WO1993023010A1 - Ophthalmic compositions containing a cyclosporin - Google Patents
Ophthalmic compositions containing a cyclosporin Download PDFInfo
- Publication number
- WO1993023010A1 WO1993023010A1 PCT/EP1993/001123 EP9301123W WO9323010A1 WO 1993023010 A1 WO1993023010 A1 WO 1993023010A1 EP 9301123 W EP9301123 W EP 9301123W WO 9323010 A1 WO9323010 A1 WO 9323010A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cyclosporin
- eye
- ophthalmic composition
- composition according
- ophthalmic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69307505T DE69307505T2 (en) | 1992-05-13 | 1993-05-07 | OPTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN |
EP93909919A EP0642332B1 (en) | 1992-05-13 | 1993-05-07 | Ophthalmic compositions containing a cyclosporin |
JP51984293A JP3631490B2 (en) | 1992-05-13 | 1993-05-07 | Cyclosporine-containing ophthalmic composition |
GR970400664T GR3022990T3 (en) | 1992-05-13 | 1997-04-01 | Ophthalmic compositions containing a cyclosporin. |
HK98103406A HK1004520A1 (en) | 1992-05-13 | 1998-04-23 | Ophthalmic compositions containing a cyclosporin |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929210226A GB9210226D0 (en) | 1992-05-13 | 1992-05-13 | Pharmaceutical compositions |
GB9210226.8 | 1992-05-13 | ||
GB9224367.4 | 1992-11-20 | ||
GB929224367A GB9224367D0 (en) | 1992-11-20 | 1992-11-20 | Organic compounds |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/767,610 Continuation US5951971A (en) | 1992-05-13 | 1996-12-17 | Ophthalmic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1993023010A1 true WO1993023010A1 (en) | 1993-11-25 |
Family
ID=26300871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1993/001123 WO1993023010A1 (en) | 1992-05-13 | 1993-05-07 | Ophthalmic compositions containing a cyclosporin |
Country Status (14)
Country | Link |
---|---|
US (2) | US5951971A (en) |
EP (1) | EP0642332B1 (en) |
JP (2) | JP3631490B2 (en) |
KR (1) | KR100344083B1 (en) |
CN (1) | CN1074932C (en) |
AT (1) | ATE147619T1 (en) |
DE (1) | DE69307505T2 (en) |
DK (1) | DK0642332T3 (en) |
ES (1) | ES2098739T3 (en) |
GR (1) | GR3022990T3 (en) |
HK (1) | HK1004520A1 (en) |
SG (1) | SG45449A1 (en) |
TW (1) | TW279801B (en) |
WO (1) | WO1993023010A1 (en) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
EP0868909A2 (en) * | 1997-03-14 | 1998-10-07 | Arturo Jimenez-Bayardo | Ophthalmic carrier solution |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
EP1142566A1 (en) * | 2000-04-07 | 2001-10-10 | Laboratoire Medidom S.A. | Compositions for ophtalmic use containing cyclosporin, hyaluronic acid and polysorbate |
WO2004096261A1 (en) * | 2003-05-02 | 2004-11-11 | Arturo Jimenez Bayardo | Method of preparing an aqueous solution of cyclosporin-a and resulting aqueous solution |
WO2005049061A2 (en) * | 2003-11-20 | 2005-06-02 | Novo Nordisk A/S | Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices |
EP1889620A1 (en) * | 2005-06-09 | 2008-02-20 | Santen Pharmaceutical Co., Ltd | Eye drop containing roflumilast |
US8114959B2 (en) | 2003-06-03 | 2012-02-14 | Novo Nordisk A/S | Stabilized pharmaceutical peptide compositions |
WO2013140071A1 (en) * | 2012-03-22 | 2013-09-26 | Laboratoires Thea | Cyclosporin a-based aqueous ophthalmic solution |
US8614181B2 (en) | 2003-06-03 | 2013-12-24 | Novo Nordisk A/S | Stabilized pharmaceutical peptide compositions |
US8710181B2 (en) | 2004-08-31 | 2014-04-29 | Novo Nordisk A/S | Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins |
US8748376B2 (en) | 2004-11-12 | 2014-06-10 | Novo Nordisk A/S | Stable formulations of peptides |
US8846618B2 (en) | 2001-06-28 | 2014-09-30 | Novo Nordisk A/S | Stable formulation of modified GLP-1 |
KR20150100763A (en) * | 2012-12-19 | 2015-09-02 | 에스에이알코드 바이오사이언스 인코포레이티드 | Lfa-1 inhibitor formulations |
WO2016011449A1 (en) * | 2014-07-18 | 2016-01-21 | Allergan, Inc. | Suspension compositions of cyclosporin a for subconjunctival and periocular injection |
WO2016012912A1 (en) | 2014-07-25 | 2016-01-28 | Imuneks Farma Ilac Sanayi Ve Ticaret A.S. | Stable preservative free ophthalmic formulations of opioid antagonists |
EP3329940A4 (en) * | 2015-07-29 | 2019-01-02 | Kukje Pharm. Ind. Co., Ltd | Non-irritant ophthalmic composition containing cyclosporin, and convenient preparation method |
CN109906085A (en) * | 2016-09-23 | 2019-06-18 | 诺瓦利克有限责任公司 | Ophthalmic composition containing cyclosporine |
US11318191B2 (en) | 2020-02-18 | 2022-05-03 | Novo Nordisk A/S | GLP-1 compositions and uses thereof |
US11752198B2 (en) | 2017-08-24 | 2023-09-12 | Novo Nordisk A/S | GLP-1 compositions and uses thereof |
Families Citing this family (47)
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---|---|---|---|---|
ATE147619T1 (en) * | 1992-05-13 | 1997-02-15 | Sandoz Ag | OPTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN |
DE29824679U1 (en) | 1997-01-30 | 2002-03-28 | Novartis Ag | Pharmaceutical compositions |
ATE273704T1 (en) | 1999-06-03 | 2004-09-15 | Maxim Pharm Inc | OPHTHALMIC HISTAMINE-CONTAINING COMPOSITIONS AND USE THEREOF |
JP4880808B2 (en) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | Artificial tear-type eye drop composition |
US20030165545A1 (en) * | 2002-01-30 | 2003-09-04 | Allergan, Inc. | Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US7241674B2 (en) * | 2004-05-13 | 2007-07-10 | Taiwan Semiconductor Manufacturing Co., Ltd. | Method of forming silicided gate structure |
US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
CN101171000A (en) * | 2005-04-12 | 2008-04-30 | 依兰药物国际有限公司 | Nanoparticulate and controlled release compositions comprising cyclosporine |
US7202209B2 (en) | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
US20070015693A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US20070015691A1 (en) | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US7297679B2 (en) * | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
US7276476B2 (en) * | 2005-07-13 | 2007-10-02 | Allergan, Inc. | Cyclosporin compositions |
US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
US7745400B2 (en) * | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
EP1937290A1 (en) * | 2005-10-14 | 2008-07-02 | Allergan, Inc. | Prevention and treatment of drug-associated ocular side effects with a cyclosporin |
JP2009514969A (en) * | 2005-11-09 | 2009-04-09 | コンビナトアールエックス インコーポレーティッド | Methods, compositions, and kits for treating medical conditions |
US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
US20080146497A1 (en) * | 2006-07-25 | 2008-06-19 | Graham Richard S | Cyclosporin Compositions |
AU2016203191B2 (en) * | 2006-07-25 | 2018-03-01 | Allergan, Inc. | Cyclosporin compositions |
CN101896160A (en) * | 2006-10-17 | 2010-11-24 | 阿勒根公司 | Cyclosporin compositions |
DE202007008971U1 (en) | 2007-06-27 | 2008-11-06 | Weber, Erhard, Dr. | Foam spacers for filling mattress cores, upholstery and pillows |
US20090286718A1 (en) * | 2008-01-04 | 2009-11-19 | Sirion Therapeutics, Inc. | Stable Aqueous Cyclosporin Compositions |
JP5288970B2 (en) * | 2008-09-26 | 2013-09-11 | シスメックス株式会社 | Method for measuring mean red blood cell volume using a reagent for diluting blood samples |
US20100279951A1 (en) * | 2009-05-01 | 2010-11-04 | Aileen Morgan | Method of treating allergic conjunctivitis with cyclosporin compositions |
US9119827B2 (en) * | 2009-06-30 | 2015-09-01 | Lion Corporation | Ophthalmic composition |
US8501796B2 (en) | 2010-09-16 | 2013-08-06 | Allergan, Inc. | Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure |
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US9018202B2 (en) | 2010-12-03 | 2015-04-28 | Allergan, Inc. | Methods for treating diseases of the retina |
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US9095576B2 (en) | 2011-11-21 | 2015-08-04 | Allergan, Inc. | Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole derivatives for treating retinal diseases |
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KR20180028992A (en) * | 2015-05-29 | 2018-03-19 | 오쿨리스 이에이치에프. | Formation of Cyclosporin A / Cyclodextrin Nanoparticles |
JP7072517B2 (en) * | 2016-02-29 | 2022-05-20 | サン ファーマ グローバル エフゼットイー | Topical cyclosporine-containing preparations and their use |
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Citations (5)
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- 1993-05-07 JP JP51984293A patent/JP3631490B2/en not_active Expired - Lifetime
- 1993-05-07 SG SG1996008974A patent/SG45449A1/en unknown
- 1993-05-07 DK DK93909919.8T patent/DK0642332T3/en active
- 1993-05-07 EP EP93909919A patent/EP0642332B1/en not_active Expired - Lifetime
- 1993-05-07 DE DE69307505T patent/DE69307505T2/en not_active Expired - Lifetime
- 1993-05-07 ES ES93909919T patent/ES2098739T3/en not_active Expired - Lifetime
- 1993-05-12 CN CN93107203A patent/CN1074932C/en not_active Expired - Lifetime
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1994
- 1994-11-10 KR KR1019940704017A patent/KR100344083B1/en not_active IP Right Cessation
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1996
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1997
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1998
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2001
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US6254885B1 (en) | 1995-08-25 | 2001-07-03 | Sangstat Medical Corporation | Oral cyclosphorin formulations |
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Also Published As
Publication number | Publication date |
---|---|
SG45449A1 (en) | 1998-01-16 |
TW279801B (en) | 1996-07-01 |
US5951971A (en) | 1999-09-14 |
GR3022990T3 (en) | 1997-07-30 |
JPH07506579A (en) | 1995-07-20 |
JP3631490B2 (en) | 2005-03-23 |
CN1074932C (en) | 2001-11-21 |
CN1084079A (en) | 1994-03-23 |
DE69307505T2 (en) | 1997-07-24 |
US20020045601A1 (en) | 2002-04-18 |
ATE147619T1 (en) | 1997-02-15 |
DK0642332T3 (en) | 1997-06-16 |
DE69307505D1 (en) | 1997-02-27 |
JP2004346085A (en) | 2004-12-09 |
KR100344083B1 (en) | 2002-11-23 |
ES2098739T3 (en) | 1997-05-01 |
EP0642332B1 (en) | 1997-01-15 |
KR950701515A (en) | 1995-04-28 |
EP0642332A1 (en) | 1995-03-15 |
US6582718B2 (en) | 2003-06-24 |
HK1004520A1 (en) | 1998-11-27 |
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