WO1990015568A3 - Apparatus and methods for noninvasive blood glucose monitoring - Google Patents

Apparatus and methods for noninvasive blood glucose monitoring

Info

Publication number
WO1990015568A3
WO1990015568A3 PCT/US1990/002940 US9002940W WO9015568A3 WO 1990015568 A3 WO1990015568 A3 WO 1990015568A3 US 9002940 W US9002940 W US 9002940W WO 9015568 A3 WO9015568 A3 WO 9015568A3
Authority
WO
WIPO (PCT)
Prior art keywords
glucose
receiving medium
membrane
medium
receiving
Prior art date
Application number
PCT/US1990/002940
Other languages
French (fr)
Other versions
WO1990015568A2 (en
Inventor
Theodore H Stanley
Charles Dewey Ebert
William I Higuchi
Jie Zhang
Original Assignee
Theodore H Stanley
Charles Dewey Ebert
William I Higuchi
Jie Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theodore H Stanley, Charles Dewey Ebert, William I Higuchi, Jie Zhang filed Critical Theodore H Stanley
Priority to KR1019910700129A priority Critical patent/KR920700014A/en
Publication of WO1990015568A2 publication Critical patent/WO1990015568A2/en
Publication of WO1990015568A3 publication Critical patent/WO1990015568A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

The present invention is directed to novel methods and apparatus for noninvasive blood glucose monitoring. Blood glucose is monitored noninvasively by correlation with amount of glucose which permeates an epithelial membrane (14), such as skin or a mucosal membrane, into a glucose receiving medium (12) over a specified time period. The glucose receiving (12) medium preferably includes a glucose permeation enhancer capable of increasing the glucose permeability across the epithelial membrane (14). The glucose receiving medium (12) is positioned against the epithelial membrane (14) so that the permeation enhancer alters the permeability of the membrane (14). After sufficient time delay, the glucose receiving medium (12) is removed and analyzed for the presence of glucose using conventional analytical techniques. The apparatus within the scope of the present invention includes means for supporting the glucose receiving medium. Such means for supporting the glucose receiving medium may include a housing (18) defining a receiving chamber therein which holds the glucose receiving medium (12) and an opening to the receiving chamber. The means for supporting the glucose receiving medium may also include a hydrogel. The apparatus also preferably includes means (20) for temporarily positioning the glucose receiving medium against the epithelial membrane.
PCT/US1990/002940 1989-06-02 1990-05-24 Apparatus and methods for noninvasive blood glucose monitoring WO1990015568A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019910700129A KR920700014A (en) 1989-06-02 1990-05-24 Non-Invasive Blood Glucose Testing Apparatus and Method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36036089A 1989-06-02 1989-06-02
US360,360 1989-06-02

Publications (2)

Publication Number Publication Date
WO1990015568A2 WO1990015568A2 (en) 1990-12-27
WO1990015568A3 true WO1990015568A3 (en) 1991-04-18

Family

ID=23417658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1990/002940 WO1990015568A2 (en) 1989-06-02 1990-05-24 Apparatus and methods for noninvasive blood glucose monitoring

Country Status (3)

Country Link
KR (1) KR920700014A (en)
AU (1) AU5825490A (en)
WO (1) WO1990015568A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8870810B2 (en) 1998-12-18 2014-10-28 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US9572527B2 (en) 2007-04-27 2017-02-21 Echo Therapeutics, Inc. Skin permeation device for analyte sensing or transdermal drug delivery

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6041253A (en) * 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
JP2002515786A (en) 1996-06-28 2002-05-28 ソントラ メディカル，エル．ピー． Ultrasound enhancement of transdermal delivery
US6602678B2 (en) * 1998-09-04 2003-08-05 Powderject Research Limited Non- or minimally invasive monitoring methods
AU6035299A (en) * 1998-09-09 2000-03-27 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
US6251083B1 (en) 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
US20040010185A1 (en) * 2002-07-11 2004-01-15 Optical Sensors, Inc. Method for measuring a physiologic parameter using a preferred site
WO2023172192A2 (en) * 2022-03-08 2023-09-14 Agency For Science, Technology And Research Epidermal biosensor

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250163A (en) * 1979-03-05 1981-02-10 Teijin Limited Method and preparation for administration to the mucosa of the oral or nasal cavity
US4321252A (en) * 1979-08-14 1982-03-23 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing ester derivatives of estradiol
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
WO1986000536A1 (en) * 1984-07-06 1986-01-30 Avery International Corporation Bandage for sustained delivery of drugs
US4746508A (en) * 1983-06-06 1988-05-24 Beth Israel Hospital Assn. Drug administration
US4819645A (en) * 1985-02-11 1989-04-11 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection method
US4889721A (en) * 1987-07-24 1989-12-26 Fujisawa Pharmaceutical Co., Ltd. Sustained-release percutaneous preparations

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250163A (en) * 1979-03-05 1981-02-10 Teijin Limited Method and preparation for administration to the mucosa of the oral or nasal cavity
US4321252A (en) * 1979-08-14 1982-03-23 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing ester derivatives of estradiol
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4746508A (en) * 1983-06-06 1988-05-24 Beth Israel Hospital Assn. Drug administration
WO1986000536A1 (en) * 1984-07-06 1986-01-30 Avery International Corporation Bandage for sustained delivery of drugs
US4819645A (en) * 1985-02-11 1989-04-11 The United States Of America As Represented By The Secretary Of The Army Dermal substance collection method
US4889721A (en) * 1987-07-24 1989-12-26 Fujisawa Pharmaceutical Co., Ltd. Sustained-release percutaneous preparations

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8870810B2 (en) 1998-12-18 2014-10-28 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US9572527B2 (en) 2007-04-27 2017-02-21 Echo Therapeutics, Inc. Skin permeation device for analyte sensing or transdermal drug delivery

Also Published As

Publication number Publication date
KR920700014A (en) 1992-02-19
WO1990015568A2 (en) 1990-12-27
AU5825490A (en) 1991-01-08

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