USH1929H - Cardiac rhythm management system with lead impedance measurement - Google Patents
Cardiac rhythm management system with lead impedance measurement Download PDFInfo
- Publication number
- USH1929H USH1929H US09/185,457 US18545798A USH1929H US H1929 H USH1929 H US H1929H US 18545798 A US18545798 A US 18545798A US H1929 H USH1929 H US H1929H
- Authority
- US
- United States
- Prior art keywords
- lead impedance
- impedance measurement
- cardiac rhythm
- rhythm management
- voltage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
- A61N1/3706—Pacemaker parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
- A61N1/36521—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure the parameter being derived from measurement of an electrical impedance
Abstract
An implanted cardiac rhythm management device, such as a pacemaker (pacer) or defibrillator provides a lead impedance measurement of the effective resistance of the leadwire connecting the device to electrodes in the heart. The lead impedance measurement is based on the amount of a voltage droop of a capacitively coupled pacing output voltage pulse over a fixed period of time that is shorter than the duration of the pacing pulse. The lead impedance measurement avoids the need for performing a natural logarithm function by using a look-up table of precalculated scaled resistance values corresponding to particular amounts of voltage droop. The lead impedance measurement is enhanced by performing interpolation and correcting for manufacturing tolerances of the particular cardiac rhythm management device.
Description
This invention relates generally to cardiac rhythm management systems and particularly, but not by way of limitation, to a cardiac rhythm management system with a lead impedance measurement circuit.
When functioning properly, the human heart maintains its own intrinsic rhythm, and is capable of pumping adequate blood throughout the body's circulatory system. However, some people have irregular cardiac rhythms, referred to as cardiac arrhythmias. Such arrhythmias result in diminished blood circulation. One mode of treating cardiac arrhythmias is via drug therapy. Drugs are often effective at restoring normal heart rhythms. However, drug therapy is not always effective for treating arrhythmias of certain patients. For such patients, an alternative mode of treatment is needed. One such alternative mode of treatment includes the use of a cardiac rhythm management system. Such systems are often implanted in the patient and deliver therapy to the heart.
Cardiac rhythm management systems include, among other things, pacemakers, also referred to as pacers. Pacers deliver timed sequences of low energy electrical stimuli, called pace pulses, to the heart, such as via a transvenous leadwire having one or more electrodes disposed in the heart. Heart contractions are initiated in response to such pace pulses. By properly timing the delivery of pace pulses, the heart can be induced to contract in proper rhythm, greatly improving its efficiency as a pump. Pacers are often used to treat patients with bradyarrhythmias, that is, hearts that beat too slowly, or irregularly.
Cardiac rhythm management systems also include cardioverters or defibrillators that are capable of delivering higher energy electrical stimuli to the heart. Defibrillators are often used to treat patients with tachyarrhythmias, that is, hearts that beat too quickly. Such too-fast heart rhythms also cause diminished blood circulation because the heart isn't allowed sufficient time to fill with blood before contracting to expel the blood. Such pumping by the heart is inefficient. A defibrillator is capable of delivering an high energy electrical stimulus that is sometimes referred to as a countershock. The countershock interrupts the tachyarrhythmia, allowing the heart to reestablish a normal rhythm for the efficient pumping of blood. In addition to pacers, cardiac rhythm management systems also include, among other things, pacer/defibrillators that combine the functions of pacers and defibrillators, drug delivery devices, and any other systems or devices for diagnosing or treating cardiac arrhythmias.
One problem that arises in cardiac rhythm management devices is in determining lead impedance, that is, the effective resistance of the leadwire that couples the cardiac rhythm management device to the heart for delivering the electrical pacing pulses at electrodes within the heart. The value of the lead impedance provides useful information. For example, an extremely low lead impedance value may indicate a short circuit between the pacing electrodes. An extremely large lead impedance value may indicate an open circuit such as, for example, resulting from a leadwire that has become disconnected from the cardiac rhythm management device. Both defective leadwire conditions must be detected and remedied if the cardiac rhythm management device is to provide effective pacing therapy to the heart.
It is possible to calculate lead impedance based on a measurement of voltage droop from a capacitively coupled pacing pulse delivered to the heart. However, a lead impedance measurement based on measured pacing voltage droop typically requires a complicated natural logarithm function, ln(), to be performed. Because of the difficulty associated with performing a complex natural logarithm function, ln(), there is a need for other techniques of measuring lead impedance that avoid performing a complex natural logarithm, ln(), function.
The present system provides a lead impedance measurement based on measured pacing voltage droop, but which does not require a complex natural logarithm function to be performed at the time of the lead impedance measurement. This allows the lead impedance measurement to be performed completely within an implanted cardiac rhythm management device that does not need to incorporate circuits for performing the natural logarithm function. Because lead impedance measurements can be made entirely within the implanted cardiac rhythm management device, there is no need to communicate data to an external programmer for performing a natural logarithm function and determining the lead impedance in the external programmer.
Because lead impedance is measured entirely within the cardiac rhythm management device, the cardiac rhythm management device is capable of automatically performing several desirable functions. In one embodiment, performing the lead impedance measurement entirely within the implanted cardiac rhythm management device allows the implantable device to perform an Exit Shipping State function. In one such example, the implantable cardiac rhythm management device is placed in a shipping state when shipped from a manufacturing facility. Upon detecting a substantial decrease in lead impedance (or an increase in voltage droop at the lead terminals) from the open-circuit condition in which it is shipped, the cardiac rhythm management device automatically exits the shipping state and begins delivering pacing pulses at nominal pacing conditions (e.g., VVI mode, 3.5 Volt and 0.4 millisecond pace pulses).
In another embodiment, performing the lead impedance measurement entirely within the implanted cardiac rhythm management device allows the device to perform an Auto Lead Configuration function. In one such example, the implanted cardiac rhythm management device automatically switches from bipolar pacing (i.e., delivering pacing pulses between electrodes that are both disposed on a distal tip of the leadwire in the heart) to unipolar pacing (i.e., delivering pacing pulses between an electrode disposed on the distal tip of the leadwire in the heart, and a second electrode located on the housing of the implanted cardiac rhythm management device implanted in the pectoral region or elsewhere). This allows pacing pulses to continue to be provided from a good electrode in the heart if the other electrode in the heart becomes disconnected from the cardiac rhythm management device, such as by a break in the leadwire connecting that electrode to the cardiac rhythm management device.
In the drawings, like numerals describe substantially similar components throughout the several views.
FIG. 1 is a schematic diagram illustrating generally a cardiac rhythm management device and an environment in which it is used.
FIG. 2 is a schematic/block diagram illustrating a portion of a cardiac rhythm management device in more detail.
FIG. 3 illustrates portions of a lead impedance measurement circuit.
FIG. 4 is a signal graph illustrating generally the magnitude of a pacing voltage VEE and the magnitude of an output voltage vz of a gain circuit as a function of time.
FIG. 5 is a flow chart illustrating generally one method of using a cardiac rhythm management system and a lead impedance measurement circuit to obtain lead impedance measurements.
In the drawings that accompany the following detailed description, like numerals describe substantially similar components throughout the several views.
This document describes a cardiac rhythm management system including a lead impedance measurement system. FIG. 1 is a schematic diagram illustrating a cardiac rhythm management system 100 including a cardiac rhythm management device 105 coupled to a heart 110 via a leadwire 115. Leadwire 115 includes electrodes, such as tip electrode 120A and ring electrode 120B for delivering bipolar pacing pulses therebetween.
FIG. 2 illustrates a portion of device 105 in more detail. Device 105 includes a therapy circuit 200 that generates a pacing voltage VEE at node 205. The pacing voltage VEE is stored across a storage capacitor 210 for delivering pacing pulses to heart 110 through a pacing switch 215 and a coupling capacitor 220. In FIG. 2, resistance 225 represents the lead impedance seen by device 105. Resistance 225 includes the impedance of leadwire 115 in series with the impedance of the heart tissue and body fluids between tip electrode 120A and ring electrode 120B. A lead impedance measurement circuit 230 is coupled to receive the pacing voltage VEE at node 205.
FIG. 3 illustrates portions of lead impedance measurement circuit 230 in more detail. In FIG. 3, the pacing voltage VEE is received by a switched-capacitor gain circuit 300 (in this document, "gain" is understood to refer also to attenuation). Gain circuit 300 includes input capacitor 305 and feedback capacitor 310. Switch 307 is turned on at the beginning of a pacing pulse and is turned off after a fixed time period that is shorter than duration of the pacing pulse. Gain circuit 300 provides an output voltage vz at node 315 that is received at the input of analog-to-digital (A/D) converter 320. A/D converter 320 converts the voltage vZ into a digital value nZ, which is provided to a processor 330 for carrying out calculations for obtaining the desired lead impedance, as described below.
FIG. 4 is a signal graph illustrating the magnitude of pacing voltage VEE and the magnitude of output voltage vz of gain circuit 300 as a function of time. At time t0, therapy circuit 200 begins charging node 205 toward the programmed acing voltage VEE,0. At time t1, pacing switch 215 closes, discharging storage capacitor 210 through coupling capacitor 220 and resistance 225. In FIG. 4, the magnitude of the pacing voltage VEE accordingly begins to change, drooping from VEE,0 as storage capacitor 210 is being discharged during delivery of the pacing energy. At time t3, pacing switch 215 opens, and the pacing voltage VEE in FIG. 4 has drooped to VEE,1. After time t3, therapy circuit 200 begins recharging storage capacitor 210 toward the programmed pacing voltage VEE,0. Before time t1, the output voltage vz of gain circuit 300 is held at a reference potential, such as by autozeroing (i.e., closing the feedback loop around) operational amplifier 325. Between time t1 and t2, the output voltage vz tracks the droop of pacing voltage VEE. At time t2, the output voltage vz1 provides to A/D converter 320 a measured indication of the droop of pacing voltage VEE. The A/D converter 320 converts the output voltage vz1 to the digital value nz, from which an indication of the lead impedance can be obtained. After time t3, the output voltage vz of gain circuit 300 is held at a reference potential, such as by autozeroing operational amplifier 325.
FIG. 5 is a flow chart illustrating using system 100 and lead impedance measurement circuit 230 to obtain lead impedance measurements. At step 500,system 100 provides a measurement at node 315 of a voltage droop, Δvz, that is based on the voltage droop of pacing voltage VEE during issuance of a pacing pulse. At step 505, the voltage droop measurement at node 315 is converted to a digital value, Δnz, at the output of A/D converter 320. At step 510, system 100 looks up a scaled resistance, Rs, in a look-up table. At step 515, an interpolated resistance Rsi is calculated based on adjacent values of the scaled resistance Rs in the look-up table. At step 520, a correction factor is applied to the interpolated resistance Rsi to account for manufacturing tolerances, resulting in a corrected lead impedance measurement Rsic.
Equation 2 represents the value R225 of lead resistance 225 obtained by solving Equation 1, and making an appropriate substitution for the change in the digital value, Δnz, at the output of A/D converter 320. ##EQU2##
In Equation 2, Kc =C220 /(C210 +C220), and the factor 0.7/256 represents the input voltage range of A/D converter 320 of 0.7 Volts, divided by its quantized resolution, which, in this case, is 256 steps for an 8-bit A/D converter 320. The gain of gain circuit 300 is adjusted, along with the programmed pacing voltage VEE,0 and the duration, t, of the lead impedance measurement (t=t2 -t1), to ensure adequate voltage droop Δvz at node 315 over the range of impedance to be measured (e.g., 100 to 2500 ohms).
Equation 2 requires a natural logarithm function, ln(), which is difficult to perform in a typical microcontroller in an implanted cardiac rhythm management device 105. As a result, while Equation 2 is appropriate for determining the lead impedance value R225 in an external programmer, it is difficult to use Equation 2 within an implanted cardiac rhythm management device 105 to determine the lead impedance value R225. One aspect of the invention avoids using the natural logarithm function, ln(), of Equation 2 by using instead at least one lookup table. A lookup table is easier to implement on processor 330 within implanted cardiac rhythm management device 105 than a natural logarithm function, ln().
Tables 1 and 2 illustrate examples of such look-up tables, which are suitable for implementation on processor 330 within cardiac rhythm management device 105.
TABLE 1 ______________________________________ Lookup Table for Nominal Pacing Conditions (V.sub.EE,0 = 3.5 V, t.sub.3 - t.sub.1 = 0.35 milliseconds), Gain = 0.60. Index Δn.sub.z (counts) R.sub.s (counts) ______________________________________ 0 (lower) 9 237 1 15 141 2 27 77 3 47 43 4 81 24 5 130 14 6 190 9 7 (upper) 255 11 6 ______________________________________
TABLE 2 ______________________________________ Lookup Table for Default Lead Impedance Measurement Conditions (V.sub.EE,0 = 5.0 V, t.sub.3 - t.sub.1 = 0.35 milliseconds), Gain = 0.45. Index Δn.sub.z (counts) R.sub.S (counts)j ______________________________________ 0 (lower) 9 254 1 16 142 2 28 80 3 50 44 4 85 25 5 140 14 6 190 10 7 (upper) 245 `7 ______________________________________
Tables 1 and 2 correlate the digitized voltage droop Δnz output from A/D converter 320 to a scaled resistance, RS, measured in counts, which is an 8-bit representation of R225 (i.e., scaled to 12 ohms per count). The scaled resistances, RS, in Tables 1 and 2 are generated using Equation 2 to obtain an ideal value of R225. Then, these ideal values of R225 are scaled using Equation 3 to obtain the scaled resistances, RS, in Tables 1 and 2. ##EQU3##
In Equation 3, R225 is obtained using Equation 2, Ωq is the scaling factor of 12 ohms per count. The percentage multiplier of 0.96 more closely matches the logarithmic ideal curve of lead impedance to the piecewise linear approximation imposed by the finite and limited number of values (e.g., 8 values) of R225 included each of Tables 1 and 2. The percentage multiplier allows the error of the piecewise linear approximation to be distributed both positive and negative about the ideal lead impedance curve, thereby reducing the absolute error over most of the impedance measurement range to less than approximately +/-5%. The integer function rounds the resulting scaled resistance value, RS, to an 8-bit integer value, as illustrated in Tables 1 and 2.
Because only eight values of are provided in each of Tables 1 and 2, system 100 uses an interpolation technique to obtain scaled resistances RS that correspond to measured values of Δnz falling between the values of Δnz that are listed in Tables 1 and 2. One approach of performing the interpolation is illustrated by Equation 4. ##EQU4##
In Equation 4, Δnz is a measured value that may fall between upper and lower Δnz values listed, and corresponding upper and lower Rs values, listed in Tables 1 and 2. In Equation 4, Δnz1 is the lower table value, Δnzu is the upper table value, Rsu is the upper table value, Rs1 is the lower table value, and Rsi is the resulting interpolated value of the resistance scaled from R225.
In manufacturing a plurality of devices 105, the capacitance values of storage capacitor 210 and coupling capacitor 220, and the switch resistance value of pacing switch 215 may all vary from a particular one of devices 105 to a different one of devices 105 due to the manufacturing variations in these components from their nominal values. Because Equations 1 and 2 used the nominal values of these components, system 100 allows a correction to be made for such manufacturing variations as described below.
First, known resistances values Rz1 =200 Ω and Rz2 =1000 Ω of resistance 225 are measured by system 100 according to the techniques described above, obtaining resulting measured values Δnz1 and Δnz2. ##EQU5##
Equation 5 is similar to Equation 2, except the result Kx is scaled from R225 by a constant factor (i.e., Kx =(C·R225)÷t). Equation 5 results in K1, and K2, corresponding to Δnz1 and Δnz2, respectively. Next, Equation 6 is applied to the values K1 and K2 obtained from Equation 5 to obtain an offset correction factor ΔR. ##EQU6## Then, the offset correction factor ΔR is scaled according to Equation 7, to obtain a scaled offset correction factor ΔRs. ##EQU7## Furthermore, a slope correction factor, SCF, is obtained using Equation 8. ##EQU8## Next, using Equation 9, the slope correction factor, SCF, and the scaled offset correction factor, ΔRs, are applied to the interpolated measured lead resistances Rsi, obtained by system 100 from Equation 4. This results in the corrected measured lead resistance Rsic.
R.sub.sic =integer(R.sub.si ·SCF-ΔR.sub.s) (9)
The corrected measured lead impedance is converted to ohms by multiplying it by the scaling factor Ωq of 12 ohms per count. System 100 provides a measured lead impedance of greater than approximately +/-20% accuracy and 5% precision over a resistance range of 100 Ω to 2500 Ω.
Claims (1)
1. An implantable cardiac rhythm management system comprising:
a cardiac rhythm management device adapted for being implanted in a living organism;
a leadwire, coupled to the device, and providing at least one electrode;
a therapy circuit, coupled to the leadwire for providing electrical energy to the living organism;
a lead impedance measurement circuit, coupled to the leadwire and the therapy circuit, and providing an indication of a resistance of the leadwire based on a measured change in voltage resulting from the electrical energy provided to the living organism, wherein the lead impedance measurement is based on a predetermined set of resistances corresponding to a predetermined set of changes in voltage to which the measured change in voltage is compared;
an interpolation circuit providing a lead impedance measurement interpolated from values in the predetermined set of resistances and the predetermined set of changes in voltage; and
a correction factor circuit that is capable of adjusting the lead impedance measurement based on component variations from a nominal value in the device.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/185,457 USH1929H (en) | 1998-10-03 | 1998-10-03 | Cardiac rhythm management system with lead impedance measurement |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/185,457 USH1929H (en) | 1998-10-03 | 1998-10-03 | Cardiac rhythm management system with lead impedance measurement |
Publications (1)
Publication Number | Publication Date |
---|---|
USH1929H true USH1929H (en) | 2000-12-05 |
Family
ID=22681054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/185,457 Abandoned USH1929H (en) | 1998-10-03 | 1998-10-03 | Cardiac rhythm management system with lead impedance measurement |
Country Status (1)
Country | Link |
---|---|
US (1) | USH1929H (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040024424A1 (en) * | 2002-07-31 | 2004-02-05 | Propp Hal M. | Shock lead impedance measurement to ensure safe delivery of shock therapy to maintain circuit integrity |
US20040073266A1 (en) * | 2002-10-15 | 2004-04-15 | Haefner Paul A. | Automatic detection of defibrillation lead |
US20040111125A1 (en) * | 2002-12-09 | 2004-06-10 | Stessman Nicholas J. | Voltage independent measurement apparatus, system, and method |
US20040111130A1 (en) * | 2000-06-19 | 2004-06-10 | Hrdlicka Gregory A. | Trial neuro stimulator with lead diagnostics |
US20040147983A1 (en) * | 2002-10-30 | 2004-07-29 | Biotronik Gmbh & Co. Kg | Stimulation device with stimulation outcome monitoring |
US20080154139A1 (en) * | 2006-12-20 | 2008-06-26 | Shuros Allan C | Rate Adaptive Cardiac Pacing Systems and Methods |
US20140005755A1 (en) * | 2010-10-14 | 2014-01-02 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
US9550063B2 (en) | 2010-10-14 | 2017-01-24 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
-
1998
- 1998-10-03 US US09/185,457 patent/USH1929H/en not_active Abandoned
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040111130A1 (en) * | 2000-06-19 | 2004-06-10 | Hrdlicka Gregory A. | Trial neuro stimulator with lead diagnostics |
US7493159B2 (en) | 2000-06-19 | 2009-02-17 | Medtronic, Inc. | Trial neuro stimulator with lead diagnostics |
US7120493B2 (en) | 2002-07-31 | 2006-10-10 | Cardiac Pacemakers, Inc. | Shock lead impedance measurement to ensure safe delivery of shock therapy to maintain circuit integrity |
US20040024424A1 (en) * | 2002-07-31 | 2004-02-05 | Propp Hal M. | Shock lead impedance measurement to ensure safe delivery of shock therapy to maintain circuit integrity |
WO2004035134A2 (en) * | 2002-10-15 | 2004-04-29 | Cardiac Pacemakers, Inc. | Automatic detection of defibrillation lead |
WO2004035134A3 (en) * | 2002-10-15 | 2004-09-10 | Cardiac Pacemakers Inc | Automatic detection of defibrillation lead |
US20040073266A1 (en) * | 2002-10-15 | 2004-04-15 | Haefner Paul A. | Automatic detection of defibrillation lead |
US7450990B2 (en) * | 2002-10-30 | 2008-11-11 | Biotronik Gmbh & Co. Kg | Stimulation device with stimulation outcome monitoring |
US20040147983A1 (en) * | 2002-10-30 | 2004-07-29 | Biotronik Gmbh & Co. Kg | Stimulation device with stimulation outcome monitoring |
US7039464B2 (en) | 2002-12-09 | 2006-05-02 | Cardiac Pacemakers, Inc. | Voltage independent measurement apparatus, system, and method |
US20040111125A1 (en) * | 2002-12-09 | 2004-06-10 | Stessman Nicholas J. | Voltage independent measurement apparatus, system, and method |
US20080154139A1 (en) * | 2006-12-20 | 2008-06-26 | Shuros Allan C | Rate Adaptive Cardiac Pacing Systems and Methods |
US8406879B2 (en) * | 2006-12-20 | 2013-03-26 | Cardiac Pacemakers, Inc. | Rate adaptive cardiac pacing systems and methods |
US8738133B2 (en) | 2006-12-20 | 2014-05-27 | Cardiac Pacemakers, Inc. | Rate adaptive cardiac pacing systems and methods |
US20140005755A1 (en) * | 2010-10-14 | 2014-01-02 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
US9550063B2 (en) | 2010-10-14 | 2017-01-24 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
US9656097B2 (en) * | 2010-10-14 | 2017-05-23 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
US9821161B2 (en) | 2010-10-14 | 2017-11-21 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
US10035019B2 (en) | 2010-10-14 | 2018-07-31 | II Erich W. Wolf | Apparatus and method using near infrared reflectometry to reduce the effect of positional changes during spinal cord stimulation |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0341297B1 (en) | Sensing margin detectors for implantable electromedical devices | |
US5201865A (en) | Medical lead impedance measurement system | |
US6317628B1 (en) | Cardiac rhythm management system with painless defribillation lead impedance measurement | |
US4998974A (en) | Apparatus and method for antitachycardia pacing in dual chamber arrhythmia control system | |
EP0593745B1 (en) | Work-modulated pacing rate deceleration | |
US4899752A (en) | System for and method of therapeutic stimulation of a patient's heart | |
US5800466A (en) | Dynamic atrial detection sensitivity control in an implantable medical cardiac simulator | |
US20040073266A1 (en) | Automatic detection of defibrillation lead | |
EP0770411A2 (en) | Implantable cardiac stimulation device | |
US20040215259A1 (en) | Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia | |
US7120493B2 (en) | Shock lead impedance measurement to ensure safe delivery of shock therapy to maintain circuit integrity | |
CA2279840A1 (en) | Rate responsive cardiac pacemaker with peak impedance detection for rate control | |
WO1998046307A9 (en) | Dynamic atrial detection sensitivity control in an implantable medical cardiac stimulator | |
US20090076563A1 (en) | Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia | |
USH1929H (en) | Cardiac rhythm management system with lead impedance measurement | |
JPH06190067A (en) | Method and equipment for tolerance compensation for capacitor in heart stimulation device | |
US7983749B2 (en) | Cardiac rhythm management system with time-dependent frequency response | |
EP1385422A2 (en) | Method and system for monitoring heart failure using rate change dynamics | |
US5653740A (en) | Method and apparatus for induction of fibrillation | |
US6650937B2 (en) | Method and system for gradual cardiac training using an implantable medical device | |
EP2194865A1 (en) | Detecting worsening heart failure based on impedance measurements | |
US8676317B1 (en) | System and method for estimating defibrillation impedance based on low-voltage resistance measurements using an implantable medical device | |
WO1998010834A1 (en) | Method and apparatus for detecting amplitude loss in cardiac pacing pulses | |
US20060149320A1 (en) | Implantable cardiac stimulator |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: CARDIAC PACEMAKERS, INC, MINNESOTA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CITAK, BRAIN;REEL/FRAME:009563/0834 Effective date: 19981030 |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |