WO1996018731A3 - Isolation of nucleic acid - Google Patents
Isolation of nucleic acid Download PDFInfo
- Publication number
- WO1996018731A3 WO1996018731A3 PCT/GB1995/002893 GB9502893W WO9618731A3 WO 1996018731 A3 WO1996018731 A3 WO 1996018731A3 GB 9502893 W GB9502893 W GB 9502893W WO 9618731 A3 WO9618731 A3 WO 9618731A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- sample
- isolation
- support
- bound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51846396A JP3787354B2 (en) | 1994-12-12 | 1995-12-12 | Nucleic acid isolation method |
AT95940351T ATE272110T1 (en) | 1994-12-12 | 1995-12-12 | ISOLATION OF NUCLEIC ACIDS |
CA002207608A CA2207608C (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
AU41829/96A AU706211B2 (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
US08/849,686 US20040215011A1 (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
EP95940351A EP0796327B1 (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
DE69533317T DE69533317T2 (en) | 1994-12-12 | 1995-12-12 | ISOLATION OF NUCLEIC ACIDS |
US11/234,001 US7173124B2 (en) | 1994-12-12 | 2005-09-23 | Isolation of nucleic acid |
US11/671,426 US20070190559A1 (en) | 1994-12-12 | 2007-02-05 | Isolation of nucleic acid |
US12/054,332 US7989614B2 (en) | 1994-12-12 | 2008-03-24 | Isolation of nucleic acid |
US12/130,959 US20090149646A1 (en) | 1994-12-12 | 2008-05-30 | Isolation of Nucleic Acid |
US12/130,926 US20090068724A1 (en) | 1994-12-12 | 2008-05-30 | Isolation of Nucleic Acid |
US13/160,428 US8691969B2 (en) | 1994-12-12 | 2011-06-14 | Isolation of nucleic acid |
US14/183,999 US20140291576A1 (en) | 1994-12-12 | 2014-02-19 | Isolation of nucleic acid |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9425138.6A GB9425138D0 (en) | 1994-12-12 | 1994-12-12 | Isolation of nucleic acid |
GB9425138.6 | 1994-12-12 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08849686 A-371-Of-International | 1995-12-12 | ||
US08/849,686 A-371-Of-International US20040215011A1 (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
US11/234,001 Continuation US7173124B2 (en) | 1994-12-12 | 2005-09-23 | Isolation of nucleic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996018731A2 WO1996018731A2 (en) | 1996-06-20 |
WO1996018731A3 true WO1996018731A3 (en) | 1996-09-12 |
Family
ID=10765877
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1995/002893 WO1996018731A2 (en) | 1994-12-12 | 1995-12-12 | Isolation of nucleic acid |
Country Status (9)
Country | Link |
---|---|
US (8) | US20040215011A1 (en) |
EP (1) | EP0796327B1 (en) |
JP (1) | JP3787354B2 (en) |
AT (1) | ATE272110T1 (en) |
AU (1) | AU706211B2 (en) |
CA (1) | CA2207608C (en) |
DE (1) | DE69533317T2 (en) |
GB (1) | GB9425138D0 (en) |
WO (1) | WO1996018731A2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8026068B2 (en) | 2002-01-08 | 2011-09-27 | Roche Molecular Systems, Inc. | Use of silica material in an amplification reaction |
US8101744B2 (en) | 2007-04-20 | 2012-01-24 | Roche Diagnostics Operations, Inc. | Isolation and purification of nucleic acids with a solid phase |
US8691969B2 (en) | 1994-12-12 | 2014-04-08 | Life Technologies As | Isolation of nucleic acid |
US11845081B2 (en) | 2007-07-13 | 2023-12-19 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
Families Citing this family (162)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2965131B2 (en) | 1995-07-07 | 1999-10-18 | 東洋紡績株式会社 | Magnetic carrier for nucleic acid binding and nucleic acid isolation method using the same |
US5990302A (en) * | 1996-07-12 | 1999-11-23 | Toyo Boseki Kabushiki Kaisha | Method for isolating ribonucleic acid |
US6143496A (en) | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
GB9709728D0 (en) * | 1997-05-13 | 1997-07-02 | Dynal As | Single step method |
AU9317198A (en) | 1997-09-17 | 1999-04-05 | Gentra Systems, Inc. | Apparatuses and methods for isolating nucleic acid |
EP1950312A1 (en) | 1998-02-02 | 2008-07-30 | QIAGEN North American Holdings, Inc. | Processes for isolating, amplifying and characterizing DNA |
AU2654899A (en) * | 1998-02-02 | 1999-08-16 | Gentra Systems, Inc. | Processes for isolating, amplifying and characterizing dna |
JP5300112B2 (en) * | 1998-02-02 | 2013-09-25 | キアジエン・ノース・アメリカン・ホールデイングス・インコーポレーテツド | Compositions and methods for using a lysis matrix for isolating DNA |
US6534262B1 (en) | 1998-05-14 | 2003-03-18 | Whitehead Institute For Biomedical Research | Solid phase technique for selectively isolating nucleic acids |
AU764494B2 (en) * | 1998-09-10 | 2003-08-21 | Whatman Plc | Product and method for separation of a sample containing multiple sources of genetic material using a solid medium |
US5973138A (en) * | 1998-10-30 | 1999-10-26 | Becton Dickinson And Company | Method for purification and manipulation of nucleic acids using paramagnetic particles |
FI990082A0 (en) * | 1999-01-18 | 1999-01-18 | Labsystems Oy | Purification process using magnetic particles |
US7790865B1 (en) | 1999-02-02 | 2010-09-07 | Qiagen North American Holdings, Inc | Eluting reagents, methods and kits for isolating DNA |
DE69938976D1 (en) * | 1999-03-11 | 2008-08-07 | Whatman Inc | Solid medium and methods for storage and rapid purification of nucleic acids |
EP1171584A1 (en) * | 1999-04-21 | 2002-01-16 | Annovis, Inc. | Magnetic dna extraction kit for plants |
ES2258429T3 (en) * | 1999-07-15 | 2006-09-01 | Qiagen Gmbh | METHODS TO SEPARATE SUBSTRATES IN PARTICLES OF A SOLUTION, AT THE TIME THAT THE LOSS OF PARTICLES IS MINIMIZED. |
US6936414B2 (en) * | 1999-12-22 | 2005-08-30 | Abbott Laboratories | Nucleic acid isolation method and kit |
GB0001450D0 (en) | 2000-01-21 | 2000-03-08 | Genpoint As | Cell isolation method |
GB0013658D0 (en) * | 2000-06-05 | 2000-07-26 | Dynal Asa | Nucleic acid isolation |
US20050239125A1 (en) * | 2000-09-06 | 2005-10-27 | Hodge Timothy A | Methods for genotype screening |
EP1978110B1 (en) * | 2000-09-06 | 2010-05-26 | Transnetyx, Inc. | Computer-based method and system for screening genomic DNA |
JP2004508057A (en) * | 2000-09-06 | 2004-03-18 | ホッジ ティモシー エイ | System, method and apparatus for screening for transgenic and target specific mutations |
EP1349951A4 (en) * | 2001-01-09 | 2005-08-24 | Whitehead Biomedical Inst | Methods and reagents for the isolation of nucleic acids |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
JPWO2003006650A1 (en) * | 2001-07-09 | 2004-11-04 | 旭化成株式会社 | Nucleic acid purification method and detection method using nonwoven fabric |
US7148343B2 (en) | 2001-10-12 | 2006-12-12 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify RNA |
US20050032105A1 (en) | 2001-10-12 | 2005-02-10 | Bair Robert Jackson | Compositions and methods for using a solid support to purify DNA |
US7893228B2 (en) | 2001-10-12 | 2011-02-22 | Qiagen North American Holdings, Inc. | Compositions and methods for using a solid support to purify RNA |
KR100445560B1 (en) * | 2001-10-31 | 2004-08-21 | (주)바이오넥스 | Method of manufacturing kit for isolating nucleic acids or biological materials, kit manufactured by the method, and apparatus using the kit |
AU2002359522A1 (en) * | 2001-11-28 | 2003-06-10 | Applera Corporation | Compositions and methods of selective nucleic acid isolation |
US8110351B2 (en) | 2002-01-16 | 2012-02-07 | Invitrogen Dynal As | Method for isolating nucleic acids and protein from a single sample |
US7786295B2 (en) | 2002-02-15 | 2010-08-31 | Qiegen North American Holdings, Inc | Method to isolate DNA |
GB0212826D0 (en) | 2002-05-31 | 2002-07-10 | Dna Res Innovations Ltd | Materials and methods relating to polyions and substance delivery |
GB0215185D0 (en) | 2002-07-01 | 2002-08-07 | Genovision As | Binding a target substance |
US20040029166A1 (en) * | 2002-07-29 | 2004-02-12 | Jsr Corporation | Nucleic acid-separating method and nucleic acid-extracting reagent |
JP5441290B2 (en) † | 2002-10-04 | 2014-03-12 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | Methods and materials using chemicals as tools for storing nucleic acids on nucleic acid purification system media |
US20040180445A1 (en) * | 2003-03-12 | 2004-09-16 | Domanico Michael J. | Methods and compositions for purification of nucleic acid from a host cell |
WO2004108925A1 (en) * | 2003-06-04 | 2004-12-16 | Qiagen As | Method for sequentially isolating dna and rna from the same nucleic acid-containing sample |
EP1654361B2 (en) † | 2003-07-25 | 2023-01-18 | Life Technologies Corporation | Methods and compositions for preparing rna from a fixed sample |
WO2005011867A2 (en) | 2003-07-31 | 2005-02-10 | Handylab, Inc. | Processing particle-containing samples |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
ES2553097T3 (en) * | 2004-05-03 | 2015-12-04 | Handylab, Inc. | Processing of samples containing polynucleotides |
US7459548B2 (en) | 2004-05-21 | 2008-12-02 | Mo Bio Laboratories, Inc. | Kits and processes for removing contaminants from nucleic acids in environmental and biological samples |
US20060024712A1 (en) * | 2004-06-25 | 2006-02-02 | Invitrogen Corporation | Separation of nucleic acid |
EP1776458A2 (en) | 2004-07-30 | 2007-04-25 | Agencourt Bioscience Corporation | Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers |
WO2006052680A1 (en) | 2004-11-05 | 2006-05-18 | Qiagen North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
US20060166223A1 (en) * | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
US20090215124A1 (en) | 2005-02-15 | 2009-08-27 | Weidong Cao | Nucleic acid isolation methods and materials and devices thereof |
CA2599576C (en) * | 2005-03-10 | 2015-09-15 | Gen-Probe Incorporated | Systems and methods to perform assays for detecting or quantifying analytes within samples |
CN104810126B (en) * | 2005-06-23 | 2018-08-10 | 西门子医疗系统诊断股份有限公司 | Magnetic particle and production and preparation method thereof with closed ultrathin silica layer |
DE102005047736B4 (en) * | 2005-09-29 | 2008-08-14 | Aj Innuscreen Gmbh | Method and system for isolating nucleic acids from any complex starting materials |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
WO2007112114A2 (en) | 2006-03-24 | 2007-10-04 | Handylab, Inc. | Integrated system for processing microfluidic samples, and method of using same |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US20100216657A1 (en) * | 2006-05-16 | 2010-08-26 | Arcxis Biotechnologies, Inc. | Pcr-free sample preparation and detection systems for high speed biologic analysis and identification |
EP2041318A2 (en) * | 2006-06-26 | 2009-04-01 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
US20080003575A1 (en) * | 2006-06-28 | 2008-01-03 | Sigma-Aldrich Co. | Methods and composition for RNA extraction |
US10131935B2 (en) | 2006-07-11 | 2018-11-20 | Aj Innuscreen Gmbh | Method for parallel isolation of viral nucleic acids |
DE102006032610C5 (en) * | 2006-07-11 | 2016-09-15 | Aj Innuscreen Gmbh | Method for the parallel isolation of viral nucleic acids |
CN103497991A (en) | 2006-11-06 | 2014-01-08 | 科隆迪亚戈有限公司 | Device and method for analysis using binding members |
EP2091647A2 (en) | 2006-11-14 | 2009-08-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
EP2132311A1 (en) * | 2007-03-21 | 2009-12-16 | Ibis Biosciences, Inc. | Reagents for nucleic acid purification |
ES2665280T3 (en) | 2007-06-29 | 2018-04-25 | Becton, Dickinson And Company | Methods for the extraction and purification of components of biological samples |
US8324372B2 (en) | 2007-07-13 | 2012-12-04 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
CA3006347A1 (en) | 2007-07-23 | 2009-01-29 | Clondiag Gmbh | Methods and devices for determining values indicative of the presence and/or amount of nucleic acids |
EP2191012A1 (en) * | 2007-09-21 | 2010-06-02 | Streck, Inc. | Nucleic acid isolation in preserved whole blood |
GB0719022D0 (en) * | 2007-09-28 | 2007-11-07 | Mole Genetics As | Isolation method |
US8478544B2 (en) | 2007-11-21 | 2013-07-02 | Cosmosid Inc. | Direct identification and measurement of relative populations of microorganisms with direct DNA sequencing and probabilistic methods |
DK2229587T3 (en) | 2007-11-21 | 2016-09-05 | Cosmosid Inc | Genome identification system |
WO2009117167A1 (en) * | 2008-01-02 | 2009-09-24 | Blood Cell Storage, Inc. | Devices and processes for nucleic acid extraction |
CN104531673B (en) | 2008-02-15 | 2018-03-16 | 生命科技公司 | Method and kit for DNA extractions |
DE102008010693A1 (en) | 2008-02-22 | 2009-08-27 | Qiagen Gmbh | New matrix materials, processes for their preparation and their use in methods of isolating biomolecules |
DE102008010692A1 (en) | 2008-02-22 | 2009-08-27 | Qiagen Gmbh | New matrices, processes for their preparation and their use in methods of isolating biomolecules |
CL2009000647A1 (en) * | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Pharmaceutical composition for treating or preventing liver cancer comprising a combination of a chemotherapeutic agent and an anti-glypican 3 antibody; agent for attenuating a side effect comprising said antibody; method of treating or preventing liver cancer of a subject. |
DE102008029356A1 (en) * | 2008-06-20 | 2009-12-24 | Siemens Healthcare Diagnostics Gmbh | Process for the purification of nucleic acids, in particular from fixed tissue |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
CN102264899A (en) * | 2008-11-04 | 2011-11-30 | 血细胞保存公司 | Nucleic acid extraction on curved glass surfaces |
US20110275126A1 (en) * | 2009-01-16 | 2011-11-10 | Arkray, Inc. | Method for Producing Nucleic Acid Sample and Method for Producing Nucleic Acid Amplification Product Using the Same |
US8790916B2 (en) | 2009-05-14 | 2014-07-29 | Genestream, Inc. | Microfluidic method and system for isolating particles from biological fluid |
WO2011026030A1 (en) * | 2009-08-31 | 2011-03-03 | Mbio Diagnostics Corporation | Integrated sample preparation and analyte detection |
US20110223588A1 (en) * | 2010-03-09 | 2011-09-15 | Biosample Llc | Solid Phase Nucleic Acid Extraction From Small Sample Volumes, and Release of Controlled Quantities |
PT2588609T (en) | 2010-06-29 | 2018-04-02 | Exscale Biospecimen Solutions Ab | Method and kit for sequential isolation of nucleotide species from a sample |
US8747084B2 (en) | 2010-07-21 | 2014-06-10 | Aperia Technologies, Inc. | Peristaltic pump |
US11203786B2 (en) | 2010-08-06 | 2021-12-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
US11031095B2 (en) | 2010-08-06 | 2021-06-08 | Ariosa Diagnostics, Inc. | Assay systems for determination of fetal copy number variation |
US10533223B2 (en) | 2010-08-06 | 2020-01-14 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
US20140342940A1 (en) | 2011-01-25 | 2014-11-20 | Ariosa Diagnostics, Inc. | Detection of Target Nucleic Acids using Hybridization |
US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
US20130040375A1 (en) | 2011-08-08 | 2013-02-14 | Tandem Diagnotics, Inc. | Assay systems for genetic analysis |
US8700338B2 (en) | 2011-01-25 | 2014-04-15 | Ariosa Diagnosis, Inc. | Risk calculation for evaluation of fetal aneuploidy |
US20130261003A1 (en) | 2010-08-06 | 2013-10-03 | Ariosa Diagnostics, In. | Ligation-based detection of genetic variants |
US10167508B2 (en) | 2010-08-06 | 2019-01-01 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities |
GB201020095D0 (en) | 2010-11-26 | 2011-01-12 | Invitrogen Dynal As | Nucleic acid preparation method |
JP2014503222A (en) * | 2011-01-18 | 2014-02-13 | エバリスト ジェノミックス, インコーポレイテッド | Prognostic signs of colorectal cancer recurrence |
US11270781B2 (en) | 2011-01-25 | 2022-03-08 | Ariosa Diagnostics, Inc. | Statistical analysis for non-invasive sex chromosome aneuploidy determination |
US9994897B2 (en) | 2013-03-08 | 2018-06-12 | Ariosa Diagnostics, Inc. | Non-invasive fetal sex determination |
US8756020B2 (en) | 2011-01-25 | 2014-06-17 | Ariosa Diagnostics, Inc. | Enhanced risk probabilities using biomolecule estimations |
US10131947B2 (en) | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
WO2012142516A1 (en) | 2011-04-15 | 2012-10-18 | Becton, Dickinson And Company | Scanning real-time microfluidic thermo-cycler and methods for synchronized thermocycling and scanning optical detection |
WO2012159063A2 (en) | 2011-05-19 | 2012-11-22 | Blood Cell Strorage, Inc. | Gravity flow fluidic device for nucleic acid extraction |
EP2546199A1 (en) | 2011-07-14 | 2013-01-16 | Université Catholique De Louvain | Solid iron oxide support for isolation of microorganisms |
JP5924888B2 (en) * | 2011-08-26 | 2016-05-25 | 関東化學株式会社 | Nucleic acid extraction method, nucleic acid extraction reagent kit, and nucleic acid extraction reagent |
US8712697B2 (en) | 2011-09-07 | 2014-04-29 | Ariosa Diagnostics, Inc. | Determination of copy number variations using binomial probability calculations |
ES2825905T3 (en) | 2011-09-30 | 2021-05-17 | Becton Dickinson Co | Unified test strip |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
WO2013067509A1 (en) * | 2011-11-04 | 2013-05-10 | Bio-Rad Laboratories, Inc. | Simultaneous purification of cell components |
WO2013067202A1 (en) | 2011-11-04 | 2013-05-10 | Handylab, Inc. | Polynucleotide sample preparation device |
WO2013091102A1 (en) * | 2011-12-21 | 2013-06-27 | Geneohm Sciences Canada Inc. | Enrichment & isolation of microbial cells & microbial nucleic acids from a biological sample |
CN107881219B (en) | 2012-02-03 | 2021-09-10 | 贝克顿·迪金森公司 | External file for molecular diagnostic test assignment and compatibility determination between tests |
EP2812339B1 (en) | 2012-02-09 | 2019-11-06 | Life Technologies Corporation | Hydrophobic diacrylamide compound |
CN104302783B (en) | 2012-02-09 | 2018-02-09 | 生命技术公司 | Conjugated polymer beads and preparation method thereof |
JP6170074B2 (en) | 2012-02-09 | 2017-07-26 | ライフ テクノロジーズ コーポレーション | Hydrophilic polymer particles and method for producing the same |
US9658195B2 (en) | 2012-02-15 | 2017-05-23 | Bio-Rad Laboratories, Inc. | Electronic control of pH and ionic strength |
US20150299766A1 (en) | 2012-02-23 | 2015-10-22 | Dow Agrosciences Llc | Automation of barrier-based plant nucleic acid and protein extraction |
CN104254452B (en) | 2012-03-20 | 2017-07-07 | 阿佩利亚科技公司 | Tire filling system |
US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
US10289800B2 (en) | 2012-05-21 | 2019-05-14 | Ariosa Diagnostics, Inc. | Processes for calculating phased fetal genomic sequences |
WO2014018195A1 (en) | 2012-06-21 | 2014-01-30 | Monsanto Technology Llc | Lysis buffer and methods for extraction of dna from plant material |
EP2875156A4 (en) | 2012-07-19 | 2016-02-24 | Ariosa Diagnostics Inc | Multiplexed sequential ligation-based detection of genetic variants |
CN103571824B (en) | 2012-08-09 | 2016-04-13 | 财团法人工业技术研究院 | Compositions and methods for isolating nucleic acids |
US20150252356A1 (en) | 2012-08-28 | 2015-09-10 | Bio Cube System Co., Ltd. | Porous solid phase for rapidly isolating biological molecules for nucleic acid amplification reaction from biological sample, and use thereof |
GB201216387D0 (en) | 2012-09-13 | 2012-10-31 | Ge Healthcare Uk Ltd | Solid matrix for one step nucleic acid amplification |
US11453258B2 (en) | 2013-03-12 | 2022-09-27 | Aperia Technologies, Inc. | System for tire inflation |
US10245908B2 (en) | 2016-09-06 | 2019-04-02 | Aperia Technologies, Inc. | System for tire inflation |
US10144254B2 (en) | 2013-03-12 | 2018-12-04 | Aperia Technologies, Inc. | Tire inflation system |
US9604157B2 (en) | 2013-03-12 | 2017-03-28 | Aperia Technologies, Inc. | Pump with water management |
US10052428B2 (en) | 2013-03-15 | 2018-08-21 | Fenwal, Inc. | Methods and systems for the filterless reduction of leukocytes in a biological fluid |
WO2015053293A1 (en) * | 2013-10-07 | 2015-04-16 | 三井化学株式会社 | Pcr primer set for bacterial dna amplification, kit for detecting and/or identifying bacterial species, and method for detecting and/or identifying bacterial species |
WO2015120447A1 (en) | 2014-02-10 | 2015-08-13 | Zymo Research Corporation | Methods of nucleic acid capture |
US20150252407A1 (en) * | 2014-03-09 | 2015-09-10 | Nvigen, Inc. | Nanostructure and methods of nucleic acid isolation |
WO2015168342A1 (en) | 2014-04-29 | 2015-11-05 | Accudx Corporation | A novel affinity matrix and devices for isolation and purification of rna and dna for point of care molecular devices |
US9879223B2 (en) | 2014-07-30 | 2018-01-30 | Fenwal, Inc. | Methods and systems for the reduction of leukocytes in a biological fluid |
JP6437250B2 (en) | 2014-09-03 | 2018-12-12 | 株式会社ミズホメディー | Pretreatment method and nucleic acid extraction kit used therefor |
US10000750B2 (en) | 2014-10-09 | 2018-06-19 | Promega Corporation | Method of isolating nucleic acid |
US10364428B2 (en) | 2014-11-14 | 2019-07-30 | Corning Incorporated | Methods and kits for post-IVT RNA purification |
CN107208136A (en) * | 2014-12-18 | 2017-09-26 | 通用电气医疗集团英国有限公司 | Pass through the analysis analyte detection on the solid support for the nucleic acid amplification being coupled with immunoassay |
GB201504459D0 (en) * | 2015-03-17 | 2015-04-29 | Moorlodge Biotech Ventures Ltd | Isolation of DNA |
US9422596B1 (en) | 2015-04-27 | 2016-08-23 | Norgen Biotek Corp. | Methods and columns for nucleic acid purification |
CN107922974B (en) | 2015-07-02 | 2021-11-09 | 生命技术公司 | Coupling of carboxyl-functional hydrophilic microbeads |
WO2017004556A1 (en) | 2015-07-02 | 2017-01-05 | Life Technologies Corporation | Polymer substrates formed from carboxy functional acrylamide |
WO2017007774A1 (en) | 2015-07-06 | 2017-01-12 | Life Technologies Corporation | Substrates and methods useful in sequencing |
EP3344643A4 (en) | 2015-09-04 | 2019-05-01 | Qiagen Sciences LLC | Methods for co-isolation of nucelic acids and proteins |
CN108026570A (en) * | 2015-09-11 | 2018-05-11 | 康宁股份有限公司 | The composition and method of purification of nucleic acid from blood sample |
US20180135040A1 (en) | 2016-02-16 | 2018-05-17 | Life Magnetics, Inc. | Methods for separating nucleic acids with graphene coated magnetic beads |
US20190135774A1 (en) * | 2016-04-21 | 2019-05-09 | Cell Data Sciences, Inc. | Biomolecule processing from fixed biological samples |
WO2017192902A1 (en) * | 2016-05-04 | 2017-11-09 | Children's Hospital & Research Center At Oakland | Rapid extraction of nucleic acids from clinical samples for downstream applications |
DE102016121483B4 (en) | 2016-11-09 | 2020-06-18 | Axagarius Gmbh & Co. Kg | Particulate solid composite material for nucleic acid purification, containing magnetic nanoparticles, process for its production and its use |
US11129673B2 (en) | 2017-05-05 | 2021-09-28 | Uptake Medical Technology Inc. | Extra-airway vapor ablation for treating airway constriction in patients with asthma and COPD |
CN111356770B (en) | 2017-09-18 | 2023-12-08 | 相达生物科技国际有限公司 | Method for separating, purifying and/or concentrating short-chain nucleic acid fragments using aqueous two-phase system |
US11642920B2 (en) | 2018-11-27 | 2023-05-09 | Aperia Technologies, Inc. | Hub-integrated inflation system |
TWI733302B (en) * | 2020-01-09 | 2021-07-11 | 創想生物科技有限公司 | A method of isolating nucleic acids and the system thereof |
KR20220075978A (en) | 2020-11-30 | 2022-06-08 | (주)바이오니아 | Method of Separating Nucleic Acid by Using Binding Buffer with Chemicals Having Low-Mid Dielectric Constant |
CN112626174A (en) * | 2020-12-16 | 2021-04-09 | 广州源井生物科技有限公司 | Cell lysis solution and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993025912A2 (en) * | 1992-06-09 | 1993-12-23 | Medical Research Council | Automated preparation of nucleic acids |
Family Cites Families (228)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US873102A (en) | 1907-06-21 | 1907-12-10 | William W Sly | Clutch. |
SE328534B (en) * | 1965-08-27 | 1970-09-21 | Astra Ab | |
US4055469A (en) | 1976-12-10 | 1977-10-25 | Eastman Kodak Company | Purification of microbial enzyme extracts using synthetic polyelectrolytes |
JPS598164B2 (en) | 1977-11-30 | 1984-02-23 | 三菱重工業株式会社 | Tanning equipment for filter materials such as dust masks |
AU530410B2 (en) * | 1978-02-21 | 1983-07-14 | Sintef | Preparing aqueous emulsions |
JPS5940227B2 (en) * | 1980-06-24 | 1984-09-28 | 富士通株式会社 | Reactive sputtering method |
DE3132491A1 (en) * | 1980-08-22 | 1982-07-01 | Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad | METHOD FOR PERFORMING ANALYTICAL DETERMINATIONS BY MEANS OF THE CHEMILUMINESCENCE METHOD AND APPLICATION OF THE METHOD FOR IMMUNASSAYS |
US4379843A (en) * | 1981-01-26 | 1983-04-12 | Peter Cashion | Immobilization of polynucleotides and polypeptides with tritylated polysaccharides |
US5055556A (en) | 1981-10-06 | 1991-10-08 | The Board Of Trustees Of The Leland Stanford Jr. Univ. | Fluorescent conjugates for analysis of molecules and cells |
IL65131A0 (en) * | 1982-02-28 | 1982-04-30 | Yeda Res & Dev | Process for the production of agarose-polyaldehyde beads and their biological applications |
NO155316C (en) | 1982-04-23 | 1987-03-11 | Sintef | PROCEDURE FOR MAKING MAGNETIC POLYMER PARTICLES. |
US4695537A (en) * | 1982-05-21 | 1987-09-22 | The University Of Tennessee Research Corp. | Particles sensitized with detergent-treated antigen for agglutination immunoassay |
GR79124B (en) | 1982-12-22 | 1984-10-02 | Genentech Inc | |
US4861705A (en) | 1983-01-31 | 1989-08-29 | Yeda Research And Development Company, Ltd. | Method for removing components of biological fluids |
DE3310337A1 (en) | 1983-03-22 | 1984-09-27 | Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg | METHOD FOR CARRYING OUT HYBRIDIZATION REACTIONS |
US4672040A (en) * | 1983-05-12 | 1987-06-09 | Advanced Magnetics, Inc. | Magnetic particles for use in separations |
US4648975A (en) * | 1983-08-17 | 1987-03-10 | Pedro B. Macedo | Process of using improved silica-based chromatographic supports containing additives |
US4920061A (en) * | 1984-03-02 | 1990-04-24 | The University Of Texas System | Biological magnetic colloids |
US4652517A (en) | 1984-06-11 | 1987-03-24 | Diagnostic Research Limited Partnership | Methods for the in vitro detection and identification of unknown pathogens or genetic entities |
AU571979B2 (en) | 1984-07-06 | 1988-04-28 | Ciba-Geigy Ag | Ionically modified polysaccharides |
GB8501671D0 (en) * | 1985-01-23 | 1985-02-27 | Allen G J | Immunoassay |
GB8507706D0 (en) | 1985-03-25 | 1985-05-01 | Genetics Int Inc | Magnetic nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4897444A (en) * | 1985-05-31 | 1990-01-30 | The Research Foundation Of The State University Of New York | Immobilized fluorogenic substrates for enzymes; and processes for their preparation |
US4710472A (en) | 1985-09-25 | 1987-12-01 | The United States Of America As Represented By The Secretary Of The Navy | Magnetic separation device |
US4889916A (en) | 1985-11-19 | 1989-12-26 | The Johns Hopkins University | Protein label and drug delivery system |
US5076950A (en) * | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
US4772550A (en) | 1986-02-10 | 1988-09-20 | Miles Inc. | Heterogeneous specific binding assay employing an aggregatable binding reagent |
US4871433A (en) | 1986-04-04 | 1989-10-03 | Materials Research Corporation | Method and apparatus for improving the uniformity ion bombardment in a magnetron sputtering system |
US6881536B1 (en) * | 1986-04-30 | 2005-04-19 | Bioveris Corporation | Particle based electrochemiluminescent assays |
FR2600655B1 (en) | 1986-06-30 | 1988-10-21 | Centre Nat Rech Scient | PROTEIN FRACTION EXTRACTED FROM GROWTH FACTOR ACTIVITIES, OBTAINING AND APPLICATION AS A STIMULATION AND POTENTIALIZING AGENT FOR GROWTH FACTOR ACTIVITIES |
US4843012A (en) * | 1986-09-17 | 1989-06-27 | Genetics Institute, Inc. | Novel composition for nucleic acid purification |
DE3639949A1 (en) | 1986-11-22 | 1988-06-09 | Diagen Inst Molekularbio | METHOD FOR SEPARATING LONG CHAIN NUCLEIC ACIDS |
US4935342A (en) * | 1986-12-01 | 1990-06-19 | Syngene, Inc. | Method of isolating and purifying nucleic acids from biological samples |
US4767670A (en) | 1987-01-21 | 1988-08-30 | E. I. Du Pont De Nemours And Company | Chromatographic supports for separation of oligonucleotides |
US4874813A (en) | 1987-02-09 | 1989-10-17 | Shannessy Daniel J O | Proteins bound to a marker or solid phase support matrix using a hydrazone linkage |
NO162946C (en) * | 1987-08-21 | 1990-03-14 | Otto Soerensen | DEVICE FOR MAGNETIC SEPARATION OF CELLS. |
US5599667A (en) * | 1987-03-02 | 1997-02-04 | Gen-Probe Incorporated | Polycationic supports and nucleic acid purification separation and hybridization |
US5079155A (en) * | 1987-03-02 | 1992-01-07 | E. I. Du Pont De Nemours And Company | Fluorocarbon polymer support for chromatographic separations, diagnostic assays and enzyme immobilization |
ES2054797T3 (en) | 1987-03-02 | 1994-08-16 | Gen Probe Inc | POLICATIONIC SUPPORTS TO PURIFY, SEPARATE AND HYBRID NUCLEIC ACIDS. |
DE3717211A1 (en) | 1987-05-22 | 1988-12-01 | Diagen Inst Molekularbio | DEVICE AND METHOD FOR SEPARATING AND CLEANING MOLECULES |
US4921805A (en) * | 1987-07-29 | 1990-05-01 | Life Technologies, Inc. | Nucleic acid capture method |
JPH01125395A (en) | 1987-07-29 | 1989-05-17 | Life Technol Inc | Nuclic acid catching reagent |
FR2619568B1 (en) | 1987-08-21 | 1989-07-07 | Centre Nat Rech Scient | POLYSTYRENE-DERIVED POLYMERS, PROCESSES FOR THE PREPARATION THEREOF AND APPLICATIONS THEREOF FOR THE ANALYSIS AND PURIFICATION OF ORGANIC MOLECULES |
US4908318A (en) * | 1987-09-04 | 1990-03-13 | Integrated Genetics, Inc. | Nucleic acid extraction methods |
US5585481A (en) | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
US4923978A (en) * | 1987-12-28 | 1990-05-08 | E. I. Du Pont De Nemours & Company | Process for purifying nucleic acids |
GB8800702D0 (en) * | 1988-01-13 | 1988-02-10 | Nycomed As | Test method & reagent kit therefor |
US5183809A (en) * | 1990-02-15 | 1993-02-02 | The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation | Cyclodextrin polymers and cyclodextrins immobilized on a solid surface |
CA1271996A (en) | 1988-03-09 | 1990-07-24 | David Lawrence Lynch | Variable gain encoder apparatus and method |
JP2791367B2 (en) | 1988-04-21 | 1998-08-27 | マイクロプローブ・コーポレーション | Nucleic acid extraction method |
US4952519A (en) | 1988-05-02 | 1990-08-28 | E. I. Du Pont De Nemours And Company | Protein immobilization with poly(ethyleneimine) derivatized with a hydroprobic group |
DE3921498A1 (en) * | 1988-09-28 | 1990-03-29 | Bayer Ag | POLYMER-TIED DYES, METHOD FOR THE PRODUCTION AND USE THEREOF |
US5807527A (en) | 1991-05-29 | 1998-09-15 | Flinders Technologies Pty. Ltd. | Solid medium and method for DNA storage |
CA1335181C (en) | 1988-10-11 | 1995-04-11 | R. Alan Hardwick | System for selective cell separation from cell concentrate |
IE883226L (en) | 1988-10-25 | 1990-04-25 | Dna Prep Galway Ltd S 22 | Separation of nucleic acids from protein material using¹cation exchangers |
US5028696A (en) | 1988-10-28 | 1991-07-02 | Torres Anthony R | Ion exchange and separation method |
US6448091B1 (en) | 1988-11-03 | 2002-09-10 | Igen International, Inc. | Method and apparatus for improved luminescence assays using particle concentration chemiluminescence detection |
US5512439A (en) * | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
GB8827160D0 (en) | 1988-11-21 | 1988-12-29 | Apothekernes Lab | Detection & quantitative determination of rna & dna |
GR1000347B (en) * | 1988-12-21 | 1992-06-25 | Ortho Diagnostic Systems Inc | Method of preparing nucleotide probes using a bridging complement |
WO1990008159A1 (en) | 1989-01-23 | 1990-07-26 | Invitron Corporation | Method for removing dna from protein preparations |
NL8900725A (en) | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | METHOD AND COMBINATION OF AGENTS FOR INSULATING NUCLEIC ACID. |
US5234809A (en) | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
JP2910929B2 (en) * | 1989-03-23 | 1999-06-23 | 浜松ホトニクス株式会社 | Surface modification method for particles composed of magnetic particles |
US5334499A (en) | 1989-04-17 | 1994-08-02 | Eastman Kodak Company | Methods of extracting, amplifying and detecting a nucleic acid from whole blood or PBMC fraction |
US4957605A (en) | 1989-04-17 | 1990-09-18 | Materials Research Corporation | Method and apparatus for sputter coating stepped wafers |
US5126028A (en) | 1989-04-17 | 1992-06-30 | Materials Research Corporation | Sputter coating process control method and apparatus |
US6010867A (en) * | 1989-04-19 | 2000-01-04 | Ibiden Co., Ltd. | Reagent for biomaterials assay, preparation method thereof, and assay method |
DE3916595A1 (en) | 1989-05-22 | 1990-11-29 | Boehringer Mannheim Gmbh | METHOD FOR NON-RADIOACTIVE MEASURING OF NUCLEIC ACID SYNTHESIS IN EUKARYONTIC CELLS |
NO168811C (en) | 1989-05-31 | 1992-04-08 | Dynal As | Separation device for separating magnetizable particles |
US5124444A (en) * | 1989-07-24 | 1992-06-23 | Microprobe Corporation | Lactam-containing compositions and methods useful for the extraction of nucleic acids |
EP0416748B1 (en) | 1989-08-07 | 1994-03-30 | J.T. Baker Inc. | Quaternised pei silica solid supports for chromatography |
US5032281A (en) * | 1989-08-09 | 1991-07-16 | Daicel Chemical Industries, Ltd. | Separating membrane and separation method |
US5128247A (en) * | 1989-08-14 | 1992-07-07 | Board Of Regents, The University Of Texas System | Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources |
US5084169A (en) * | 1989-09-19 | 1992-01-28 | The University Of Colorado Foundation, Inc. | Stationary magnetically stabilized fluidized bed for protein separation and purification |
US5433847A (en) * | 1989-11-01 | 1995-07-18 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Radial flow chromatography |
US5641628A (en) * | 1989-11-13 | 1997-06-24 | Children's Medical Center Corporation | Non-invasive method for isolation and detection of fetal DNA |
ATE162631T1 (en) | 1989-11-13 | 1998-02-15 | Childrens Medical Center | A NON-INVASIVE METHOD FOR SEPARATION AND DETECTION OF FETAL DNA |
US4997932A (en) * | 1989-11-13 | 1991-03-05 | Boehringer Mannheim Corporation | Method and kit for purifying nucleic acids |
US5000635A (en) * | 1989-11-17 | 1991-03-19 | The Boeing Company | Spring-loaded outboard side lock |
ATE147792T1 (en) | 1989-11-30 | 1997-02-15 | Pharmacia Biotech Ab | NEW METHOD FOR DETECTING A SPECIFIC NUCLEIC ACID SEQUENCE IN A CELL SAMPLE |
US5523231A (en) * | 1990-02-13 | 1996-06-04 | Amersham International Plc | Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules |
GB9003253D0 (en) | 1990-02-13 | 1990-04-11 | Amersham Int Plc | Precipitating polymers |
IT1240870B (en) * | 1990-02-14 | 1993-12-17 | Talent | PROCEDURE FOR THE EXTRACTION AND PURIFICATION OF HUMAN GENOMIC DNA |
CA2082936C (en) | 1990-05-15 | 2003-09-23 | Peter O. G. Arrhenius | Fluorescent porphyrin, and fluorescent phthalocyanine-polyethylene glycol, polyol, and saccharide derivatives as fluorescent probes |
US5234924A (en) | 1990-09-26 | 1993-08-10 | Adir Et Compagnie | Benzothiazine and benzothiazole compounds useful as analgesics |
DE4034036C2 (en) | 1990-10-26 | 1994-03-03 | Diagen Inst Molekularbio | Device and method for isolating nucleic acids from cell suspensions |
WO1992008133A1 (en) * | 1990-10-29 | 1992-05-14 | Dekalb Plant Genetics | Isolation of biological materials using magnetic particles |
US5234824A (en) | 1990-11-13 | 1993-08-10 | Specialty Laboratories, Inc. | Rapid purification of DNA |
US5654179A (en) | 1990-11-14 | 1997-08-05 | Hri Research, Inc. | Nucleic acid preparation methods |
DE4038293A1 (en) | 1990-11-28 | 1992-06-04 | Inst Molekularbiologie Ak | Nucleic acid adduct for in situ hybridisation to give nucleic acid sequences - comprises water soluble basic polymer and nucleic acid sequence formed by polymerase chain reaction and/or reverse transcriptase reaction |
US5204246A (en) * | 1990-12-26 | 1993-04-20 | Pioneer Hi-Bred International, Inc. | Dna isolation method |
US5296347A (en) * | 1991-02-08 | 1994-03-22 | Ciba Corning Diagnostics Corp. | Bridge immunoassay |
US5491223A (en) * | 1991-02-28 | 1996-02-13 | Daicel Chemical Industries, Ltd. | Polysaccharide derivative and separating agent |
GB9107124D0 (en) | 1991-04-05 | 1991-05-22 | Dynal As | Chemical process |
CA2067711C (en) | 1991-05-03 | 2000-08-08 | Daniel Lee Woodard | Solid phase extraction purification of dna |
US6251581B1 (en) * | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
US5155018A (en) | 1991-07-10 | 1992-10-13 | Hahnemann University | Process and kit for isolating and purifying RNA from biological sources |
FR2679255B1 (en) * | 1991-07-17 | 1993-10-22 | Bio Merieux | METHOD OF IMMOBILIZING A NUCLEIC FRAGMENT BY PASSIVE FIXING ON A SOLID SUPPORT, SOLID SUPPORT THUS OBTAINED AND ITS USE. |
CA2115061A1 (en) | 1991-08-06 | 1993-02-18 | David S. Sigman | Method of isolation of dna |
US5329000A (en) * | 1991-10-31 | 1994-07-12 | Becton, Dickinson And Company | Purification of DNA with silicon tetrahydrazide |
US6051380A (en) | 1993-11-01 | 2000-04-18 | Nanogen, Inc. | Methods and procedures for molecular biological analysis and diagnostics |
EP0555798B1 (en) | 1992-02-13 | 1999-05-06 | Becton, Dickinson and Company | Hydrated celite and purification of DNA |
DE4208645A1 (en) * | 1992-03-18 | 1993-09-23 | Bayer Ag | OPTICAL SOLID PHASE BIOSENSOR BASED ON FLUORESCENT COLOR-MARGINED POLYIONIC LAYERS |
DE4237381C1 (en) | 1992-11-05 | 1994-04-28 | Diagen Inst Molekularbio | Carrier material for the simultaneous binding of genotypic and phenotypic substances |
US5710028A (en) * | 1992-07-02 | 1998-01-20 | Eyal; Nurit | Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor |
GB9220773D0 (en) | 1992-10-02 | 1992-11-18 | Mini Agriculture & Fisheries | Detection of antigens and nucleic acids |
GB2272391A (en) | 1992-11-05 | 1994-05-18 | Gordon Henry Turner | Drilling jig |
GB9223334D0 (en) | 1992-11-06 | 1992-12-23 | Hybaid Ltd | Magnetic solid phase supports |
US5672659A (en) | 1993-01-06 | 1997-09-30 | Kinerton Limited | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
WO1994022918A1 (en) * | 1993-03-29 | 1994-10-13 | Minnesota Mining And Manufacturing Company | Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof |
US5438129A (en) * | 1993-09-27 | 1995-08-01 | Becton Dickinson And Company | DNA purification by solid phase extraction using partially fluorinated aluminum hydroxide adsorbant |
US5503816A (en) * | 1993-09-27 | 1996-04-02 | Becton Dickinson And Company | Silicate compounds for DNA purification |
GB2282138B (en) | 1993-09-28 | 1997-09-03 | Tosoh Corp | Method of extracting nucleic acids and method of detecting specified nucleic acid sequences |
US5919455A (en) | 1993-10-27 | 1999-07-06 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
US20030044777A1 (en) * | 1993-10-28 | 2003-03-06 | Kenneth L. Beattie | Flowthrough devices for multiple discrete binding reactions |
GB9323305D0 (en) | 1993-11-11 | 1994-01-05 | Medinnova Sf | Isoaltion of nucleic acid |
DE4432654C2 (en) | 1994-09-14 | 1998-03-26 | Qiagen Gmbh | Process for the isolation of nucleic acids from natural sources |
WO1995027718A2 (en) | 1994-04-08 | 1995-10-19 | Hybridon, Inc. | Purification of oligodeoxynucleotide phosphorothioates using anion exchange chromatography |
AU2907995A (en) | 1994-06-23 | 1996-01-19 | Dade International Inc. | Method for the rapid isolation of nucleic acid |
WO1996006262A1 (en) | 1994-08-25 | 1996-02-29 | Kabushiki Kaisha Iseki Kaihatsu Koki | Excavator for vertical bores |
US5622822A (en) * | 1994-09-13 | 1997-04-22 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same |
US5582988A (en) | 1994-09-15 | 1996-12-10 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same |
US5705628A (en) * | 1994-09-20 | 1998-01-06 | Whitehead Institute For Biomedical Research | DNA purification and isolation using magnetic particles |
US5652348A (en) * | 1994-09-23 | 1997-07-29 | Massey University | Chromatographic resins and methods for using same |
US5660984A (en) | 1994-12-09 | 1997-08-26 | Davis; Thomas E. | DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof |
GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
US5631146A (en) * | 1995-01-19 | 1997-05-20 | The General Hospital Corporation | DNA aptamers and catalysts that bind adenosine or adenosine-5'-phosphates and methods for isolation thereof |
US5762903A (en) | 1995-03-10 | 1998-06-09 | Korea Atomic Energy Research Institute | Radioactive chitosan complex for radiation therapy |
CN1094940C (en) * | 1995-04-28 | 2002-11-27 | 第一制药株式会社 | Pentacyclic compounds |
US5702147A (en) * | 1995-05-09 | 1997-12-30 | Bestop, Inc. | Tailgate sealing arrangement |
AR003122A1 (en) | 1995-05-19 | 1998-07-08 | Merck & Co Inc | A PROCESS FOR ISOLATION AND PURIFICATION OF PLASMIDS IN LARGE SCALE FERMENTATORS AND ISOLATED AND PURIFIED DNA OBTAINED THROUGH SUCH A PROCESS. |
DE19520398B4 (en) * | 1995-06-08 | 2009-04-16 | Roche Diagnostics Gmbh | Magnetic pigment |
WO1996041810A1 (en) | 1995-06-08 | 1996-12-27 | Progen Industries Limited | Method and apparatus for dna extraction |
JP2965131B2 (en) | 1995-07-07 | 1999-10-18 | 東洋紡績株式会社 | Magnetic carrier for nucleic acid binding and nucleic acid isolation method using the same |
EP0854765B1 (en) * | 1995-08-28 | 2001-04-04 | Advanced Nano Technologies Pty Ltd | Process for the production of ultrafine particles |
US5783686A (en) | 1995-09-15 | 1998-07-21 | Beckman Instruments, Inc. | Method for purifying nucleic acids from heterogenous mixtures |
US6677164B1 (en) | 1995-11-21 | 2004-01-13 | Novartis Ag | Multivalent polymers, processes for their preparation, and their use for preparing biologically active compounds |
US5612473A (en) * | 1996-01-16 | 1997-03-18 | Gull Laboratories | Methods, kits and solutions for preparing sample material for nucleic acid amplification |
US6803188B1 (en) | 1996-01-31 | 2004-10-12 | The Regents Of The University Of California | Tandem fluorescent protein constructs |
US5981735A (en) | 1996-02-12 | 1999-11-09 | Cobra Therapeutics Limited | Method of plasmid DNA production and purification |
SE9600590D0 (en) * | 1996-02-19 | 1996-02-19 | Pharmacia Biotech Ab | Methods for chromatographic separation of peptides and nucleic acid and new high-affinity ion exchange matrix |
JP4264134B2 (en) | 1996-02-25 | 2009-05-13 | プレシジョン・システム・サイエンス株式会社 | Biopolymer, microorganism or substance treatment method using multiple types of magnetic particles |
NO961221D0 (en) | 1996-03-26 | 1996-03-26 | Oeystein Fodstad | Method of identifying new genes associated with site-preferential cancer metastasis formation |
SE9601318D0 (en) * | 1996-04-04 | 1996-04-04 | Pharmacia Biosensor Ab | Method for nucleic acid analysis |
US5780319A (en) * | 1996-04-19 | 1998-07-14 | Pasteur Sanofi Diagnostics | Immunoassays to detect antiphospholipid antibodies |
US5916746A (en) * | 1996-05-09 | 1999-06-29 | Kirkegaard & Perry Laboratories, Inc. | Formazan-based immunoassay |
US5962412A (en) | 1996-06-10 | 1999-10-05 | Arqule, Inc. | Method of making polymers having specific properties |
US5981235A (en) | 1996-07-29 | 1999-11-09 | Promega Corporation | Methods for isolating nucleic acids using alkaline protease |
JP3793287B2 (en) | 1996-08-22 | 2006-07-05 | ペンタックス株式会社 | Method for isolating plasmid DNA |
CA2214495C (en) | 1996-09-25 | 2002-02-05 | Daniel L. Woodard | Hydrated zirconium silicate composition for purification of nucleic acids |
US5795748A (en) | 1996-09-26 | 1998-08-18 | Becton Dickinson And Company | DNA microwell device and method |
AU724492B2 (en) * | 1996-10-10 | 2000-09-21 | Biotechnology Research And Development Corporation | Polymer-protein composites and methods for their preparation and use |
DK0937096T3 (en) | 1996-11-06 | 2004-06-14 | Sequenom Inc | Method of mass spectrometry analysis |
US6060246A (en) * | 1996-11-15 | 2000-05-09 | Avi Biopharma, Inc. | Reagent and method for isolation and detection of selected nucleic acid sequences |
EP0853123A1 (en) | 1997-01-10 | 1998-07-15 | Roche Diagnostics GmbH | Purification of DNA by 'cross-flow-filtration' |
US6027945A (en) * | 1997-01-21 | 2000-02-22 | Promega Corporation | Methods of isolating biological target materials using silica magnetic particles |
US5770712A (en) * | 1997-03-14 | 1998-06-23 | Virginia Tech Intellectual Properties, Inc. | Crosslinked hydrogel beads from chitosan |
GB9709728D0 (en) * | 1997-05-13 | 1997-07-02 | Dynal As | Single step method |
US20040152084A1 (en) | 2003-01-31 | 2004-08-05 | Slattum Paul M. | Compounds and processes for single-pot attachment of a label to nucleic acid |
US5958788A (en) | 1997-05-28 | 1999-09-28 | Nalco Chemical Company | Luminol tagged polymers for treatment of industrial systems |
JP2002507121A (en) * | 1997-06-25 | 2002-03-05 | プロメガ コーポレイション | RNA isolation method |
EP0897978A3 (en) | 1997-08-22 | 2001-10-17 | Becton, Dickinson and Company | Zirconium oxide and related compounds for purification of nucleic acids |
DE19739218A1 (en) | 1997-09-08 | 1999-03-11 | Boehringer Mannheim Gmbh | Purification of substances from a biological sample |
JP4304348B2 (en) * | 1997-09-22 | 2009-07-29 | 独立行政法人理化学研究所 | DNA isolation method |
EP1025263A2 (en) | 1997-10-23 | 2000-08-09 | GUILLET, James Edwin | Labelling of polymers and sequencing of nucleic acids |
DE19746874A1 (en) | 1997-10-23 | 1999-04-29 | Qiagen Gmbh | Isolation of nucleic acids |
DE19747572C1 (en) | 1997-10-28 | 1999-04-08 | Inst Chemo Biosensorik | Apparatus for fluorescence immunoassay |
US6120985A (en) | 1997-10-31 | 2000-09-19 | Bbi Bioseq, Inc. | Pressure-enhanced extraction and purification |
GB9725197D0 (en) | 1997-11-29 | 1998-01-28 | Secr Defence | Detection system |
US6914137B2 (en) | 1997-12-06 | 2005-07-05 | Dna Research Innovations Limited | Isolation of nucleic acids |
DE69839133T2 (en) | 1997-12-06 | 2009-02-05 | Invitrogen Corp., Carlsbad | Isolation of nucleic acids |
EP1062515B1 (en) * | 1998-02-12 | 2009-11-25 | Immunivest Corporation | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
FR2777355B1 (en) | 1998-04-10 | 2000-05-12 | Bio Merieux | PROCESS FOR FIXING A BIOLOGICAL MOLECULE ON THE SURFACE OF A SUPPORT CONSISTING OF SILICA OR METAL OXIDE |
US7078224B1 (en) | 1999-05-14 | 2006-07-18 | Promega Corporation | Cell concentration and lysate clearance using paramagnetic particles |
US6194562B1 (en) * | 1998-04-22 | 2001-02-27 | Promega Corporation | Endotoxin reduction in nucleic acid purification |
US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
US6534262B1 (en) * | 1998-05-14 | 2003-03-18 | Whitehead Institute For Biomedical Research | Solid phase technique for selectively isolating nucleic acids |
US6287765B1 (en) | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
US6245507B1 (en) * | 1998-08-18 | 2001-06-12 | Orchid Biosciences, Inc. | In-line complete hyperspectral fluorescent imaging of nucleic acid molecules |
AU2025400A (en) | 1998-11-17 | 2000-06-05 | Proteo Tools | Separation, screening, and identification of biological targets |
AU764964B2 (en) | 1998-11-23 | 2003-09-04 | Usamriid | Purification method and apparatus |
FI990082A0 (en) | 1999-01-18 | 1999-01-18 | Labsystems Oy | Purification process using magnetic particles |
AU2862100A (en) | 1999-01-27 | 2000-08-18 | Folim G. Halaka | Materials and methods for the purification of polyelectrolytes |
DE60021855T2 (en) | 1999-01-29 | 2006-05-18 | Amersham Biosciences K.K. | TEMPERATURE-SENSITIVE POLYMER AND METHOD FOR THE PRODUCTION THEREOF |
DE19907023A1 (en) | 1999-02-19 | 2000-08-24 | Bayer Ag | Isolation of nucleic acids, useful for e.g. genetic diagnosis by amplification, by adsorption onto polymeric beads at neutral or acidic pH then release at basic pH |
GB9907245D0 (en) | 1999-03-29 | 1999-05-26 | Goldsborough Andrew | Cleavage of nucleic acids from solid supports |
AU4058100A (en) | 1999-04-09 | 2000-11-14 | Arcturus Engineering, Inc. | Generic cdna or protein array for customized assays |
CA2270106C (en) | 1999-04-23 | 2006-03-14 | Yousef Haj-Ahmad | Nucleic acid purification and process |
US6270970B1 (en) | 1999-05-14 | 2001-08-07 | Promega Corporation | Mixed-bed solid phase and its use in the isolation of nucleic acids |
US6310199B1 (en) | 1999-05-14 | 2001-10-30 | Promega Corporation | pH dependent ion exchange matrix and method of use in the isolation of nucleic acids |
EP1179058B1 (en) | 1999-05-14 | 2011-08-24 | Promega Corporation | Cell concentration and lysate clearance using paramagnetic particles |
US6472141B2 (en) | 1999-05-21 | 2002-10-29 | Caliper Technologies Corp. | Kinase assays using polycations |
US6645733B1 (en) | 1999-06-25 | 2003-11-11 | Ingeneus Corporation | Fluorescent intensity method for assaying binding between proteins or peptides |
ES2258429T3 (en) * | 1999-07-15 | 2006-09-01 | Qiagen Gmbh | METHODS TO SEPARATE SUBSTRATES IN PARTICLES OF A SOLUTION, AT THE TIME THAT THE LOSS OF PARTICLES IS MINIMIZED. |
WO2001038585A2 (en) | 1999-11-24 | 2001-05-31 | The Regents Of The University Of California | Polymer arrays and methods of using labeled probe molecules to identify and quantify target molecule expression |
US6582907B1 (en) * | 1999-12-09 | 2003-06-24 | Pharmacia & Upjohn Company | Use of fluorescence correlation spectroscopy to identify compounds that bind to target species under isothermal denaturing conditions |
US6638906B1 (en) * | 1999-12-13 | 2003-10-28 | Nobex Corporation | Amphiphilic polymers and polypeptide conjugates comprising same |
US6489160B2 (en) | 2000-03-16 | 2002-12-03 | Kabushiki Kaisha Toshiba | Method for producing nucleic acid strand immobilized carrier |
US7078536B2 (en) | 2001-03-14 | 2006-07-18 | Genesoft Pharmaceuticals, Inc. | Charged compounds comprising a nucleic acid binding moiety and uses therefor |
US7262006B1 (en) | 2000-05-01 | 2007-08-28 | Ortho-Clinical Diagnostics, Inc. | Rapid and efficient capture of DNA from sample without using cell lysing reagent |
GB0013658D0 (en) | 2000-06-05 | 2000-07-26 | Dynal Asa | Nucleic acid isolation |
WO2002010373A2 (en) | 2000-07-31 | 2002-02-07 | Applera Corporation | Apparatus and method for specific release of captured extension products |
WO2002016580A2 (en) | 2000-08-24 | 2002-02-28 | Bio-Rad Laboratories, Inc. | Flow-through system for lysate clarification and nucleic acid binding in a single step |
US6627748B1 (en) | 2000-09-11 | 2003-09-30 | The Trustees Of Columbia University In The City Of New York | Combinatorial fluorescence energy transfer tags and their applications for multiplex genetic analyses |
GB0026560D0 (en) * | 2000-10-30 | 2000-12-13 | Novartis Ag | Organic compounds |
EP1207207B1 (en) | 2000-11-20 | 2004-10-27 | Sony International (Europe) GmbH | Process for immobilization of nucleic acid molecules on a substrate |
US6743586B2 (en) * | 2001-01-29 | 2004-06-01 | The United States Of America As Represented By The Secretary Of The Commerce | Rapid fluorescence detection of binding to nucleic acid drug targets labelled with highly fluorescent nucleotide base analogs |
WO2002070020A2 (en) * | 2001-03-02 | 2002-09-12 | University Of Western Ontario | Polymer precursors of radiolabeled compounds, and methods of making and using the same |
JP3975319B2 (en) | 2001-03-02 | 2007-09-12 | 富士ゼロックス株式会社 | Developing device and image forming apparatus using the same |
AU2002258997A1 (en) | 2001-04-24 | 2002-11-05 | Li-Cor, Inc. | Polymerases with charge-switch activity and methods of generating such polymerases |
US7338805B2 (en) * | 2001-05-04 | 2008-03-04 | Bio Merieux | Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules |
US7183116B2 (en) * | 2001-05-14 | 2007-02-27 | The Institute For Systems Biology | Methods for isolation and labeling of sample molecules |
US20030124742A1 (en) * | 2001-08-22 | 2003-07-03 | Prakash Ramesh K. | Conjugates targeted to target receptors |
US20030099954A1 (en) * | 2001-11-26 | 2003-05-29 | Stefan Miltenyi | Apparatus and method for modification of magnetically immobilized biomolecules |
US20030229013A1 (en) | 2001-12-07 | 2003-12-11 | Shih-Kwang Wu | Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same |
US7056682B2 (en) * | 2001-12-27 | 2006-06-06 | Matsushita Electric Industrial Co., Ltd. | Immunoassay method and immunoassay reagent kit to be used therein |
US20030147958A1 (en) | 2002-01-29 | 2003-08-07 | Cheol-Hee Ahn | Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents |
WO2003083440A2 (en) * | 2002-03-29 | 2003-10-09 | Genentech, Inc. | Methods and compositions for detection and quantitation of nucleic acid analytes |
GB0209539D0 (en) * | 2002-04-26 | 2002-06-05 | Avecia Ltd | Monomer Polymer and process |
GB0212826D0 (en) | 2002-05-31 | 2002-07-10 | Dna Res Innovations Ltd | Materials and methods relating to polyions and substance delivery |
EP1534857B1 (en) | 2002-06-20 | 2010-08-04 | The Regents of The University of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
DK1411122T3 (en) | 2002-10-18 | 2008-11-03 | Sloning Biotechnology Gmbh | Process for Preparation of Nucleic Acid Molecules |
FR2847581B1 (en) * | 2002-11-21 | 2007-03-23 | Commissariat Energie Atomique | METHOD FOR FIXING A PROTEIN ON A POLYMER BASED ON PYRROLE AND ITS USE IN THE MANUFACTURE OF A SENSOR |
GB0229287D0 (en) | 2002-12-16 | 2003-01-22 | Dna Res Innovations Ltd | Polyfunctional reagents |
US20050123932A1 (en) * | 2003-12-09 | 2005-06-09 | Mekbib Astatke | Nucleic acid-chelating agent conjugates |
BE1016163A6 (en) | 2004-08-18 | 2006-04-04 | Mc Anton Sa | METHOD Percutaneous HYPERBARIC OXYGEN SPRAY fluorocarbons. |
-
1994
- 1994-12-12 GB GBGB9425138.6A patent/GB9425138D0/en active Pending
-
1995
- 1995-12-12 DE DE69533317T patent/DE69533317T2/en not_active Expired - Lifetime
- 1995-12-12 CA CA002207608A patent/CA2207608C/en not_active Expired - Fee Related
- 1995-12-12 WO PCT/GB1995/002893 patent/WO1996018731A2/en active IP Right Grant
- 1995-12-12 AT AT95940351T patent/ATE272110T1/en active
- 1995-12-12 JP JP51846396A patent/JP3787354B2/en not_active Expired - Lifetime
- 1995-12-12 EP EP95940351A patent/EP0796327B1/en not_active Revoked
- 1995-12-12 AU AU41829/96A patent/AU706211B2/en not_active Expired
- 1995-12-12 US US08/849,686 patent/US20040215011A1/en not_active Abandoned
-
2005
- 2005-09-23 US US11/234,001 patent/US7173124B2/en not_active Expired - Fee Related
-
2007
- 2007-02-05 US US11/671,426 patent/US20070190559A1/en not_active Abandoned
-
2008
- 2008-03-24 US US12/054,332 patent/US7989614B2/en not_active Expired - Fee Related
- 2008-05-30 US US12/130,926 patent/US20090068724A1/en not_active Abandoned
- 2008-05-30 US US12/130,959 patent/US20090149646A1/en not_active Abandoned
-
2011
- 2011-06-14 US US13/160,428 patent/US8691969B2/en not_active Expired - Fee Related
-
2014
- 2014-02-19 US US14/183,999 patent/US20140291576A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993025912A2 (en) * | 1992-06-09 | 1993-12-23 | Medical Research Council | Automated preparation of nucleic acids |
Non-Patent Citations (6)
Title |
---|
D.A. JACKSON ET AL.: "A general method for preparing chromatin containing intact DNA", EMBO JOURNAL, vol. 4, no. 4, 1985, pages 913 - 918, XP002007387 * |
G. KONAT ET AL.: "Rapid isolation of genomin DNA from animal Tissues", EXPERIMENTAL CELL RESEARCH, vol. 190, 1990, pages 294 - 296, XP002007389 * |
K. SMALLA ET AL.: "Rapid DNA extraction protocol from soil for polymerase chain reaction mediated amplification", JOURNAL OF APPLIED BACTERIOLOGY, vol. 74, 1993, pages 78 - 85, XP002007385 * |
M.I. MORE ET AL.: "Quantitative cell lysis of indogenous microorganisms and rapid extraction of microbial DNA from sediment", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 60, no. 5, 1994, pages 1572 - 1580, XP002007386 * |
P.M. GLEE ET AL.: "Methods for DNA extraction from Candida albicans", ANALYTICAL BIOCHEMISTRY, vol. 164, 1987, pages 207 - 213, XP002007390 * |
P.R. COOK: "A general method for preparing intact nuclear DNA", EMBO JOURNAL, vol. 3, no. 8, 1984, pages 1837 - 1842, XP002007388 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8691969B2 (en) | 1994-12-12 | 2014-04-08 | Life Technologies As | Isolation of nucleic acid |
US8026068B2 (en) | 2002-01-08 | 2011-09-27 | Roche Molecular Systems, Inc. | Use of silica material in an amplification reaction |
US8101744B2 (en) | 2007-04-20 | 2012-01-24 | Roche Diagnostics Operations, Inc. | Isolation and purification of nucleic acids with a solid phase |
US11845081B2 (en) | 2007-07-13 | 2023-12-19 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
Also Published As
Publication number | Publication date |
---|---|
JP3787354B2 (en) | 2006-06-21 |
EP0796327A2 (en) | 1997-09-24 |
DE69533317D1 (en) | 2004-09-02 |
EP0796327B1 (en) | 2004-07-28 |
WO1996018731A2 (en) | 1996-06-20 |
GB9425138D0 (en) | 1995-02-08 |
US20080300396A1 (en) | 2008-12-04 |
JPH11501504A (en) | 1999-02-09 |
AU4182996A (en) | 1996-07-03 |
US20140291576A1 (en) | 2014-10-02 |
US7173124B2 (en) | 2007-02-06 |
US20110251382A1 (en) | 2011-10-13 |
US20060058519A1 (en) | 2006-03-16 |
DE69533317T2 (en) | 2005-12-01 |
US20070190559A1 (en) | 2007-08-16 |
CA2207608A1 (en) | 1996-06-20 |
US20090149646A1 (en) | 2009-06-11 |
US7989614B2 (en) | 2011-08-02 |
CA2207608C (en) | 2009-04-07 |
US8691969B2 (en) | 2014-04-08 |
ATE272110T1 (en) | 2004-08-15 |
AU706211B2 (en) | 1999-06-10 |
US20040215011A1 (en) | 2004-10-28 |
US20090068724A1 (en) | 2009-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1996018731A3 (en) | Isolation of nucleic acid | |
GB9709728D0 (en) | Single step method | |
AU600997B2 (en) | Method of isolating and purifying nucleic acids from biological samples | |
ATE365225T1 (en) | METHOD AND MEANS FOR ISOLATION OF MICROORGANISMS | |
AU6380001A (en) | Porous ferro- or ferrimagnetic glass particles for isolating molecules | |
EP0875584A3 (en) | Nucleic acid assays | |
AU2331095A (en) | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay | |
ATE284891T1 (en) | ISOLATION OF SINGLE STRANDED NUCLEIC ACIDS | |
ATE513039T1 (en) | NUCLEIC ACID ISOLATION METHOD AND CORRESPONDING REAGENT SET THEREOF | |
WO1997005248A3 (en) | Solution containing chaotropic agent and process using it for isolation of dna, rna and proteins | |
CA2286573A1 (en) | Nucleic acid archiving | |
AU7225591A (en) | Nucleic acid enzymes for cleaving dna | |
EP0261956A3 (en) | Process for rapid isolation of high molecular weight dna | |
WO1999007887A3 (en) | A method of removing nucleic acid contamination in amplification reactions | |
AU2929495A (en) | Nucleic acid sequence amplification method | |
ATE335815T1 (en) | ISOLATION OF NUCLEIC ACIDS | |
WO2001014590A3 (en) | Simultaneous isolation and quantitation of dna | |
EP0261955A3 (en) | Process for immobilization of dna | |
WO2001055708A3 (en) | Method of processing a sample containing at least one biological element | |
AU3107699A (en) | Novel forms of t cell costimulatory proteins, nucleic acid molecules, and uses thereof | |
WO2000040757A3 (en) | Method of identifying nucleic acids | |
WO1996019587A3 (en) | Methods of immobilizing oligonucleotides to solid support materials and methods of using support bound oligonucleotides | |
WO1999032616A3 (en) | Method for isolating short and long-chain nucleic acids | |
AU6281200A (en) | Laboratory robot and method and reagent kit for isolating nucleic acids | |
AU1911395A (en) | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IS JP KE KG KP KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TT UA UG US UZ VN |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU IS JP KE KG KP KR KZ LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TT UA UG US UZ VN |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2207608 Country of ref document: CA Ref country code: CA Ref document number: 2207608 Kind code of ref document: A Format of ref document f/p: F Ref country code: JP Ref document number: 1996 518463 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1995940351 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 08849686 Country of ref document: US |
|
WWP | Wipo information: published in national office |
Ref document number: 1995940351 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWG | Wipo information: grant in national office |
Ref document number: 1995940351 Country of ref document: EP |