
US2003007849424 Oct 200124 Abr 2003Scimed Life Systems, Inc.Systems and methods for guiding and locating functional elements on medical devices positioned in a body
US200301008213 Ene 200329 May 2003Therasense, Inc.Analyte monitoring device and methods of use
US2003010885316 May 200112 Jun 2003Edna ChosackEndoscopic tutorial system for the pancreatic system
US2003011490818 Dic 200219 Jun 2003Erhard FlachEpicardial electrode lead, introducer for such a lead and set of instruments for electrode implantaion
US2003022543430 May 20024 Dic 2003Jerald GlantzMicrocatheter
US2003023178913 Dic 200218 Dic 2003Scimed Life Systems, Inc.Computer generated representation of the imaging pattern of an imaging device
US2004000107528 Jun 20021 Ene 2004Silicon Graphics, Inc.System for physical rotation of volumetric display enclosures to facilitate viewing
US200400193187 Nov 200229 Ene 2004Wilson Richard R.Ultrasound assembly for use with a catheter
US20040019359 *24 Jul 200229 Ene 2004Worley Seth J.Telescopic introducer with a compound curvature for inducing alignment and method of using the same
US2004004429519 Ago 20024 Mar 2004Orthosoft Inc.Graphical user interface for computer-assisted surgery
US2004006415915 Nov 20011 Abr 2004Hoijer Carl JohanCardiac stimulating device
US2004006831225 Abr 20038 Abr 2004Medtronic, Inc.Delivery of active fixation implatable lead systems
US2004007058211 Oct 200215 Abr 2004Matthew Warren Smith To Sonocine, Inc.3D modeling system
US2004009780514 Jul 200320 May 2004Laurent VerardNavigation system for cardiac therapies
US20040097806 *19 Nov 200220 May 2004Mark HunterNavigation system for cardiac therapies
US2004016259913 Feb 200319 Ago 2004Kurth Paul A.Temporarily secured guidewire and catheter for use in the coronary venous system and method of using the same
US200401990823 Abr 20037 Oct 2004Ostroff Alan H.Selctable notch filter circuits
US2004021529823 Abr 200328 Oct 2004Mark RichardsonStabilizing guide wire apparatus for use with implantable device
US2004022845313 May 200418 Nov 2004Dobbs Andrew BrunoMethod and system for simulating X-ray images
US2004023639524 Jun 200425 Nov 2004Medtronic, Inc.System and method for placing an implantable medical device within a body
US2004024928119 May 20049 Dic 2004Bjorn OlstadMethod and apparatus for extracting wall function information relative to ultrasound-located landmarks
US200402494303 Jun 20039 Dic 2004Medtronic, Inc.Implantable medical electrical lead
US200402544376 Abr 200416 Dic 2004Hauck John A.Method and apparatus for catheter navigation and location and mapping in the heart
US2005000447628 May 20046 Ene 2005Saeed PayvarMethod and apparatus for detecting ischemia
US2005001888812 Dic 200227 Ene 2005Zonneveld Frans WesselMethod, system and computer program of visualizing the surface texture of the wall of an internal hollow organ of a subject based on a volumetric scan thereof
US200501195503 Nov 20042 Jun 2005Bracco Imaging, S.P.A.System and methods for screening a luminal organ ("lumen viewer")
US2005017715123 Jul 200311 Ago 2005Coen Thomas P.Irrigation sheath
US200501874321 Feb 200525 Ago 2005Eric Lawrence HaleGlobal endoscopic viewing indicator
US2005024580314 Mar 20033 Nov 2005Glenn Jr William VSystem and method for analyzing and displaying computed tomography data
US2005028858628 Jun 200429 Dic 2005Bozidar Ferek-PetricElectrode location mapping system and method
US2006001352313 Jul 200519 Ene 2006Luna Innovations IncorporatedFiber optic position and shape sensing device and method relating thereto
US2006005860425 Ago 200416 Mar 2006General Electric CompanySystem and method for hybrid tracking in surgical navigation
US200601165761 Dic 20041 Jun 2006Scimed Life Systems, Inc.System and use thereof to provide indication of proximity between catheter and location of interest in 3-D space
US2006011777323 Ene 20068 Jun 2006Hussmann CorporationRefrigeration system and method of operating the same
US2006013588322 Dic 200522 Jun 2006Jonsson HelgiSystems and methods for processing limb motion
US2006015346826 Ago 200313 Jul 2006Torsten SolfImaging system and method for optimizing an x-ray image
US2006017326828 Ene 20053 Ago 2006General Electric CompanyMethods and systems for controlling acquisition of images
US2006017338124 Nov 20033 Ago 2006Kai EckCatheter
US2006020004928 Sep 20057 Sep 2006Giovanni LeoMedical apparatus system having optical fiber load sensing capability
US2006020615719 Ago 200314 Sep 2006Carl-Johan HoijerHeart stimulator detecting atrial arrhythmia by determing wall distension by impedance measuring
US200602295135 Abr 200612 Oct 2006Kabushiki Kaisha ToshibaDiagnostic imaging system and image processing system
US200602295949 Dic 200512 Oct 2006Medtronic, Inc.Method for guiding a medical device
US2006024752028 Abr 20052 Nov 2006Boston Scientific Scimed, Inc.Automated manipulation of imaging device field of view based on tracked medical device position
US200602531165 May 20069 Nov 2006Boaz AvitallPreshaped localization catheter, system, and method for graphically reconstructing pulmonary vein ostia
US2007001608430 Ago 200418 Ene 2007Andre DenaultCatherter for measuring an intraventricular pressure and method of using same
US200700380528 Ago 200615 Feb 2007Enpath Medical, Inc.Fiber optic assisted medical lead
US2007004341316 Ago 200622 Feb 2007Eversull Christian SApparatus and methods for delivering transvenous leads
US2007004666131 Ago 20051 Mar 2007Siemens Medical Solutions Usa, Inc.Three or four-dimensional medical imaging navigation methods and systems
US2007004981730 Ago 20051 Mar 2007Assaf PreissSegmentation and registration of multimodal images using physiological data
US2007006083315 Sep 200515 Mar 2007Hauck John AMethod of scaling navigation signals to account for impedance drift in tissue
US2007006688921 Sep 200622 Mar 2007Siemens AktiengesellschaftMethod for localizing a medical instrument introduced into the body of an examination object
US200701123889 Ene 200717 May 2007Cardiac Pacemakers, Inc.Cardiac pacing using sensed coronary vein blood temperature and left ventricular flow rate
US2007012394431 Oct 200631 May 2007Mark ZdeblickElectrical angle gauge
US2007013572122 Nov 200614 Jun 2007Mark ZdeblickExternal continuous field tomography
US2007013580314 Sep 200614 Jun 2007Amir BelsonMethods and apparatus for performing transluminal and other procedures
US2007015601920 Jul 20065 Jul 2007Larkin David QRobotic surgery system including position sensors using fiber bragg gratings
US20070156132 *30 Dic 20055 Jul 2007Darrell DrysenInjection molded irrigated tip electrode and catheter having the same
US2007016490030 Dic 200519 Jul 2007Schneider Mark DTherapy delivery system including a navigation element
US200701678012 Dic 200519 Jul 2007Webler William EMethods and apparatuses for image guided medical procedures
US2007023289830 Mar 20074 Oct 2007Medtronic Vascular, Inc.Telescoping Catheter With Electromagnetic Coils for Imaging and Navigation During Cardiac Procedures
US2007025207430 Sep 20051 Nov 2007The Board Of Trustees Of The Leland Stanford JunioImaging Arrangements and Methods Therefor
US2007025527027 Abr 20061 Nov 2007Medtronic Vascular, Inc.Intraluminal guidance system using bioelectric impedance
US2007027068217 May 200622 Nov 2007The Gov't Of The U.S., As Represented By The Secretary Of Health & Human Services, N.I.H.Teniae coli guided navigation and registration for virtual colonoscopy
US2007029935113 Jun 200627 Dic 2007Doron HarlevNon-contact cardiac mapping, including resolution map
US2007029935213 Jun 200627 Dic 2007Doron HarlevNon-contact cardiac mapping, including moving catheter and multi-beat integration
US2007029935313 Jun 200627 Dic 2007Doron HarlevNon-contact cardiac mapping, including preprocessing
US200800154669 Jul 200717 Ene 2008Mayo Foundation For Medical Education And ResearchObtaining a tissue sample
US2008002449327 Jun 200731 Ene 2008Siemens Medical Solutions Usa, Inc.Systems and Methods of Direct Volume Rendering
US200800381976 Ago 200714 Feb 2008Siemens AktiengesellschaftMethod and apparatus for representing myocardial tissues in different states of damage
US2008005865630 Mar 20076 Mar 2008Costello Benedict JElectric tomography
US2008007114218 Sep 200620 Mar 2008Abhishek GattaniVisual navigation system for endoscopic surgery
US2008010353528 Dic 20071 May 2008Cameron Health, Inc.Implantable Medical Devices Including Selectable Notch Filter Circuits
US2008011811722 Nov 200622 May 2008Barco N.V.Virtual endoscopy
US2008012391019 Sep 200629 May 2008Bracco Imaging SpaMethod and system for providing accuracy evaluation of image guided surgery
US2008013280030 Nov 20065 Jun 2008Hettrick Douglas ANovel medical methods and systems incorporating wireless monitoring
US2008018307230 Mar 200731 Jul 2008Robertson Timothy LContinuous field tomography
US2008020799730 Ene 200828 Ago 2008The Penn State Research FoundationMethod and apparatus for continuous guidance of endoscopy
US200802214259 Mar 200711 Sep 2008Olson Eric SSystem and method for local deformable registration of a catheter navigation system to image data or a model
US2008022143812 Mar 200811 Sep 2008Chen Luke YAutomated catalog and system for correction of inhomogeneous fields
US2008024302523 Dic 20042 Oct 2008Nils HolmstromMedical Device
US200802493752 Nov 20049 Oct 2008Martin ObelArrangement and Method for Evaluating Operational Effectiveness of Implantable Medical Electrode Leads for Different Lead Placements
US2008025547029 Dic 200616 Oct 2008Hauck John AContact sensor and sheath exit sensor
US2008031929720 Jun 200725 Dic 2008Kenneth DanehornElectrode catheter positioning system
US2009001743015 May 200815 Ene 2009Stryker Trauma GmbhVirtual surgical training tool
US200900631188 Oct 20055 Mar 2009Frank DachilleSystems and methods for interactive navigation and visualization of medical images
US2009009385731 Jul 20089 Abr 2009Markowitz H TobySystem and method to evaluate electrode position and spacing
US2009009961918 Ago 200816 Abr 2009Lessmeier Timothy JMethod for optimizing CRT therapy
US2009010379315 Mar 200623 Abr 2009David BorlandMethods, systems, and computer program products for processing three-dimensional image data to render an image from a viewpoint within or beyond an occluding region of the image data
US2009012657526 Dic 200621 May 2009Lg Chem, Ltd.Apparatus for separating oil from blow-by gas of engine
US2009012947716 Oct 200821 May 2009Shun-An YangMethods and Apparatus for Fast Signal Acquisition in a Digital Video Receiver
US2009013195529 Sep 200521 May 2009Corindus Ltd.Methods and apparatuses for treatment of hollow organs
US2009019238130 Ene 200930 Jul 2009Brockway Brian PMinimally Invasive Physiologic Parameter Recorder and Introducer System
US2009021190911 Mar 200927 Ago 2009Bruce NesbittMarked precoated medical device and method of manufacturing same
US200902278616 Mar 200810 Sep 2009Vida Diagnostics, Inc.Systems and methods for navigation within a branched structure of a body
US200902539762 Abr 20088 Oct 2009Rhythmia Medical, Inc.Intracardiac Tracking System
US200902539857 Abr 20088 Oct 2009Magnetecs, Inc.Apparatus and method for lorentz-active sheath display and control of surgical tools
US2009026210915 Abr 200922 Oct 2009Markowitz H TobyIllustrating a three-dimensional nature of a data set on a two-dimensional display
US2009026297913 Abr 200922 Oct 2009Markowitz H TobyDetermining a Material Flow Characteristic in a Structure
US2009026298013 Abr 200922 Oct 2009Markowitz H TobyMethod and Apparatus for Determining Tracking a Virtual Point Defined Relative to a Tracked Member
US2009026298214 Abr 200922 Oct 2009Markowitz H TobyDetermining a Location of a Member
US200902629928 May 200822 Oct 2009Markowitz H TobyMethod And Apparatus For Mapping A Structure
US200902647279 Abr 200922 Oct 2009Markowitz H TobyMethod and apparatus for mapping a structure
US200902647389 Abr 200922 Oct 2009Markowitz H TobyMethod and apparatus for mapping a structure
US200902647399 Abr 200922 Oct 2009Markowitz H TobyDetermining a position of a member within a sheath
US2009026474013 Abr 200922 Oct 2009Markowitz H TobyLocating an Introducer
US2009026474114 Abr 200922 Oct 2009Markowitz H TobyDetermining a Size of A Representation of A Tracked Member
US2009026474214 Abr 200922 Oct 2009Markowitz H TobyDetermining and Illustrating a Structure
US2009026474314 Abr 200922 Oct 2009Markowitz H TobyInterference Blocking and Frequency Selection
US2009026474414 Abr 200922 Oct 2009Markowitz H TobyReference Structure for a Tracking System
US2009026474514 Abr 200922 Oct 2009Markowitz H TobyMethod and Apparatus To Synchronize a Location Determination in a Structure With a Characteristic of the Structure
US2009026474615 Abr 200922 Oct 2009Markowitz H TobyTracking a guide member
US2009026474715 Abr 200922 Oct 2009Markowitz H TobyDetermining and illustrating tracking system members
US2009026474815 Abr 200922 Oct 2009Markowitz H TobyVolumetrically illustrating a structure
US2009026474915 Abr 200922 Oct 2009Markowitz H TobyIdentifying a structure for cannulation
US2009026475015 Abr 200922 Oct 2009Markowitz H TobyLocating a member in a structure
US2009026475115 Abr 200922 Oct 2009Markowitz H TobyDetermining the position of an electrode relative to an insulative cover
US200902647528 May 200822 Oct 2009Markowitz H TobyMethod And Apparatus For Mapping A Structure
US2009026477713 Abr 200922 Oct 2009Markowitz H TobyDetermining a Flow Characteristic of a Material in a Structure
US2009026477814 Abr 200922 Oct 2009Markowitz H TobyUni-Polar and Bi-Polar Switchable Tracking System between
US2009026512815 Abr 200922 Oct 2009Markowitz H TobyCorrecting for distortion in a tracking system
US2009026777313 Abr 200929 Oct 2009Markowitz H TobyMultiple Sensor for Structure Identification
US2009029700117 Abr 20093 Dic 2009Markowitz H TobyMethod And Apparatus For Mapping A Structure
US200903067321 Abr 200910 Dic 2009Pacesetter, Inc.Cardiac resynchronization therapy optimization using electromechanical delay from realtime electrode motion tracking
US2010000472426 Jun 20097 Ene 2010Medtronic, Inc.Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
US2010003029821 Sep 20074 Feb 2010Koninklijke Philips Electronics N.V.Tissue stimulation method and apparatus
US2010015257116 Dic 200817 Jun 2010Medtronic Navigation, IncCombination of electromagnetic and electropotential localization
US2011005429327 Jul 20103 Mar 2011Medtronic, Inc.Combination Localization System
US2011005430427 Jul 20103 Mar 2011Medtronic, Inc.Combination Localization System
US2011010620330 Oct 20095 May 2011Medtronic, Inc.System and method to evaluate electrode position and spacing
US2012012347417 Nov 201117 May 2012Zajac Eric SAdjustable suture-button construct for ankle syndesmosis repair
US2012012354117 Nov 201117 May 2012Ricardo AlbertorioAdjustable suture-button constructs for ligament reconstruction
US2012013023226 Ene 201224 May 2012Regents Of The University Of MinnesotaIllustrating a Three-Dimensional Nature of a Data Set on a Two-Dimensional Display
US2012019099320 Mar 201226 Jul 2012Medtronic, Inc.Locating an indicator
US201202208607 May 201230 Ago 2012Medtronic Navigation, Inc.Combination of Electromagnetic and Electropotential Localization
US201202261108 Mar 20126 Sep 2012Medtronic, Inc.Multiple Sensor Input for Structure Identification
CN101711125A28 Dic 200719 May 2010美敦力公司Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
CN102056537A17 Abr 200911 May 2011明尼苏达大学董事会Method and apparatus for mapping a structure
CN102118994A17 Abr 20096 Jul 2011明尼苏达大学董事会Method and apparatus for mapping a structure
EP0363117A12 Oct 198911 Abr 1990Baxter International Inc.A position-monitoring flow-directed catheter and method
EP1393674A127 Ago 20033 Mar 2004Biosense Webster, Inc.Catheter and method for mapping Purkinje fibers
EP1421913A124 Oct 200326 May 2004Surgical Navigation Technologies, Inc.Image guided catheter navigation system for cardiac surgery
EP2136706A128 Dic 200730 Dic 2009Medtronic, Inc.Chronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
EP2276402A117 Abr 200926 Ene 2011Medtronic, Inc.Method and apparatus for mapping a structure
WO1998048722A18 Abr 19985 Nov 1998American Cardiac Ablation Co., Inc.Catheter positioning system
WO2001034050A226 Oct 200017 May 2001Medtronic Surgical Navigation TechnologiesSystem for translation of electromagnetic and optical localization systems
WO2002064040A211 Feb 200222 Ago 2002Medtronic, Inc.System and method for placing an implantable medical device within a living body
WO2005112836A218 May 20051 Dic 2005Johns Hopkins UniversityInterventional devices for chronic total occlusion recanalization under mri guidance
WO2006042039A26 Oct 200520 Abr 2006Proteus Biomedical, Inc.Continuous field tomography
WO2006117773A13 May 20059 Nov 2006Paieon Inc.Method and apparatus for positioning a biventrivular pacemaker lead and electrode
WO2007067945A27 Dic 200614 Jun 2007Medtronic, IncMethod for guiding a medical device
WO2007111542A127 Mar 20064 Oct 2007St. Jude Medical AbMedical system for monitoring and localisation of electrode leads in the heart
WO2007136451A222 Mar 200729 Nov 2007Exxonmobil Upstream Research CompanyDetermining orientation for seafloor electromagnetic receivers
WO2008108901A828 Dic 200718 Feb 2010Medtronic, IncChronically-implantable active fixation medical electrical leads and related methods for non-fluoroscopic implantation
WO2008147961A123 May 20084 Dic 2008Biosense Webster, Inc.Magnetically guided catheter with concentric needle port
WO2009086392A123 Dic 20089 Jul 2009Medtronic, Inc.System and method to evaluate electrode position and spacing
WO2009126575A16 Abr 200915 Oct 2009Magnetecs, Inc.Apparatus and method for lorentz-active sheath display and control of surgical tools
WO2009129475A117 Abr 200922 Oct 2009Medtronic, Inc.Method and apparatus for mapping a structure
WO2009129477A117 Abr 200922 Oct 2009Medtronic, Inc.Method and apparatus for mapping a structure
WO2009129484A117 Abr 200922 Oct 2009Medtronic, Inc.Method and apparatus for mapping a structure
WO2010074986A110 Dic 20091 Jul 2010Medtronic Navigation, Inc.Combination of electromagnetic and electropotential localization
WO2010118314A19 Abr 201014 Oct 2010Medtronic, Inc.System and method for determining sheath location
WO2011025708A220 Ago 20103 Mar 2011Medtronic, Inc.Combination localization system
WO2011026077A231 Ago 20103 Mar 2011Medtronic, Inc.Combination localization system
Otras citas
Referencia
1"EnSite NavX(TM) Navigation & Visualization Technology." 3 pages, St. Jude Medical. http://www.sjmprofessional.com/Products/US/Mapping-and-Visualization/EnSite-NavX-Navigation-and-Visualization-Technology.aspx Web. Accessed Jun. 19, 2009.
2"EnSite NavX™ Navigation & Visualization Technology." 3 pages, St. Jude Medical. http://www.sjmprofessional.com/Products/US/Mapping-and-Visualization/EnSite-NavX-Navigation-and-Visualization-Technology.aspx Web. Accessed Jun. 19, 2009.
3"Local Lisa® Intracardiac Navigation System Model 9670000/9670025." Technical Manual Version 1.2, Chapter 1, pp. 1-19. 2004.
4Birkfellner, Wolfgang, et al. "Calibration of Tracking Systems in a Surgical Environment," IEEE Transactions on Medical Imaginge, IEEE Service Center, Piscataway, NJ, US, vol. 17, No. 5. (Oct. 1, 1998) XP011035767. ISSN: 0278-0062 the whole document.
5Brenner, David J., Ph.D., "Computed Tomography-An Increasing Source of Radiation Exposure", The New England Journal of Medicine (Nov. 29, 2007), pp. 2277-2284.
6Brenner, David J., Ph.D., "Computed Tomography—An Increasing Source of Radiation Exposure", The New England Journal of Medicine (Nov. 29, 2007), pp. 2277-2284.
7Gepstein, Lior, M.D., "A Novel Method for Nonfluoroscopic Catheter-Based Electroanatomical Mapping of the Heart, In Vitro and In Vivo Accuracy Results", American Heart Association, Learn and Live, Circulation (1997), http://circ.ahajournals.org/cgi/content/abstract/95/6/1611 printed Oct. 2, 2008.
8Hubert-Tremblay, Vincent, et al. "Octree indexing of DICOM images for voxel number reduction and improvement of Monte Carolo simulation computing efficiency," Medical Physics, AIP, Melville, NY, US, vol. 33, No. 8, (Jul. 21, 2006) pp. 2819-2831, XP012092212, ISSN: 0094-2405, DOI: 10.1118/1.2214305 pp. 2820-2821.
9International Preliminary Report on Patentability and Written Opinion for PCT/US2009/0400984 mailed Oct. 28, 2010, claiming benefit of U.S. Appl. No. 12/117,549, filed May 8, 2008.
10International Preliminary Report on Patentability and Written Opinion for PCT/US2009/040979 mailed Oct. 28, 2010 claiming benefit of U.S. Appl. No. 12/117,537, filed May 8, 2008.
11International Preliminary Report on Patentability and Written Opinion for PCT/US2009/040998 mailed Oct. 28, 2010, 2009 claiming benefit of U.S. Appl. No. 12/421,332, filed Apr. 9, 2009; which claims priority to U.S. Appl. No. 61/105,957, filed Oct. 16, 2008; U.S. Appl. No. 12/117,549, filed May 8, 2008.
12International Preliminary Report on Patentability and Written Opinion for PCT/US2010/047241 mailed Mar. 15, 2012 claiming benefit of U.S. Appl. No. 12/844,065, filed Jul. 27, 2010.
13International Preliminary Report on Patentability and Written Opinion mailed Oct. 29, 2009 for PCT/US2007/089087, of which U.S. Appl. No. 12/492,906, filed Jun. 26, 2009 claims benefit.
14International Preliminary Report on Patentability mailed Oct. 11, 2011 for PCT/US2010/030534 claming benefit of U.S. Appl. No. 12/421,375, filed Apr. 9, 2009.
15International Search Report and Written Opinion for PCT/US2008/088189 mailed Apr. 3, 2009, claiming benefit of U.S. Appl. No. 12/183,796, filed Jul. 31, 2008; and claims priority to U.S. Appl. No. 11/966,382, filed Dec. 28, 2007.
16International Search Report and Written Opinion for PCT/US2009/0400984 mailed Sep. 21, 2009, claiming benefit of U.S. Appl. No. 12/117,549, filed May 8, 2008.
17International Search Report and Written Opinion for PCT/US2009/040998 mailed Jul. 29, 2009 claiming benefit of U.S. Appl. No. 12/421,332, filed Apr. 9, 2009; which claims priority to U.S. Appl. No. 61/105,957, filed Oct. 16, 2008; U.S. Appl. No. 12/117,549, filed May 8, 2008.
18International Search Report and Written Opinion for PCT/US2009/067486 mailed May 4, 2010, claiming benefit of U.S. Appl. No. 12/336,085, filed Dec. 16, 2008.
19International Search Report and Written Opinion mailed Dec. 6, 2010 for PCT/US2010/051248, which claims benefit of U.S. Appl. No. 12/609,734 filed Oct. 30, 2009.
20International Search Report and Written Opinon for PCT/US2009/040979 mailed Sep. 21, 2009 claiming benefit of U.S. Appl. No. 12/117,537, filed May 8, 2008.
21International Search Report and Written Opinon mailed Jul. 25, 2011 for PCT/US2010/047241 claiming benefit of U.S. Appl. No. 12/844,065, filed Jul. 27, 2010.
22International Search Report for PCT/US2007/089087 mailed Jul. 9, 2008, of which U.S. Appl. No. 12/492,906, filed Jun. 26, 2009 claims benefit.
23International Search Report mailed Sep. 13, 2010 for PCT/US2010/030534 claming benefit of U.S. Appl. No. 12/421,375, filed Apr. 9, 2009.
24Invitation to Pay Additional Fees for PCT/US2009/0400984 mailed Jul. 30, 2009, claiming benefit of U.S. Appl. No. 12/117,549, filed May 8, 2008.
25Invitation to Pay Additional Fees for PCT/US2009/040979 mailed Jul. 30, 2009 claiming benefit of U.S. Appl. No. 12/117,537, filed May 8, 2008.
26Invitation to Pay Additional Fees for PCT/US2009/067486 mailed Mar. 5, 2010, claiming benefit of U.S. Appl. No. 12/336,085, filed Dec. 16, 2008.
27Invitation to Pay Additional Fees for PCT/US2010/047241 mailed Jan. 10, 2011, claiming benefit of U.S. Appl. No. 12/844,065, filed Jul. 27, 2010.
28Invitation to Pay Additional Fees mailed Jul. 7, 2010 for PCT/US2010/030534 claiming benefit of U.S. Appl. No. 12/421,375, filed Apr. 9, 2009.
29Invitation to Pay Additional Fees mailed Jul. 7, 2010 for PCT/US2010/030534 claming benefit of U.S. Appl. No. 12/421,375, filed Apr. 9, 2009.
30Jiang, Yuan. "An Impedance-Based Catheter Poisitioning System for Cardiac Mapping and Navigation." IEEE Transactions on Biomedical Engineering, (Aug. 2009) pp. 1963-1970, vol. 56, No. 8.
31Markowitz, Toby, et al., "Unleaded: The Fluoroless 3D Lead Implant", Presented at Heart Rhythm Society, Denver, CO, (May 2007) 1 pg.
32Markowitz, Toby, et al., Abstract Submission, Unleaded: "The Fluoroless 3D Lead Implant", Mar. 2007 2 pgs.
33Milstein, S. et al., "Initial Clinical Results of Non-Fluoroscopic Pacemaker Lead Implantation." (poster presentation) May 14-17, 2008. 1 pg.
34Milstein, S. et al., "Initial Clinical Results of Non-Fluoroscopic Pacemaker Lead Implantation." (pre-presentation abstract) May 14-17, 2008. 2 pgs.
35Nelder, J.A., et al. "A simplex method for function minimization." vol. 7, Issue 4, (1965) pp. 308-313.The Computer Journal.
36Savage, George, M.D., "Electric Tomography (ET)-A Novel Method for Assessing Myocardial Motion and Cardiac Performance", Heart Rhytm Society, Denver, CO (May 9-12, 2007) 1 pg.
37Savage, George, M.D., "Electric Tomography (ET)—A Novel Method for Assessing Myocardial Motion and Cardiac Performance", Heart Rhytm Society, Denver, CO (May 9-12, 2007) 1 pg.
38Wittkampf, Fred, H.M., et al., "LocaLisa: New Technique for Real-Time 3-Dimensional Localization of Regular Intracardiac Electrodes." Circulation Journal of the American Heart Association, 1999; 99; 13-12-1317.
39Wittkampf, Fred., H.M., et al. "Accuracy of the LocaLisa System in Catheter Ablation Procedures." Journal of Electrocardiology vol. 32 Supplement (1999). Heart Lung Institute, University Hospital Utrecht, The Netherlands.
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US910128512 Jun 201311 Ago 2015Medtronic, Inc.Reference structure for a tracking system
US91318728 Mar 201215 Sep 2015Medtronic, Inc.Multiple sensor input for structure identification
US917986014 Abr 200910 Nov 2015Medtronic, Inc.Determining a location of a member
US933292814 Abr 200910 May 2016Medtronic, Inc.Method and apparatus to synchronize a location determination in a structure with a characteristic of the structure
US961004531 Jul 20154 Abr 2017Medtronic, Inc.Detection of valid signals versus artifacts in a multichannel mapping system
US96620413 Jun 201330 May 2017Medtronic, Inc.Method and apparatus for mapping a structure
US973722331 Jul 201522 Ago 2017Medtronic, Inc.Determining onset of cardiac depolarization and repolarization waves for signal processing
WO2016183444A213 May 201617 Nov 2016Medtronic, Inc.Determining onset of cardiac depolarization and repolarization waves for signal processing
WO2017023393A113 May 20169 Feb 2017Medtronic, Inc.Identifying ambiguous cardiac signals for electrophysiologic mapping
Clasificaciones
Clasificación de EE.UU.128/897
Clasificación internacionalA61B19/00
Clasificación cooperativaG06K2209/057, G06K2209/05, A61B6/12, A61B5/063, A61B5/06, A61B5/0538, A61B5/053, A61B5/0422, A61B5/0215, A61B2034/2046, A61B2034/2053, A61B2034/2051, A61B2034/2072, A61B34/20
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Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:MARKOWITZ, H. TOBY;GIESE, CHAD;JANNICKE, JEFF;AND OTHERS;SIGNING DATES FROM 20090327 TO 20090408;REEL/FRAME:027372/0074