WO1992014423A1 - Middle expandable intervertebral disk implant and method - Google Patents

Middle expandable intervertebral disk implant and method Download PDF

Info

Publication number
WO1992014423A1
WO1992014423A1 PCT/US1992/001397 US9201397W WO9214423A1 WO 1992014423 A1 WO1992014423 A1 WO 1992014423A1 US 9201397 W US9201397 W US 9201397W WO 9214423 A1 WO9214423 A1 WO 9214423A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant
disk
rod
space
vertebrae
Prior art date
Application number
PCT/US1992/001397
Other languages
French (fr)
Inventor
Pisharodi Madhavan
Original Assignee
Pisharodi Madhavan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/659,758 external-priority patent/US5171278A/en
Application filed by Pisharodi Madhavan filed Critical Pisharodi Madhavan
Priority to DE69209494T priority Critical patent/DE69209494T2/en
Priority to CA002104391A priority patent/CA2104391C/en
Priority to US08/107,750 priority patent/US5390683A/en
Priority to JP50735292A priority patent/JP3390431B2/en
Priority to EP92907757A priority patent/EP0571555B1/en
Publication of WO1992014423A1 publication Critical patent/WO1992014423A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/446Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or elliptical cross-section substantially parallel to the axis of the spine, e.g. cylinders or frustocones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30721Accessories
    • A61F2/30744End caps, e.g. for closing an endoprosthetic cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30092Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30113Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30138Convex polygonal shapes
    • A61F2002/30143Convex polygonal shapes hexagonal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30138Convex polygonal shapes
    • A61F2002/30146Convex polygonal shapes octagonal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30138Convex polygonal shapes
    • A61F2002/30153Convex polygonal shapes rectangular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30138Convex polygonal shapes
    • A61F2002/30154Convex polygonal shapes square
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30225Flat cylinders, i.e. discs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30235Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30261Three-dimensional shapes parallelepipedal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/3028Three-dimensional shapes polyhedral different from parallelepipedal and pyramidal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30291Three-dimensional shapes spirally-coiled, i.e. having a 2D spiral cross-section
    • A61F2002/30293Cylindrical body made by spirally rolling up a sheet or a strip around itself
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30405Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by screwing complementary threads machined on the parts themselves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30433Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels, rivets or washers e.g. connecting screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30451Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30471Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30476Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism
    • A61F2002/30507Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism using a threaded locking member, e.g. a locking screw or a set screw
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30537Special structural features of bone or joint prostheses not otherwise provided for adjustable
    • A61F2002/30556Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30565Special structural features of bone or joint prostheses not otherwise provided for having spring elements
    • A61F2002/305732-D spiral springs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30579Special structural features of bone or joint prostheses not otherwise provided for with mechanically expandable devices, e.g. fixation devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30594Special structural features of bone or joint prostheses not otherwise provided for slotted, e.g. radial or meridian slot ending in a polar aperture, non-polar slots, horizontal or arcuate slots
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30599Special structural features of bone or joint prostheses not otherwise provided for stackable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30621Features concerning the anatomical functioning or articulation of the prosthetic joint
    • A61F2002/30624Hinged joint, e.g. with transverse axle restricting the movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30777Oblong apertures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30784Plurality of holes
    • A61F2002/30787Plurality of holes inclined obliquely with respect to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0041Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0058Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0091Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0006Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017Angular shapes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017Angular shapes
    • A61F2230/0019Angular shapes rectangular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017Angular shapes
    • A61F2230/0021Angular shapes square
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0082Three-dimensional shapes parallelepipedal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0091Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/0009Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006Additional features; Implant or prostheses properties not otherwise provided for modular
    • A61F2250/0063Nested prosthetic parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00023Titanium or titanium-based alloys, e.g. Ti-Ni alloys

Definitions

  • This invention relates to an intervertebral disk implant and a method of implanting same. More specifically, the present invention relates to cylindrical and rectangular disk implants which are expandable in the middle portion which are used alone or in various combinations for the purpose of spinal fusion.
  • the spine is a flexible structure comprised of thirty- three vertebrae separated and cushioned from each other by fibrous intervertebral disks. If the spine is injured or becomes diseased, surgical intervention involving removal of one or more disks, and fusion of the adjacent vertebrae, may be indicated. The more frequent injuries are in the lower lumbar and in the lower cervical regions.
  • a herniated disk in the neck and in the lumbar region continues to be a challenging field of medicine.
  • the classical treatment for a ruptured disk continues to be diskectomy, i.e., removal of the disk from between the vertebrae. In this process, all or a portion of the intervertebral disk is removed, leaving a defect which continues to bother the patients throughout the rest of their lives.
  • An additional procedure is to replace the disk space with a bone graft, usually bone chips cut from the patient's iliac crest, bringing about fusion of the vertebrae above and below the disk, eliminating the empty space between the vertebrae.
  • a diskectomy with fusion is a satisfactory procedure, though not ideal because the replaced bone does not have any of the functions of the cartilage tissue of the disk, i.e. no cushioning effect, and has complications because of several factors.
  • the bone plug used to pack the disk space does not conform to the shape of the disk because the disk bulges maximally in the center.
  • the disk space is wider in the middle and narrower at its anterior and posterior ends. Consequently, a bone plug having its maximum width at the center, e.g., one which is shaped to fit the space, cannot be inserted through the narrow mouth of the disk space. For this reason, the various bone plugs which are currently available commercially have only four contact points, i.e. at the front and back of the disk space.
  • Implants according to this invention include means for changing the shape of the implant to adapt to the shape of the disk
  • an intervertebral disk implant with a cylindrical body comprised of subunits
  • an implant having a
  • substantially rectangular body likewise comprised of subunits capable of radially outward expansion. Both are disk plugs expandable in, the middle portion to provide contact with substantially the entire area of the disk space against the vertebral bodies.
  • a method of fusing two adjacent vertebrae after removal of all or a portion of the disk from therebetween which comprises inserting a disk implant into the space from which the disk has been removed, expanding the middle portion of the implant outwardly in a radial direction, injecting cancellous bone chips into the disk space medial to the implant, and applying a physiologically compatible adhesive over the bone chips medial to the implant to close off the opening of the disk space.
  • Figure 1 is a projected view of one embodiment of the disk implant of the present invention.
  • Figure 2 is a cross sectional view of the disk implant of Fig. 1 taken along the line 2-2 in Fig. 1.
  • Figure 3 is a projected view of the central axis of the disk implant of Fig. 1 having the members coiled therearound removed therefrom.
  • Figure 4 is a projected view of the implant of Fig. 1 after expansion of the middle portion thereof.
  • Figure 5 is a projected, exploded view of a second embodiment of the disk implant of the present invention.
  • Figure 6 is a projected view of the implant of Fig. 5 showing that implant after expansion thereof.
  • Figure 7 is a top, plan view of a lumbar vertebra of a human patient having a top, plan view of the implant of
  • Fig. 6 superimposed thereon to show the spatial relationship of the implant to the adjacent vertebrae after insertion into the disk space.
  • Figure 8 is a projected view of another embodiment of the implant of the present invention.
  • Figure 9 is a projected view of the disk implant of Fig. 8 after expansion of the middle portion thereof.
  • Figure 10 is an exploded, projected view of a fourth embodiment of the implant of the present invention.
  • Figure 10A is a side view of two hinged members comprising the middle portion of the implant of Fig. 10 and removed therefrom.
  • Figure 11 is a projected view of a fifth embodiment of the disk implant of the present application.
  • Figure 12 is a cross sectional view of the disk implant of Fig. 11 taken along the line 12-12 in Fig. 11.
  • Figure 13 is a side view of the disk implant of Fig. 11 showing a portion broken away therefrom.
  • Figure 1 depicts a cylindrical embodiment of the disk implant of the present invention.
  • the disk implant 20 shown in that figure is comprised of a strong, thin non- porous material.
  • Suitable materials for the disk implant 20 include modified carbon, titanium, steel, metals and/or metal alloys having a memory (see below) , physiologically inert and/or medically compatible polymers such as a urethane or DELRIN® polymer, or any generally rigid, biologically compatible material used for surgical implants. It is also useful to use a material which is compatible with magnetic resonance imaging (MRI) procedures.
  • MRI magnetic resonance imaging
  • the disk implant 20 is comprised of a plurality of longitudinally aligned sections, or subunits 22, 24 and 26, and a screw 28 to which each section is mounted (as described below) is turned to cause differential, radially outward expansion of subunits 24 and 26.
  • the subunits 24 and 26 are preferably comprised of a material capable of maintaining spring tension and are mounted to and wound around an elongate longitudinal axis in the form of central rod 25 (see Figs. 2 and 3) integral with screwhead 28. Because of this structure, each of the subunits is conveniently referred to as including a coiled member as identified at reference numeral 32.
  • Each coiled member 32 is mounted to central rod 25 by welding, riveting, or by other manner depending upon the material(s) comprising the sheet 32 and central rod 25 as known in the art.
  • the central rod 25 is provided with a flat 23 to provide a stable surface for mounting of the member 32 thereto by, for instance, welding.
  • the coiled member 32 is beveled as at reference numeral 33 so as to provide a smooth, generally round exterior surface on each of the subunits 24 and 26 and to facilitate the sliding of the free end of coiled member 32 along the outside surface thereof as the subunits 24 and 26 are expanded radially outwardly as described below.
  • a Phillips head-type slot 18 is provided in the screwhead 28 for rotation of the rod 25 as described below, and the head 28 is provided with a plurality of teeth 19 for interdigitating with the reciprocal cavities in the lock nut 21 to prevent undesired rotation of central rod 25.
  • the Allen screws 30 are loosened to force lock nut 21 away from the end surface 27 of subunit 22 so that the teeth 19 on the head 28 of central rod 25 are disengaged from the cavities in lock nut 21 to allow rotation of screwhead 28 and rod 25.
  • rod 25 or lock nut 21 is comprised of a resilient, medically compatible polymer material which allows rotation of the teeth 19 past the cavities in lock nut 21 in one direction but not the other.
  • FIG. 2 The expanded shape of a section of the disk implant 20 is shown in Figure 2. Turning screwhead 28 and central rod 25 using the slot 18 expands the sections 24 and 26, which remain expanded due to the interaction of the teeth 19 and the cavities in lock nut 21 and the compression of the implant 20 between the bodies of the vertebrae above and below the implant 20 once inserted into the disk space. In other words, engagement of the free end of coiled member 32 by the adjacent vertebrae prevents the slipping of the free end of the coiled member 32 around the outside circumference of implant 20 such that members 32 do not "re-wind" after being expanded.
  • central rod 25 is provided with a portion 29 approximately mid-way between the ends thereof having a larger diameter than the rest of the central rod 25.
  • the subunits 24 and 26 are differentially expanded.
  • Turning screw 28 allows for maximal expansion of the subunit 26 and moderate expansion of the subunit 24 because the member 32 comprising subunit 26 is mounted to the rod 25 on the portion 29 of larger diameter while each of the members 32 comprising subunits 22 and 24 is mounted to central rod 25 between the portion 29 and the subunits 22.
  • Turning the central rod 25 uncoils the members 32 because each member 32 is attached to the central rod 25.
  • Figure 4 illustrates the cylindrical disk implant 20 in its radially expanded form.
  • Implant 56 is comprised of a single piece of metal, such as a titanium alloy, or medical grade polymeric plastic, such as DELRIN®, which is resilient and has a memory for the shape in which it is molded, shown in Fig. 6.
  • Implant 56 is molded in the same generally elongate, cylindrical shape as the implant 20 shown in Figs. 1-4, but is molded in a shape in which the middle portion 58 thereof is normally expanded radially outwardly from the central axis of the cylinder.
  • An elongate screw 60 is provided having two sets of threads 62 and 66 thereon, the former for engaging the threads 68 formed in the bore 70 extending longitudinally through implant 56, the latter for engaging a similarly formed set of threads located in the bore 70 at the other end of implant 56 and therefore not visible in Figures 5 and 6.
  • a slot 72 is formed in the head 74 of screw 60 for turning screw 60 to move the opposite ends 76a and 76b of implant 56 away from each other, thereby extending implant 56 and decreasing the radially outward expansion of the middle 58 thereof as shown in Fig. 5 for insertion into the disk space.
  • Longitudinal slots 75 are molded into implant 56 to form ribs 77 which flex to allow the extension and outward expansion of implant 56 in this manner.
  • FIG. 7 showing the implant 56 in place relative to the body 78 of an adjacent lumbar vertebra 80 illustrates how the apparatus of the present invention overcomes this limitation of prior implants.
  • the implant 56 is inserted into the disk space in an anterior-posterior (A-P) orientation, the dorsal spine 82 of vertebra 80 being pointed posterially.
  • A-P anterior-posterior
  • implant 56 occupies only a portion of the surface area of the vertebral body 78, the remainder of the area being occupied by that portion of the intervertebral disk (not shown) which is not removed during the diskectomy procedure (or, in a fusion procedure, this area is packed with cancellous bone chips) . Access to that area is from the posterior aspect of the disk medial to the implant.
  • the periphery 88 of vertebral body 78 is, as described above, thicker than the central portion 90 of body 78, further limiting access and creating an uneven surface on which the body 78 bears on the implant.
  • the implant 56 is stable in the A-P orientation shown.
  • FIG. 8 depicts a rectangular disk implant 31 constructed according to the present invention. Turning Phillips head 39 of screw 42 encapsulated in a sheath 44 (best shown in Fig. 9) formed in the hinged members 34 and 36 forming intermediate subunits in the same manner as the subunits, or sections, 24 and 26 of implant 20 causes the radially outward expansion of superior hinged members 34 superiorly and inferior hinged members 36 inferiorly.
  • the plug, or implant, 31 may be provided with four, eight, or even more of the hinged members 34 and 36 as shown at reference numerals 92 and 94 in Figure 10 and numeral 41 in Figures 11-13.
  • the expanded shape of the rectangular disk plug 31 is illustrated in Figure 9.
  • Hinged members 34 and 36 are secured to an end cap or subunit 33 by hinge 38 and to each other by hinge 46.
  • the end caps 33 are drawn closer together by movement along the threads of screw 42.
  • each respective member 34 and 36 abutting the end caps 33 are angled so as to create a force vector outwardly away from screw 42 when end cap 33 exerts pressure on the surface 48, the hinge 38 being mounted in the acute angle formed by surface 48 and end cap 33.
  • the tendency of this force vector to cause the members 34 and 36 to expand is increased by angling the face 50 of one member 34 or 36 in . the same direction as the angle in the surface 48.
  • the surface 52 of the opposed member 34 and 36 is similarly angled, but with a bearing surface 54 formed therein that is angled in the same direction as the angle in surface 48 and face 50 so that the face 50 rides upwardly onto bearing surface 54 to translate the opposed, end-to-end force vectors applied to end caps 33 by rotation of screw 42 into a force vector having a radially outward (from screw 42) component.
  • the hinged members 92 and 94 are mounted on pivot pins 96 to the first and second end members 90 and 98, respectively, as well as to each other, most of the pins 96 and all but two sets of the hinged members 92 and 94 being omitted from the figure for purposes of clarity.
  • the pivot pins 96 which mount members 92 and 94 to the ends 90 and 98 are received within the bores 100 and 102 formed in each end member 90 and 98, the bores 100 and 102 being numbered separately to draw attention to their arrangement on the end members 90 and 98.
  • the ears 104 on hinged members 92' and 94' are longer than the ears 106 on hinged members 92* ' and 94' ' and the bores 100 # for receiving the pivot pin 96 are located closer to the end surface 108 of end member 90 (and the corresponding end surface of end member 98 at the opposite end of implant 88) than the bores 102.
  • the strength of the implant 88 is significantly increased. Expansion of the middle portion of implant 88 is accomplished by turning the screw 112 using the hex head 114 formed at one end thereof, the other end of screw 112 being received by the threads 115 formed in the second end member 98.
  • the holes in the hinged members 92 and 94 in which pivot pins 96 reside are offset along the longitudinal axis of implant 88.
  • the offset holes are better shown in Figure 10A in which one pair of the members 92 and 94 is shown in side view removed from implant 88.
  • the direction of expansion is shown by the arrow 95 in Figure 10A and, as can be seen, the center holes 97 are offset outwardly (e.g., in the direction of arrow 95) relative to the holes 99 at the ends of hinged members 92 and 94 (e.g., in the ears 106).
  • a lock nut 116 having threads 118 formed in the outside surface thereof is received by the threads 120 formed in the bore 122 in end member 90 through which the screw 112 is received for preventing undesired rotation of screw 112.
  • Lock nut 116 is provided with a hex slot 124 to facilitate insertion and/or removal and hex slot 124 extends all the way through lock nut 116 and is of large enough size that a hex key can be inserted through slot 124 and into hex head 114 for turning screw 112 without adjustment of lock nut 116.
  • Another embodiment of the double-umbrella configuration of the implant of the present invention is shown at reference numeral 41 in Figures 11-13.
  • the implant 41 is generally cylindrical in shape, yet utilizes the hinged member 34 and 36 construction of implant 31 shown in Figures 8 and 9.
  • Figure 12 shows a projected view of the disk implant 41 shown in Figure 11 having the members 34 and 36 cut in section. This view shows how the hinged members 34 and 36 fit together in the unexpanded position due to their beveled sides 64, giving the implant 41 its generally cylindrical shape.
  • the sides 110 of the hinged members 92 and 94 of implant 88 are similarly beveled ( Figure 10) .
  • All of the disk implants of the present invention are expandable in the middle portion, i.e., the portion intermediate the ends, to contact substantially the entire anterior-posterior dimension of the disk space against the vertebral bodies as described above in connection with the description of Figure 7.
  • the plug is used in conjunction with intervertebral cancellous bone packing. Because of the support provided by the plug, until fusion is established, the cancellous bone pieces have a better chance of fusion due to the presence of the implant, and the bone pieces and the disk implant have a better chance of staying in the intervertebral disk space.
  • the plug is used to maintain the spacing between vertebrae and can be used in conjunction with intertransverse posterior lateral fusion.
  • the implant acts as a physiological support for the rest of the patient's life or until a bone fusion is established.
  • the disk implant of the present invention may have additional indications, e.g. short segment scoliosis, where the curvature of the spine can be corrected by distracting the vertebral bodies on the inside of the curvature. By expanding the middle portion of the plug inside the disk space, the vertebral bodies are distracted, thereby helping straighten the spinal column.
  • additional indications e.g. short segment scoliosis
  • diskectomy can be made minimally through one side exposure so that when the disk plug is inserted and expanded, it will occupy the empty space. Because there is no further movement at this disk space, the chance of recurrent disk herniation is minimized. Also, the likelihood of recurrent disk herniation due to opening and closing of the space on the side of the diskectomy is reduced because the disk plug closes this mouth. Consequently, in addition to the advantages of a one sided, simple diskectomy, the risk of recurrent disk herniation can be reduced.
  • the cylindrical 20, 41, 56, and 88 and rectangular 31 implants are inserted after a simple diskectomy. Ordinarily, the size of the disk implant is approximately 2.5 to 3.5 centimeters in length and 1.0 to 1.5 centimeters in height and width. The same plug in smaller dimensions is used in thoracic and cervical levels where indicated.
  • both the rectangular and the cylindrical implants have the common feature of being expandable in the middle without changing the diameter of the dimensions of the two ends. Consequently, surgery is performed as in simple diskectomy, and the disk is exposed through a small laminoto y. The disk material is removed and any nerve root compression is corrected. The posterior longitudinal ligament and disk cartilage are removed until the vertebral surfaces are exposed above and below the disk space. The shape of the disk space determines whether the disk plug used is cylindrical or rectangular. The disk plug is then inserted and hammered into place so that the anterior end of the disk plug almost touches the anterior longitudinal ligament. Subsequently, using a Phillips screwdriver, the posterior screw end is turned. This implant method also gives good distraction to the vertebral bodies.
  • cancellous bone chips are made into very fine particles and pumped into the disk space medial to the disk plug and packed into the space.
  • the posterior longitudinal ligament is intact to the opposite side and to the center of the disk space.
  • These cancellous bone chips are held tightly in place. Since the mouth of the disk space is closed with the disk plug, the risk of the cancellous bone chips coming out is minimized. Also, the disk plug prevents the opening and closing of the disk space, thus preventing the bone chips coming out.
  • a small amount of a physiologically compatible adhesive of a type known in the art is applied over the cancellous bone chips just medial to the disk plug to close off the remaining portion of the opening of the disk space. The patient should be able to ambulate soon after the surgery because of the stability given by the disk plug. Before narrowing of the disk space occurs, the cancellous bone chips will have started the fusion process.
  • a posterior lateral intertransverse fusion is also done in conjunction with the middle expandable disk plug.
  • the disk plug is applied as explained above and the posterior lateral fusion performed. Since the disk plug provides stability to the spine until the posterior lateral fusion is solid, the patient can ambulate soon after the surgery. This procedure also prevents the disk space narrowing, which is a common problem with posterior lateral fusion.

Abstract

Artificial disk implant and methods for implanting same, the implant having a member (32, 34, 36, 77, 92, 94) for adapting in size and shape to the anatomical space between vertebrae, and apparatus (25, 42, 60, 112) for expanding the implant in the middle portion thereof to conform to the space. In one embodiment, there is provided an artificial intervertebral disk implant having a cylindrical body (20, 41, 56, 88) comprised of cylindrical subunits (32, 34, 36, 92, 94) capable of expansion. In another embodiment, rectangular members (34, 36) or elongate ribs (77) capable of expansion are provided. The implant can be used alone or in various combinations for the purpose of spinal fusion.

Description

MIDDLE EXPANDABLE INTERVERTEBRAL DISK IMPLANT AND METHOD
BACKGROUND OF THE INVENTION
This invention relates to an intervertebral disk implant and a method of implanting same. More specifically, the present invention relates to cylindrical and rectangular disk implants which are expandable in the middle portion which are used alone or in various combinations for the purpose of spinal fusion.
The spine is a flexible structure comprised of thirty- three vertebrae separated and cushioned from each other by fibrous intervertebral disks. If the spine is injured or becomes diseased, surgical intervention involving removal of one or more disks, and fusion of the adjacent vertebrae, may be indicated. The more frequent injuries are in the lower lumbar and in the lower cervical regions.
Treatment of a herniated disk in the neck and in the lumbar region continues to be a challenging field of medicine. The classical treatment for a ruptured disk continues to be diskectomy, i.e., removal of the disk from between the vertebrae. In this process, all or a portion of the intervertebral disk is removed, leaving a defect which continues to bother the patients throughout the rest of their lives. An additional procedure is to replace the disk space with a bone graft, usually bone chips cut from the patient's iliac crest, bringing about fusion of the vertebrae above and below the disk, eliminating the empty space between the vertebrae.
Theoretically, a diskectomy with fusion is a satisfactory procedure, though not ideal because the replaced bone does not have any of the functions of the cartilage tissue of the disk, i.e. no cushioning effect, and has complications because of several factors. First, the bone plug used to pack the disk space does not conform to the shape of the disk because the disk bulges maximally in the center. The disk space is wider in the middle and narrower at its anterior and posterior ends. Consequently, a bone plug having its maximum width at the center, e.g., one which is shaped to fit the space, cannot be inserted through the narrow mouth of the disk space. For this reason, the various bone plugs which are currently available commercially have only four contact points, i.e. at the front and back of the disk space. Secondly, access to the disk is from one side or the other of the dorsal spine of the adjacent vertebrae, leaving a space that is "off-center" relative to the bodies of the adjacent vertebrae. An implant inserted into that off-center space, therefore, replaces only a portion of the disk and consequently contacts only a portion of the bodies of the adjacent vertebrae such that the stability of the implant is even more problematical than might be apparent from the limited contact resulting from the shape of the intervertebral space in the first place. Another complication is the possibility of infection or other conditions which may require the removal of the implant. Also, if the bone pieces do not fuse, they may eventually extrude out of the disk space, causing pressure on the nerve roots.
Various prosthetic disk plugs, or implants, are disclosed in the art, but all are characterized by limitations of not conforming to the shape of the disk space, lack of stability when inserted off-center, inability to be removed, or other disadvantages. For instance, U.S. Patent No. 4,863,476 describes an elongated body divided longitudinally into two portions having a cam device movable therebetween for increasing the space between the two body portions. However, that device is generally cylindrical in shape such that the only contact points are at the front and back of the disk space, creating increased likelihood of instability and generally rendering that device unsuitable for use after partial 5 diskectomy. The art also discloses intervertebral disk prostheses (e.g., U.S. Patent Nos. 3,867,728, 4,309,777, 4,863,477 and 4,932,969 and French Patent Application No. 8816184) which may have more general contact with the adjacent disks, but which are not intended for use in
10 fusion of the disks. The art also includes spinal joint prostheses such as is described in U.S. Patent No. 4,759,769, which is again not indicated for use when fusion is the preferred surgical intervention.
From this prior art, it is apparent that there has
15 long been a need for a disk plug, or implant, capable of supporting the disk space after a simple diskectomy for fusion of adjacent vertebrae, and the object of the present invention is to provide such an implant.
SUMMARY OF THE INVENTION
20 An intervertebral disk implant is described for implantation into the disk space after surgical removal of all or a portion of a diseased or damaged disk. Implants according to this invention include means for changing the shape of the implant to adapt to the shape of the disk
25 space by expanding the implant to conform to the contour of that space, and are, for that reason, referred to herein as being "middle expandable".
In one embodiment, there is provided an intervertebral disk implant with a cylindrical body comprised of subunits
30 capable of radially outward expansion. In another embodiment, there is provided an implant having a
*
\ substantially rectangular body likewise comprised of subunits capable of radially outward expansion. Both are disk plugs expandable in, the middle portion to provide contact with substantially the entire area of the disk space against the vertebral bodies.
In the method of the present invention, there is provided a method of fusing two adjacent vertebrae after removal of all or a portion of the disk from therebetween which comprises inserting a disk implant into the space from which the disk has been removed, expanding the middle portion of the implant outwardly in a radial direction, injecting cancellous bone chips into the disk space medial to the implant, and applying a physiologically compatible adhesive over the bone chips medial to the implant to close off the opening of the disk space.
BRIEF DESCRIPTION OF THE DRAWINGS In the drawings, Figure 1 is a projected view of one embodiment of the disk implant of the present invention.
Figure 2 is a cross sectional view of the disk implant of Fig. 1 taken along the line 2-2 in Fig. 1.
Figure 3 is a projected view of the central axis of the disk implant of Fig. 1 having the members coiled therearound removed therefrom.
Figure 4 is a projected view of the implant of Fig. 1 after expansion of the middle portion thereof.
Figure 5 is a projected, exploded view of a second embodiment of the disk implant of the present invention. Figure 6 is a projected view of the implant of Fig. 5 showing that implant after expansion thereof.
Figure 7 is a top, plan view of a lumbar vertebra of a human patient having a top, plan view of the implant of
Fig. 6 superimposed thereon to show the spatial relationship of the implant to the adjacent vertebrae after insertion into the disk space.
Figure 8 is a projected view of another embodiment of the implant of the present invention.
Figure 9 is a projected view of the disk implant of Fig. 8 after expansion of the middle portion thereof. Figure 10 is an exploded, projected view of a fourth embodiment of the implant of the present invention.
Figure 10A is a side view of two hinged members comprising the middle portion of the implant of Fig. 10 and removed therefrom.
Figure 11 is a projected view of a fifth embodiment of the disk implant of the present application.
Figure 12 is a cross sectional view of the disk implant of Fig. 11 taken along the line 12-12 in Fig. 11. Figure 13 is a side view of the disk implant of Fig. 11 showing a portion broken away therefrom.
DETAILED DESCRIPTION OF THE INVENTION Figure 1 depicts a cylindrical embodiment of the disk implant of the present invention. The disk implant 20 shown in that figure is comprised of a strong, thin non- porous material. Suitable materials for the disk implant 20 include modified carbon, titanium, steel, metals and/or metal alloys having a memory (see below) , physiologically inert and/or medically compatible polymers such as a urethane or DELRIN® polymer, or any generally rigid, biologically compatible material used for surgical implants. It is also useful to use a material which is compatible with magnetic resonance imaging (MRI) procedures. The disk implant 20 is comprised of a plurality of longitudinally aligned sections, or subunits 22, 24 and 26, and a screw 28 to which each section is mounted (as described below) is turned to cause differential, radially outward expansion of subunits 24 and 26. The subunits 24 and 26 are preferably comprised of a material capable of maintaining spring tension and are mounted to and wound around an elongate longitudinal axis in the form of central rod 25 (see Figs. 2 and 3) integral with screwhead 28. Because of this structure, each of the subunits is conveniently referred to as including a coiled member as identified at reference numeral 32. Each coiled member 32 is mounted to central rod 25 by welding, riveting, or by other manner depending upon the material(s) comprising the sheet 32 and central rod 25 as known in the art. In the preferred embodiment shown in Figures 1-4, the central rod 25 is provided with a flat 23 to provide a stable surface for mounting of the member 32 thereto by, for instance, welding. At the other, free end of each coiled member 32, the coiled member 32 is beveled as at reference numeral 33 so as to provide a smooth, generally round exterior surface on each of the subunits 24 and 26 and to facilitate the sliding of the free end of coiled member 32 along the outside surface thereof as the subunits 24 and 26 are expanded radially outwardly as described below. A Phillips head-type slot 18 is provided in the screwhead 28 for rotation of the rod 25 as described below, and the head 28 is provided with a plurality of teeth 19 for interdigitating with the reciprocal cavities in the lock nut 21 to prevent undesired rotation of central rod 25. The Allen screws 30 are loosened to force lock nut 21 away from the end surface 27 of subunit 22 so that the teeth 19 on the head 28 of central rod 25 are disengaged from the cavities in lock nut 21 to allow rotation of screwhead 28 and rod 25. Alternatively, either or both of rod 25 or lock nut 21 is comprised of a resilient, medically compatible polymer material which allows rotation of the teeth 19 past the cavities in lock nut 21 in one direction but not the other. The expanded shape of a section of the disk implant 20 is shown in Figure 2. Turning screwhead 28 and central rod 25 using the slot 18 expands the sections 24 and 26, which remain expanded due to the interaction of the teeth 19 and the cavities in lock nut 21 and the compression of the implant 20 between the bodies of the vertebrae above and below the implant 20 once inserted into the disk space. In other words, engagement of the free end of coiled member 32 by the adjacent vertebrae prevents the slipping of the free end of the coiled member 32 around the outside circumference of implant 20 such that members 32 do not "re-wind" after being expanded.
As shown in Figure 3, central rod 25 is provided with a portion 29 approximately mid-way between the ends thereof having a larger diameter than the rest of the central rod 25. By use of the central rod with sections of different diameters and/or thicknesses of the cylindrically wound member 32, the subunits 24 and 26 are differentially expanded. Turning screw 28 allows for maximal expansion of the subunit 26 and moderate expansion of the subunit 24 because the member 32 comprising subunit 26 is mounted to the rod 25 on the portion 29 of larger diameter while each of the members 32 comprising subunits 22 and 24 is mounted to central rod 25 between the portion 29 and the subunits 22. Turning the central rod 25 uncoils the members 32 because each member 32 is attached to the central rod 25. Figure 4 illustrates the cylindrical disk implant 20 in its radially expanded form. Once expanded, the implant cannot be removed from the disk space except by turning the alien screws 30 to either back out or remove lock nut 21, thereby allowing rotation of rod 25. Referring now to Figures 5 and 6, an alternative embodiment of the implant 20 is shown at reference numeral 56. Implant 56 is comprised of a single piece of metal, such as a titanium alloy, or medical grade polymeric plastic, such as DELRIN®, which is resilient and has a memory for the shape in which it is molded, shown in Fig. 6. Implant 56 is molded in the same generally elongate, cylindrical shape as the implant 20 shown in Figs. 1-4, but is molded in a shape in which the middle portion 58 thereof is normally expanded radially outwardly from the central axis of the cylinder. An elongate screw 60 is provided having two sets of threads 62 and 66 thereon, the former for engaging the threads 68 formed in the bore 70 extending longitudinally through implant 56, the latter for engaging a similarly formed set of threads located in the bore 70 at the other end of implant 56 and therefore not visible in Figures 5 and 6. A slot 72 is formed in the head 74 of screw 60 for turning screw 60 to move the opposite ends 76a and 76b of implant 56 away from each other, thereby extending implant 56 and decreasing the radially outward expansion of the middle 58 thereof as shown in Fig. 5 for insertion into the disk space. Longitudinal slots 75 are molded into implant 56 to form ribs 77 which flex to allow the extension and outward expansion of implant 56 in this manner. As noted above, the instability of prior implants once inserted into the disk space is problematical, and Fig. 7, showing the implant 56 in place relative to the body 78 of an adjacent lumbar vertebra 80 illustrates how the apparatus of the present invention overcomes this limitation of prior implants. The implant 56 is inserted into the disk space in an anterior-posterior (A-P) orientation, the dorsal spine 82 of vertebra 80 being pointed posterially. As clearly shown in Fig. 7, when so positioned, implant 56 occupies only a portion of the surface area of the vertebral body 78, the remainder of the area being occupied by that portion of the intervertebral disk (not shown) which is not removed during the diskectomy procedure (or, in a fusion procedure, this area is packed with cancellous bone chips) . Access to that area is from the posterior aspect of the disk medial to the implant. In addition, the periphery 88 of vertebral body 78 is, as described above, thicker than the central portion 90 of body 78, further limiting access and creating an uneven surface on which the body 78 bears on the implant. However, because of the expansion of only the middle 58 of implant 56, the implant 56 is stable in the A-P orientation shown. Once implanted, the screw 60 is backed out of the bore 70 in implant 56 and implant 56 assumes the shape shown in Figs. 6 and 7. Figure 8 depicts a rectangular disk implant 31 constructed according to the present invention. Turning Phillips head 39 of screw 42 encapsulated in a sheath 44 (best shown in Fig. 9) formed in the hinged members 34 and 36 forming intermediate subunits in the same manner as the subunits, or sections, 24 and 26 of implant 20 causes the radially outward expansion of superior hinged members 34 superiorly and inferior hinged members 36 inferiorly. Although shown in Figures 8 and 9 with two of the hinged members 34 and 36, it will be understood by those skilled in the art who have the benefit of this disclosure that the plug, or implant, 31 may be provided with four, eight, or even more of the hinged members 34 and 36 as shown at reference numerals 92 and 94 in Figure 10 and numeral 41 in Figures 11-13. The expanded shape of the rectangular disk plug 31 is illustrated in Figure 9. Hinged members 34 and 36 are secured to an end cap or subunit 33 by hinge 38 and to each other by hinge 46. Upon rotation of screw 42 using a conventional screwdriver and the Phillips head slot 39, the end caps 33 are drawn closer together by movement along the threads of screw 42. To insure that the members 34 and 36 expand radially outwardly from screw 42, the ends 48 of each respective member 34 and 36 abutting the end caps 33 are angled so as to create a force vector outwardly away from screw 42 when end cap 33 exerts pressure on the surface 48, the hinge 38 being mounted in the acute angle formed by surface 48 and end cap 33.
In one embodiment (best shown in Figures 11-13 and discussed below) , the tendency of this force vector to cause the members 34 and 36 to expand is increased by angling the face 50 of one member 34 or 36 in . the same direction as the angle in the surface 48. The surface 52 of the opposed member 34 and 36 is similarly angled, but with a bearing surface 54 formed therein that is angled in the same direction as the angle in surface 48 and face 50 so that the face 50 rides upwardly onto bearing surface 54 to translate the opposed, end-to-end force vectors applied to end caps 33 by rotation of screw 42 into a force vector having a radially outward (from screw 42) component. By referring to Figures 11-13, it can be seen that the radially outward expansion of the middle portion of implant 31 caused by rotation of the screw 42 effectively simulates the opening of two opposed umbrellas, and the particular embodiment shown in those figures may be conveniently referred to as having a "double umbrella" configuration. A threaded lock nut 40 is inserted over Phillips screw head 39 (see Figure 8) . Lock nut 40 prevents the members 34 and 36 from moving once expanded. Removing lock nut 40 provides access to screw head 39 to allow members 34 and 36 to return to the position shown in Figure 8. The above-referenced, double-umbrella configuration of the implant of the present invention is illustrated at reference numeral 88 in Figure 10. In this embodiment, the hinged members 92 and 94 are mounted on pivot pins 96 to the first and second end members 90 and 98, respectively, as well as to each other, most of the pins 96 and all but two sets of the hinged members 92 and 94 being omitted from the figure for purposes of clarity. The pivot pins 96 which mount members 92 and 94 to the ends 90 and 98 are received within the bores 100 and 102 formed in each end member 90 and 98, the bores 100 and 102 being numbered separately to draw attention to their arrangement on the end members 90 and 98. The ears 104 on hinged members 92' and 94' are longer than the ears 106 on hinged members 92* ' and 94' ' and the bores 100# for receiving the pivot pin 96 are located closer to the end surface 108 of end member 90 (and the corresponding end surface of end member 98 at the opposite end of implant 88) than the bores 102. By this arrangement, the strength of the implant 88 is significantly increased. Expansion of the middle portion of implant 88 is accomplished by turning the screw 112 using the hex head 114 formed at one end thereof, the other end of screw 112 being received by the threads 115 formed in the second end member 98. To increase the tendency of the hinged members 92 and 94 to expand in the radially outward direction, the holes in the hinged members 92 and 94 in which pivot pins 96 reside are offset along the longitudinal axis of implant 88. The offset holes are better shown in Figure 10A in which one pair of the members 92 and 94 is shown in side view removed from implant 88. The direction of expansion is shown by the arrow 95 in Figure 10A and, as can be seen, the center holes 97 are offset outwardly (e.g., in the direction of arrow 95) relative to the holes 99 at the ends of hinged members 92 and 94 (e.g., in the ears 106). A lock nut 116 having threads 118 formed in the outside surface thereof is received by the threads 120 formed in the bore 122 in end member 90 through which the screw 112 is received for preventing undesired rotation of screw 112. Lock nut 116 is provided with a hex slot 124 to facilitate insertion and/or removal and hex slot 124 extends all the way through lock nut 116 and is of large enough size that a hex key can be inserted through slot 124 and into hex head 114 for turning screw 112 without adjustment of lock nut 116. Another embodiment of the double-umbrella configuration of the implant of the present invention is shown at reference numeral 41 in Figures 11-13. As is the case with the implant 88 shown in Figure 10, the implant 41 is generally cylindrical in shape, yet utilizes the hinged member 34 and 36 construction of implant 31 shown in Figures 8 and 9. Figure 12 shows a projected view of the disk implant 41 shown in Figure 11 having the members 34 and 36 cut in section. This view shows how the hinged members 34 and 36 fit together in the unexpanded position due to their beveled sides 64, giving the implant 41 its generally cylindrical shape. The sides 110 of the hinged members 92 and 94 of implant 88 are similarly beveled (Figure 10) .
All of the disk implants of the present invention are expandable in the middle portion, i.e., the portion intermediate the ends, to contact substantially the entire anterior-posterior dimension of the disk space against the vertebral bodies as described above in connection with the description of Figure 7. If a complete intervertebral fusion is being performed, the plug is used in conjunction with intervertebral cancellous bone packing. Because of the support provided by the plug, until fusion is established, the cancellous bone pieces have a better chance of fusion due to the presence of the implant, and the bone pieces and the disk implant have a better chance of staying in the intervertebral disk space. Alternatively, the plug is used to maintain the spacing between vertebrae and can be used in conjunction with intertransverse posterior lateral fusion. In short, the implant acts as a physiological support for the rest of the patient's life or until a bone fusion is established.
The disk implant of the present invention may have additional indications, e.g. short segment scoliosis, where the curvature of the spine can be corrected by distracting the vertebral bodies on the inside of the curvature. By expanding the middle portion of the plug inside the disk space, the vertebral bodies are distracted, thereby helping straighten the spinal column.
If no bone graft is planned, diskectomy can be made minimally through one side exposure so that when the disk plug is inserted and expanded, it will occupy the empty space. Because there is no further movement at this disk space, the chance of recurrent disk herniation is minimized. Also, the likelihood of recurrent disk herniation due to opening and closing of the space on the side of the diskectomy is reduced because the disk plug closes this mouth. Consequently, in addition to the advantages of a one sided, simple diskectomy, the risk of recurrent disk herniation can be reduced. The cylindrical 20, 41, 56, and 88 and rectangular 31 implants are inserted after a simple diskectomy. Ordinarily, the size of the disk implant is approximately 2.5 to 3.5 centimeters in length and 1.0 to 1.5 centimeters in height and width. The same plug in smaller dimensions is used in thoracic and cervical levels where indicated.
By reference to the figures, it can be seen that both the rectangular and the cylindrical implants have the common feature of being expandable in the middle without changing the diameter of the dimensions of the two ends. Consequently, surgery is performed as in simple diskectomy, and the disk is exposed through a small laminoto y. The disk material is removed and any nerve root compression is corrected. The posterior longitudinal ligament and disk cartilage are removed until the vertebral surfaces are exposed above and below the disk space. The shape of the disk space determines whether the disk plug used is cylindrical or rectangular. The disk plug is then inserted and hammered into place so that the anterior end of the disk plug almost touches the anterior longitudinal ligament. Subsequently, using a Phillips screwdriver, the posterior screw end is turned. This implant method also gives good distraction to the vertebral bodies. In the case of simple disk problems, no further treatment may be required. When used in interbody fusion, cancellous bone chips are made into very fine particles and pumped into the disk space medial to the disk plug and packed into the space. The posterior longitudinal ligament is intact to the opposite side and to the center of the disk space. These cancellous bone chips are held tightly in place. Since the mouth of the disk space is closed with the disk plug, the risk of the cancellous bone chips coming out is minimized. Also, the disk plug prevents the opening and closing of the disk space, thus preventing the bone chips coming out. If necessary, a small amount of a physiologically compatible adhesive of a type known in the art is applied over the cancellous bone chips just medial to the disk plug to close off the remaining portion of the opening of the disk space. The patient should be able to ambulate soon after the surgery because of the stability given by the disk plug. Before narrowing of the disk space occurs, the cancellous bone chips will have started the fusion process.
If a posterior lateral intertransverse fusion is desired, this procedure is also done in conjunction with the middle expandable disk plug. The disk plug is applied as explained above and the posterior lateral fusion performed. Since the disk plug provides stability to the spine until the posterior lateral fusion is solid, the patient can ambulate soon after the surgery. This procedure also prevents the disk space narrowing, which is a common problem with posterior lateral fusion.

Claims

WHAT IS CLAIMED IS:
1. An implant for disposition in the space between two vertebrae of a patient after removal of a portion of the disk therefrom comprising: an elongate, threaded rod; first and second end caps having holes there¬ through for receiving said rod, the hole in said second end cap being threaded for engaging the threads on said rod to move said second end cap along said rod relative to said first end cap when said rod is rotated; and an intermediate portion mounted between said first and second end caps, whereby rotation of said rod causes radially outward expansion of said intermediate portion to conform the shape of the expanded implant to the shape of the anatomical region of the disk space.
2. An implant of claim 1, additionally comprising a lock nut for engaging said rod to prevent the rotation of said rod.
3. An implant of claim 1, wherein said intermediate portion comprises a plurality of members hingedly mounted to said end caps.
4. An implant of claim 3, wherein rotation of said rod causes said second end cap to move along said rod to move said second end cap toward said first end cap, thereby forcing said intermediate portion radially outwardly.
5. An implant of claim 3, wherein the edges of said hinged members are beveled.
6. An implant of claim 3, wherein the hinges between said hinged members are offset so as to cause said hinged members to expand radially outwardly when said rod is rotated.
7. An implant of claim 3, wherein a sheath is formed in said hinged members to allow said hinged members to close around said rod before said hinged members are expanded so as to minimize the thickness of the implant.
8. An implant of claim 1 wherein said intermediate portion comprises a plurality of spring-tensioned members spaced along the length of and wound around said rod and having one end affixed thereto.
9. An implant of claim 8 wherein said rod is provided with a plurality of different diameters spaced along the length thereof and having the end of one of said spring-tensioned members affixed to each section thereof.
10. A method of maintaining the space between two adjacent vertebrae of a patient after removal of the disk from therebetween comprising the steps of: inserting an elongate implant into the space between two vertebrae after removal of the disk therefrom, the implant having a length which approximates the anterior-posterior dimension of the body of the vertebrae and a vertical dimension small enough to allow the insertion of the implant; expanding the implant radially outwardly in the portion intermediate the ends of the implant to conform the shape of the implant to the shape of the anatomical region of the disk space into which the implant is inserted; and preventing the reversal of the outward radial expansion of the intermediate portion of the implant.
11. A method of claim 10 further comprising injecting cancellous bone chips into said disk space medial to the disk plug.
12. A method for fusing two adjacent vertebrae after removal of a portion of the disk from therebetween comprising the steps of: inserting an elongate implant through an opening into a space between two adjacent vertebrae of a patient after removal of the disk from between the vertebrae, the implant having a length which approximates the anterior-posterior dimension of the body of the vertebrae and a vertical dimension small enough to allow insertion of the implant; expanding the middle portion of the implant outwardly in a radial direction to conform the shape of the implant to the shape of the space from which the disk has been removed; injecting cancellous bone chips into the space between the vertebrae medial to the implant; and applying a physiologically compatible adhesive over the cancellous bone chips medial to the disk implant to close off the opening into the space from which the disk has been removed.
PCT/US1992/001397 1991-02-22 1992-02-21 Middle expandable intervertebral disk implant and method WO1992014423A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE69209494T DE69209494T2 (en) 1991-02-22 1992-02-21 IMPLANT FROM AN EXPANDABLE INTERMEDIATE DISC
CA002104391A CA2104391C (en) 1991-02-22 1992-02-21 Middle expandable intervertebral disk implant and method
US08/107,750 US5390683A (en) 1991-02-22 1992-02-21 Spinal implantation methods utilizing a middle expandable implant
JP50735292A JP3390431B2 (en) 1991-02-22 1992-02-21 Centrally expandable disc implant and method
EP92907757A EP0571555B1 (en) 1991-02-22 1992-02-21 Middle expandable intervertebral disk implant

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US659,758 1991-02-22
US07/659,758 US5171278A (en) 1991-02-22 1991-02-22 Middle expandable intervertebral disk implants
US78675891A 1991-11-01 1991-11-01
US786,758 1991-11-01

Publications (1)

Publication Number Publication Date
WO1992014423A1 true WO1992014423A1 (en) 1992-09-03

Family

ID=27097891

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1992/001397 WO1992014423A1 (en) 1991-02-22 1992-02-21 Middle expandable intervertebral disk implant and method

Country Status (7)

Country Link
US (1) US5693100A (en)
EP (1) EP0571555B1 (en)
JP (1) JP3390431B2 (en)
AU (1) AU1454192A (en)
CA (1) CA2104391C (en)
DE (1) DE69209494T2 (en)
WO (1) WO1992014423A1 (en)

Cited By (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258031A (en) * 1992-01-06 1993-11-02 Danek Medical Intervertebral disk arthroplasty
DE4323956C1 (en) * 1993-07-19 1994-10-27 Eska Medical Gmbh & Co Fusion dowel for vertebrae
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
WO1995008306A1 (en) * 1993-09-21 1995-03-30 Synthes Ag, Chur Implant for the intervertebral space
DE4416605C1 (en) * 1994-05-11 1995-06-08 Aesculap Ag Inter-vertebral implant
US5425773A (en) * 1992-01-06 1995-06-20 Danek Medical, Inc. Intervertebral disk arthroplasty device
FR2715293A1 (en) * 1994-01-26 1995-07-28 Biomat Vertebral interbody fusion cage.
FR2717068A1 (en) * 1994-03-14 1995-09-15 Biomat Intersomatic cage insertable between two vertebral bodies
WO1995025485A1 (en) * 1994-03-23 1995-09-28 Schnorrenberg Chirurgiemechanik Gmbh Positioning and support device for the spinal column
WO1995025487A1 (en) * 1994-03-18 1995-09-28 Madhavan Pisharodi Middle expanded, removable intervertebral disk stabilizer and method of lumbar intervertebral disk stabilization
FR2718955A1 (en) * 1994-04-25 1995-10-27 Soprane Sa Intersomatic cage for fusion of lumbar vertebrae
FR2719763A1 (en) * 1994-05-11 1995-11-17 Jean Taylor Vertebral implant.
FR2722679A1 (en) * 1994-07-25 1996-01-26 Daniel Felman Expansible arthrodesis implant for insertion between vertebrae
WO1996027348A1 (en) * 1995-03-08 1996-09-12 Synthes Ag, Chur Intervertebral implant
WO1996040016A2 (en) * 1994-03-18 1996-12-19 Madhavan Pisharodi Intervertebral disk stabilizer and instrument for reduction of spondylolisthesis
US5658336A (en) * 1994-03-18 1997-08-19 Pisharodi; Madhavan Rotating, locking, middle-expanded intervertebral disk stabilizer
WO1998017207A1 (en) * 1996-10-21 1998-04-30 Synthes Ag Chur Surgical prosthetic device
FR2760355A1 (en) * 1997-03-07 1998-09-11 Serge Schrayer Intersomatic cage, e.g. for fusion of vertebrae or joint bones
WO1998038918A1 (en) 1997-03-07 1998-09-11 Mordechay Beyar Systems for percutaneous bone and spinal stabilization, fixation and repair
EP0853932A3 (en) * 1997-01-21 1998-10-07 Spinal Innovations Fusion implant
WO1998055051A1 (en) * 1995-12-05 1998-12-10 Metagen, Llc Modular prosthesis
US5893890A (en) * 1994-03-18 1999-04-13 Perumala Corporation Rotating, locking intervertebral disk stabilizer and applicator
WO1999029271A1 (en) * 1997-12-10 1999-06-17 Sdgi Holdings, Inc. Osteogenic fusion device
DE19816832C1 (en) * 1998-04-16 2000-01-20 Aesculap Ag & Co Kg Surgical vertebral implant
US6019792A (en) * 1998-04-23 2000-02-01 Cauthen Research Group, Inc. Articulating spinal implant
FR2783702A1 (en) * 1998-09-29 2000-03-31 Maurice Bertholet Self-locking prosthesis for bone insert has heat activated anchor flanges formed on central core
WO2000025706A1 (en) * 1998-10-29 2000-05-11 Sdgi Holdings, Inc. Expandable intervertebral spacers
US6077265A (en) * 1995-04-21 2000-06-20 Werding; Gerd Nail for fixing the position and shape of broken long bones
US6080155A (en) * 1988-06-13 2000-06-27 Michelson; Gary Karlin Method of inserting and preloading spinal implants
WO2000045752A1 (en) * 1999-02-04 2000-08-10 Aesculap Ag & Co. Kg Rehabitable linking screw for arthrodesis of a bone joint for stabilising two vertebrae
US6113638A (en) * 1999-02-26 2000-09-05 Williams; Lytton A. Method and apparatus for intervertebral implant anchorage
US6179874B1 (en) 1998-04-23 2001-01-30 Cauthen Research Group, Inc. Articulating spinal implant
US6241770B1 (en) 1999-03-05 2001-06-05 Gary K. Michelson Interbody spinal fusion implant having an anatomically conformed trailing end
US6264655B1 (en) 1995-06-07 2001-07-24 Madhavan Pisharodi Cervical disk and spinal stabilizer
US6350283B1 (en) 2000-04-19 2002-02-26 Gary K. Michelson Bone hemi-lumbar interbody spinal implant having an asymmetrical leading end and method of installation thereof
US6375655B1 (en) 1995-03-27 2002-04-23 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
US6423095B1 (en) 1995-10-16 2002-07-23 Sdgi Holdings, Inc. Intervertebral spacers
US6436140B1 (en) * 1998-08-28 2002-08-20 Sofamor S.N.C. Expandable interbody fusion cage and method for insertion
US6436098B1 (en) 1993-06-10 2002-08-20 Sofamor Danek Holdings, Inc. Method for inserting spinal implants and for securing a guard to the spine
US6648916B1 (en) 1997-12-10 2003-11-18 Sdgi Holdings, Inc. Osteogenic fusion device
US6679915B1 (en) 1998-04-23 2004-01-20 Sdgi Holdings, Inc. Articulating spinal implant
US6761738B1 (en) 2000-09-19 2004-07-13 Sdgi Holdings, Inc. Reinforced molded implant formed of cortical bone
US6780192B2 (en) 2000-10-24 2004-08-24 Sdgi Holdings, Inc. Osteogenic packing device and method
DE19720241B4 (en) * 1997-05-15 2005-12-29 Eska Implants Gmbh & Co. Interbody fusion implant
EP1402853A3 (en) * 2002-09-27 2006-03-22 Depuy Products, Inc. Concave resurfacing glenoid prosthesis
US7018415B1 (en) 2002-09-23 2006-03-28 Sdgi Holdings, Inc. Expandable spinal fusion device and methods of promoting spinal fusion
US7097648B1 (en) 1999-01-27 2006-08-29 Disc-O-Tech Medical Technologies Ltd. Expandable element delivery system
WO2006118867A1 (en) * 2005-04-29 2006-11-09 Warsaw Orthopedic, Inc. Expandable intervertebral implant and associated instrumentation
US7156875B2 (en) 2000-04-19 2007-01-02 Warsaw Orthopedic, Inc. Arcuate artificial hemi-lumbar interbody spinal fusion implant having an asymmetrical leading end
US7276081B1 (en) 1995-10-16 2007-10-02 Warsaw Orthopedic, Inc. Bone grafts
US7285135B2 (en) 1997-12-10 2007-10-23 Warsaw Orthopedic, Inc. Osteogenic fusion device
US7361192B2 (en) 2005-04-22 2008-04-22 Doty Keith L Spinal disc prosthesis and methods of use
FR2937245A1 (en) * 2008-10-22 2010-04-23 Marc Palmieri Orthopedic implant e.g. glenoid implant support base, press-fit type fixation device for e.g. spongy bone of scapula, has plot that is expandable under force exerted on area of plot after implementation of support part of implant
US7717959B2 (en) 2002-03-30 2010-05-18 Lytton William Intervertebral device and method of use
US7799080B2 (en) 2005-04-22 2010-09-21 Doty Keith L Spinal disc prosthesis and methods of use
US7935149B2 (en) 2001-04-02 2011-05-03 Warsaw Orthopedic, Inc. Spinal fusion implant with bone screws
WO2011028396A3 (en) * 2009-08-26 2011-06-30 Synthes Usa, Llc Stabilizing bone fixation element
US7981156B2 (en) 1995-10-16 2011-07-19 Warsaw Orthopedic, Inc. Bone grafts
EP2408382A1 (en) * 2009-03-13 2012-01-25 The University of Toledo Minimally invasive collapsible cage
US8137403B2 (en) 2001-04-02 2012-03-20 Warsaw Orthopedic, Inc. Hemi-interbody spinal fusion implants manufactured from a major long bone ring
US8343220B2 (en) 1999-05-05 2013-01-01 Warsaw Orthopedic, Inc. Nested interbody spinal fusion implants
US8435295B2 (en) 2005-09-26 2013-05-07 Infinity Orthopaedics Company System and method for intervertebral implant delivery and removal
US8608804B2 (en) 2004-03-29 2013-12-17 Nuvasive, Inc. Systems and methods for spinal fusion
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US8845733B2 (en) 2010-06-24 2014-09-30 DePuy Synthes Products, LLC Lateral spondylolisthesis reduction cage
US8870960B2 (en) 2005-07-28 2014-10-28 Nuvasive, Inc. Total disc replacement system and related methods
US8920500B1 (en) 2009-04-16 2014-12-30 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US8950929B2 (en) 2006-10-19 2015-02-10 DePuy Synthes Products, LLC Fluid delivery system
US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US8992541B2 (en) 2003-03-14 2015-03-31 DePuy Synthes Products, LLC Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US9050112B2 (en) 2011-08-23 2015-06-09 Flexmedex, LLC Tissue removal device and method
US9149286B1 (en) 2010-11-12 2015-10-06 Flexmedex, LLC Guidance tool and method for use
US9168152B2 (en) 2008-02-29 2015-10-27 Nuvasive, Inc. Implants and methods for spinal fusion
US9186261B2 (en) 2007-03-07 2015-11-17 Nuvasive, Inc. System and methods for spinal fusion
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9226764B2 (en) 2012-03-06 2016-01-05 DePuy Synthes Products, Inc. Conformable soft tissue removal instruments
US9259329B2 (en) 2004-09-21 2016-02-16 Stout Medical Group, L.P. Expandable support device and method of use
US9259696B2 (en) 2005-11-22 2016-02-16 DePuy Synthes Products, Inc. Mixing apparatus having central and planetary mixing elements
USD754346S1 (en) 2009-03-02 2016-04-19 Nuvasive, Inc. Spinal fusion implant
US9351845B1 (en) 2009-04-16 2016-05-31 Nuvasive, Inc. Method and apparatus for performing spine surgery
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9387090B2 (en) 2009-03-12 2016-07-12 Nuvasive, Inc. Vertebral body replacement
RU2592606C1 (en) * 2015-04-28 2016-07-27 федеральное государственное автономное образовательное учреждение высшего образования "Самарский государственный аэрокосмический университет имени академика С.П. Королева (национальный исследовательский университет)" (СГАУ) Vertebral implant
US9445918B1 (en) 2012-10-22 2016-09-20 Nuvasive, Inc. Expandable spinal fusion implants and related instruments and methods
US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US9687357B2 (en) 2009-03-12 2017-06-27 Nuvasive, Inc. Vertebral body replacement
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
US9770339B2 (en) 2005-07-14 2017-09-26 Stout Medical Group, L.P. Expandable support device and method of use
US9839460B2 (en) 2003-03-31 2017-12-12 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US9931224B2 (en) 2009-11-05 2018-04-03 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US10022245B2 (en) 2012-12-17 2018-07-17 DePuy Synthes Products, Inc. Polyaxial articulating instrument
US10285820B2 (en) 2008-11-12 2019-05-14 Stout Medical Group, L.P. Fixation device and method
USRE47427E1 (en) 1999-01-27 2019-06-11 Medtronic Holding Company Sárl Expandable intervertebral spacer
US10758289B2 (en) 2006-05-01 2020-09-01 Stout Medical Group, L.P. Expandable support device and method of use
US10856997B2 (en) 2018-02-22 2020-12-08 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US10940014B2 (en) 2008-11-12 2021-03-09 Stout Medical Group, L.P. Fixation device and method
US10966843B2 (en) 2017-07-18 2021-04-06 DePuy Synthes Products, Inc. Implant inserters and related methods
US10973650B2 (en) 2015-12-30 2021-04-13 Nuvasive, Inc. Lordotic expandable fusion implant
US11020239B2 (en) 2018-02-22 2021-06-01 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US11045331B2 (en) 2017-08-14 2021-06-29 DePuy Synthes Products, Inc. Intervertebral implant inserters and related methods
US11234833B2 (en) 2015-05-12 2022-02-01 Nuvasive, Inc. Expandable lordosis intervertebral implants
US11273047B2 (en) 2017-12-18 2022-03-15 Nuvasive, Inc. Expandable implant device
US11285014B1 (en) 2020-11-05 2022-03-29 Warsaw Orthopedic, Inc. Expandable inter-body device, system, and method
US11291554B1 (en) 2021-05-03 2022-04-05 Medtronic, Inc. Unibody dual expanding interbody implant
US11344424B2 (en) 2017-06-14 2022-05-31 Medos International Sarl Expandable intervertebral implant and related methods
US11369490B2 (en) 2011-03-22 2022-06-28 DePuy Synthes Products, Inc. Universal trial for lateral cages
US11376134B1 (en) 2020-11-05 2022-07-05 Warsaw Orthopedic, Inc. Dual expanding spinal implant, system, and method of use
US11395743B1 (en) 2021-05-04 2022-07-26 Warsaw Orthopedic, Inc. Externally driven expandable interbody and related methods
US11426290B2 (en) 2015-03-06 2022-08-30 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US11432942B2 (en) 2006-12-07 2022-09-06 DePuy Synthes Products, Inc. Intervertebral implant
US11446155B2 (en) 2017-05-08 2022-09-20 Medos International Sarl Expandable cage
US11446156B2 (en) 2018-10-25 2022-09-20 Medos International Sarl Expandable intervertebral implant, inserter instrument, and related methods
US11452607B2 (en) 2010-10-11 2022-09-27 DePuy Synthes Products, Inc. Expandable interspinous process spacer implant
US11497619B2 (en) 2013-03-07 2022-11-15 DePuy Synthes Products, Inc. Intervertebral implant
US11510788B2 (en) 2016-06-28 2022-11-29 Eit Emerging Implant Technologies Gmbh Expandable, angularly adjustable intervertebral cages
US11517443B2 (en) 2020-11-05 2022-12-06 Warsaw Orthopedic, Inc. Dual wedge expandable implant, system and method of use
US11564724B2 (en) 2020-11-05 2023-01-31 Warsaw Orthopedic, Inc. Expandable inter-body device, system and method
US11596523B2 (en) 2016-06-28 2023-03-07 Eit Emerging Implant Technologies Gmbh Expandable and angularly adjustable articulating intervertebral cages
US11602438B2 (en) 2008-04-05 2023-03-14 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11607321B2 (en) 2009-12-10 2023-03-21 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
US11612499B2 (en) 2021-06-24 2023-03-28 Warsaw Orthopedic, Inc. Expandable interbody implant
US11612491B2 (en) 2009-03-30 2023-03-28 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US11622868B2 (en) 2007-06-26 2023-04-11 DePuy Synthes Products, Inc. Highly lordosed fusion cage
US11638653B2 (en) 2020-11-05 2023-05-02 Warsaw Orthopedic, Inc. Surgery instruments with a movable handle
US11654033B2 (en) 2010-06-29 2023-05-23 DePuy Synthes Products, Inc. Distractible intervertebral implant
US11679000B2 (en) 2013-05-22 2023-06-20 Nuvasive, Inc. Expandable fusion implant and related methods
US11730608B2 (en) 2021-07-13 2023-08-22 Warsaw Orthopedic, Inc. Monoblock expandable interbody implant
US11737881B2 (en) 2008-01-17 2023-08-29 DePuy Synthes Products, Inc. Expandable intervertebral implant and associated method of manufacturing the same
US11752009B2 (en) 2021-04-06 2023-09-12 Medos International Sarl Expandable intervertebral fusion cage
US11806245B2 (en) 2020-03-06 2023-11-07 Eit Emerging Implant Technologies Gmbh Expandable intervertebral implant
US11833059B2 (en) 2020-11-05 2023-12-05 Warsaw Orthopedic, Inc. Expandable inter-body device, expandable plate system, and associated methods
US11850160B2 (en) 2021-03-26 2023-12-26 Medos International Sarl Expandable lordotic intervertebral fusion cage
US11850163B2 (en) 2022-02-01 2023-12-26 Warsaw Orthopedic, Inc. Interbody implant with adjusting shims
US11872139B2 (en) 2010-06-24 2024-01-16 DePuy Synthes Products, Inc. Enhanced cage insertion assembly

Families Citing this family (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998017188A1 (en) 1996-10-24 1998-04-30 Spinal Concepts, Inc. Method and apparatus for spinal fixation
US6416515B1 (en) 1996-10-24 2002-07-09 Spinal Concepts, Inc. Spinal fixation system
US6068630A (en) 1997-01-02 2000-05-30 St. Francis Medical Technologies, Inc. Spine distraction implant
US20080039859A1 (en) 1997-01-02 2008-02-14 Zucherman James F Spine distraction implant and method
US7201751B2 (en) 1997-01-02 2007-04-10 St. Francis Medical Technologies, Inc. Supplemental spine fixation device
US20080086212A1 (en) 1997-01-02 2008-04-10 St. Francis Medical Technologies, Inc. Spine distraction implant
US7306628B2 (en) 2002-10-29 2007-12-11 St. Francis Medical Technologies Interspinous process apparatus and method with a selectably expandable spacer
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US6045579A (en) 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
US5928243A (en) 1997-07-16 1999-07-27 Spinal Concepts, Inc. Pedicle probe and depth gage
US6030389A (en) 1997-08-04 2000-02-29 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
US6454769B2 (en) 1997-08-04 2002-09-24 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
US5964769A (en) 1997-08-26 1999-10-12 Spinal Concepts, Inc. Surgical cable system and method
US6053921A (en) 1997-08-26 2000-04-25 Spinal Concepts, Inc. Surgical cable system and method
WO1999029246A1 (en) * 1997-12-08 1999-06-17 Kyphon Inc. Systems and methods using expandable bodies to push apart cortical bone surfaces
BR9805340B1 (en) * 1998-12-14 2009-01-13 variable expansion insert for spinal stabilization.
US6325827B1 (en) 1999-02-01 2001-12-04 Blacksheep Technologies, Inc. Intervertebral implant
US6557226B1 (en) 1999-04-23 2003-05-06 Michael E. Landry Apparatus for manufacturing a bone dowel
US6214050B1 (en) 1999-05-11 2001-04-10 Donald R. Huene Expandable implant for inter-bone stabilization and adapted to extrude osteogenic material, and a method of stabilizing bones while extruding osteogenic material
US6520991B2 (en) 1999-05-11 2003-02-18 Donald R. Huene Expandable implant for inter-vertebral stabilization, and a method of stabilizing vertebrae
US6419705B1 (en) 1999-06-23 2002-07-16 Sulzer Spine-Tech Inc. Expandable fusion device and method
US7201776B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements with endplates
WO2001015639A1 (en) 1999-09-01 2001-03-08 Sharkey Hugh R Intervertebral spacer implant
US6866682B1 (en) 1999-09-02 2005-03-15 Stryker Spine Distractable corpectomy device
US7201774B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements incorporating reinforced wall sections
US20040172019A1 (en) * 1999-10-08 2004-09-02 Ferree Bret A. Reinforcers for artificial disc replacement methods and apparatus
US7060100B2 (en) * 1999-10-08 2006-06-13 Ferree Bret A Artificial disc and joint replacements with modular cushioning components
US6494883B1 (en) * 2000-05-26 2002-12-17 Bret A. Ferree Bone reinforcers
US6331179B1 (en) 2000-01-06 2001-12-18 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
US6447512B1 (en) 2000-01-06 2002-09-10 Spinal Concepts, Inc. Instrument and method for implanting an interbody fusion device
US6716247B2 (en) 2000-02-04 2004-04-06 Gary K. Michelson Expandable push-in interbody spinal fusion implant
US6500205B1 (en) 2000-04-19 2002-12-31 Gary K. Michelson Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion
EP1645248B8 (en) * 2000-02-04 2010-06-16 Warsaw Orthopedic, Inc. Expandable interbody spinal fusion implant having pivotally attached blocker
US6814756B1 (en) * 2000-02-04 2004-11-09 Gary K. Michelson Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion
US6709458B2 (en) 2000-02-04 2004-03-23 Gary Karlin Michelson Expandable push-in arcuate interbody spinal fusion implant with tapered configuration during insertion
US6821298B1 (en) * 2000-04-18 2004-11-23 Roger P. Jackson Anterior expandable spinal fusion cage system
WO2001091686A1 (en) 2000-05-30 2001-12-06 Lin Paul S Implant for placement between cervical vertebrae
US6808537B2 (en) * 2000-07-07 2004-10-26 Gary Karlin Michelson Expandable implant with interlocking walls
EP1309280A2 (en) 2000-08-11 2003-05-14 SDGI Holdings, Inc. Surgical instrumentation and method for treatment of the spine
US7195643B2 (en) * 2003-08-29 2007-03-27 Jackson Roger P Convex spinal fusion interbody spacer
US8535378B2 (en) * 2004-05-10 2013-09-17 Roger P. Jackson Vertebral interbody spacer
US6824565B2 (en) 2000-09-08 2004-11-30 Nabil L. Muhanna System and methods for inserting a vertebral spacer
US8628575B2 (en) 2000-08-29 2014-01-14 Nabil L. Muhanna Vertebral body replacement and method of use
US7204851B2 (en) 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US7503936B2 (en) 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
CA2549687A1 (en) 2000-08-30 2002-03-07 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US20020026244A1 (en) 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US20050154463A1 (en) * 2000-08-30 2005-07-14 Trieu Hal H. Spinal nucleus replacement implants and methods
US6733531B1 (en) * 2000-10-20 2004-05-11 Sdgi Holdings, Inc. Anchoring devices and implants for intervertebral disc augmentation
US20020169507A1 (en) * 2000-12-14 2002-11-14 David Malone Interbody spine fusion cage
US6402755B1 (en) 2000-12-21 2002-06-11 Perumala Corporation Plate system for bridging and stabilizing spaced apart bone segments
JP4133331B2 (en) 2001-02-04 2008-08-13 ウォーソー・オーソペディック・インコーポレーテッド Apparatus and method for inserting and deploying an expandable interbody spinal fusion implant
US7128760B2 (en) 2001-03-27 2006-10-31 Warsaw Orthopedic, Inc. Radially expanding interbody spinal fusion implants, instrumentation, and methods of insertion
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
CN1835720B (en) * 2001-07-25 2011-09-28 Disc整形外科技术股份有限公司 Deformable tools and implants
US6648917B2 (en) 2001-10-17 2003-11-18 Medicinelodge, Inc. Adjustable bone fusion implant and method
US7766947B2 (en) 2001-10-31 2010-08-03 Ortho Development Corporation Cervical plate for stabilizing the human spine
DE10154163A1 (en) * 2001-11-03 2003-05-22 Advanced Med Tech Device for straightening and stabilizing the spine
US20030093848P1 (en) * 2001-11-13 2003-05-15 Begonia Breeders Association B.V. Begonia plant named 'Fuga'
US7708776B1 (en) 2002-01-16 2010-05-04 Nuvasive, Inc. Intervertebral disk replacement system and methods
CA2477152A1 (en) * 2002-02-25 2003-09-04 Dzung H. Dinh Methods and apparatuses for promoting fusion of vertebrae
US6783547B2 (en) * 2002-04-05 2004-08-31 Howmedica Corp. Apparatus for fusing adjacent bone structures
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
US7001433B2 (en) 2002-05-23 2006-02-21 Pioneer Laboratories, Inc. Artificial intervertebral disc device
WO2003105673A2 (en) * 2002-06-17 2003-12-24 Trimedyne, Inc. Devices and methods for minimally invasive treatment of degenerated spinal discs
US6793678B2 (en) 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
FR2844179B1 (en) 2002-09-10 2004-12-03 Jean Taylor POSTERIOR VERTEBRAL SUPPORT KIT
MXPA05003044A (en) * 2002-09-18 2006-01-27 Asap Breathe Assist Pty Ltd A nasal cavity dilator.
US20140246023A1 (en) * 2006-02-28 2014-09-04 Paz Maryanka Nasal cavity dilator device
US7931674B2 (en) 2005-03-21 2011-04-26 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US8147548B2 (en) 2005-03-21 2012-04-03 Kyphon Sarl Interspinous process implant having a thread-shaped wing and method of implantation
US20080021468A1 (en) 2002-10-29 2008-01-24 Zucherman James F Interspinous process implants and methods of use
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US6723126B1 (en) 2002-11-01 2004-04-20 Sdgi Holdings, Inc. Laterally expandable cage
US6685742B1 (en) * 2002-11-12 2004-02-03 Roger P. Jackson Articulated anterior expandable spinal fusion cage system
US6974479B2 (en) * 2002-12-10 2005-12-13 Sdgi Holdings, Inc. System and method for blocking and/or retaining a prosthetic spinal implant
US20040210310A1 (en) * 2002-12-10 2004-10-21 Trieu Hai H. Implant system and method for intervertebral disc augmentation
CN1774220A (en) 2003-02-14 2006-05-17 德普伊斯派尔公司 In-situ formed intervertebral fusion device and method
US7235105B2 (en) * 2003-09-18 2007-06-26 Jackson Roger P Threaded center line cage with winged end gap
CA2536662A1 (en) * 2003-09-19 2005-03-31 Synecor, Llc Method and apparatus for treating diseased or fractured bone
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
US7513900B2 (en) * 2003-09-29 2009-04-07 Boston Scientific Scimed, Inc. Apparatus and methods for reducing compression bone fractures using high strength ribbed members
US9445916B2 (en) 2003-10-22 2016-09-20 Pioneer Surgical Technology, Inc. Joint arthroplasty devices having articulating members
US7670377B2 (en) 2003-11-21 2010-03-02 Kyphon Sarl Laterally insertable artifical vertebral disk replacement implant with curved spacer
US8821495B2 (en) * 2003-12-15 2014-09-02 Koninklijke Philips N.V. System and method for hyoidplasty
US7641664B2 (en) 2004-02-12 2010-01-05 Warsaw Orthopedic, Inc. Surgical instrumentation and method for treatment of a spinal structure
US6942698B1 (en) 2004-04-23 2005-09-13 Roger P. Jackson Spinal fusion interbody spacer
FR2871366A1 (en) 2004-06-09 2005-12-16 Ceravic Soc Par Actions Simpli PROSTHETIC EXPANSIBLE BONE IMPLANT
US7604638B2 (en) * 2004-06-21 2009-10-20 Depuy Spine, Inc. Instruments and methods for holding a bone plate
US7303074B2 (en) * 2004-09-22 2007-12-04 Dombrowski Trudy M Foldable organizer device
US20060089719A1 (en) * 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
US8597360B2 (en) 2004-11-03 2013-12-03 Neuropro Technologies, Inc. Bone fusion device
US20060095136A1 (en) * 2004-11-03 2006-05-04 Mcluen Design, Inc. Bone fusion device
WO2006066228A2 (en) * 2004-12-16 2006-06-22 Innovative Spinal Technologies Expandable implants for spinal disc replacement
US8007521B2 (en) 2005-02-17 2011-08-30 Kyphon Sarl Percutaneous spinal implants and methods
US8097018B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8057513B2 (en) 2005-02-17 2011-11-15 Kyphon Sarl Percutaneous spinal implants and methods
US8100943B2 (en) 2005-02-17 2012-01-24 Kyphon Sarl Percutaneous spinal implants and methods
US8038698B2 (en) 2005-02-17 2011-10-18 Kphon Sarl Percutaneous spinal implants and methods
US8157841B2 (en) 2005-02-17 2012-04-17 Kyphon Sarl Percutaneous spinal implants and methods
US20070276493A1 (en) 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous spinal implants and methods
US8096994B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8029567B2 (en) 2005-02-17 2011-10-04 Kyphon Sarl Percutaneous spinal implants and methods
US8034080B2 (en) 2005-02-17 2011-10-11 Kyphon Sarl Percutaneous spinal implants and methods
US7988709B2 (en) 2005-02-17 2011-08-02 Kyphon Sarl Percutaneous spinal implants and methods
US7998174B2 (en) 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
ATE547069T1 (en) * 2005-03-21 2012-03-15 Kyphon S Rl INTERSPINAL IMPLANT WITH EXPANDABLE WING
US8034079B2 (en) 2005-04-12 2011-10-11 Warsaw Orthopedic, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US7674296B2 (en) 2005-04-21 2010-03-09 Globus Medical, Inc. Expandable vertebral prosthesis
EP1874954B1 (en) * 2005-04-27 2017-12-27 Stout Medical Group, L.P. Expandable support device
US7727233B2 (en) 2005-04-29 2010-06-01 Warsaw Orthopedic, Inc. Spinous process stabilization devices and methods
US8080061B2 (en) * 2005-06-20 2011-12-20 Synthes Usa, Llc Apparatus and methods for treating bone
FR2887434B1 (en) 2005-06-28 2008-03-28 Jean Taylor SURGICAL TREATMENT EQUIPMENT OF TWO VERTEBRATES
US8591583B2 (en) 2005-08-16 2013-11-26 Benvenue Medical, Inc. Devices for treating the spine
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
AU2006279558B2 (en) 2005-08-16 2012-05-17 Izi Medical Products, Llc Spinal tissue distraction devices
US20070093899A1 (en) * 2005-09-28 2007-04-26 Christof Dutoit Apparatus and methods for treating bone
AU2006302190B2 (en) * 2005-10-10 2012-01-19 Chad Anthony Barrie Artificial spinal disc replacement system and method
WO2007067726A2 (en) * 2005-12-08 2007-06-14 Synthes (U.S.A.) Apparatus and methods for treating bone
US7988695B2 (en) 2005-12-21 2011-08-02 Theken Spine, Llc Articulated delivery instrument
US20070162132A1 (en) 2005-12-23 2007-07-12 Dominique Messerli Flexible elongated chain implant and method of supporting body tissue with same
US8083795B2 (en) 2006-01-18 2011-12-27 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US8262698B2 (en) 2006-03-16 2012-09-11 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US7976549B2 (en) 2006-03-23 2011-07-12 Theken Spine, Llc Instruments for delivering spinal implants
US8118844B2 (en) 2006-04-24 2012-02-21 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US20080021559A1 (en) * 2006-07-06 2008-01-24 Lanx, Llc Expandable spinal fusion cage
US7771473B2 (en) * 2006-07-06 2010-08-10 Lanx, Inc. Expandable spinal fusion cage
US8048119B2 (en) 2006-07-20 2011-11-01 Warsaw Orthopedic, Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US7731752B2 (en) * 2006-07-21 2010-06-08 Warsaw Orthopedic, Inc. Implant with nested members and methods of use
US9526525B2 (en) 2006-08-22 2016-12-27 Neuropro Technologies, Inc. Percutaneous system for dynamic spinal stabilization
KR101254745B1 (en) * 2006-08-31 2013-04-15 엘지디스플레이 주식회사 Liquid crystal display
US20080086115A1 (en) 2006-09-07 2008-04-10 Warsaw Orthopedic, Inc. Intercostal spacer device and method for use in correcting a spinal deformity
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
US8097019B2 (en) 2006-10-24 2012-01-17 Kyphon Sarl Systems and methods for in situ assembly of an interspinous process distraction implant
FR2908035B1 (en) 2006-11-08 2009-05-01 Jean Taylor INTEREPINE IMPLANT
US7879104B2 (en) 2006-11-15 2011-02-01 Warsaw Orthopedic, Inc. Spinal implant system
US11395626B2 (en) 2006-12-07 2022-07-26 DePuy Synthes Products, Inc. Sensor for intervertebral fusion indicia
US7955392B2 (en) 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
US20080154374A1 (en) * 2006-12-20 2008-06-26 Robert David Labrom Joint implant and a surgical method associated therewith
US7976579B2 (en) * 2007-01-10 2011-07-12 Warsaw Orthopedic, Inc. Ratcheting nucleus replacement
CA2678006C (en) 2007-02-21 2014-10-14 Benvenue Medical, Inc. Devices for treating the spine
US8480715B2 (en) 2007-05-22 2013-07-09 Zimmer Spine, Inc. Spinal implant system and method
US8518115B2 (en) 2007-11-16 2013-08-27 DePuy Synthes Products, LLC Porous containment device and associated method for stabilization of vertebral compression fractures
US20090198338A1 (en) 2008-02-04 2009-08-06 Phan Christopher U Medical implants and methods
US8267939B2 (en) 2008-02-28 2012-09-18 Stryker Spine Tool for implanting expandable intervertebral implant
US8114136B2 (en) 2008-03-18 2012-02-14 Warsaw Orthopedic, Inc. Implants and methods for inter-spinous process dynamic stabilization of a spinal motion segment
WO2009125242A1 (en) * 2008-04-08 2009-10-15 Vexim Apparatus for restoration of the spine and methods of use thereof
ES2361099B1 (en) * 2008-05-26 2012-05-08 Rudolf Morgenstern Lopez "INTERVERTEBRAL PROSTHESIS"
US8110004B2 (en) * 2008-08-21 2012-02-07 The Trustees Of The Stevens Institute Of Technology Expandable interbody fusion cage with rotational insert
US8114131B2 (en) 2008-11-05 2012-02-14 Kyphon Sarl Extension limiting devices and methods of use for the spine
US8721723B2 (en) 2009-01-12 2014-05-13 Globus Medical, Inc. Expandable vertebral prosthesis
PL2405835T3 (en) 2009-03-12 2018-05-30 Vexim Apparatus for bone restoration of the spine
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
US8911497B2 (en) 2009-04-09 2014-12-16 DePuy Synthes Products, LLC Minimally invasive spine augmentation and stabilization system and method
US8372117B2 (en) 2009-06-05 2013-02-12 Kyphon Sarl Multi-level interspinous implants and methods of use
US8157842B2 (en) 2009-06-12 2012-04-17 Kyphon Sarl Interspinous implant and methods of use
US8771317B2 (en) 2009-10-28 2014-07-08 Warsaw Orthopedic, Inc. Interspinous process implant and method of implantation
WO2011059498A1 (en) 2009-11-11 2011-05-19 Nuvasive, Inc. Surgical access system and related methods
US8114132B2 (en) 2010-01-13 2012-02-14 Kyphon Sarl Dynamic interspinous process device
US8317831B2 (en) 2010-01-13 2012-11-27 Kyphon Sarl Interspinous process spacer diagnostic balloon catheter and methods of use
US8147526B2 (en) 2010-02-26 2012-04-03 Kyphon Sarl Interspinous process spacer diagnostic parallel balloon catheter and methods of use
US9301850B2 (en) 2010-04-12 2016-04-05 Globus Medical, Inc. Expandable vertebral implant
US8870880B2 (en) 2010-04-12 2014-10-28 Globus Medical, Inc. Angling inserter tool for expandable vertebral implant
US8591585B2 (en) 2010-04-12 2013-11-26 Globus Medical, Inc. Expandable vertebral implant
US8282683B2 (en) 2010-04-12 2012-10-09 Globus Medical, Inc. Expandable vertebral implant
US8535380B2 (en) 2010-05-13 2013-09-17 Stout Medical Group, L.P. Fixation device and method
US8641769B2 (en) 2010-07-15 2014-02-04 Spine Wave, Inc. Plastically deformable inter-osseous device
US8814908B2 (en) 2010-07-26 2014-08-26 Warsaw Orthopedic, Inc. Injectable flexible interspinous process device system
EP2608747A4 (en) 2010-08-24 2015-02-11 Flexmedex Llc Support device and method for use
WO2012047712A1 (en) * 2010-10-05 2012-04-12 Alphatec Spine, Inc. Minimally invasive intervertebral systems and methods
WO2012068541A2 (en) * 2010-11-18 2012-05-24 Pavilion Medical Innovations Tissue restraining devices and methods of use
WO2012112596A1 (en) 2011-02-14 2012-08-23 Imds Corporation Expandable intervertebral implants
US9308099B2 (en) 2011-02-14 2016-04-12 Imds Llc Expandable intervertebral implants and instruments
US8591548B2 (en) 2011-03-31 2013-11-26 Warsaw Orthopedic, Inc. Spinous process fusion plate assembly
US9414933B2 (en) 2011-04-07 2016-08-16 Vexim Sa Expandable orthopedic device
US8591549B2 (en) 2011-04-08 2013-11-26 Warsaw Orthopedic, Inc. Variable durometer lumbar-sacral implant
WO2012178018A2 (en) 2011-06-24 2012-12-27 Benvenue Medical, Inc. Devices and methods for treating bone tissue
US10292830B2 (en) 2011-08-09 2019-05-21 Neuropro Technologies, Inc. Bone fusion device, system and method
US10420654B2 (en) 2011-08-09 2019-09-24 Neuropro Technologies, Inc. Bone fusion device, system and method
US9358123B2 (en) 2011-08-09 2016-06-07 Neuropro Spinal Jaxx, Inc. Bone fusion device, apparatus and method
EP2729092B1 (en) 2011-08-16 2016-09-21 Stryker European Holdings I, LLC Expandable implant
US9198769B2 (en) 2011-12-23 2015-12-01 Pioneer Surgical Technology, Inc. Bone anchor assembly, bone plate system, and method
US9532883B2 (en) 2012-04-13 2017-01-03 Neuropro Technologies, Inc. Bone fusion device
US10159583B2 (en) 2012-04-13 2018-12-25 Neuropro Technologies, Inc. Bone fusion device
US9393126B2 (en) * 2012-04-20 2016-07-19 Peter L. Mayer Bilaterally placed disc prosthesis for spinal implant and method of bilateral placement
US9968455B2 (en) * 2012-04-27 2018-05-15 Howmedica Osteonics Corp. Multiple component bone void filling implant
US9364339B2 (en) * 2012-04-30 2016-06-14 Peter L. Mayer Unilaterally placed expansile spinal prosthesis
RU2014146705A (en) * 2012-05-29 2016-07-20 ЭнЭлТи-СПАЙН ЛТД. Laterally variable implant
US9278008B2 (en) 2012-05-30 2016-03-08 Globus Medical, Inc. Expandable interbody spacer
US9044342B2 (en) 2012-05-30 2015-06-02 Globus Medical, Inc. Expandable interbody spacer
US8940052B2 (en) 2012-07-26 2015-01-27 DePuy Synthes Products, LLC Expandable implant
US20140067069A1 (en) 2012-08-30 2014-03-06 Interventional Spine, Inc. Artificial disc
US9320611B2 (en) * 2012-10-20 2016-04-26 Carlos Andres Rodriguez Surgically implantable joint spacer
US10258480B1 (en) 2012-10-20 2019-04-16 Carlos Andres Rodriguez Surgically implantable joint spacer
US10342675B2 (en) 2013-03-11 2019-07-09 Stryker European Holdings I, Llc Expandable implant
US10022240B2 (en) * 2013-03-12 2018-07-17 Morgan Packard Lorio Vertically expandable intervertebral cage, deployment devices, and methods of using the same
US10085783B2 (en) 2013-03-14 2018-10-02 Izi Medical Products, Llc Devices and methods for treating bone tissue
MX366061B (en) 2013-03-15 2019-06-26 Neuropro Tech Inc Bodiless bone fusion device, apparatus and method.
US11311312B2 (en) 2013-03-15 2022-04-26 Medtronic, Inc. Subcutaneous delivery tool
US11452614B2 (en) 2013-08-29 2022-09-27 Adcura, Inc. Expandable and adjustable lordosis interbody fusion system
ES2882166T3 (en) 2013-08-29 2021-12-01 Spineex Inc Expandable and adjustable lordosis intervertebral fusion system
US9539041B2 (en) 2013-09-12 2017-01-10 DePuy Synthes Products, Inc. Minimally invasive biomaterial injection system
FR3015221B1 (en) 2013-12-23 2017-09-01 Vexim EXPANSIBLE INTRAVERTEBRAL IMPLANT SYSTEM WITH POSTERIOR PEDICULAR FIXATION
JP6537535B2 (en) 2014-06-20 2019-07-03 エーエスエーピー ブレスアシスト ピーティーワイ リミテッド Nose dilator
AU2015397594B2 (en) 2015-06-05 2021-01-28 Asap Breatheassist Pty Ltd Nasal dilators
US9913727B2 (en) 2015-07-02 2018-03-13 Medos International Sarl Expandable implant
EP3328474B1 (en) 2015-07-31 2020-12-09 ASAP Breatheassist Pty Ltd Nasal devices
US9713536B2 (en) * 2015-08-12 2017-07-25 Warsaw Orthopedic, Inc. Expandable spinal implant and method of implanting same
US10105238B2 (en) 2015-08-25 2018-10-23 Imds Llc Expandable intervertebral implants
US10299837B2 (en) * 2016-03-08 2019-05-28 West End Bay Partners, Llc Sacroiliac joint stabilization and fixation devices and related methods
TWI609669B (en) * 2016-04-18 2018-01-01 Spirit Spine Holdings Corporation Inc Bone fixation device
WO2018081322A1 (en) 2016-10-25 2018-05-03 Imds Llc Methods and instrumentation for intervertebral cage expansion
US10537436B2 (en) 2016-11-01 2020-01-21 DePuy Synthes Products, Inc. Curved expandable cage
US10888433B2 (en) 2016-12-14 2021-01-12 DePuy Synthes Products, Inc. Intervertebral implant inserter and related methods
US10973657B2 (en) 2017-01-18 2021-04-13 Neuropro Technologies, Inc. Bone fusion surgical system and method
US10213321B2 (en) 2017-01-18 2019-02-26 Neuropro Technologies, Inc. Bone fusion system, device and method including delivery apparatus
US10111760B2 (en) 2017-01-18 2018-10-30 Neuropro Technologies, Inc. Bone fusion system, device and method including a measuring mechanism
US10729560B2 (en) 2017-01-18 2020-08-04 Neuropro Technologies, Inc. Bone fusion system, device and method including an insertion instrument
US10940016B2 (en) 2017-07-05 2021-03-09 Medos International Sarl Expandable intervertebral fusion cage
TWI635842B (en) * 2017-07-10 2018-09-21 國立臺灣大學 Spinal cage
JP6941175B2 (en) 2017-08-30 2021-09-29 富士フイルム株式会社 Device for cell transplantation and its manufacturing method
AU2018327353A1 (en) 2017-09-08 2020-03-19 Pioneer Surgical Technology, Inc. Intervertebral implants, instruments, and methods
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
US10864029B2 (en) 2018-01-26 2020-12-15 West End Bay Partners, Llc Sacroiliac joint stabilization and fixation devices and related methods
US10945859B2 (en) 2018-01-29 2021-03-16 Amplify Surgical, Inc. Expanding fusion cages
US11806250B2 (en) 2018-02-22 2023-11-07 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US11129728B1 (en) 2018-10-03 2021-09-28 Guillermo Molina Surgically implantable joint spacer
USD955579S1 (en) 2019-04-26 2022-06-21 Warsaw Orthopedic, Inc. Surgical implant
USD948048S1 (en) 2019-04-26 2022-04-05 Warsaw Orthopedic, Inc. Surgical implant
TWD206924S (en) 2019-06-13 2020-09-01 澳大利亞商Asap呼吸援助有限公司 Nasal dilator device
JP2022544680A (en) 2019-08-15 2022-10-20 アドキュラ・インコーポレーテッド Convertible Biaxial Adjustable Interbody Fusion Spinal System
EP4013357A4 (en) 2019-08-15 2023-09-06 Adcura, Inc. Dual-axis adjustable spinal systems and interbody fusion devices with fixation
US11648132B2 (en) 2019-09-24 2023-05-16 Adcura, Inc Surgical instrument for operating spinal implant system with dual axis adjustability and method of operating same
US11684485B1 (en) * 2020-02-04 2023-06-27 Guillermo Molina Surgically implantable joint spacer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260044A1 (en) * 1986-08-29 1988-03-16 John Anthony Norman Shepperd Spinal implant
EP0304305A1 (en) * 1987-08-20 1989-02-22 RayMedica, Inc. Prosthetic disc

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US725874A (en) * 1903-02-02 1903-04-21 Charles Riley Plumber's clamp for wiping joints.
US2226078A (en) * 1939-09-29 1940-12-24 Hilbert C Spahn Expanding mandrel
US3030903A (en) * 1959-07-06 1962-04-24 Thomas L Morris Welding jig
DE1906284A1 (en) * 1969-02-08 1970-09-03 Dr Esfandiar Shahrestani Endoprosthesis, especially for hip joints
CA992255A (en) * 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US3986383A (en) * 1974-01-02 1976-10-19 Petteys Howard A Expander tool
IL48826A (en) * 1976-01-13 1978-08-31 Aginsky Yacov Intramedullary compression nail for the treatment of bone fractures
SU662082A1 (en) * 1977-12-09 1979-05-15 Тартуский Ордена Трудового Красного Знамени Государственный Университет Fixative for treating tubular bone fractures
US4465220A (en) * 1979-11-05 1984-08-14 The Boeing Company Device for supporting weld underbead
SU906548A1 (en) * 1980-06-05 1982-02-23 Тернопольский медицинский институт Intramedullary fixing device
GB2083754B (en) * 1980-09-15 1984-04-26 Rezaian Seyed Mahmoud Spinal fixator
US4309777A (en) * 1980-11-13 1982-01-12 Patil Arun A Artificial intervertebral disc
SU1122304A1 (en) * 1982-07-26 1984-11-07 Чувашский государственный университет им.И.Н.Ульянова Fixative for osteosynthesis of tubular bones
SU1127905A1 (en) * 1983-05-24 1984-12-07 Институт проблем литья АН УССР Method for smelting steel in hearth furnaces
US4553273A (en) * 1983-11-23 1985-11-19 Henry Ford Hospital Vertebral body prosthesis and spine stabilizing method
FR2575059B1 (en) * 1984-12-21 1988-11-10 Daher Youssef SHORING DEVICE FOR USE IN A VERTEBRAL PROSTHESIS
CH671691A5 (en) * 1987-01-08 1989-09-29 Sulzer Ag
US4834757A (en) * 1987-01-22 1989-05-30 Brantigan John W Prosthetic implant
CA1283501C (en) * 1987-02-12 1991-04-30 Thomas P. Hedman Artificial spinal disc
US4863477A (en) * 1987-05-12 1989-09-05 Monson Gary L Synthetic intervertebral disc prosthesis
DE8711992U1 (en) * 1987-09-04 1987-10-15 Aesculap-Werke Ag Vormals Jetter & Scheerer, 7200 Tuttlingen, De
DE8807485U1 (en) * 1988-06-06 1989-08-10 Mecron Medizinische Produkte Gmbh, 1000 Berlin, De
CA1333209C (en) * 1988-06-28 1994-11-29 Gary Karlin Michelson Artificial spinal fusion implants
FR2639823A1 (en) * 1988-12-06 1990-06-08 Garcia Alain Replacement of the nucleus of the intervertebral disc by a polyurethane polymerised in situ
US4932975A (en) * 1989-10-16 1990-06-12 Vanderbilt University Vertebral prosthesis
US5059193A (en) * 1989-11-20 1991-10-22 Spine-Tech, Inc. Expandable spinal implant and surgical method
US5171278A (en) * 1991-02-22 1992-12-15 Madhavan Pisharodi Middle expandable intervertebral disk implants
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
US5290312A (en) * 1991-09-03 1994-03-01 Alphatec Artificial vertebral body

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260044A1 (en) * 1986-08-29 1988-03-16 John Anthony Norman Shepperd Spinal implant
EP0304305A1 (en) * 1987-08-20 1989-02-22 RayMedica, Inc. Prosthetic disc

Cited By (262)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080155A (en) * 1988-06-13 2000-06-27 Michelson; Gary Karlin Method of inserting and preloading spinal implants
US5562738A (en) * 1992-01-06 1996-10-08 Danek Medical, Inc. Intervertebral disk arthroplasty device
US5425773A (en) * 1992-01-06 1995-06-20 Danek Medical, Inc. Intervertebral disk arthroplasty device
US5258031A (en) * 1992-01-06 1993-11-02 Danek Medical Intervertebral disk arthroplasty
US6436098B1 (en) 1993-06-10 2002-08-20 Sofamor Danek Holdings, Inc. Method for inserting spinal implants and for securing a guard to the spine
DE4323956C1 (en) * 1993-07-19 1994-10-27 Eska Medical Gmbh & Co Fusion dowel for vertebrae
EP0635246A1 (en) * 1993-07-19 1995-01-25 ESKA Implants GmbH & Co. Dowel for fusing vertebral bodies
WO1995008306A1 (en) * 1993-09-21 1995-03-30 Synthes Ag, Chur Implant for the intervertebral space
EP1447061A1 (en) * 1993-09-21 2004-08-18 SYNTHES AG Chur Implant for the intervertebral space
EP1464306A3 (en) * 1993-09-21 2005-08-31 SYNTHES AG Chur Implant for the intervertebral space
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
EP0725607A1 (en) * 1993-10-12 1996-08-14 Danek Medical, Inc. Anterior interbody fusion device
EP0725607A4 (en) * 1993-10-12 1998-01-14 Danek Medical Inc Anterior interbody fusion device
FR2715293A1 (en) * 1994-01-26 1995-07-28 Biomat Vertebral interbody fusion cage.
EP0664994A1 (en) * 1994-01-26 1995-08-02 BIOMAT(S.a.r.l.) Interbody vertebral cage
FR2717068A1 (en) * 1994-03-14 1995-09-15 Biomat Intersomatic cage insertable between two vertebral bodies
US5653762A (en) * 1994-03-18 1997-08-05 Pisharodi; Madhavan Method of stabilizing adjacent vertebrae with rotating, lockable, middle-expanded intervertebral disk stabilizer
US5893890A (en) * 1994-03-18 1999-04-13 Perumala Corporation Rotating, locking intervertebral disk stabilizer and applicator
WO1996040016A2 (en) * 1994-03-18 1996-12-19 Madhavan Pisharodi Intervertebral disk stabilizer and instrument for reduction of spondylolisthesis
WO1996040016A3 (en) * 1994-03-18 1997-02-13 Madhavan Pisharodi Intervertebral disk stabilizer and instrument for reduction of spondylolisthesis
US5653761A (en) * 1994-03-18 1997-08-05 Pisharodi; Madhavan Method of lumbar intervertebral disk stabilization
US5658336A (en) * 1994-03-18 1997-08-19 Pisharodi; Madhavan Rotating, locking, middle-expanded intervertebral disk stabilizer
WO1995025487A1 (en) * 1994-03-18 1995-09-28 Madhavan Pisharodi Middle expanded, removable intervertebral disk stabilizer and method of lumbar intervertebral disk stabilization
DE19580181B4 (en) * 1994-03-23 2004-10-28 Schnorrenberg Chirurgiemechanik Gmbh Positioning and support device for spinal column - has shear lift bar with operating screw between support plates for support and has tool extension on side support member
WO1995025485A1 (en) * 1994-03-23 1995-09-28 Schnorrenberg Chirurgiemechanik Gmbh Positioning and support device for the spinal column
FR2718955A1 (en) * 1994-04-25 1995-10-27 Soprane Sa Intersomatic cage for fusion of lumbar vertebrae
DE4416605C1 (en) * 1994-05-11 1995-06-08 Aesculap Ag Inter-vertebral implant
FR2719763A1 (en) * 1994-05-11 1995-11-17 Jean Taylor Vertebral implant.
WO1995031158A1 (en) * 1994-05-11 1995-11-23 Jean Taylor Vertebral implant
FR2722679A1 (en) * 1994-07-25 1996-01-26 Daniel Felman Expansible arthrodesis implant for insertion between vertebrae
WO1996027348A1 (en) * 1995-03-08 1996-09-12 Synthes Ag, Chur Intervertebral implant
US6059829A (en) * 1995-03-08 2000-05-09 Synthese Intervertebral implant
US6375655B1 (en) 1995-03-27 2002-04-23 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
US6077265A (en) * 1995-04-21 2000-06-20 Werding; Gerd Nail for fixing the position and shape of broken long bones
US6264655B1 (en) 1995-06-07 2001-07-24 Madhavan Pisharodi Cervical disk and spinal stabilizer
US8075622B2 (en) 1995-10-16 2011-12-13 Warsaw Orthopedic, Inc Intervertebral spacers
US7981156B2 (en) 1995-10-16 2011-07-19 Warsaw Orthopedic, Inc. Bone grafts
US6423095B1 (en) 1995-10-16 2002-07-23 Sdgi Holdings, Inc. Intervertebral spacers
US7311734B2 (en) 1995-10-16 2007-12-25 Warsaw Orthopedic, Inc. Intervertebral spacers
US7276081B1 (en) 1995-10-16 2007-10-02 Warsaw Orthopedic, Inc. Bone grafts
WO1998055051A1 (en) * 1995-12-05 1998-12-10 Metagen, Llc Modular prosthesis
US5858020A (en) * 1995-12-05 1999-01-12 Metagen, Llc Modular prosthesis
US6019793A (en) * 1996-10-21 2000-02-01 Synthes Surgical prosthetic device
WO1998017207A1 (en) * 1996-10-21 1998-04-30 Synthes Ag Chur Surgical prosthetic device
EP0853932A3 (en) * 1997-01-21 1998-10-07 Spinal Innovations Fusion implant
US6127597A (en) * 1997-03-07 2000-10-03 Discotech N.V. Systems for percutaneous bone and spinal stabilization, fixation and repair
EP1905392A1 (en) 1997-03-07 2008-04-02 Disc-O-Tech Medical Technologies, Ltd. System for percutaneous bone and spinal stabilization, fixation and repair
WO1998038918A1 (en) 1997-03-07 1998-09-11 Mordechay Beyar Systems for percutaneous bone and spinal stabilization, fixation and repair
FR2760355A1 (en) * 1997-03-07 1998-09-11 Serge Schrayer Intersomatic cage, e.g. for fusion of vertebrae or joint bones
DE19720241B4 (en) * 1997-05-15 2005-12-29 Eska Implants Gmbh & Co. Interbody fusion implant
US7285135B2 (en) 1997-12-10 2007-10-23 Warsaw Orthopedic, Inc. Osteogenic fusion device
WO1999029271A1 (en) * 1997-12-10 1999-06-17 Sdgi Holdings, Inc. Osteogenic fusion device
US8177848B2 (en) 1997-12-10 2012-05-15 Warsaw Orthopedic, Inc. Osteogenic fusion device
US7763079B2 (en) 1997-12-10 2010-07-27 Warsaw Orthopedic, Inc. Osteogenic fusion device
US6648916B1 (en) 1997-12-10 2003-11-18 Sdgi Holdings, Inc. Osteogenic fusion device
US8685102B2 (en) 1997-12-10 2014-04-01 Warsaw Orthopedic, Inc. Osteogenic fusion device
US7179293B2 (en) 1997-12-10 2007-02-20 Warsaw Orthopedic, Inc. Osteogenic fusion device
DE19816832C1 (en) * 1998-04-16 2000-01-20 Aesculap Ag & Co Kg Surgical vertebral implant
US7270681B2 (en) 1998-04-23 2007-09-18 Warsaw Orthopedic, Inc. Articulating spinal implant
US6179874B1 (en) 1998-04-23 2001-01-30 Cauthen Research Group, Inc. Articulating spinal implant
US6440168B1 (en) 1998-04-23 2002-08-27 Sdgi Holdings, Inc. Articulating spinal implant
US6679915B1 (en) 1998-04-23 2004-01-20 Sdgi Holdings, Inc. Articulating spinal implant
US6846328B2 (en) 1998-04-23 2005-01-25 Sdgi Holdings, Inc. Articulating spinal implant
US6019792A (en) * 1998-04-23 2000-02-01 Cauthen Research Group, Inc. Articulating spinal implant
US6436140B1 (en) * 1998-08-28 2002-08-20 Sofamor S.N.C. Expandable interbody fusion cage and method for insertion
FR2783702A1 (en) * 1998-09-29 2000-03-31 Maurice Bertholet Self-locking prosthesis for bone insert has heat activated anchor flanges formed on central core
US7993403B2 (en) 1998-10-29 2011-08-09 Warsaw Orthopedic, Inc. Expandable intervertebral spacers
WO2000025706A1 (en) * 1998-10-29 2000-05-11 Sdgi Holdings, Inc. Expandable intervertebral spacers
US6833006B2 (en) 1998-10-29 2004-12-21 Sdgi Holdings, Inc. Expandable intervertebral spacers
US7655042B2 (en) 1998-10-29 2010-02-02 Warsaw Orthopedic, Inc. Expandable intervertebral spacers
US6395031B1 (en) 1998-10-29 2002-05-28 Sdgi Holdings, Inc. Expandable intervertebral spacers
EP1459711A1 (en) * 1998-10-29 2004-09-22 SDGI Holdings, Inc. Expandable intervertebral spacers
US6193757B1 (en) 1998-10-29 2001-02-27 Sdgi Holdings, Inc. Expandable intervertebral spacers
USRE47427E1 (en) 1999-01-27 2019-06-11 Medtronic Holding Company Sárl Expandable intervertebral spacer
US7097648B1 (en) 1999-01-27 2006-08-29 Disc-O-Tech Medical Technologies Ltd. Expandable element delivery system
WO2000045752A1 (en) * 1999-02-04 2000-08-10 Aesculap Ag & Co. Kg Rehabitable linking screw for arthrodesis of a bone joint for stabilising two vertebrae
US6800092B1 (en) 1999-02-26 2004-10-05 Lytton A. Williams Method and apparatus for intervertebral implant anchorage
US6113638A (en) * 1999-02-26 2000-09-05 Williams; Lytton A. Method and apparatus for intervertebral implant anchorage
US6241770B1 (en) 1999-03-05 2001-06-05 Gary K. Michelson Interbody spinal fusion implant having an anatomically conformed trailing end
US9078768B2 (en) 1999-03-05 2015-07-14 Warsaw Orthopedic, Inc. Arcuate interbody spinal fusion implant having a reduced width and an anatomically conformed trailing end
US8882835B2 (en) 1999-03-05 2014-11-11 Warsaw Orthopedic, Inc. Interbody spinal fusion implant having an anatomically conformed trailing end
US8343220B2 (en) 1999-05-05 2013-01-01 Warsaw Orthopedic, Inc. Nested interbody spinal fusion implants
US7156875B2 (en) 2000-04-19 2007-01-02 Warsaw Orthopedic, Inc. Arcuate artificial hemi-lumbar interbody spinal fusion implant having an asymmetrical leading end
US7387643B2 (en) 2000-04-19 2008-06-17 Warsaw Orthopedic, Inc. Method for installation of artificial hemi-lumbar interbody spinal fusion implant having an asymmetrical leading end
US7022137B2 (en) 2000-04-19 2006-04-04 Sdgi Holdings, Inc. Bone hemi-lumbar interbody spinal fusion implant having an asymmetrical leading end and method of installation thereof
US8834569B2 (en) 2000-04-19 2014-09-16 Warsaw Orthopedic, Inc. Artificial hemi-lumbar interbody spinal fusion cage having an asymmetrical leading end
US6666890B2 (en) 2000-04-19 2003-12-23 Gary K. Michelson Bone hemi-lumbar interbody spinal implant having an asymmetrical leading end and method of installation thereof
US8323340B2 (en) 2000-04-19 2012-12-04 Warsaw Orthopedic, Inc. Artificial hemi-lumbar interbody spinal implant having an asymmetrical leading end
US6350283B1 (en) 2000-04-19 2002-02-26 Gary K. Michelson Bone hemi-lumbar interbody spinal implant having an asymmetrical leading end and method of installation thereof
US6761738B1 (en) 2000-09-19 2004-07-13 Sdgi Holdings, Inc. Reinforced molded implant formed of cortical bone
US7618460B2 (en) 2000-09-19 2009-11-17 Warsaw Orthopedic, Inc. Reinforced molded implant formed of cortical bone
US8177845B2 (en) 2000-10-24 2012-05-15 Warsaw Orthopedic, Inc. Osteogenic packing device and method
US7550011B2 (en) 2000-10-24 2009-06-23 Warsaw Orthopedic, Inc. Osteogenic packing device and method
US6780192B2 (en) 2000-10-24 2004-08-24 Sdgi Holdings, Inc. Osteogenic packing device and method
US8926703B2 (en) 2001-04-02 2015-01-06 Warsaw Orthopedic, Inc. Spinal fusion implant with bone screws and a bone screw lock
US7935149B2 (en) 2001-04-02 2011-05-03 Warsaw Orthopedic, Inc. Spinal fusion implant with bone screws
US8137403B2 (en) 2001-04-02 2012-03-20 Warsaw Orthopedic, Inc. Hemi-interbody spinal fusion implants manufactured from a major long bone ring
US9463098B2 (en) 2001-04-02 2016-10-11 Warsaw Orthopedic, Inc. Spinal fusion implant with bone screws and a bone screw lock
US8632594B2 (en) 2002-03-30 2014-01-21 Infinity Orthopaedics Company, Ltd Intervertebral device and method of use
US7717959B2 (en) 2002-03-30 2010-05-18 Lytton William Intervertebral device and method of use
US8409286B2 (en) 2002-09-23 2013-04-02 Warsaw Orthopedic, Inc. Expandable spinal fusion device and methods of promoting spinal fusion
US7018415B1 (en) 2002-09-23 2006-03-28 Sdgi Holdings, Inc. Expandable spinal fusion device and methods of promoting spinal fusion
EP1402853A3 (en) * 2002-09-27 2006-03-22 Depuy Products, Inc. Concave resurfacing glenoid prosthesis
US7329284B2 (en) 2002-09-27 2008-02-12 Depuy Products, Inc. Concave resurfacing prosthesis
US9180016B2 (en) 2002-09-27 2015-11-10 DePuy Synthes Products, Inc. Concave resurfacing prosthesis kit
US8673015B2 (en) 2002-09-27 2014-03-18 DePuy Synthes Products, LLC Concave resurfacing prosthesis
US8992541B2 (en) 2003-03-14 2015-03-31 DePuy Synthes Products, LLC Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US10799278B2 (en) 2003-03-14 2020-10-13 DePuy Synthes Products, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US9186194B2 (en) 2003-03-14 2015-11-17 DePuy Synthes Products, Inc. Hydraulic device for the injection of bone cement in percutaneous vertebroplasty
US10485597B2 (en) 2003-03-31 2019-11-26 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US9839460B2 (en) 2003-03-31 2017-12-12 DePuy Synthes Products, Inc. Remotely-activated vertebroplasty injection device
US10039585B2 (en) 2003-06-17 2018-08-07 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8956368B2 (en) 2003-06-17 2015-02-17 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US9504508B2 (en) 2003-06-17 2016-11-29 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US9750840B2 (en) 2004-03-21 2017-09-05 DePuy Synthes Products, Inc. Methods, materials and apparatus for treating bone and other tissue
US8809418B2 (en) 2004-03-21 2014-08-19 DePuy Synthes Products, LLC Methods, materials and apparatus for treating bone and other tissue
US8608804B2 (en) 2004-03-29 2013-12-17 Nuvasive, Inc. Systems and methods for spinal fusion
US8814940B2 (en) 2004-03-29 2014-08-26 Nuvasive, Inc. Systems and methods for spinal fusion
US9474627B2 (en) 2004-03-29 2016-10-25 Nuvasive, Inc. Systems and methods for spinal fusion
US9744053B2 (en) 2004-03-29 2017-08-29 Nuvasive, Inc. Systems and methods for spinal fusion
US9180021B2 (en) 2004-03-29 2015-11-10 Nuvasive, Inc. Systems and methods for spinal fusion
US9259329B2 (en) 2004-09-21 2016-02-16 Stout Medical Group, L.P. Expandable support device and method of use
US11051954B2 (en) 2004-09-21 2021-07-06 Stout Medical Group, L.P. Expandable support device and method of use
US9314349B2 (en) 2004-09-21 2016-04-19 Stout Medical Group, L.P. Expandable support device and method of use
US7799080B2 (en) 2005-04-22 2010-09-21 Doty Keith L Spinal disc prosthesis and methods of use
US7361192B2 (en) 2005-04-22 2008-04-22 Doty Keith L Spinal disc prosthesis and methods of use
US7655043B2 (en) 2005-04-29 2010-02-02 Warsaw Orthopedic, Inc. Expandable spinal implant and associated instrumentation
US7749270B2 (en) 2005-04-29 2010-07-06 Warsaw Orthopedic, Inc. Expandable intervertebral implant and associated instrumentation
WO2006118867A1 (en) * 2005-04-29 2006-11-09 Warsaw Orthopedic, Inc. Expandable intervertebral implant and associated instrumentation
US9770339B2 (en) 2005-07-14 2017-09-26 Stout Medical Group, L.P. Expandable support device and method of use
US8870960B2 (en) 2005-07-28 2014-10-28 Nuvasive, Inc. Total disc replacement system and related methods
US9168149B2 (en) 2005-07-28 2015-10-27 NaVasive, Inc. Total disc replacement system and related methods
US9610171B2 (en) 2005-07-28 2017-04-04 Nuvasive, Inc. Total disc replacement system and related methods
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8435295B2 (en) 2005-09-26 2013-05-07 Infinity Orthopaedics Company System and method for intervertebral implant delivery and removal
US10631906B2 (en) 2005-11-22 2020-04-28 DePuy Synthes Products, Inc. Apparatus for transferring a viscous material
US9259696B2 (en) 2005-11-22 2016-02-16 DePuy Synthes Products, Inc. Mixing apparatus having central and planetary mixing elements
US10758289B2 (en) 2006-05-01 2020-09-01 Stout Medical Group, L.P. Expandable support device and method of use
US11141208B2 (en) 2006-05-01 2021-10-12 Stout Medical Group, L.P. Expandable support device and method of use
US10813677B2 (en) 2006-05-01 2020-10-27 Stout Medical Group, L.P. Expandable support device and method of use
US9642932B2 (en) 2006-09-14 2017-05-09 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US10272174B2 (en) 2006-09-14 2019-04-30 DePuy Synthes Products, Inc. Bone cement and methods of use thereof
US8950929B2 (en) 2006-10-19 2015-02-10 DePuy Synthes Products, LLC Fluid delivery system
US10494158B2 (en) 2006-10-19 2019-12-03 DePuy Synthes Products, Inc. Fluid delivery system
US11712345B2 (en) 2006-12-07 2023-08-01 DePuy Synthes Products, Inc. Intervertebral implant
US11660206B2 (en) 2006-12-07 2023-05-30 DePuy Synthes Products, Inc. Intervertebral implant
US11642229B2 (en) 2006-12-07 2023-05-09 DePuy Synthes Products, Inc. Intervertebral implant
US11497618B2 (en) 2006-12-07 2022-11-15 DePuy Synthes Products, Inc. Intervertebral implant
US11432942B2 (en) 2006-12-07 2022-09-06 DePuy Synthes Products, Inc. Intervertebral implant
US9186261B2 (en) 2007-03-07 2015-11-17 Nuvasive, Inc. System and methods for spinal fusion
US9918852B2 (en) 2007-03-07 2018-03-20 Nuvasive, Inc. System and methods for spinal fusion
US11638652B2 (en) 2007-03-07 2023-05-02 Nuvasive, Inc. Systems and methods for spinal fusion
US9486329B2 (en) 2007-03-07 2016-11-08 Nuvasive, Inc. System and methods for spinal fusion
US11622868B2 (en) 2007-06-26 2023-04-11 DePuy Synthes Products, Inc. Highly lordosed fusion cage
US11737881B2 (en) 2008-01-17 2023-08-29 DePuy Synthes Products, Inc. Expandable intervertebral implant and associated method of manufacturing the same
US10842646B2 (en) 2008-02-29 2020-11-24 Nuvasive, In.C Implants and methods for spinal fusion
US9907672B1 (en) 2008-02-29 2018-03-06 Nuvasive, Inc. Implants and methods for spinal fusion
US9168152B2 (en) 2008-02-29 2015-10-27 Nuvasive, Inc. Implants and methods for spinal fusion
US11602438B2 (en) 2008-04-05 2023-03-14 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11712341B2 (en) 2008-04-05 2023-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11617655B2 (en) 2008-04-05 2023-04-04 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11701234B2 (en) 2008-04-05 2023-07-18 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11707359B2 (en) 2008-04-05 2023-07-25 DePuy Synthes Products, Inc. Expandable intervertebral implant
US11712342B2 (en) 2008-04-05 2023-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant
FR2937245A1 (en) * 2008-10-22 2010-04-23 Marc Palmieri Orthopedic implant e.g. glenoid implant support base, press-fit type fixation device for e.g. spongy bone of scapula, has plot that is expandable under force exerted on area of plot after implementation of support part of implant
US10292828B2 (en) 2008-11-12 2019-05-21 Stout Medical Group, L.P. Fixation device and method
US10285820B2 (en) 2008-11-12 2019-05-14 Stout Medical Group, L.P. Fixation device and method
US10940014B2 (en) 2008-11-12 2021-03-09 Stout Medical Group, L.P. Fixation device and method
US10285819B2 (en) 2008-11-12 2019-05-14 Stout Medical Group, L.P. Fixation device and method
USD754346S1 (en) 2009-03-02 2016-04-19 Nuvasive, Inc. Spinal fusion implant
USD797934S1 (en) 2009-03-02 2017-09-19 Nuvasive, Inc. Spinal fusion implant
US10413421B2 (en) 2009-03-12 2019-09-17 Nuvasive, Inc. Vertebral body replacement
US11458025B2 (en) 2009-03-12 2022-10-04 Nuvasive, Inc. Vertebral body replacement
US11712344B2 (en) 2009-03-12 2023-08-01 Nuvasive, Inc. Vertebral body replacement
US9387090B2 (en) 2009-03-12 2016-07-12 Nuvasive, Inc. Vertebral body replacement
US9636233B2 (en) 2009-03-12 2017-05-02 Nuvasive, Inc. Vertebral body replacement
US10390960B2 (en) 2009-03-12 2019-08-27 Nuvasive, Inc. Vertebral body replacement
US9687357B2 (en) 2009-03-12 2017-06-27 Nuvasive, Inc. Vertebral body replacement
US9522068B2 (en) 2009-03-13 2016-12-20 The University Of Toledo Minimally invasive collapsible cage
EP2408382A1 (en) * 2009-03-13 2012-01-25 The University of Toledo Minimally invasive collapsible cage
US9901460B2 (en) 2009-03-13 2018-02-27 The University Of Toledo Minimally invasive collapsible cage
EP2408382A4 (en) * 2009-03-13 2013-06-19 Univ Toledo Minimally invasive collapsible cage
US11612491B2 (en) 2009-03-30 2023-03-28 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US9757246B1 (en) 2009-04-16 2017-09-12 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US11246713B2 (en) 2009-04-16 2022-02-15 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US9192482B1 (en) 2009-04-16 2015-11-24 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US10426627B2 (en) 2009-04-16 2019-10-01 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US11647999B1 (en) 2009-04-16 2023-05-16 Nuvasive, Inc. Method and apparatus for performing spine surgery
US9351845B1 (en) 2009-04-16 2016-05-31 Nuvasive, Inc. Method and apparatus for performing spine surgery
US10327750B1 (en) 2009-04-16 2019-06-25 Nuvasive, Inc. Method and apparatus for performing spine surgery
US8920500B1 (en) 2009-04-16 2014-12-30 Nuvasive, Inc. Methods and apparatus for performing spine surgery
WO2011028396A3 (en) * 2009-08-26 2011-06-30 Synthes Usa, Llc Stabilizing bone fixation element
US9844403B2 (en) 2009-08-26 2017-12-19 DePuy Synthes Products, Inc. Stabilizing bone fixation element
US10195049B2 (en) 2009-11-05 2019-02-05 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US10792166B2 (en) 2009-11-05 2020-10-06 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US11712349B2 (en) 2009-11-05 2023-08-01 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US9931224B2 (en) 2009-11-05 2018-04-03 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US11607321B2 (en) 2009-12-10 2023-03-21 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
US8845733B2 (en) 2010-06-24 2014-09-30 DePuy Synthes Products, LLC Lateral spondylolisthesis reduction cage
US9801640B2 (en) 2010-06-24 2017-10-31 DePuy Synthes Products, Inc. Lateral spondylolisthesis reduction cage
US11911287B2 (en) 2010-06-24 2024-02-27 DePuy Synthes Products, Inc. Lateral spondylolisthesis reduction cage
US11872139B2 (en) 2010-06-24 2024-01-16 DePuy Synthes Products, Inc. Enhanced cage insertion assembly
US9763678B2 (en) 2010-06-24 2017-09-19 DePuy Synthes Products, Inc. Multi-segment lateral cage adapted to flex substantially in the coronal plane
US10646350B2 (en) 2010-06-24 2020-05-12 DePuy Synthes Products, Inc. Multi-segment lateral cages adapted to flex substantially in the coronal plane
US9801639B2 (en) 2010-06-24 2017-10-31 DePuy Synthes Products, Inc. Lateral spondylolisthesis reduction cage
US10588754B2 (en) 2010-06-24 2020-03-17 DePuy Snythes Products, Inc. Lateral spondylolisthesis reduction cage and instruments and methods for non-parallel disc space preparation
US9907560B2 (en) 2010-06-24 2018-03-06 DePuy Synthes Products, Inc. Flexible vertebral body shavers
US9592063B2 (en) 2010-06-24 2017-03-14 DePuy Synthes Products, Inc. Universal trial for lateral cages
US10405989B2 (en) 2010-06-24 2019-09-10 DePuy Synthes Products, Inc. Lateral spondylolisthesis reduction cage
US9282979B2 (en) 2010-06-24 2016-03-15 DePuy Synthes Products, Inc. Instruments and methods for non-parallel disc space preparation
US11654033B2 (en) 2010-06-29 2023-05-23 DePuy Synthes Products, Inc. Distractible intervertebral implant
US11452607B2 (en) 2010-10-11 2022-09-27 DePuy Synthes Products, Inc. Expandable interspinous process spacer implant
US9149286B1 (en) 2010-11-12 2015-10-06 Flexmedex, LLC Guidance tool and method for use
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
US10485672B2 (en) 2011-03-20 2019-11-26 Nuvasive, Inc. Vertebral body replacement and insertion methods
US11389301B2 (en) 2011-03-20 2022-07-19 Nuvasive, Inc. Vertebral body replacement and insertion methods
US11369490B2 (en) 2011-03-22 2022-06-28 DePuy Synthes Products, Inc. Universal trial for lateral cages
US9050112B2 (en) 2011-08-23 2015-06-09 Flexmedex, LLC Tissue removal device and method
US9655744B1 (en) 2011-10-31 2017-05-23 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9226764B2 (en) 2012-03-06 2016-01-05 DePuy Synthes Products, Inc. Conformable soft tissue removal instruments
US9445918B1 (en) 2012-10-22 2016-09-20 Nuvasive, Inc. Expandable spinal fusion implants and related instruments and methods
US10350084B1 (en) 2012-10-22 2019-07-16 Nuvasive, Inc. Expandable spinal fusion implant, related instruments and methods
US11399954B2 (en) 2012-10-22 2022-08-02 Nuvasive, Inc. Expandable spinal fusion implant, related instruments and methods
US10022245B2 (en) 2012-12-17 2018-07-17 DePuy Synthes Products, Inc. Polyaxial articulating instrument
US11850164B2 (en) 2013-03-07 2023-12-26 DePuy Synthes Products, Inc. Intervertebral implant
US11497619B2 (en) 2013-03-07 2022-11-15 DePuy Synthes Products, Inc. Intervertebral implant
US11679000B2 (en) 2013-05-22 2023-06-20 Nuvasive, Inc. Expandable fusion implant and related methods
US11426290B2 (en) 2015-03-06 2022-08-30 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
RU2592606C1 (en) * 2015-04-28 2016-07-27 федеральное государственное автономное образовательное учреждение высшего образования "Самарский государственный аэрокосмический университет имени академика С.П. Королева (национальный исследовательский университет)" (СГАУ) Vertebral implant
US11234833B2 (en) 2015-05-12 2022-02-01 Nuvasive, Inc. Expandable lordosis intervertebral implants
US11690730B2 (en) 2015-12-30 2023-07-04 Nuvasive, Inc. Lordotic expandable fusion implant
US10973650B2 (en) 2015-12-30 2021-04-13 Nuvasive, Inc. Lordotic expandable fusion implant
US11510788B2 (en) 2016-06-28 2022-11-29 Eit Emerging Implant Technologies Gmbh Expandable, angularly adjustable intervertebral cages
US11596522B2 (en) 2016-06-28 2023-03-07 Eit Emerging Implant Technologies Gmbh Expandable and angularly adjustable intervertebral cages with articulating joint
US11596523B2 (en) 2016-06-28 2023-03-07 Eit Emerging Implant Technologies Gmbh Expandable and angularly adjustable articulating intervertebral cages
US11446155B2 (en) 2017-05-08 2022-09-20 Medos International Sarl Expandable cage
US11344424B2 (en) 2017-06-14 2022-05-31 Medos International Sarl Expandable intervertebral implant and related methods
US10966843B2 (en) 2017-07-18 2021-04-06 DePuy Synthes Products, Inc. Implant inserters and related methods
US11045331B2 (en) 2017-08-14 2021-06-29 DePuy Synthes Products, Inc. Intervertebral implant inserters and related methods
US11690734B2 (en) 2017-08-14 2023-07-04 DePuy Synthes Products, Inc. Intervertebral implant inserters and related methods
US11273047B2 (en) 2017-12-18 2022-03-15 Nuvasive, Inc. Expandable implant device
US11020239B2 (en) 2018-02-22 2021-06-01 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US10856997B2 (en) 2018-02-22 2020-12-08 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US11752005B2 (en) 2018-02-22 2023-09-12 Warsaw Orthopedic, Inc. Expandable spinal implant system and method of using same
US11446156B2 (en) 2018-10-25 2022-09-20 Medos International Sarl Expandable intervertebral implant, inserter instrument, and related methods
US11806245B2 (en) 2020-03-06 2023-11-07 Eit Emerging Implant Technologies Gmbh Expandable intervertebral implant
US11638653B2 (en) 2020-11-05 2023-05-02 Warsaw Orthopedic, Inc. Surgery instruments with a movable handle
US11376134B1 (en) 2020-11-05 2022-07-05 Warsaw Orthopedic, Inc. Dual expanding spinal implant, system, and method of use
US11617658B2 (en) 2020-11-05 2023-04-04 Warsaw Orthopedic, Inc. Expandable inter-body device, system and method
US11564724B2 (en) 2020-11-05 2023-01-31 Warsaw Orthopedic, Inc. Expandable inter-body device, system and method
US11285014B1 (en) 2020-11-05 2022-03-29 Warsaw Orthopedic, Inc. Expandable inter-body device, system, and method
US11517443B2 (en) 2020-11-05 2022-12-06 Warsaw Orthopedic, Inc. Dual wedge expandable implant, system and method of use
US11833059B2 (en) 2020-11-05 2023-12-05 Warsaw Orthopedic, Inc. Expandable inter-body device, expandable plate system, and associated methods
US11850160B2 (en) 2021-03-26 2023-12-26 Medos International Sarl Expandable lordotic intervertebral fusion cage
US11752009B2 (en) 2021-04-06 2023-09-12 Medos International Sarl Expandable intervertebral fusion cage
US11291554B1 (en) 2021-05-03 2022-04-05 Medtronic, Inc. Unibody dual expanding interbody implant
US11395743B1 (en) 2021-05-04 2022-07-26 Warsaw Orthopedic, Inc. Externally driven expandable interbody and related methods
US11612499B2 (en) 2021-06-24 2023-03-28 Warsaw Orthopedic, Inc. Expandable interbody implant
US11730608B2 (en) 2021-07-13 2023-08-22 Warsaw Orthopedic, Inc. Monoblock expandable interbody implant
US11850163B2 (en) 2022-02-01 2023-12-26 Warsaw Orthopedic, Inc. Interbody implant with adjusting shims

Also Published As

Publication number Publication date
DE69209494D1 (en) 1996-05-02
AU1454192A (en) 1992-09-15
EP0571555A1 (en) 1993-12-01
DE69209494T2 (en) 1996-10-31
JPH06504704A (en) 1994-06-02
JP3390431B2 (en) 2003-03-24
CA2104391C (en) 2006-01-24
US5693100A (en) 1997-12-02
CA2104391A1 (en) 1992-08-23
EP0571555B1 (en) 1996-03-27

Similar Documents

Publication Publication Date Title
US5390683A (en) Spinal implantation methods utilizing a middle expandable implant
EP0571555B1 (en) Middle expandable intervertebral disk implant
US11759331B2 (en) Stabilized expandable intervertebral spacer
US11896493B2 (en) Expandable intervertebral spacer
US5171278A (en) Middle expandable intervertebral disk implants
US5653761A (en) Method of lumbar intervertebral disk stabilization
US8414649B1 (en) Artificial spinal disk
JP3635236B2 (en) Osteogenic fusion device
US7544208B1 (en) Adjustable corpectomy apparatus
US8303660B1 (en) Inter-vertebral disc prosthesis with variable rotational stop and methods of use
US20080243255A1 (en) Radially expandable spinal interbody device and implantation tool
US20170165082A1 (en) Stabilized expandable intervertebral spacer
US11259938B2 (en) Stabilized intervertebral spacer
KR20010075238A (en) Box cage for intervertebral body fusion
WO2000004851A1 (en) Threaded cylindrical multidiscoid single or multiple array disc prosthesis
JPS63145650A (en) Vertebra implant
JP2002524142A (en) Threaded cylindrical disc prosthesis
US20080249627A1 (en) Prosthetic Disc Device and Method for Intervertebral Disc Replacement

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AT AU BB BG BR CA CH DE DK ES FI GB HU JP KP KR LK LU MG MW NL NO PL RO RU SD SE US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE BF BJ CF CG CH CI CM DE DK ES FR GA GB GN GR IT LU MC ML MR NL SE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGES 1/4-4/4,DRAWINGS,REPLACED BY NEW PAGES 1/4-4/4;DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2104391

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 08107750

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 1992907757

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1992907757

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWG Wipo information: grant in national office

Ref document number: 1992907757

Country of ref document: EP