WO1994013304A3 - Antacid composition and method of production - Google Patents

Antacid composition and method of production Download PDF

Info

Publication number
WO1994013304A3
WO1994013304A3 PCT/US1993/011720 US9311720W WO9413304A3 WO 1994013304 A3 WO1994013304 A3 WO 1994013304A3 US 9311720 W US9311720 W US 9311720W WO 9413304 A3 WO9413304 A3 WO 9413304A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
production
antacid composition
antacid
microns
Prior art date
Application number
PCT/US1993/011720
Other languages
French (fr)
Other versions
WO1994013304A2 (en
Inventor
Gary G Liversidge
Gregory L Mcintire
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Priority to AU63908/94A priority Critical patent/AU6390894A/en
Priority to KR1019950702371A priority patent/KR950703982A/en
Priority to JP6514256A priority patent/JPH08504442A/en
Priority to SK765-95A priority patent/SK76595A3/en
Priority to EP94911365A priority patent/EP0673253A1/en
Publication of WO1994013304A2 publication Critical patent/WO1994013304A2/en
Publication of WO1994013304A3 publication Critical patent/WO1994013304A3/en
Priority to NO952261A priority patent/NO952261D0/en
Priority to FI952859A priority patent/FI952859A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

An antacid composition comprising particles consisting essentially of an aluminum-based neutralizing agent having an average particle size of less than about 3 microns and a method for preparing the composition. These compositions exhibit significantly enhanced rate of neutralization over compositions containing larger particles and are useful in treating mammals for pain associated with stomach acid.
PCT/US1993/011720 1992-12-11 1993-12-03 Antacid composition and method of production WO1994013304A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU63908/94A AU6390894A (en) 1992-12-11 1993-12-03 Antacid composition and method of production
KR1019950702371A KR950703982A (en) 1992-12-11 1993-12-03 ANTACID COMPOSITON AND METHOD OF PRODUCTION
JP6514256A JPH08504442A (en) 1992-12-11 1993-12-03 Antacid composition and method for producing the same
SK765-95A SK76595A3 (en) 1992-12-11 1993-12-03 Antacid composition and method of production
EP94911365A EP0673253A1 (en) 1992-12-11 1993-12-03 Antacid composition and method of production
NO952261A NO952261D0 (en) 1992-12-11 1995-06-08 Antacidium Compounds and Methods of Preparation thereof
FI952859A FI952859A (en) 1992-12-11 1995-06-09 Antacid composition and its preparation process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98929692A 1992-12-11 1992-12-11
US989,296 1992-12-11

Publications (2)

Publication Number Publication Date
WO1994013304A2 WO1994013304A2 (en) 1994-06-23
WO1994013304A3 true WO1994013304A3 (en) 1994-09-01

Family

ID=25534976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/011720 WO1994013304A2 (en) 1992-12-11 1993-12-03 Antacid composition and method of production

Country Status (10)

Country Link
EP (1) EP0673253A1 (en)
JP (1) JPH08504442A (en)
KR (1) KR950703982A (en)
AU (1) AU6390894A (en)
CA (1) CA2150383A1 (en)
CZ (1) CZ148695A3 (en)
FI (1) FI952859A (en)
NO (1) NO952261D0 (en)
SK (1) SK76595A3 (en)
WO (1) WO1994013304A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69413544T2 (en) * 1993-08-24 1999-05-27 Kappa Pharmaceuticals Ltd REDUCED ABSORPTION OF FATTY ACIDS
AU2585395A (en) 1994-05-09 1995-11-29 Chiron Corporation Retroviral vectors having a reduced recombination rate
US5874112A (en) * 1997-03-31 1999-02-23 Mcneil Ppc-Inc. Translucent antacid suspension
AU2002951438A0 (en) * 2002-09-17 2002-10-03 Nauveau Technology Investments Ltd Methods and compositions for treatment of excess stomach acid in mammals
RU2013148719A (en) * 2013-10-31 2015-05-10 Геннадий Гильфанович Галимов COMPOSITION BASED ON MAGNESIUM CHLORIDE HYDROXOALUMINATE, CONTAINING MAGNESIUM HYDROXIDE, AS A THERAPEUTIC DRUG
WO2016104367A1 (en) * 2014-12-22 2016-06-30 株式会社Ｌｔｔバイオファーマ Functional dyspepsia therapeutic drug

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843778A (en) * 1970-04-28 1974-10-22 Rorer Inc William H Antacids
US4271142A (en) * 1979-06-18 1981-06-02 Life Savers, Inc. Portable liquid antacids
FR2512344A1 (en) * 1981-09-08 1983-03-11 Af Aplicaciones Far Lab Stable antacid suspension of aluminium and/or magnesium hydroxide(s) - prepd. by mixing powdered prod. with water, fragmenting and dispersing to give particle size of 5-10 microns

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843778A (en) * 1970-04-28 1974-10-22 Rorer Inc William H Antacids
US4271142A (en) * 1979-06-18 1981-06-02 Life Savers, Inc. Portable liquid antacids
FR2512344A1 (en) * 1981-09-08 1983-03-11 Af Aplicaciones Far Lab Stable antacid suspension of aluminium and/or magnesium hydroxide(s) - prepd. by mixing powdered prod. with water, fragmenting and dispersing to give particle size of 5-10 microns

Also Published As

Publication number Publication date
NO952261L (en) 1995-06-08
KR950703982A (en) 1995-11-17
AU6390894A (en) 1994-07-04
FI952859A0 (en) 1995-06-09
NO952261D0 (en) 1995-06-08
SK76595A3 (en) 1997-01-08
JPH08504442A (en) 1996-05-14
WO1994013304A2 (en) 1994-06-23
CZ148695A3 (en) 1995-12-13
CA2150383A1 (en) 1994-06-23
FI952859A (en) 1995-06-09
EP0673253A1 (en) 1995-09-27

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