US9314644B2 - Methods and systems for thermally-induced renal neuromodulation - Google Patents
Methods and systems for thermally-induced renal neuromodulation Download PDFInfo
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- US9314644B2 US9314644B2 US12/147,154 US14715408A US9314644B2 US 9314644 B2 US9314644 B2 US 9314644B2 US 14715408 A US14715408 A US 14715408A US 9314644 B2 US9314644 B2 US 9314644B2
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Abstract
Description
where Ti is a measured temperature, Tavg is the average temperature, and N is the number of temperature records. Other averaging techniques, such as an exponential moving average can also be used. The calculation module 466 can also derive a rate of change for the measured temperature according to the following formula:
where Ti+1 is the temperature record number i+1, Ti is the previous temperature record, and Δt is the time difference between the two temperature records.
-
- (1) The measured temperature exceeds a maximum temperature threshold (e.g., about 70° to about 85° C.).
- (2) The average temperature derived from the measured temperature exceeds an average temperature threshold (e.g., about 65° C.).
- (3) The rate of change of the measured temperature exceeds a rate of change threshold.
- (4) The temperature rise over a period of time is below a minimum temperature change threshold while the field generator 110 (
FIG. 3A ) has non-zero output. Poor contact between theelectrode 108 and the wall can cause such a condition. - (5) A measured impedance exceeds an impedance threshold (e.g., <20 Ohms, or >500 Ohms).
- (6) A measured impedance exceeds a relative threshold (e.g., impedance decreases from a starting or baseline value and then rises above this baseline value).
ΔP=k×(T max −T avg)
where k is a user-selected or predetermined constant, Tmax is the maximum temperature threshold, and Tavg is the average temperature.
where Pmax is the maximum power level, and n is the number of cycles.
Claims (39)
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