WO1994011051A1 - Large diameter vasoocclusion coil - Google Patents
Large diameter vasoocclusion coil Download PDFInfo
- Publication number
- WO1994011051A1 WO1994011051A1 PCT/US1993/000882 US9300882W WO9411051A1 WO 1994011051 A1 WO1994011051 A1 WO 1994011051A1 US 9300882 W US9300882 W US 9300882W WO 9411051 A1 WO9411051 A1 WO 9411051A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- coil
- helical coil
- helical
- vessel
- shaped structure
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
Definitions
- This invention is in the general field of surgical instruments. More particularly, it relates to a vasoocclusion device that can be used in cardiovascular and endovascular procedures.
- Vasoocclusion devices are surgical implements that are placed within vessels, typically via a catheter, to block the flow of blood through the vessel.
- Vasoocclusive coils have been used to occlude vessels in small-diameter, difficult to reach sites.
- United States Patent No. 4,994,069 provides a vasoocclusive wire that is guided to a vessel that has a diameter of between 0.5 and 6 mm.
- the patent describes a flexible vasoocclusive wire that is designed to occlude a vessel when the wire is released into the vessel.
- the diameter of the coiled wire is between about 10-30 mils, the wire itself has an outside diameter of between about 2-6 mils and there are about 4-8 helical windings.
- the wire has a preferred length of about 3-6 cm, and for a vessel that is 2-6 mm, the wire has a preferred length of about 5-10 cm.
- the device is a vasoocclusive coil that assumes a linear helical
- the stretched condition is used in placing the coil at the desired site and the coil assumes its relaxed configuration once the device is so placed.
- the vasoocclusive device is a helical coil having a multiplicity of windings between a first and second end wherein the primary coil diameter is between about 0.25 and 1.5 mm and the diameter of the vessel to be occluded is between about 1.0 and 3.0 cm. Once relaxed, the coil may assume a secondary coil diameter approaching that of the selected vessel.
- Figs. 1 to 9 are fragmentary elevational views (not to scale) of embodiments of the helical coil of the invention.
- Fig. 1 depicts one embodiment, generally designated 10, of the helical vasoocclusive coil of the invention.
- the helical coil 10 will typically be made of a radiopaque material such as platinum, tungsten, gold, stainless steel, or of alloys such as tungsten and platinum.
- a tungsten-platinum alloy is preferred because of its strength and toughness.
- the material desirably is radiopaque and the diameter of the wire will usually be in the range of 0.05 to 0.25 mm.
- the coil has a
- the axial length of the coil will usually be in the range of 0.2 to 100 cm, more usually 0.2 to 40 cm and the diameter of the coil will normally be 0.25 and 1.5 mm, more usually 0.5 to 1.0 mm.
- the coil will typically have about 40 to 200 windings per cm, more typically about 50 to 130 windings per cm.
- the steps in the construction of the vasoocclusion coils of this invention are shown in Figs. 1-3.
- the coil itself may be formed by wrappings of windings of a fine radiopaque wire thread, preferably 5 to 8 mil (0.13 to 0.20 mm) platinum, tungsten, gold, stainless steel or alloy thread which is available, for example, from California Fine Wire Company (Grover City, CA).
- the windings are preferably made by wrapping the thread on a spinning mandrel, according to known coilmanufacturing methods.
- the wire advance on the mandrel is adjusted to produce a single-layer coil with a minimum helical pitch, i.e., in which the windings are closely packed.
- the mandrel has a diameter of between about 0.10 and 1.0 mm yielding a coil whose outer
- the soft, flexible coil produced on the mandrel is cut to a desired length of between about 4 and 100 cm after removal from the mandrel.
- the coiled wire may then be wound on a larger diameter mandrel to form a helical winding as shown in Fig. 2 whose helix diameter, indicated at 14, is
- the diameter of this secondary helical winding is preferably 1-3 cm, respectively. It can be appreciated from the above-mentioned wire lengths and winding
- wires typically will contain 1-20 helical windings, more typically 4-8 helical windings as illustrated in Fig. 2.
- the coil may further be preformed to contain irregularities in the helical winding, such that the coil adopts a folded, convoluted conformation in a relaxed condition as illustrated in Fig. 3.
- the irregularities in this embodiment are such as to offset the helical axis (indicated by arrows in the figure) of each winding by 20-40 degrees.
- the irregularities are preferably made by deforming, as by twisting, the coil in the region of desired bends with the coil on the helical winding mandrel.
- the coil may treated by heating at about 800°F for about 24 hours for memory retention after it is shaped.
- the combination of the helical winding and the irregularities in the winding cause the coil to form a randomly shaped, substantially space-filling mass when released into a vessel, as will be illustrated below.
- the memory in the coil is effective to return the coil from a stretched, linear condition in which it is advanced through a catheter to a randomly oriented, space-filling relaxed condition as the coil is released from the catheter.
- the coil just described may be thought of as having a primary structure formed by the wire wrapping making up. the coil, a secondary structure formed by the helical winding of the coil, and a tertiary structure formed by the irregularities in the winding of the coil. It will be appreciated that the random shape of the coil in its relaxed condition can be achieved by other, related secondary structures in the coil, such as a series of arcs which are interrupted at intervals by bends which orient the arcs in different directions.
- the primary helical coil may be wound around a series of mandrels that are held in some uniform configuration to yield the offset helical shape shown in Fig. 3. Multiple coils may be formed in this way and thereafter the coils may be cut to form individual vasoocclusive coils.
- the coil is preferably supplied in prepackaged form in a sterile cannula.
- the cannula straightens the coil during shipment such that it can be placed within a catheter lumen for delivery to the targeted vessel.
- a guidewire is inserted such that a catheter can be guided to the targeted vessel.
- the guidewire is removed and the coil-containing cannula is placed into engagement with the proximal end of the catheter.
- the coil is then transferred from the cannula lumen into the catheter lumen by exerting force on the proximal end of the coil.
- the coil is advanced through the catheter to the tissue of interest by means a guidewire or coil pusher that pushes against the proximal end of the coil.
- water may be injected into the catheter to force the coil through the catheter lumen.
- the location of the coil may be visualized due to the radiopacity of the helical coil. Once at the site, the coil is plunged from the distal end of the catheter into the targeted vessel.
- the coil is supplied in a cannula which is adapted to engage the proximal end of a guidewire. Once the guidewire and catheter are in place, the coil-containing cannula is placed into engagement with the proximal end of the guidewire and the coil is transferred from the cannula lumen onto the guidewire by exerting force on the
- the coil is delivered to the targeted site by being pushed with a guidewire, coil pusher or by means of hydraulic injection as described above.
- Figs, 1 to 9 show variants of the invention, but for simplicity of explanation, show the shape when the coil is in the catheter lumen (Figs. 1 and 7) and after release of the coil at the targeted site (Figs. 2 to 6, 8 and 9).
- Fig. 2 shows a partial side view of the helical coil 10 in its relaxed configuration.
- the coil 10 will be placed inside the catheter lumen in its linear stretched form (as shown in Fig. 1) until discharged from the end of the catheter at which time the configuration shown in Fig. 2 will be assumed.
- Fig. 3 shows another embodiment of a vasoocclusive coil of the invention after it has been released from the end of the catheter.
- the coil loops back upon itself to form a secondary coil having a tertiary configuration that may substantially fill the vessel to be occluded. Irregularities in the coil windings allow formation of the folded convoluted
- Figs. 4, 5, and 6 each illustrate a different aspect of the invention.
- Fig. 3 shows a helical coil that forms a tertiary shape that is circular
- Figs. 4-6 show additional coils whose tertiary structures are also useful in the invention.
- Fig. 4 shows a cloverleafshaped vasoocclusive coil
- Fig. 5 shows a figure-8-shaped
- Fig. 6 shows a C-shaped vasoocclusive coil.
- the tertiary structures are the relaxed configurations of the coils after release into the vessel.
- the devices are introduced as helical coils as shown in Fig. 1 and then assume the shapes shown.
- the maximum helical coil diameters of the coils shown as 20, 22 and 24 are
- Figures 7 and 8 show a vasoocclusive coil such as is described above, but in which irregularities in the helical winding are produced by flattening the wire coil in different directions. This may be accomplished by flattening or squeezing the linear coil 30 in a number of places 32 along the winding at various angles (if so desired) such as is shown in Fig. 7.
- the coil so formed will have the general appearance shown in Fig. 7 when in its linear configuration.
- the coil will be in its linear configuration as shown in Fig. 7 during its introduction into the vessel, but will assume the shape shown in Fig. 8 when in its relaxed configuration.
- Fig. 9 shows a coil having a primary coil structure as described above, with a helical winding 40 having at least one helical turn whose diameter 42 is the size of the vessel to be occluded.
- the irregularities in the helical winding take the form of continually changing helical diameters forming spirals which are dimensioned to span the cross-sectional area of the vessel.
- the coils of the present invention therefore are useful for occluding vessels in the range of about 1 to 3 cm.
- Such applications include the occlusion of fistulas of the pulmonary vasculature in the lungs, trauma in the periphery, arteriovenous malformations, heart anomalies and aneurysms.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002144725A CA2144725C (en) | 1992-11-19 | 1993-02-03 | Large diameter vasoocclusion coil |
EP93904799A EP0743866A1 (en) | 1992-11-19 | 1993-02-03 | Large diameter vasoocclusion coil |
AU36037/93A AU681073B2 (en) | 1992-11-19 | 1993-02-03 | Large diameter vasoocclusion coil |
JP6512040A JPH08500273A (en) | 1992-11-19 | 1993-02-03 | Large diameter vasoocclusive coil |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97823092A | 1992-11-19 | 1992-11-19 | |
US07/978,230 | 1992-11-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1994011051A1 true WO1994011051A1 (en) | 1994-05-26 |
Family
ID=25525882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1993/000882 WO1994011051A1 (en) | 1992-11-19 | 1993-02-03 | Large diameter vasoocclusion coil |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0743866A1 (en) |
JP (1) | JPH08500273A (en) |
AU (1) | AU681073B2 (en) |
CA (1) | CA2144725C (en) |
IL (1) | IL104870A0 (en) |
WO (1) | WO1994011051A1 (en) |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5690671A (en) * | 1994-12-13 | 1997-11-25 | Micro Interventional Systems, Inc. | Embolic elements and methods and apparatus for their delivery |
US5709224A (en) * | 1995-06-07 | 1998-01-20 | Radiotherapeutics Corporation | Method and device for permanent vessel occlusion |
US6145505A (en) * | 1995-06-07 | 2000-11-14 | Conceptus, Inc. | Electrically affixed transcervical fallopian tube occlusion devices |
US6270495B1 (en) | 1996-02-22 | 2001-08-07 | Radiotherapeutics Corporation | Method and device for enhancing vessel occlusion |
US6348041B1 (en) | 1999-03-29 | 2002-02-19 | Cook Incorporated | Guidewire |
US6526979B1 (en) | 1995-06-07 | 2003-03-04 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
US6551340B1 (en) | 1998-10-09 | 2003-04-22 | Board Of Regents The University Of Texas System | Vasoocclusion coil device having a core therein |
WO2003039376A1 (en) * | 2001-11-07 | 2003-05-15 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US6589227B2 (en) | 2000-01-28 | 2003-07-08 | William Cook Europe Aps | Endovascular medical device with plurality of wires |
US6605101B1 (en) | 2000-09-26 | 2003-08-12 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US6709667B1 (en) | 1999-08-23 | 2004-03-23 | Conceptus, Inc. | Deployment actuation system for intrafallopian contraception |
US6763833B1 (en) | 1999-08-23 | 2004-07-20 | Conceptus, Inc. | Insertion/deployment catheter system for intrafallopian contraception |
US6776788B1 (en) | 1996-09-03 | 2004-08-17 | William Cook, Europe A/S | Embolization device for positioning in a blood vessel |
EP1554983A1 (en) * | 2004-01-16 | 2005-07-20 | Medico's Hirata Inc. | Bioabsorbable vasoocclusive coil |
US7029486B2 (en) | 2000-09-26 | 2006-04-18 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US7033374B2 (en) | 2000-09-26 | 2006-04-25 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US8864790B2 (en) | 2006-04-17 | 2014-10-21 | Covidien Lp | System and method for mechanically positioning intravascular implants |
US9011480B2 (en) | 2012-01-20 | 2015-04-21 | Covidien Lp | Aneurysm treatment coils |
US9050095B2 (en) | 2004-09-22 | 2015-06-09 | Covidien Lp | Medical implant |
US9198665B2 (en) | 2004-09-22 | 2015-12-01 | Covidien Lp | Micro-spiral implantation device |
CN105286937A (en) * | 2001-11-07 | 2016-02-03 | 微温森公司 | Vascular obstruction device |
US9289215B2 (en) | 2007-03-13 | 2016-03-22 | Covidien Lp | Implant including a coil and a stretch-resistant member |
US9579104B2 (en) | 2011-11-30 | 2017-02-28 | Covidien Lp | Positioning and detaching implants |
US9636118B2 (en) | 2014-02-27 | 2017-05-02 | Incumedx, Inc. | Embolic framing microcoils |
CN106659505A (en) * | 2014-07-25 | 2017-05-10 | 因库麦迪斯有限公司 | Covered embolic coils |
US9687245B2 (en) | 2012-03-23 | 2017-06-27 | Covidien Lp | Occlusive devices and methods of use |
US9713475B2 (en) | 2014-04-18 | 2017-07-25 | Covidien Lp | Embolic medical devices |
US10307168B2 (en) | 2015-08-07 | 2019-06-04 | Terumo Corporation | Complex coil and manufacturing techniques |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100015521A (en) | 2007-03-13 | 2010-02-12 | 마이크로 테라퓨틱스 인코포레이티드 | An implant, a mandrel, and a method of forming an implant |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994069A (en) * | 1988-11-02 | 1991-02-19 | Target Therapeutics | Vaso-occlusion coil and method |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD158084A1 (en) * | 1981-05-08 | 1982-12-29 | Joachim Heinke | CLOSURE BODY AND METHOD FOR ITS MANUFACTURE |
AU629658B2 (en) * | 1990-04-26 | 1992-10-08 | Semyon Gurevich | A catheter device for the insertion of a dilator prosthesis into tubular organs of humans or animals |
-
1993
- 1993-02-03 WO PCT/US1993/000882 patent/WO1994011051A1/en not_active Application Discontinuation
- 1993-02-03 EP EP93904799A patent/EP0743866A1/en not_active Withdrawn
- 1993-02-03 CA CA002144725A patent/CA2144725C/en not_active Expired - Fee Related
- 1993-02-03 AU AU36037/93A patent/AU681073B2/en not_active Ceased
- 1993-02-03 JP JP6512040A patent/JPH08500273A/en active Pending
- 1993-02-26 IL IL104870A patent/IL104870A0/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994069A (en) * | 1988-11-02 | 1991-02-19 | Target Therapeutics | Vaso-occlusion coil and method |
Cited By (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6165198A (en) * | 1994-12-13 | 2000-12-26 | Medtronic, Inc. | Embolic elements and methods and apparatus for their delivery |
US5690671A (en) * | 1994-12-13 | 1997-11-25 | Micro Interventional Systems, Inc. | Embolic elements and methods and apparatus for their delivery |
US6634361B1 (en) | 1995-06-07 | 2003-10-21 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
US6705323B1 (en) | 1995-06-07 | 2004-03-16 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
US6077261A (en) * | 1995-06-07 | 2000-06-20 | Radiotherapeutics Corporation | Device for permanent vessel occlusion |
US5709224A (en) * | 1995-06-07 | 1998-01-20 | Radiotherapeutics Corporation | Method and device for permanent vessel occlusion |
US6526979B1 (en) | 1995-06-07 | 2003-03-04 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
US7686020B2 (en) | 1995-06-07 | 2010-03-30 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and methods |
US6145505A (en) * | 1995-06-07 | 2000-11-14 | Conceptus, Inc. | Electrically affixed transcervical fallopian tube occlusion devices |
US8066007B2 (en) | 1995-06-07 | 2011-11-29 | Conceptus, Inc. | Contraceptive transcervical fallopian tube occlusion devices and their delivery |
US6270495B1 (en) | 1996-02-22 | 2001-08-07 | Radiotherapeutics Corporation | Method and device for enhancing vessel occlusion |
US6656173B1 (en) | 1996-02-22 | 2003-12-02 | Radio Therapeutics Corporation | Method and device for enhancing vessel occlusion |
US7892254B2 (en) | 1996-09-03 | 2011-02-22 | William Cook, Europe A/S | Embolization method for endovascular occlusion |
US6776788B1 (en) | 1996-09-03 | 2004-08-17 | William Cook, Europe A/S | Embolization device for positioning in a blood vessel |
US8733360B2 (en) | 1997-09-24 | 2014-05-27 | Bayer Essure Inc. | Occlusion devices and methods |
US6551340B1 (en) | 1998-10-09 | 2003-04-22 | Board Of Regents The University Of Texas System | Vasoocclusion coil device having a core therein |
US6348041B1 (en) | 1999-03-29 | 2002-02-19 | Cook Incorporated | Guidewire |
US7591268B2 (en) | 1999-08-23 | 2009-09-22 | Conceptus, Inc. | Deployment actuation system for intrafallopian contraception |
US7506650B2 (en) | 1999-08-23 | 2009-03-24 | Conceptus, Inc. | Deployment actuation system for intrafallopian contraception |
US9597224B2 (en) | 1999-08-23 | 2017-03-21 | Bayer Healthcare Llc | Deployment actuation system |
US7237552B2 (en) | 1999-08-23 | 2007-07-03 | Conceptus, Inc. | Insertion/deployment catheter system for intrafallopian contraception |
US6709667B1 (en) | 1999-08-23 | 2004-03-23 | Conceptus, Inc. | Deployment actuation system for intrafallopian contraception |
US6763833B1 (en) | 1999-08-23 | 2004-07-20 | Conceptus, Inc. | Insertion/deployment catheter system for intrafallopian contraception |
US7025758B2 (en) | 2000-01-28 | 2006-04-11 | William Cook Europe Aps | Endovascular medical device with plurality of wires |
US6589227B2 (en) | 2000-01-28 | 2003-07-08 | William Cook Europe Aps | Endovascular medical device with plurality of wires |
US7331974B2 (en) | 2000-09-26 | 2008-02-19 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US7033374B2 (en) | 2000-09-26 | 2006-04-25 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US7029486B2 (en) | 2000-09-26 | 2006-04-18 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US8323306B2 (en) | 2000-09-26 | 2012-12-04 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
US6605101B1 (en) | 2000-09-26 | 2003-08-12 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
WO2003039376A1 (en) * | 2001-11-07 | 2003-05-15 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
AU2002236676B2 (en) * | 2001-11-07 | 2008-02-28 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
CN105286937A (en) * | 2001-11-07 | 2016-02-03 | 微温森公司 | Vascular obstruction device |
EP2163212A1 (en) * | 2001-11-07 | 2010-03-17 | Microvention, Inc. | Microcoil vaso-occlusive device with multi-axis secondary configuration |
EP1554983A1 (en) * | 2004-01-16 | 2005-07-20 | Medico's Hirata Inc. | Bioabsorbable vasoocclusive coil |
US9050095B2 (en) | 2004-09-22 | 2015-06-09 | Covidien Lp | Medical implant |
US9198665B2 (en) | 2004-09-22 | 2015-12-01 | Covidien Lp | Micro-spiral implantation device |
US8864790B2 (en) | 2006-04-17 | 2014-10-21 | Covidien Lp | System and method for mechanically positioning intravascular implants |
US9289215B2 (en) | 2007-03-13 | 2016-03-22 | Covidien Lp | Implant including a coil and a stretch-resistant member |
US10335155B2 (en) | 2011-11-30 | 2019-07-02 | Covidien Lp | Positioning and detaching implants |
US9579104B2 (en) | 2011-11-30 | 2017-02-28 | Covidien Lp | Positioning and detaching implants |
US9011480B2 (en) | 2012-01-20 | 2015-04-21 | Covidien Lp | Aneurysm treatment coils |
US10893868B2 (en) | 2012-01-20 | 2021-01-19 | Covidien Lp | Aneurysm treatment coils |
US9687245B2 (en) | 2012-03-23 | 2017-06-27 | Covidien Lp | Occlusive devices and methods of use |
US9980734B2 (en) | 2014-02-27 | 2018-05-29 | Incumedx, Inc. | Embolic framing microcoils |
US10098645B2 (en) | 2014-02-27 | 2018-10-16 | Incumedx, Inc. | Embolic framing microcoils |
US9636118B2 (en) | 2014-02-27 | 2017-05-02 | Incumedx, Inc. | Embolic framing microcoils |
US9713475B2 (en) | 2014-04-18 | 2017-07-25 | Covidien Lp | Embolic medical devices |
CN106659505A (en) * | 2014-07-25 | 2017-05-10 | 因库麦迪斯有限公司 | Covered embolic coils |
US9987015B2 (en) | 2014-07-25 | 2018-06-05 | Incumedx, Inc. | Covered embolic coils |
CN106659505B (en) * | 2014-07-25 | 2019-07-02 | 因库麦迪斯有限公司 | Embolic coil with veil |
US10307168B2 (en) | 2015-08-07 | 2019-06-04 | Terumo Corporation | Complex coil and manufacturing techniques |
Also Published As
Publication number | Publication date |
---|---|
CA2144725A1 (en) | 1994-05-26 |
JPH08500273A (en) | 1996-01-16 |
CA2144725C (en) | 2000-06-06 |
AU681073B2 (en) | 1997-08-21 |
IL104870A0 (en) | 1993-06-10 |
AU3603793A (en) | 1994-06-08 |
EP0743866A4 (en) | 1996-07-26 |
EP0743866A1 (en) | 1996-11-27 |
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