WO1991013902A3 - Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling - Google Patents

Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling Download PDF

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Publication number
WO1991013902A3
WO1991013902A3 PCT/US1991/001531 US9101531W WO9113902A3 WO 1991013902 A3 WO1991013902 A3 WO 1991013902A3 US 9101531 W US9101531 W US 9101531W WO 9113902 A3 WO9113902 A3 WO 9113902A3
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WO
WIPO (PCT)
Prior art keywords
oligodeoxynucleotides
site
radioactive labelling
specific functionalization
functionalization
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PCT/US1991/001531
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French (fr)
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WO1991013902A2 (en
Inventor
Sudhir Agrawal
Jinyan Tang
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Worcester Found Ex Biology
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Publication of WO1991013902A2 publication Critical patent/WO1991013902A2/en
Publication of WO1991013902A3 publication Critical patent/WO1991013902A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method of producing a synthetic oligodeoxynucleotide of selected nucleotide sequence which is internally labelled with a nonradioactive material at at least one selected location, as well as oligodeoxynucleotides produced by the method.
PCT/US1991/001531 1990-03-08 1991-03-06 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling WO1991013902A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US490,481 1990-03-08
US07/490,481 US5321131A (en) 1990-03-08 1990-03-08 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling

Publications (2)

Publication Number Publication Date
WO1991013902A2 WO1991013902A2 (en) 1991-09-19
WO1991013902A3 true WO1991013902A3 (en) 1992-01-23

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PCT/US1991/001531 WO1991013902A2 (en) 1990-03-08 1991-03-06 Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling

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US (4) US5321131A (en)
WO (1) WO1991013902A2 (en)

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