WO1994014453A1 - Hydroxy vitamin d3 compounds for treating skin atrophy - Google Patents
Hydroxy vitamin d3 compounds for treating skin atrophy Download PDFInfo
- Publication number
- WO1994014453A1 WO1994014453A1 PCT/DK1993/000426 DK9300426W WO9414453A1 WO 1994014453 A1 WO1994014453 A1 WO 1994014453A1 DK 9300426 W DK9300426 W DK 9300426W WO 9414453 A1 WO9414453 A1 WO 9414453A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hydroxy
- triene
- dihydroxy
- seco
- formula
- Prior art date
Links
- 0 C[C@](C*)[C@](CCCC1)CC[C@@](C)C1=CC=C(C[C@](C[C@@]1O)O)C1=C Chemical compound C[C@](C*)[C@](CCCC1)CC[C@@](C)C1=CC=C(C[C@](C[C@@]1O)O)C1=C 0.000 description 3
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94903742A EP0675722A1 (en) | 1992-12-23 | 1993-12-17 | Hydroxy vitamin d3 compounds for treating skin atrophy |
AU58088/94A AU678800B2 (en) | 1992-12-23 | 1993-12-17 | Hydroxy vitamin D3 compounds for treating skin atrophy |
JP6514698A JPH08504776A (en) | 1992-12-23 | 1993-12-17 | Hydroxyvitamin D3 compounds for treating skin atrophy |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9226860.6 | 1992-12-23 | ||
GB929226860A GB9226860D0 (en) | 1992-12-23 | 1992-12-23 | Novel treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1994014453A1 true WO1994014453A1 (en) | 1994-07-07 |
Family
ID=10727144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK1993/000426 WO1994014453A1 (en) | 1992-12-23 | 1993-12-17 | Hydroxy vitamin d3 compounds for treating skin atrophy |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0675722A1 (en) |
JP (1) | JPH08504776A (en) |
AU (1) | AU678800B2 (en) |
CA (1) | CA2150827A1 (en) |
GB (1) | GB9226860D0 (en) |
NZ (1) | NZ259318A (en) |
WO (1) | WO1994014453A1 (en) |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0667166A1 (en) * | 1993-09-01 | 1995-08-16 | Teijin Limited | Emulsion based on 1-alpha,24-dihydroxy-vitamine d3 |
EP0711558A1 (en) * | 1994-10-21 | 1996-05-15 | Unilever Plc | Compositions for topical application to skin, hair and nails |
DE19744127A1 (en) * | 1997-10-01 | 1999-04-15 | Schering Ag | New vitamin D derivatives with cyclopropyl rings in the side chains, processes and intermediates for their manufacture and their use in the manufacture of pharmaceuticals |
EP0979654A1 (en) * | 1998-03-04 | 2000-02-16 | Teijin Limited | Activated vitamin d 3? emulsion-type lotions |
WO2000064450A1 (en) * | 1999-04-23 | 2000-11-02 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Pharmaceutical composition |
WO2002017932A1 (en) * | 2000-08-30 | 2002-03-07 | Chugai Seiyaku Kabushiki Kaisha | Oct preparations |
WO2002034235A1 (en) * | 2000-10-27 | 2002-05-02 | Leo Pharma A/S | Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid |
WO2007036802A2 (en) * | 2005-07-07 | 2007-04-05 | Teva Pharmaceutical Industries Limited | Sublingual dosage form comrising vitamin d analogue, in particular calcitriol |
US7279477B2 (en) | 2001-01-26 | 2007-10-09 | Chugai Seiyaku Kabushiki Kaisha | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US7285562B2 (en) | 2003-08-01 | 2007-10-23 | Chugai Seiyaku Kabushiki Kaisha | Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors |
US7385063B2 (en) | 2001-01-26 | 2008-06-10 | Chugai Seiyaku Kabushiki Kaisha | Method for preparing imidazole derivatives |
US7449482B2 (en) | 2003-08-01 | 2008-11-11 | Chugai Seiyaku Kabushiki Kaisha | Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors |
US7524969B2 (en) | 2001-01-26 | 2009-04-28 | Chugai Seiyaku Kabushiki Kaisha | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
EP2056791A2 (en) * | 2006-08-29 | 2009-05-13 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical compositions including vitamin d and corticosteroid |
US7696365B2 (en) | 2003-08-01 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors |
US7709510B2 (en) | 2001-02-20 | 2010-05-04 | Chugai Seiyaku Kabushiki Kaisha | Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US7723366B2 (en) | 2001-02-20 | 2010-05-25 | Chugai Seiyaku Kabushiki Kaisha | Azole compounds as malonyl-CoA decarboxylase inhibitors for treating metabolic diseases |
US7786145B2 (en) | 2003-08-01 | 2010-08-31 | Chugai Seiyaku Kabushiki Kaisha | Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors |
EP2222635A2 (en) * | 2007-11-20 | 2010-09-01 | Abbott Laboratories | New vitamin d receptor activators and methods of making |
WO2016182258A3 (en) * | 2015-05-08 | 2017-01-12 | (주)동구바이오제약 | Pharmaceutical composition having improved stability and skin penetration |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4511639B2 (en) * | 1997-12-09 | 2010-07-28 | 中外製薬株式会社 | Cream containing vitamin D3 derivative |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001454A1 (en) * | 1990-07-18 | 1992-02-06 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Use of 20(r)-22-oxa-vitamin d analogues for the treatment of skin ageing |
WO1992003414A1 (en) * | 1990-08-15 | 1992-03-05 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Novel vitamin d analogues |
WO1994001398A1 (en) * | 1992-07-03 | 1994-01-20 | Bretting, Claus, Aage, Svensgaard | Vitamin d analogues |
-
1992
- 1992-12-23 GB GB929226860A patent/GB9226860D0/en active Pending
-
1993
- 1993-12-17 WO PCT/DK1993/000426 patent/WO1994014453A1/en not_active Application Discontinuation
- 1993-12-17 NZ NZ259318A patent/NZ259318A/en unknown
- 1993-12-17 EP EP94903742A patent/EP0675722A1/en not_active Withdrawn
- 1993-12-17 AU AU58088/94A patent/AU678800B2/en not_active Ceased
- 1993-12-17 JP JP6514698A patent/JPH08504776A/en active Pending
- 1993-12-17 CA CA002150827A patent/CA2150827A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001454A1 (en) * | 1990-07-18 | 1992-02-06 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Use of 20(r)-22-oxa-vitamin d analogues for the treatment of skin ageing |
WO1992003414A1 (en) * | 1990-08-15 | 1992-03-05 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Novel vitamin d analogues |
WO1994001398A1 (en) * | 1992-07-03 | 1994-01-20 | Bretting, Claus, Aage, Svensgaard | Vitamin d analogues |
Non-Patent Citations (1)
Title |
---|
SUGIMOTO T. ET AL.: "Combined effects of dexamethasone and 1,25-Dihydroxyvitamin D3 on parathyroid hormone secretion in cultured bovine parathyroid cells", ENDOCRINOLOGY, vol. 125, no. 2, 1989, pages 638 - 641 * |
Cited By (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0667166A4 (en) * | 1993-09-01 | 1995-11-02 | Teijin Ltd | 1-g(a),24-(OH) 2?-VITAMIN D 3? EMULSION COMPOSITION. |
US5612327A (en) * | 1993-09-01 | 1997-03-18 | Teijin Limited | 1α,24-(OH)2 -cholecalciferol emulsion composition and method for treating psoriasis |
EP0667166A1 (en) * | 1993-09-01 | 1995-08-16 | Teijin Limited | Emulsion based on 1-alpha,24-dihydroxy-vitamine d3 |
EP0711558A1 (en) * | 1994-10-21 | 1996-05-15 | Unilever Plc | Compositions for topical application to skin, hair and nails |
US7071344B1 (en) | 1997-10-01 | 2006-07-04 | Schering Ag | Vitamin D derivatives with cyclopropyl rings in the lateral chains, a method and intermediate products for the production thereof and the utilization thereof for producing medicaments |
DE19744127A1 (en) * | 1997-10-01 | 1999-04-15 | Schering Ag | New vitamin D derivatives with cyclopropyl rings in the side chains, processes and intermediates for their manufacture and their use in the manufacture of pharmaceuticals |
DE19744127B4 (en) * | 1997-10-01 | 2006-10-05 | Schering Ag | New vitamin D derivatives with side-chain cyclopropyl rings, processes and intermediates for their preparation and their use in the manufacture of medicaments |
EP0979654A1 (en) * | 1998-03-04 | 2000-02-16 | Teijin Limited | Activated vitamin d 3? emulsion-type lotions |
CZ298971B6 (en) * | 1998-03-04 | 2008-03-26 | Teijin Limited | Lotions based on Active vitamin D3 emulsions |
EP0979654A4 (en) * | 1998-03-04 | 2002-05-08 | Teijin Ltd | Activated vitamin d 3 emulsion-type lotions |
US6753013B1 (en) | 1999-04-23 | 2004-06-22 | Leo Pharmaceutical Products, Ltd. A/S | Pharmaceutical composition |
CZ303142B6 (en) * | 1999-04-23 | 2012-05-02 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) | Pharmaceutical composition for dermal use |
EP2450043A1 (en) * | 1999-04-23 | 2012-05-09 | Leo Pharma A/S | Pharmaceutical composition for dermal use to treat psoriasis, sebopsoriasis or seborrhoic dermatitis comprising a vitamin D and a corticosteroid |
EP2450043B1 (en) | 1999-04-23 | 2016-08-17 | Leo Pharma A/S | Pharmaceutical composition for dermal use to treat psoriasis comprising calcipotriol and betamethasone |
HRP20010779B1 (en) * | 1999-04-23 | 2011-02-28 | Leo Pharmaceutical Products Ltd. A/S (Loevens Kemiske Fabrik Produktionsaktieselskab) | Pharmaceutical composition |
KR100694526B1 (en) * | 1999-04-23 | 2007-03-13 | 레오 파마 에이/에스 | Pharmaceutical composition |
EP1178808B2 (en) † | 1999-04-23 | 2019-06-12 | Leo Pharma A/S | Non-aqueous pharmaceutical composition for dermal use to treat psoriasis comprising a vitamin d, a corticosteroid and a solvent component |
EP3146969B1 (en) | 1999-04-23 | 2018-06-20 | Leo Pharma A/S | Ointment for the topical treatment of psoriasis |
EP2455083A1 (en) * | 1999-04-23 | 2012-05-23 | Leo Pharma A/S | Pharmaceutical composition for dermal use comprising calcipotriol and a corticosteroid |
EP3146969A1 (en) * | 1999-04-23 | 2017-03-29 | Leo Pharma A/S | Ointments for the topical treatment of psoriasis |
WO2000064450A1 (en) * | 1999-04-23 | 2000-11-02 | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) | Pharmaceutical composition |
EP2915534A1 (en) * | 1999-04-23 | 2015-09-09 | Leo Pharma A/S | Pharmaceutical composition for dermal use to treat psoriasis comprising a vitamin D and a corticosteroid |
WO2002017932A1 (en) * | 2000-08-30 | 2002-03-07 | Chugai Seiyaku Kabushiki Kaisha | Oct preparations |
AU2001282521B2 (en) * | 2000-08-30 | 2005-12-15 | Chugai Seiyaku Kabushiki Kaisha | OCT preparations |
CZ305984B6 (en) * | 2000-10-27 | 2016-06-08 | Leo Pharma A/S | Substantially anhydrous pharmaceutical gel composition for application to skin containing vitamin D or one analog thereof and corticosteroid |
US6787529B2 (en) | 2000-10-27 | 2004-09-07 | Leo Pharmaceutical Products Ltd. A/S | Topical composition |
WO2002034235A1 (en) * | 2000-10-27 | 2002-05-02 | Leo Pharma A/S | Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid |
US7524969B2 (en) | 2001-01-26 | 2009-04-28 | Chugai Seiyaku Kabushiki Kaisha | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US7385063B2 (en) | 2001-01-26 | 2008-06-10 | Chugai Seiyaku Kabushiki Kaisha | Method for preparing imidazole derivatives |
US7279477B2 (en) | 2001-01-26 | 2007-10-09 | Chugai Seiyaku Kabushiki Kaisha | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US8119819B2 (en) | 2001-01-26 | 2012-02-21 | Chugai Seiyaku Kabushiki Kaisha | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US8110686B2 (en) | 2001-02-20 | 2012-02-07 | Chugai Seiyaki Kabushiki Kaisha | Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US7723366B2 (en) | 2001-02-20 | 2010-05-25 | Chugai Seiyaku Kabushiki Kaisha | Azole compounds as malonyl-CoA decarboxylase inhibitors for treating metabolic diseases |
US7709510B2 (en) | 2001-02-20 | 2010-05-04 | Chugai Seiyaku Kabushiki Kaisha | Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators |
US7696365B2 (en) | 2003-08-01 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors |
US7786145B2 (en) | 2003-08-01 | 2010-08-31 | Chugai Seiyaku Kabushiki Kaisha | Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors |
US7897615B2 (en) | 2003-08-01 | 2011-03-01 | Chugai Sciyaku Kabushiki Kaisha | Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors |
US8080665B2 (en) | 2003-08-01 | 2011-12-20 | Chugai Seiyaku Kabushiki Kaisha | Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors |
US7449482B2 (en) | 2003-08-01 | 2008-11-11 | Chugai Seiyaku Kabushiki Kaisha | Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors |
US7285562B2 (en) | 2003-08-01 | 2007-10-23 | Chugai Seiyaku Kabushiki Kaisha | Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors |
WO2007036802A3 (en) * | 2005-07-07 | 2007-08-30 | Teva Pharma | Sublingual dosage form comrising vitamin d analogue, in particular calcitriol |
WO2007036802A2 (en) * | 2005-07-07 | 2007-04-05 | Teva Pharmaceutical Industries Limited | Sublingual dosage form comrising vitamin d analogue, in particular calcitriol |
EP2056791A2 (en) * | 2006-08-29 | 2009-05-13 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical compositions including vitamin d and corticosteroid |
EP2222635A2 (en) * | 2007-11-20 | 2010-09-01 | Abbott Laboratories | New vitamin d receptor activators and methods of making |
WO2016182258A3 (en) * | 2015-05-08 | 2017-01-12 | (주)동구바이오제약 | Pharmaceutical composition having improved stability and skin penetration |
Also Published As
Publication number | Publication date |
---|---|
EP0675722A1 (en) | 1995-10-11 |
AU678800B2 (en) | 1997-06-12 |
AU5808894A (en) | 1994-07-19 |
GB9226860D0 (en) | 1993-02-17 |
CA2150827A1 (en) | 1994-07-07 |
JPH08504776A (en) | 1996-05-21 |
NZ259318A (en) | 1997-08-22 |
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