WO1995029635A1 - System for closing a percutaneous trocar puncture - Google Patents
System for closing a percutaneous trocar puncture Download PDFInfo
- Publication number
- WO1995029635A1 WO1995029635A1 PCT/US1995/005187 US9505187W WO9529635A1 WO 1995029635 A1 WO1995029635 A1 WO 1995029635A1 US 9505187 W US9505187 W US 9505187W WO 9529635 A1 WO9529635 A1 WO 9529635A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- puncture
- filament
- opening
- tissue
- tract
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00637—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00654—Type of implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00659—Type of implements located only on one side of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00663—Type of implements the implement being a suture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00898—Material properties expandable upon contact with fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0406—Pledgets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0409—Instruments for applying suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0458—Longitudinal through hole, e.g. suture blocked by a distal suture knot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0464—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors for soft tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
Definitions
- This application relates generally to laparoscopic surgical procedures, and more particularly to a system and method for sealing the percutaneous puncture formed by a trocar during such procedures in order to prevent tissue contiguous with the puncture from herniating thereafter.
- hernia is one of the most common ailments of mankind. Basically, a hernia is a weakness or hole in the abdominal wall through which abdominal contents such as bowels may protrude. In general, it relates to the abnormal protrusion of an organ or part of an organ or a portion of tissue through an aperture in its containing cavity.
- the usual, but not the only, hernia that is typically treated is congenital in origin, called an indirect inguinal hernia, and is due to the failure of the inner lining of the abdomen, called the peritoneum, to seal itself at the opening of the inguinal canal. Inguinal or groin hernias normally occur at one or more of three locations.
- the first location is in the weakened wall of the inguinal floor of the abdomen in Hesselback's triangle.
- This type of hernia is called a direct hernia.
- the second type of hernia is an indirect hernia that occurs at the internal ring adjacent to the vas deferens as it exits the abdomen to become part of the spermatic cord.
- the third type is a femoral hernia that occurs adjacent and medial to the femoral blood vessels. All hernias represent a potentially life threatening condition and once diagnosed they should be repaired unless there is some contraindication.
- a less invasive surgical procedure to repair hernias has been used in conjunction with a laparoscope.
- a prosthetic patch is inserted down the length of a trocar and forced out of the tube and moved into a desired position.
- Post ⁇ operative problems are decreased by this procedure because of the smaller external wound left by the surgical tube.
- the patch still can shift before tissue has grown onto it.
- the patch also can be sutured to the transversalis fiasco or peritoneum to minimize movement. It has typically been difficult to attach patches with sutures using the laparoscope because of difficulties in viewing and in maneuvering through the laparoscope.
- the laparoscopic techniques for hernia repair have generally proven to be less invasive, they still leave something to be desired from the standpoint of effectiveness.
- hernias that are congenital in origin such as an indirect inguinal hernia
- external trauma such as an indirect inguinal hernia
- laparoscopic surgery itself, can lead to a number of both local and general complications, such as herniation at the site of the percutaneous laparoscopic puncture with or without the formation adhesions thereat.
- herniation occurs in an appreciable percentage of these procedures within several months of the procedure. The herniation occurs because the muscle tissue at the location of the puncture is damaged during the procedure.
- This muscle tissue then weakens and due to internal pressure the intestines or other organs of the abdominal cavity are pushed through this weakened area.
- Such muscle failure results in a direct hernia, the repair of which typically requires a synthetic mesh to reinforce the damaged muscle tissue.
- a surgical implantation device arranged to be placed within a patient's body to seal an existing hernial rupture.
- the device is arranged to be used with a laparoscope to minimize the external wound necessary.
- the implantation device is arranged to be compressed into an implanting condition for placement at the opening in the transversalis fascia from the interior of the peritoneum using a laparoscope and then to be expanded into a deployed condition to securely seal the opening.
- the peritoneum can either be left intact and pushed through the fascia opening by the surgical tube and held in place by the surgical implant device at the peritoneum, or can be pierced and the surgical tube and device can be positioned directly in the fascia opening.
- the device of the Seid patent appears to overcome some of the short fallings of traditional surgical hernia repair by introducing the device into the abdominal cavity through a laparoscopic port and then positioned from the inside of the peritoneum outward to treat an existing inguinal hernia, it never the less has its own shortcomings.
- one shortcoming of the Seid device is that the laparoscopic procedure utilized to introduce the device for the repair of another hernia, is likely to become a site of a future herniation.
- the closure device is arranged to be used with (deployed by) an instrument which comprises a carrier in the form of a tubular member.
- the tubular member has a proximally located portion and a distally located portion.
- the latter includes an open free end arranged to be introduced through the incision or puncture.
- the proximately located portion of the tubular member is arranged to be located out of the body of the being when the distally located portion is extended through the incision or puncture.
- the closure device comprises three components, namely, an anchor member, a sealing member, and a filament, e.g., suture.
- the anchor member includes a tissue engaging portion configured to pass through the puncture in one direction but resistant to passage therethrough in the opposite direction.
- the sealing member is formed of a hemostatic material, such as compressed collagen foam, and has a tissue engaging portion.
- the filament is connected between the anchor member and the sealing member in a pulley-like arrangement so that they may be moved relative to each other by the application of a pulling force on the filament.
- the instrument is arranged to expel the anchor member through the puncture, e.g., into the artery, and to draw its tissue engaging portion into engagement with the tissue contiguous with the puncture.
- the filament extends through the instrument to a point outside the body of the being and is arranged to be drawn in the proximal direction, whereupon the portion of the filament connecting the anchor member causes the tissue engaging portion of the sealing member to move with respect to the anchor member, thereby drawing the anchor member and sealing member together.
- the closure means comprises anchoring means, sealing means, and filament means, with the filament means coupling the anchoring means and the sealing means.
- the introducer means comprises a tubular member having a distal free end insertable into the puncture tract and through the opening in the blood vessel wall.
- the carrier means is insertable through the introducer means and includes means to expel the anchoring means therefrom. Moreover, the carrier means is retractable with respect to the introducer means after the anchoring means has been expelled from the carrier means, so that when it is retracted it draws the anchoring means into engagement with the distal free end of the introducer means.
- the introducer means and the carrier means are coupled for movement together to draw the anchoring means which is now in engagement with the distal end of the introducer means into engagement with the interior tissue of the vessel generally adjacent the opening in the wall there f.
- the filament means is operative to move the anchoring means and the sealing means relative to each other to cause the sealing means to engage tissue generally adjacent the puncture outside of the vessel.
- the anchor member includes a tissue engaging portion configured to pass through the puncture in one direction but resistant to passage therethrough in the opposite direction.
- the sealing member is formed of a hemostatic material, such as compressed collagen foam.
- the spacer member is mounted upon the suture, and is slidable thereon, and is positioned between the anchor member and the sealing member.
- the filament member is connected between the anchor member and the sealing member in a pulley-like arrangement so that the members may be moved relative to each other by the application of a pulling force on the filament.
- the instrument is arranged to expel the anchor member through the puncture, e.g. , into the artery, and to draw its tissue engaging portion into engagement with the tissue contiguous with the puncture.
- the filament extends through the instrument to a point outside the body of the being and is arranged to be drawn in the proximal direction, whereupon the portion of the filament connecting the anchor member and the sealing member causes the sealing member to move with respect to said anchor member and into engagement with the spacer member thereby drawing the anchor member, spacer member and sealing member together.
- This action causes the sealing member to seal the puncture from the flow of fluid therethrough.
- the presence of the spacer member prohibits the sealing member from contacting the arterial wall and thereby possibly entering into the artery where a portion could conceivably break off and flow distally or cause the creation of an embolism.
- the closure comprises an elongated rigid anchor member formed of a resorbable material, a sealing member formed of a resorbable material, e.g., compressed collagen plug, and a thin resorbable material filament, e.g. , a suture, connecting the anchor member and the sealing member.
- the anchor member is located in the interior of the vessel, with the sealing member being located in the puncture tract.
- An elongated reinforcing filament or ribbon (either apertured or unapertured) , formed of a resorbable material, is incorporated in the elongated anchor member to prevent any portion of it from breaking away in the event that the anchor is loaded beyond its breaking point.
- the devices disclosed in the aforementioned applications can be used to effect the sealing of a percutaneous puncture formed during a laparoscopic procedure of the abdomen or an endoscopic procedure of the thoracic cavity, or some other minimally invasive procedure performed percutaneously.
- the devices of this invention not only seal the puncture, but also block the egress of tissue therethrough.
- the devices may include means to reinforce the tissue at the tissue opening so that the long-term strength of the scar tissue forming thereat is enhanced. This action may render the puncture site resistant to herniation in the long term.
- internal tissue e.g., the peritoneum, the thoracic cavity wall, or some other internal tissue
- a system and method of use for introducing a device through a percutaneous puncture into some internal tissue of a living being, e.g., the peritoneum, formed during a minimally invasive surgical procedure, e.g., a laparoscopic, endoscopic, or arthroscopic procedure, to seal the opening and/or prevent the egress of tissue into the puncture.
- the percutaneous puncture includes a puncture tract extending from the skin to the opening in the internally located tissue.
- the system includes a deployment instrument and a sealing device.
- the sealing device basically comprises anchoring means and filament means.
- the anchoring means is arranged to be extended through the tract and the opening and is orientable for engaging the interior of the internal tissue adjacent the opening to render the anchoring means resistant to passage back through the opening.
- the filament means is coupled to said anchoring means and includes at least a first portion located outside the internal tissue extending through the tract and coupled to the anchoring means and cooperating with the anchoring means for holding the anchoring means in place within the puncture. By so doing the anchoring means serves to block at least a portion of the opening.
- the device is introduced into the puncture by the deployment instrument forming a portion of the system.
- Fig. 1 is a side elevation view, partially in section, showing a trocar extending percutaneously into the abdomen of a living being, with a deployment instrument and one embodiment of a sealing device of the system of the subject invention located therein for placement of the device into the percutaneous puncture;
- Fig. 2 is a side elevational view like Fig. 1 but showing the subject invention at an initial step in the ejection of a portion of the device of Fig. 1 from the deployment instrument;
- Fig. 3 is a side elevational view like Fig. 2 but showing the subject invention at subsequent time, i.e., immediately after the removal of the deployment instrument and trocar from the percutaneous puncture leaving the device of Fig. 1 in place;
- Fig. 4 is a side elevational view like Fig. 3 but showing the subject invention at yet a further time, i.e., when a tamping component of the deployment instrument is used to deform a portion of the device of Fig. 1 in the percutaneous puncture;
- Fig. 5 is a side elevational view like Fig. 4 but showing the device of Fig. 1 of the subject invention after it is fully installed within the percutaneous puncture;
- Fig. 6 is an isometric view of the embodiment of the device of Fig. 1 of the subject invention during its fabrication;
- Fig. 7 is an isometric view like that of Fig. 6 but showing the device of Fig. 1 in its completed state ready for disposition within the deployment instrument shown in Fig. 1;
- Fig. 8 is an enlarged isometric view, partially broken away, of the anchor component of the device of Fig. 1;
- Fig. 9 is an enlarged isometric view of the plug component of the device of Fig. 1;
- Fig. 10 is an enlarged sectional view taken along line 10 - 10 of Fig. 1;
- Fig. 11 is an enlarged sectional view taken along line
- Fig. 12 is an enlarged sectional view taken along line
- Fig. 13 is an enlarged sectional view taken along line
- Fig. 14 is an enlarged isometric view of an alternative embodiment of a sealing device constructed in accordance with the subject invention.
- Fig. 15 is a side elevation view, partially in section, showing a trocar extending percutaneously into the abdomen of a living being, with a conventional grasper used as a deployment instrument extending through the trocar deploying the embodiment of the device of Fig. 14 into a percutaneous puncture;
- Fig. 16 is a side elevational view, like Fig. 15, but showing the device of Fig. 14 being released from the deployment instrument;
- Fig. 17 is a side elevational, view like Fig. 16, but showing the device of Fig. 14 at subsequent time, i.e., immediately after the removal of the deployment instrument from the percutaneous puncture leaving the device in within the abdomen;
- Fig. 18 is a side elevational view, like Fig. 17, but showing the device of Fig. 14 at yet a further time when a portion of the device is retracted against the distal end of the trocar;
- Fig. 19 is a side elevational view, like Fig. 18, but showing the device of Fig. 14 brought up against the inner surface of the peritoneum over the opening in the percutaneous puncture;
- Fig. 20 is a side elevational view, like Fig. 19, but showing the device of Fig. 14 being sutured in place to fully install it within the percutaneous puncture;
- Fig. 21 is a sectional view taken along line 21 - 21 of Fig. 20;
- Fig. 22 is a plan view of the sealing device of Fig.
- Fig. 23 is a side elevational view, like Fig. 15, but showing another alternative embodiment of a sealing device of this invention during the comparable step in the placement thereof as the device shown in Fig. 14;
- Fig. 24 is a side elevational view, like Fig. 20, but showing the location of a portion of the sealing device of Fig. 23 in place in the puncture tract to secure the device in place;
- Fig. 25 is a side elevational, like that of Fig. 24, showing the sealing device of Fig. 23 being locked in place to fully install it within the percutaneous puncture;
- Fig. 26 is an elevational view of an alternative embodiment of an anchoring member which can be used in any of the sealing devices of this invention.
- Fig. 27 is an elevational view, like that of Fig. 26, showing yet another alternative embodiment of an anchoring member which can be used in any of the sealing devices of this invention.
- Fig. 28 is an elevational view, like that of Figs. 26 and 27, showing still another alternative embodiment of an anchoring member which can be used in any of the sealing devices of this invention.
- the penetratable tissue comprises the peritoneum or the lining of the thoracic cavity, and that tissue is designated by the reference number 24.
- the percutaneous puncture includes an opening 26 in the tissue and a tract 28 extending from the surface of the skin 30 to the opening through the underlying tissue, e.g., the fat/fascia and muscle.
- the subject invention can be used to reinforce or otherwise enhance the long-term strength of scar tissue which may form at any internal puncture site and to prevent the passage of fluid or tissue through the puncture.
- the description of the preferred embodiment instrument and device to follow is directed to the closing off of percutaneous incisions or punctures in the abdominal cavity or in the thoracic cavity, the subject invention has much more wide-spread applications.
- the device 20 is arranged to be extended into the puncture by means of a deployment instrument 32.
- the deployment instrument is arranged to be extended through a conventional or non-conventional trocar, in order to place the device 20 in position.
- the trocar is shown schematically in Fig. 1 and designated by the reference number 34. It should be noted at this point that in some applications the use of a trocar may be obviated so that the deployment instrument 32, per se, can be inserted through the puncture to place the device 20 in the desired position within the puncture.
- the device 20 is arranged to be deployed into the puncture by the deployment instrument 32 so that a first portion of it (to be described later) is extended through the opening 26 and makes contact with the adjacent, e.g., contiguous, tissue, while a second portion of it (also to be described later) is within the puncture tract 28 to seal the puncture tract from the flow of fluid therethrough.
- a first portion of it to be described later
- a second portion of it also to be described later
- one or both of those portions of the device include means, e.g., reinforcing means, so that the long-term strength of scar tissue which will form at the opening 26 is improved, thereby making that scar tissue resistant to subsequent herniation.
- the device 20 basically comprises four components, namely, a sealing member 36, an anchoring member 38, a holding member 40, and a positioning filament 42.
- a standard, conventional, e.g., curved stainless steel, needle 44 is secured to one end of the filament, and thus, may be considered as a fifth component of the device 20.
- the function of the needle 44 will be described later.
- the sealing member 36 is deformable and is arranged to be located within the puncture tract and deformed therein to seal the tract from the flow of fluid therethrough. As best seen in Figs.
- the sealing member 36 basically comprises a strip of a compressible, resorbable, collagen foam, such as that sold by Colla-Tec, Inc. of Plainsboro, NJ 08536.
- the strip of collagen foam includes a thin web or strip of a non- resorbable, e.g., dacron, reinforcing mesh 46 embedded within it.
- the mesh 46 serves to aid in reinforcing the scar tissue which forms adjacent the opening 26 in the tissue wall 24 when the plug member is in place. It should be pointed out at this juncture that other reinforcing materials, e.g., resorbable suture materials such as that sold under the trademark DEXON by Davis + Geek of Wayne, NJ 07470, can be used in the sealing member, if desired.
- the reinforcing materials can take various configurations, e.g., filaments, meshes, strips, bands, etc. In fact, if desired, it is contemplated that no reinforcing means be used in the sealing member 36, particularly if the anchoring member includes reinforcing means (to be described later) .
- the strip 36 is folded in two as shown in Fig. 9 and includes a pair of apertures 48 and 50 extending through the folded over strip.
- the apertures 48 and 50 are arranged to have portions of the filament 42 extended therethrough, as will be described later, to couple the various components of the device 20 to one another.
- the folded over strip is arranged to be compressed from the state shown in Fig. 6 to that as shown in Fig. 7 so that the resultant plug member 36 is of reduced diameter, e.g., 8 mm, or width to fit within the deployment instrument as shown in Fig. 1.
- the anchoring member 38 is arranged to be seated inside the penetrated internal structure, e.g., the peritoneum, against the tissue thereof adjacent, e.g., contiguous, with the opening 26 through which it had been introduced.
- the anchoring member 38 is an elongated, low-profile component, similar to the anchor of the closure disclosed in the aforementioned copending patent applications, e.g., it may be formed of any resorbable material, such as a resorbable lactide/glycolide polymer sold by Medisorb Technologies International L.P. under the trade designation MEDISORB.
- the anchoring member is sufficiently rigid such that once it is in position within the abdominal cavity (as will be described later) it is resistant to deformation to preclude it from bending to pass back through the puncture through which it was first introduced.
- the anchoring member also includes reinforcing means, e.g., a strip or web 52 (Fig. 8) of a woven, non-resorbable mesh, such as dacron, embedded therein.
- the mesh serves to aid in reinforcing the scar tissue which forms adjacent the opening 26 in the tissue wall 24 when the anchoring member 38 is in place.
- other reinforcing materials e.g., resorbable suture materials such as that sold under the trademark DEXON by Davis + Geek of Wayne, NJ 07470, can be used in the anchoring member, if desired.
- the reinforcing materials can take various configurations, e.g., filaments, meshes, strips, bands, etc. In fact, if desired, it is contemplated that no reinforcing means be used in the anchoring member, particularly if the sealing member includes reinforcing means (described earlier) . In the embodiment of the invention wherein the anchoring member is reinforced it serves to reinforce any scar tissue which will form in the immediately adjacent tissue.
- the anchoring member 38 includes a pair of apertures 54 and 56 extending through it. These apertures are arranged to have portions of the filament 42 extended therethrough, as will be described later, to couple the various components of the device 20 to one another.
- the holding member 40 is a disk-like member having a pair of apertures 58 and 60 extending therethrough.
- the member 40 is rigid or stiff and is resorbable, e.g., is formed of the same material as that of the anchoring member.
- the apertures 58 and 60 are arranged to have portions of the filament 42 extended therethrough, as will be described later, to couple the various components of the device 20 to one another.
- the filament 42 preferably comprises a very thin flexible member, e.g., a resorbable suture, which connects the anchoring member 38, the sealing member 36, and the holding member 40 in a pulley-like arrangement.
- the filament is threaded through the aperture 58 in the holding member 40, from there through the aperture 48 in the plug member from one side to the opposite side thereof and out the aperture 50, from there into the aperture 56 in the anchoring member, from there out of aperture 54 in the anchoring member, from there in through the aperture 50 in the plug member from one side to the opposite side thereof and out the aperture 48, from there through the aperture 60 in the holding member 40.
- This arrangement produces a pair of proximal end portions 42A and 42B.
- a knot 62 is provided in the end portion 42A of the filament immediately proximally of the aperture 60 in the holding member 40.
- the needle 44 is connected to the free end of end portion 42B.
- the end portions 42A and 42B of the filament 42 are arranged to extend out of the deployment instrument 32 when the device 20 is disposed therein. Accordingly, as will be described later when the device 20 is deposited in the puncture 22 by the deployment instrument the end portions 42A and 42B of the filament 42 extend out of the puncture tract 28. This arrangement enables the filament 42 to be manipulated to effect the proper seating of the device in place. Moreover, the ends 42A and 42B are arranged to be secured together, e.g. , knotted by a conventional surgical knot, penetrating the tissue contiguous with the opening in the skin after the device is properly seated within the puncture to aid in holding or locking the device in place.
- the deployment instrument basically comprises an elongated tube or carrier 64 having an open distal free end 66 and a plunger assembly 68 located at the proximal end.
- the device 20 is disposed within the hollow interior of the carrier tube 64 adjacent its open free end 66, with the anchoring member 38 located immediately adjacent the free end and oriented so that its longitudinal axis is parallel to the longitudinal axis of the carrier tube.
- the sealing member is located immediately proximally of the anchoring member, and the holding member is located immediately proximally of the sealing member.
- the plunger assembly comprises a cylindrical cap 70 having a central passageway 72 extending therethrough in axial alignment and communicating with the interior of the tube 64.
- An elongated, cylindrical plunger 74 is located within the passageway 72 in the cap 70.
- the proximal end of the plunger is in the form of an enlarged head or button 76.
- An annular recess 78 is provided about the periphery of the plunger.
- a pair of diametrically opposed nibs 80 (Fig. 10) project from the inner surface of the cap into the annular recess to hold the plunger in a retracted, "ready" position as shown in Fig. 1.
- a longitudinally oriented slot 82 (Fig. 11) is provided in the carrier tube 64 adjacent the cap 70 to enable the ends 42A and 42B of the filament to extend out of the deployment instrument.
- a tamping member 84 in the form of an elongated sleeve, is disposed within the hollow interior of the carrier tube 64 between the holding member 40 and the distal end of the plunger 74.
- the sleeve includes a thin slot 86 (Fig. 12) extending along the length of the sleeve.
- the tamping member being an elongated sleeve includes a central passageway extending fully therethrough. The end portions 42A and 42B of the filament are arranged to extend through the central passageway in the tamping member 84, as shown clearly in Figs. 1 and 2.
- the trocar 34 basically comprises an elongated tube or sheath 88 formed of any suitable material, e.g., stainless steel.
- the sheath has an open distal end and a valve assembly 90 located at its proximal end.
- the valve assembly 90 includes any suitable valve member 92 to enable the deployment instrument to be inserted therethrough, as shown in Figs. 1 and 2.
- the device 20 of the subject invention is arranged to be used after the minimally invasive interventional procedure (e.g., laparoscopic, endoscopic, arthroscopic, procedure) is finished to seal the opening to prevent the passage of tissue or fluid therethrough and to enhance the long-term strength of the scar tissue which will naturally form at the opening 26 of the puncture 22 formed during the interventional procedure.
- the physician inserts the delivery or deployment instrument 32 containing the device 20 into the trocar 34 so that the distal end of the deployment instrument is extended through the opening 26 in the tissue wall as shown in Fig. 1.
- the plunger 74 of the deployment instrument is then depressed by pressing on its head or button 76 to release it from the ready position of Fig. 1 and move it distally, as shown in Fig. 2.
- This action causes the distal end of the plunger 74 to push on the proximal end of the tamping member 84, thereby moving the tamping member distally.
- This action pushes on the holding member 40, the sealing member 36, and the anchoring member 38, to cause the anchoring member to pass out of the distal end of the instrument and trocar sheath, thereby deploying the anchoring member into the abdominal cavity.
- the deployment instrument and trocar are then withdrawn from the puncture 22.
- This withdrawing action causes the anchoring member 38 to engage (e.g., catch) on the peritoneal wall contiguous with the opening 26.
- Continued withdrawal of the instrument and trocar deposit the sealing member 36, the holding member 40, and the distal end of the tamping member 84 of the deployment instrument into the puncture tract, as shown in Fig. 3.
- the tamping member is then grasped and gently pushed or tamped repeatedly into the puncture tract to push on the holding member. At the same time the free end of the filament 42 is pulled in the proximal direction. This combined action is shown in Fig.
- the knot 62 on the filament 42 adjacent the end portion 42A serves to hold the holding member 40 against the proximal end of the deformed sealing member.
- the sealing member is formed of compressed collagen (or other hydrolytic material) it expands automatically in the presence of blood or body fluids within the puncture tract when deployed, thereby further contributing to its deformation, e.g., enlargement, within the puncture tract.
- the expansion/deformation of the sealing member serves to aid in securing the device 20 in place.
- the deformation/expansion of the sealing means will serve as the only or primary means for securing the device in place within the puncture.
- the holding means 40 may be constructed like the compressible disk locking mechanism of the intravascular puncture closure disclosed in copending United States Patent Application, Serial No. 08/072,293, filed on June 4, 1993, entitled A Hemostatic Vessel Puncture Closure With Filament Lock, which is assigned to the same assignee as this invention and whose disclosure is incorporated by reference herein.
- the puncture closure of that application includes an anchoring member, a sealing member or plug of collagen foam, the locking mechanism, and a filament.
- the filament connects the anchoring member located within the interior of an artery with the plug in the puncture tract in a pulley-like arrangement so that the plug is movable toward the anchoring member.
- the compressible disk locking mechanism is arranged to be actuated, e.g., compressed, within the puncture tract to engage the filament in such a manner that the plug is held in the puncture sealing position.
- the filament and the anchoring means of this invention can be constructed like those locking mechanism components of the aforementioned copending application, wherein the anchoring means includes a notched passageway through which the filament extends and the filament comprises a portion having plural projections or teeth thereon adapted to slide into the notched passageway of the anchoring means in one direction but resistant to sliding in the opposite direction.
- the sealing member when the sealing member is in place within the puncture tract as described above it has the effect of sealing the puncture tract from the flow of fluid therethrough, while also preventing tissue from gaining egress therethrough.
- the sealing member in the case of thoracic placement the sealing member will prevent ingress of air into or out of the thoracic cavity.
- the sealing member In the case of peritoneal placement the sealing member will prevent the egress of blood or some other body fluid out of the abdominal wall, while also preventing any tissue from gaining egress through the opening in the peritoneum.
- the tamping member 84 is then removed from the puncture tract 28. To that end the extending portions 42A and 42B of the filament 42 are slid through the tamping member's longitudinally extending slot 86, thereby freeing the tamping member from the device 20. The end portions 42A and 42B of the filament extending out of the puncture tract are then knotted together. In particular, using standard surgical techniques, the filament end 42B with the stainless steel needle 44 is used to suture the skin 30 surface contiguous with the puncture 22 to form a conventional surgical knot 94 and thereby secure the device in place.
- FIG. 14 there is shown an alternative embodiment 100 of a device constructed in accordance with the subject invention.
- the device 100 can be used in any of the applications as discussed with reference to the device 20, and can be deployed through any type of trocar, by any type of deployment instrument.
- Figs. 15 - 20 the device 100 is shown being deployed through a trocar 102, by a deployment instrument 104.
- a deployment instrument 104 For some applications it may not be necessary to utilize any trocar to effect the placement of the device 100 within the percutaneous puncture.
- the trocar 102 is a conventional device, e.g., one sold by Apple Medical Corp. of Bolton, MA., and basically comprises a hollow cap 102A from which a elongated tube or sheath 102B formed of any suitable material projects.
- the sheath is arranged to pass through the percutaneous puncture and terminates in an open distal end 102C communicating with the interior of the patient's body, e.g., the interior of the abdomen, when the trocar is in place.
- the trocar includes a hemostatic valve 102D located at within the hollow cap 102A. The valve is arranged to enable the deployment instrument 104 to be inserted therethrough, as shown in Fig. 15.
- Other conventional, or non-conventional type trocars can be used to enable the device 100 to be deployed into a puncture tract in accordance with this invention.
- the deployment instrument 104 is also a conventional device, e.g., a conventional "grasper" sold by various companies, and basically comprises a pair of pivotable jaws 104A and 104B at the distal end of the instrument and a pair of squeezable handles 104C and 104D mounted at the proximal end of the instrument. By squeezing the handles together the jaws close, whereas release of the handles causes the jaws to open.
- Other instruments can be used as deployment devices, as well, providing they include means for holding the anchoring member to enable it to be inserted through the percutaneous puncture and then released from the instrument so that the anchoring member can be retracted against the desired tissue, as will be described later.
- the device 100 basically comprises three components, namely, an anchoring member 106, a positioning filament 108, and a suturing member or needle 110.
- the anchoring member 106 is somewhat similar in construction to the anchoring members disclosed in the aforementioned United States Patent Applications and United States Patent No. 5,021,059 assigned to the same assignee as the subject invention, and like the anchoring member 38 described heretofore is arranged to be seated inside the penetrated internal structure, e.g., the peritoneum, against the tissue thereof adjacent, e.g., contiguous with the opening 26 through which it had been introduced, as will be described later.
- the anchoring member 106 is an elongated, low-profile component which is, preferably, sufficiently rigid such that once it is in position within the abdomen (as will be described later) it is resistant to deformation to preclude it from bending to pass back through the opening in the peritoneum and through the contiguous puncture tract.
- the member 106 has a generally planar top surface 106A, a radially contoured bottom surface 106B and a peripheral side surface 106C. Each end of the member 106 is rounded and the side surface of the member tapers inward slightly from its top surface to its bottom surface to facilitate its removal of it from the mold making it.
- a dome-like projection 106D is located at the center of the top surface of the anchoring member, with the top of the dome being flatted.
- a longitudinally extending slot 106E extends through the dome 106D of the anchoring member 106 and the underlying portion of the anchoring member to the bottom surface of the anchoring member as shown in Figs. 14 - 20.
- a rod-like hub 106F (Figs. 15 - 20) extends transversely across the slot 106 and serves as the means for securing the filament to the anchoring member, as will be described later.
- the anchoring member 106 may be constructed of the same material as that of anchoring member 38. Alternatively, it can be constructed of a 100% polyglocolide in place of the 50-50 polylactide-coglycolide resorbable polymer disclosed earlier. Moreover, the anchoring member 106, like anchoring member 38, need not be resorbable at all. Thus, it is contemplated that the anchoring members of this invention be constructed of a non- resorbable material, such a TEFLON*.
- the anchoring member 106 shown herein does not include any reinforcing means, like that of anchoring member 38. However, it may, if desired, include such means, depending upon the application it is to be put. For example, if it is desired to reinforce the opening in the peritoneum to strengthen the scar tissue forming thereat, and thus lessen the likelihood that a hernia will form at that site at some time in the future, the sealing device may include the heretofore identified and described reinforcing means.
- one or more additives such as a radiopaque material, or hemostatic agent, or antibacterial agent, or an anti-adhesion agent, or any other biologically active ingredient, can be blended into or coated upon the anchoring member 102 or the filament member or any combination thereof.
- the filament 108 preferably comprises a very thin flexible member, e.g., a resorbable suture, which connects the anchoring member 106 to the suturing needle 110.
- a very thin flexible member e.g., a resorbable suture
- the distal end of the filament 108 is extended into the longitudinally extending slot 106E, wrapped about the hub 106F, and formed into a knot 108A.
- the proximal end of the filament is secured to the needle 110.
- the needle is arranged to be removed from the filament after the device 100 has been deployed and secured, as will be described later.
- the needle may be releasably secured to the filament, or the filament may be severable so that it can be cut or otherwise severed to remove the needle therefrom.
- the needle 110 may be of any shape and construction, e.g., a standard, conventional, curved stainless steel needle.
- the sealing device 100 is arranged to be used after the minimally invasive interventional procedure (e.g., laparoscopic, endoscopic, arthro ⁇ scopic, procedure) is finished.
- the minimally invasive interventional procedure e.g., laparoscopic, endoscopic, arthro ⁇ scopic, procedure
- it blocks the opening 26 in the peritoneum to reduce the risk of herniation in the short term. It may also reduce the long term risk of herniation, particularly if it includes reinforcing means, by enhancing the long-term strength of the scar tissue which will naturally form at the opening.
- the placement of the device 100 in the percutaneous puncture precludes air from gaining ingress into the thoracic cavity through the puncture tract.
- the use of the device 100 is as follows: with the trocar in place extending through the puncture so that its distal end 102C is within the abdomen, the physician utilizes the grasper 104 to grasp one end of the anchoring member 106 of the device 100 between its jaws 104A and 104B. The anchoring member is then inserted into the proximal end cap 102A of the trocar 102 through its valve 102D so that the anchor is within the interior of the sheath as shown in Fig. 15. The proximal portion of the filament 108 with the needle 110 thereon remains outside of the trocar, with the intermediate portion of the filament extending through the valve 102D.
- the grasper is then moved in the distal direction until the anchoring member and the jaws are fully within the abdomen, as shown in Fig. 16, whereupon the grasper's handles 104C and 104D are released. This action opens the jaws and releases the anchoring member from the grasper, as shown.
- the anchoring member being coupled to the trocar, is thus not free within the abdomen since the filament extends through the valve 102D and is trapped thereby.
- the handles of the grasper are then squeezed together, whereupon the jaws close.
- the grasper is then retracted out of the trocar, leaving the device 100 in the position shown in Fig. 17, i.e., with the anchoring portion within the abdomen, and the middle of the filament trapped between the now-closed valve 102D of the trocar.
- the proximal end of the filament 108 is then pulled in the proximal direction to draw the anchoring member 106 against the free end 102C of the trocar, to trap it thereon as shown in Fig. 18.
- the longitudinal axis of the anchoring member is oriented generally parallel to the peritoneum contiguous with the opening 26.
- the trocar and the anchoring member are moved or retracted proximally as a unit until the top surface of the anchoring member engages the inner surface of the peritoneum contiguous with the opening therein. At this time the domed portion 106D of the anchoring member enters into the opening 26. This action effectively traps the anchoring member across the opening 26. Once the trocar has been removed from the puncture the puncture closes somewhat.
- the trocar is then removed, i.e., slid off of the proximal end of the filament and needle, while tension is maintained on the filament to keep the anchoring member in position extending across the opening 26 in the peritoneum, with the domed portion within the opening, as shown in Fig. 19.
- the anchoring member 106 may completely cover the opening, thereby sealing the opening, or only partially cover it.
- the anchoring member is approximately 10 mm wide so that it will just fit within a 10 mm trocar.
- the needle 110 is then utilized to sew or suture the filament to the skin and underlying fascia contiguous with the puncture tract, thereby fixedly securing the device 100 in place, as shown in Fig. 20.
- the filament 108 may be sutured to any suitable tissue within the puncture tract below the skin using the attached needle 110.
- the puncture tract may be sutured closed at the skin by a separate conventional suture.
- the filament 108 may be arranged so that it includes two extending portions 108B and 108C, like shown in Fig.
- both extending portions 108B and 108C may include respective needles 110 thereon.
- the two extending portions can be secured to the skin or the underlying tissue in the puncture tract by suturing the extending portion 108B through that tissue using the attached needle and then knotting the two extending portions together using any conventional surgical technique.
- the filament 108 may be knotted to the hub 106A of the anchoring member 106 in such a manner so that a pair of end portions of the filament extend from the anchoring member 106 instead of only one as shown in Fig.
- one of the two end portions has the needle 110 secured to its free end.
- This alternative embodiment enables both of the filament ends to extend out of the puncture tract when the device is in place so that the surgeon may grasp both of the ends to knot them together when suturing the filament to the skin and/or underlying tissue to secure the sealing device 100 in place.
- the needle 110 is removed from the filament 108, completing the puncture sealing procedure.
- a fixing member to be described later
- Fig. 23 there is shown an alternative embodiment for achieving that end.
- the alternative embodiment is denoted by the reference numeral 200 and is identical to the embodiment 100 except for two features, namely, the use of the fixing member mentioned above, and the inclusion of pair of filament ends (to be described later) extending from the anchoring member 106.
- the method of using (deploying) the sealing device 200 is identical in most respects to the method of using the sealing device 100.
- the common components of devices 100 and 200 will be given the same reference numerals, and their structure and function will not be reiterated herein.
- the complete method of using the sealing device 200 will not be discussed in detail, and only those steps which differ from those described earlier with reference to the sealing device 100 will be discussed in detail.
- the sealing device 200 includes the heretofore identified anchoring member 106 and the filament 108.
- the filament 108 includes a pair of end portions 108B and 108C which extend from the knot 108A affixing the filament to the hub 106F of the anchoring member 106.
- the sealing device 200 includes the previously mentioned fixing member, identified by the reference numeral 202.
- the fixing member 202 is an elongated, substantially stiff member, which is preferably constructed similarly to the anchoring member 38 of the sealing device 20.
- the fixing member 202 includes a pair of apertures 54 and 56 through which the filament end portions 108B and 108C, respectively, extend.
- the free end of filament portion 108B includes the needle 110 mounted thereon.
- the sealing of the percutaneous puncture tract into the abdomen using the sealing device 200 is accomplished as follows: with the trocar in place extending through the puncture so that its distal end 102C is within the abdomen, the physician utilizes the grasper 104 to insert the anchoring member 106 into the interior of the sheath of the trocar as described earlier and as shown in Fig. 23.
- the proximal portion of the filament end 108B with the needle 110 thereon remains outside of the trocar, as does the free end of the filament portion 108C.
- the fixing member 202 is located outside of the trocar, and threaded on the filament portions 108B and 108C between the free ends thereof and the trocar.
- the anchoring member is then introduced into the abdomen and trapped against the interior of the peritoneum contiguous with the opening therein in the same manner as described heretofore.
- the trocar is then removed from the extending filament portions 108B and 108C, while tension is maintained on those filament portions to keep the anchoring member 106 in position extending across the opening 26 in the peritoneum 24, with its domed portion 106D within the peritoneum opening 26.
- the grasper 104 is used to grasp one end of the fixing member 202 between its jaws 104A and 104B, and the grasped fixing member is slid down the filament portions 108B and 108C so that it enters into the puncture tract 28, while tension is maintained on at least one (and preferably both) of the filament portions 108B and 108C as shown in Fig. 24. This action ensures that the anchoring member 106 remains trapped against the interior of the peritoneum over opening 26.
- the grasper 104 is manipulated to orient the fixing member so that the longitudinal axis of the fixing member is transverse to the longitudinal axis of the puncture tract.
- the grasper 104 is then operated to release the fixing member from its jaws, and to retract the grasper out of the puncture tract. Once this is accomplished the two end portions 108B and 108C of the filament 108, which are still under tension, are knotted together at 108G immediately proximally of the fixing member 202 as shown in Fig. 25. This action keeps the portions of the filament 108 between the anchoring member 106 and the locking member 202 in tension, with the anchoring member trapped on the inner surface of the peritoneum and closing the opening 26 therein, thereby securing the sealing device 200 in place.
- the needle 110 on the free end of the filament portion 108B can then be used to suture the puncture tract together using the filament portion 108B contiguous with the skin, or below the skin, depending upon the desires of the surgeon. This action effectively closes the puncture tract. Once that has been accomplished the needle 110 may be removed, as described earlier.
- the timing of the resorption of the resorbable components of the sealing devices 20, 100 and 200 can be controlled by various means, e.g., the higher the molecular weight of the resorbable polymer, the longer the material will take to resorb.
- the anchoring members 20 or 106 or any other resorbable portions of the devices 20, 100 and 200
- such components will have a longer resorption time than those of the 50-50 polylactide-co-glycolide mix, but should be more thermally stable during shipping.
- the sealing devices of the subject invention are not limited to protecting against the formation of a hernia at the site of a percutaneous puncture, but can be used to repair an existing hernia, as well.
- the existing hernia can be penetrated from the outside by means of any suitable piercing instrument, e.g., a conventional or non-conventional trocar, to form a percutaneous puncture through the herniated tissue.
- the anchoring member of the particular device may include elements on its top surface, i.e., the surface which engages the tissue.
- the anchoring member may include spikes, treads, or other projections on its top surface to engage the inner surface of the tissue having the opening being sealed, e.g., the peritoneum, to aid in securing the anchor in place and to hold the edges of the opening contiguous with each other.
- the sealing devices of the subject invention can be used to seal or close other percutaneous openings in internally located tissue, not only openings in the peritoneum, and to prevent the egress of tissue through the opening.
- the devices of the subject invention can be used to close an opening in the wall of the thoracic cavity or lung, a herniated opening in the diaphragm, etc.
- the anchoring member can be used to deliver a medication or a biologically acting material, e.g., an anti- adhesion drug may be coated on the anchoring member, an antibiotic or growth factor may be included in the anchoring member or coated thereon.
- the anchoring member may be made radio-opaque to facilitate its placement or location, and may be formed of a single or multi-components.
- FIGs. 26 - 28 there are shown alternative embodiments of anchoring members for the sealing devices of this invention.
- the anchoring members of these figures all share a common feature, namely, the inclusion of one or more apertures or holes extending transversely through the plane of the anchoring member, i.e., between its top surface and its bottom surface.
- These apertures or holes form voids into which tissue may grow when the anchoring member is in place as described earlier, thereby facilitating the securement of the sealing device in place.
- fibroblast intrusions into the voids in the anchoring member should more readily tend to engage the anchoring member securely to the tissue at the puncture site until the puncture heals.
- Another advantage of the use of apertures or voids in an anchoring member is a reduction in the resorption time of the member.
- Figs. 26 and 27 there are shown alternative embodiments 38' and 38", respectively, of the anchoring member 38 described heretofore.
- the only differences in the construction of member 38' and 38" from the member 38 is the inclusion of a plurality of apertures or holes therein.
- the anchoring member 38' includes a plurality of apertures 96 extending through the body of the anchoring member from its top surface to its bottom surface. In the embodiment shown these apertures are square in shape, but that construction is merely exemplary.
- FIG. 27 there is shown the anchoring embodiment 38", which includes only two apertures or holes 98 extending through the body of the anchoring member from its top surface to its bottom surface.
- the apertures 98 are large, and each is of irregular shape generally corresponding to the periphery of the anchoring member.
- the anchoring member may be constructed like the embodiment 106' shown in Fig. 28.
- the embodiment 106' constitutes an alternative to the embodiment 106 described above.
- the only difference in the construction of anchoring member 106' from the member 106 is the inclusion of a pair of apertures or holes 96 therein.
- the common features of the anchoring members 106 and 106' will be given the same reference numbers, and their construction and operation will not be reiterated.
- the apertures 96 in anchoring member 106' are constructed like those described above, but may be of alternative shape, size, and number, as also described above, e.g., may be like apertures 98.
- the apertures to create the tissue ingrowth voids in the anchoring members of this invention need not extend fully through the anchoring member, like apertures 96 and 98, but may only extend partially into the body of the anchoring member, e.g. , the voids may be in the form of recesses, grooves, slots, cavities, etc., or other shapes, undercut or otherwise, forming space(s) into which the tissue at the puncture site may grow.
- the anchoring member and filament shown and described heretofore are described as being separate components which are secured together, it should be apparent that they may be formed as a unitary member, e.g., molded as a unit of a resorbable material like described above. In fact the needle may be molded integrally with the filament and anchoring member.
- the anchoring member 106 (and for that matter member 106') includes a slot 106E in the dome portion thereof.
- This slot provides a passageway through which liquids or gasses may flow when the anchoring member is in place.
- the slot may be utilized to enable the passage of C0 2 from the abdominal cavity out of the body, thereby helping to avoid trapping gas in the patient after the laparoscopic procedure is over.
- the central portion of anchoring which covers or fills the opening in the tissue may be unapertured, e.g., the slot eliminated, or constructed so that it does not extend from the top to the bottom of the anchoring member.
- the slot may be made sufficiently small that it is fully filled by the filament portion extending therein and about the hub 106F so that gas remains trapped within the patient.
- the anchoring means is preferably constructed in any of these alternative manners so that there is not passageway through which air can leak in to the thoracic cavity from the ambient surroundings through the anchoring member.
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95918857A EP0759725A1 (en) | 1994-04-29 | 1995-04-27 | System for closing a percutaneous trocar puncture |
JP7528367A JPH09512461A (en) | 1994-04-29 | 1995-04-27 | Percutaneous trocar puncture closure system |
AU24620/95A AU2462095A (en) | 1994-04-29 | 1995-04-27 | System for closing a percutaneous trocar puncture |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/235,825 US5531759A (en) | 1994-04-29 | 1994-04-29 | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
US08/235,825 | 1994-10-21 | ||
US08/327,262 | 1994-10-21 | ||
US08/327,262 US5545178A (en) | 1994-04-29 | 1994-10-21 | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995029635A1 true WO1995029635A1 (en) | 1995-11-09 |
Family
ID=26929255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/005187 WO1995029635A1 (en) | 1994-04-29 | 1995-04-27 | System for closing a percutaneous trocar puncture |
Country Status (6)
Country | Link |
---|---|
US (1) | US5545178A (en) |
EP (1) | EP0759725A1 (en) |
JP (1) | JPH09512461A (en) |
AU (1) | AU2462095A (en) |
CA (1) | CA2188751A1 (en) |
WO (1) | WO1995029635A1 (en) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998040017A3 (en) * | 1997-03-12 | 1998-10-22 | Advanced Closure Systems Inc | Vascular sealing device |
WO1998040016A3 (en) * | 1997-03-12 | 1998-10-29 | Advanced Closure Systems Inc | Universal introducer |
DE10027186A1 (en) * | 2000-05-31 | 2001-12-20 | Aesculap Ag & Co Kg | Device for closing an opening in a fabric layer |
DE10310995B3 (en) * | 2003-03-06 | 2004-09-16 | Aesculap Ag & Co. Kg | Closure device for a puncture channel and applicator device |
US7828854B2 (en) | 2006-10-31 | 2010-11-09 | Ethicon, Inc. | Implantable repair device |
US7857823B2 (en) | 1999-06-22 | 2010-12-28 | Ethicon Endo-Surgery, Inc. | Tissue reconfiguration |
US8057494B2 (en) | 1999-06-22 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Methods and devices for tissue reconfiguration |
WO2012018454A1 (en) | 2010-08-03 | 2012-02-09 | Gore Enterprise Holdings, Inc. | Tissue plug |
US8221452B2 (en) | 1997-03-12 | 2012-07-17 | Neomend, Inc. | Systems and methods for sealing a vascular puncture |
US8241323B2 (en) | 2006-09-07 | 2012-08-14 | Terumo Kabushiki Kaisha | Tissue closing device |
WO2012158931A1 (en) * | 2011-05-19 | 2012-11-22 | St. Jude Medical Puerto Rico Llc | Procedural sheath adapter for vascular closure device |
US8500759B2 (en) | 2007-09-26 | 2013-08-06 | Ethicon, Inc. | Hernia mesh support device |
WO2014028166A1 (en) * | 2012-08-15 | 2014-02-20 | St. Jude Medical Puerto Rico Llc | Vascular closure device anchor |
US8852216B2 (en) | 2007-03-23 | 2014-10-07 | Ethicon Endo-Surgery, Inc. | Tissue approximation methods |
US8888812B2 (en) | 2000-12-14 | 2014-11-18 | Cordis Corporation | Plug with collet and apparatus and methods for delivering such plugs |
US10098620B2 (en) | 2010-07-12 | 2018-10-16 | Terumo Puerto Rico, L.L.C. | Compactionless tissue puncture closure device and methods |
EP3556297A1 (en) * | 2010-05-19 | 2019-10-23 | Cook Medical Technologies, LLC | Devices for sealing bodily openings |
FR3091988A1 (en) * | 2019-01-29 | 2020-07-31 | Advance | INSTRUMENTATION ALLOWING THE PLACEMENT, IN A BONE OR OTHER BODY TISSUE, OF AN ANCHOR CONNECTED TO AT LEAST ONE SUTURE WIRE |
EP3025653B1 (en) * | 2006-06-21 | 2021-06-16 | Cook Biotech Incorporated | Fistula grafts useful for treating gastrointestinal fistulae |
Families Citing this family (492)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6036699A (en) | 1992-12-10 | 2000-03-14 | Perclose, Inc. | Device and method for suturing tissue |
US6355050B1 (en) | 1992-12-10 | 2002-03-12 | Abbott Laboratories | Device and method for suturing tissue |
US5549630A (en) * | 1993-05-14 | 1996-08-27 | Bonutti; Peter M. | Method and apparatus for anchoring a suture |
US6383199B2 (en) * | 1993-08-25 | 2002-05-07 | Inlet Medical, Inc. | Devices for investing within ligaments for retracting and reinforcing the same |
US5527322A (en) | 1993-11-08 | 1996-06-18 | Perclose, Inc. | Device and method for suturing of internal puncture sites |
US5569303A (en) * | 1994-10-18 | 1996-10-29 | Johnson; Lanny L. | Apparatus and method for attaching an object to bone |
US5810846A (en) * | 1995-08-03 | 1998-09-22 | United States Surgical Corporation | Vascular hole closure |
US6071301A (en) * | 1998-05-01 | 2000-06-06 | Sub Q., Inc. | Device and method for facilitating hemostasis of a biopsy tract |
US6183497B1 (en) | 1998-05-01 | 2001-02-06 | Sub-Q, Inc. | Absorbable sponge with contrasting agent |
US6162192A (en) * | 1998-05-01 | 2000-12-19 | Sub Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US6524326B1 (en) | 1995-12-07 | 2003-02-25 | Loma Linda University Medical Center | Tissue opening locator and everter and method |
US6287322B1 (en) | 1995-12-07 | 2001-09-11 | Loma Linda University Medical Center | Tissue opening locator and everter and method |
US6004341A (en) * | 1996-12-05 | 1999-12-21 | Loma Linda University Medical Center | Vascular wound closure device |
US6007567A (en) * | 1996-08-19 | 1999-12-28 | Bonutti; Peter M. | Suture anchor |
US5718717A (en) * | 1996-08-19 | 1998-02-17 | Bonutti; Peter M. | Suture anchor |
US5810884A (en) * | 1996-09-09 | 1998-09-22 | Beth Israel Deaconess Medical Center | Apparatus and method for closing a vascular perforation after percutaneous puncture of a blood vessel in a living subject |
US5827291A (en) * | 1996-11-05 | 1998-10-27 | Linvatec Corporation | Suture anchor driver with suture retainer |
CA2271029C (en) * | 1996-11-18 | 2006-01-10 | University Of Massachusetts | Systems, methods, and instruments for minimally invasive surgery |
US6165184A (en) * | 1996-11-18 | 2000-12-26 | Smith & Nephew, Inc. | Systems methods and instruments for minimally invasive surgery |
EP0996369A1 (en) * | 1997-01-21 | 2000-05-03 | Quinton Instrument Company | Hemostasis promoting device for sealing a puncture in a patient |
US5984948A (en) * | 1997-04-14 | 1999-11-16 | Hasson; Harrith M. | Device for closing an opening in tissue and method of closing a tissue opening using the device |
US5830232A (en) * | 1997-04-14 | 1998-11-03 | Hasson; Harrith M. | Device for closing an opening in tissue and method of closing a tissue opening using the device |
US6056762A (en) | 1997-05-22 | 2000-05-02 | Kensey Nash Corporation | Anastomosis system and method of use |
US6066776A (en) * | 1997-07-16 | 2000-05-23 | Atrium Medical Corporation | Self-forming prosthesis for repair of soft tissue defects |
EP0895753A1 (en) * | 1997-07-31 | 1999-02-10 | Academisch Ziekenhuis Utrecht | Temporary vascular seal for anastomosis |
US6063114A (en) * | 1997-09-04 | 2000-05-16 | Kensey Nash Corporation | Connector system for vessels, ducts, lumens or hollow organs and methods of use |
FR2774580B1 (en) * | 1998-02-06 | 2000-09-08 | Laurent Fumex | BONE ANCHORING SURGICAL DEVICE |
US6045551A (en) | 1998-02-06 | 2000-04-04 | Bonutti; Peter M. | Bone suture |
US20010045575A1 (en) | 1998-05-01 | 2001-11-29 | Mark Ashby | Device and method for facilitating hemostasis of a biopsy tract |
US6315753B1 (en) | 1998-05-01 | 2001-11-13 | Sub-Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US6200328B1 (en) | 1998-05-01 | 2001-03-13 | Sub Q, Incorporated | Device and method for facilitating hemostasis of a biopsy tract |
US6610026B2 (en) | 1998-05-01 | 2003-08-26 | Sub-Q, Inc. | Method of hydrating a sponge material for delivery to a body |
US5910155A (en) * | 1998-06-05 | 1999-06-08 | United States Surgical Corporation | Vascular wound closure system |
EP1051116B8 (en) | 1998-12-01 | 2009-06-10 | Washington University | Embolization device |
AU2045200A (en) * | 1998-12-08 | 2000-06-26 | University Of Virginia Patent Foundation | Device and technique for percutaneous closure of vascular puncture sites |
ATE324072T1 (en) | 1998-12-30 | 2006-05-15 | Ethicon Inc | THREAD SECURING DEVICE |
EP1156741B1 (en) | 1999-02-10 | 2010-12-22 | Sub-Q, Inc. | Device for facilitating hemostasis of a biopsy tract |
US7842048B2 (en) | 2006-08-18 | 2010-11-30 | Abbott Laboratories | Articulating suture device and method |
US7235087B2 (en) | 1999-03-04 | 2007-06-26 | Abbott Park | Articulating suturing device and method |
US6964668B2 (en) | 1999-03-04 | 2005-11-15 | Abbott Laboratories | Articulating suturing device and method |
US7001400B1 (en) | 1999-03-04 | 2006-02-21 | Abbott Laboratories | Articulating suturing device and method |
US20040092964A1 (en) | 1999-03-04 | 2004-05-13 | Modesitt D. Bruce | Articulating suturing device and method |
US8137364B2 (en) | 2003-09-11 | 2012-03-20 | Abbott Laboratories | Articulating suturing device and method |
US6689153B1 (en) | 1999-04-16 | 2004-02-10 | Orthopaedic Biosystems Ltd, Inc. | Methods and apparatus for a coated anchoring device and/or suture |
US6258124B1 (en) * | 1999-05-10 | 2001-07-10 | C. R. Bard, Inc. | Prosthetic repair fabric |
US6488689B1 (en) | 1999-05-20 | 2002-12-03 | Aaron V. Kaplan | Methods and apparatus for transpericardial left atrial appendage closure |
US20070038231A1 (en) | 1999-05-28 | 2007-02-15 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
US20060247665A1 (en) | 1999-05-28 | 2006-11-02 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
US7273497B2 (en) | 1999-05-28 | 2007-09-25 | Anova Corp. | Methods for treating a defect in the annulus fibrosis |
US7416554B2 (en) | 2002-12-11 | 2008-08-26 | Usgi Medical Inc | Apparatus and methods for forming and securing gastrointestinal tissue folds |
US6497650B1 (en) * | 1999-07-28 | 2002-12-24 | C. R. Bard, Inc. | Hernia prosthesis |
US6368343B1 (en) | 2000-03-13 | 2002-04-09 | Peter M. Bonutti | Method of using ultrasonic vibration to secure body tissue |
US6447516B1 (en) | 1999-08-09 | 2002-09-10 | Peter M. Bonutti | Method of securing tissue |
JP4247519B2 (en) | 1999-08-18 | 2009-04-02 | イントリンジック セラピューティックス インコーポレイテッド | Apparatus and method for nucleus augmentation and retention |
US7998213B2 (en) * | 1999-08-18 | 2011-08-16 | Intrinsic Therapeutics, Inc. | Intervertebral disc herniation repair |
US7553329B2 (en) | 1999-08-18 | 2009-06-30 | Intrinsic Therapeutics, Inc. | Stabilized intervertebral disc barrier |
WO2009033100A1 (en) | 2007-09-07 | 2009-03-12 | Intrinsic Therapeutics, Inc. | Bone anchoring systems |
US8323341B2 (en) | 2007-09-07 | 2012-12-04 | Intrinsic Therapeutics, Inc. | Impaction grafting for vertebral fusion |
US7717961B2 (en) | 1999-08-18 | 2010-05-18 | Intrinsic Therapeutics, Inc. | Apparatus delivery in an intervertebral disc |
US7972337B2 (en) | 2005-12-28 | 2011-07-05 | Intrinsic Therapeutics, Inc. | Devices and methods for bone anchoring |
US7220281B2 (en) | 1999-08-18 | 2007-05-22 | Intrinsic Therapeutics, Inc. | Implant for reinforcing and annulus fibrosis |
US6425919B1 (en) | 1999-08-18 | 2002-07-30 | Intrinsic Orthopedics, Inc. | Devices and methods of vertebral disc augmentation |
WO2004100841A1 (en) | 1999-08-18 | 2004-11-25 | Intrinsic Therapeutics, Inc. | Devices and method for augmenting a vertebral disc nucleus |
US20040010317A1 (en) | 1999-08-18 | 2004-01-15 | Gregory Lambrecht | Devices and method for augmenting a vertebral disc |
US7942888B2 (en) | 1999-09-13 | 2011-05-17 | Rex Medical, L.P. | Vascular hole closure device |
US7267679B2 (en) * | 1999-09-13 | 2007-09-11 | Rex Medical, L.P | Vascular hole closure device |
AU7373700A (en) * | 1999-09-13 | 2001-04-17 | Rex Medical, Lp | Vascular closure |
US8083766B2 (en) | 1999-09-13 | 2011-12-27 | Rex Medical, Lp | Septal defect closure device |
US7662161B2 (en) | 1999-09-13 | 2010-02-16 | Rex Medical, L.P | Vascular hole closure device |
US7341595B2 (en) | 1999-09-13 | 2008-03-11 | Rex Medical, L.P | Vascular hole closure device |
US6358258B1 (en) | 1999-09-14 | 2002-03-19 | Abbott Laboratories | Device and method for performing end-to-side anastomosis |
US6190396B1 (en) | 1999-09-14 | 2001-02-20 | Perclose, Inc. | Device and method for deploying and organizing sutures for anastomotic and other attachments |
US7695492B1 (en) | 1999-09-23 | 2010-04-13 | Boston Scientific Scimed, Inc. | Enhanced bleed back system |
US7004970B2 (en) | 1999-10-20 | 2006-02-28 | Anulex Technologies, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
US7615076B2 (en) | 1999-10-20 | 2009-11-10 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7052516B2 (en) | 1999-10-20 | 2006-05-30 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and deformable spinal disc annulus stent |
US8128698B2 (en) | 1999-10-20 | 2012-03-06 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7951201B2 (en) | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
US6592625B2 (en) * | 1999-10-20 | 2003-07-15 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
US7935147B2 (en) | 1999-10-20 | 2011-05-03 | Anulex Technologies, Inc. | Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus |
US7887551B2 (en) | 1999-12-02 | 2011-02-15 | Smith & Nephew, Inc. | Soft tissue attachment and repair |
US7153312B1 (en) | 1999-12-02 | 2006-12-26 | Smith & Nephew Inc. | Closure device and method for tissue repair |
US8758400B2 (en) | 2000-01-05 | 2014-06-24 | Integrated Vascular Systems, Inc. | Closure system and methods of use |
US6635073B2 (en) | 2000-05-03 | 2003-10-21 | Peter M. Bonutti | Method of securing body tissue |
CN1226019C (en) * | 2000-02-24 | 2005-11-09 | 洛马林达大学医学中心 | Patch and glue delivery system for closing tissue openings during surgery |
US9138222B2 (en) | 2000-03-13 | 2015-09-22 | P Tech, Llc | Method and device for securing body tissue |
US7094251B2 (en) | 2002-08-27 | 2006-08-22 | Marctec, Llc. | Apparatus and method for securing a suture |
US6425924B1 (en) | 2000-03-31 | 2002-07-30 | Ethicon, Inc. | Hernia repair prosthesis |
US6805695B2 (en) | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
AU2001253461A1 (en) * | 2000-04-14 | 2001-10-30 | Orthopaedic Biosystems Ltd., Inc. | Coated anchoring device |
US6786915B2 (en) * | 2000-04-19 | 2004-09-07 | Radi Medical Systems Ab | Reinforced absorbable medical sealing device |
US6540735B1 (en) | 2000-05-12 | 2003-04-01 | Sub-Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US6558399B1 (en) | 2000-06-30 | 2003-05-06 | Abbott Laboratories | Devices and method for handling a plurality of suture elements during a suturing procedure |
AU2001273401A1 (en) * | 2000-07-14 | 2002-01-30 | Sub-Q Inc. | Sheath-mounted arterial plug delivery device |
US6890342B2 (en) | 2000-08-02 | 2005-05-10 | Loma Linda University | Method and apparatus for closing vascular puncture using hemostatic material |
AU8800801A (en) | 2000-09-08 | 2002-03-22 | James E Coleman | Surgical staple |
US7404819B1 (en) | 2000-09-14 | 2008-07-29 | C.R. Bard, Inc. | Implantable prosthesis |
US7201725B1 (en) | 2000-09-25 | 2007-04-10 | Sub-Q, Inc. | Device and method for determining a depth of an incision |
US6730102B1 (en) | 2000-11-06 | 2004-05-04 | Abbott Laboratories | Systems, devices and methods for deploying needles |
US8690910B2 (en) | 2000-12-07 | 2014-04-08 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US6695867B2 (en) | 2002-02-21 | 2004-02-24 | Integrated Vascular Systems, Inc. | Plunger apparatus and methods for delivering a closure device |
US6623510B2 (en) | 2000-12-07 | 2003-09-23 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US8083768B2 (en) * | 2000-12-14 | 2011-12-27 | Ensure Medical, Inc. | Vascular plug having composite construction |
AU2002238076B2 (en) * | 2001-02-09 | 2007-05-17 | Endoluminal Therapeutics, Inc. | Endomural therapy |
WO2002087636A1 (en) * | 2001-03-12 | 2002-11-07 | Sub-Q, Inc. | Methods for sterilizing cross-linked gelatin compositions |
US20030163161A1 (en) * | 2001-03-12 | 2003-08-28 | Barron John Christopher | Bone anchor protective cover |
US8187625B2 (en) | 2001-03-12 | 2012-05-29 | Boston Scientific Scimed, Inc. | Cross-linked gelatin composition comprising a wetting agent |
US8202315B2 (en) | 2001-04-24 | 2012-06-19 | Mitralign, Inc. | Catheter-based annuloplasty using ventricularly positioned catheter |
US20060069429A1 (en) * | 2001-04-24 | 2006-03-30 | Spence Paul A | Tissue fastening systems and methods utilizing magnetic guidance |
US6619291B2 (en) * | 2001-04-24 | 2003-09-16 | Edwin J. Hlavka | Method and apparatus for catheter-based annuloplasty |
US7029489B1 (en) | 2001-05-18 | 2006-04-18 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture site |
US20060004408A1 (en) * | 2001-06-08 | 2006-01-05 | Morris Edward J | Method and apparatus for sealing access |
US7993365B2 (en) * | 2001-06-08 | 2011-08-09 | Morris Innovative, Inc. | Method and apparatus for sealing access |
US20070038244A1 (en) * | 2001-06-08 | 2007-02-15 | Morris Edward J | Method and apparatus for sealing access |
US6712859B2 (en) | 2001-06-28 | 2004-03-30 | Ethicon, Inc. | Hernia repair prosthesis and methods for making same |
AU2002354911B2 (en) | 2001-07-16 | 2007-08-30 | Depuy Products, Inc. | Meniscus regeneration device and method |
US7819918B2 (en) | 2001-07-16 | 2010-10-26 | Depuy Products, Inc. | Implantable tissue repair device |
AU2002322567B2 (en) * | 2001-07-16 | 2007-09-06 | Depuy Products, Inc. | Devices form naturally occurring biologically derived |
EP1416874A4 (en) | 2001-07-16 | 2007-04-18 | Depuy Products Inc | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
WO2003007787A2 (en) * | 2001-07-16 | 2003-01-30 | Depuy Products, Inc. | Cartilage repair and regeneration device and method |
AU2002354913B2 (en) | 2001-07-16 | 2008-07-17 | Depuy Products, Inc. | Unitary surgical device and method |
US8465516B2 (en) * | 2001-07-26 | 2013-06-18 | Oregon Health Science University | Bodily lumen closure apparatus and method |
JP4180509B2 (en) * | 2001-07-26 | 2008-11-12 | ウイルソンークック メディカル インク. | Vessel occlusion member and distribution device thereof |
ES2183736B1 (en) * | 2001-08-03 | 2004-06-16 | Bard De España, S.A. | IMPLANTABLE WALL PROTESIS IN THE FOCUS OF THE WOUND FOR REINFORCEMENT OF ABDOMINAL WALL CLOSURE. |
US7037322B1 (en) | 2001-11-08 | 2006-05-02 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture with a staging tube |
US6719765B2 (en) | 2001-12-03 | 2004-04-13 | Bonutti 2003 Trust-A | Magnetic suturing system and method |
US6746457B2 (en) * | 2001-12-07 | 2004-06-08 | Abbott Laboratories | Snared suture trimmer |
US8211123B2 (en) | 2001-12-21 | 2012-07-03 | Abbott Laboratories | Suture trimmer |
US6814743B2 (en) | 2001-12-26 | 2004-11-09 | Origin Medsystems, Inc. | Temporary seal and method for facilitating anastomosis |
US6790213B2 (en) | 2002-01-07 | 2004-09-14 | C.R. Bard, Inc. | Implantable prosthesis |
US6966887B1 (en) | 2002-02-27 | 2005-11-22 | Origin Medsystems, Inc. | Temporary arterial shunt and method |
EP1482841B1 (en) | 2002-03-14 | 2005-12-07 | Yeung, Jeffery E. | Suture anchor and approximating device |
US9155544B2 (en) | 2002-03-20 | 2015-10-13 | P Tech, Llc | Robotic systems and methods |
US6755868B2 (en) | 2002-03-22 | 2004-06-29 | Ethicon, Inc. | Hernia repair device |
US7850709B2 (en) | 2002-06-04 | 2010-12-14 | Abbott Vascular Inc. | Blood vessel closure clip and delivery device |
DE60309030T2 (en) | 2002-06-14 | 2007-05-16 | Loma Linda University Medical Center, Loma Linda | DEVICE FOR CLOSING VESSEL WALLS |
AU2003253330A1 (en) | 2002-08-01 | 2004-02-23 | Abbott Laboratories Vascular Enterprises, Limited | Autologous wound sealing apparatus |
EP1538989B1 (en) * | 2002-08-01 | 2010-03-17 | Abbott Laboratories Vascular Enterprises Limited | Apparatus for sealing punctures in blood vessels |
US7101381B2 (en) * | 2002-08-02 | 2006-09-05 | C.R. Bard, Inc. | Implantable prosthesis |
US20050119735A1 (en) | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
NZ539136A (en) * | 2002-10-21 | 2008-04-30 | Mitralign Inc | Method and apparatus for performing catheter-based annuloplasty using local plications |
US20040102730A1 (en) * | 2002-10-22 | 2004-05-27 | Davis Thomas P. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US7955353B1 (en) | 2002-11-04 | 2011-06-07 | Sub-Q, Inc. | Dissolvable closure device |
US7455680B1 (en) | 2002-11-04 | 2008-11-25 | Boston Scientific Scimed, Inc. | Apparatus and method for inhibiting blood loss |
US8317821B1 (en) | 2002-11-04 | 2012-11-27 | Boston Scientific Scimed, Inc. | Release mechanism |
US7942898B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Delivery systems and methods for gastric reduction |
US7942884B2 (en) | 2002-12-11 | 2011-05-17 | Usgi Medical, Inc. | Methods for reduction of a gastric lumen |
US7160309B2 (en) | 2002-12-31 | 2007-01-09 | Laveille Kao Voss | Systems for anchoring a medical device in a body lumen |
GB0300786D0 (en) * | 2003-01-14 | 2003-02-12 | Barker Stephen G E | Laparoscopic port hernia device |
EP1440656A3 (en) * | 2003-01-14 | 2004-10-06 | Radi Medical Systems Ab | Device for visually indicating a blood pressure |
US8398656B2 (en) | 2003-01-30 | 2013-03-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8202293B2 (en) | 2003-01-30 | 2012-06-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US9314235B2 (en) | 2003-02-05 | 2016-04-19 | Smith & Nephew, Inc. | Tissue anchor and insertion tool |
US7497864B2 (en) | 2003-04-30 | 2009-03-03 | Marctec, Llc. | Tissue fastener and methods for using same |
US20040260300A1 (en) | 2003-06-20 | 2004-12-23 | Bogomir Gorensek | Method of delivering an implant through an annular defect in an intervertebral disc |
DK1638485T3 (en) | 2003-06-20 | 2011-05-02 | Intrinsic Therapeutics Inc | Device for delivery of an implant through an annular defect in an intervertebral disc |
US20050049634A1 (en) * | 2003-08-07 | 2005-03-03 | Scimed Life Systems, Inc. | Medical closure device |
AU2004266574B2 (en) | 2003-08-13 | 2010-11-04 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compressive device for percutaneous treatment of obesity |
CA2535452C (en) | 2003-08-14 | 2013-04-02 | Loma Linda University Medical Center | Vascular wound closure device |
US8187627B2 (en) * | 2003-09-05 | 2012-05-29 | Loma Linda University Medical Center | Dressing delivery system for internal wounds |
US7462188B2 (en) | 2003-09-26 | 2008-12-09 | Abbott Laboratories | Device and method for suturing intracardiac defects |
EP1682034B1 (en) | 2003-10-09 | 2018-11-21 | Sentreheart, Inc. | Apparatus for the ligation of tissue |
US7931670B2 (en) * | 2003-10-15 | 2011-04-26 | St. Jude Medical Puerto Rico Llc | Tissue puncture closure device with automatic tamping |
US8337522B2 (en) * | 2003-10-15 | 2012-12-25 | St. Jude Medical Puerto Rico Llc | Vascular sealing device with locking hub |
US20050096696A1 (en) * | 2003-11-04 | 2005-05-05 | Forsberg Andrew T. | Arteriotomy closure device with anti-roll anchor |
US8128652B2 (en) * | 2003-11-13 | 2012-03-06 | St. Jude Medical Puerto Rico Llc | Method and apparatus for sealing an internal tissue puncture incorporating a block and tackle |
WO2005051176A2 (en) * | 2003-11-25 | 2005-06-09 | Boston Scientific Limited | Hemostatic pressure plug |
US7597705B2 (en) * | 2003-12-03 | 2009-10-06 | St. Jude Medical Puerto Rico Llc | Vascular puncture seal anchor nest |
US7621937B2 (en) | 2003-12-03 | 2009-11-24 | St. Jude Medical Puerto Rico LC | Vascular sealing device with high surface area sealing plug |
US7875043B1 (en) | 2003-12-09 | 2011-01-25 | Sub-Q, Inc. | Cinching loop |
US8864822B2 (en) * | 2003-12-23 | 2014-10-21 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
US7166127B2 (en) * | 2003-12-23 | 2007-01-23 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
US7449024B2 (en) | 2003-12-23 | 2008-11-11 | Abbott Laboratories | Suturing device with split arm and method of suturing tissue |
US7608092B1 (en) | 2004-02-20 | 2009-10-27 | Biomet Sports Medicince, LLC | Method and apparatus for performing meniscus repair |
US20080039873A1 (en) | 2004-03-09 | 2008-02-14 | Marctec, Llc. | Method and device for securing body tissue |
US7569233B2 (en) | 2004-05-04 | 2009-08-04 | Depuy Products, Inc. | Hybrid biologic-synthetic bioabsorbable scaffolds |
US20050267521A1 (en) * | 2004-05-13 | 2005-12-01 | St. Jude Medical Puerto Rico B.V. | Collagen sponge for arterial sealing |
US9463012B2 (en) | 2004-10-26 | 2016-10-11 | P Tech, Llc | Apparatus for guiding and positioning an implant |
US9271766B2 (en) | 2004-10-26 | 2016-03-01 | P Tech, Llc | Devices and methods for stabilizing tissue and implants |
US9173647B2 (en) | 2004-10-26 | 2015-11-03 | P Tech, Llc | Tissue fixation system |
US20060089646A1 (en) | 2004-10-26 | 2006-04-27 | Bonutti Peter M | Devices and methods for stabilizing tissue and implants |
US20060189993A1 (en) | 2004-11-09 | 2006-08-24 | Arthrotek, Inc. | Soft tissue conduit device |
US7909851B2 (en) | 2006-02-03 | 2011-03-22 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US7905904B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
US8088130B2 (en) | 2006-02-03 | 2012-01-03 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US7905903B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US7857830B2 (en) | 2006-02-03 | 2010-12-28 | Biomet Sports Medicine, Llc | Soft tissue repair and conduit device |
US7749250B2 (en) | 2006-02-03 | 2010-07-06 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
US9801708B2 (en) | 2004-11-05 | 2017-10-31 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8298262B2 (en) | 2006-02-03 | 2012-10-30 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US8118836B2 (en) | 2004-11-05 | 2012-02-21 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8137382B2 (en) | 2004-11-05 | 2012-03-20 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US8361113B2 (en) | 2006-02-03 | 2013-01-29 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8128658B2 (en) | 2004-11-05 | 2012-03-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to bone |
US8303604B2 (en) | 2004-11-05 | 2012-11-06 | Biomet Sports Medicine, Llc | Soft tissue repair device and method |
US9017381B2 (en) | 2007-04-10 | 2015-04-28 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US7658751B2 (en) | 2006-09-29 | 2010-02-09 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US8840645B2 (en) | 2004-11-05 | 2014-09-23 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US8998949B2 (en) | 2004-11-09 | 2015-04-07 | Biomet Sports Medicine, Llc | Soft tissue conduit device |
US7914539B2 (en) | 2004-11-09 | 2011-03-29 | Biomet Sports Medicine, Llc | Tissue fixation device |
US8034090B2 (en) | 2004-11-09 | 2011-10-11 | Biomet Sports Medicine, Llc | Tissue fixation device |
US7354627B2 (en) | 2004-12-22 | 2008-04-08 | Depuy Products, Inc. | Method for organizing the assembly of collagen fibers and compositions formed therefrom |
US7972354B2 (en) | 2005-01-25 | 2011-07-05 | Tyco Healthcare Group Lp | Method and apparatus for impeding migration of an implanted occlusive structure |
US9089323B2 (en) | 2005-02-22 | 2015-07-28 | P Tech, Llc | Device and method for securing body tissue |
US7618436B2 (en) | 2005-04-12 | 2009-11-17 | St. Jude Medical Puerto Rico Llc | Tissue puncture closure device with scroll gear transmission tamping system |
EP1871241B1 (en) | 2005-04-22 | 2012-12-19 | Rex Medical, L.P. | Closure device for left atrial appendage |
US7753935B2 (en) * | 2005-04-29 | 2010-07-13 | Vivasure Medical Limited | Interventional medical closure device |
US20060247776A1 (en) * | 2005-05-02 | 2006-11-02 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for augmenting intervertebral discs |
US20060276838A1 (en) * | 2005-06-07 | 2006-12-07 | Wensel Jeffrey P | Vascular puncture sealing method, apparatus, and system |
US20080015481A1 (en) * | 2005-05-04 | 2008-01-17 | Bergin Patrick J | Hemostatic bandage and method of use |
US8926654B2 (en) * | 2005-05-04 | 2015-01-06 | Cordis Corporation | Locator and closure device and method of use |
US8088144B2 (en) * | 2005-05-04 | 2012-01-03 | Ensure Medical, Inc. | Locator and closure device and method of use |
US7622628B2 (en) * | 2005-05-04 | 2009-11-24 | Innovasa Corporation | Hemostatic wire guided bandage and method of use |
US20060276836A1 (en) * | 2005-06-07 | 2006-12-07 | Bergin Patrick J | Hemostatic wire guided bandage and method of use |
US8795364B2 (en) | 2005-05-06 | 2014-08-05 | Kensey Nash Corporation | System and devices for the repair of a vertebral disc defect |
US7837705B2 (en) * | 2005-05-17 | 2010-11-23 | St. Jude Medical Puerto Rico Llc | Tissue puncture closure system with retractable sheath |
US7645286B2 (en) * | 2005-05-20 | 2010-01-12 | Neotract, Inc. | Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures |
US8945152B2 (en) | 2005-05-20 | 2015-02-03 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8157815B2 (en) | 2005-05-20 | 2012-04-17 | Neotract, Inc. | Integrated handle assembly for anchor delivery system |
US8529584B2 (en) | 2005-05-20 | 2013-09-10 | Neotract, Inc. | Median lobe band implant apparatus and method |
US8603106B2 (en) | 2005-05-20 | 2013-12-10 | Neotract, Inc. | Integrated handle assembly for anchor delivery system |
US9364212B2 (en) | 2005-05-20 | 2016-06-14 | Neotract, Inc. | Suture anchoring devices and methods for use |
US8834492B2 (en) * | 2005-05-20 | 2014-09-16 | Neotract, Inc. | Continuous indentation lateral lobe apparatus and method |
US9149266B2 (en) | 2005-05-20 | 2015-10-06 | Neotract, Inc. | Deforming anchor device |
US7909836B2 (en) | 2005-05-20 | 2011-03-22 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8333776B2 (en) | 2005-05-20 | 2012-12-18 | Neotract, Inc. | Anchor delivery system |
US7896891B2 (en) * | 2005-05-20 | 2011-03-01 | Neotract, Inc. | Apparatus and method for manipulating or retracting tissue and anatomical structure |
US8491606B2 (en) * | 2005-05-20 | 2013-07-23 | Neotract, Inc. | Median lobe retraction apparatus and method |
US8628542B2 (en) * | 2005-05-20 | 2014-01-14 | Neotract, Inc. | Median lobe destruction apparatus and method |
US7758594B2 (en) | 2005-05-20 | 2010-07-20 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US10925587B2 (en) | 2005-05-20 | 2021-02-23 | Neotract, Inc. | Anchor delivery system |
US9549739B2 (en) | 2005-05-20 | 2017-01-24 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US8668705B2 (en) * | 2005-05-20 | 2014-03-11 | Neotract, Inc. | Latching anchor device |
US9504461B2 (en) | 2005-05-20 | 2016-11-29 | Neotract, Inc. | Anchor delivery system |
US8425535B2 (en) | 2005-05-20 | 2013-04-23 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8394113B2 (en) | 2005-05-20 | 2013-03-12 | Neotract, Inc. | Coiled anchor device |
US10195014B2 (en) | 2005-05-20 | 2019-02-05 | Neotract, Inc. | Devices, systems and methods for treating benign prostatic hyperplasia and other conditions |
US20060293709A1 (en) | 2005-06-24 | 2006-12-28 | Bojarski Raymond A | Tissue repair device |
US8313497B2 (en) | 2005-07-01 | 2012-11-20 | Abbott Laboratories | Clip applier and methods of use |
US8951285B2 (en) * | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
US7824414B2 (en) * | 2005-07-22 | 2010-11-02 | Kensey Nash Corporation | System and devices for the repair of a vertebral disc defect |
US7595062B2 (en) | 2005-07-28 | 2009-09-29 | Depuy Products, Inc. | Joint resurfacing orthopaedic implant and associated method |
US7749247B2 (en) * | 2005-08-04 | 2010-07-06 | St. Jude Medical Puerto Rico, Llc | Tissue puncture closure device with coiled automatic tamping system |
US20070032824A1 (en) * | 2005-08-04 | 2007-02-08 | St. Jude Medical Puerto Rico B.V. | Tissue puncture closure device with track plug |
US7883517B2 (en) | 2005-08-08 | 2011-02-08 | Abbott Laboratories | Vascular suturing device |
US8267947B2 (en) | 2005-08-08 | 2012-09-18 | Abbott Laboratories | Vascular suturing device |
US8083754B2 (en) | 2005-08-08 | 2011-12-27 | Abbott Laboratories | Vascular suturing device with needle capture |
US8920442B2 (en) | 2005-08-24 | 2014-12-30 | Abbott Vascular Inc. | Vascular opening edge eversion methods and apparatuses |
US9456811B2 (en) | 2005-08-24 | 2016-10-04 | Abbott Vascular Inc. | Vascular closure methods and apparatuses |
US20070060895A1 (en) | 2005-08-24 | 2007-03-15 | Sibbitt Wilmer L Jr | Vascular closure methods and apparatuses |
DE602006020488D1 (en) * | 2005-10-05 | 2011-04-14 | Univ Loma Linda Med | Vascular wound closure device |
JP2009511190A (en) * | 2005-10-13 | 2009-03-19 | エンドルミナル セラピューティクス, インコーポレイテッド | Intramural treatment with channels |
US7691127B2 (en) * | 2005-12-13 | 2010-04-06 | Cardiva Medical, Inc. | Drug eluting vascular closure devices and methods |
US9179897B2 (en) * | 2005-12-13 | 2015-11-10 | Cardiva Medical, Inc. | Vascular closure devices and methods providing hemostatic enhancement |
US8267942B2 (en) * | 2005-12-23 | 2012-09-18 | Ethicon, Inc. | Systems and methods for closing a vessel wound |
US20070156174A1 (en) * | 2006-01-03 | 2007-07-05 | Arthrotek, Inc. | Method and apparatus for repairing a meniscus |
US8382794B2 (en) | 2006-01-04 | 2013-02-26 | St. Jude Medical Puerto Rico Llc | Balloon insertion apparatus and method of sealing a tissue puncture |
WO2007090150A2 (en) * | 2006-01-31 | 2007-08-09 | Cook Biotech Incorporated | Fistula grafts and related methods and systems for treating fistulae |
US7959650B2 (en) | 2006-09-29 | 2011-06-14 | Biomet Sports Medicine, Llc | Adjustable knotless loops |
US11259792B2 (en) | 2006-02-03 | 2022-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for coupling anatomical features |
US10517587B2 (en) | 2006-02-03 | 2019-12-31 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8801783B2 (en) | 2006-09-29 | 2014-08-12 | Biomet Sports Medicine, Llc | Prosthetic ligament system for knee joint |
US11311287B2 (en) | 2006-02-03 | 2022-04-26 | Biomet Sports Medicine, Llc | Method for tissue fixation |
US8771352B2 (en) | 2011-05-17 | 2014-07-08 | Biomet Sports Medicine, Llc | Method and apparatus for tibial fixation of an ACL graft |
US8251998B2 (en) | 2006-08-16 | 2012-08-28 | Biomet Sports Medicine, Llc | Chondral defect repair |
US9078644B2 (en) | 2006-09-29 | 2015-07-14 | Biomet Sports Medicine, Llc | Fracture fixation device |
US9271713B2 (en) | 2006-02-03 | 2016-03-01 | Biomet Sports Medicine, Llc | Method and apparatus for tensioning a suture |
US9149267B2 (en) | 2006-02-03 | 2015-10-06 | Biomet Sports Medicine, Llc | Method and apparatus for coupling soft tissue to a bone |
US9538998B2 (en) | 2006-02-03 | 2017-01-10 | Biomet Sports Medicine, Llc | Method and apparatus for fracture fixation |
US8562647B2 (en) * | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for securing soft tissue to bone |
US8506597B2 (en) | 2011-10-25 | 2013-08-13 | Biomet Sports Medicine, Llc | Method and apparatus for interosseous membrane reconstruction |
US8574235B2 (en) | 2006-02-03 | 2013-11-05 | Biomet Sports Medicine, Llc | Method for trochanteric reattachment |
US8936621B2 (en) | 2006-02-03 | 2015-01-20 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8562645B2 (en) | 2006-09-29 | 2013-10-22 | Biomet Sports Medicine, Llc | Method and apparatus for forming a self-locking adjustable loop |
US8597327B2 (en) | 2006-02-03 | 2013-12-03 | Biomet Manufacturing, Llc | Method and apparatus for sternal closure |
US8652172B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Flexible anchors for tissue fixation |
US8968364B2 (en) | 2006-02-03 | 2015-03-03 | Biomet Sports Medicine, Llc | Method and apparatus for fixation of an ACL graft |
US8652171B2 (en) | 2006-02-03 | 2014-02-18 | Biomet Sports Medicine, Llc | Method and apparatus for soft tissue fixation |
US8496657B2 (en) | 2006-02-07 | 2013-07-30 | P Tech, Llc. | Methods for utilizing vibratory energy to weld, stake and/or remove implants |
US7967820B2 (en) | 2006-02-07 | 2011-06-28 | P Tech, Llc. | Methods and devices for trauma welding |
US11253296B2 (en) | 2006-02-07 | 2022-02-22 | P Tech, Llc | Methods and devices for intracorporeal bonding of implants with thermal energy |
US11278331B2 (en) | 2006-02-07 | 2022-03-22 | P Tech Llc | Method and devices for intracorporeal bonding of implants with thermal energy |
WO2007124201A2 (en) * | 2006-02-23 | 2007-11-01 | Saratech, Inc. | System s and methods for repairing an annulus |
US20090281498A1 (en) * | 2006-04-19 | 2009-11-12 | Acosta Pablo G | Devices, system and methods for minimally invasive abdominal surgical procedures |
US7976554B2 (en) | 2006-04-19 | 2011-07-12 | Vibrynt, Inc. | Devices, tools and methods for performing minimally invasive abdominal surgical procedures |
US8342183B2 (en) | 2006-04-19 | 2013-01-01 | Vibrynt, Inc. | Devices and methods for treatment of obesity |
US8187297B2 (en) | 2006-04-19 | 2012-05-29 | Vibsynt, Inc. | Devices and methods for treatment of obesity |
US8070768B2 (en) | 2006-04-19 | 2011-12-06 | Vibrynt, Inc. | Devices and methods for treatment of obesity |
US8556925B2 (en) | 2007-10-11 | 2013-10-15 | Vibrynt, Inc. | Devices and methods for treatment of obesity |
US8398668B2 (en) | 2006-04-19 | 2013-03-19 | Vibrynt, Inc. | Devices and methods for treatment of obesity |
US8585733B2 (en) | 2006-04-19 | 2013-11-19 | Vibrynt, Inc | Devices, tools and methods for performing minimally invasive abdominal surgical procedures |
US9017361B2 (en) | 2006-04-20 | 2015-04-28 | Covidien Lp | Occlusive implant and methods for hollow anatomical structure |
US11246638B2 (en) | 2006-05-03 | 2022-02-15 | P Tech, Llc | Methods and devices for utilizing bondable materials |
US20070270907A1 (en) * | 2006-05-19 | 2007-11-22 | Stokes Michael J | Suture locking device |
US7850710B2 (en) * | 2006-05-23 | 2010-12-14 | St. Jude Medical Puerto Rico Llc | Puncture closure apparatuses, sealing plugs, and related methods |
WO2010062971A1 (en) | 2008-11-26 | 2010-06-03 | Anova Corporation | Methods and apparatus for anulus repair |
US8764835B2 (en) | 2006-06-13 | 2014-07-01 | Bret A. Ferree | Intervertebral disc treatment methods and apparatus |
US9232938B2 (en) | 2006-06-13 | 2016-01-12 | Anova Corp. | Method and apparatus for closing fissures in the annulus fibrosus |
US8834496B2 (en) | 2006-06-13 | 2014-09-16 | Bret A. Ferree | Soft tissue repair methods and apparatus |
US8556930B2 (en) | 2006-06-28 | 2013-10-15 | Abbott Laboratories | Vessel closure device |
US7736376B2 (en) * | 2006-07-05 | 2010-06-15 | Olympus Medical Systems Corp. | Living body wall fixing tool used in endoscope |
US20080058865A1 (en) * | 2006-08-21 | 2008-03-06 | Wilk Peter J | Surgical closure device and associated method |
US7749248B2 (en) * | 2006-09-18 | 2010-07-06 | St. Jude Medical Puerto Rico Llc | Flexible tamping device |
US8672969B2 (en) | 2006-09-29 | 2014-03-18 | Biomet Sports Medicine, Llc | Fracture fixation device |
US8500818B2 (en) | 2006-09-29 | 2013-08-06 | Biomet Manufacturing, Llc | Knee prosthesis assembly with ligament link |
US9918826B2 (en) | 2006-09-29 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US11259794B2 (en) | 2006-09-29 | 2022-03-01 | Biomet Sports Medicine, Llc | Method for implanting soft tissue |
US8029532B2 (en) * | 2006-10-11 | 2011-10-04 | Cook Medical Technologies Llc | Closure device with biomaterial patches |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
EP2066272A2 (en) | 2006-12-28 | 2009-06-10 | Vibrynt, Inc. | Devices and methods for treatment of obesity |
US8617185B2 (en) | 2007-02-13 | 2013-12-31 | P Tech, Llc. | Fixation device |
US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
US8911461B2 (en) * | 2007-03-13 | 2014-12-16 | Mitralign, Inc. | Suture cutter and method of cutting suture |
US8845723B2 (en) * | 2007-03-13 | 2014-09-30 | Mitralign, Inc. | Systems and methods for introducing elements into tissue |
US8556988B2 (en) * | 2007-03-15 | 2013-10-15 | Insightra Medical, Inc. | Apparatus and repair of defect in inguinal canal and other muscular structures |
US20090192530A1 (en) | 2008-01-29 | 2009-07-30 | Insightra Medical, Inc. | Fortified mesh for tissue repair |
EP2574287B1 (en) | 2007-03-30 | 2015-04-22 | Sentreheart, Inc. | Devices for closing the left atrial appendage |
US7951159B2 (en) * | 2007-04-04 | 2011-05-31 | Ethicon Endo-Surgery, Inc. | Method for plicating and fastening gastric tissue |
US7815653B2 (en) * | 2007-04-04 | 2010-10-19 | Ethicon Endo-Surgery, Inc. | Method for plicating and fastening gastric tissue |
US7799040B2 (en) * | 2007-04-04 | 2010-09-21 | Ethicon Endo-Surgery, Inc. | Device for plicating and fastening gastric tissue |
US7803165B2 (en) * | 2007-04-04 | 2010-09-28 | Ethicon Endo-Surgery, Inc. | Device for plicating and fastening gastric tissue |
WO2008152617A2 (en) | 2007-06-15 | 2008-12-18 | Zerusa Limited | A closure device |
US8574244B2 (en) | 2007-06-25 | 2013-11-05 | Abbott Laboratories | System for closing a puncture in a vessel wall |
US8758366B2 (en) | 2007-07-09 | 2014-06-24 | Neotract, Inc. | Multi-actuating trigger anchor delivery system |
US8906059B2 (en) | 2007-07-13 | 2014-12-09 | Rex Medical, L.P. | Vascular hole closure device |
US20090024106A1 (en) * | 2007-07-17 | 2009-01-22 | Morris Edward J | Method and apparatus for maintaining access |
US8568445B2 (en) | 2007-08-21 | 2013-10-29 | St. Jude Medical Puerto Rico Llc | Extra-vascular sealing device and method |
US8333787B2 (en) | 2007-12-31 | 2012-12-18 | St. Jude Medical Puerto Rico Llc | Vascular closure device having a flowable sealing material |
US7771455B2 (en) * | 2007-08-31 | 2010-08-10 | Ken Christopher G M | Closure medical device |
US20090062742A1 (en) * | 2007-08-31 | 2009-03-05 | John Anthony Rotella | Blunted Safety Needle |
US7867253B2 (en) * | 2007-08-31 | 2011-01-11 | Kimberly-Clark Worldwide, Inc. | Suture retention hub |
US8157816B2 (en) | 2007-08-31 | 2012-04-17 | Kimberly-Clark Worldwide, Inc. | Gastropexy kit |
US9456816B2 (en) | 2007-09-12 | 2016-10-04 | Transluminal Technologies, Llc | Closure device, deployment apparatus, and method of deploying a closure device |
US8876861B2 (en) * | 2007-09-12 | 2014-11-04 | Transluminal Technologies, Inc. | Closure device, deployment apparatus, and method of deploying a closure device |
JP5426553B2 (en) * | 2007-09-12 | 2014-02-26 | トランスルミナル テクノロジーズ リミテッド ライアビリティー カンパニー | Closure device, placement device, and method of placing a closure device |
US8858591B2 (en) * | 2007-10-31 | 2014-10-14 | Radi Medical Systems Ab | Method and device for sealing a puncture hole in a bodily organ |
KR101450943B1 (en) * | 2007-12-21 | 2014-10-21 | 쿄세라 메디칼 가부시키가이샤 | Device for cell transplantation |
US8840640B2 (en) | 2007-12-31 | 2014-09-23 | St. Jude Medical Puerto Rico Llc | Vascular closure device having an improved plug |
US9282953B2 (en) | 2007-12-31 | 2016-03-15 | St. Jude Medical Puerto Rico Llc | Systems and methods for locating and closing a tissue puncture |
US20110029013A1 (en) | 2008-02-15 | 2011-02-03 | Mcguckin James F | Vascular Hole Closure Device |
US8920462B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US8920463B2 (en) | 2008-02-15 | 2014-12-30 | Rex Medical, L.P. | Vascular hole closure device |
US9226738B2 (en) | 2008-02-15 | 2016-01-05 | Rex Medical, L.P. | Vascular hole closure delivery device |
US8491629B2 (en) | 2008-02-15 | 2013-07-23 | Rex Medical | Vascular hole closure delivery device |
US8070772B2 (en) | 2008-02-15 | 2011-12-06 | Rex Medical, L.P. | Vascular hole closure device |
US20090216267A1 (en) * | 2008-02-26 | 2009-08-27 | Boston Scientific Scimed, Inc. | Closure device with rapidly dissolving anchor |
US9445804B2 (en) * | 2008-04-01 | 2016-09-20 | The Lonnie And Shannon Paulos Trust (As Amended And Restated) | Suture anchoring assemblies and methods of use |
US9282965B2 (en) | 2008-05-16 | 2016-03-15 | Abbott Laboratories | Apparatus and methods for engaging tissue |
US8118832B1 (en) | 2008-06-16 | 2012-02-21 | Morris Innovative, Inc. | Method and apparatus for sealing access |
EP2344048B1 (en) * | 2008-07-30 | 2016-09-07 | Neotract, Inc. | Slotted anchor device |
CN102112064B (en) * | 2008-07-30 | 2014-06-18 | 新域公司 | Anchor delivery system with replaceable cartridge |
US8088093B2 (en) * | 2008-08-07 | 2012-01-03 | Ottuso Patrick | Wound penetrating hemostatic device impregnated with coagulant, antibiotic and/or anesthetic |
US9943302B2 (en) | 2008-08-12 | 2018-04-17 | Covidien Lp | Medical device for wound closure and method of use |
US9271706B2 (en) * | 2008-08-12 | 2016-03-01 | Covidien Lp | Medical device for wound closure and method of use |
EP2330985A4 (en) | 2008-09-04 | 2015-11-18 | Curaseal Inc | Inflatable devices for enteric fistula treatment |
US8945211B2 (en) * | 2008-09-12 | 2015-02-03 | Mitralign, Inc. | Tissue plication device and method for its use |
EP2344049B1 (en) | 2008-10-03 | 2021-01-27 | C.R.Bard, Inc. | Implantable prosthesis |
US8163022B2 (en) | 2008-10-14 | 2012-04-24 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US9486191B2 (en) | 2009-01-09 | 2016-11-08 | Abbott Vascular, Inc. | Closure devices |
US9414820B2 (en) | 2009-01-09 | 2016-08-16 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US20100179589A1 (en) | 2009-01-09 | 2010-07-15 | Abbott Vascular Inc. | Rapidly eroding anchor |
US20100185234A1 (en) * | 2009-01-16 | 2010-07-22 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US8375553B2 (en) * | 2009-02-20 | 2013-02-19 | Boston Scientific Scimed, Inc. | Locking element for vascular closure device |
US9913634B2 (en) | 2009-02-20 | 2018-03-13 | Boston Scientific Scimed, Inc. | Locking element for vascular closure device |
US8529598B2 (en) * | 2009-02-20 | 2013-09-10 | Boston Scientific Scimed, Inc. | Tissue puncture closure device |
US8052914B2 (en) | 2009-02-20 | 2011-11-08 | Boston Scientific Scimed, Inc. | Modified plug for arteriotomy closure |
US8292918B2 (en) * | 2009-02-20 | 2012-10-23 | Boston Scientific Scimed, Inc. | Composite plug for arteriotomy closure and method of use |
US8317824B2 (en) * | 2009-02-20 | 2012-11-27 | Boston Scientific Scimed, Inc. | Tissue puncture closure device |
EP2400899A4 (en) | 2009-02-24 | 2015-03-18 | P Tech Llc | Methods and devices for utilizing bondable materials |
AU2015200980B2 (en) * | 2009-04-01 | 2017-02-02 | Atricure, Inc. | Tissue ligation devices and controls therefor |
US9198664B2 (en) | 2009-04-01 | 2015-12-01 | Sentreheart, Inc. | Tissue ligation devices and controls therefor |
US8343227B2 (en) | 2009-05-28 | 2013-01-01 | Biomet Manufacturing Corp. | Knee prosthesis assembly with ligament link |
US8192456B2 (en) * | 2009-07-13 | 2012-06-05 | Vascular Solutions, Inc. | Metal vascular aperture closure device |
WO2011019374A1 (en) * | 2009-08-14 | 2011-02-17 | St. Jude Medical Puerto Rico Llc | Carrier tube for vascular closure device and methods |
US9232954B2 (en) | 2009-08-20 | 2016-01-12 | Howmedica Osteonics Corp. | Flexible ACL instrumentation, kit and method |
US20110054492A1 (en) | 2009-08-26 | 2011-03-03 | Abbott Laboratories | Medical device for repairing a fistula |
US8858592B2 (en) | 2009-11-24 | 2014-10-14 | Covidien Lp | Wound plugs |
US11357486B2 (en) * | 2009-12-30 | 2022-06-14 | Vivasure Medical Limited | Closure system and uses thereof |
US8460319B2 (en) | 2010-01-11 | 2013-06-11 | Anulex Technologies, Inc. | Intervertebral disc annulus repair system and method |
US8444673B2 (en) * | 2010-02-11 | 2013-05-21 | Boston Scientific Scimed, Inc. | Automatic vascular closure deployment devices and methods |
EP2558014A4 (en) | 2010-04-13 | 2017-11-29 | Sentreheart, Inc. | Methods and devices for treating atrial fibrillation |
WO2011137224A1 (en) * | 2010-04-29 | 2011-11-03 | Danny Azriel Sherwinter | Systems and methods for facilitating closure of bodily openings |
US10568628B2 (en) | 2017-05-23 | 2020-02-25 | Muffin Incorporated | Closing device for tissue openings |
US8932325B2 (en) | 2010-05-19 | 2015-01-13 | Cook Medical Technologies Llc | Devices and methods useful for sealing bodily openings |
US8685059B2 (en) | 2010-06-08 | 2014-04-01 | Essential Medical Llc | Self-locking closure device for percutaneously sealing punctures |
US8663252B2 (en) | 2010-09-01 | 2014-03-04 | Abbott Cardiovascular Systems, Inc. | Suturing devices and methods |
US9370353B2 (en) | 2010-09-01 | 2016-06-21 | Abbott Cardiovascular Systems, Inc. | Suturing devices and methods |
US8597340B2 (en) | 2010-09-17 | 2013-12-03 | Boston Scientific Scimed, Inc. | Torque mechanism actuated bioabsorbable vascular closure device |
US9737289B2 (en) * | 2010-10-29 | 2017-08-22 | Vectec S.A. | Single use, disposable, tissue suspender device |
JP5981930B2 (en) | 2010-11-09 | 2016-08-31 | トランスルミナル テクノロジーズ リミテッド ライアビリティー カンパニー | Specially designed magnesium-aluminum alloy and its use in medicine in hemodynamic environment |
US8758402B2 (en) | 2010-12-17 | 2014-06-24 | Boston Scientific Scimed, Inc. | Tissue puncture closure device |
US9060751B2 (en) | 2010-12-30 | 2015-06-23 | Vivasure Medical Limited | Surgical closure systems and methods |
US9713463B2 (en) | 2011-01-13 | 2017-07-25 | Howmedica Osteonics Corp | Toggle bolt assembly and method of assembly |
EP2672898A1 (en) | 2011-02-09 | 2013-12-18 | C.R. Bard Inc. | T-fastener suture delivery system |
WO2012140506A2 (en) * | 2011-04-11 | 2012-10-18 | David Keane | Method and prosthesis for percutaneous hernia repair |
US9161749B2 (en) | 2011-04-14 | 2015-10-20 | Neotract, Inc. | Method and apparatus for treating sexual dysfunction |
CN106974692B (en) | 2011-06-08 | 2021-06-01 | 森特里心脏股份有限公司 | Tissue ligation device and tensioning device therefor |
CN103874466B (en) | 2011-06-16 | 2016-10-05 | 库拉希尔公司 | Device and correlation technique for fistula treatment |
US9131941B2 (en) | 2011-06-17 | 2015-09-15 | Curaseal Inc. | Fistula treatment devices and methods |
AU2012202202B2 (en) | 2011-07-20 | 2017-05-11 | Rex Medical, L.P. | Vascular hole closure delivery device |
WO2013023075A1 (en) | 2011-08-09 | 2013-02-14 | Cook General Biotechnology Llc | Vial useable in tissue extraction procedures |
US10485524B2 (en) | 2011-10-25 | 2019-11-26 | Essential Medical, Inc. | Instrument and methods for surgically closing percutaneous punctures |
US9357991B2 (en) | 2011-11-03 | 2016-06-07 | Biomet Sports Medicine, Llc | Method and apparatus for stitching tendons |
US9370350B2 (en) | 2011-11-10 | 2016-06-21 | Biomet Sports Medicine, Llc | Apparatus for coupling soft tissue to a bone |
US9357992B2 (en) | 2011-11-10 | 2016-06-07 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
US9381013B2 (en) | 2011-11-10 | 2016-07-05 | Biomet Sports Medicine, Llc | Method for coupling soft tissue to a bone |
EP2747668B1 (en) * | 2011-11-16 | 2017-01-04 | St. Jude Medical Puerto Rico LLC | Large bore vascular closure device with inner seal |
US9445803B2 (en) * | 2011-11-23 | 2016-09-20 | Howmedica Osteonics Corp. | Filamentary suture anchor |
US9492156B2 (en) * | 2011-11-28 | 2016-11-15 | St. Jude Medical Puerto Rico Llc | Large bore anchor device |
US9332976B2 (en) | 2011-11-30 | 2016-05-10 | Abbott Cardiovascular Systems, Inc. | Tissue closure device |
US8968336B2 (en) | 2011-12-07 | 2015-03-03 | Edwards Lifesciences Corporation | Self-cinching surgical clips and delivery system |
US9017347B2 (en) | 2011-12-22 | 2015-04-28 | Edwards Lifesciences Corporation | Suture clip deployment devices |
US9259217B2 (en) | 2012-01-03 | 2016-02-16 | Biomet Manufacturing, Llc | Suture Button |
US8382775B1 (en) | 2012-01-08 | 2013-02-26 | Vibrynt, Inc. | Methods, instruments and devices for extragastric reduction of stomach volume |
US9314362B2 (en) | 2012-01-08 | 2016-04-19 | Vibrynt, Inc. | Methods, instruments and devices for extragastric reduction of stomach volume |
US9737286B2 (en) | 2012-02-29 | 2017-08-22 | Vivasure Medical Limited | Implants and methods for percutaneous perforation closure |
US10292801B2 (en) | 2012-03-29 | 2019-05-21 | Neotract, Inc. | System for delivering anchors for treating incontinence |
US8864778B2 (en) | 2012-04-10 | 2014-10-21 | Abbott Cardiovascular Systems, Inc. | Apparatus and method for suturing body lumens |
US8858573B2 (en) | 2012-04-10 | 2014-10-14 | Abbott Cardiovascular Systems, Inc. | Apparatus and method for suturing body lumens |
US9241707B2 (en) | 2012-05-31 | 2016-01-26 | Abbott Cardiovascular Systems, Inc. | Systems, methods, and devices for closing holes in body lumens |
US10130353B2 (en) | 2012-06-29 | 2018-11-20 | Neotract, Inc. | Flexible system for delivering an anchor |
US9498202B2 (en) | 2012-07-10 | 2016-11-22 | Edwards Lifesciences Corporation | Suture securement devices |
US10016193B2 (en) | 2013-11-18 | 2018-07-10 | Edwards Lifesciences Ag | Multiple-firing crimp device and methods for using and manufacturing same |
US9757104B2 (en) | 2012-07-19 | 2017-09-12 | Essential Medical, Inc. | Multi-lumen tamper tube |
US8821494B2 (en) | 2012-08-03 | 2014-09-02 | Howmedica Osteonics Corp. | Surgical instruments and methods of use |
US10070850B2 (en) | 2012-10-19 | 2018-09-11 | Cook Medical Technologies Llc | Vascular closure with multiple connections |
US9943298B2 (en) | 2012-10-19 | 2018-04-17 | Cook Medical Technologies Llc | Vascular closure with shape memory characteristic |
US20140172012A1 (en) | 2012-12-13 | 2014-06-19 | Cook Medical Technologies Llc | Vascular closure device suture tension mechanism |
US9364209B2 (en) | 2012-12-21 | 2016-06-14 | Abbott Cardiovascular Systems, Inc. | Articulating suturing device |
US9592047B2 (en) | 2012-12-21 | 2017-03-14 | Edwards Lifesciences Corporation | System for securing sutures |
US10076377B2 (en) | 2013-01-05 | 2018-09-18 | P Tech, Llc | Fixation systems and methods |
AU2014209124A1 (en) | 2013-01-28 | 2015-09-17 | Cartiva, Inc. | Systems and methods for orthopedic repair |
US9737294B2 (en) | 2013-01-28 | 2017-08-22 | Cartiva, Inc. | Method and system for orthopedic repair |
US9131932B2 (en) * | 2013-02-01 | 2015-09-15 | St. Jude Medical Puerto Rico Llc | Dual lumen carrier tube with retractable sleeve and methods |
US9955958B2 (en) * | 2013-02-06 | 2018-05-01 | St. Jude Medical Puerto Rico Llc | Extra-vascular closure device with releasable sealing plug |
US9265600B2 (en) * | 2013-02-27 | 2016-02-23 | Orthopediatrics Corp. | Graft fixation |
US9402620B2 (en) | 2013-03-04 | 2016-08-02 | Howmedica Osteonics Corp. | Knotless filamentary fixation devices, assemblies and systems and methods of assembly and use |
US9757119B2 (en) | 2013-03-08 | 2017-09-12 | Biomet Sports Medicine, Llc | Visual aid for identifying suture limbs arthroscopically |
US9788826B2 (en) | 2013-03-11 | 2017-10-17 | Howmedica Osteonics Corp. | Filamentary fixation device and assembly and method of assembly, manufacture and use |
CA2902064C (en) | 2013-03-12 | 2021-06-01 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
US9463013B2 (en) * | 2013-03-13 | 2016-10-11 | Stryker Corporation | Adjustable continuous filament structure and method of manufacture and use |
US9918827B2 (en) | 2013-03-14 | 2018-03-20 | Biomet Sports Medicine, Llc | Scaffold for spring ligament repair |
US10758216B2 (en) | 2013-03-14 | 2020-09-01 | Cook Medical Technologies Llc | Internal closure systems and devices |
US9850013B2 (en) | 2013-03-15 | 2017-12-26 | Vivasure Medical Limited | Loading devices and methods for percutaneous perforation closure systems |
US9724082B2 (en) | 2013-03-15 | 2017-08-08 | Cook Medical Technologies Llc | Delivery system for tissue opening closures |
WO2014150154A1 (en) | 2013-03-15 | 2014-09-25 | Essential Medical, Inc. | Vascular closure devices and methods of use |
RU2532877C1 (en) * | 2013-04-15 | 2014-11-10 | Константин Викторович Пучков | Method for temporary fixation of abdominal and pelvic organs in laparoscopic surgeries |
US10292694B2 (en) | 2013-04-22 | 2019-05-21 | Pivot Medical, Inc. | Method and apparatus for attaching tissue to bone |
GB2513336A (en) * | 2013-04-23 | 2014-10-29 | 52 Vbl Ltd | Device and method for reducing blood flow from a bullet wound |
US10154835B2 (en) | 2013-05-09 | 2018-12-18 | Essential Medical, Inc. | Vascular closure device with conforming plug member |
CA2902233C (en) | 2013-07-11 | 2021-01-12 | Edwards Lifesciences Corporation | Knotless suture fastener installation system |
US10070857B2 (en) | 2013-08-31 | 2018-09-11 | Mitralign, Inc. | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
WO2015066549A1 (en) | 2013-10-31 | 2015-05-07 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
US10610211B2 (en) | 2013-12-12 | 2020-04-07 | Howmedica Osteonics Corp. | Filament engagement system and methods of use |
US10136886B2 (en) | 2013-12-20 | 2018-11-27 | Biomet Sports Medicine, Llc | Knotless soft tissue devices and techniques |
EP3858254A1 (en) | 2013-12-23 | 2021-08-04 | Arrow International LLC | Vascular closure device |
EP3151756B1 (en) | 2014-05-30 | 2019-08-28 | Edwards Lifesciences Corporation | Systems for securing sutures |
US9615822B2 (en) | 2014-05-30 | 2017-04-11 | Biomet Sports Medicine, Llc | Insertion tools and method for soft anchor |
US9700291B2 (en) | 2014-06-03 | 2017-07-11 | Biomet Sports Medicine, Llc | Capsule retractor |
US10098628B2 (en) | 2014-07-22 | 2018-10-16 | Cook Medical Technologies Llc | Anchor deployment system, device, and method of treatment |
US10039543B2 (en) | 2014-08-22 | 2018-08-07 | Biomet Sports Medicine, Llc | Non-sliding soft anchor |
US9795366B2 (en) | 2014-09-18 | 2017-10-24 | Edwards Lifesciences Corporation | Bio-absorbable wound closure device and method |
US9986992B2 (en) | 2014-10-28 | 2018-06-05 | Stryker Corporation | Suture anchor and associated methods of use |
EP3229703A4 (en) | 2014-12-10 | 2018-09-05 | Edwards Lifesciences AG | Multiple-firing securing device and methods for using and manufacturing same |
WO2016096932A1 (en) | 2014-12-15 | 2016-06-23 | Vivasure Medical Limited | Closure apparatus with flexible sealable member and flexible support member |
EP3232939B1 (en) | 2014-12-15 | 2020-09-23 | Vivasure Medical Limited | Implantable sealable member with mesh layer |
US10568616B2 (en) | 2014-12-17 | 2020-02-25 | Howmedica Osteonics Corp. | Instruments and methods of soft tissue fixation |
CN107106162B (en) | 2014-12-24 | 2020-10-27 | 爱德华兹生命科学公司 | Suture clip deployment device |
US9955980B2 (en) | 2015-02-24 | 2018-05-01 | Biomet Sports Medicine, Llc | Anatomic soft tissue repair |
US10470759B2 (en) | 2015-03-16 | 2019-11-12 | Edwards Lifesciences Corporation | Suture securement devices |
US10130369B2 (en) | 2015-03-24 | 2018-11-20 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
EP4282371A3 (en) | 2015-03-24 | 2024-03-06 | AtriCure, Inc. | Devices for left atrial appendage closure |
US9974534B2 (en) | 2015-03-31 | 2018-05-22 | Biomet Sports Medicine, Llc | Suture anchor with soft anchor of electrospun fibers |
US10555727B2 (en) | 2015-06-26 | 2020-02-11 | Essential Medical, Inc. | Vascular closure device with removable guide member |
US10058393B2 (en) | 2015-10-21 | 2018-08-28 | P Tech, Llc | Systems and methods for navigation and visualization |
WO2017102941A1 (en) | 2015-12-15 | 2017-06-22 | Vivasure Medical Limited | Arteriotomy closure apparatus with slotted shoe for advantageous pressure distribution |
EP3419531B1 (en) | 2016-02-26 | 2024-04-03 | AtriCure, Inc. | Devices for left atrial appendage closure |
US10939905B2 (en) | 2016-08-26 | 2021-03-09 | Edwards Lifesciences Corporation | Suture clips, deployment devices therefor, and methods of use |
WO2018057963A1 (en) | 2016-09-23 | 2018-03-29 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
US10575841B1 (en) | 2016-11-29 | 2020-03-03 | The Lonnie and Shannon Paulos Trust | Soft locking suture anchor assembly and methods of use |
US10863980B2 (en) | 2016-12-28 | 2020-12-15 | Edwards Lifesciences Corporation | Suture fastener having spaced-apart layers |
US10426449B2 (en) | 2017-02-16 | 2019-10-01 | Abbott Cardiovascular Systems, Inc. | Articulating suturing device with improved actuation and alignment mechanisms |
US11369474B2 (en) * | 2017-07-17 | 2022-06-28 | Warsaw Orthopedic, Inc. | Bone implant having a mesh |
WO2019126718A1 (en) | 2017-12-23 | 2019-06-27 | Neotract, Inc. | Expandable tissue engagement apparatus and method |
US10772621B2 (en) | 2018-02-02 | 2020-09-15 | Abbott Cardiovascular Systems, Inc. | Suture management devices, methods, and systems |
USD902405S1 (en) | 2018-02-22 | 2020-11-17 | Stryker Corporation | Self-punching bone anchor inserter |
WO2019191316A1 (en) | 2018-03-27 | 2019-10-03 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
US11504105B2 (en) | 2019-01-25 | 2022-11-22 | Rex Medical L.P. | Vascular hole closure device |
US20220031358A1 (en) | 2020-08-03 | 2022-02-03 | Neotract, Inc. | Handle and cartridge system for medical interventions |
US11844511B2 (en) | 2021-07-08 | 2023-12-19 | Arthrex, Inc. | Surgical system and method permitting percutaneous insertion of anchors |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989011301A1 (en) * | 1988-05-16 | 1989-11-30 | Kensey Nash Corporation | Device for sealing percutaneous puncture in a vessel |
US4946468A (en) * | 1989-06-06 | 1990-08-07 | Mitek Surgical Products, Inc. | Suture anchor and suture anchor installation tool |
US5021059A (en) * | 1990-05-07 | 1991-06-04 | Kensey Nash Corporation | Plug device with pulley for sealing punctures in tissue and methods of use |
US5092884A (en) * | 1988-03-24 | 1992-03-03 | American Cyanamid Company | Surgical composite structure having absorbable and nonabsorbable components |
US5116357A (en) * | 1990-10-11 | 1992-05-26 | Eberbach Mark A | Hernia plug and introducer apparatus |
WO1993008746A2 (en) * | 1991-11-08 | 1993-05-13 | Kensey Nash Corp | Hemostatic puncture closure system and method of use |
WO1994013211A1 (en) * | 1992-12-10 | 1994-06-23 | Perclose, Inc. | Vascular puncture site suturing device and method |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5220928A (en) * | 1983-08-22 | 1993-06-22 | Stryker Sales Corporation | Surgical procedure for joining tissue in an internal body cavity |
US5274074A (en) * | 1987-12-17 | 1993-12-28 | United States Surgical Corporation | Medical devices fabricated from homopolymers and copolymers having recurring carbonate units |
US5053096A (en) * | 1990-01-26 | 1991-10-01 | Eastman Kodak Company | Apparatus and method for splicing webs of indeterminate length |
US5141515A (en) * | 1990-10-11 | 1992-08-25 | Eberbach Mark A | Apparatus and methods for repairing hernias |
US5254133A (en) * | 1991-04-24 | 1993-10-19 | Seid Arnold S | Surgical implantation device and related method of use |
AT400339B (en) * | 1991-09-10 | 1995-12-27 | Plasser Bahnbaumasch Franz | MACHINE ARRANGEMENT FOR RENEWING A TRACK |
US5290217A (en) * | 1991-10-10 | 1994-03-01 | Earl K. Sipes | Method and apparatus for hernia repair |
US5222974A (en) * | 1991-11-08 | 1993-06-29 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
US5342393A (en) * | 1992-08-27 | 1994-08-30 | Duke University | Method and device for vascular repair |
US5312794A (en) * | 1992-12-29 | 1994-05-17 | Shell Oil Company | Catalyst system for olefin polymerization |
US5312435A (en) * | 1993-05-17 | 1994-05-17 | Kensey Nash Corporation | Fail predictable, reinforced anchor for hemostatic puncture closure |
-
1994
- 1994-10-21 US US08/327,262 patent/US5545178A/en not_active Expired - Lifetime
-
1995
- 1995-04-27 EP EP95918857A patent/EP0759725A1/en not_active Withdrawn
- 1995-04-27 CA CA002188751A patent/CA2188751A1/en not_active Abandoned
- 1995-04-27 AU AU24620/95A patent/AU2462095A/en not_active Abandoned
- 1995-04-27 WO PCT/US1995/005187 patent/WO1995029635A1/en not_active Application Discontinuation
- 1995-04-27 JP JP7528367A patent/JPH09512461A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5092884A (en) * | 1988-03-24 | 1992-03-03 | American Cyanamid Company | Surgical composite structure having absorbable and nonabsorbable components |
WO1989011301A1 (en) * | 1988-05-16 | 1989-11-30 | Kensey Nash Corporation | Device for sealing percutaneous puncture in a vessel |
US4946468A (en) * | 1989-06-06 | 1990-08-07 | Mitek Surgical Products, Inc. | Suture anchor and suture anchor installation tool |
US5021059A (en) * | 1990-05-07 | 1991-06-04 | Kensey Nash Corporation | Plug device with pulley for sealing punctures in tissue and methods of use |
US5116357A (en) * | 1990-10-11 | 1992-05-26 | Eberbach Mark A | Hernia plug and introducer apparatus |
WO1993008746A2 (en) * | 1991-11-08 | 1993-05-13 | Kensey Nash Corp | Hemostatic puncture closure system and method of use |
WO1994013211A1 (en) * | 1992-12-10 | 1994-06-23 | Perclose, Inc. | Vascular puncture site suturing device and method |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998040016A3 (en) * | 1997-03-12 | 1998-10-29 | Advanced Closure Systems Inc | Universal introducer |
WO1998040017A3 (en) * | 1997-03-12 | 1998-10-22 | Advanced Closure Systems Inc | Vascular sealing device |
US7081125B2 (en) | 1997-03-12 | 2006-07-25 | Neomend, Inc. | Universal introducer |
US8221452B2 (en) | 1997-03-12 | 2012-07-17 | Neomend, Inc. | Systems and methods for sealing a vascular puncture |
US8057494B2 (en) | 1999-06-22 | 2011-11-15 | Ethicon Endo-Surgery, Inc. | Methods and devices for tissue reconfiguration |
US7857823B2 (en) | 1999-06-22 | 2010-12-28 | Ethicon Endo-Surgery, Inc. | Tissue reconfiguration |
DE10027186A1 (en) * | 2000-05-31 | 2001-12-20 | Aesculap Ag & Co Kg | Device for closing an opening in a fabric layer |
DE10027186C2 (en) * | 2000-05-31 | 2002-06-27 | Aesculap Ag & Co Kg | Device for closing an opening in a fabric layer |
US8888812B2 (en) | 2000-12-14 | 2014-11-18 | Cordis Corporation | Plug with collet and apparatus and methods for delivering such plugs |
DE10310995B3 (en) * | 2003-03-06 | 2004-09-16 | Aesculap Ag & Co. Kg | Closure device for a puncture channel and applicator device |
US7311720B2 (en) | 2003-03-06 | 2007-12-25 | Aesculap Ag & Co. Kg | Closure device for a puncture channel and applicator device |
EP3025653B1 (en) * | 2006-06-21 | 2021-06-16 | Cook Biotech Incorporated | Fistula grafts useful for treating gastrointestinal fistulae |
US8241323B2 (en) | 2006-09-07 | 2012-08-14 | Terumo Kabushiki Kaisha | Tissue closing device |
US7828854B2 (en) | 2006-10-31 | 2010-11-09 | Ethicon, Inc. | Implantable repair device |
US9636207B2 (en) | 2006-10-31 | 2017-05-02 | Ethicon, Inc. | Implantable repair device |
US8388633B2 (en) | 2006-10-31 | 2013-03-05 | Ethicon, Inc. | Implantable repair device |
US8591534B2 (en) | 2006-10-31 | 2013-11-26 | Ethicon, Inc. | Implantable repair device |
US8852216B2 (en) | 2007-03-23 | 2014-10-07 | Ethicon Endo-Surgery, Inc. | Tissue approximation methods |
US8500759B2 (en) | 2007-09-26 | 2013-08-06 | Ethicon, Inc. | Hernia mesh support device |
US9295538B2 (en) | 2007-09-26 | 2016-03-29 | Ethicon, Inc. | Methods of repairing a hernia using a hernia support device |
EP3556297A1 (en) * | 2010-05-19 | 2019-10-23 | Cook Medical Technologies, LLC | Devices for sealing bodily openings |
US10098620B2 (en) | 2010-07-12 | 2018-10-16 | Terumo Puerto Rico, L.L.C. | Compactionless tissue puncture closure device and methods |
KR101550511B1 (en) * | 2010-08-03 | 2015-09-07 | 더블유.엘. 고어 앤드 어소시에이트스, 인코포레이티드 | Tissue plug |
AU2011286371B2 (en) * | 2010-08-03 | 2015-04-23 | W. L. Gore & Associates, Inc. | Tissue plug |
CN103068319A (en) * | 2010-08-03 | 2013-04-24 | 戈尔企业控股股份有限公司 | Tissue plug |
WO2012018454A1 (en) | 2010-08-03 | 2012-02-09 | Gore Enterprise Holdings, Inc. | Tissue plug |
US11064985B2 (en) | 2010-08-03 | 2021-07-20 | W. L. Gore & Associates, Inc. | Tissue plug |
WO2012158931A1 (en) * | 2011-05-19 | 2012-11-22 | St. Jude Medical Puerto Rico Llc | Procedural sheath adapter for vascular closure device |
US10111648B2 (en) | 2011-05-19 | 2018-10-30 | Terumo Puerto Rico, Llc | Procedural sheath adapter for vascular closure device |
WO2014028166A1 (en) * | 2012-08-15 | 2014-02-20 | St. Jude Medical Puerto Rico Llc | Vascular closure device anchor |
US9307966B2 (en) | 2012-08-15 | 2016-04-12 | St. Jude Medical Puerto Rico Llc | Vascular closure device anchor |
FR3091988A1 (en) * | 2019-01-29 | 2020-07-31 | Advance | INSTRUMENTATION ALLOWING THE PLACEMENT, IN A BONE OR OTHER BODY TISSUE, OF AN ANCHOR CONNECTED TO AT LEAST ONE SUTURE WIRE |
Also Published As
Publication number | Publication date |
---|---|
US5545178A (en) | 1996-08-13 |
EP0759725A1 (en) | 1997-03-05 |
CA2188751A1 (en) | 1995-11-09 |
JPH09512461A (en) | 1997-12-16 |
AU2462095A (en) | 1995-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5545178A (en) | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating | |
US5531759A (en) | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating | |
US9782155B2 (en) | Vascular hole closure device | |
US5700277A (en) | Hemostatic vessel puncture closure with filament lock | |
US7942888B2 (en) | Vascular hole closure device | |
US11123059B2 (en) | Vascular hole closure delivery device | |
US5312435A (en) | Fail predictable, reinforced anchor for hemostatic puncture closure | |
CA2426474C (en) | Absorbable fastener and applying apparatus | |
US6267772B1 (en) | Implantable prosthesis | |
US20210330307A1 (en) | Vascular hole closure device | |
AU2002232798A1 (en) | Absorbable fastener and applying apparatus | |
US9943300B2 (en) | Vascular hole closure device | |
US20180049731A1 (en) | Closing device for tissue openings | |
WO2016100866A1 (en) | Port closure device and methods of use | |
EP3160362B1 (en) | Expandable mesh with locking feature | |
US8906059B2 (en) | Vascular hole closure device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AM AU BB BG BR BY CA CN CZ EE FI GE HU JP KE KG KP KR KZ LK LR LT LV MD MG MN MW MX NO NZ PL RO RU SD SG SI SK TJ TT UA UG UZ VN |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): KE SZ AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2188751 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1995918857 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1995918857 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1995918857 Country of ref document: EP |