WO1995014704A1 - Bis(pentaerythritol phosphate alcohol) alkylphosphonate - Google Patents
Bis(pentaerythritol phosphate alcohol) alkylphosphonate Download PDFInfo
- Publication number
- WO1995014704A1 WO1995014704A1 PCT/US1994/013174 US9413174W WO9514704A1 WO 1995014704 A1 WO1995014704 A1 WO 1995014704A1 US 9413174 W US9413174 W US 9413174W WO 9514704 A1 WO9514704 A1 WO 9514704A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pentaerythritol phosphate
- phosphate alcohol
- bis
- compound
- alcohol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65748—Esters of oxyacids of phosphorus the cyclic phosphorus atom belonging to more than one ring system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/49—Phosphorus-containing compounds
- C08K5/51—Phosphorus bound to oxygen
- C08K5/52—Phosphorus bound to oxygen only
- C08K5/527—Cyclic esters
Definitions
- the present invention relates to novel flame retardant compounds which are bis(pentaerythritol phosphate alcohol) alkylphosphonate compounds.
- the present novel bis(pentaerythritol phosphate alcohol) alkylphosphonate compounds are of the formula:
- R is alkyl, for example alkyl of from one to four carbon atoms, preferably methyl.
- One process for forming the above-described novel compounds is by the transesterification of a diphenyl alkyl phosphonate carrying the desired alkyl group with pentaerythritol phosphate alcohol which has the formula O - CH 2
- the phosphonate reagent is of the formula (ArO) 2 P(0)R, where Ar is substituted or unsubstituted phenyl and R is alkyl as previously described.
- the transesterification reaction is advantageously conducted at elevated temperature (e.g., a temperature of from about 170°C to about 200°C) in a high boiling organic solvent, such as an aryl phosphate solvent (as described in U.S. Patent No. 5,237,085), using an appropriate transesterification catalyst (e.g., magnesium dichloride, sodium phenoxide, or the like) .
- the reaction mixture will contain the desired crude product with a phenolic by-product.
- the crude product can be triturated with a solvent such as acetonitrile or methanol to give the desired, purified product.
- a solvent such as acetonitrile or methanol
- An alternative way of preparing the novel compounds is by the reaction of pentaerythritol phosphate alcohol, a trialkylamine, such as triethylamine, and an alkylphosphonic dihalide, such as methylphosphonic dichloride, in an appropriate solvent, such as acetonitrile, under cooling at essentially ambient temperature (e.g., 20°C to about 30°C) .
- Pentaerythritol phosphate alcohol (90.1 gm, 0.5 mole), diphenyl methylphosphonate (62.0 gm, 0.25 mole), magnesium chloride (238 mg, 2.5 mmole, 1.0 mole % on diphenyl methylphosphonate) , and 85 mL of isopropyl triarylphosphate (PHOSFLEX 4IP brand from Akzo Chemicals Inc.) were charged to a 250 mL, four neck, round bottom flask with mechanical stirrer, thermometer, 3.5 inch
- Vigreux column distillation head and receiver with vacuum connection. A vacuum of 60 mm Hg was applied, and the reaction mixture was heated.
- the flask temperature was raised from room temperature to 193°C. About thirty-five minutes thereafter, slow distillation of phenol began at a flask temperature of 185°C, distillation head temperature of 97°C, and 35 mm Hg pressure. One hour later, with the flask at 200°C, the distillation head at 90°C, and 10 mm Hg pressure, the reaction was cooled and 1000 mg of magnesium chloride was added. Then, the reactor was heated for two hours at 195°C (down to 5.5 mm Hg pressure) before cooling after no further distillation occurred.
- the system was cooled to 100°C at which time two phases were observed, one liquid and the other a gummy mass. After further cooling to 80°C, 100 ml of methanol was added which dissolved the liquid phase and part of the gummy mass leaving behind a white solid. The solid was removed by filtration and washed three times with 20 ml of methanol. The washed product was dried in an oven overnight at room temperature and 1 mm Hg pressure yielding 12.0 gm of a white powder having a decomposition about 325°C.
- Pentaerythritol phosphate alcohol (63.4 g, 0.36 mole), triethylamine (49.1 mL, 35.6 g, 0.36 mole), and 150 L of acetonitrile were charged to a 250 mL 4-necked round-bottomed flask with mechanical stirrer, thermometer, nitrogen inlet, and dropping funnel containing methylphosphonic dichloride (23.4 g, 0.18 mole) and 5 L acetonitrile.
- the reactor was stirred and cooled with an ice bath as the methylphosphonic dichloride was added dropwise over fifteen minutes while maintaining a pot temperature of 20°C-30°C.
- the resulting thick slurry was heated to reflux for twelve hours, cooled to 25°C, and filtered.
- the white solid was washed four times with 50 mL of methanol and then dried overnight at 100°C/ 2 mm Hg.
- the white product weighed 61.4 g (81.2 % yield) and had properties substantially identical to the product from Example 1.
- Example 2 The compound of Example 2, hereinafter abbreviated as "Bis(PEPA)MP", was evaluated as a flame retardant in polypropylene in the three formulations listed below from the following ingredients.
- the flame retardancy data was as follows:
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002177059A CA2177059A1 (en) | 1993-11-22 | 1994-11-15 | Bis(pentaerythritol phosphate alcohol) alkylphosphonate |
JP7515124A JPH10500656A (en) | 1993-11-22 | 1994-11-15 | Bis (pentaerythritol phosphate alcohol) alkyl phosphonate |
EP95902564A EP0730600A4 (en) | 1993-11-22 | 1994-11-15 | Bis(pentaerythritol phosphate alcohol) alkylphosphonate |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/155,666 US5362898A (en) | 1993-11-22 | 1993-11-22 | Bis(pentaerythritol phosphate alcohol) alkylphosphonate |
US08/155,666 | 1993-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995014704A1 true WO1995014704A1 (en) | 1995-06-01 |
Family
ID=22556302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1994/013174 WO1995014704A1 (en) | 1993-11-22 | 1994-11-15 | Bis(pentaerythritol phosphate alcohol) alkylphosphonate |
Country Status (6)
Country | Link |
---|---|
US (3) | US5362898A (en) |
EP (1) | EP0730600A4 (en) |
JP (1) | JPH10500656A (en) |
CN (1) | CN1135755A (en) |
CA (1) | CA2177059A1 (en) |
WO (1) | WO1995014704A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5536863A (en) * | 1995-05-09 | 1996-07-16 | Akzo Nobel N.V. | (Pentaerythritol phosphate alcohol) (cyclic neopentylene glycol) phosphite and phosphonate |
US5536862A (en) * | 1995-05-09 | 1996-07-16 | Akzo Nobel N.V. | Pentaerythritol phosphate alcohol-containing phosphonate and phosphite compounds |
US5614081A (en) * | 1995-06-12 | 1997-03-25 | Betzdearborn Inc. | Methods for inhibiting fouling in hydrocarbons |
US5633301A (en) * | 1996-05-23 | 1997-05-27 | Akzo Nobel Nv | Flame retardant polyketone composition |
US5858176A (en) * | 1997-04-22 | 1999-01-12 | Betzdearborn Inc. | Compositions and methods for inhibiting fouling of vinyl monomers |
US6455722B1 (en) * | 2001-06-29 | 2002-09-24 | Pabu Services, Inc. | Process for the production of pentaerythritol phosphate alcohol |
DE102011002639A1 (en) * | 2011-01-13 | 2012-07-19 | Evonik Oxeno Gmbh | Process for the preparation of biphephos |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3883478A (en) * | 1973-12-07 | 1975-05-13 | Fmc Corp | Flame-Retardant Polyester Fiber Compositions |
US4152373A (en) * | 1975-09-22 | 1979-05-01 | Stauffer Chemical Company | Process for preparing diaryl methylphosphonate and derivatives thereof |
US4801625A (en) * | 1987-08-27 | 1989-01-31 | Akzo America Inc. | Bicyclic phosphate ether, ester, and carbonate intumescent flame retardant compositions |
US5235085A (en) * | 1992-07-10 | 1993-08-10 | Akzo N.V. | Process for forming bis(pentaerythritol phosphate) carbonate |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA866204A (en) * | 1971-03-16 | Gordon Irving | Ester of phosphorus and method of preparation thereof | |
US3494986A (en) * | 1963-07-01 | 1970-02-10 | Hooker Chemical Corp | Process for the preparation of triesters of phosphorus |
US3772414A (en) * | 1971-01-05 | 1973-11-13 | Monsanto Co | Preparation of esters of phosphorus acids |
US3965220A (en) * | 1971-06-24 | 1976-06-22 | Monsanto Company | Preparation of esters of phosphorus acids |
US3789091A (en) * | 1971-11-15 | 1974-01-29 | Mobil Oil Corp | Cyclic phosphonate esters and their preparation |
US5237085A (en) * | 1992-07-10 | 1993-08-17 | Akzo N V | Process for the formation of pentaerythritol-based phosphorous heterocycles |
-
1993
- 1993-11-22 US US08/155,666 patent/US5362898A/en not_active Expired - Fee Related
-
1994
- 1994-08-30 US US08/298,249 patent/US5486640A/en not_active Expired - Fee Related
- 1994-08-30 US US08/298,250 patent/US5486639A/en not_active Expired - Fee Related
- 1994-11-15 WO PCT/US1994/013174 patent/WO1995014704A1/en not_active Application Discontinuation
- 1994-11-15 EP EP95902564A patent/EP0730600A4/en not_active Withdrawn
- 1994-11-15 CN CN94194249.XA patent/CN1135755A/en active Pending
- 1994-11-15 JP JP7515124A patent/JPH10500656A/en active Pending
- 1994-11-15 CA CA002177059A patent/CA2177059A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3883478A (en) * | 1973-12-07 | 1975-05-13 | Fmc Corp | Flame-Retardant Polyester Fiber Compositions |
US4152373A (en) * | 1975-09-22 | 1979-05-01 | Stauffer Chemical Company | Process for preparing diaryl methylphosphonate and derivatives thereof |
US4801625A (en) * | 1987-08-27 | 1989-01-31 | Akzo America Inc. | Bicyclic phosphate ether, ester, and carbonate intumescent flame retardant compositions |
US5235085A (en) * | 1992-07-10 | 1993-08-10 | Akzo N.V. | Process for forming bis(pentaerythritol phosphate) carbonate |
Non-Patent Citations (1)
Title |
---|
See also references of EP0730600A4 * |
Also Published As
Publication number | Publication date |
---|---|
CA2177059A1 (en) | 1995-06-01 |
US5486639A (en) | 1996-01-23 |
US5486640A (en) | 1996-01-23 |
JPH10500656A (en) | 1998-01-20 |
CN1135755A (en) | 1996-11-13 |
US5362898A (en) | 1994-11-08 |
EP0730600A4 (en) | 1997-03-19 |
EP0730600A1 (en) | 1996-09-11 |
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